Journal articles: 'Biofluid mechanics'

1

Skalak, R., N. Ozkaya, and T. C. Skalak. "Biofluid Mechanics." Annual Review of Fluid Mechanics 21, no. 1 (1989): 167–200. http://dx.doi.org/10.1146/annurev.fl.21.010189.001123.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Rajesh, Parvati. "Cardiovascular Biofluid Mechanics." International Journal of Innovative Science and Research Technology 5, no. 7 (2020): 36–39. http://dx.doi.org/10.38124/ijisrt20jul186.

Full text

Abstract:

This paper intends to study a real-life application of fluid mechanics in cardiovascular blood flow. The study of blood flow is termed as Hemodynamics. Fluid mechanics can be used to analyze the factors and impact of obstruction in blood flow due to fat, cholesterol, and plaque deposits in the coronary arteries of the human heart. These blockages are the grounds for coronary artery diseases and heart attacks. We will look at varying parameters of flowrate and pressure for different thicknesses of epicardial fat as well as define a relationship between these three.

APA, Harvard, Vancouver, ISO, and other styles

3

Schneek, Daniel J., and Carol L. Lucas. "Biofluid Mechanics 3." Journal of Clinical Engineering 17, no. 1 (1992): 33. http://dx.doi.org/10.1097/00004669-199201000-00015.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Grotberg, James B. "Preface: Biofluid mechanics." Physics of Fluids 17, no. 3 (2005): 031401. http://dx.doi.org/10.1063/1.1862617.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Liepsch, D. "Biofluid Mechanics. Biofluidmechanik." Biomedizinische Technik/Biomedical Engineering 43, no. 4 (1998): 94–99. http://dx.doi.org/10.1515/bmte.1998.43.4.94.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Reddy, Narender P., and Sunil K. Kesavan. "Perspectives in Non-Traditional Biofluid Mechanics." Engineering in Medicine 16, no. 1 (1987): 43–45. http://dx.doi.org/10.1243/emed_jour_1987_016_010_02.

Full text

Abstract:

Although biofluid mechanics has been studied extensively, most of the studies have concentrated on cardiovascular biofluid mechanics. Very little attention has been paid to the other important problems in biomedicine. Several non-traditional areas which offer interesting and challenging problems remain unexplored, and fluid mechanics can have fruitful interaction with these disciplines. This paper brings into focus some of the important areas of biomedicine which offer fertile grounds for biofluid mechanics studies.

APA, Harvard, Vancouver, ISO, and other styles

7

Elad, David, and Danny Bluestein. "Biofluid mechanics: innovations and challenges." Journal of Biomechanics 46, no. 2 (2013): 207. http://dx.doi.org/10.1016/j.jbiomech.2012.11.034.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Grotberg, James B., and Oliver E. Jensen. "BIOFLUID MECHANICS IN FLEXIBLE TUBES." Annual Review of Fluid Mechanics 36, no. 1 (2004): 121–47. http://dx.doi.org/10.1146/annurev.fluid.36.050802.121918.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Verdonck, Pascal, and Kris Dumont. "Biofluid mechanics and the circulatory system." Technology and Health Care 19, no. 3 (2011): 205–15. http://dx.doi.org/10.3233/thc-2011-0623.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Bertram, Chris D., and Donald P. Gaver. "Biofluid Mechanics of the Pulmonary System." Annals of Biomedical Engineering 33, no. 12 (2005): 1681–88. http://dx.doi.org/10.1007/s10439-005-8758-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Liepsch, Dieter. "International Symposium on Biofluid Mechanics and Biorheology." Clinical Hemorheology and Microcirculation 10, no. 1 (2016): 119–36. http://dx.doi.org/10.3233/ch-1990-10113.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Johnson, Greg A., David A. Vorp, and Harvey S. Borovetz. "Biofluid mechanics—Blood flow in larger vessels." Journal of Biomechanics 25, no. 2 (1992): 211. http://dx.doi.org/10.1016/0021-9290(92)90279-a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Manning, Keefe B. "Biofluid Mechanics: The Human Circulation (second edition)." Cardiovascular Engineering and Technology 3, no. 4 (2012): 351–52. http://dx.doi.org/10.1007/s13239-012-0106-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Nithiarasu, P. "Special issue on biofluid dynamics." International Journal for Numerical Methods in Fluids 57, no. 5 (2008): 473–74. http://dx.doi.org/10.1002/fld.1849.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Verdonck, Pascal. "Impact of Biofluid Mechanics on Vascular Access Research." Artificial Organs 28, no. 7 (2004): 601–3. http://dx.doi.org/10.1111/j.1525-1594.2004.01042.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Liepsch, Dieter. "Biofluid mechanics – an interdisciplinary research area of the future." Technology and Health Care 14, no. 4-5 (2006): 209–14. http://dx.doi.org/10.3233/thc-2006-144-503.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

L. Faria, Carlos, Diana Pinho, Jorge Santos, Luís M. Gonçalves, and Rui Lima. "Low cost 3D printed biomodels for biofluid mechanics applications." Journal of Mechanical Engineering and Biomechanics 3, no. 1 (2018): 1–7. http://dx.doi.org/10.24243/jmeb/3.1.166.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Liepsch, D. "What role do biofluid mechanics play in health care?" Journal of Biomechanics 39 (January 2006): S302—S303. http://dx.doi.org/10.1016/s0021-9290(06)84179-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Liepsch, Dieter. "An introduction to biofluid mechanics—basic models and applications." Journal of Biomechanics 35, no. 4 (2002): 415–35. http://dx.doi.org/10.1016/s0021-9290(01)00185-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Einav, Shmuel, David Elad, C. Ross Ethier, and Morteza Gharib. "International Biofluid Mechanics Symposium: Position Papers and Key Challenges." Annals of Biomedical Engineering 33, no. 12 (2005): 1673. http://dx.doi.org/10.1007/s10439-005-8756-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Sattari, Amirmohammad. "Machine learning in biofluid mechanics: A review of recent developments." Computers in Biology and Medicine 193 (July 2025): 110410. https://doi.org/10.1016/j.compbiomed.2025.110410.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Zamir, Mair, James E. Moore, Hideki Fujioka, and Donald P. Gaver. "Biofluid Mechanics of Special Organs and the Issue of System Control." Annals of Biomedical Engineering 38, no. 3 (2010): 1204–15. http://dx.doi.org/10.1007/s10439-010-9902-z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Hill, N. A. "Biofluid Mechanics. By J. N. Mazumdar. World Scientific, 1992. 191 pp. $35." Journal of Fluid Mechanics 270 (July 10, 1994): 377. http://dx.doi.org/10.1017/s002211209422431x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Einav, Shmuel, Danny Bluestein, and Oren M. Rotman. "Special issue on "Biofluid mechanics of multitude pathways: From cellular to organ"." Journal of Biomechanics 50 (January 2017): 1–2. http://dx.doi.org/10.1016/j.jbiomech.2016.12.010.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Begum, Fathimunnisa, N. Ravi Kumar, and V. Ramachandra Raju. "Tribological Experimentations with Jatropha Biofluid and Nanoparticles as Lubricant Additives." Transactions of FAMENA 46, no. 3 (2022): 41–50. http://dx.doi.org/10.21278/tof.463024920.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Lin, Jia-Yun, Chi-Hao Zhang, Lei Zheng, et al. "Establishment and assessment of the hepatic venous pressure gradient using biofluid mechanics (HVPGBFM): protocol for a prospective, randomised, non-controlled, multicentre study." BMJ Open 9, no. 12 (2019): e028518. http://dx.doi.org/10.1136/bmjopen-2018-028518.

Full text

Abstract:

IntroductionPortal hypertension (PH) is a severe disease with a poor outcome. Hepatic venous pressure gradient (HVPG), the current gold standard to detect PH, is available only in few hospitals due to its invasiveness and technical difficulty. This study aimed to establish and assess a novel model to calculate HVPG based on biofluid mechanics.Methods and analysisThis is a prospective, randomised, non-controlled, multicentre trial. A total of 248 patients will be recruited in this study, and each patient will undergo CT, blood tests, Doppler ultrasound and HVPG measurement. The study consists of two independent and consecutive cohorts: original cohort (124 patients) and validation cohort (124 patients). The researchers will establish and improve the HVPG using biofluid mechanics (HVPGBFM)model in the original cohort and assess the model in the validation cohort.Ethics and disseminationThe study was approved by the Scientific Research Projects Approval Determination of Independent Ethics Committee of Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine (approval number 2017–430 T326). Study findings will be disseminated through peer-reviewed publications and conference presentations.Trial registration numberNCT03470389.

APA, Harvard, Vancouver, ISO, and other styles

27

Siebes, Maria, and Yiannis Ventikos. "The Role of Biofluid Mechanics in the Assessment of Clinical and Pathological Observations." Annals of Biomedical Engineering 38, no. 3 (2010): 1216–24. http://dx.doi.org/10.1007/s10439-010-9903-y.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Erdogan, Abdullah Said. "A Note on the Right-Hand Side Identification Problem Arising in Biofluid Mechanics." Abstract and Applied Analysis 2012 (2012): 1–25. http://dx.doi.org/10.1155/2012/548508.

Full text

Abstract:

The inverse problem of reconstructing the right-hand side (RHS) of a mixed problem for one-dimensional diffusion equation with variable space operator is considered. The well-posedness of this problem in Hölder spaces is established.

APA, Harvard, Vancouver, ISO, and other styles

29

Matsuo, T., R. Okeda, and K. Yamamoto. "Study of biofluid mechanics at arterial bifurcations: Importance of flow division ratio as a parameter." Biorheology 30, no. 3-4 (1993): 267–74. http://dx.doi.org/10.3233/bir-1993-303-411.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Lever, M. J. "Biofluid Mechanics. ByJaganN.Mazumdar. Pp. 191. World Scientific, 1993. £24.00 hardback. ISBN 981 02 0927 4." Experimental Physiology 79, no. 5 (1994): 869–70. http://dx.doi.org/10.1113/expphysiol.1998.sp004277.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Einav, Shmuel, Danny Bluestein, and Morteza Mory Gharib. "Fifth International Biofluid Mechanics Symposium: Position Papers and Key Challenges: Pasadena, March 28–30, 2008." Annals of Biomedical Engineering 38, no. 3 (2010): 1162–63. http://dx.doi.org/10.1007/s10439-010-9906-8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Liu, Yifan, Gang Lu, Junke Chen, and Qigang Zhu. "Exploration of Internal and External Factors of Swimmers’ Performance Based on Biofluid Mechanics and Computer Simulation." International Journal of Environmental Research and Public Health 18, no. 12 (2021): 6471. http://dx.doi.org/10.3390/ijerph18126471.

Full text

Abstract:

The purpose of this study is to explore the influence of different swimming strokes on the performance of swimmers and the resistance of each part from the perspective of hydrodynamics. In this paper, the influence of internal and external factors on the swimming speed is analyzed comprehensively and meticulously from the macro and micro perspectives. In the macroscopic part, the swimming speed representation model is established, and the validity of the model is further verified by the analysis of experimental data and hydrodynamic equations. In the microscopic part, we carefully analyzed details such as the opening angle of the palm, the timing of the arm and leg and the angular velocity of each link of the human body. Combined with computer simulation, stereo modeling and numerical analysis are carried out, and the best scheme FOR how to cooperate with each part of the body in swimming is given.

APA, Harvard, Vancouver, ISO, and other styles

33

Bhargava, R., S. Rawat, H. S. Takhar, and O. Anwar Bég. "Pulsatile magneto-biofluid flow and mass transfer in a non-Darcian porous medium channel." Meccanica 42, no. 3 (2007): 247–62. http://dx.doi.org/10.1007/s11012-007-9052-z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Pan, Caofeng, Ying Fang, Hui Wu, et al. "Generating Electricity from Biofluid with a Nanowire-Based Biofuel Cell for Self-Powered Nanodevices." Advanced Materials 22, no. 47 (2010): 5388–92. http://dx.doi.org/10.1002/adma.201002519.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Foo, Jong Yong Abdiel, and Chu Sing Lim. "Biofluid mechanics of the human reproductive process: modelling of the complex interaction and pathway to the oocytes." Zygote 16, no. 4 (2008): 343–54. http://dx.doi.org/10.1017/s0967199408004899.

Full text

Abstract:

SummaryRecent revelations in the human reproductive process have fuelled much interest in this field of study. In particular, the once prevailing view of large numbers of ejaculated sperms racing towards the egg has been refuted recently. This is opposed to the current views derived from numerous clinical findings that state that only a very small number of sperms will ever enter the oviduct. It is believed that these few sperms must have been guided to make the long, tedious and obstructed journey to the egg. For a mature spermatozoon, its hyperactivated swimming motility upon capacitation plays an important role in the fertilization of a mature egg. Likewise, the female genital tract also provides guiding mechanisms to complement the survival of normal hydrodynamic profile sperms and thus promotes an eventual sperm–egg interaction. Understanding these mechanisms can be essential for the derivation of assisted conception techniques especially those in vitro. With the aid of computational models and simulation, suitability and effectiveness of novel assisted conception methodology can be assessed, particularly for those yet to be ready for clinical trials. This review discusses the possible bioengineering models and the mechanisms by which human spermatozoa are guided to the egg.

APA, Harvard, Vancouver, ISO, and other styles

36

Sanal Kumar, V. R., Bharath Rajaghatta Sundararam, Pradeep Kumar Radhakrishnan, et al. "In vitro prediction of the lower/upper-critical biofluid flow choking index and in vivo demonstration of flow choking in the stenosis artery of the animal with air embolism." Physics of Fluids 34, no. 10 (2022): 101302. http://dx.doi.org/10.1063/5.0105407.

Full text

Abstract:

Diagnostic investigations of aneurysm, hemorrhagic stroke, and other asymptomatic cardiovascular diseases and neurological disorders due to the flow choking (biofluid/boundary layer blockage persuaded flow choking) phenomenon in the circulatory system of humans and animals on the Earth and in the human spaceflight are active research topics of topical interest {Kumar et al., “boundary layer blockage persuaded flow choking leads to hemorrhagic stroke and other neurological disorders in earth and human spaceflight,” Paper presented at the Basic Cardiovascular Sciences Conference, 23–25 August 2021 (American Stroke Association, 2021) [Circ. Res. 129, AP422 (2021)] and “Lopsided blood-thinning drug increases the risk of internal flow choking and shock wave generation causing asymptomatic stroke,” in International Stroke Conference, 19–20 March 2021 (American Stroke Association, 2021) [Stroke 52, AP804 (2021)]}. The theoretical concept of flow choking [Kumar et al., “Lopsided blood-thinning drug increases the risk of internal flow choking leading to shock wave generation causing asymptomatic cardiovascular disease,” Global Challenges 5, 2000076 (2021); “Discovery of nanoscale boundary layer blockage persuaded flow choking in cardiovascular system—Exact prediction of the 3D boundary-layer-blockage factor in nanotubes,” Sci. Rep. 11, 15429 (2021); and “The theoretical prediction of the boundary layer blockage and external flow choking at moving aircraft in ground effects,” Phys. Fluids 33(3), 036108 (2021)] in the cardiovascular system (CVS) due to gas embolism is established herein through analytical, in vitro (Kumar et al., “Nanoscale flow choking and spaceflight effects on cardiovascular risk of astronauts—A new perspective,” AIAA Paper No. 2021-0357, 2021), in silico (Kumar et al., “Boundary layer blockage, Venturi effect and cavitation causing aerodynamic choking and shock waves in human artery leading to hemorrhage and massive heart attack—A new perspective,” AIAA Paper No. 2018-3962, 2018), and in vivo animal methodology [Jayaraman et al., “Animal in vivo: The proof of flow choking and bulging of the downstream region of the stenosis artery due to air embolism,” Paper presented at the Basic Cardiovascular Sciences Conference , 25–28 July 2022 (American Heart Association, 2022)]. The boundary layer blockage persuaded flow choking phenomenon is a compressible viscous flow effect, and it arises at a critical pressure ratio in continuum/non-continuum real-world yocto to yotta scale flow systems and beyond [Kumar et al., “Universal benchmark data of the three-dimensional boundary layer blockage and average friction coefficient for in silico code verification,” Phys. Fluids 34(4), 041301 (2022)]. The closed-form analytical models, capable of predicting the flow choking in CVS, developed from the well-established compressible viscous flow theory are reviewed and presented herein. The lower-critical flow-choking index of the healthy subject (human being/animal) is predicted through the speciation analysis of blood. The upper-critical flow-choking index is predicted from the specific heat of blood at constant pressure (Cp) and constant volume (Cv), estimated using the Differential Scanning Calorimeter. These flow-choking indexes, highlighted in terms of systolic-to-diastolic blood pressure ratio (SBP/DBP), are exclusively controlled by the biofluid/blood heat capacity ratio (BHCR = Cp/Cv). An in vitro study shows that nitrogen (N2), oxygen (O2), and carbon dioxide (CO2) gases are predominant in fresh-blood samples of the healthy humans and Guinea pigs at a temperature range of 37–40 °C (98.6–104 °F) causing gas embolism. In silico results demonstrated the existence of the biofluid/boundary layer blockage persuaded flow choking, stream tube flow choking, shock wave generation, and pressure overshoot in the downstream region of simulated arteries (with and without stenosis), at a critical pressure ratio, due to gas embolism. The flow choking followed by aneurysm (i.e., bulging of the downstream region of the stenosis artery due to shock wave generation) due to air embolism is demonstrated through small animal in vivo studies. We could corroborate herein, with the animal in vivo and three-dimensional in silico studies, that flow-choking followed by shock wave generation and pressure overshoot occurs in arteries with stenosis due to air embolism at a critical pressure ratio. Analytical models reveal that flow-choking occurs at relatively high and low blood viscosities in CVS at a critical blood pressure ratio (BPR), which leads to memory effect (stroke history/arterial stiffness) and asymptomatic cardiovascular diseases [Kumar et al., “Lopsided blood-thinning drug increases the risk of internal flow choking leading to shock wave generation causing asymptomatic cardiovascular disease,” Global Challenges 5, 2000076 (2021)]. We concluded that an overdose of drug for reducing the blood viscosity enhances the risk of flow choking (biofluid/boundary layer blockage persuaded flow choking) due to an enhanced boundary layer blockage (BLB) factor because of the rise in Reynolds number ( Re) and turbulence. An analytical model establishes that an increase in Re due to the individual or the joint effects of fluid density, fluid viscosity, fluid velocity, and the hydraulic diameter of the vessel creates high turbulence level in CVS instigating an escalated BLB factor heading to a rapid adverse flow choking. Therefore, prescribing the exact blood-thinning course of therapy is crucial for achieving the anticipated curative value and further annulling adverse flow choking (biofluid/boundary layer blockage persuaded flow choking) in CVS. We could conclude authoritatively herein, with the animal in vivo studies, that flow choking occurs in the artery with stenosis due to air embolism at a critical BPR (i.e., SBP/DBP = 1.892 9), which is regulated by the heat capacity ratio of air. The cardiovascular risk due to boundary layer blockage persuaded flow choking could be diminished by concurrently reducing the viscosity of biofluid/blood and flow-turbulence. This comprehensive review is a pointer toward achieving relentless unchoked flow conditions (i.e., flow Mach number < 1) in the CVS for prohibiting asymptomatic cardiovascular diseases and neurological disorders associated with flow choking and shock wave generation followed by pressure overshoot causing arterial stiffness. The unchoked flow condition can be achieved in every subject (human/animal) by suitably increasing the thermal-tolerance-level in terms of BHCR and/or by reducing the BPR within the pathophysiological range of individual subjects through the new drug discovery, the new companion drug with the conventional blood thinners and/or proper health care management for increasing the healthy-life span of one and all in the universe.

APA, Harvard, Vancouver, ISO, and other styles

37

Rawat, S., R. Bhargava, Kapoor Saurabh, and S. Sharma. "Sensitivity Analysis of Pulsatile Hydromagnetic Biofluid Flow and Heat Transfer with Non Linear Darcy-Forchheimer Drag." Journal of Applied Fluid Mechanics 9, no. 3 (2016): 1457–65. http://dx.doi.org/10.18869/acadpub.jafm.68.228.24089.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Heakal, Fakiha El-Taib, and Amira M. Bakry. "Electrochemical Characterization of Certain Mg-Based Alloys in Artificial Perspiration Biofluid for Consumer and Industrial Applications." Journal of Materials Engineering and Performance 28, no. 7 (2019): 4379–92. http://dx.doi.org/10.1007/s11665-019-04163-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

FAN, JIZHUANG, WEI ZHANG, YANHE ZHU, and JIE ZHAO. "CFD-BASED SELF-PROPULSION SIMULATION FOR FROG SWIMMING." Journal of Mechanics in Medicine and Biology 14, no. 06 (2014): 1440012. http://dx.doi.org/10.1142/s0219519414400120.

Full text

Abstract:

Mechanism analysis of frog swimming is an interesting subject in the field of biofluid mechanics and bionics. Computing the hydrodynamic forces acting on a frog is difficult due to its characteristics of explosive propulsion and large range of joint motion. To analyze the flow around the body and vortices in the wake, in this paper, the method based on Computational Fluid Dynamics (CFD) was utilized to solve the velocity and pressure distributions in the flow field and on the frog. The hydrodynamic problem during the propulsive phase of a frog, Xenopus laevis, was calculated using the CFD software FLUENT. A self-propulsion simulation was performed which computed the body velocity from the joint trajectory input and CFD solved the hydrodynamic forces, and visual CFD results of the hydrodynamic forces and flow field structures were obtained.

APA, Harvard, Vancouver, ISO, and other styles

40

Einav, S., and M. Sokolov. "An Experimental Study of Pulsatile Pipe Flow in the Transition Range." Journal of Biomechanical Engineering 115, no. 4A (1993): 404–11. http://dx.doi.org/10.1115/1.2895504.

Full text

Abstract:

The study of pulsatile flows is relevant to many areas of applications. Typical applications include aerodynamics, biofluid mechanics, wind flows, and gas transport. Transition to turbulence during pulsatile flow is physiologically and clinically important. It has been suggested as a possible mechanism to enhance the transport of gases during high-frequency ventilation, may be related to valvular regurgitation and heart murmurs and to post stenotic dilatation and aneurysms. Measurements in a pulsatile pipe flow with a superimposed mean flow are reported. Data were taken in a water flow with mean Reynolds numbers in the range of 0 < Rem < 3000, oscillating Reynolds numbers of 0 < Reω < 4000, and Stokes parameter 7 < λ < 15. Velocity profiles of various phases of the flow, condition for flow reversal, and pressure losses were measured. The adequacy of a quasi-steady-state model is discussed. Condition for transition is determined by visually inspecting velocity signals at the centerline.

APA, Harvard, Vancouver, ISO, and other styles

41

SINGH, M., D. LIEPSCH, JOYCE McLEAN, and G. PALLOTTI. "FLOW VISUALIZATION IN RIGHT CORONARY ARTERY BYPASS MODELS." Journal of Mechanics in Medicine and Biology 08, no. 03 (2008): 293–315. http://dx.doi.org/10.1142/s021951940800270x.

Full text

Abstract:

It is well known from fundamental fluid mechanics that separation regions occur at bends and bifurcations of blood vessels. In addition to this, a secondary flow is also created. This means that the flow is moving forward like a vortical plait. Vortices are created that move counterclockwise to each other perpendicular to the mainstream direction. Three-dimensional flow exists, which is totally different to the well-known parabolic flow in straight pipes under laminar flow conditions. Therefore, a short fundamental introduction to biofluid mechanics is presented in this paper. A coronary artery model with different bypasses is shown as an example. The coronary artery is a prominent cardiac vessel often affected by the atherosclerosis process, which can lead to its full blockage. Blood flow is restored by the construction of a bypass performed by implanting part of the saphenous vein. This bypass is subjected to varying flow conditions during the various phases of pulsatile blood flow. For precise location of the regions associated with flow abnormalities, flow visualization through the complete bypass, covering the arterial and bypass sections, is required. This forms the objective of the present work: to visualize flow changes in bypass models of the right coronary artery prior to its bifurcation under pulsatile flow conditions.

APA, Harvard, Vancouver, ISO, and other styles

42

Chandrawat, Rajesh Kumar, and Varun Joshi. "Numerical Solution of the Time-Depending Flow of Immiscible Fluids with Fuzzy Boundary Conditions." International Journal of Mathematical, Engineering and Management Sciences 6, no. 5 (2021): 1315–30. http://dx.doi.org/10.33889/ijmems.2021.6.5.079.

Full text

Abstract:

Fluid flow modeling using fuzzy boundary conditions is one of the viable areas in biofluid mechanics, drug suspension in pharmacology, as well as in the cytology and electrohydrodynamic analysis of cerebrospinal fluid data. In this article, a fuzzy solution for the two immiscible fluid flow problems is developed, which is motivated by biomechanical flow engineering. Two immiscible fluids, namely micropolar and Newtonian fluid, are considered with fuzzy boundary conditions in the horizontal channel. The flow is considered unsteady and carried out by applying a constant pressure gradient in the X-direction of the channel. The coupled partial differential equations are modeled for fuzzy profiles of velocity and micro-rotation vectors then the numerical results are obtained by the modified cubic B - spline differential quadrature method. The evolution of membership grades for velocity and microrotation profiles has been depicted with the fuzzy boundaries at the channel wall. It is observed that Micropolar fluid has a higher velocity change than Newtonian fluid, and both profiles indicate a declining nature toward the interface.

APA, Harvard, Vancouver, ISO, and other styles

43

Carvalho, Denise, Ana Rodrigues, Vera Faustino, Diana Pinho, Elisabete Castanheira, and Rui Lima. "Microfluidic Deformability Study of an Innovative Blood Analogue Fluid Based on Giant Unilamellar Vesicles." Journal of Functional Biomaterials 9, no. 4 (2018): 70. http://dx.doi.org/10.3390/jfb9040070.

Full text

Abstract:

Blood analogues have long been a topic of interest in biofluid mechanics due to the safety and ethical issues involved in the collection and handling of blood samples. Although the current blood analogue fluids can adequately mimic the rheological properties of blood from a macroscopic point of view, at the microscopic level blood analogues need further development and improvement. In this work, an innovative blood analogue containing giant unilamellar vesicles (GUVs) was developed to mimic the flow behavior of red blood cells (RBCs). A natural lipid mixture, soybean lecithin, was used for the GUVs preparation, and three different lipid concentrations were tested (1 × 10−3 M, 2 × 10−3 M and 4 × 10−3 M). GUV solutions were prepared by thin film hydration with a buffer, followed by extrusion. It was found that GUVs present diameters between 5 and 7 µm which are close to the size of human RBCs. Experimental flow studies of three different GUV solutions were performed in a hyperbolic-shaped microchannel in order to measure the GUVs deformability when subjected to a homogeneous extensional flow. The result of the deformation index (DI) of the GUVs was about 0.5, which is in good agreement with the human RBC’s DI. Hence, the GUVs developed in this study are a promising way to mimic the mechanical properties of the RBCs and to further develop particulate blood analogues with flow properties closer to those of real blood.

APA, Harvard, Vancouver, ISO, and other styles

44

Jing, Peng, Satoshi Ii, Xiaolong Wang, Kazuyasu Sugiyama, Shigeho Noda, and Xiaobo Gong. "Effects of fluid–cell–vessel interactions on the membrane tensions of circulating tumor cells in capillary blood flows." Physics of Fluids 34, no. 3 (2022): 031904. http://dx.doi.org/10.1063/5.0080488.

Full text

Abstract:

The membrane tensions of suspended nucleated cells moving in blood flows in capillary networks are quite different from those of spreading cells, a fact that is crucial to many pathological processes, such as the metastasis of cancers via circulating tumor cells (CTCs). However, a few studies have examined membrane tensions in suspended cells, especially when interacting with other cells of different stiffnesses in low-Reynolds number flows at the cellular level. Taking CTCs as an example, we use the immersed boundary method to analyze the relationship between membrane tensions and their motional behaviors under the influence of fluid–cell–vessel interactions. The effects of vessel diameter and hematocrit on the shear tension and average isotropic tension are also analyzed. The results suggest that the confinement of the vessel wall determines membrane tensions on CTCs until the ratio of the vessel diameter to cell size becomes slightly larger than unity, at which point cell–cell interactions become the crucial factor. The increase in interactions between red blood cells and CTCs with the increase in the hematocrit in larger vessels promotes membrane tensions not only through the migration of CTCs to the vessel wall but also through a reduction in the translational motion and rotation of CTCs. The present study provides support rooted in biofluid mechanics for mechanobiological research on the metastasis and apoptosis of CTCs in microvessels.

APA, Harvard, Vancouver, ISO, and other styles

45

Lee, Ki Bang. "Two-step activation of paper batteries for high power generation: design and fabrication of biofluid- and water-activated paper batteries." Journal of Micromechanics and Microengineering 16, no. 11 (2006): 2312–17. http://dx.doi.org/10.1088/0960-1317/16/11/009.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Kiris, C., D. Kwak, S. Rogers, and I.-D. Chang. "Computational Approach for Probing the Flow Through Artificial Heart Devices." Journal of Biomechanical Engineering 119, no. 4 (1997): 452–60. http://dx.doi.org/10.1115/1.2798293.

Full text

Abstract:

Computational fluid dynamics (CFD) has become an indispensable part of aerospace research and design. The solution procedure for incompressible Navier–Stokes equations can be used for biofluid mechanics research. The computational approach provides detailed knowledge of the flowfield complementary to that obtained by experimental measurements. This paper illustrates the extension of CFD techniques to artificial heart flow simulation. Unsteady incompressible Navier–Stokes equations written in three-dimensional generalized curvilinear coordinates are solved iteratively at each physical time step until the incompressibility condition is satisfied. The solution method is based on the pseudocompressibility approach. It uses an implicit upwind-differencing scheme together with the Gauss–Seidel line-relaxation method. The efficiency and robustness of the time-accurate formulation of the numerical algorithm are tested by computing the flow through model geometries. A channel flow with a moving indentation is computed and validated by experimental measurements and other numerical solutions. In order to handle the geometric complexity and the moving boundary problems, a zonal method and an overlapped grid embedding scheme are employed, respectively. Steady-state solutions for the flow through a tilting-disk heart valve are compared with experimental measurements. Good agreement is obtained. Aided by experimental data, the flow through an entire Penn State artificial heart model is computed.

APA, Harvard, Vancouver, ISO, and other styles

47

Oldenburg, Jan, Wiebke Wollenberg, Finja Borowski, Klaus-Peter Schmitz, Michael Stiehm, and Alper Öner. "Augmentation of experimentally obtained flow fields by means of Physics Informed Neural Networks (PINN) demonstrated on aneurysm flow." Current Directions in Biomedical Engineering 9, no. 1 (2023): 519–23. http://dx.doi.org/10.1515/cdbme-2023-1130.

Full text

Abstract:

Abstract Biofluid mechanics play an important role in the study of the mechanism of cardiovascular diseases and in the development of new implants. For the assessment of hydrodynamic parameters, experimental methods as well as in-silico approaches can be used, such as particle image velocimetry (PIV) and Deep Learning, respectively. Challenges for PIV are the optical access to the region of interest, and time consumption for measuring and post-processing analysis in particular for three dimensional flow. To overcome these limitations state-of-the-art deep learning algorithms could be utilized to augment spatially coarse resolved flow fields. In this study, we demonstrate the use of Physics Informed Neural Networks (PINN) to augment PIV measurement data. To demonstrate a combined workflow, we investigate the flow of a Newtonian fluid through a simplified aneurysm under laminar conditions. Generation of synthetic PIV particle images of a single measurement plane and the corresponding PIV vector calculations were performed as the basis for the PINN algorithm. Based on the Navier-Stokes equations the PINN reconstructs the entire 3D flow field and pressure distribution inside the aneurysm. We observed qualitative agreements between ground through data and PINN predictions. Nevertheless, there are substantial differences in the quantitative, locally resolved comparison of the flow metrics, despite the generally tendency for the PINN algorithm to correctly augment the flow field.

APA, Harvard, Vancouver, ISO, and other styles

48

Wang, Ziran, Zhuang Hao, Shifeng Yu, Cong Huang, Yunlu Pan, and Xuezeng Zhao. "A Wearable and Deformable Graphene-Based Affinity Nanosensor for Monitoring of Cytokines in Biofluids." Nanomaterials 10, no. 8 (2020): 1503. http://dx.doi.org/10.3390/nano10081503.

Full text

Abstract:

A wearable and deformable graphene-based field-effect transistor biosensor is presented that uses aptamer-modified graphene as the conducting channel, which is capable of the sensitive, consistent and time-resolved detection of cytokines in human biofluids. Based on an ultrathin substrate, the biosensor offers a high level of mechanical durability and consistent sensing responses, while conforming to non-planar surfaces such as the human body and withstanding large deformations (e.g., bending and stretching). Moreover, a nonionic surfactant is employed to minimize the nonspecific adsorption of the biosensor, hence enabling cytokine detection (TNF-α and IFN-γ, significant inflammatory cytokines, are used as representatives) in artificial tears (used as a biofluid representative). The experimental results demonstrate that the biosensor very consistently and sensitively detects TNF-α and IFN-γ, with limits of detection down to 2.75 and 2.89 pM, respectively. The biosensor, which undergoes large deformations, can thus potentially provide a consistent and sensitive detection of cytokines in the human body.

APA, Harvard, Vancouver, ISO, and other styles

49

Singh, Akhileshwar, Krishna Murari Pandey, and Yogesh Singh. "Triggering the Splitting Dynamics of Low-Viscous Fingers through Surface Wettability Inside Bifurcating Channel." Mathematical Problems in Engineering 2022 (February 10, 2022): 1–14. http://dx.doi.org/10.1155/2022/3462844.

Full text

Abstract:

This work presents the splitting dynamics of low-viscous fingers inside the single bifurcating channel through the surface wettability of daughter branches. The propagation of low-viscous fingers inside branching microchannels have importance in many applications, such as microfluidics, biofluid mechanics (pulmonary airway reopening), and biochemical testing. Several numerical simulations are performed where a water finger propagates inside the silicon oil-filled bifurcating channel, and at the bifurcating tip, it splits into two fingers and these fingers propagate into the separate daughter branches. It is noticed that the behaviour of finger splitting at the bifurcating tip depends upon numerous parameters such as surface wettability, capillary number, viscosity ratio, and surface tension. This study aims to trigger the behaviour of finger splitting through the surface wettability of daughter branches θ 1 , θ 2 . Therefore, a series of numerical simulations are performed by considering four different surface wettability configurations of daughter branches, i.e., θ 1 , θ 2 ∈ 78 ° , 78 ° ; 78 ° , 118 ° ; 78 ° , 150 ° ; 150 ° , 150 ° . According to the results obtained from numerical simulations, finger splitting may be categorized into three types based on splitting ratio λ , i.e., symmetrical splitting, nonsymmetrical splitting, and reversal (no) splitting. It is noticed that the surface wettability of both daughter branches is either hydrophilic 78 ° , 78 ° or superhydrophobic 150 ° , 150 ° , providing symmetrical splitting. The surface wettability of one of the daughter branches is hydrophilic and another is hydrophobic 78 ° , 118 ° , providing nonsymmetrical splitting. The surface wettability of one of the daughter branches is hydrophilic and another is superhydrophobic 78 ° , 150 ° , providing reversal splitting. The findings of this investigation may be incorporated in the fields of biochemical testing and occulted pulmonary airways reopening as well as respiratory diseases such as COVID-19.

APA, Harvard, Vancouver, ISO, and other styles

50

Timsina, Ramesh Chandra. "Mathematical Models on Mechanics of Biofluids." Patan Pragya 13, no. 1 (2024): 64–76. http://dx.doi.org/10.3126/pragya.v13i1.71183.

Full text

Abstract:

In this work, we study the mathematical models of flows for some biofluids. In biomechanics, peristaltic flow plays an important role in which the motion generated in the fluid contained in a distensible tube when a progressive wave of area contraction and expansion travels along the wall of the tube. We consider the effect of elasticity of the tube wall in the flow through the progressive wave travelling along its length without its direct calculation. Since the no – slip condition has used on a moving undulating wall surface, it determines the sinusoidal boundary conditions on the upper and lower wall of the tube. The wide occurrence of peristaltic motion gives its result physiologically from neuro-muscular properties of any tubular smooth muscle.

APA, Harvard, Vancouver, ISO, and other styles

Journal articles on the topic 'Biofluid mechanics'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles