Academic literature on the topic 'Biofluid mechanics'

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Journal articles on the topic "Biofluid mechanics"

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Skalak, R., N. Ozkaya, and T. C. Skalak. "Biofluid Mechanics." Annual Review of Fluid Mechanics 21, no. 1 (1989): 167–200. http://dx.doi.org/10.1146/annurev.fl.21.010189.001123.

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Rajesh, Parvati. "Cardiovascular Biofluid Mechanics." International Journal of Innovative Science and Research Technology 5, no. 7 (2020): 36–39. http://dx.doi.org/10.38124/ijisrt20jul186.

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This paper intends to study a real-life application of fluid mechanics in cardiovascular blood flow. The study of blood flow is termed as Hemodynamics. Fluid mechanics can be used to analyze the factors and impact of obstruction in blood flow due to fat, cholesterol, and plaque deposits in the coronary arteries of the human heart. These blockages are the grounds for coronary artery diseases and heart attacks. We will look at varying parameters of flowrate and pressure for different thicknesses of epicardial fat as well as define a relationship between these three.
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Schneek, Daniel J., and Carol L. Lucas. "Biofluid Mechanics 3." Journal of Clinical Engineering 17, no. 1 (1992): 33. http://dx.doi.org/10.1097/00004669-199201000-00015.

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Grotberg, James B. "Preface: Biofluid mechanics." Physics of Fluids 17, no. 3 (2005): 031401. http://dx.doi.org/10.1063/1.1862617.

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Liepsch, D. "Biofluid Mechanics. Biofluidmechanik." Biomedizinische Technik/Biomedical Engineering 43, no. 4 (1998): 94–99. http://dx.doi.org/10.1515/bmte.1998.43.4.94.

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Reddy, Narender P., and Sunil K. Kesavan. "Perspectives in Non-Traditional Biofluid Mechanics." Engineering in Medicine 16, no. 1 (1987): 43–45. http://dx.doi.org/10.1243/emed_jour_1987_016_010_02.

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Although biofluid mechanics has been studied extensively, most of the studies have concentrated on cardiovascular biofluid mechanics. Very little attention has been paid to the other important problems in biomedicine. Several non-traditional areas which offer interesting and challenging problems remain unexplored, and fluid mechanics can have fruitful interaction with these disciplines. This paper brings into focus some of the important areas of biomedicine which offer fertile grounds for biofluid mechanics studies.
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Elad, David, and Danny Bluestein. "Biofluid mechanics: innovations and challenges." Journal of Biomechanics 46, no. 2 (2013): 207. http://dx.doi.org/10.1016/j.jbiomech.2012.11.034.

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Grotberg, James B., and Oliver E. Jensen. "BIOFLUID MECHANICS IN FLEXIBLE TUBES." Annual Review of Fluid Mechanics 36, no. 1 (2004): 121–47. http://dx.doi.org/10.1146/annurev.fluid.36.050802.121918.

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Verdonck, Pascal, and Kris Dumont. "Biofluid mechanics and the circulatory system." Technology and Health Care 19, no. 3 (2011): 205–15. http://dx.doi.org/10.3233/thc-2011-0623.

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Bertram, Chris D., and Donald P. Gaver. "Biofluid Mechanics of the Pulmonary System." Annals of Biomedical Engineering 33, no. 12 (2005): 1681–88. http://dx.doi.org/10.1007/s10439-005-8758-0.

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Dissertations / Theses on the topic "Biofluid mechanics"

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Bruckner, Michael. "Biofluid Mechanics Of Embryo Transfer." Thesis, Lyon 1, 2013. http://www.theses.fr/2013LYO10159.

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Cette thèse porte sur l'étude du comportement hydrodynamique d'un embryon lors de la procédure de transfert suivant la fécondation in-vitro. Un couple sur six fait l'expérience de problèmes d'infertilité. Aujourd'hui 5 millions de nourrissons sont nés depuis la première fécondation in-vitro en 1978. En 2009, 1.5 millions de cycles de Procréation Médicalement Assistée étaient débutés, donnant ainsi naissance à350 000 nourrissons de par le monde. Le nombre de cycle est en constante augmentation de 5 à 10 % par an et le nombre de cycle de PMA pourrait être proche de 4 millions à l'horizon 2020. Bien que l'étape de fertilisation soit maintenant bien maitrisée avec 80% de réussite, l'étape finale du transfert d'embryon dans la cavité intra-utérine reste une étape critique puisque seulement 25% des cycles mènent à une grossesse viable. Bien que chaque cycle soit couteux, aucun protocole spécifique, optimisé, et indépendant de l'opérateur n'a encore été mis au point. Dans cette thèse, nous nous proposons de démontrer dans un premier temps l'intérêt et la faisabilité d'une approche de bio ingénierie. En effet, bien que l'issue de transfert dépende de nombreux facteurs chimiques et physiologiques, cette étape cruciale peut aussi être étudiée d'un point de vue mécanique des fluides. Cette étape peut être décomposée en plusieurs sous-étapes : l'introduction du cathéter dans la cavité intra utérine, l'injection du fluide medium contenant un ou plusieurs embryons, et le retrait du cathéter. On peut dégager plusieurs paramètres d'importance comme la viscosité des fluides, la vitesse d'injection, la vitesse de retrait du cathéter, le schéma de chargement du cathéter, et les géométries de la cavité et du cathéter. Dans une deuxième partie, nous nous intéressons à la structure des écoulements de fluides intra-uterins au moment de l'injection. L'influence des paramètres constitutifs d'importance est étudiée grâce à un code de calcul résolvant les équations de Navier-Stokes dans une géométrie tri-dimensionnelle idéalisée. Une étude des trajectographies potentielles des embryons est également réalisée et mis en relation directe avec les zones d'implantation optimales et à risques. A l'issue de ces calculs, nous sommes en mesure de proposer des recommandations à l'usage des cliniciens pratiquant le transfert d'embryon. La dernière partie de la thèse est une ouverture vers les méthodes numériquesnécessaires à l'appréhension des phénomènes d'interaction fluide/structure à l'échelle de l'embryon. L'embryon est en effet soumis à des contraintes potentiellement destructrices au moment du transfert qu'il ne nous est pas possible de définir précisément _à l'_échelle de l'utérus. Dans l'optique du développement d'un modèle mécanique d'un blastocyste pour déterminer les paramètres procéduraux minimisant les contraintes, nous présentons l'implémentation de deux méthodes numériques de type Eulerienne-Eulerienne. La première est une méthode level-set dans un code en volumes finis et bénéficiant de raffinement de maillage automatique. La seconde concerne une méthode phase-field basée sur un formalisme éléments finis de type Galerkin discontinu<br>This thesis focuses on the study of the hydrodynamic behavior of an embryo during the transfer process following the in vitro fertilization. Worldwide, one in six couples experiences infertility problems. Today, 5 millions babies are born from an in-vitro fertilization since the first one in 1978. In 2009, 1.5 millions Assisted Reproductive Technology cycles have been started, resulting in 350 000 births. The total number of cycles per year is constantly increasing (from 5 to 10 %), and the number of ART cycles is believed to reach 4 millions per year in 2020. Although the fertilization step is now fairly mastered with a 80% success rate, the final stage consisting in the embryo transfer into the uterine cavity remains a critical step, since only 25% of the cycles lead to a live birth. Even though every cycle is expensive, no specific, optimized and operator-independent protocol has been developed yet. In this thesis, we first demonstrate the interest and the feasibility of a bio-engineering approach. Indeed, although the issue of the transfer depends on numerous chemical and physiological factors, this crucial step can also be studied from a fluid mechanical point of view. This step can be divided in several sub-steps : introduction of the catheter in the intra-uterine cavity, injection of the medium fluid containing one or several embryos, and the withdrawal of the catheter. One can identify several important parameters such as fluids viscosity, injections speeds, catheter withdrawal speed, catheter loading scheme and the geometries of the uterine cavity and the catheter. In a second part, we focus on the fluid ow patterns inside the uterine cavity during the injection. The influence of the system parameters is studied thanks to a computational solving of the Navier-Stokes equations in an idealized three-dimensional uterine cavity. A study of the potential trajectories of the embryos is also conducted and confronted against the location of optimal implantation zones but also risky zones. As the outcome of these computations, we are able to propose recommendations for physicians practicing embryo transfers. In the last part of the thesis, we discuss numerical methods for the fluid{structure interaction study of embryo transfer. The embryo is indeed submitted to potentially destructive stress constraints at injection time that we are not capable of defining precisely at the scale of the uterine cavity. With the aim of developing a mechanical model for the blastocyst to determine system parameters minimizing the constraints, we present the implementation of two Eulerian numerical methods. The first one is a fluid-structure level set method in a finite volume code benefiting from an automatic mesh refinement feature. The second one addresses a phase field method based on a Discontinuous Galerkin finite element formalism
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Biglino, Giovanni. "Experimental study of the mechanics of the intra-aortic balloon." Thesis, Brunel University, 2010. http://bura.brunel.ac.uk/handle/2438/4510.

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This thesis deals with the mechanics of the Intra-Aortic Balloon Pump (IABP), the most widely used temporary cardiac assist device, whose beneficial action is based on the principle of counterpulsation. The investigation is carried out in vitro in increasingly more realistic setups, including a mock circulatory system with physiological distribution of peripheral resistance and compliance in which IABP counterpulsation was simulated. Pressure and flow measurements show the effect of variables such as intra-luminal pressure, angle and aortic compliance on balloon hemodynamics. These data are complemented by results on the duration of balloon inflation and deflation obtained by means of high-speed camera visualisation. Furthermore, wave intensity analysis is carried out and it is identified as a possible alternative method for the assessment of IABP performance. This work includes two prototypes of intra-aortic balloons of novel shape with the balloon chamber tapering both from and toward the balloon tip. In clinical terms, with reference to the semi-recumbent position in which patients assisted with the IABP are nursed in the intensive care unit, the results presented in this thesis indicate that operating the balloon at an angle compromises the benefit of counterpulsation when assessed in vitro.
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Comerford, Andrew Peter. "Computational Models of Endothelial and Nucleotide Function." Thesis, University of Canterbury. Mechanical Engineering, 2007. http://hdl.handle.net/10092/1178.

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Atherogenesis is the leading cause of death in the developed world, and is putting considerable monetary pressure on health systems the world over. Although the risk factors are well understood, unfortunately, the initiation and development of this disease still remains relatively poorly understood, but it is becoming increasingly identifiable as a dysfunction of the endothelial cells that line the walls of arteries. The prevailing haemodynamic environment plays an important role in the focal nature of atherosclerosis to very specific regions of the human vasculature. Disturbed haemodynamics lead to very low wall shear stress, and inhibit the transport of important blood borne chemicals. The present study models, both computationally and mathematically, the transport and hydrolysis of important blood borne adneosine nucleotides in physiologically relevant arterial geometries. In depth analysis into the factors that affect the transport of these low diffusion coefficient species is undertaken. A mathematical model of the complex underlying endothelial cell dynamics is utilised to model production of key intracellular molecules that have been implicated into the complex initiation processes of atherosclerosis; hence regions of the vasculature can be identified as being 'hot spots' for atherogenesis. This model is linked into CFD software allowing for the assessment of how 3D low yields and mass transfer affect the underlying cell signalling. Three studies are undertaken to further understand nucleotide variations at the endothelium and to understand factors involved in determining the underlying cell dynamics. The major focus of the first two studies is geometric variations. This is primarily due to the plethora of evidence implicating the geometry of the human vasculature, hence the haemodynamics, as an influential factor in atherosclerosis initiation. The final model looks at a physiologically realistic geometry to provide a more realistic reproduction of the in vivo environment.
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Gadelha, Hermes. "Mathematical modelling of human sperm motility." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:34a11669-5d14-470b-b10b-361cf3688a30.

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The propulsion mechanics driving the movement of living cells constitutes one of the most incredible engineering works of nature. Active cell motility via the controlled movement of a flagellum beating is among the phylogentically oldest forms of motility, and has been retained in higher level organisms for spermatozoa transport. Despite this ubiquity and importance, the details of how each structural component within the flagellum is orchestrated to generate bending waves, or even the elastic material response from the sperm flagellum, is far from fully understood. By using microbiomechanical modelling and simulation, we develop bio-inspired mathematical models to allow the exploration of sperm motility and the material response of the sperm flagellum. We successfully construct a simple biomathematical model for the human sperm movement by taking into account the sperm cell and its interaction with surrounding fluid, through resistive-force theory, in addition to the geometrically non-linear response of the flagellum elastic structure. When the surrounding fluid is viscous enough, the model predicts that the sperm flagellum may buckle, leading to profound changes in both the waveforms and the swimming cell trajectories. Furthermore, we show that the tapering of the ultrastructural components found in mammalian spermatozoa is essential for sperm migration in high viscosity medium. By reinforcing the flagellum in regions where high tension is expected this flagellar accessory complex is able to prevent tension-driven elastic instabilities that compromise the spermatozoa progressive motility. We equally construct a mathematical model to describe the structural effect of passive link proteins found in flagellar axonemes, providing, for the first time, an explicit mathematical demonstration of the counterbend phenomenon as a generic property of the axoneme, or any cross-linked filament bundle. Furthermore, we analyse the differences between the elastic cross-link shear and pure material shear resistance. We show that pure material shearing effects from Cosserat rod theory or, equivalently, Timoshenko beam theory or are fundamentally different from elastic cross-link induced shear found in filament bundles, such as the axoneme. Finally, we demonstrate that mechanics and modelling can be utilised to evaluate bulk material properties, such as bending stiffness, shear modulus and interfilament sliding resistance from flagellar axonemes its constituent elements, such as microtubules.
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Gentile, Russell. "Adding cerebral autoregulation to a lumped parameter model of blood flow." Honors in the Major Thesis, University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/555.

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A mathematical model of blood flow in infants with hypoplastic left heart syndrome (HLHS) was improved by adding cerebral autoregulation. This is the process by which blood vessels constrict or dilate to keep blood flow steady in certain organs during pressure changes. The original lumped parameter model transformed the fluid flow into an electrical circuit. Its behavior is described using a system of thirty-three coupled differential equations that are solved numerically using a fourth-order Runge-Kutta method implemented in MATLAB. A literature review that includes a discussion of autoregulation mechanisms and approaches to modeling them is followed by a description of the model created for this paper. The model is based on the baroreceptor or neurogenic theory of autoregulation. According to this theory, nerves in certain places within the cardiovascular system detect changes in blood pressure. The brain then compensates by sending a signal to blood vessels to constrict or dilate. The model of the control system responded fairly well to a pressure drop with a steady state error of about two percent. Running the model with or without the control system activated had little effect on other parameters, notably cardiac output. A more complete model of blood flow control would include autonomic regulation. This would vary more parameters than local autoregulation, including heart rate and contractility. This is suggested as a topic of further research.<br>B.S.M.E.<br>Bachelors<br>Engineering and Computer Science<br>Mechanical Engineering
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Fellman, Batya A. (Batya Ayala). "A study of a flapping flag in viscoelastic fluids and its implications for micro-scale swimming in biofluids." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/45795.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2008.<br>Includes bibliographical references (leaf 37).<br>Biological cells and organisms employ a different method of propulsion when in viscous, viscolelastic fluids rather than Newtonian fluids. By studying the dynamics of a flag under a flow of a viscoelastic fluid, we hope to better understand the swimming dynamics in these biological fluids. A slender polysiloxane rod was placed in a rotating annulus filled with a cetyl pyridnium chloride micellar solution and also with a xanthan gum solution. Flapping of the rod was observed with the micellar solution for Weissenberg numbers greater than 1, where elastic forces in the fluid dominated the elastic force in the flag. Flapping was not observed in the xanthan gum for Weissenberg numbers up to 250, where the elastic force in the flag dominated the elastic force in the fluid. The observation of a flapping flag in a viscoelastic fluid indicates that, unlike in a Newtonian fluid, the polymers in the fluid can interact with an elastic body to cause a flapping motion which may indicate why the swimming dynamics of sperm change with their fluid environment.<br>by Batya A. Fellman.<br>S.B.
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Khaled, Abdul Rahim Assaad Mr. "Non-isothermal characterization of squeezed thin films in the presence of biofluids and suspended ultrafine particles." The Ohio State University, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=osu1071085983.

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Lind, Anne-Li. "Biomarkers for Better Understanding of the Pathophysiology and Treatment of Chronic Pain : Investigations of Human Biofluids." Doctoral thesis, Uppsala universitet, Anestesiologi och intensivvård, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-326180.

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Chronic pain affects 20 % of the global population, causes suffering, is difficult to treat, and constitutes a large economic burden for society. So far, the characterization of molecular mechanisms of chronic pain-like behaviors in animal models has not translated into effective treatments. In this thesis, consisting of five studies, pain patient biofluids were analyzed with modern proteomic methods to identify biomarker candidates that can be used to improve our understanding of the pathophysiology chronic pain and lead to more effective treatments. Paper I is a proof of concept study, where a multiplex solid phase-proximity ligation assay (SP-PLA) was applied to cerebrospinal fluid (CSF) for the first time. CSF reference protein levels and four biomarker candidates for ALS were presented. The investigated proteins were not altered by spinal cord stimulation (SCS) treatment for neuropathic pain. In Paper II, patient CSF was explored by dimethyl and label-free mass spectrometric (MS) proteomic methods. Twelve proteins, known for their roles in neuroprotection, nociceptive signaling, immune regulation, and synaptic plasticity, were identified to be associated with SCS treatment of neuropathic pain. In Paper III, proximity extension assay (PEA) was used to analyze levels of 92 proteins in serum from patients one year after painful disc herniation. Patients with residual pain had significantly higher serum levels of 41 inflammatory proteins. In Paper IV, levels of 55 proteins were analyzed by a 100-plex antibody suspension bead array (ASBA) in CSF samples from two neuropathic pain patient cohorts, one cohort of fibromyalgia patients and two control cohorts. CSF protein profiles consisting of levels of apolipoprotein C1, ectonucleotide pyrophosphatase/phosphodiesterase family member 2, angiotensinogen, prostaglandin-H2 D-isomerase, neurexin-1, superoxide dismutases 1 and 3 were found to be associated with neuropathic pain and fibromyalgia. In Paper V, higher CSF levels of five chemokines and LAPTGF-beta-1were detected in two patient cohorts with neuropathic pain compared with healthy controls. In conclusion, we demonstrate that combining MS proteomic and multiplex antibody-based methods for analysis of patient biofluid samples is a viable approach for discovery of biomarker candidates for the pathophysiology and treatment of chronic pain. Several biomarker candidates possibly reflecting systemic inflammation, lipid metabolism, and neuroinflammation in different pain conditions were identified for further investigation.<br>Uppsala Berzelii Technology Centre for Neurodiagnostics
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Čapek, Marek. "Matematické modelování procesu koagulace krve." Doctoral thesis, 2019. http://www.nusl.cz/ntk/nusl-404579.

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On vessel wall injury the complex process of blood coagulation is set off. It is composed of vasoconstriction, primary hemostasis, secondary hemostasis and fibrinolysis. This work enriches current model of primary hemostasis of Storti. The previous model used ALE formalism for tracing of development of platelet plug. The phase field method is used for tracing of the development of interface blood-thrombus. Storti's primary hemostasis was extended to capture the fact, that the platelets can be activated in the blood flow in the area of reactive surface not only by influence of chemical agents like thromboxane, ADP and thrombin but also by their exposure to elevated values of shear stress. In our first approach we deal the emerging thrombus as a fluid with very high viscosity. In the second approach it was assumed, that platelet plug develops as a viscoelastic material according to constitutive equations of clot introduced by Kempen. In this manner platelet clot matures into blood clot. In both approaches the blood is represented as a non-Newtonian fluid. The framework of the phase field method was applied also to the model of high shear rate thrombosis of Weller. Weller's original model of Weller took advantage of the cylindrical symmetry of computational domains for its computations, hence the...
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Usha, S. "Peristaltic Transport Of Biofluids." Thesis, 1995. https://etd.iisc.ac.in/handle/2005/1735.

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Books on the topic "Biofluid mechanics"

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Liepsch, Dieter W., ed. Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0.

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J, Schneck Daniel, Lucas Carol L. 1940-, and Biomedical Engineering Society. Fall Meeting, eds. Biofluid mechanics, 3. New York University Press, 1990.

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Chen, Po-Yuan. The Application of Biofluid Mechanics. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-44952-9.

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Yoganathan, A. P. (Ajit Prithiviraj), 1951- and Rittgers Stanley E. 1947-, eds. Biofluid mechanics: The human circulation. 2nd ed. Taylor & Francis, 2012.

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Chandran, K. B. Biofluid mechanics: The human circulation. 2nd ed. Taylor & Francis, 2012.

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Waite, Lee. Biofluid mechanics in cardiovascular systems. McGraw-Hill, 2006.

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1947-, Rittgers Stanley E., and Yoganathan A. P. 1951-, eds. Biofluid mechanics: The human circulation. CRC/Taylor & Francis, 2007.

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Rubenstein, David A. Biofluid mechanics: An introduction to fluid mechanics, macrocirculation, and microcirculation. Elsevier Academic Press, 2012.

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Dieter, Liepsch, and American Society of Mechanical Engineers., eds. Biofluid mechanics: Blood flow in large vessels : proceedings of the 2nd International Symposium Biofluid Mechanics and Biorheology, June 25-28, 1989, Munich. Springer-Verlag, 1990.

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Goyal, Megh Raj. Biofluid dynamics of human body systems. Apple Academic Press, 2014.

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Book chapters on the topic "Biofluid mechanics"

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Oertel, Herbert. "Biofluid Mechanics." In Applied Mathematical Sciences. Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1564-1_12.

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Stehbens, W. E., and B. J. Martin. "Hemodynamically Induced Atrophic Lesions of Atherosclerosis." In Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0_1.

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Tanio, Hitoshi, Toshiaki Kumada, Yasuki Kihara, et al. "Direct Measurement of Aortic and Vena Caval Flow to Evaluate the Effect of Vasodilators in Experimental Acute mitral regurgitation." In Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0_10.

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Gieseking, Elizabeth R., Xavier P. Lefebvre, Edward G. Cape, Robert A. Levine, and Ajit P. Yoganathan. "Echocardiographic and Flow Visualization Studies of the Mechanism for Systolic Anterior Motion of the Mitral Valve In Hypertrophic Cardiomyopathy." In Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0_11.

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Jones, C. J. H., and C. G. Caro. "The Potential Importance of Arterial Wall Properties and Blood Flow in Relation to Atherogenesis in Essential Hypertension." In Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0_12.

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Marshall, M. "Reliability and Problems of Doppler-Sonography in the Assessment of Carotid Stenoses." In Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0_13.

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Preissler, H., K. Paulat, A. Giebler, and H. Bressmer. "The On-line Assessment of Blood Flow Characteristics During Cerebro-vascular Examinations." In Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0_14.

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Sugawara, Motoaki, Akio Hirai, Yasutsugu Seo, Yasuo Miyajima, and Takanobu Uchibori. "A Method of Measuring the Peak Flow-Rate and the Regurgitant Volume of Regurgitation." In Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0_15.

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Lucas, Carol L., William Henry, Belinda Ha, Jose I. Ferreiro, Elman G. Frantz, and Benson R. Wilcox. "Characterization of Pulmonary Artery Blood Velocity Patterns in Lambs." In Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0_16.

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Ludwig, M. "Detection of Very Early Atherosclerosis by Duplex Sonography." In Biofluid Mechanics. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-52338-0_17.

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Conference papers on the topic "Biofluid mechanics"

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Shi, W. P., D. L. Ding, Jiachun Li, and Song Fu. "Biofluid Flow Simulations of Embryo Transfer." In RECENT PROGRESSES IN FLUID DYNAMICS RESEARCH: Proceeding of the Sixth International Conference on Fluid Mechanics. AIP, 2011. http://dx.doi.org/10.1063/1.3651955.

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Liu, Kunlun, and Victor H. Barocas. "The Dynamic Simulation of Flow Through a Tissue Engineered Bileaflet Heart Valve." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193075.

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Approximately 250,000 patients diagnosed with valvular heart disease undergo valve repair/replacement surgery annually worldwide [1, 2]. Despite being over 50 years old, heart valve replacement technology, with the choice of mechanical or bioprosthetic, remains imperfect. The 10-year mortality rate after replacement is 30–55%, with reoperation rates of 2–4% per year because of mechanical failure, bleeding and thromboembolic complications, and calcification. It is therefore imperative that design and analysis tools be developed for the biosolid and biofluid mechanics of potential replacement valves.
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Schaller, Jens, and Leonid Goubergrits. "CFD Challenge: Solutions Using the Commercial Finite Volume Solver, Fluent." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80276.

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The Biofluid Mechanics Laboratory is working on hemodyanamics of medical devices and vessels — carotid bifurcations, coronary arteries and cerebral aneurysms — since mid 90s. For this challenge the simulations were performed by the doctorate student Jens Schaller supported by the student coworker Jan Osman using the commercial solver Fluent (Fluent 6.3.26, Ansys Inc., Canonsburg, USA).
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4

Goubergrits, L., R. Mevert, P. Yevtushenko, et al. "Treatment of the Aortic Coarctation: Prediction of the Hemodynamic Impact." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14397.

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Aortic coarctation (CoA) accounts for approximately 10% of congenital heart diseases 1. CoA causing high pressure gradient can be successfully treated surgical or catheter-based. Long-term results, however, revealed decreased life expectancy associated with abnormal hemodynamics 1. To develop a next-generation personalized diagnostic-prognostic tools allowing treatment optimization and thus to improve life expectance, the innovative combination of imaging science, biofluid mechanics, and computer modeling is necessary. Patient-specific computational fluid dynamics (CFD) models of the CoA based on MRI data were created to analyze pre- and post-treatment hemodynamics with a focus on pressure gradient.
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Baek, Seungik, C. Alberto Figueroa, Charles A. Taylor, and Jay D. Humphrey. "A Framework for Fluid-Solid-Growth Modeling and its Application to Understanding the Enlargement of a Fusiform Aneurysm." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192805.

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Blood vessels adapt in response to changes in their biomechanical and biochemical environment under various physiological and pathological conditions. While advances in computational hemodynamics and arterial wall mechanics have been spectacular, such advances have been achieved separately; there is, therefore, a pressing need for coupling biosolid and biofluid mechanics within a computationally efficient framework to study effects of fluid-solid interactions (FSI) in growth and remodeling (G&amp;R) of the vessel wall. Toward this end, we built a fluid-solid-growth (FSG) modeling framework [1] that incorporates four separate advances by our groups: biomechanics of G&amp;R [2], a coupled momentum method for FSI during a cardiac cycle [3], a theory of small on large for coupling G&amp;R and FSI models [4], and improved approaches for modeling fluid boundary conditions in complex vascular systems [5]. Although the framework presented here is sufficiently general to apply to many different vascular adaptation problems, we first apply this framework to a fusiform aneurysm with a simple geometry.
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Sheidaei, A., S. C. Hunley, L. G. Raguin, and S. Baek. "Simulation of Aneurysm Growth With Stepwise Updating of Hemodynamic Loads Using an MRI-Based Geometric Model." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-205499.

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Computer simulations of vascular tissue adaptation under various physiological and pathological conditions have emerged as a new area of research and aided researchers in their understanding of stress-mediated growth and remodeling (G&amp;R) in these structures. With advances in computational biomechanics and biomedical imaging techniques, combinations of these advanced methods will provide promising tools for medical diagnosis and surgical planning in the future (e.g., [1]). Recently Figueroa et al. [2] presented a new computational framework that brings advances in computational biosolid and biofluid mechanics together in order to exploit new information on the biology of vascular growth and remodeling (G&amp;R). Although the framework presented in their paper was generalized for simplicity, they did illustrate the effectiveness of this framework by applying it to a fusiform aneurysm growth with idealized geometry. In the present work, we employ this framework and test it on an anatomically realistic model of abdominal aortic aneurysm (AAA) growth. Similarly to Figueroa et al., when the stress-mediated kinetics only depends on intramural stress, the shape of the aneurysm and the expansion rate are similar to the results from the computation without using an iterative loop. However, we expect that when the stress-mediated kinetics depends on either shear or other hemodynamic components, the evolution of an AAA can change significantly.
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Xue, Xiangdong, Mayur K. Patel, Maiwenn Kersaudy-Kerhoas, Chris Bailey, Marc P. Y. Desmulliez, and David Topham. "Effect of fluid dynamics and device mechanism on biofluid behaviour in microchannel systems: Modelling biofluids in a microchannel biochip separator." In High Density Packaging (ICEPT-HDP). IEEE, 2009. http://dx.doi.org/10.1109/icept.2009.5270767.

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Kee, Daniel De, and Ning Sun. "Modeling Flow Properties in Biofluids." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-1938.

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Abstract Biofluids such as blood, as well as other structured materials, exhibit rather complex rheological behavior. In this paper, starting from a first order kinetic model introduced by Soong et al., we developed a constitutive equation and studied its applicability to model biofluids. In particular, we studied the cases of steady shear flow, hysteresis, yield stress and small amplitude oscillatory flow. Model predictions were successfully compared with experimental data on complex materials such as blood and a penicillin suspension.
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Zhang, Jian, Zhe Sun, Xiujun Wang, and Xiaodong Kang. "Study on the Oil Displacement Effect and Application of Soft Microgel Flooding Technology." In SPE Middle East Oil & Gas Show and Conference. SPE, 2021. http://dx.doi.org/10.2118/204764-ms.

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Abstract Due to the reservoir heterogeneity, there is still a lot of remaining oil that cannot be displaced by water flooding. Therefore, taking the whole injection-production flow field as the research object, the dominant channel is divided into macro and micro channel. Then the corresponding oil displacement system is adopted to realize the continuous flow diversion and effective expansion of swept volume. For micro channels, the soft microgel particle dispersion can be used. It is a novel flooding system developed in recent years. Due to its excellent performance and advanced mechanism, the oil recovery rate can be greatly improved. Soft microgel particle dispersion consists of microgel particles and its carrier fluid. After coming into porous media, its unique phenomenon of particle phase separation appears, which leads to the properties of "plugging large pore and leave the small one open", and the deformation and migration characteristic in the poros media. Therefore, particle phase separation of soft microgel particle dispersion is studied by using the microfluidic technology and numerical simulation. On this basis, by adopting the NMR and 3D Printing technology, the research on its oil displacement mechanism is further carried out. Furthermore, the typical field application cases are analyzed. Results show that, soft microgel particles have good performance and transport ability in porous media. According to the core displacement experiment, this paper presents the matching coefficient between microgels and pore throat under effective plugging modes. Also, the particle phase separation happens when injecting microgels into the core, which makes the particles enter the large pore in the high permeability layer and fluid enters into small pore. Therefore, working in cooperation, this causes no damage to the low permeability layer. On this basis, theoretically guided by biofluid mechanics, the mathematical model of soft microgel particle is established to simulate its concentration distribution, which obtained the quantitative research results. Furthermore, the micro displacement experiment shows that, microgels has unique deformation and migration characteristic in the poros media, which can greatly expand swept volume. The macro displacement experiment shows that, microgels have good oil displacement performance. Finally, the soft microgel particle dispersion flooding technology has been applied in different oilfields since 2007. Results show that these field trials all obtain great oil increasing effect, with the input-output ratio range of 2.33-14.37. And two field application examples are further introduced. Through interdisciplinary innovative research methods, the oil displacement effect and field application of soft microgel particle dispersion is researched, which proves its progressiveness and superiority. The research results play an important role in promoting the application of this technology.
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Pourshaban, Erfan, Adwait Deshpande, Mohit U. Karkhanis, et al. "A Micro-Fabricated Aluminum-Air Moving Biofluid Battery For Medical Wearables." In 2022 IEEE 35th International Conference on Micro Electro Mechanical Systems Conference (MEMS). IEEE, 2022. http://dx.doi.org/10.1109/mems51670.2022.9699832.

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