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Dissertations / Theses on the topic 'Bioimaging applications'

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1

Daniels, Ruth. "Multimetallic emitters for bioimaging and display applications." Thesis, Northumbria University, 2017. http://nrl.northumbria.ac.uk/36272/.

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The luminescent properties of transition metal complexes of heavy metals such as platinum(II) and irdium(III) are often highly luminescent and therefore are interesting for use as phosphorescent dopants in organic light-emitting diodes (OLEDs) and as luminescent probes in bioimaging. The majority of complexes investigated to date contain only one metal centre with multimetallic complexes becoming more widely studied in recent decades. This work explores the synthesis of novel dinuclear emitters based on cyclometallated Pt(II) and Ir(III) centres. In particular, complexes in which the metal cen
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2

Colon, Gomez Maria. "Squaraine dyes for two-photon fluorescence bioimaging applications." Honors in the Major Thesis, University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/834.

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3

Pramanik, Goutam [Verfasser]. "Near InfraRed (NIR) nanoemitters for bioimaging applications / Goutam Pramanik." Ulm : Universität Ulm. Fakultät für Naturwissenschaften, 2014. http://d-nb.info/1049238583/34.

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4

Bibikova, O. (Olga). "Plasmon-resonant gold nanoparticles for bioimaging and sensing applications." Doctoral thesis, Oulun yliopisto, 2018. http://urn.fi/urn:isbn:9789526219974.

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Abstract This thesis reports on studies of plasmonic nanoparticles and particularly gold nanostars as signal enhancers and contrast agents for biophotonic applications including visualisation, treatment of living cells and chemical sensing. In this thesis, the optical properties of nanoparticles of different size and morphology and their silica composites were compared. Because they are the most suitable plasmonic nanostructures, gold nanostars were utilised for optical imaging modalities such as confocal microscopy and Doppler optical coherence tomography. The ability of gold nanoparticles to
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5

Kong, Yifei. "Multifunctional fluorescent nanoparticle-bioconjugates : preparation, characterisation and bioimaging applications." Thesis, University of Leeds, 2015. http://etheses.whiterose.ac.uk/12252/.

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6

Ma, Yun. "Photofunctional molecular materials for chemical sensing, bioimaging and electrochromic applications." HKBU Institutional Repository, 2015. https://repository.hkbu.edu.hk/etd_oa/206.

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This thesis is dedicated to developing novel photofunctional molecular materials for the applications in chemical sensing, bioimaging and electrochromic. To begin with, a brief introduction of photofunctional molecular materials and an overview of their applications in chemical sensing, bioimaging and electrochromic were presented in Chapter 1. In chapter 2, we have synthesized a series of water-soluble phosphorescent cationic iridium(III) solvato complexes (1-7) as multicolor cellular probes for imaging in living cells. All of these complexes can be dissolved in PBS. The emission of compl
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7

Yan, Huan. "MICRO- AND NANO-MATERIALS FOR DRUG DELIVERY AND BIOIMAGING APPLICATIONS." Kent State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1428155172.

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8

Glowacka, Paulina. "Synthesis of diene ligands with H-bonding capabilities for bioimaging applications." Thesis, University of East Anglia, 2015. https://ueaeprints.uea.ac.uk/53391/.

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Investigations of the synthesis of novel bioprobes (Scheme A), potentially useful in bioreactions and sugar sensing, are described. A preliminary study is reported that aims to validate the feasibility of tricarbonyl iron complexes and their derivatives in applications as a constituent part of IR/fluorescent bioprobes. Infrared spectroscopy has significant potential in studying these carbonylmetal-based bioprobes, as the MCO signals fall in a window in the water background spectrum at about 2000 cm–1 where absorptions of most of organic functional groups are absent. Their narrow vibrational st
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9

Trofymchuk, Kateryna. "Controlled switching of fluorescent organic nanoparticles through energy transfer for bioimaging applications." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAJ121/document.

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Les performances des techniques de bioimagerie et de biodétection peuvent être améliorées grâce aux nanoparticules fluorescentes (NPs) permettant un transfert d’énergie résonante de type Förster (FRET) efficace. Le but de mon projet de thèse est le développement de NPs polymériques brillantes et ultrastables encapsulant des fluorophores, capables de produire un FRET au-delà du rayon de Förster. Il a été montré que les groupements encombrés sont essentiels pour minimiser l’auto-extinction et le blanchiment des fluorophores encapsulés. Par ailleurs, la matrice polymérique joue un rôle crucial da
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10

Nguyen, Dao. "Design, Synthesis, and Characterization of Novel Hydrophilic Fluorene-Based Derivatives for Bioimaging Applications." Doctoral diss., University of Central Florida, 2009. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2842.

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In this work, hydrophilic fluorene-based derivatives that contain ethylene oxide substituents, have been synthesized and characterized for potential use as new fluorophores for bioimaging applications and for fluorescence sensing of heavy metals. Symmetrical and unsymmetrical fluorene derivatives based on structural types of acceptor-pi-acceptor, acceptor-pi-donor, and donor-pi-donor were characterized by TGA, UV-vis absorption, fluorescence emission, lifetime, anisotropy, and two-photon absorption (2PA) cross section. They were found to possess high thermal stability, high photostability, hig
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11

Beasley, Jeremy. "Synthesis, characterization, and luminescent properties of Eu3+ dipyridophenazine functionalized complexes for potential bioimaging applications." Thesis, Western Carolina University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1570323.

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<p> Luminescent properties of lanthanide complexes possess unique characteristics that make them good candidates for possible bioimaging agents and have inspired research initiatives to further explore these materials. However, the toxicity of these metals limits their applications as in-vivo bioimaging agents. One solution that eliminates the toxic effects is to encase these lanthanide complexes in silica. This project was designed to probe the variation in the fluorescence properties of a highly luminescent europium (III) complex, utilizing a fluorinated &acirc;-diketonate ligand (theno
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12

Nsubuga, Anne [Verfasser], Jörg [Gutachter] Steinbach, and Michael U. [Gutachter] Kumke. "Upconverting luminescent nanoparticles for bioimaging applications / Anne Nsubuga ; Gutachter: Jörg Steinbach, Michael U. Kumke." Dresden : Technische Universität Dresden, 2019. http://d-nb.info/1226901344/34.

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13

Ishaq, Omer. "Image Analysis and Deep Learning for Applications in Microscopy." Doctoral thesis, Uppsala universitet, Avdelningen för visuell information och interaktion, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-283846.

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Quantitative microscopy deals with the extraction of quantitative measurements from samples observed under a microscope. Recent developments in microscopy systems, sample preparation and handling techniques have enabled high throughput biological experiments resulting in large amounts of image data, at biological scales ranging from subcellular structures such as fluorescently tagged nucleic acid sequences to whole organisms such as zebrafish embryos. Consequently, methods and algorithms for automated quantitative analysis of these images have become increasingly important. These methods range
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14

Siegl, Sebastian [Verfasser], and Thomas [Akademischer Betreuer] Carell. "Bioorthogonal reactions of heterodienes: synthesis, reactivity and fluorogenic bioimaging applications / Sebastian Siegl ; Betreuer: Thomas Carell." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2020. http://d-nb.info/1232645443/34.

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15

Ddungu, John. "Synthesis and characterisation of silicon-based nanoparticles for diagnostic applications." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAF063.

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Dans le cadre de cette thèse intitulée “Synthèse et caractérisation de nanoparticules à base de silicium pour des applications de diagnostique”, nous avons conçu des nanosondes basées sur des systèmes de petites nanoparticules à base de silicium (&lt;5 nm) (NPs) portant différentes molécules fonctionnelles sur leur surface. Les NPs de Si ont été synthétisées, caractérisées et fonctionnalisées pour une utilisation dans les applications d'imagerie in vivo et d'électrochimiluminescence (ECL). Pour l’imagerie, une sonde active de tomographie par émission de positrons (TEP) et un colorant émissif o
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Huth, Katharina [Verfasser]. "Synthesis and characterization of water-soluble dendronized dye systems as fluorescent labels for bioimaging applications / Katharina Huth." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1171431244/34.

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17

Cepraga, Cristina. "Two-photon chromophore-polymer conjugates grafted onto gold nanoparticles as fluorescent probes for bioimaging and photodynamic therapy applications." Phd thesis, INSA de Lyon, 2012. http://tel.archives-ouvertes.fr/tel-00863765.

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Photodynamic therapy (PDT) is an alternative treatment of cancer requiring the use of chromophore molecules (photosensitizers), which can induce cell death after light excitation. Gold nanoparticles (AuNP), exhibiting localized Surface Plasmon Resonance, can enhance the photophysical response of chromophores located in their vicinity, and thus improve their therapeutic action. Moreover, the use of highly localized two-photon chromophores (photosensitizers and fluorophores), capable to undergo a localized excitation by light in the Near InfraRed region, should increase the penetration depth int
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Hopper, Andrew. "Development of functionalised carbon based substrates for neuronal cell culture and production of carbon nanoparticles for bioimaging applications." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/8473/.

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The desire to create an idealised substrate for the growth of neural based cells has been a research ambition for many years. Neural based cells are notoriously difficult to culture, normally requiring the creation of a specially prepared substrate to allow for their attachment, growth and differentiation. Although polylysine serves as an adequate functional treatment for this purpose in vitro its associated cytotoxicity present difficulties for in vivo applications. Although progress has been made in recent years with regards to the initial development of brain computer interfaces (BCIs) and
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19

Hales, Katherine J. "Synthesis, Characterizations, and Evaluation of New Reactive Two-Photon Absorbing Dyes for Two-Photon Excited Fluorescence Imaging Applications." Doctoral diss., University of Central Florida, 2005. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3575.

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Recent, cooperative advances in chemistry, biology, computing, photophysics, optics, and microelectronics have resulted in extraordinary developments in the biological sciences, resulting in the emergence of a novel area termed 'biophotonics'. The integrative and interdisciplinary nature of biophotonics cuts across virtually all disciplines, extending the frontiers of basic cellular, molecular, and biology research through the clinical and pharmaceutical industries. This holds true for the development and application of the novel imaging modality utilizing multiphoton absorption and its extrao
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20

Andrade, Carolina D. "Design, synthesis and characterization of new two-photon absorbing (2PA) fluorescent dyes and bioconjugates, and their applications in bioimaging." Doctoral diss., University of Central Florida, 2010. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4553.

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The development of new multiphoton absorbing materials has attracted the attention of researchers for the last two decades. The advantages that multiphoton absorbing materials offer, versus their one-photon absorbing counterparts, rely on the nature of the nonlinearity of the absorption process, where two photons are absorbed simultaneously offering increased 3D resolution, deeper penetration, and less photobleaching and photodamage as a result of a more confined excitation. The applications of efficient two-photon absorbing materials have been extensively expanding into the fields of photodyn
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21

Berbel, Manaia Eloísa. "Conception de Quantum dots à base d’oxyde de zinc (ZnO) pour des applications en bio-imagerie de nanosystèmes lipidiques." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS127/document.

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Les systèmes théranostiques, consistant en un dispositif unique contenant des agents de diagnostic et des principes actifs, suscitent un interêt accru car ils peuvent améliorer le traitement de maladies telles que le cancer en réduisant les effets secondaires des médicaments et en permettant un suivi du traitement. L’objectif de ce travail était d’insérer des Quantum Dots (QDs) à base de ZnO dans des nanoparticules lipidiques pouvant délivrer un principe actif anti-cancéreux. Nous avons d’abord cherché à synthétiser des QDs présentant une structure coeur-coquille ZnO/ZnS pour améliorer leurs p
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22

Zhang, Yuanwei. "Squaraine dyes, design and synthesis for various functional materials applications." Doctoral diss., University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/6392.

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This dissertation contains the synthesis and characterization of squaraine based new functional materials. In the first part of this thesis work, a water soluble benzothiazolium squaraine dye was synthesized with pyridium pendents, and controlled aggregation properties were achieved. After formation of partially reversible J-aggregation on a polyelectrolyte (poly(acryl acid) sodium salt) template, the nonlinear, two-photon absorption cross section per repeat unit was found to be above 30-fold enhanced compared with nonaggregate and/or low aggregates. Using a similar strategy, sulfonate anions
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23

Fiorini, Federica. "Soft hybrid materials for cell growth and proliferation." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAF027/document.

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Le travail de recherche consiste à développer des hydrogels pour la prolifération et la migration cellulaires in vitro et in vivo en trois dimensions (3D). Des hydrogels à base de polyamidoamines avec d'intéressantes propriétés physicochimiques et une remarquable biocompatibilité ont été développés pour différentes applications biomédicales. Un hydrogel avec des sondes luminescentes d’iridium(III) incorporés de manière covalente, a été conçue comme plate-forme 3D de culture cellulaire, pour la visualisation directe des cellules vivantes en temps réel, et a démontré être un puissant outil de bi
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24

Osipovich, Nikolai P., Sergei K. Poznyak, Vladimir Lesnyak, and Nikolai Gaponik. "Cyclic voltammetry as a sensitive method for in situ probing of chemical transformations in quantum dots." Royal Society of Chemistry, 2016. https://tud.qucosa.de/id/qucosa%3A36419.

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The application of electrochemical methods for the characterization of colloidal quantum dots (QDs) attracts considerable attention as these methods may allow for monitoring of some crucial parameters, such as energetic levels of conduction and valence bands as well as surface traps and ligands under real conditions of colloidal solution. In the present work we extend the applications of cyclic voltammetry (CV) to in situ monitoring of degradation processes of water-soluble CdTe QDs. This degradation occurs under lowering of pH to the values around 5, i.e. under conditions relevant to bioimagi
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John, Sween. "A Study of the Synthesis and Surface Modification of UV Emitting Zinc Oxide for Bio-Medical Applications." Thesis, University of North Texas, 2009. https://digital.library.unt.edu/ark:/67531/metadc10990/.

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This thesis presents a novel ZnO-hydrogel based fluorescent colloidal semiconductor nanomaterial system for potential bio-medical applications such as bio-imaging, cancer detection and therapy. The preparation of ZnO nanoparticles and their surface modification to make a biocompatible material with enhanced optical properties is discussed. High quality ZnO nanoparticles with UV band edge emission are prepared using gas evaporation method. Semiconductor materials including ZnO are insoluble in water. Since biological applications require water soluble nanomaterials, ZnO nanoparticles are first
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26

Shulov, Ievgen. "Synthesis of fluorescent organic nanoparticles for biological applications." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAJ001/document.

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Boîtes quantiques (QDs) et nanoparticules fluorescentes de silice (NPs) ont influencé le domaine de la bioimagerie de par leur forte luminosité et photostabilité. Par rapport aux QDs, les NPs organiques peuvent s’avérer être encore plus brillantes et entièrement biodégradables, avec une bonne biocompatibilité et sans contenir aucun élément toxique. Nous avons développé quatre types de ces NPs : en premier, des nano-gouttelettes lipidiques chargées de colorants lipophiles (flavone et Nil Rouge) pour l'imagerie in vivo chez le poisson zèbre ; en second, l’association ionique entre rhodamine B al
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Le, Montagner Yoann. "Solutions algorithmiques pour des applications d'acquisition parcimonieuse en bio-imagerie optique." Phd thesis, Telecom ParisTech, 2013. http://tel.archives-ouvertes.fr/tel-00950365.

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Ces dernières années, la théorie mathématique de l'échantillonnage compressé (compressed sensing, CS) a émergé en tant que nouvel outil en traitement d'images, permettant notamment de dépasser certaines limites établies par la théorie de l'échantillonnage de Nyquist. En particulier, la théorie du CS établit qu'un signal (une image, une séquence vidéo, etc.) peut être reconstruit à partir d'un faible nombre de mesures linéaires non-adaptatives et aléatoires, pourvu qu'il présente une structure parcimonieuse. Dans la mesure où cette hypothèse se vérifie pour une large cla
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Epelde, Elezcano Nerea. "Matériaux Hybrides nanostructures photoactifs pour des applications optiques et biomédicales." Thesis, Pau, 2016. http://www.theses.fr/2016PAUU3007/document.

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Dans ce manuscrit, la synthèse et la caractérisation complète de différents matériaux hybrides dédiés à des applications dans le domaine optique ou thérapeutique sont décrites. Dans un premier temps, des systèmes macroscopiquement ordonnés sont obtenus par intercalation de colorants tels que le Styryl 722 ou la pyronine-Y dans plusieurs films à base d’argile de type smectite. Les films d’argile sont élaborés par spin-coating et les colorants intercalés par immersion des films dans les solutions de ces colorants. Les effets de l’argile sur les propriétés des colorants sont analysés en détail et
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Ho, Ka-kin, and 何家健. "Diethylenetriaminepentaacetic acid (DTPA) based lanthanide (III) complexes for bioimaging application." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B49799344.

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In this work, a series of DTPA based Ln complexes containing one or two chromophores with different degrees of conjugation were synthesized. The proton relaxivities of Gd(III) analogues were investigated as potential MRI contrast agents while the photoluminescence of Eu(III) and Tb(III) analogues were studied for their applications in optical probes for cellular imaging. Later investigation indicates that only emissions from the chromophores could be measured upon long wavelength photon excitations in the microscope. With suitable ligand design, novel dual functional imaging probes were final
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Si, Yang. "Fluorescent Nanomaterials for Bioimaging and Biosensing : Application on E.coli Bacteria." Thesis, Cachan, Ecole normale supérieure, 2015. http://www.theses.fr/2015DENS0038/document.

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Les bactéries sont les organismes les plus abondants dans le monde. Des études sur les bactéries peuvent être bénéfiques pour la recherche médicale, la qualité des ressources en eau et l'industrie alimentaire. La détection et le marquage fluorescent est une des méthodes les plus utilisées pour des objectifs bioanalytiques. Dans la recherche de marqueurs luminescents et stables, des nouvelles nanoparticules fluorescentes et auto-stabilisées à base de polymères (FNPs, 60 nm) et des chaînes de polymères fluorescents (FPCs, 5nm) ont été développées. Dans un premier chapitre, une méthodologie pour
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Grimes, Logan. "DEVELOPENT OF A PHOSPHOLIPID ENCAPSULATION PROCESS FOR QUANTUM DOTS TO BE USED IN BIOLOGIC APPLICATIONS." DigitalCommons@CalPoly, 2014. https://digitalcommons.calpoly.edu/theses/1237.

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The American Cancer Society predicts that 1,665,540 people will be diagnosed with cancer, and 585,720 people will die from cancer in 2014. One of the most common types of cancer in the United States is skin cancer. Melanoma alone is predicted to account for 10,000 of the cancer related deaths in 2014. As a highly mobile and aggressive form of cancer, melanoma is difficult to fight once it has metastasized through the body. Early detection in such varieties of cancer is critical in improving survival rates in afflicted patients. Present methods of detection rely on visual examination of suspici
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Smith, Shea C. "LASER SCANNING CONFOCAL MICROSCOPY (LSCM): AN APPLICATION FOR THE DETECTION OF MORPHOLOGICAL ALTERATIONS IN SKIN STRUCTURE." DigitalCommons@CalPoly, 2009. https://digitalcommons.calpoly.edu/theses/198.

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Laser scanning confocal microscopy (LSCM) is an optical imaging technique that provides improved resolution and sensitivity over conventional methods of optical microscopy. However, the cost of most commercial LSCM systems exceeds the financial limitations of many smaller laboratories. The design of a custom LSCM created at a fraction of the cost of a commercial model is discussed in this paper. The increase in the incidence rate of skin cancer in the world today is alarming, as such, it is essential to provide an early, rapid and effective method for in vivo diagnostics of human skin tissue.
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Di, Maria Francesca Giulia <1978&gt. "Molecular and Supramolecular Engineering of Thiophene Based Materials for Application in Organic Electronics and Bioimaging." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amsdottorato.unibo.it/7620/.

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Thiophene based oligomers and polymers are of great current interest from a scientific and technological point of view for their numerous properties: they are electroactive, fluorescent, chemically stable and allow a great diversity in molecular structures and a fine tuning of functional characteristics. They display ‘plasticity’ in adapting their geometry to the environment in the solid state and in creating supramolecular architectures by self-organization. Moreover, they have the capability to finely interact with biologically relevant molecules such as intracellular proteins. All these pro
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Moore, Christopher S. "Study of Immobilizing Cadmium Selenide Quantum Dots in Selected Polymers for Application in Peroxyoxalate Chemiluminescence Flow Injection Analysis." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etd/1151.

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Two batches of CdSe QDs with different sizes were synthesized for immobilizing in polyisoprene (PI), polymethylmethacrylate (PMMA), and low-density polyethylene (LDPE). The combinations of QDs and polymer substrates were evaluated for their analytical fit-for-use in applicable immunoassays. Hydrogen peroxide standards were injected into the flow injection analyzer (FIA) constructed to simulate enzyme-generated hydrogen peroxide reacting with bis-(2,4,6-trichlorophenyl) oxalate. Linear correlations between hydrogen peroxide and chemilumenscent intensities yielded regression values greater than
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Urnauer, Sarah [Verfasser], and Ernst [Akademischer Betreuer] Wagner. "Improved synthetic gene delivery vehicles for advanced bioimaging-guided tumor-targeted application of the sodium iodide symporter (NIS) as theranostic gene / Sarah Urnauer ; Betreuer: Ernst Wagner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/1148941177/34.

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Nsubuga, Anne. "Upconverting luminescent nanoparticles for bioimaging applications." 2019. https://tud.qucosa.de/id/qucosa%3A34248.

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The synthesis and surface modification of upconverting nanoparticles (UCNPs) composed of a host lattice NaYF4 doped with sensitizers (Yb3+, Nd3+) and luminescent emitters (Er3+) were investigated for potential integration in biological applications.The fascination of NaYF4: Nd3+, Yb3+, Er3+ upconverting nanoparticles derives from their capacity to be excited in the biologically transparent window (650-950 nm) enabling deep tissue penetration. In particular, the ability to convert near infrared radiation into visible light (upconversion), which prevents autofluorescence and over-heating effect
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"Transfer Learning for BioImaging and Bilingual Applications." Doctoral diss., 2015. http://hdl.handle.net/2286/R.I.36027.

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abstract: Discriminative learning when training and test data belong to different distributions is a challenging and complex task. Often times we have very few or no labeled data from the test or target distribution, but we may have plenty of labeled data from one or multiple related sources with different distributions. Due to its capability of migrating knowledge from related domains, transfer learning has shown to be effective for cross-domain learning problems. In this dissertation, I carry out research along this direction with a particular focus on designing efficient and effective algor
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Ma, Nan. "Nucleic acids-templated semiconductor nanocrystals: Synthesis and bioimaging applications." 2009. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=968409&T=F.

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Quek, Chai Hoon. "Near-Infrared Quantum Dots For Bioimaging And Targeting Applications." Diss., 2014. http://hdl.handle.net/10161/9389.

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<p>Luminescent semiconductor nanocrystals or quantum dots (QDs) offer attractive characteristics as a new class of fluorescent probes for molecular, cellular and in vivo imaging. While traditional cadmium-containing QDs have been widely used in biomedical research, diagnostics, and drug delivery, the cytotoxicity arising from the release of Cd2+ ions caused by the degradation of the surface coating is deemed to be a shortfall of cadmium-based QDs for long-term cellular and in vivo imaging. Here we report a direct synthesis of silver-doped zinc selenide QDs in water with near-infrared tunable f
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Kao, Chia-Yun, and 高嘉鄖. "Optical Properties of Fluorescent Proteins and Their Applications in Bioimaging." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/16348386449264065643.

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碩士<br>中原大學<br>應用物理研究所<br>95<br>Recently, the exogenous fluorescent agent has been applied to bio-imaging techniques widely. In different fluorescent agents, the green fluorescent agent has high-stability and high-luminescence efficiency superior in itself, thus, it usually used to the lable of noninvasive molecular and cell biology. It also use to monitor the gene phenomenon, rotein distribution, and protein interaction at the same time. In the thesis, we offer a spectrum analyzing system to use to analysis the fluorescent property changing of the sample in different temperature, and then, we
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Mei-YiLiao and 廖美儀. "Manganese iron oxide nanostructures for catalysis, photothermal therapy and bioimaging applications." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/39169407281229631510.

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博士<br>國立成功大學<br>化學系碩博士班<br>100<br>Part I: Innovative ligand-assisted synthesis of NIR-activated iron oxide as a promising theranostic agent for MRI-guided photothermal therapy A new near-infrared (NIR)-activated Fe3O4 nanostructure was synthesized using a ligand-assisted hydrothermal process with carboxylate ligand and MOF-related ligand. No additional photoabsorbers (i.e., Au nanoshells, Au nanorods, or organic dyes) were necessary in this one-pot reaction. Fourier-transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS) analyses indicated that the carboxylate molecu
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Liu, Yu-Hao, and 劉育豪. "Organic pi-Conjugated Self-assembled Nanomaterials in the Applications of Bioimaging." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/7edrrg.

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碩士<br>國立交通大學<br>材料科學與工程學系奈米科技碩博士班<br>103<br>In this study, the pi conjugated systems are modified by attaching to peptide sequence to gain some functionality or improvement. This thesis has two different parts. In the first part, we study the rheological properties of peptide hydrogels. Incorporation of a 1, 4, 5, 8-Napthalene tetracarboxylic diimide (NDI) and a dipeptide in the imide position, we found the composition of the peptides can determine the strength and gelation of this type of hydrogels. The four compounds are presented in the study (C8NDI-FF, C8NDI-FG, C8NDI-GF and C8NDI-GG) whic
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MANIVANNAN, KARTHIKEYAN, and KARTHIKEYAN MANIVANNAN. "Hybrid Core-Shell Micro-Nanospheres for Sensing, Bioimaging and Photothermal Therapy Applications." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/83dn97.

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博士<br>國立臺灣科技大學<br>材料科學與工程系<br>106<br>This PhD research mainly focused on the spherical-shape core-shell SiO2-poly(N isopropylacrylamide) (PNIPAM) and Ag@SiO2@Ag micro-nanosphere hybrid core-shell micronanospheres for sensing, biomedical applications due to its attracting physicochemical property. due to high mobility and good dispersion properties in paste state, high packing density and low light scattering, high surface area, good biocompatibility.These doctoral studies divided in to three applications such as photonic crystals (PCs), sensor and bioimaging (BI), Photothermal therapy (PTT). F
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Lan, Li Hsuan, and 藍立璿. "Silver sulfide quantum dot syntheses by microfluidic reaction and its applications in bioimaging." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/ar9866.

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Charan, Shobhit, and 休伯西. "Development and Surface Engineering of Nanomaterials for Cellular Uptake, Localized Targeting and Bioimaging Applications." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/98281667604357342015.

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博士<br>國立臺灣大學<br>化學研究所<br>100<br>During the past few decades, fluorescence microscopy has been a powerful technique in the field of cell biology for imaging cellular structures with single molecular sensitivity. However, the fluorescence signals do not provide detailed molecular information, and the photo-bleaching effect often limits their applications. A lot of research efforts have been carried out to synthesize new materials to overcome these limitations. Recently, sensitive optical imaging technology using metal nanoparticles has been extensively used for many cellular and biomedical appl
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Liu, Chih-Wei, and 劉智偉. "The Study of Vibrio vulnificus Blue Fluorescent Protein Applications for Gram Negative Bacteria Bioimaging System." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/27077609491115446733.

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碩士<br>國立成功大學<br>化學工程學系碩博士班<br>93<br>The expression of the wild type (bfp) and mutation gene (bfp-D7) of blue fluorescent protein (BFP) isolated from Vibrio vulnificus CKM-1 in the giant protoplasts of Escherichia coli XL1B and V. vulnificus CKM-1 were investigated, respectively. In addition, the method for quantifying of the fluorescent intensity of BFP by fluorescent microscopy as well as digital camera was illustrated. The results first showed that both the protoplasts of E. coli and V. vulnificus were able to express bfp as well as bfp-D7, indicating that giant protoplasts possess cell fu
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Lin, Wei-shiang, and 林偉翔. "Preparation and Surface Functionalization of Zn-CuInS2 Quantum Dots for Bioimaging and Anticancer Drug Delivery Applications." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/13086755707927437813.

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碩士<br>國立臺灣科技大學<br>化學工程系<br>102<br>In this research, we investigate the synthesis process of quantum dots and its biomedical applications on cell imaging along with delivering anticancer drug. In the beginning, we directly synthesize water-soluble Zn-CuInS2 quantum dots (ZCIS QDs) facilitated by polyacrylic acid and L-glutathione as stabilizing and reactivity-controlling agents. The optimization of copper, indium and zinc ratio to improve the quantum yields of ZCIS QDs also become important part to be improved on this research. Moreover, by ZnS coating on the surface of ZCIS QDs, the quantum
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Zhang, Ran. "Biocompatible plasmonic nanostructures for bio-imaging applications and novel functional plasmonic materials." Thesis, 2018. https://hdl.handle.net/2144/30727.

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Our work addresses a novel biocompatible plasmon-enhanced nanostructure approach based on the combination of metal nanoparticles, light emitting polymer-based nanostructures, and scalable cellulose nanofiber templates via a one-step facile electrospinning process that can easily be applied to biomedical devices. In collaboration with the Team of Prof. Lee Goldstein in the Boston University medical campus, we demonstrated light emission from small-size (below 200nm) polymer nanoparticles coupled to plasmonic nanoparticles and to light-emitting biocompatible molecules. In order to fully demonstr
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M, Vedamalai, and 馬惟達. "Fluorescent Sensors for Reactive Oxygen Species and Metal Ions Based on Organic Dyes and Their Applications in Bioimaging." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/32910955390827035299.

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博士<br>國立交通大學<br>應用化學系碩博士班<br>101<br>Abstract Organic compounds have been used extensively to construct photo luminescent materials, solar cells and chemosensors. Its significance can be attributed to easy synthesis, inexpensive staring materials, easy to tune photo physical properties and easy to link with other supporting materials. Fluorescence sensing is a process in which interaction between species is detected by change in the fluorescence intensity of system. Organic dyes are ideally suited to be used as probes for fluorescence sensing. This work therefore is focused on synthesis of orga
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Panthani, Matthew George. "Colloidal nanocrystals with near-infrared optical properties : synthesis, characterization, and applications." 2011. http://hdl.handle.net/2152/19825.

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Colloidal nanocrystals with optical properties in the near-infrared (NIR) are of interest for many applications such as photovoltaic (PV) energy conversion, bioimaging, and therapeutics. For PVs and other electronic devices, challenges in using colloidal nanomaterials often deal with the surfaces. Because of the high surface-to-volume ratio of small nanocrystals, surfaces and interfaces play an enhanced role in the properties of nanocrystal films and devices. Organic ligand-capped CuInSe2 (CIS) and Cu(InXGa1-X)Se2 (CIGS) nanocrystals were synthesized and used as the absorber layer in proto
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