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1

Wang, Han, Yaxuan Sun, Xuan Ma, Tianyu Yang, and Feng Wang. "The Lactobacillus plantarum P-8 Probiotic Microcapsule Prevents DSS-Induced Colitis through Improving Intestinal Integrity and Reducing Colonic Inflammation in Mice." Nutrients 16, no. 7 (2024): 1055. http://dx.doi.org/10.3390/nu16071055.

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Probiotics, recognized as beneficial and active microorganisms, often face challenges in maintaining their functionality under harsh conditions such as exposure to stomach acid and bile salts. In this investigation, we developed probiotic microcapsules and assessed their protective effects and underlying mechanisms in a murine model of dextran sulfate sodium (DSS)-induced colitis using male C57BL/6J mice. The administration of the probiotic microcapsules significantly mitigated body weight loss, prevented colon length shortening, decreased the disease activity index scores, and reduced histopa
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2

Déchelotte, Pierre, Jonathan Breton, Clémentine Trotin-Picolo, et al. "The Probiotic Strain H. alvei HA4597® Improves Weight Loss in Overweight Subjects under Moderate Hypocaloric Diet: A Proof-of-Concept, Multicenter Randomized, Double-Blind Placebo-Controlled Study." Nutrients 13, no. 6 (2021): 1902. http://dx.doi.org/10.3390/nu13061902.

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Background: Increasing evidence supports the role of the gut microbiota in the control of body weight and feeding behavior. Moreover, recent studies have reported that the probiotic strain Hafnia alvei HA4597® (HA), which produces the satietogenic peptide ClpB mimicking the effect of alpha-MSH, reduced weight gain and adiposity in rodent models of obesity. Methods: To investigate the clinical efficacy of HA, 236 overweight subjects were included, after written informed consent, in a 12-week prospective, double-blind, randomized study. All subjects received standardized counselling for a −20% h
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3

Sergeev, Igor N., Thamer Aljutaily, Gemma Walton, and Eduardo Huarte. "Effects of Synbiotic Supplement on Human Gut Microbiota, Body Composition and Weight Loss in Obesity." Nutrients 12, no. 1 (2020): 222. http://dx.doi.org/10.3390/nu12010222.

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Targeting gut microbiota with synbiotics (probiotic supplements containing prebiotic components) is emerging as a promising intervention in the comprehensive nutritional approach to reducing obesity. Weight loss resulting from low-carbohydrate high-protein diets can be significant but has also been linked to potentially negative health effects due to increased bacterial fermentation of undigested protein within the colon and subsequent changes in gut microbiota composition. Correcting obesity-induced disruption of gut microbiota with synbiotics can be more effective than supplementation with p
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Bogdanova, Elena S., Maria A. Danilova, Maria S. Smirnova, et al. "Grass Meal Acts as a Probiotic in Chicken." Microbiology Research 14, no. 4 (2023): 1633–52. http://dx.doi.org/10.3390/microbiolres14040113.

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Probiotics can act as an alternative to antibiotics in animal feeding, but their use is minimal due to their expensive production. Dry grass is rich with bacteria beneficial for animal feeding and can be used as a probiotic. However, data about the quantitative dependence of the grass microbiome on environmental factors and seasons remain insufficient for preparing “grass-meal-based probiotics”. Four grass samples were collected in two geographically remote regions of Russia; their microbiome was characterized by metagenomic sequencing of 16S rDNA libraries and microbiological seeding, and bio
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Li, Mengna, Xintong Liu, Weijian Chen, et al. "Alleviating Effect of Lactiplantibacillus plantarum HYY-S10 on Colitis in Mice Based on an Analysis of the Immune Axis in the Intestine." Microorganisms 13, no. 4 (2025): 840. https://doi.org/10.3390/microorganisms13040840.

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The pathogenesis of ulcerative colitis (UC) has been fundamentally associated with intestinal microbiota dysbiosis and disruption of immune homeostasis. This study systematically investigates the therapeutic potential of Lactiplantibacillus plantarum HYY-S10 (HYY-S10), a novel strain isolated from De’ang sour tea in Yun an, China, with a focus on its mechanisms for alleviating colitis through the modulation of gut microbiota. Using a dextran sulfate sodium (DSS)-induced colitis model in C57BL/6J mice, our findings demonstrated that seven days of oral supplementation with HYY-S10 (1 × 108 CFU/m
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6

Cheng, Ruyue, and Fang He. "Contributions of Lactobacillus plantarum PC170 Administration on the Reconstruction of Gut Microbiota After Short-Term Ceftriaxone Exposure in Mice." Current Developments in Nutrition 4, Supplement_2 (2020): 1548. http://dx.doi.org/10.1093/cdn/nzaa062_005.

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Abstract Objectives This study aimed to determine whether Lactobacillus plantarum PC170 (PC170) could alleviate the dysbiosis of gut microbiota, altered growth, and inflammatory response caused by short-term antibiotic treatment in mice. Methods The impact of probiotics concurrent with antibiotic treatment and/or during the recovery phase after antibiotic treatment on the body weight, fecal bacterial composition, short-chain fatty acids (SCFAs) concentration, and splenic cytokine mRNA expression of mice were examined. Results Orally administrated ceftriaxone quantitatively and significantly de
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7

Augustynowicz, Gabriela, Maria Lasocka, Hubert Paweł Szyller, et al. "The Role of Gut Microbiota in the Development and Treatment of Obesity and Overweight: A Literature Review." Journal of Clinical Medicine 14, no. 14 (2025): 4933. https://doi.org/10.3390/jcm14144933.

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The gut microbiota, dominated by bacteria from the Firmicutes, Bacteroidetes, Proteobacteria, and Actinobacteria phyla, plays an essential role in fermenting indigestible carbohydrates, regulating metabolism, synthesizing vitamins, and maintaining immune functions and intestinal barrier integrity. Dysbiosis is associated with obesity development. Shifts in the ratio of Firmicutes to Bacteroidetes, particularly an increase in Firmicutes, may promote enhanced energy storage, appetite dysregulation, and increased inflammatory processes linked to insulin resistance and other metabolic disorders. T
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8

Min, Mildred, Anurag Tarmaster, Apple Bodemer, and Raja K. Sivamani. "The Influence of a Plant-Based Diet on Skin Health: Inflammatory Skin Diseases, Skin Healing, and Plant-Based Sources of Micro- and Macro-Nutrients." Life 14, no. 11 (2024): 1439. http://dx.doi.org/10.3390/life14111439.

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Dietary patterns have been shown to worsen or alleviate several dermatological diseases. A well-balanced, plant-based diet is known to have anti-inflammatory, probiotic, and antioxidant properties, along with weight loss-promoting effects. Moreover, a plant-based diet has a low glycemic load, improving metabolic disease. Due to these qualities, plant-based diets may have beneficial effects on inflammatory skin conditions. In this review, we aim to discuss the possible mechanisms by which a plant-based diet reduces disease severity in psoriasis, acne, hidradenitis suppurativa, and atopic dermat
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9

Goldiș, Adrian, Radu Dragomir, Marina Adriana Mercioni, et al. "Introducing a Novel Personalized Microbiome-Based Treatment for Inflammatory Bowel Disease: Results from NostraBiome’s Internal Validation Study." Biomedicines 13, no. 4 (2025): 795. https://doi.org/10.3390/biomedicines13040795.

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Background/Objectives: Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn’s disease, is characterized by chronic gut inflammation driven by microbial dysbiosis and immune dysfunction. Current therapies primarily involve anti-inflammatory and immunomodulatory strategies; however, many patients experience an inadequate response or a gradual loss of efficacy over time. This study evaluates the clinical efficacy of personalized microbiome modulation (PMM)—an AI-driven intervention designed to restore microbial balance and improve key treatment outcomes such as symptom cont
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10

Ferro, Domenico, Francesco Baratta, Daniele Pastori, et al. "New Insights into the Pathogenesis of Non-Alcoholic Fatty Liver Disease: Gut-Derived Lipopolysaccharides and Oxidative Stress." Nutrients 12, no. 9 (2020): 2762. http://dx.doi.org/10.3390/nu12092762.

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Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. The intricate NAFLD pathogenesis is summarized by the multiple-hits hypothesis, which combines all the environmental and genetic factors that promote the development of NAFLD into a single scenario. Among these, bacterial lipopolysaccharides (LPS) are derived from the overgrowth of Gram-negative bacteria and translocated mainly as a consequence of enhanced intestinal permeability. Furthermore, oxidative stress is increased in NAFLD as a consequence of reactive oxygen species (ROS) overproduction and a
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11

Salikova, S. P., V. B. Grinevich, and A. A. Vlasov. "The Modern Aspects of Nutrition during Chronic Heart Failure." Experimental and Clinical Gastroenterology, no. 12 (January 15, 2022): 62–73. http://dx.doi.org/10.31146/1682-8658-ecg-196-12-62-73.

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Nutrition occupies one of the important places in the programs of prevention and non-drug therapy of CHF and associated diseases. At the same time, the validity of dietary recommendations to patients regarding salt intake, dietary habits and the use of individual nutraceuticals is questionable. The purpose of this review is to present up-to-date data of clinical and experimental studies concerning sodium restriction, the use of various diets, nutraceuticals, and means for correcting intestinal dysbiosis in CHF. Materials and methods: the articles are searched in the databases eLibraryRU and Me
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12

Jiang, Yan, Rachel Farias, Ashley E. Holly, et al. "The DIET study: A randomized controlled trial of a high fiber diet intervention (HFDI) in patients (pts) with melanoma receiving immune checkpoint blockade (ICB)." Journal of Clinical Oncology 42, no. 16_suppl (2024): 9558. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.9558.

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9558 Background: Multiple studies support that the gut microbiome plays a key role in response to ICB. Habitual high dietary fiber intake is associated with improved response to ICB and high fiber diet interventions have been shown to favorably modulate the microbiome in non-cancer populations. We therefore conducted a randomized trial of HFDI versus healthy control diet in melanoma pts receiving ICB. Methods: 45 melanoma pts starting ICB (21 adjuvant, 12 neoadjuvant, 12 advanced unresectable) were enrolled. Pts were randomized 2:1 to HFDI (30 to 50 g/day by ramp-up) or control (20 g) stratifi
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13

Cogrossi, Laura Lucia, Matteo Grioni, Paola Zordan, et al. "Exploiting the Gut Microbiota to Boost Immunotherapy and Switch the Trajectory of Multiple Myeloma." Blood 142, Supplement 1 (2023): 754. http://dx.doi.org/10.1182/blood-2023-180145.

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Clonal proliferation of neoplastic plasma cells in the bone marrow (BM) and organ dysfunction characterizes multiple myeloma (MM), a treatable but incurable disease. Although asymptomatic smoldering MM (SMM) often precedes full blown MM, most patients affected by SMM are only offered active observation, which increases their frustration and anxiety. In transgenic Vk*MYC mice developing de novo MM, we found a direct link between gut microbiota composition and T helper 17 (Th17) lymphocytes, which migrated from the gut to the BM during asymptomatic MM (Early-MM), and favored the expansion of neo
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14

Joseph, Wilson. "BioFit Probiotic Ingredients On Amazon By Official Website." May 23, 2021. https://doi.org/10.5281/zenodo.4781919.

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BioFit Probiotic is a supplement to help you lose weight - without having to cut out all the food that you love. BioFit Probiotic is an effective, all-natural probiotic, which is designed to help users lose more than three pounds of fat every week. The supplement produces amazing results by focusing on the benefits of probiotics to the digestive system. It integrates multiple strains of probiotic bacteria, which naturally trigger the body to facilitate weight loss. <strong>BIOFIT SUPPLEMENT OFFICIAL WEBSITE</strong> BioFit Probiotic is a daily weight-loss supplement that includes a combination
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15

Michael, D. R., T. S. Davies, A. A. Jack, et al. "Daily supplementation with the Lab4P probiotic consortium induces significant weight loss in overweight adults." Scientific Reports 11, no. 1 (2021). http://dx.doi.org/10.1038/s41598-020-78285-3.

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AbstractThis 9-month randomised, parallel, double-blind, single-centre, placebo-controlled study (PROBE, ISRCTN18030882) assessed the impact of probiotic supplementation on bodyweight. Seventy overweight Bulgarian participants aged 45–65 years with BMI 25–29.9 kg/m2 received a daily dose of the Lab4P probiotic comprising lactobacilli and bifidobacteria (50 billion cfu/day). Participants maintained their normal diet and lifestyle over the duration of the study. The primary outcome was change from baseline in body weight and secondary outcomes included changes in waist circumference, hip circumf
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16

Cook, Chad M., DeAnn J. Liska, and Libertie B. Mantilla. "Probiotics for Weight Loss: Assessing the Evidence." FASEB Journal 31, S1 (2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.965.38.

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Emerging randomized controlled trials (RCTs) have suggested probiotics benefit weight loss or attenuate weight gain in adult humans. Recent meta‐analyses of these RCTs, however, have been inconclusive or conflicting. For example, one meta‐analysis concluded probiotics had no significant effect on body weight, with a mean difference of −1.77 kg (95% CI, −4.84 to 1.29 kg) comparing probiotics vs. placebo. In contrast, another meta‐analyis published in the same timeframe indicated probiotic consumption significantly reduced body weight by −0.59 kg (95% CI, −0.87 to −0.30 kg) vs. placebo. To under
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17

Hua, Dengxiong, Qin Yang, Xiaowei Li, et al. "The combination of Clostridium butyricum and Akkermansia muciniphila mitigates DSS-induced colitis and attenuates colitis-associated tumorigenesis by modulating gut microbiota and reducing CD8 + T cells in mice." mSystems, January 22, 2025. https://doi.org/10.1128/msystems.01567-24.

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ABSTRACT The gut microbiota is closely associated with inflammatory bowel disease (IBD) and colorectal cancer (CRC). Probiotics such as Clostridium butyricum (CB) or Akkermansia muciniphila (AKK) have the potential to treat inflammatory bowel disease (IBD) or colorectal cancer (CRC). However, research on the combined therapeutic effects and immunomodulatory mechanisms of CB and AKK in treating IBD or CRC has never been studied. This study evaluates the potential of co-administration of CB and AKK in treating DSS/AOM-induced IBD and colitis-associated CRC. Our results indicate that compared to
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18

Huang, Cuilan, Wujuan Hao, Xuyang Wang, Renmin Zhou, and Qiong Lin. "Probiotics for the treatment of ulcerative colitis: a review of experimental research from 2018 to 2022." Frontiers in Microbiology 14 (July 6, 2023). http://dx.doi.org/10.3389/fmicb.2023.1211271.

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Ulcerative colitis (UC) has become a worldwide public health problem, and the prevalence of the disease among children has been increasing. The pathogenesis of UC has not been elucidated, but dysbiosis of the gut microbiota is considered the main cause of chronic intestinal inflammation. This review focuses on the therapeutic effects of probiotics on UC and the potential mechanisms involved. In animal studies, probiotics have been shown to alleviate symptoms of UC, including weight loss, diarrhea, blood in the stool, and a shortened colon length, while also restoring intestinal microecological
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Han, Huan, Hui Xiong, Zengli Liu, et al. "Pasteurized Akkermansia muciniphila Timepie001 ameliorates DSS-induced ulcerative colitis in mice by alleviating intestinal injury and modulating gut microbiota." Frontiers in Microbiology 16 (February 19, 2025). https://doi.org/10.3389/fmicb.2025.1542522.

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IntroductionAkkermansia muciniphila (A. muciniphila), known as a next-generation probiotic, has been widely recognized for its beneficial effects in various metabolic diseases. While there is not much research whether live or pasteurized A. muciniphila has different effects on intestinal health.MethodsIn the present study, a strain of A. muciniphila was isolated from healthy individuals, with the live and pasteurized A. muciniphila named Timepie001 and Timepie001+, respectively. They were administered to dextran sulfate sodium-induced ulcerative colitis mice to investigate their influences on
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20

Neuron, IQ. "Neuron IQ Brain Support (#1 PREMIUM BRAIN BOOSTER FORMULA) Shocking Result!" November 15, 2022. https://doi.org/10.5281/zenodo.7322890.

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<strong>&bull; Product Name - </strong><strong>Neuron IQ</strong> <strong><strong>&bull; </strong>Category - Brain Booster Pills</strong> <strong><strong>&bull; </strong>Dosage - Take 2 Pills IN A DAY</strong> <strong><strong>&bull; </strong>Price - $7.99 per bottle</strong> <strong><strong>&bull; </strong>Result - 2-3 Months</strong> <strong><strong>&bull; </strong>Unit count - (60 Capsules) BOX</strong> <strong><strong>&bull; </strong>Official Website - Click Here</strong> <strong>VISIT THE OFFICIAL WEBSITE OF Neuron IQ Capsules TO ORDER</strong> Neuron IQ is a nootropics supplement that is
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De Oliveira Cavalcanti, Ellen Bethânia, Gustavo Cancian Baioto, Clairton Marcolongo-Pereira, Mayara Coutinho Carlos de Souza, Alice Corrêa Rassele, and Rodrigo Dos Santos Horta. "Congenital Extrahepatic Portosystemic Deviation in a Mixed-Breed Dog." Acta Scientiae Veterinariae 47 (January 25, 2019). http://dx.doi.org/10.22456/1679-9216.89524.

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Background: Portosystemic deviation (PSD) is a congenital or acquired vascular anomaly that allows an abnormal blood flow from the portal vein directly to the systemic circulation. This liver by-pass avoids hepatic metabolism of several toxins. Congenital PSDs are usually solitary and extra-hepatic, with a high incidence in pure-breed dogs. Acquired PSDs are usually multiple and occur as a consequence of portal hypertension. Surgery is the definitive treatment. Clinicians and surgeons may present difficulties in the propaedeutic of animals with PSD. This paper aims at reporting a successful su
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22

Li, Zhaojie, Chuantao Peng, Yaru Sun, et al. "Both viable Bifidobacterium longum subsp. infantis B8762 and heat-killed cells alleviate the intestinal inflammation of DSS-induced IBD rats." Microbiology Spectrum, April 22, 2024. http://dx.doi.org/10.1128/spectrum.03509-23.

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ABSTRACT In view of the safety concerns of probiotics, more and more attention is paid to the beneficial effects of dead probiotics cells. Herein, we investigated and compared the alleviation effects of viable Bifidobacterium longum subsp. infantis B8762 ( B. infantis B8762) and its heat-killed cells on dextran sodium sulfate (DSS)-induced inflammatory bowel disease (IBD) rats. Four groups of rats ( n = 12 per group) were included: normal control, DSS-induced colitis rats without bacterial administration (DSS), DSS-induced colitis rats with viable B. infantis B8762 administration (VB8762), and
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