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Dissertations / Theses on the topic 'Biologické struktury'

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1

Vlachová, Hutová Eliška. "STUDIUM ZMĚN VLASTNOSTÍ BIOLOGICKÝCH MATERIÁLŮ V ELEKTROMAGNETICKÝCH POLÍCH." Doctoral thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2021. http://www.nusl.cz/ntk/nusl-447546.

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Presented dissertation discusses the influence of electromagnetic fields on the weight of the particles, which are considered in this work as substances with the hub. Theoretical knowledge was practically tested on plant organisms (early somatic embryos, fungal pathogens), theoretically the influence of electromagnetic field on cell structure was modeled. It was subsequently confirmed by a practical experiment assumption about the influence of electromagnetic fields on the weight of the particles. These experiments were preceded by a theoretical study of the problem and the formulation of a so
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Muchová, Johana. "Vliv biologicky aktivních látek na strukturu a vlastnosti kolagenových substrátů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2016. http://www.nusl.cz/ntk/nusl-240589.

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Diplomová práce se zabývá přípravou 3D porézních kolagenových skafoldů metodou lyofilizace a jejich modifikací bioaktivními látkami. K modifikaci byly použity přírodní polysacharidy – chitosan, vápenatá oxidovaná celulóza a chitin/chitosan-glukanový komplex. Mechanické vlastnosti skafoldů byly upraveny síťováním pomocí karbodiimidů. Růstové faktory byly dodány formou destičkového lyzátu. Byl zkoumán vliv biologicky aktivních aditiv, siťovacího činidla a obohacení růstovými faktory na vlastnosti připravených skaffoldů a jejich bioaktivitu v tkáních živých organismů. Konkrétně byly studovány mor
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Ručková, Jana. "Studium přípravy a struktury nanovláken anorganických a organických biomateriálů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2014. http://www.nusl.cz/ntk/nusl-217080.

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The aim of this Master’s thesis is to investigate the preparation and structure of nanofibres of inorganic and organic biomaterials. Nanofibres of polycaprolactone, chitosane and their composites with hydroxyapatite particle were prepared by centrifugal force spinning process, which uses centrifugal forces for nanofibres spinning. Designed nanofibres can be used in bone tissue engineering. Experimental activity has started with synthesis of hydroxyapatite nanoparticles and preparation of polymer solutions and composite suspensions at different concentrations. The solutions and the suspensions
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Vintonyak, Viktor. "Syntheses and biological evaluation of Cruentaren A and neopeltolide as well as their analogues." [S.l. : s.n.], 2008.

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5

Söderlund, Leo. "Hårfollikelns struktur, funktion och hårpigmenteringens genetiska reglering hos däggdjuren : Samt hur detta kan användas som modell i gymnasieksolan för att ge en djupare förståelse för genetiska interaktioner." Thesis, Linköpings universitet, Institutionen för fysik, kemi och biologi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-172138.

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Hårfollikeln är en struktur som hittas hos alla däggdjur. Hår skyddar kroppen från UV-ljus, medverkar i kroppens värmereglering och har flera kommunikativa funktioner. Hårets varierande färg inom och mellan arter är både en fascinerande och intresseväckande egenskap som länge har studerats som en modell för genetisk nedärvning. I denna litteraturstudie ges en genomgång av hårfollikelns struktur och funktion, genetiken bakom hårets pigmentering samt didaktiska utmaningar i genetikundervisningen. Interaktioner mellan generna MC1R, ASIP (agouti) och POMC förklaras och exemplifieras. Dessutom disk
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David, Jan. "Produkce, charakterizace a návrh aplikací regenerovaných huminových kyselin." Doctoral thesis, Vysoké učení technické v Brně. Fakulta chemická, 2011. http://www.nusl.cz/ntk/nusl-233322.

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Předkládaná disertační práce se zabývá huminovými látkami (HL), zejména huminovými kyselinami a jejich solemi, tj. humáty. V práci je prezentována literární rešerše o huminových látkách, stručně je zmíněna historie výzkumu huminových látek, obsáhle jsou pak prezentovány práce o jejich struktuře a supramolekulovém uspořádání. Jsou též zmíněny metody extrakce huminových látek z různých zdrojů. Dále jsou v tomto pojednání zařazeny a diskutovány práce zabývající se biologickými „hormonálními“ vlastnostmi HL. Z hlediska chemie životního prostředí jsou zmíněny zejména sorpční vlastnosti HL. Popsané
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Theorin, Gunilla. "Landskapsanalys av ett odlingslandskap : En studie av förändring i struktur och småbiotopers utbredning sedan 50-talet." Thesis, Uppsala universitet, Kulturgeografiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-167494.

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Matulík, Martin. "Modelování a animace biologických struktur." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2018. http://www.nusl.cz/ntk/nusl-377662.

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Following work deals with subject matter of digital modelling and animation of biological structures. Software tools for computer generated images (CGI), well proven in common practice, are evaluated, as well as tools for specific activities, available inside chosen software environment. Among vast pool of modelling approaches are discussed tools suitable for creation and representation of selected structures, along with tools essential for their consequent animation. Possible rendering approaches and their parameters in relation to qualities of resulting computer-generated images are discusse
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Lidija, Jevrić. "Ispitivanje korelacije između hemijske strukture, fizičko-hemijskih i retencionih parametara u hromatografiji na obrnutim fazama novosintetisanih derivata s-triazina." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2009. https://www.cris.uns.ac.rs/record.jsf?recordId=73285&source=NDLTD&language=en.

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Primenom tečne hromatografije na obrnutim fazamaispitano je retenciono pona&scaron;anje 14 novosintetisanihderivata s-triazina na tankom sloju RP C-18 i silika geluimpregniranim parafinskim uljem. Kao pokretne fazekori&scaron;ćene su dvokomponentne sme&scaron;e vode i organskihrastvarača. Izračunate su R<sub>M</sub><sup>0&nbsp;</sup>vrednosti i ispitana jekorelacija sa različitim deskriptorima i prediktorimabiolo&scaron;ke aktivnosti.<br>Retentional behaviour of 14newly syntetised derivates&nbsp;of s-triazine on RP C-18 and paraffin oil-impregnated&nbsp;silica gel suport had been investigated
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Ljubica, Grbović. "Izolovanje, strukturna karakterizacija i biološka aktivnost naftnih kiselina iz Vojvođanske nafte." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2009. http://dx.doi.org/10.2298/NS20091204GRBOVIC.

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Grupno-strukturna analiza naftnih kiselina izolovanih iz srednjih uljnih&nbsp;komercijalnih frakcija vojvođanske nafte &bdquo;Velebit&rdquo; rađena je analizom IR-,&nbsp;<sup>1</sup>H- i&nbsp;<sup>13</sup>C NMR- i ESI-MS spektara niske rezolucije. Određeno je &scaron;est klasa&nbsp;karboksilnih kiselina op&scaron;te molekulske formule C<sub>n</sub>H<sub>2n-Z</sub>O<sub>2</sub>. To su karboksilne&nbsp;kiseline u opsegu masa 240-466 sa 15-31 C atoma u molekulu koje su&nbsp;grupisane u pet cikloalkil Z-serija: monociklična- (C<sub>n</sub>H<sub>2n-2</sub>O<sub>2</sub>, 14.72%),&nbsp;biciklična- (C
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Kraft, Veronica. "Grön infrastruktur och naturvärden i tätortsnära skog : Analys och åtgärdsförslag för Hallaholm i Åtvidaberg." Thesis, Linnéuniversitetet, Institutionen för biologi och miljö (BOM), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-105125.

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Trenden för biologisk mångfald i världen är negativ och skogslevande arter är inget undantag. I denna studie undersöks den tätortsnära, kommunägda skogen Hallaholm i Åtvidaberg, Östergötland. Studien fastställer vilka naturtyper som finns i skogens olika delar och delområdena bedöms utifrån förekomst av de rödlistade arterna ekticka och tallticka samt av fasta strukturer som död ved, lavbeväxta träd, vedsvampar och hålträd. Därtill görs en bedömning av vilken betydelse områdets olika naturtyper har för regionens gröna infrastruktur. Naturtyperna är huvudsakligen ädellöv, triviallöv, tall, gran
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Jožef, Mađari. "Sinteza, strukturna, fizičko-hemijska i biološka karakterizacija novih N-heterocikličnih liganada i njihovih kompleksa sa jonima prelaznih metala." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2018. https://www.cris.uns.ac.rs/record.jsf?recordId=107656&source=NDLTD&language=en.

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Opisane&nbsp; su&nbsp; sinteze&nbsp; novih&nbsp; liganada&nbsp; bis(ftalazin-1hidrazon)-2,6-diacetilpiridna&nbsp; (Hz<sub>2</sub>DAP&middot;2HCl),&nbsp; bis(3-hlorpiridazin-6-hidrazon)-2,6-diacetilpiridina (Hp<sub>2</sub>DAP),&nbsp; 3-hlorpiridazin-6-hidrazon&nbsp; di(2-piridil) ketona&nbsp; (HpDPK),&nbsp; ftalazin-1-hidrazon&nbsp; di(2-piridil)ketona&nbsp; (HzDPK)&nbsp; i&nbsp; ftalazin-1-hidrazon&nbsp; piridin-2-karbaldehida&nbsp; (HzPY).&nbsp; Zajedničko&nbsp; svojstvo&nbsp; dobijenih liganada&nbsp; je&nbsp; &scaron;to&nbsp; sadrže&nbsp; piridinski&nbsp; i&nbsp; diazinski&nbsp; prsten&nbsp;
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Senka, Popović. "Istraživanje dobijanja i karakterizacija biorazgradivih kompozitnih filmova na bazi biljnih proteina." Phd thesis, Univerzitet u Novom Sadu, Tehnološki fakultet Novi Sad, 2013. https://www.cris.uns.ac.rs/record.jsf?recordId=83221&source=NDLTD&language=en.

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Predmet doktorske disertacije je ispitivanje mogućnosti karakterizacija novih biorazgradivih kompozitnih filmova nabazi biljnih proteina. Osnovno istraživanje se bazira naispitivanju mogućnosti dobijanja kompozitnih filmova na baziobnovljivih sirovina, vlažnim postupkom (&quot;casting&quot; metoda),karakterizaciji dobijenih filmova i modifikaciji uslova dobijanjaradi pobolj&scaron;anja osobina formiranog filma. Istraživanja sezasnivaju na dobijanju filmova na bazi pogače uljane tikvegolice (Cucurbita pepo L. c. v. Olinka) (pumpkin oil cake &ndash;PuOC), njenog proteinskog izolata i njihove kom
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Ksenija, Pavlović. "Mikrotalasno stimulisane transformacije prirodnih i sintetičkih karboksilnih kiselina i njihovih derivata." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2014. https://www.cris.uns.ac.rs/record.jsf?recordId=87883&source=NDLTD&language=en.

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Predviđena istraživanja u ovoj doktorskoj disertaciji su usmerena u pravcu&nbsp;modifikacije klasičnih metoda i postupaka za transformaciju karboksilne grupe&nbsp;prirodnih i sintetičkih karboksilnih kiselina. Modifikacije su rađene novim,&nbsp;savremenim, ekonomski i ekolo&scaron;ki opravdanim metodama rada u&nbsp;mikrotalasnom reaktoru. Modifikovanim sintetskim postupcima u&nbsp;mikrotalasnom reaktoru urađena je sinteza amida, hidroksamskih&nbsp; derivata,&nbsp;kao i redukcija individualnih naftnih kiselina i&nbsp; sme&scaron;e&nbsp; prirodnih naftnih kiselina&nbsp;&bdquo;Velebit&ldquo; do a
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Suchá, Kateřina. "Hodnocení kvality/zdraví půdy v blízkosti obce Bohaté Málkovice." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2019. http://www.nusl.cz/ntk/nusl-392022.

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Diploma thesis evaluates quality and healthiness of the soil health located close to Bohate Malkovice focusing on changes in both physical and chemical characteristics of the soil in time. The theoretical part describes physical, chemical, and biological parameters of the soil. Selected physical parameters are structure, texture, determination of measured weight, bulk density of the soil, porosity, actual volumetric water content of the soil, aeration, saturated and unsaturated hydraulic conductivity, infiltration, and colour. Chosen chemical parameters are pH, carbonates, soil electrical cond
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Zanzi, Ferrando Diana. "Surrogatmodern och den mänskliga värdigheten : En diskursanalys av den statliga utredningen om surrogatmoderskap, ur ett kritiskt postkolonialt feministiskt perspektiv." Thesis, Uppsala universitet, Statsvetenskapliga institutionen, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-390148.

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Uppsatsen undersöker hur ”SOU 2016:11 Olika vägar till föräldraskap” formulerar problemet med surrogatmoderskap, vilka subjektspositioner som kan urskiljas i utredningen och analyserar den ut ett kritiskt postkolonialt feministiskt perspektiv.   Utredningen utgår ifrån mänsklig värdighet, autonomi och barnets bästa vilket uppsatsen belyser får konsekvenser för hur problemet med surrogatarrangemang porträtteras olika beroende på om surrogatmodern och barnet är från det globala syd eller det globala nord. Utgångspunkterna är centrala när surrogatmodern och barnet från det globala nord lyfts men
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Rozbeský, Daniel. "Studium struktury a biologické funkce myších NKR-P1 receptorů." Doctoral thesis, 2013. http://www.nusl.cz/ntk/nusl-322612.

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Natural killer (NK) cells play a significant role in the detection and destruction of virally infected and tumor cells. The NKR-P1 receptors regulate NK cell function by an alternative missing-self recognition system. Although the NKR-P1 receptors were among the first surface NK receptors identified on rodent NK cells more than 20 years ago, there is still very little known about their biological function and their physiological ligands. Furthermore, no three-dimensional structure of any of the NKR-P1 family receptors has been published so far. To understand the functional architecture of mous
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KOTLANOVÁ, Kristina. "Možnosti techniky AFLP ve studiu genetické struktury populací Beauveria bassiana." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-53290.

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Beauveria bassiana is widely used in biological control against the economically significant pests. Detection of morphological and genetic polymorphism among single species and strains in natural environment is important to study of the distribution and the effects in the ecosystem. The aim of this study was to determine the links of "local strains" with ecological aspects of biological control in protected zone of National park and assess the polymorphism of the population monitored in NP Šumava and exotic strains using molecular markers. There were analyzed 39 strains collected in the NP Šum
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Matoušek, Mikuláš. "Výpočty elektronové struktury biologicky relevantních komplexů přechodných kovů." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-415411.

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Porphyrins are an important class of biomolecules, which are heavily studied, both ex- perimentally and computationally. But, despite the intensive efforts, for many questions we still aren't able to consistently find an agreement between theory and experiment. One of the still unresolved issues is the character of the ground state of the Fe(II)-porphyrin molecule. We used a model of the Fe(II)-porphyrin molecule to study the effects of geometrical changes on the spin states. By carrying out extensive DMRG-CASSCF cal- culations topped with TCCSD correlation treatment we are able to link the ef
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Hanusová, Petra. "Alkaloidy čeledi Amaryllidaceae: isolace, strukturní identifikace, biologická aktivita. III." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-361790.

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Hanusová P.: Alkaloids of Amaryllidaceae family: isolation, structural identification, biological activity. III. Diploma thesis, Charles University, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Botany and Ecology, Hradec Králové, 2017. For phytochemical study was selected plant cultivar Narcissus cv. PROFESSOR EINSTEIN. The aim of the work was to isolate Amaryllidaceae alkaloids in pure form and screening of their biological activities. Summary alkaloidal extract was prepared from 34 kg of fresh bulbs and separated by column chromatography. Preparative TLC and crystalliz
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Dohnalová, Alice. "Alkaloidy čeledi Amaryllidaceae: isolace, strukturní identifikace, biologická aktivita. I." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-361794.

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Dohnalova A: Alkaloids of Amaryllidaceae family: isolation, structural identification, biological activity. I; Diploma thesis, Charles University, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Botany and Ecology, Hradec Králové, 2017, 64 p. The Amaryllidaceae family includes bulbous, beautifully flowering plants that have been used for thousands of years in traditional medicine. The major chemical compounds found in this particular plant family are alkaloids, namely Amaryllidaceae alkaloids. Until now, more than 500 isoquinoline alkaloids have been discovered, which exhib
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Kohelová, Eliška. "Alkaloidy čeledi Amaryllidaceae: isolace, strukturní identifikace, biologická aktivita. II." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-379168.

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Kohelová E: Alkaloids of Amaryllidaceae family: isolation, structural identification, biological activity. II Diploma thesis, Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Botany and Ecology, Hradec Králové, 2017, 77p. The aim of the diploma thesis was a preparation of alkaloidal extract from fresh bulbs of Narcissus cv. PROFESSOR EINSTEIN to izolate two Amaryllidaceae alkaloids by column and thin layer chromatography. Subsequently these alkaloids were subjected to structural MS and NMR analysis and tested for biological activity against huma
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Černá, Kateřina. "Alkaloidy čeledi Amaryllidaceae: isolace, strukturní identifikace, biologická aktivita. IV." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-405164.

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Perennial plants from the Amaryllidaceae family are generally known for their beauty but also like herbs which contain wide range of alkaloids. To these days more than 500 alkaloids have been isolated. Amaryllidaceae alkaloids (AmA) are derivatived from aminoacid tyrosine and divided into nine basic groups. Biological activity of these substances icludes antitumor, antibacterial, antifungal, antiviral, antimalarial activity and some of them are used for treatment Alzheimer's disease (AD). Narcissus cv. PROFESSOR EINSTEIN have been choosen thanks to previous research of summary extract. Twelve
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Al, Shammari Latifah Ajaj M. "Alkaloidy rodu Hippeastrum (Amaryllidaceae): izolace, strukturní identifikace, biologická aktivita." Doctoral thesis, 2021. http://www.nusl.cz/ntk/nusl-445960.

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Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Botany Candidate: MSc. Latifah Al Shammari Supervisor: Prof. Ing. Lucie Cahlíková, Ph.D. Title of Doctoral Thesis: Alkaloids of the genus Hippeastrum (Amaryllidaceae): isolation, identification, biological activity. Hippeastrum x hybridum cv. Ferrari was chosen based on results of previous screening studies for detailed phytochemical study for the purpose of isolation of the widest range of AAs. From 25 kg of fresh bulbs was obtained 29,46 g of purified alkaloidal extract, which was processed using
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Schickerová, Julie. "Alkaloidy Narcissus pseudonarcissus cv. Dutch Master: isolace, strukturní identifikace, příprava analog, biologická aktivita." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-387900.

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Schickerová Julie: Alkaloids of Narcissus pseudonarcissus cv. Dutch Master: isolation, structural identification, preparation of analogues, biological activity. Diploma thesis, Charles University, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Botany, Hradec Králové, 2018, 73 p. The purpose of this diploma thesis was to isolate the substances from the fraction ND 15- 9, which was obtained by column chromatography of the alkaloid extract of Narcissus pseudonarcissus cv. Dutch Master. The method of preparative TLC was used to separate this fraction, and the three purified co
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Espinoza, Herrera Shirly Josefina. "Úloha hořečnatých iontů při formování biologicky aktivních struktur nukleových kyselin." Doctoral thesis, 2011. http://www.nusl.cz/ntk/nusl-296115.

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ESPINOZA HERRERA S.J. - DOCTORAL THESIS - FUNCTION OF MAGNESIUM IONS IN THE FORMATION OF BIOLOGICALLY-ACTIVE NUCLEIC ACIDS STRUCTURES ____________________________________________________________________ ABSTRACT Interaction of magnesium ions, the divalent ions with the highest concentration inside living cells, with the key biomolecules of nucleic acids was studied with aim to find out structural details of the interaction mechanism and effect of the magnesium ions presence on the nucleic-acid structure and structural transitions. Raman spectroscopy was chosen as the main experimental method,
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Palacký, Jan. "Studium biologicky významných nekanonických struktur nukleových kyselin v komplexech s kationtickými porfyriny." Doctoral thesis, 2013. http://www.nusl.cz/ntk/nusl-328594.

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Guanine quadruplexes are a class of unusual nucleic acids conformations based on stacked planar guanine tetrads stabilized via Hoogsteen pairing and cation coordination. They are implicated in numerous cellular processes including replication, recombination or transcription. Guanine quadruplexes are widespread within the human genome but their occurrence is highest in the single stranded guanine-rich regions at telomeres. Telomeric guanine quadruplexes are gaining growing interest due to their ability to inhibit the activity of the telomerase enzyme, which is responsible for the proliferation
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Komlóová, Markéta. "Vztah mezi strukturou a biologickou aktivitou nových modulátorů acetylcholinesterasy." Doctoral thesis, 2012. http://www.nusl.cz/ntk/nusl-306320.

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Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department: Dpt. of Pharmaceutical Chemistry and Drug Control Student: Mgr. Markéta Komlóová Supervisor: prof. PharmDr. Martin Doležal, Ph.D. Title of Doctoral Thesis: Relationship between structure and biological activity of new modulators of acetylcholinesterase This work focuses on the preparation of peripherally acting AChE inhibitors as a potential treatment of myasthenia gravis. These compounds could also be used as a pre- treatment of poisoning by organophosphorus AChE inhibitors. They can occupy the active site of an e
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Nekvinda, Jan. "Syntéza nových karboranových matallakarboranových a strukturní bloků pro vývoj biologicky aktivní látek." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-333047.

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Compounds with carboxylic and amidic functions belong to basic structural blocks, which are used for construction of functional molecules in organic, organometallic and also in carborane chemistry. However, considering cobalt bis(dicarbollide)(1-) ion, the synthetic ways to these derivatives have been virtually unknown. A published procedure on lithiation in THF and reaction with CO2 leading to mono- and dicarboxylic acids had failed in our hands. Nevertheless, a detailed revision of the experimental conditions provided finally good yields of mixture of both acids, which could be separated by
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Klimentová, Jana. "Strukturní obměny transkarbamů - syntéza a sledování vlastností a biologické aktivity se zaměřením na objasnění mechanismu účinku." Doctoral thesis, 2006. http://www.nusl.cz/ntk/nusl-269944.

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One of the subjects studied in the Department of Inorganic and Organic Chemistry of the Faculty of Pharmacy focuses on the synthesis and biological evaluation of potential transdermal permeation enhancers. Over the past few years, series of esters of 6-aminohexanoic acid of high enhancing activity and their analogues have been prepared. Presently, the structure-activity relationships are being studied. This work contributes to this problem by searching for the mechanism of action of one of the most active compounds, transkarbam 12 (T12). Transdermal permeation enhancers facilitate drug absorpt
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31

Semelková, Lucia. "Příprava derivátů pyrazinu jako potenciálních antituberkulotik. (Studium vztahů mezi chemickou strukturou a biologickou aktivitou)." Doctoral thesis, 2017. http://www.nusl.cz/ntk/nusl-368840.

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Charles University, Faculty of Pharmacy in Hradec Králové Department: Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Candidate: Mgr. Lucia Semelková Supervisor: Prof. PharmDr. Martin Doležal, Ph.D. Consultant: PharmDr. Jan Zitko, Ph.D. Title of Doctoral Thesis: Preparation of Pyrazinamide Derivatives as Potential Antituberculotics (Study of Structure Activity Relationships) This doctoral thesis is focused on search for novel pyrazinamide derivatives with potential antitubercular activity. The theoretical part summarizes issues connected with tuberculosis and its epidemiolog
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Beck, Tobias. "Sticky triangles: New tools for experimental phasing of biological macromolecules." Doctoral thesis, 2010. http://hdl.handle.net/11858/00-1735-0000-0006-B083-2.

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Kessner, Doreen [Verfasser]. "Neutron scattering on biological subjects : neue Einblicke in die Struktur der Lipidmatrix des Stratum corneum, basierend auf Modellmembranen / von Doreen Kessner geb. Otto." 2008. http://d-nb.info/994698011/34.

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