Relevant bibliographies by topics / Biological active compounds

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Biological active compounds'

Author: Grafiati
Published: 4 June 2021
Last updated: 14 February 2022

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Journal articles on the topic "Biological active compounds"

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Novruzov, E. N. "Biologically Active Compounds and Biological Activity of Physalis alkekengi (Solanaceae)." Растительные ресурсы 56, no. 3 (2020): 280–88. http://dx.doi.org/10.31857/s0033994620020077.

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Savchuk, Ya I., K. S. Tsyhanenko, O. V. Andrienko, and I. M. Kurchenko. "The New Biologically Active Metabolites from Aspergillus niveus 2411." Mikrobiolohichnyi Zhurnal 83, no. 4 (August 17, 2021): 74–85. http://dx.doi.org/10.15407/microbiolj83.04.074.

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Pharmacological science possesses a significant number of compounds with antibiotic activity. By now the chemical structures have been identified and their properties have been described for the great number; many of them found practical use. But the main stimulus for the further new antibiotic compounds search is the acquired resistance of pathogenic organisms. Our previous investigations were devoted to antibiotic activity of Aspergillus niveus that is known as a producer of ferment preparations with wide activity spectrum. Aim. This investigation became the follow-up of our previous studies and its main task was to isolate, purify and obtain biologically active metabolite(s) from A. niveus 2411 strain in crystalline form, and to study its (their) physicochemical properties and biological activity. Methods. Biologically active metabolites were obtained by extraction, two-step column chromatography and recrystallization methods. The obtained substances were characterized by physical-chemical and microbiological methods. Results. Two substances in crystalline form with different spectrum of antibiotic activity against indicator test-cultures were obtained. The substance AN4 showed antibacterial, antifungal, and phytotoxic activities, while AN7 showed only antibacterial activity. Neither of obtained compounds showed dermatocidal or toxigenic activity in rabbit skin test. Obtained spectral characteristics of substances suggest that AN4 and AN7 substances are similar and belong to compounds with cyclic structures, have double linkage, methyl, aromatic, and carboxyl groups. Conclusions. Obtained data showed that antibiotic activity of A. niveus 2411 depend on the complex of biologically active metabolites with different biological and physicochemical properties. Two compounds AN4 and AN7 were isolated and purified from the fungal cultural filtrate of A. niveus 2411. The data of IR and UV spectra of these compounds and their profiles of biological activity don’t have significant differences with those of citrinin – a metabolite of A. niveus with antibiotic properties. However, based on the results obtained and comparisons with the data of other authors on metabolites of A. niveus, we suggest that the substances we isolated may be derivatives of citrinin.
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Poljakovic, Melita, Majda Srabovic, and Ekrem Pehlic. "Synthesis and Morphology of Biological Active Compounds." Journal of Scientific Research and Reports 3, no. 19 (January 10, 2014): 2562–73. http://dx.doi.org/10.9734/jsrr/2014/12033.

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Dang, Nga Phuong, Bjarne Landfald, and Nils Peder Willassen. "Biological surface-active compounds from marine bacteria." Environmental Technology 37, no. 9 (November 2, 2015): 1151–58. http://dx.doi.org/10.1080/09593330.2015.1103784.

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Ježek, Jan, Milan Zaoral, Miloš Buděšínský, Jiří Günther, and Jiří Rotta. "Muramyl-dipeptide analogues: Synthesis and biological activities." Collection of Czechoslovak Chemical Communications 53, no. 11 (1988): 2897–906. http://dx.doi.org/10.1135/cccc19882897.

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In the search for immunoadjuvant active compounds without pyrogenic activity we prepared N-Ac-norMur-L-Abu-D-Gln-O-Bu (V), N-Ac-Mur-L-Abu-D-Gln-O-Bu (VII) and their respective α-benzylglycosides VI and VIII. All the prepared compounds are nonpyrogenic. In the delayed hypersensitivity test, compound V is inactive, VI is comparable to MDP, VII is more and VIII is less active than MDP.
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Plackal George, Blassan, Parimelazhagan Thangaraj, Cheruthazhakkatt Sulaiman, Shanmughavel Piramanayagam, and Sathish Kumar Ramaswamy. "Bioassay Directed Isolation and Biological Evaluation of Compounds Isolated fromRubus fairholmianusGard." BioMed Research International 2014 (2014): 1–15. http://dx.doi.org/10.1155/2014/204340.

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Thein vitroandin silicoanalysis ofRubus fairholmianusacetone extract for antioxidant, antiproliferative, and anti-inflammatory activity led to the isolation of six compounds. Amongst all the six isolated compounds tested, 1-(2-hydroxyphenyl)-4-methylpentan-1-one (compound1) and 2-[(3-methylbutoxy) carbonyl] benzoic acid (compound2) were found to be more active in inhibiting BRCA and COX target proteins, which also showed the better results for DPPH and ABTS radical scavenging assays. The promising results of this investigation emphasize the importance of usingR. fairholmianusin the treatment of radical generated disorders mainly cancer and other inflammatory diseases.
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Appell, Kenneth C., Thomas D. Y. Chung, Michael J. H. Ohlmeyer, Nolan H. Sigal, John J. Baldwin, and Daniel Chelsky. "Biological Screening of a Large Combinatorial Library." Journal of Biomolecular Screening 1, no. 1 (February 1996): 27–31. http://dx.doi.org/10.1177/108705719600100111.

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Encoding technology has allowed for the creation of libraries of 50,000 or more low-molecular-weight compounds for biological testing. The current challenge is to properly and efficiently screen among these compounds for useful biological activities. In this example, actives against two related G-protein coupled receptors were sought from a combinatorial library of 56,000 members. The library was synthesized on solid phase using the split synthesis method and photochemically released for testing. At a screening concentration of 0.5-1 /LM, 86 unique structures were identified as active against one receptor and 24 were active against the other. Due to the random nature of compound sampling, five library equivalents or 280,000 beads were screened to ensure greater than 99% representation of library members. As a result, many actives appeared multiple times in the screen, verifying the encoding process. Further confirmation was obtained by resynthesis and testing of predicted active structures. A clear bias for specific "R" groups at each point of variation in the combinatorial library with little overlap between the two receptors has produced a clear structure-activity relationship on which to base further work.
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Asakawa, Yoshinori. "Biologically active compounds from bryophytes." Pure and Applied Chemistry 79, no. 4 (January 1, 2007): 557–80. http://dx.doi.org/10.1351/pac200779040557.

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Liverworts produce a great variety of lipophilic terpenoids, aromatic compounds, and acetogenins. Many of these constituents have characteristic scents, pungency, and bitterness, and display a quite extraordinary array of bioactivities and medicinal properties. These expressions of biological activity are summarized and discussed, and examples are given of the potential of certain lead compounds for structure-activity studies and synthesis.
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Khan, Khalid M., Zafar S. Saifyb, Abdullah Khan, Mansoor Ahmed, Muhammed Saeed, Raid J. Abdel-Jalil, Gerald Griibler, and Wolfgang Voelter. "Syntheses of Selected Quaternary Phenacylbromopyridinium Compounds and their Biological Evaluation." Zeitschrift für Naturforschung B 54, no. 9 (September 1, 1999): 1210–18. http://dx.doi.org/10.1515/znb-1999-0920.

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The studies, presented here, deal with the synthetic modification of 5-bromonicotinic acid on its nitrogen nucleus. The synthetic transformations were carried out by reacting equimolar amounts of 5-bromonicotinic acid and phenacyl halides in acetone. A range of phenacyl halides were used with the objective of getting a variety of quaternary ammonium salts of 5- bromonicotinic acid derivatives as multipurpose biologically active compounds. Twelve quaternary ammonium salts of 5-bromonicotinic acid have been synthesized and tested for cytotoxicity, antibacterial and antifungal activities. These compounds showed promising cytotoxicity against Artemia salina. Two compounds, 3-carboxy-1-(4′-methylphenacyl)-5-bromopyridinium bromide (2) and 3-carboxy-1-(4′-nitrophenacyl)-5-bromopyridinium bromide (12), were highly active against Gram-positive and Gram-negative bacteria among all the tested compounds. All the compounds were examined for antifungal activity against fifteen fungal cultures, but none of these compounds proved to be effective against these fungi. The parent compounds and its derivatives were also examined for their effect on mean arterial blood pressure in anaesthetized rats. Compounds 7 and 8 were found to be twofold more active than the parent compound. The rest of the products showed blood pressure lowering effects comparable to the parent compound. All compounds were characterised via elemental analysis UV, IR , mass and 1H NMR spectroscopy.
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Mourad, mohamed. "BIOLOGICAL STUDIES ON ACTIVE COMPOUNDS FROM TRICHODERMA VIRIDE." Al-Azhar Journal of Pharmaceutical Sciences 53, no. 1 (March 1, 2016): 143–59. http://dx.doi.org/10.21608/ajps.2016.6895.

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Dissertations / Theses on the topic "Biological active compounds"

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Mohamadi, Shahrzad. "Electrochemical screening of biological membrane active compounds." Thesis, University of Leeds, 2014. http://etheses.whiterose.ac.uk/8619/.

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Interactions of biomembrane-active compounds with phospholipid monolayers on microfabricated Pt/Hg electrodes in an on-line high throughput flow system are demonstrated by recording capacitance current peak changes in rapid cyclic voltammograms (RCV). Detection limits of the compounds' effects on the layer have been estimated from the data. Compounds studied include steroids, polycyclic aromatic hydrocarbons, tricyclic antidepressants, tricyclic phenothiazines pyridinium compounds, spiperone and spiperone analogues and a range of serotonin and dopamine receptor ligands. The results show that the extent and type of interaction depends on the: - (a) presence and number of aromatic rings and substituents, (b) presence and composition of side chains and, (c) molecular shape. Interaction is only indirectly related to compound hydrophobicity. For a selection of tricyclic antidepressants and tricyclic phenothiazines the detection limit in water is related to their therapeutic normal threshold. The sensing assay has been tested in the presence of humic acid as a potential interferent and in a tap water matrix. It was subsequently tested in a natural water matrix. The system can be applied to the screening of putative hazardous substances allowing for early detection thereof in the water supply. The measurements are made in real time which means that potentially toxic compounds are detected rapidly in <10 minutes per assay. This technology will contribute greatly to environment safety and health.
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Esmati, Nasim. "Synthesis of Biologically Active Compounds via Multicomponent Reactions and Evaluation of Their Biological Activities." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1525897360405194.

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Boukes, Gerhardt Johannes. "The in vitro biological activities of three Hypoxis species and their active compounds." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/1228.

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The African potato is used as an African traditional medicine for its nutritional and medicinal properties. Most research has been carried out on H. hemerocallidea, with very little or nothing on other Hypoxis spp. The main aim of this project was to provide scientific data on the anticancer, anti-inflammatory and antioxidant properties of H. hemerocallidea, H. stellipilis and H. sobolifera chloroform extracts and their active compounds. The hypoxoside and phytosterol contents of the three Hypoxis spp. were determined using TLC, HPLC and GC. H. hemerocallidea and H. sobolifera chloroform extracts contained the highest amounts of hypoxoside and β-sitosterol, respectively. For the anticancer properties, cytotoxicity of the Hypoxis extracts and its purified compounds were determined against the HeLa, HT-29 and MCF-7 cancer cell lines (using MTT), and PBMCs (using CellTiter-Blue®). H. sobolifera had the best cytotoxicity against the three cancer cell lines, whereas H. stellipilis stimulated HeLa and HT-29 cancer cell growth. IC50 values of hypoxoside and rooperol were determined. DNA cell cycle arrest (using PI staining) occurred in the late G1/early S (confirmed by increased p21Waf1/Cip1 expression) and G2/M phases after 15 and 48 hrs, respectively, when treated with Hypoxis extracts and rooperol. H. sobolifera and rooperol activated caspase-3 and -7 (using fluorescently labelled antibodies) in HeLa and HT-29 cancer cells, and caspase-7 in MCF-7 cancer cells after 48 hrs. Annexin V binding to phosphatidylserines in rooperol treated U937 cells confirmed early apoptosis after 15 hrs. The TUNEL assay showed DNA fragmentation in the three cancer cell lines when treated with H. sobolifera and rooperol for 48 hrs. A shift pass the G2/M phase has led to the investigation of endoreduplication, which was confirmed by cell/nucleus size, and anti-apoptotic proteins (Akt, phospho-Akt, phospho-Bcl-2 and p21Waf1/Cip1). U937 cell differentiation to monocyte-macrophages was optimized using PMA and 1,25(OH)2D3, which was confirmed by morphological and biochemical changes. For the anti-inflammatory properties, Hypoxis extracts and rooperol significantly increased NO production in monocyte-macrophages (pre-loaded with DAF-2 DA) and phagocytosis of pHrodoTM E. coli BioParticles®. The treatments had no effect on COX-2 expression in monocyte-macrophages. The phytosterols significantly increased IL-1β and IL-6 secretion xv (using the FlowCytomix Multiplex human Th1/Th2 10plex Kit I) in the PBMCs of one donor. For the antioxidant properties, Hypoxis extracts and rooperol significantly increased ROS production in undifferentiated and differentiated U937 cells, which were pre-loaded with DCFH-DA. Hypoxis extracts and purified compounds had ferric reducing activities, but only rooperol had ferric reducing activities significantly greater than ascorbic acid. β-sitosterol, campesterol and cholesterol significantly increased SOD activity in Chang liver cells, while H. stellipilis, H. sobolifera and rooperol decreased SOD activity. Anticancer, anti-inflammatory and antioxidant properties of the Hypoxis extracts may be attributed to the β-sitosterol content, because Hypoxis chloroform extracts contained very little or no hypoxoside. Unidentified compounds, and synergistic and additive effects of the compounds may have contributed to the biological effects. This study confirms previous reports that rooperol is the active compound. Results provide scientific data on the medicinal properties of one of the most frequently used medicinal plants in South Africa.
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Karpf, Ditte Maria. "Intestinal lipoprotein secretion and lymphatic transport of poorly aqueous soluble compounds /." Kbh. : The Danish University of Pharmaeutical Sciences, Department of Pharmaceutics, 2005. http://www.dfuni.dk/index.php/Previous_PhD_Defences_2005/1735/0/.

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Salgado, Ricardo Manuel Nunes. "The removal of xenobiotic compounds from wastewater through the use of biological processes and advanced oxidation technologies." Doctoral thesis, Faculdade de Ciências e Tecnologia, 2011. http://hdl.handle.net/10362/6918.

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Dissertação apresentada para obtenção do Grau de Doutor em Engenharia Química e Bioquímica pela Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia
FCT/MCTES projects PTDC/AMB/65702/2006 and SFRH/PROTEC/49449/2009 and SFRH/BPD/30800/2006 ; COST Action 636
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Geller, Fabiana Cristina [Verfasser]. "Isolation, Structure Elucidation and Biological Investigation of Active Compounds in Cordia americana and Brugmansia suaveolens / Fabiana Cristina Geller." München : Verlag Dr. Hut, 2011. http://d-nb.info/1011441357/34.

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Geller, Fabiana [Verfasser]. "Isolation, Structure Elucidation and Biological Investigation of Active Compounds in Cordia americana and Brugmansia suaveolens / Fabiana Cristina Geller." München : Verlag Dr. Hut, 2011. http://nbn-resolving.de/urn:nbn:de:101:1-20110503905.

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Seotsanyana-Mokhosi, Itumeleng. "Photosensitizing properties of non-transition metal porphyrazines towards the generation of singlet oxygen." Thesis, Rhodes University, 2001. http://hdl.handle.net/10962/d1006086.

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Metallophthalocyanine complexes containing non-transition metals are very useful as sensitizers for photodynamic therapy, a cure for cancer that is based on visible light activation of tumour localized photo sensitizers. Excited sensitizers generate singlet oxygen as the main hyperactive species that destroy the tumour. Water soluble sensitizers are sought after for the convenience of delivery into the body. Thus, phthalocyanine (pc), tetrapyridinoporphyrazines (tppa) and tetramethyltetrapyridinoporphyrazines (tmtppa) with non-transition central metal atoms of Ge, Si, Sn and Zn were studied. First was the synthesis of these complexes, followed by their characterisation. The characterisation involved the use of ultraviolet and visible absorption spectroscopy, infrared spectroscopy, nuclear magnetic resonance spectroscopy, electrochemical properties and elemental analysis. Photochemical properties of the complexes were then investigated. Photolysis of these macrocycles showed two processes; -reduction of the dye and photobleaching, which leads to the disintegration of the conjugated chromophore structure of the dye. Photobleaching is the reductive quenching of the excited state of the sensitizers. The intensity of the quenching decreased progressively from tmtppa, tppa to pc metal complexes with photobleaching quantum yields, 6.6 x 10.5⁻¹, 1.8 x 10.5⁻¹ and 5.4 x 10⁻⁶ for Zntmtppa, Zntppa and Znpc, respectively. Efficiency of singlet oxygen sensitization is solvent dependent with very different values obtained for the same compound in different solvents, for example, 0.25 and 0.38 were observed as singlet oxygen quantum yields for Gepc complex in DMSO and DMF respectively. In DMSO the efficiency of ¹O₂ generation decrease considerably from pc to tppa and finally tmtppa. In water Getmtppa exhibits much higher singlet oxygen quantum yield, hence promising to be effective as a sensitizer for photodynamic therapy.
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Sbardella, Luca. "Evaluation and comparison of advanced treatment technologies to enhance the removal of pharmaceutical active compounds from wwtp secondary effluent." Doctoral thesis, Universitat de Girona, 2019. http://hdl.handle.net/10803/668690.

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The presence of several pharmaceutical active compounds (PhACs) in water bodies has garnered increasing attention and worldwide concern. The effluents from wastewater treatment plants (WWTPs) are one of the main sources of PhACs in aquatic environments. Advanced tertiary treatments are required to improve the quality of WWTP effluents discharged into sensitive receiving water bodies. This thesis has focused on biological activated carbon coupled with ultrafiltration (BAC-UF) and UV-C activated peroxydisulfate and peroxymonosulfate (UV/PDS and UV/PMS). The BAC-UF technology has been evaluated at pilot-scale during one year of operation, assessing the removal of 15 PhACs at environmentally relevant concentration. With respect to UV/PDS and UV/PMS technologies, they were preliminarily assessed with a set of lab-scale experiments and then, validated at pilot-scale simulating real operating conditions. Finally the comprehensive evaluation of these advanced treatment technologies identified some of the practical factors limiting the potential application of BAC-UF, UV/PDS and UV/PMS technologies.
La presencia de varios compuestos activos farmacéuticos (PhACs) en las masas de agua ha ganado una atención creciente y preocupación mundial. Los efluentes de las depuradores son una de las principales fuentes de PhAC en entornos acuáticos. Se requieren tratamientos terciarios avanzados para mejorar la calidad de los efluentes de las depuradoras que abocan en masas de agua receptoras sensibles. Esta tesis se focaliza en la tecnologias de carbón activo biológico combinado con la ultrafiltración (BAC-UF) y el peroxidisulfato y el peroximonosulfato activados por UV-C (UV/PDS y UV/PMS). La tecnología BAC-UF se ha evaluado a escala piloto durante un año de operacion, evaluando la eliminación de 15 PhACs. Con respecto a UV/PDS y UV/PMS, se evaluaron preliminarmente a escala de laboratorio y luego se validaron a escala piloto, simulando condiciones reales de operación. Finalmente, la evaluación integral de estas tecnologías de tratamiento avanzadas identificó algunos de los factores prácticos que limitan la aplicación potencial de las tecnologías BAC-UF, UV/PDS y UV/PMS.
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Mohammed, Warda. "Optimizing Sample Dissolution Methods of Low Water Soluble Intermediate Organic Compounds to Support Environmental Risk Assessment during Active Pharmaceutical Ingredient Manufacturing." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-93416.

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This project focus on investigating the dissolution of low water-soluble intermediate organic compounds called active pharmaceutical ingredients (API) and organic substances that are manufactured by a pharmaceutical company, Cambrex Karlskoga in Sweden. Several dissolution methods were used and evaluated using methods including total organic carbon (TOC), chemical oxygen demand (COD), biochemical oxygen demand (BOD) and Microtox toxicity test. The selection of solvents were based on previous studies and specifications from the Swedish Institute of Standards, SIS.The performance of eight solvents for different organic substances were evaluated using the above mentioned methods. Solvents that are highly volatile and have low solubility in water were excluded. Therefore, dimethyl sulfoxide (DMSO), dimethylformamide (DMF) and Pluronic F-68, that had highest water solubility, low acute toxicity and not degradable by microorganisms, were further used to dissolve four organic substances. Furthermore, DMSO and DMF were then also used to dissolve four censored chemicals with addition of physical treatment and solvent mixtures (DMF:DMSO with ratio 1:2).Results from each method were discussed and statistical tests were also performed in order to compare different dissolution methods. In addition, quality control and quality assurance were made in order to ensure the quality of measured values from analytical methods. Four organic substances were dissolve in DMSO, DMF and Pluronic F-68 with dissolution ≥79% using six ratios of DMSO and DMF and five ratios of Pluronic F-68 which were analyzed using TOC. Physical treatment increased dissolution of two APIs with 40%. Using BOD, para-aminobenzonic acid (PABA) and 5-nitroisophthalic acid (5-NIPA) had values higher than the guideline values, which indicate high biodegradability of these organic substances. PABA, 5-NIPA and bupivacaine base were acute toxic where PABA showed EC50 values of 27.9 mg/L using DMSO and 36.0 mg/L using DMF, and EC50 values of 5-NIPA were 102 mg/L using DMSO and 84.0 mg/L using DMF, and bupivacaine base had EC50 value of 174 mg/L using solvent mixture (DMF:DMSO with ratio 1:2). With increasing amount of Pluronic F-68, 5-NIPA had increased values of EC50, thereby Pluronic F-68 was not appropriate to use.In conclusion, DMSO and DMF were most appropriate solvents to use in order to dissolve APIs and organic substances with analyte: DMSO ratio of 1:0.5 and analyte: DMF ratio of 1:0.25. In addition, physical treatment could be used in order to increase dissolution of the APIs.
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Books on the topic "Biological active compounds"

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Natural products and their active compounds on disease prevention. Hauppauge, N.Y: Nova Science Publishers, 2011.

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Sukhareva, N. N. Biologically active substances of protozoa. Dordecht: Kluwer Academic, 2002.

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Kusuma, Irawan W. Exploration of biological activities and isolation of the active compounds from ethnobotanically-selected medicinal plants: Final report international collaborative research and publication. Samarinda]: Mulawarman University, 2010.

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Yue, Wu. Biologically-active compounds in seaweed extracts. Portsmouth: University of Portsmouth, School of Pharmacy and Biomedical Science, 1996.

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Whapham, C. A. Biologically active compounds in seaweed extracts. Portsmouth: University of Portsmouth, School of Pharmacy & Biomedical Sciences, 1995.

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Mao, Justin Y. Synthetic approaches to syn-diol containing biologically active compounds. St. Catharines, Ont: Brock University, Dept. of Chemistry, 2002.

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Gašić, Olga. Biologically active compounds of plants in the Fruška Gora mountain. Novi Sad: Matica srpska, Odeljenje za prirodne nauke, 1997.

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Seelig, Bruce Duane. Water resource impacts: From medicines and other biologically active substances. Fargo, N.D: NDSU Extension service, 2005.

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(41st), IUPAC Congress. Advanced biologically active polyfunctional compounds and composites: Health, cultural heritage and environmental protection. Edited by Lekishvili N, Zaikov, G. E. (Gennadiĭ Efremovich), 1935-, and Howell, B. A. (Bobby Avery), 1942-. New York: Nova Science, 2010.

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Supratman, Unang. Biologically active compounds from Indonesian aglaia plants: Overseas research collaboration and international publications : final report. Jatinangor]: Ministry of Education and Culture, Universitas Padjadjaran, Faculty of Mathematics and Natural Sciences, 2012.

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Book chapters on the topic "Biological active compounds"

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Akhtar, Nosheen, Sunbal Khalil Chaudhari, Sohaib Arshad, Hira Fatima, Muhammad Shoaib Amjad, and Saboon. "Biological Activities and Nutritional Value of Physalis peruviana L." In Natural Bio-active Compounds, 587–98. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7154-7_21.

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Wichtl, M. "Curcuma(Tumeric): Biological Activity and Active Compounds." In ACS Symposium Series, 133–39. Washington, DC: American Chemical Society, 1998. http://dx.doi.org/10.1021/bk-1998-0691.ch011.

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Caprioli, Richard M. "Coupling Chromatographic Techniques with FABMS for the Structural Analysis of Biological Compounds." In Biologically Active Molecules, 79–96. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74582-9_6.

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do Amaral, Wanderlei, Cícero Deschamps, Humberto R. Bizzo, Marco Antonio S. Pinto, Luiz Everson da Silva, Luiz A. Biasi, Thiago S. Freitas, et al. "Essential Oil of Baccharis milleflora in the Atlantic Rain Forest of the Paraná State in Brazil: Chemical Composition and Biological Evaluation." In Natural Bio-active Compounds, 599–608. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7154-7_22.

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Franzetti, Andrea, Elena Tamburini, and Ibrahim M. Banat. "Applications of Biological Surface Active Compounds in Remediation Technologies." In Advances in Experimental Medicine and Biology, 121–34. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-5979-9_9.

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Tylkowski, Bartosz, and Irene Tsibranska. "9. Polymer application for separation/filtration of biological active compounds." In Polymer Engineering, edited by Bartosz Tylkowski, Karolina Wieszczycka, and Renata Jastrzab, 277–92. Berlin, Boston: De Gruyter, 2017. http://dx.doi.org/10.1515/9783110469745-009.

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Benigni, R., C. Andreoli, M. Cotta-Ramusino, and A. Giuliani. "Biological systems for measuring mutagenicity and carcinogenicity, and ‘average’ properties of active compounds." In Trends in QSAR and Molecular Modelling 92, 301–2. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1472-1_54.

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Hiyama, Tamejiro, and Hisashi Yamamoto. "Biologically Active Organofluorine Compounds." In Organofluorine Compounds, 137–82. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-662-04164-2_5.

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Breydo, Leonid. "Boron, Biologically Active Compounds." In Encyclopedia of Metalloproteins, 295–99. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-1533-6_483.

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Breydo, Leonid. "Arsenic, Biologically Active Compounds." In Encyclopedia of Metalloproteins, 143–49. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-1533-6_484.

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Conference papers on the topic "Biological active compounds"

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Gobbi, Alberto, D. Poppinger, and B. Rohde. "Finding Biological Active Compounds in Large Databases;." In The 1st International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 1997. http://dx.doi.org/10.3390/ecsoc-1-02069.

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Agafonova, N. A., E. V. Shchegolkov, Ya V. Burgart, V. I. Saloutin, and M. V. Ulitko. "Synthesis of biological active compounds based on trifluoromethylcontaining 4-nitrosopyrazoles." In VIII Information school of a young scientist. Central Scientific Library of the Urals Branch of the Russian Academy of Sciences, 2020. http://dx.doi.org/10.32460/ishmu-2020-8-0009.

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e-pot nitrosation of 1,3-diketones or their lithium salts followed by treatment of hydrazines. Reduction of the nitroso-derivatives made it possible to obtain the 4-amino-3-trifluoromethylpyrazoles chlorides. Cytotoxic activity of the compounds wase evaluated in vitro
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Galvis, Carlos E. Puerto, and Vladimir V. Kouznetsov. "An Efficient Three-step Synthesis of -Phenethylcinnamamides Toward New Biological Active Compounds." In 14th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0379-1.

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BIKOVENS, Oskars, Jevgenija PONOMARENKO, Sarmite JANCEVA, Maris LAUBERTS, Laima VEVERE, and Galina TELYSHEVA. "DEVELOPMENT OF THE APPROACHES FOR COMPLEX UTILIZATION OF BROWN ALGAE (FUCUS VESICULOSUS) BIOMASS FOR THE OBTAINING OF VALUE-ADDED PRODUCTS." In RURAL DEVELOPMENT. Aleksandras Stulginskis University, 2018. http://dx.doi.org/10.15544/rd.2017.091.

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The seaweed collected after stranding on beaches of Latvia is underexploited natural resource, which has a potential as raw material for biologically active compound extraction for cosmetic and pharmacy and fertilizer in sustainable agriculture. The aim of the present study was development of the approach for the processing of brown alga Fucus vesiculosus biomass, collected from the Gulf of Riga. The thorough characterization of the chemical composition of Fucus vesiculosus has shown that it is a potential source for obtaining of nitrogen-containing fertilizers, and biologically active compounds. One of the proposed approaches for the processing of the Fucus vesiculosus biomass under study includes algae extraction with organic solvents and CaCl2 solution and obtaining soil organic amendment on the basis of the extract-free residue. The ethyl acetate extract was rich in phenolic compounds (430 ± 30 GAE mg/g) with high antioxidant activity in DPPH• and ABTS•+ tests. The ethanol extract contained significant amounts of phlorotannins that was confirmed by the data of LC-MS/MS analysis. The CaCl2 extract was used for the obtaining of sulphated polysaccharide fucoidane (yield ≈7% on the basis of oven dry matter, o.d.m.), which has numerous biological activities. The extract-free residue didn’t show phytotoxicity. The extract free algal biomass exhibited positive effect in root elongation tests with oat (Avena sativa). As alternative approach for processing of the algal biomass, the mechano-chemical treatment of algal biomass with lignin was proposed. EPR analyses confirmed interaction between algal biomass and lignin.
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Zangiligi, Mariam Al, Ramadan Mussa, E. Yu Aleksandrova, and S. N. Suslina. "RATIONALE FOR THE USE OF SESBANIA SESBAN (L.) AS A PROMISING SOURCE OF BIOLOGICAL ACTIVE COMPOUNDS." In 90 лет - от растения до лекарственного препарата: достижения и перспективы. Москва: Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт лекарственных и ароматических растений", 2021. http://dx.doi.org/10.52101/9785870191003_2021_354.

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Markova, Yu A., L. A. Belovezhets, M. S. Tretyakova, A. M. Cheremnykh, and A. A. Levchuk. "The nature of the carbon source as a modulator of the response of bacteria to biologically active compounds (for example, colchicine and protatranes)." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.163.

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When assessing the impact of biological active compounds (colchicine and protatranes) on Rhodococcus erythropolis against the background of various carbon sources, an unusual effect of low concentrations of colchicine was revealed, that expressed in sharp stimulation of bacterial metabolism.
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Fan, Xing Xing, Maria Pik Wong, Zhi Wei Cao, Jian Lin Wu, Hua Zhou, Zhi Hong Jiang, Liang Liu, and Elaine Lai-Han Leung. "Abstract 2255: Distinct biological effect of inhibiting the metabolic pathway using active compounds derived from Chinese medicinal herbs in non-small cell lung cancer cells with differentEGFRmutational profiles." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2255.

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Zedan, Randa Hisham, Zahoor Ul-Hassan, Roda Al-Thani, Quirico Migheli, and Samir Jaoua. "Biological Control of Mycotoxigenic Fungi and Ochratoxin by the In-Vitro Application of a Qatari Burkholderia cepacia Strain (QBC03)." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0091.

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Mycotoxins are secondary metabolites synthesized by mycotoxigenic fungi belonging mainly to three major fungal genera that are Aspergillus, Fusarium and Penicillium. The latter mycotoxigenic fungi contaminate plants and different food commodities and cause various health concerns (carcinogenicity, mutagenicity, nephrotoxicity, etc...) due to their corresponding mycotoxins. One of the most studied mycotoxins is ochratoxin A (OTA) owing to its toxicity level (classified in 2B group as possible human carcinogenic). To remediate the mycotoxins’ contamination, physical and chemical techniques can be proposed. However, the safest among all is the biological control approach. In this research, we have used the Qatari strain Burkholderia cepacia (QBC03) as a biological agent against mycotoxigenic fungi and the strain has possessed a wide antifungal spectrum against 21 species from different genera. Additionally, the antifungal activity of QBC03’s supernatant was explored on the fungal biomass and OTA synthesis of A. carbonarius in liquid media, and interestingly; both the biomass and OTA’s concentrations were massively reduced upon treatment. The effect of QBC03’s supernatant on the fungal spores’ germination was examined as well, and it was shown that the conidial germination was completely inhibited. Moreover, the supernatant of QBC03 has induced morphological alteration in the mycelia of the fungal strain. The thermal stability of the antifungal compounds in QBC03’s culture supernatant was investigated, and it was shown that metabolites of QBC03 were distinctively thermostable and they were still active even when heated at 100C. The findings of this research prove that Burkholderia cepacia strain QBC03 is an excellent candidate for the biological control of mycotoxigenic fungi and their mycotoxins particularly in local regions.
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Ryszard, Parosa, Andrzej Brożyński, Piotr Grześkowiak, Krzysztof Kowalczyk, Marek Natoński, Piotr Ziętek, and Janusz Żytkiewicz. "MICROWAVE TREATMENT OF MATERIALS IN LOW PRESSURE." In Ampere 2019. Valencia: Universitat Politècnica de València, 2019. http://dx.doi.org/10.4995/ampere2019.2019.9625.

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Ryszard Parosa, Andrzej Brożyński, Piotr Grześkowiak, Krzysztof Kowalczyk, Marek Natoński, Piotr Ziętek and Janusz Żytkiewicz PROMIS-TECH Poland Keywords: microwave treatment, low pressure heating, microwave drying Uniquely favourable characteristics of biological product can be obtained through the use of the microwave method in vacuum heating process. Microwave-vacuum drying is superior to other methods in terms of dried products' structure, flavour, colour and biological active compounds contents. But applications of such a methods seems to be much wider: drying of fruits and vegetables for consumption, drying of herbs for extraction of valuable biological compounds, for modification of seed structure (sunflowers seeds, pumpkin seeds), for pasteurisation etc. A universal system was designed for testing such processes in laboratory scale and several industrial scale system have been developed. Process of thermal treatment can be carried out with plastic drum installed inside of multi-mode microwave cavity and cavity which is connected by microwave line with reflectometer and circulator - to microwave generator. In laboratory unit generator 2.45 GHz with controlled power (from 50W to 800W) was applied. System was equipped with vacuum pump with pressure control and is controlled by computer. Most important technical parameters, like: microwave power, time of treatment, pressure inside of drum, temperature of steam – are controlled and recorded. Laboratory scale unit is shown below. Basing on laboratory scale test several technologies in industrial scale was developed. Industrial scale unit equipped with 8 generators of 3 kW (2.45 GHz) was constructed and for last 8 years has been successfully used for “production” of crispy chips which are now popular in Polish marked. Exemplary industrial scale installation is shown in photo below. Multi – drum microwave drier. Two cavity microwave industrial drier Another system for modification od seed is now constructed – ordered by big industrial producer of batons and sweet snacks. Process will be carried our inside of dielectric drum in low pressure and reactor will be equipped with 8 generators of 3 kW (2.45 GHz). Treatment time will be reduced to 3-4 minutes and next material (seeds) will be cooled down. Last project which now realized is connected with drying of wood flour applied in composite material production. System will work continuously with two airlocks and with dielectric drum and will be connected with 4 microwave generators (3 kW, 2.45 GHz). In next step planed installation will be equipped with microwave high power generator ca. 60 kW with frequency 915 MHz.
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Martins, Lucimara J., Wanessa F. Altei, Cristiane S. Schwalm, Adriano D. Andricopulo, and Fernando Coelho. "Synthesis of new biologically actived azaspiro compounds." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013917144424.

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