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1

Howell, Seth, Marlon Rampaul, Divya Ahuja, and Joseph Horvath. "Danger of Biologic Therapy with Unrecognized Human T-cell Lymphotrophic Virus 1 (HTLV-1)." Open Forum Infectious Diseases 4, suppl_1 (2017): S724—S725. http://dx.doi.org/10.1093/ofid/ofx163.1954.

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2

Skupsky, Jonathan, and David W. Scott. "Immunogenicity of Factor VIII: Is Clotting the “Danger” Signal?." Blood 110, no. 11 (2007): 2685. http://dx.doi.org/10.1182/blood.v110.11.2685.2685.

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Abstract It is well established that mice lacking factor VIII (E16 or fVIII−/−) respond to intravenous (i.v.) or intraperitoneal (i.p.) injections of therapeutic doses of human fVIII in PBS. This leads to both T-cell priming for cytokine production and inhibitor formation against fVIII with specificity similar to that of hemophilia A patients (Pratt et al., 2004). The lack of tolerance to murine fVIII may be important in the ability of fVIII−/− mice to respond to human fVIII. Nonetheless, the ability to respond effectively in the absence of extrinsic adjuvant begs the question of what is the “
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3

Dianova, Dina G., Oleg V. Dolgikh, Inga N. Alikina, and Yuliya A. Chelakova. "Analysis of cell death indicators in employees under exposure to phenol at work." Occupational Health and Industrial Ecology, no. 10 (February 18, 2019): 62–64. http://dx.doi.org/10.31089/1026-9428-2018-10-62-64.

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For early diagnosis of health disorders in workers exposed to excessive levels of phenol, the authors identified parameters of immune state, characterizing apoptosis of immune cells. The identification used contemporary method of laboratory immunologic studies including flow cytometry. Findings are that biologic media highly contaminated with phenol demonstrate statistically significant (twice; p < 0.05) decrease of transcription factor p53 expression and TNFRI cells count, as well as 1.2 times lower percentage of apoptosis-associated Annexin V-FITC+7-AAD- cells — that characterizes a cours
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4

Samelko, Lauryn, Marco Caicedo, Kyron McAllister, Joshua Jacobs, and Nadim James Hallab. "Metal-induced delayed type hypersensitivity responses potentiate particle induced osteolysis in a sex and age dependent manner." PLOS ONE 16, no. 5 (2021): e0251885. http://dx.doi.org/10.1371/journal.pone.0251885.

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It is widely recognized that innate macrophage immune reactions to implant debris are central to the inflammatory responses that drive biologic implant failure over the long term. Less common, adaptive lymphocyte immune reactions to implant debris, such as delayed type hypersensitivity (DTH), can also affect implant performance. It is unknown which key patient factors, if any, mediate these adaptive immune responses that potentiate particle/macrophage mediated osteolysis. The objective of this investigation was to determine to what degree known adaptive immune responses to metal implant debris
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5

Leru, Polliana Mihaela, Ana-Maria Eftimie, Vlad Florin Anton, and Michel Thibaudon. "Five-Year Data on Pollen Monitoring, Distribution and Health Impact of Allergenic Plants in Bucharest and the Southeastern Region of Romania." Medicina 55, no. 5 (2019): 140. http://dx.doi.org/10.3390/medicina55050140.

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Background and objectives: Respiratory allergies induced by allergenic pollen represent an important public health problem with increasing prevalence and severity in Europe. Romania has no aerobiology network and pollen measurements have been done for about ten years in the west region only. Materials and Methods: We established the first pollen monitoring center in the capital of Bucharest in 2013, based on collaboration with the Réseau National de Surveillance Aérobiologique (RNSA) from France. The aim of our paper is to present results from five years of pollen monitoring in the city center
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6

Wasser, Berchthold, and Bernhard Perren. "Wirkung von Schutzwald gegen gravitative Naturgefahren – Protect-Bio." Schweizerische Zeitschrift fur Forstwesen 165, no. 9 (2014): 275–83. http://dx.doi.org/10.3188/szf.2014.0275.

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Effect of protection forests on natural hazards due to gravity: Protect-Bio The “Protect-Bio” project of the Federal Environment Agency aims to appraise the effects of biological protection measures, notably protection forests, in such a way that they can be compared to the effects of technical protection measures with the same objectives. A methodology has been developed in the context of the “Protect” project of the National Platform for Natural Hazards (PLANAT) to assess technical measures, which has several stages: preparation, rapid assessment, evaluation of measures, evaluation of effect
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7

Ivanovic, S., I. Pavlovic, M. Zujovic, Z. Tomic, and N. Memisi. "Bacteria in goat meat: Biological danger." Biotehnologija u stocarstvu 27, no. 3 (2011): 1185–92. http://dx.doi.org/10.2298/bah1103185i.

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In the world, especially in China, India, P?kist?n and Nigeria goat meat represents an important foodstuff in nutrition of people. Goat meat is being increasingly consumed in Serbia owing to its distinctive taste and desirable chemical composition. As many other types of meat, goat meat can be the source of pathogenic bacteria. Bacteria can find their way into meat of healthy goats or goats with no clinical symptoms premortally (infection) or postmortally (contamination). For these reasons EU has included in its programme of monitoring zoonosis and zoonotic agents? microbiological pathogens wh
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8

Balykova, L. A., D. O. Vladimirov, A. V. Krasnopolskaya, O. M. Soldatov, N. V. Ivyanskaya, and N. V. Shchekina. "CARDIOVASCULAR SYSTEM DAMAGE IN CHILDREN WITH COVID-19." Pediatria. Journal named after G.N. Speransky 100, no. 5 (2021): 90–98. http://dx.doi.org/10.24110/0031-403x-2021-100-5-90-98.

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Coronavirus infection poses a particular danger in relation to decompensation of existing chronic diseases and specific damage to the cardiovascular system (CVS) both during an acute infection and during convalescence. Objective of the study: to summarize current knowledge about the potential involvement of CVS in the development and progression of acute COVID-19 infection and multisystem inflammatory syndrome (MIS) in children and to form an sense of the predictive value, diagnostic tactics and treatment of cardiac anomalies during the coronavirus pandemic. A search was performed in MEDLINE,
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9

Leventhal, Howard. "The Dangers of Biological Testing." Contemporary Psychology: A Journal of Reviews 36, no. 3 (1991): 213–14. http://dx.doi.org/10.1037/029514.

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10

Golkar, Armita, Vasco Castro, and Andreas Olsson. "Social learning of fear and safety is determined by the demonstrator's racial group." Biology Letters 11, no. 1 (2015): 20140817. http://dx.doi.org/10.1098/rsbl.2014.0817.

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Social learning offers an efficient route through which humans and other animals learn about potential dangers in the environment. Such learning inherently relies on the transmission of social information and should imply selectivity in what to learn from whom . Here, we conducted two observational learning experiments to assess how humans learn about danger and safety from members (‘demonstrators') of an other social group than their own. We show that both fear and safety learning from a racial in-group demonstrator was more potent than learning from a racial out-group demonstrator.
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11

Chan, Christopher K. Y., Christopher R. Holroyd, Alice Mason, Jalaa Zarroug, and Christopher J. Edwards. "Are there dangers in biologic dose reduction strategies?" Autoimmunity Reviews 15, no. 7 (2016): 742–46. http://dx.doi.org/10.1016/j.autrev.2016.03.013.

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12

Wong, W. "Crystalline Danger Signal." Science Signaling 3, no. 120 (2010): ec129-ec129. http://dx.doi.org/10.1126/scisignal.3120ec129.

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13

Pedley, Robert, and Andrew P. Gilmore. "Mitosis and mitochondrial priming for apoptosis." Biological Chemistry 397, no. 7 (2016): 595–605. http://dx.doi.org/10.1515/hsz-2016-0134.

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Abstract Cell division is a period of danger for cells, as inaccurate segregation of chromosomes can lead to loss of cell viability or aneuploidy. In order to protect against these dangers, cells ultimately initiate mitochondrial apoptosis if they are unable to correctly exit mitosis. A number of important chemotherapeutics exploit this response to delayed mitotic exit, but despite this, the molecular mechanism of the apoptotic timer in mitosis has proved elusive. Some recent studies have now shed light on this, showing how passage through the cell cycle fine-tunes a cell’s apoptotic sensitivi
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14

Mazza, Marianna, Giuseppe Marano, Carlo Lai, Luigi Janiri, and Gabriele Sani. "Danger in danger: Interpersonal violence during COVID-19 quarantine." Psychiatry Research 289 (July 2020): 113046. http://dx.doi.org/10.1016/j.psychres.2020.113046.

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15

Flintoft, Louisa. "Danger! Uncertain alignments!" Nature Reviews Genetics 9, no. 3 (2008): 162. http://dx.doi.org/10.1038/nrg2327.

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16

Berry, Colin. "The dangers of hazards." Toxicology Research 5, no. 2 (2016): 373–76. http://dx.doi.org/10.1039/c5tx00472a.

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17

Kowalczyk, Dariusz W. "Tumors and the danger model." Acta Biochimica Polonica 49, no. 2 (2002): 295–302. http://dx.doi.org/10.18388/abp.2002_3787.

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This article reviews the evidence for the danger model in the context of immune response to tumors and the insufficiency of the immune system to eliminate tumor growth. Despite their potential immunogenicity tumors do not induce significant immune responses which could destroy malignant cells. According to the danger model, the immune surveillance system fails to detect tumor antigens because transformed cells do not send any danger signals which could activate dendritic cells and initiate an immune response. Instead, tumor cells or antigen presenting cells turn off the responding T cells and
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18

D. Wisman, Jon. "9/11, foreign threats, political legitimacy, and democratic institutions." Humanomics 30, no. 1 (2014): 22–40. http://dx.doi.org/10.1108/h-12-2013-0078.

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Purpose – The manipulation of fears generated by 9/11 resulted in restrictions of civil liberties. Although this danger to freedom has been descriptively addressed, its deeper causes and dynamics have not received extensive treatment. This article reassesses the political reaction to 9/11 in terms of economic theory and evolutionary biology. The paper aims to discuss these issues. Design/methodology/approach – The explanatory framework is drawn from findings in the economics of war and the biological evolution of war-like behavior in the human species. Findings – The fact that war and its thre
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19

Lipscomb, Mary F., and Barbara J. Masten. "Dendritic Cells: Immune Regulators in Health and Disease." Physiological Reviews 82, no. 1 (2002): 97–130. http://dx.doi.org/10.1152/physrev.00023.2001.

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Dendritic cells (DCs) are bone marrow-derived cells of both lymphoid and myeloid stem cell origin that populate all lymphoid organs including the thymus, spleen, and lymph nodes, as well as nearly all nonlymphoid tissues and organs. Although DCs are a moderately diverse set of cells, they all have potent antigen-presenting capacity for stimulating naive, memory, and effector T cells. DCs are members of the innate immune system in that they can respond to dangers in the host environment by immediately generating protective cytokines. Most important, immature DCs respond to danger signals in the
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20

Hwang, Paul F., Nancy Porterfield, Dylan Pannell, Thomas A. Davis, and Eric A. Elster. "Trauma is danger." Journal of Translational Medicine 9, no. 1 (2011): 92. http://dx.doi.org/10.1186/1479-5876-9-92.

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21

Jagielska, Beata, Patrycja Ozdowska, Katarzyna Gepner, et al. "Cardiotoxicity danger in immunotherapy." IUBMB Life 72, no. 6 (2020): 1160–67. http://dx.doi.org/10.1002/iub.2299.

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22

Benning, Tony B. "Ethnicity and Cognition: Dangers of Biological Determinism." Journal of Neuropsychiatry and Clinical Neurosciences 20, no. 1 (2008): 120–21. http://dx.doi.org/10.1176/jnp.2008.20.1.120.

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23

Sarig, S., R. Azoury, and N. Garti. "Biological Control to Diminish Dangers of Urolithiasis." Urologia Internationalis 40, no. 5 (1985): 274–76. http://dx.doi.org/10.1159/000281098.

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24

Gross, Michael. "Coffee and chocolate in danger." Current Biology 24, no. 11 (2014): R503—R506. http://dx.doi.org/10.1016/j.cub.2014.05.035.

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25

Bird, H. A., and A. Bergstrom. "A dancer with rheumatoid arthritis: a role for biologics." Clinical Rheumatology 32, no. 4 (2013): 507–9. http://dx.doi.org/10.1007/s10067-013-2201-y.

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26

Klarsfeld, A., and P. Vernier. "La biologie au service de l'antiracisme : limites et dangers." médecine/sciences 14, no. 11 (1998): 1292. http://dx.doi.org/10.4267/10608/961.

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27

Klune, John R., Rajeev Dhupar, Jon Cardinal, Timothy R. Billiar, and Allan Tsung. "HMGB1: Endogenous Danger Signaling." Molecular Medicine 14, no. 7-8 (2008): 476–84. http://dx.doi.org/10.2119/2008-00034.klune.

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28

Tarazona, JoséVicente. "The identification of thresholds of acceptability and danger: The biological route." Toxicology Letters 88 (October 1996): 4. http://dx.doi.org/10.1016/s0378-4274(96)80011-7.

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29

Gabaraev, B. A., I. Kh Ganev, and A. V. Lopatkin. "Potential Biological Danger of Uranium Used in the Nuclear Fuel Cycle." Atomic Energy 96, no. 6 (2004): 422–29. http://dx.doi.org/10.1023/b:aten.0000041211.48569.2f.

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30

Hadland, Brandon K., and Gregory D. Longmore. "Erythroid-Stimulating Agents in Cancer Therapy: Potential Dangers and Biologic Mechanisms." Journal of Clinical Oncology 27, no. 25 (2009): 4217–26. http://dx.doi.org/10.1200/jco.2008.21.6945.

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Erythropoietin-stimulating agents (ESAs) were originally designed to replace endogenous erythropoietin in patients with anemia secondary to renal failure. Their use has subsequently been expanded to include patients with anemia of other causes, including cancer patients, in whom deficiency of erythropoietin, per se, is not the primary cause of anemia. Although early studies showed promise of ESA administration in reducing the need for transfusions and improving the quality of life in cancer patients, several large randomized clinical trials have recently shown a potential detrimental effect of
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31

Broggi, Achille, and Francesca Granucci. "Microbe- and danger-induced inflammation." Molecular Immunology 63, no. 2 (2015): 127–33. http://dx.doi.org/10.1016/j.molimm.2014.06.037.

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32

Frantz, Stefan, Claudia Monaco, and Fatih Arslan. "Danger Signals in Cardiovascular Disease." Mediators of Inflammation 2014 (2014): 1–2. http://dx.doi.org/10.1155/2014/395278.

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33

Williams, Nigel. "Sperm dangers." Current Biology 15, no. 3 (2005): R77. http://dx.doi.org/10.1016/j.cub.2005.01.018.

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34

Michailiuk, Bogdan. "Threat of biological weapons." Securitologia 23, no. 1 (2016): 59–75. http://dx.doi.org/10.5604/01.3001.0009.2969.

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The biological weapons often is defined as ‘weapons of mass destruction poor’, because this is relatively cheap and easy in the production, hidden and relocation. The risk of the use biological weapons still seems to be very real. A possibility of using weapons of mass destruction (biological weapon) is arousing special danger by contemporary terrorist organizations. In this article in a synthetic, based on the available references and the unpublished information, author present the current level of threat of biological terrorism.
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35

Ash, C. "Digoxin Dangers." Science Signaling 6, no. 285 (2013): ec172-ec172. http://dx.doi.org/10.1126/scisignal.2004529.

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36

Srinivasan, Mandyam V. "Honeybee Communication: A Signal for Danger." Current Biology 20, no. 8 (2010): R366—R368. http://dx.doi.org/10.1016/j.cub.2010.02.051.

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37

Andrews, Norma W. "Membrane repair and immunological danger." EMBO reports 6, no. 9 (2005): 826–30. http://dx.doi.org/10.1038/sj.embor.7400505.

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38

Harris, Helena Erlandsson, and Angela Raucci. "Alarmin(g) news about danger." EMBO reports 7, no. 8 (2006): 774–78. http://dx.doi.org/10.1038/sj.embor.7400759.

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39

Benaderette, Serge. "La médicalisation de la biologie, un impératif contre le danger de la financiarisation." Option/Bio 20, no. 420 (2009): 1–3. http://dx.doi.org/10.1016/s0992-5945(09)70154-0.

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40

Turco, Vincent J., and Anthony J. Spinella. "Achilles Tendon Ruptures—Peroneus Brevis Transfer." Foot & Ankle 7, no. 4 (1987): 253–59. http://dx.doi.org/10.1177/107110078700700407.

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Peroneus brevis tendon transfer has been utilized in 40 individuals during the last 13 years. All cases consisted of complete Achilles tendon ruptures. In 34 cases the rupture was in the distal one-third of the tendon substance, in four cases bony avulsion of the calcaneal tuberosity occurred, and in two cases there was a diffuse tear in the proximal two-thirds of the tendon near the musculotendinous junction. The middle-aged athlete sustained the majority of these injuries during sports. Eleven patients were less than 30 years old, 23 patients were 30 to 40 years old, and six were over 40 yea
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41

Krishnan, S. "Manhole Workers Dodge Danger Down Under." International Journal of Emerging Research in Management and Technology 7, no. 5 (2018): 25. http://dx.doi.org/10.23956/ijermt.v7i5.37.

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We hold our breath, close our eyes and move on with the job to dislodge the block. It is not easy to enter the dark drain and we are trapped inside for hours at times. This is just one harrowing tale of any sanitary workers in any part of the country.” There are many more awaiting to be told and heard. The manholes, which these workers deal upon, are poisonous gas chambers and as if working under such inhumane conditions is not enough, there are serious safety issues cropping up. With no safety equipments provided, the workers descend into the manhole. The occupational exposures of sewage work
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42

Demetrian, Alin Dragos, Mihnea Cosmin Costoiu, Augustin Semenescu, et al. "On the Reduction of the Biological Danger of Environmental Contamination by Using a “Complete and Reusable Thoracic Drainage System”." Sustainability 11, no. 10 (2019): 2873. http://dx.doi.org/10.3390/su11102873.

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A clean environment is essential for human health and well-being. A significant share of total waste is represented by hospital waste that is produced in increasing quantities by sanitary units, with the appearance of the disposable tools. Taking into account the unfavourable environmental impact, the biological danger that this waste represents, and the restrictive legislation imposed by the European Union, urgent measures are needed to reduce their quantities. In this regard, the paper refers to the design of a completely reusable thoracic drainage system and to the positive implications tha
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43

Sorci, Guglielmo, Gloria Giovannini, Francesca Riuzzi, et al. "The Danger Signal S100B Integrates Pathogen– and Danger–Sensing Pathways to Restrain Inflammation." PLoS Pathogens 7, no. 3 (2011): e1001315. http://dx.doi.org/10.1371/journal.ppat.1001315.

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44

Burgess, Darren J. "Double danger from mitochondrial mutations." Nature Reviews Genetics 14, no. 10 (2013): 678–79. http://dx.doi.org/10.1038/nrg3581.

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45

Dyatlov, I. A., L. I. Marinin, N. A. Shishkova, A. N. Mokrievich, and E. A. Tyurin. "The danger of anthrax soil foci during excavation." Bacteriology 5, no. 4 (2020): 12–19. http://dx.doi.org/10.20953/2500-1027-2020-4-12-19.

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The anthrax pathogen trapped in the soil forms spores that retain their viability and virulence for a long time. Analysis of the available data shows that the anthrax microbe can retain virulence in soil up to 1300 years. All this time, the soil remains dangerous for people during earthworks on the territory of anthrax soil foci. Soil foci of anthrax include anthrax burial grounds (burials), places of death, sites, spontaneous burials of animals killed by anthrax and other environmental objects containing the causative agent of anthrax. Under favorable conditions, the pathogen, being in the so
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46

Wells, William A. "With Aβ, the danger lies within". Journal of Cell Biology 156, № 3 (2002): 411. http://dx.doi.org/10.1083/jcb1563iti1.

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47

Knight, Kathryn. "Cuttlefish hear looming danger." Journal of Experimental Biology 221, no. 1 (2018): jeb174219. http://dx.doi.org/10.1242/jeb.174219.

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48

HENRY, JULIE D., COURTNEY VON HIPPEL, TED RUFFMAN, YAEL PERRY, and PETER G. RENDELL. "Threat perception in schizophrenia-spectrum disorders." Journal of the International Neuropsychological Society 16, no. 5 (2010): 805–12. http://dx.doi.org/10.1017/s1355617710000640.

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AbstractIt has been suggested that, relative to the other basic emotions, the perception of threat-related emotion is disproportionately impaired in schizophrenia-spectrum disorders. Yet research has not assessed how schizophrenia-spectrum disorders affect the ability to make direct appraisals of threat. In the present study, participants with schizophrenia spectrum disorders were compared with controls on two danger rating tasks that involved differentiating between faces and situations normatively judged to be either high or low in threat. It was also assessed whether danger ratings were rel
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49

Robbins, Marjorie A., and John J. Rossi. "Sensing the danger in RNA." Nature Medicine 11, no. 3 (2005): 250–51. http://dx.doi.org/10.1038/nm0305-250.

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50

Philippe, Pierre. "La recherche médicale en danger." médecine/sciences 23, no. 6-7 (2007): 652–54. http://dx.doi.org/10.1051/medsci/20072367652.

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