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Journal articles on the topic 'Biological products – Analysis'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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Giulivi, C., N. J. Traaseth, and K. J. A. Davies. "Tyrosine oxidation products: analysis and biological relevance." Amino Acids 25, no. 3-4 (2003): 227–32. http://dx.doi.org/10.1007/s00726-003-0013-0.

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Diczfalusy, Ulf. "Analysis of Cholesterol Oxidation Products in Biological Samples." Journal of AOAC INTERNATIONAL 87, no. 2 (2004): 467–73. http://dx.doi.org/10.1093/jaoac/87.2.467.

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Abstract Cholesterol oxidation products, or oxysterols, have gained increased attention since it was suggested that they participate in cell signaling as ligands for the nuclear receptors liver X receptor α and β. In addition, oxysterols serve as important intermediates in bile acid biosynthesis and are also involved in cholesterol transport. Several studies have suggested that certain oxysterols may be used as markers for oxidative stress, and still other oxysterols may be of use in diagnosing neurological diseases. This broad spectrum of functions in health and disease has created a demand for accurate and reliable methods to measure oxysterols in complex biological matrixes. At present, the most reliable and sensitive method for oxysterol determination in biological materials is isotope-dilution gas chromatography-mass spectrometry using deuterium-labeled internal standards. With this technique, the major oxysterols in human blood plasma and atherosclerotic plaques have been carefully determined. The knowledge of oxysterol contents in other tissues and organs is still very scarce. As oxysterols are found to participate in an increasing number of cellular events, it is obvious that improved methods are needed for their analysis to understand their roles in the living cell.

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HORAN, IAN, and PAUL T. TOMKINS. "The Biological and Chemical Analysis of Complex Natural Products." Biochemical Society Transactions 28, no. 1 (2000): A46. http://dx.doi.org/10.1042/bst028a046b.

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Meldal, Morten, and Phaedria M. St Hilaire. "Synthetic methods of glycopeptide assembly, and biological analysis of glycopeptide products." Current Opinion in Chemical Biology 1, no. 4 (1997): 552–63. http://dx.doi.org/10.1016/s1367-5931(97)80052-x.

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Logue, Brian A., Diane M. Hinkens, Steven I. Baskin, and Gary A. Rockwood. "The Analysis of Cyanide and its Breakdown Products in Biological Samples." Critical Reviews in Analytical Chemistry 40, no. 2 (2010): 122–47. http://dx.doi.org/10.1080/10408340903535315.

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Pilkington. "A Chemometric Analysis of Deep-Sea Natural Products." Molecules 24, no. 21 (2019): 3942. http://dx.doi.org/10.3390/molecules24213942.

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Deep-sea natural products have been created by unique marine organisms that thrive in a challenging environment of extreme conditions for its inhabitants. In this study, 179 deep-sea natural products isolated from 2009 to 2013 were investigated by analysing their physicochemical properties that are important indicators of the ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) profile of a compound. The study and analysis of these molecular descriptors and characteristics enabled the defining of these compounds in various chemical spaces, particularly as an indication of their drug-likeness and position in chemical space and is the first to be conducted to analyse deep-sea derived natural products. It was found that ~40% of all deep-sea natural products were drug-like and 2/3 were within Known Drug Space (KDS), highlighting the high drug-likeness of a significant proportion of deep-sea natural products, most of which have already been shown to have notable biological activities, that should be further investigated as potential therapeutics. Furthermore, this study was able to reveal the general structural differences between compounds from Animalia, Bacteria and Fungi organisms where it was observed that natural products from members of the Animalia kingdom are structurally more varied than compounds from bacteria and fungi. It was also noted that, in general, fungi-derived compounds occupy a more favourable position in drug-like chemical space and are a rich and promising source of biologically-active natural products for the purposes of drug development and therapeutic application.

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de Witte, Bavo, Herman van Langenhove, Kristof Demeestere, and Jo Dewulf. "Advanced Oxidation of Pharmaceuticals: Chemical Analysis and Biological Assessment of Degradation Products." Critical Reviews in Environmental Science and Technology 41, no. 3 (2011): 215–42. http://dx.doi.org/10.1080/10643380902728698.

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DORAN, MICHAEL, and DENIS J. REEN. "Analysis of complement activation products in biological fluids using polyacrylamide gel electrophoresis." Biochemical Society Transactions 16, no. 2 (1988): 160–61. http://dx.doi.org/10.1042/bst0160160.

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Anna, Gałązka, Gawryjołek Karolina, and Kocoń Anna. "The effect of the same microbial products on basic biological activities of soil under cereal crops." Plant, Soil and Environment 63, No. 3 (2017): 111–16. http://dx.doi.org/10.17221/690/2016-pse.

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The aim of this research was a preliminary evaluation of the effectiveness of using three preparations which improve soil fertility and yield of plants. Field tests with microbial products: EM (effective microorganisms), EmFarma Plus and UGmax were carried out in the Agricultural Research Centre in Grabowo, Poland. The experimental plants were: spring triticale, spring barley and winter wheat. Bioproducts were applied directly into stubble or straw left in the field after harvesting grain and straw with an addition of nitrogen and were compared against control treatments, without the use of the above preparations. The implied treatments are determined for soil biological activity and the basic chemical properties of the soil. The microbiological tests showed a statistically significant difference between the control treatments and treatments with EM and UGmax preparations (a statistically significant increase in microbial biomass and activity of dehydrogenases). Analysis of principal component analysis (PCA) explained 52.54% of the variation and separated the three groups: I (UGmax), II (EM) and III (control and EmFarma Plus). It was found that the average yield of triticale grains was approximately only by 4% higher in treatments where EM and EmFarma Plus were applied, while in treatments with UGmax, triticale yielded at control level.

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Fanali, Chiara, Giovanni D’Orazio, Alessandra Gentili, and Salvatore Fanali. "Analysis of Enantiomers in Products of Food Interest." Molecules 24, no. 6 (2019): 1119. http://dx.doi.org/10.3390/molecules24061119.

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The separation of enantiomers has been started in the past and continues to be a topic of great interest in various fields of research, mainly because these compounds could be involved in biological processes such as, for example, those related to human health. Great attention has been devoted to studies for the analysis of enantiomers present in food products in order to assess authenticity and safety. The separation of these compounds can be carried out utilizing analytical techniques such as gas chromatography, high-performance liquid chromatography, supercritical fluid chromatography, and other methods. The separation is performed mainly employing chromatographic columns containing particles modified with chiral selectors (CS). Among the CS used, modified polysaccharides, glycopeptide antibiotics, and cyclodextrins are currently applied.

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Sukhanova, S. M., and N. E. Zakharova. "Culture Media in Pharmacopoeial Analysis: Use, Current Requirements, Standardisation." BIOpreparations. Prevention, Diagnosis, Treatment 19, no. 3 (2019): 136–44. http://dx.doi.org/10.30895/2221-996x-2019-19-3-136-144.

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Culture media with predetermined specific characteristics play a key role in ensuring safety, quality and efficacy of medicinal products, especially biologicals. It is necessary to formulate clear criteria for culture media suitability, because they are used not only in manufacture, but also in quality control of medicinal products. The expansion of the range of complex high-technology medicinal products containing biologically derived substances as active ingredients, whose quality and properties are tested by biological methods, calls for more stringent requirements for the quality of culture media. The aim of the study was to analyse requirements for the culture media used in the production of medicinal products — in order to identify approaches to the development of a national standard. Currently, culture media are not included into the State Register of Medicinal Products, and there are no standards that could be used by manufacturers to confirm that a culture medium complies with specific safety, efficacy and quality requirements. The paper summarises the results of the analysis of the State Pharmacopoeia of the Russian Federation, 14th ed., and nine leading world pharmacopeias’ requirements for culture media used for various purposes (manufacture, auxiliary purposes, and quality control). Most countries have adopted requirements mainly for those culture media that are used in purity tests. The analysis revealed differences both in the lists of requirements (test strains, incubation and storage conditions, preparation for use, suitability assessment), and the approaches to the establishment and presentation of requirements. The paper discusses the main challenges and risks associated with the quality control of culture media in accordance with the requirements of the State Pharmacopoeia of the Russian Federation, 14th ed. It outlines current national and international ways of improving the quality of culture media used in the production of medicinal products, and substantiates the need to develop an appropriate national standard. The paper suggests approaches to the development and standardisation of requirements for the quality of various types of media used in the production and control of medicines. These approaches could be used in the preparation of the general chapter Culture media.

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Ulyanich, О. I., S. A. Vdovenko, V. V. Yatsenko, and M. M. Chmil. "Growth, development and yield of beet varieties under the action of biological products." Collected Works of Uman National University of Horticulture 1, no. 98 (2021): 92–104. http://dx.doi.org/10.31395/2415-8240-2021-98-1-92-104.

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The search for new conditions for growing vegetables in organic crops in order to obtain safe products and in connection with changes in climatic conditions requires an immediate solution. The article considers and proves that the use of biological products affects the formation of highly productive crops and promotes the production of products with a high content of biologically active substances. Studies have shown a positive effect of biological products on the growth and development and yield of beetroot varieties Delicatessen and Red Ball. Studies have been conducted to study the technological aspects of growing vegetables, in particular with the use of biological products, taking into account the environmental impact of both growth processes and quantitative and qualitative indicators. Features of various biological products and their efficiency are analyzed. A comparative analysis of the use of biologicals, which allowed to comprehensively assess the impact of elements of cultivation technology on phenological, biometric, indicators, yield and quality of table beet products, development and improvement of elements of technology for their cultivation in the forest-steppe of Ukraine. This involves the use of highly productive varieties, the use of various effective biological products, is relevant for the spread and cultivation of table beets in the forest-steppe of Ukraine. Phenological observations of canteen beet plants showed that they developed differently and reacted differently in the phases of growth and development, depending on the introduced biological products. The technical ripeness phase began on days 121–129 and was longer than in the control. With the introduction of Solutin and Chlorella – 128–129 days, and in short - with the introduction of biological products Helprost vegetable, Helprost vegetable + Phytohelp, Solutin + Phytohelp – 121–125 days. It was proved that table beet plants differed in height, number of leaves, leaf blade area and their total area per hectare, which compared to the control were from the use of a tank mixture of biological products Helprost vegetable + Phytohelp – 28.3–28.7 thousand m2/ha, which is significantly higher than the control by 13.6–14.8 thousand m2/ha. The area of leaves was slightly lower as a result of the use of other drugs and mixtures – 21.8–22.6 thousand m2/ha. The use of a mixture of drugs Helprost vegetable + Phytohelp contributed to an increase in the mass of the root of table beets by 255–350 g, which is significantly higher than the control by 9–10 g. A positive effect on the yield of beetroot was shown by the vegetable Helprost preparation, as well as a mixture of vegetable Helprost + Phytohelp preparations, the use of which provided a yield of 52.4–63.8 t/ha. The use of a mixture of biological products Solutin + Phytohelp improves the appearance of the plant, increases resistance to harmful microorganisms, and the marketable yield increases to 26.0 t/ha and significantly exceeds the control by 3.2 t/ha.

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Smith, Pamela J. "Patent Rights and Trade: Analysis of Biological Products, Medicinals and Botanicals, and Pharmaceuticals." American Journal of Agricultural Economics 84, no. 2 (2002): 495–512. http://dx.doi.org/10.1111/1467-8276.00313.

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MELDAL, M., and P. M. S. HILAIRE. "ChemInform Abstract: Synthetic Methods of Glycopeptide Assembly and Biological Analysis of Glycopeptide Products." ChemInform 29, no. 26 (2010): no. http://dx.doi.org/10.1002/chin.199826350.

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Pachla, Lawrence A., Donald L. Reynolds, and Peter T. Kissinger. "Analytical Methods for Determining Ascorbic Acid in Biological Samples, Food Products, and Pharmaceuticals." Journal of AOAC INTERNATIONAL 68, no. 1 (1985): 1–12. http://dx.doi.org/10.1093/jaoac/68.1.1.

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Abstract Over the last decade, numerous publications have appeared describing \ analyses for ascorbic acid in food products, pharmaceuticals, and biological samples. This review focuses on the chemistry associated with many of these procedures. The papers discussed have historical importance, are important to understanding the method, or have significantly advanced ascorbic acid analysis. The review has 4 major, sections: spectroscopic, electrochemical, enzymatic, and chromatographic methods of analysis.

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Ilinskiy, Andrey. "ANALYSIS OF BIOLOGICAL ABSORPTION COEFFICIENTS OF HEAVY METALS FOR FODDER BEET." EurasianUnionScientists 6, no. 2(71) (2020): 9–12. http://dx.doi.org/10.31618/esu.2413-9335.2020.6.71.612.

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The results of a field lysimetric experiment on podzolized сhernozem to study the coefficients of biological absorption of heavy metals and trace elements for root crops and tops of fodder beets using various systems of mineral fertilizers are presented. Analysis of the empirical series of accumulation of elements in the main and byproducts of fodder beet plants showed that the level of accumulation of zinc, lead and cadmium in root crops is significantly lower than in the tops, and the copper content is relatively evenly distributed between the main and by-products according to the variants of the experiment. In the variant with an increased agrochemical background, there was a decrease in the content of copper, zinc and lead in the main and by-products of feed beets, which may be due to the effect of biological dilution when using mineral fertilizers.

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Nývlt, Michal, and Jiří Pazderka. "ANALYSIS OF CORROSION PRODUCTS FROM WW2 CONCRETE BUNKERS IN CZECHIA." Acta Polytechnica CTU Proceedings 22 (July 25, 2019): 77–82. http://dx.doi.org/10.14311/app.2019.22.0077.

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The paper deals with analysis of corrosion products from historic concrete bunkers which were built in the 1930’s. Most of these objects evince numerous failures due to water penetration into the concrete structures. Two heavy bunkers became the target of research which was focused on chemical and biological analysis of corrosion products from concrete structures. The results showed that concrete used for two analyzed fortifications successfully resisted the long-lasting effects of chemical corrosion as well as bio-corrosion (this corrosion causes only aesthetic defects).

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Popova, Nadezhda, Yuliya Pisklyukova, and Viktoriya Orlova. "The use of bio-efficient plant materials to optimize the fatty acid composition of poultry terrins." BIO Web of Conferences 30 (2021): 01014. http://dx.doi.org/10.1051/bioconf/20213001014.

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The development of functional products characterized by high biological efficiency is an urgent task. The article presents the results of the development of balanced-fatty acid terrins from poultry meat. To increase the biological effectiveness of chopped products, raw materials containing omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) were selected. Based on the analysis of the chemical composition of the raw material kit, the intervals for the Introduction of ingredients containing biologically effective components are calculated. Their optimum amount has been experimentally established. The resulting innovative products are characterized by a balanced composition in terms of content and ratio of omega-3 and omega-6 PUFAs. In addition, the value of the indicator of biological value has increased. Developed poultry terrins can be recommended both for a wide range of consumers, and for use in diet (including low-carb diets), baby food. The developed terrines will expand the range of chopped poultry products of functional orientation.

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Dah-Nouvlessounon, Durand, Hubert Adoukonou-Sagbadja, Nafan Diarrassouba, et al. "Phytochemical Analysis and Biological Activities ofCola nitidaBark." Biochemistry Research International 2015 (2015): 1–12. http://dx.doi.org/10.1155/2015/493879.

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Kola nut is chewed in many West African cultures and is used ceremonially. The aim of this study is to investigate some biological effects ofCola nitida’s bark after phytochemical screening. The bark was collected, dried, and then powdered for the phytochemical screening and extractions. Ethanol and ethyl acetate extracts ofC. nitidawere used in this study. The antibacterial activity was tested on ten reference strains and 28 meat isolatedStaphylococcusstrains by disc diffusion method. The antifungal activity of three fungal strains was determined on the Potato-Dextrose Agar medium mixed with the appropriate extract. The antioxidant activity was determined by DPPH and ABTS methods. Our data revealed the presence of various potent phytochemicals. For the reference and meat isolated strains, the inhibitory diameter zone was from17.5±0.7 mm (C. albicans) to9.5±0.7 mm (P. vulgaris). The MIC ranged from 0.312 mg/mL to 5.000 mg/mL and the MBC from 0.625 mg/mL to >20 mg/mL. The highest antifungal activity was observed withF. verticillioidesand the lowest one withP. citrinum. The two extracts have an excellent reducing free radical activity. The killing effect ofA. salinalarvae was perceptible at 1.04 mg/mL. The purified extracts ofCola nitida’s bark can be used to hold meat products and also like phytomedicine.

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Rodionova, K. O., and A. P. Paliy. "Analysis of contemporary meat and meat products’ processing methods." Journal for Veterinary Medicine, Biotechnology and Biosafety 5, no. 2 (2019): 31–38. http://dx.doi.org/10.36016/jvmbbs-2019-5-2-6.

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For today, the issue of maximum preservation of meat and meat products at all stages of their production, storage, transportation and realization does not lose its relevance. Existing ways of food products’ preservation for prevention of their microbiological damage are divided into three groups: physical, chemical and biological. The article gives an analysis of modern methods of meat and meat products’ processing. Physical (chill, freezing, super freezing, ionizing irradiation, ultraviolet irradiation, pressure processing, laser irradiation) and chemical (with the use of organic acids, trisodium phosphate, extracts of plants with bacteriostatic properties etc.) methods of meat and meat products’ preservation are characterized. The data on the methods for extension of realization term due to the use of modern packaging materials (modified atmosphere, system of ‘active packaging’ and aseptic packaging) is given. The advantages and disadvantages of each of these methods are indicated.

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Vogtmann, H. "From Healthy Soil to Healthy Food: An Analysis of the Quality of Food Produced under Contrasting Agricultural Systems." Nutrition and Health 6, no. 1 (1988): 21–35. http://dx.doi.org/10.1177/026010608800600103.

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Studies under controlled experimental conditions show a clear advantage for staple food grown under biological/ecological farming conditions as compared to those from conventional farming methods. This is especially true for the vegetative parts of plant products, where lower undesirable (e.g. nitrates) and higher desirable (e.g. vit.C, trace elements) components are present. A better storage quality of plant products (e.g. cabbage, carrots) is also frequently the consequence of biological/ecological farming practices. An overall significantly lower level of residues of agrochemicals has been demonstrated in such products. It is increasingly noticeable, that especially in Central Western Europe, consumers are not exclusively interested in “healthier” food for themselves but also in an healthy environment. This is one of the important reasons, why they are interested in buying food from biological/ecological farming systems and why they are prepared to pay higher prices for such products.

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Ngwenya, N., and E. M. N. Chirwa. "Biological removal of cationic fission products from nuclear wastewater." Water Science and Technology 63, no. 1 (2011): 124–28. http://dx.doi.org/10.2166/wst.2011.021.

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Nuclear energy is becoming a preferred energy source amidst rising concerns over the impacts of fossil fuel based energy on global warming and climate change. However, the radioactive waste generated during nuclear power generation contains harmful long-lived fission products such as strontium (Sr). In this study, cationic strontium uptake from solution by microbial cultures obtained from mine wastewater is evaluated. A high strontium removal capacity (qmax) with maximum loading of 444 mg/g biomass was achieved by a mixed sulphate reducing bacteria (SRB) culture. Sr removal in SRB was facilitated by cell surface based electrostatic interactions with the formation of weak ionic bonds, as 68% of the adsorbed Sr2+ was easily desorbed from the biomass in an ion exchange reaction with MgCl2. To a lesser extent, precipitation reactions were also found to account for the removal of Sr from aqueous solution as about 3% of the sorbed Sr was precipitated due to the presence of chemical ligands while the remainder occurred as an immobile fraction. Further analysis of the Sr-loaded SRB biomass by scanning electron microscopy (SEM) coupled to energy dispersive X-ray (EDX) confirmed extracellular Sr2+ precipitation as a result of chemical interaction. In summary, the obtained results demonstrate the prospects of using biological technologies for the remediation of industrial wastewaters contaminated by fission products.

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Komlosh, Weinstein, Loupe, et al. "Physicochemical and Biological Examination of Two Glatiramer Acetate Products." Biomedicines 7, no. 3 (2019): 49. http://dx.doi.org/10.3390/biomedicines7030049.

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Herein we compared 40 mg/mL lots of the active ingredient, glatiramer acetate, manufactured by Mylan/Natco to the active ingredient, glatiramer acetate in Copaxone (Teva Pharmaceuticals, Ltd., Netanya Israel) using physicochemical (PCC) methods and biological assays. No differences were seen between the Mylan/Natco and Teva lots with some low resolution release PCC assays (amino acid analysis, molecular weight distribution, interaction with Coomassie Brilliant Blue G-250). Changes in polydispersity between Mylan/Natco and Copaxone lots were found using size exclusion chromatography and the high resolution PCC method, known as Viscotek, and suggestive of a disparity in the homogeneity of mixture, with a shift towards high molecular weight polypeptides. Using RPLC-2D MALLS, 5 out of 8 Mylan/Natco lots fell outside the Copaxone range, containing a high molecular weight and high hydrophobicity subpopulation of polypeptides not found in Copaxone lots. Cation exchange chromatography showed differences in the surface charge distribution between the Copaxone and Mylan/Natco lots. The Mylan/Natco lots were found to be within Copaxone specifications for the EAE model, monoclonal and polyclonal binding assays and the in vitro cytotoxicity assay, however higher IL-2 secretion was shown for three Mylan/Natco lots in a potency assay. These observations provide data to inform the ongoing scientific discussion about the comparability of glatiramer acetate in Copaxone and follow-on products.

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Hron, J., and T. Macák. "Control of food products’ quality." Agricultural Economics (Zemědělská ekonomika) 55, No. 5 (2009): 221–28. http://dx.doi.org/10.17221/28/2009-agricecon.

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The paper deals with one of the significant parts of the concept related to controlling production quality, which is the analysis of production quality stability done for the following production procedure regulation aimed at the food manufacturing industry. The proposed methodology (respecting the change of location and variability of the food quality characteristics) will be introduced on the milk quality regulation. Also, there is the frequent problem solved out here in the report that relates to food quality measuring – their self-regulation by using the statistical calculation of self-regulation higher classes’ coefficients and also using the functional statement taken from the differential description.

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Vološin, J., L. Smutka, and R. Selby. "Analysis of external and internal influences on CR agrarian foreign trade." Agricultural Economics (Zemědělská ekonomika) 57, No. 9 (2011): 422–35. http://dx.doi.org/10.17221/137/2010-agricecon.

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The agrarian sector has a non-substitutable position in most world economics &ndash; including the CR. From the viewpoint of functioning of own agrarian trade it can be stated that the CR is roughly self-sufficient by 70&ndash;80% in products of a competitive nature. In case of products of a non-competitive nature, the CR shows almost zero self-sufficiency. It means that agrarian foreign trade occupies a non-substitutable position in the CR economy (at least from the export point of view). In the light of our own trade flows, the CR performs as an active exporter and importer (about 100 billion and 130&nbsp;billion CZK respectively, in 2009). However, together with the still growing needs of the national economy and the inhabitants&rsquo; requirements for a varied composition of agri‑food products, the CR does not succeed in the long term to decrease the negative balance of the agrarian foreign trade. It is, however, indisputable that if a serious discussion should be held about the competitiveness of Czech agriculture in confrontation with foreign producers or suppliers of agricultural and food products, the priority task to reach a balanced agrarian foreign trade balance can be accepted only for the competitive products segment. The complexity of a greater participation of the basic Czech agricultural and food products on the EU unified market deepens simultaneously with the acceleration of the liberalisation process on this market. The gradual process of the world agrarian market liberalisation then means that the cost and price relationships are determined by such world producers as are able to offer agrarian products for the most advantageous prices, or offer goods of exceptional quality, with a high added value, brand products, national specialties and so on. Potentially, the space for improvement of the active balance of agrarian foreign trade (AFT) is given to us in much the same way as to our competitors, but actually, our possibilities are limited. The stagnation or even growth of the negative AFT balance was, and is influenced by non-substitutable imports of non-competitive food raw materials and foodstuff products and many other raw materials required by the non-agricultural sectors of the national economy.

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Xia, Daping, Song Huang, and Huaiwen Zhang. "Transformation analysis of key liquid phase products during lignite fermentation to produce biological hydrogen." Natural Gas Industry B 7, no. 2 (2020): 168–75. http://dx.doi.org/10.1016/j.ngib.2019.08.001.

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Breyer, Viola, Matthias Frischmann, Clemens Bidmon, Annelen Schemm, Katrin Schiebel, and Monika Pischetsrieder. "Analysis and biological relevance of advanced glycation end-products of DNA in eukaryotic cells." FEBS Journal 275, no. 5 (2008): 914–25. http://dx.doi.org/10.1111/j.1742-4658.2008.06255.x.

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Alborov, Rolan, Lyudmila Khoruzhy, Stanislava Kontsevaya, and Gregory Kontsevoy. "Management aspects of accounting for biological assets and agricultural products." Buhuchet v sel'skom hozjajstve (Accounting in Agriculture), no. 6 (June 1, 2020): 8–18. http://dx.doi.org/10.33920/sel-11-2006-01.

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Agricultural activity is a strategic direction of the work of agricultural organizations, ensuring food independence and security of the country. In this regard, in modern conditions there is an objective need to improve the management of biotransformation of biological assets and its accounting and control functions. The work defines the objects of management and accounting of agricultural activity: biological assets; agricultural products; income, expenses and financial results from biotransformation of biological assets; government grant related to a biological asset measured at fair value less costs to sell. Recommendations are proposed on the determination and analysis of changes in the fair value of biological assets less costs to sell due to changes in unit prices and the amount of these assets. In addition, methodological aspects of monitoring the effectiveness of the use of biological assets and the production of agricultural products collected from them are identified. Each of these indicators provides indicative indicators, methods of calculation and comparison with similar indicators of the base period or planning. The following are methods for determining individual indicators from the proposed system that allow organization managers at all levels of internal management to make scientifically sound economic decisions to improve the efficiency of the processes of biological transformation of biological assets and agricultural production in agricultural organizations.

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Al-Dhabi, Naif Abdullah. "Heavy metal analysis in commercial Spirulina products for human consumption." Saudi Journal of Biological Sciences 20, no. 4 (2013): 383–88. http://dx.doi.org/10.1016/j.sjbs.2013.04.006.

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Steenkamp, J. E. B. M., B. Wierenga, and M. T. G. Meulenberg. "Analysis of food quality perception processes." Netherlands Journal of Agricultural Science 34, no. 2 (1986): 227–30. http://dx.doi.org/10.18174/njas.v34i2.16808.

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A study was made to investigate ways in which consumers perceive the quality of food products and a model of the quality perception process was developed. Consumers used intrinsic (colour and appearance of product) and extrinsic (price and brand name) factors to determine rating of a product on quality aspects that cannot be evaluated at point of purchase (such as taste). The model was used on 13 foods and a high score for a food quality variable (nutritive value, energy content, additives and sensory quality) indicates that this quality is perceived as important. Energy content of meat, cheese, minced meat, margarine and meat products is perceived as most important indicator of quality. A high score for additives in jams, canned and jarred vegetables indicates that these products are perceived as poor quality. (Abstract retrieved from CAB Abstracts by CABI’s permission)

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Hellwig, Michael. "Analysis of Protein Oxidation in Food and Feed Products." Journal of Agricultural and Food Chemistry 68, no. 46 (2020): 12870–85. http://dx.doi.org/10.1021/acs.jafc.0c00711.

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Tang, Wei. "The Status of Biological Research and Prospect Analysis of Asphalt." Applied Mechanics and Materials 744-746 (March 2015): 1547–50. http://dx.doi.org/10.4028/www.scientific.net/amm.744-746.1547.

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Due to the current over-exploitation and use of oil resources imminent danger of being exhausted, petroleum bitumen from oil, the problem of oil resources and environmental development of the current situation forces us to constantly look for and application of new, renewable alternative materials. Currently, the world's best research and development of biomass energy is an inexhaustible renewable energy. This paper researches on biological asphalt collect summary summarizes the current research status of biological asphalt, aggregate its application in road engineering performance, analyze their development, application prospects. Current research indicates that biological asphalt bitumen is an efficient alternative to petroleum products, to enhance road performance while conserving resources better.

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Kubíčková, L., and V. Šerhantová. "Analysis of changes in meat and meat products consumption in the Czech Republic in the past ten years." Agricultural Economics (Zemědělská ekonomika) 51, No. 9 (2012): 395–401. http://dx.doi.org/10.17221/5126-agricecon.

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In the past ten years, meat and meat products consumption has changed dramatically. It has been caused by price and non-price factors. This article gives a brief recapitulation of the development of the consumption of meat and meat products and identifies the key factors which, in the past ten years, have had a major impact on this development. This article presents results of the secondary data analysis and the results of an inquiry into meat and meat products consumer behaviour carried out in the late 2004.

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Krutyakova, V. "Concept of production development strategy biological plant protection products." Mehanization and electrification of agricultural, no. 10(109) (2019): 210–19. http://dx.doi.org/10.37204/0131-2189-2019-10-22.

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The purpose. Increase of biologization level of agriculture in Ukraine on the basis of working out of the development strategy concept of regional networks of the enterprises on manufacture of plants biological protection frames. Methods. The researches were carried out on the basis of the analysis of the current state, necessary literary sources and existing normative-legal documents on the issues of biologization of agriculture in Ukraine. The results. The concept of formation and development of the strategy of regional networks of enterprises for the production of agriculture biologization means, which consists of four blocks: target block – reducing the impact of chemicals on crop production and the environment; forecast-analytical block – determining the structure of crops, the volume of production; block of environmental factors – determining where it is possible to replace chemicals with biological ones; conceptual block – assessment of the possibility of creating a system of biofactories and laboratories and the solution of the problem. In order to implement the strategy for the production of crop biologization agents, the following scenario of development of entomological and microbiological industry is proposed: organizational direction, economic direction, technical and technological direction, normative and legal direction. The paper also proposes the stages of implementation of the scenario of the industry development for the production of plant breeding biologization means: partial modernization of existing production facilities; large-scale investment development of the direction. Conclusions 1.The offered concept of strategy of development of entomological and microbiological industry for biological protection of plants is a necessary condition of development of organic agriculture, maintenance of manufacture of high-quality organic production and essential reduction of influence of chemical methods of struggle against wreckers on an ecological condition of environment. Such concept should be immediately introduced in Ukraine. 2.As a result of implementation of tasks on development of serial production of technological equipment for equipping of biological production, reconstruction, technical re-equipment and creation of new biological factories and biolaboratories the dynamics of increase in production of means of agriculture biologization is predicted. Keywords: biologization of agriculture, entomologist and microbiological industry, concept, development strategy, regulatory framework.

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Herzon, Seth. "Emergent Properties of Natural Products." Synlett 29, no. 14 (2018): 1823–35. http://dx.doi.org/10.1055/s-0037-1610242.

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Emergence is the phenomenon by which novel properties arise from the combination of simpler fragments that lack those properties at their given levels of hierarchal complexity. Emergence is a centuries-old concept that is commonly invoked in biological systems. However, the penetration of this idea into chemistry, and studies of natural products in particular, has been more limited. In this article I will describe how the perspective of emergence provided a framework to elucidate the complex properties of two classes of natural products – the diazofluorene antitumor agent lomaiviticin A and the genotoxic bacterial metabolites known as colibactins, and sets the stage for a third class of molecules – antibiotics derived from the fungal metabolite pleuromutilin. Embracing the idea of emergence helped us to connect the aggregate reactivities of the colibactins and lomaiviticin A with their biological phenotypes. Emergence is a top-down approach to natural products and complements the classical bottom-up analysis of functional group structure and reactivity. It is a useful intellectual framework to study the complex evolved properties of natural products.1 Introduction2 Diazofluorenes3 Precolibactins and Colibactins4 Pleuromutilins5 Discussion and Conclusion

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OLIVEIRA, MAILCAR F., TELMA L. G. LEMOS, MARCOS C. DE MATTOS, TACIANA A. SEGUNDO, GILVANDETE M. P. SANTIAGO, and RAIMUNDO BRAZ-FILHO. "New enamine derivatives of lapachol and biological activity." Anais da Academia Brasileira de Ciências 74, no. 2 (2002): 211–21. http://dx.doi.org/10.1590/s0001-37652002000200004.

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A convenient synthesis of the new enamine derivatives 2-(4-morpholinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione, 2-(1-piperidinyl)-3-(3-methyl-2-butenyl)-1,4-naphtalenedione and 2-(1-pyrrolidinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione was carried out from natural 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione (lapachol) and morpholine, piperidine and pyrrolidine. The structures of the products were established mainly by NMR analysis, including 2D experiments. Biological activities of these products were evaluated against Artemia salina, Aedes aegypti and cytotoxicity using A549 human breast cells.

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Zhang, Qi, James R. Doroghazi, Xiling Zhao, Mark C. Walker, and Wilfred A. van der Donk. "Expanded Natural Product Diversity Revealed by Analysis of Lanthipeptide-Like Gene Clusters in Actinobacteria." Applied and Environmental Microbiology 81, no. 13 (2015): 4339–50. http://dx.doi.org/10.1128/aem.00635-15.

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ABSTRACTLanthionine-containing peptides (lanthipeptides) are a rapidly growing family of polycyclic peptide natural products belonging to the large class of ribosomally synthesized and posttranslationally modified peptides (RiPPs). Lanthipeptides are widely distributed in taxonomically distant species, and their currently known biosynthetic systems and biological activities are diverse. Building on the recent natural product gene cluster family (GCF) project, we report here large-scale analysis of lanthipeptide-like biosynthetic gene clusters fromActinobacteria. Our analysis suggests that lanthipeptide biosynthetic pathways, and by extrapolation the natural products themselves, are much more diverse than currently appreciated and contain many different posttranslational modifications. Furthermore, lanthionine synthetases are much more diverse in sequence and domain topology than currently characterized systems, and they are used by the biosynthetic machineries for natural products other than lanthipeptides. The gene cluster families described here significantly expand the chemical diversity and biosynthetic repertoire of lanthionine-related natural products. Biosynthesis of these novel natural products likely involves unusual and unprecedented biochemistries, as illustrated by several examples discussed in this study. In addition, class IV lanthipeptide gene clusters are shown not to be silent, setting the stage to investigate their biological activities.

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Živělová, I., J. Jánský, and T. Koudelková. "The analysis of contemporary markets with selected organic products in the Czech Republic and in selected foreign countries." Agricultural Economics (Zemědělská ekonomika) 50, No. 9 (2012): 417–22. http://dx.doi.org/10.17221/5227-agricecon.

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The paper aims to analyse the contemporary situation on markets with selected organic products in the Czech Republic as well as in selected European countries. The attention is paid especially to the share of organic products&acute; consumption (cereals, potatoes, fruits, vegetables, milk, pork, poultry and eggs) in the total food consumption in the Czech Republic, in Spain, in Sweden, in the Netherlands and in Great Britain.

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Silva de Oliveira, Mônica, Jorianne Thyeska Castro Alves, Pablo Henrique Caracciolo Gomes de Sá, and Adonney Allan de Oliveira Veras. "PAN2HGENE–tool for comparative analysis and identifying new gene products." PLOS ONE 16, no. 5 (2021): e0252414. http://dx.doi.org/10.1371/journal.pone.0252414.

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Advances in next-generation sequencing (NGS) platforms have had a positive impact on biological research, leading to the development of numerous omics approaches, including genomics, transcriptomics, metagenomics, and pangenomics. These analyses provide insights into the gene contents of various organisms. However, to understand the evolutionary processes of these genes, comparative analysis, which is an important tool for annotation, is required. Using comparative analysis, it is possible to infer the functions of gene contents and identify orthologs and paralogous genes via their homology. Although several comparative analysis tools currently exist, most of them are limited to complete genomes. PAN2HGENE, a computational tool that allows identification of gene products missing from the original genome sequence, with automated comparative analysis for both complete and draft genomes, can be used to address this limitation. In this study, PAN2HGENE was used to identify new products, resulting in altering the alpha value behavior in the pangenome without altering the original genomic sequence. Our findings indicate that this tool represents an efficient alternative for comparative analysis, with a simple and intuitive graphical interface. The PAN2HGENE have been uploaded to SourceForge and are available via: https://sourceforge.net/projects/pan2hgene-software

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Sato, Michio, Haruka Yamada, Kinya Hotta, and Kenji Watanabe. "Elucidation of the shanorellin biosynthetic pathway and functional analysis of associated enzymes." MedChemComm 6, no. 3 (2015): 425–30. http://dx.doi.org/10.1039/c4md00352g.

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Since fungal natural products biosynthesized by polyketide synthases frequently exhibit useful biological activities, identifying and understanding the mechanism of biosynthetic steps taken by PKSs are of great interest.

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Sarria, A., J. Arcos, J. Tellez, and N. Calle. "PBI7 CASE STUDY: ECONOMICAL ANALYSIS OF WASTE IN BIOLOGICAL PRODUCTS IN AN INSTITUTION IN COLOMBIA." Value in Health Regional Issues 19 (October 2019): S12. http://dx.doi.org/10.1016/j.vhri.2019.08.063.

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Silva, Ana Rita M., and J. M. F. Nogueira. "New approach on trace analysis of triclosan in personal care products, biological and environmental matrices." Talanta 74, no. 5 (2008): 1498–504. http://dx.doi.org/10.1016/j.talanta.2007.09.040.

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Wu, Joseph, Anindita Banerjee, Bo Jin, Sandeep M. Menon, Steven W. Martin, and Anne C. Heatherington. "Clinical dose–response for a broad set of biological products: A model-based meta-analysis." Statistical Methods in Medical Research 27, no. 9 (2017): 2694–721. http://dx.doi.org/10.1177/0962280216684528.

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Characterizing clinical dose–response is a critical step in drug development. Uncertainty in the dose–response model when planning a dose-ranging study can often undermine efficiency in both the design and analysis of the trial. Results of a previous meta-analysis on a portfolio of small molecule compounds from a large pharmaceutical company demonstrated a consistent dose–response relationship that was well described by the maximal effect model. Biologics are different from small molecules due to their large molecular sizes and their potential to induce immunogenicity. A model-based meta-analysis was conducted on the clinical efficacy of 71 distinct biologics evaluated in 91 placebo-controlled dose–response studies published between 1995 and 2014. The maximal effect model, arising from receptor occupancy theory, described the clinical dose–response data for the majority of the biologics (81.7%, n = 58). Five biologics (7%) with data showing non-monotonic trend assuming the maximal effect model were identified and discussed. A Bayesian model-based hierarchical approach using different joint specifications of prior densities for the maximal effect model parameters was used to meta-analyze the whole set of biologics excluding these five biologics ( n = 66). Posterior predictive distributions of the maximal effect model parameters were reported and they could be used to aid the design of future dose-ranging studies. Compared to the meta-analysis of small molecules, the combination of fewer doses, narrower dosing ranges, and small sample sizes further limited the information available to estimate clinical dose–response among biologics.

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Kim, Jin-Ah, Sung-Deuk Lee, Kwang-Ho Hwang, et al. "Bacterial Contamination Reduction of Minimally Processed Agricultural Products using Antibacterial Foods and Molecular Biological Analysis." Journal of Food Hygiene and Safety 31, no. 1 (2016): 8–14. http://dx.doi.org/10.13103/jfhs.2016.31.1.8.

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OMURA, S., A. TAYA, S. MASUDA, H. NAITOU, N. OHASHI, and N. KINAE. "Biological Response of Advanced Glycation End Products to the Established Cell Line and Proteome Analysis." Annals of the New York Academy of Sciences 1043, no. 1 (2005): 908. http://dx.doi.org/10.1196/annals.1333.122.

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Jaksch, Frank L., and Savaş Tay. "Editorial overview: Analytical biotechnology: New technologies for quantitative analysis of biological specimens and natural products." Current Opinion in Biotechnology 25 (February 2014): iv—vi. http://dx.doi.org/10.1016/j.copbio.2013.12.005.

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Spickett, Corinne. "Lipid oxidation products induce specific protein modifications: biological effects and analysis by LC-MS/MS." Free Radical Biology and Medicine 165 (March 2021): 15–16. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.287.

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Vitkova, Tsvetelina G., Rositsa K. Enikova, and Mariyana R. Stoynovska. "MEDICAL EVALUATION OF THE POTENTIAL BIOLOGICAL AND CHEMICAL DANGERS IN HIGH-RISK FOODS." Journal of IMAB - Annual Proceeding (Scientific Papers) 27, no. 3 (2021): 3924–29. http://dx.doi.org/10.5272/jimab.2021273.3924.

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Purpose: The current European legislation assigned the responsibility for food safety to the food producers and traders. In this aspect, the aim of the survey was to provide critical analysis of the functioning of Hazard Analysis and Critical Control Point (HACCP) systems in the production of foods, presenting certain risks of specific public health hazards - foodborne toxicoinfections, infections and intoxications, for chemical contamination and additives, etc. The survey covered HACCP-systems and prerequisite programmes of 4 enterprises manufacturing confectionery products, ready-to-serve foods, pasteurized egg products, sterilized canned foods. Material/methods: Monitoring and critical analysis of the In-plant control system and HACCP of four enterprises for the production of: confectionery products, ready-to-serve-dishes in public catering, sterilized canned foods, pasteurized egg semi-ready products Results: The current experience has revealed major defects in hazard analysis, adequacy of critical points, corrective actions and verification procedures. The article contains recommendations and suggestions for improving the work of manufacturers and harmonizing relationships with regulatory authorities in the event of inconsistencies in production. Conclusions: The authors concluded that a comprehensive medical evaluation of the HACCP systems was necessary for the prevention of foodborne diseases.

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Savoiskyi, Oleksandr, Valerii Yakovliev, and Viktor Sirenko. "COMPARATIVE ANALYSIS OF METHODS SUPPLIES THERMAL ENERGY IN HIGH-WATER BIOLOGICAL OBJECTS DURING DRYING." ScienceRise, no. 1 (February 27, 2021): 3–10. http://dx.doi.org/10.21303/2313-8416.2021.001667.

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Object of research: the process of heating a biological object with various methods of supplying thermal energy, in particular, convective, direct electric and combined methods. Solved problem: intensification of heating of high-moisture biological objects during the drying process. Main scientific results. The expediency of using a combined (direct electric and convective) supply of thermal energy for intensifying heating of raw materials in the drying process has been established. In terms of the duration of the heating process, combined heating is much more effective than using purely convective or direct electric heating. Comparison of the values of the duration of the heating process for a body weighing 0.0028 kg shows that the combined heating occurs 1.5–2.5 times faster. At the same time, the consumption of electrical energy for the selected processing modes is 279–254 J, which is 80–87 % of the total required energy. It has been found that the main control factor in the combined heat supply is the applied voltage of direct electric heating. The area of practical application of the research results: enterprises of the processing industry, specializing in the production of dried products. Innovative technological product: a combined method of heating high-moisture objects during the drying process, which will provide intensive and energy-efficient processing modes while maintaining the established quality of the finished product. Scope of application of the innovative technological product: production of finished food products and semi-finished products.

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Nghi, Do Huu, and Le Mai Huong. "APPLICATION OF IMAGE-BASED HIGH CONTENT ANALYSIS FOR THE SCREENING OF BIOACTIVE NATURAL PRODUCTS." Vietnam Journal of Science and Technology 56, no. 4A (2018): 1. http://dx.doi.org/10.15625/2525-2518/56/4a/13065.

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Each bioactive compound induces phenotypic changes in target cells that can be made visible by labelling selected molecules of the cells with fluorescent dyes and/or directly observed under the high-throughput microscope. A comparison of the cellular phenotype induced by a compound of interest with known cellular targets allows predicting its mode of action. Over the past 15 years, high-throughput microscopy has been one of the fastest growing fields in cell biology. When combined with automated multiparametric image and data analysis, it is referred to as high-content screening (HCS). Whilst HCS has been successfully applied to the bioactivity characterization of natural products, recent studies used automated microscopy and software to increase speed and to reduce subjective interpretation. In 2017, Institute of Natural Products Chemistry (INPC-VAST) has been equipped with a HCS platform (Olympus Scan^R) that designed for fully automated image acquisition and analysis of biological samples to visually inspect the cellular morphology induced by hit compounds as well as to discriminate from false positives. Accordingly, this short review covers the concepts of HCS and its application in screening of biologically active natural products whose molecular targets could be identified through such approaches.

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