Relevant bibliographies by topics / Bioluminescence resonance energy transfer / Dissertations / Theses
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Dissertations / Theses on the topic 'Bioluminescence resonance energy transfer'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 February 2022

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1

Ayoub, Mohammed Akli. "Etude de la dimérisation des récepteurs de la mélatonine par la technique de BRET : Bioluminescence Resonance Energy Transfer." Paris 11, 2003. http://www.theses.fr/2003PA11T043.

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2

Colin, Béatrice. "Développement d’un système rapporteur générique sensible, au double mode de lecture BRET/HCS, pour l’étude du suivi de gènes rapporteurs, de l’activité de protéase virale et des interactions protéine-protéine." Thesis, Lille 2, 2018. http://www.theses.fr/2018LIL2S050.

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De nombreux systèmes rapporteurs ont été développés pour répondre à différentes applications allant de l’étude des régions promotrices gouvernant l’expression de gènes au suivi de voies de signalisation ou encore à l’interaction de partenaires protéiques.Dans le but initial de développer un test d’activité protéase ayant une sensibilité accrue, nous avons mis au point un système rapporteur permettant l’amplification du signal en développant un système basé sur l’utilisation d’une enzyme relais hyperactive, la protéase TEV (Tobacco Etch Virus) qui vient couper une sonde protéique cible. La déte
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3

Borbas, K. Eszter. "Switchable luminescent probes using resonance energy transfer." Thesis, Open University, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412386.

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4

Torres, Garcia Juan de. "Nanophotonic control of Förster resonance energy transfer." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4354.

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Le transfert d'énergie par résonance de type Förster (FRET) permet de mesurer des distances nanométriques grâce à la dépendance critique de l'efficacité du transfert avec la séparation entre un donneur et un accepteur d'énergie. Le phénomène se produit quand le fluorophore donneur dans l'état excité transfère son énergie d'excitation à un accepteur à proximité de façon non-radiative avec une interaction dipôle-dipôle de champ proche. Les structures nanophotoniques sont capables de contrôler cette interaction grâce à la modification de la densité local d'états électromagnétiques (LDOS) d'un éme
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5

Leopold, Matthew. "Förster Resonance Energy Transfer in PbS Films." Bowling Green State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1408656943.

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6

Gatebe, Erastus G. "Fluorescence resonance energy transfer in conjugated organic nanostructures /." Available to subscribers only, 2007. http://proquest.umi.com/pqdweb?did=1456289291&sid=3&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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7

Martin, Sarah Friede. "Fluorescence resonance energy transfer studies of protein interactions." Thesis, St Andrews, 2008. http://hdl.handle.net/10023/537.

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8

Buscemi, Giuseppe. "Nanocrystals for resonance energy transfer and lasing applications." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/426882/.

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The work at hand is structured into four chapters, the first of which is this introduction. An appendix explains a small experiment on a different topic of research that differs from the core of this thesis. The second chapter explains the physics of semiconductor crystals and semiconductor nanostructures. Introduces the mathematical framework to describe the exciton in semiconductor nanostructures. Chapter three outlines the mechanism of RET and is dedicated to the experimental and theoretical methods we employed during our research. We present the technique that has allowed us to perform a R
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9

Domin, Alexander. "Fluorescence resonance energy transfer analysis in living cells." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614141.

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10

Blagoi, Gabriela. "Fluorescence resonance energy transfer (FRET) based sensors for bioanalysis." ScholarWorks@UNO, 2004. http://louisdl.louislibraries.org/u?/NOD,146.

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Thesis (Ph. D.)--University of New Orleans, 2004.<br>Title from electronic submission form. "A dissertation ... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry."--Dissertation t.p. Vita. Includes bibliographical references.
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11

Chong, Ee Zhuan. "Experimental investigation of fluorescence resonance energy transfer using quantum dots." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/54612/.

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Quantum dots (QDs) are light emitting nanoscale semiconductor crystals with novel optical properties that are markedly different from the conventional organic dyes. Their size tunable emission, broad absorption and resistance to photo- and chemical degradation have afforded a new route to biomolecular studies, especially in long term live cell imaging that is hardly feasible with the utility of organic dyes. With the advent of highly luminescent core-shell QDs with quantum yields over 0.5, sensitive and robust optical sensing assays can be realised in which organic dyes rarely have much succes
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12

Rustomji, Kaizad. "Controlling spontaneous emission and resonance energy transfer : an antenna analogy." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0032/document.

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Le facteur de Purcell mesure l'augmentation ou la diminution du taux d'émission spontanée. Il a été démontré que dans un régime de couplage faible, le facteur Purcell est analogue à la modification de l'impédance d’entrée d’une antenne radiofréquence. Nous avons utilisé cette approche de mesure de l’impédance d'antenne afin de déterminer le facteur de Purcell dans un méta matériau entre 5-15 GHz. Le méta matériau, en raison de sa dispersion hyperbolique en polarisation transverse magnétique a une densité d'état local importante qui se traduit par une augmentation du facteur Purcell. En même te
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13

Balloi, Eleonora. "Investigating conformational changes of proteins using Förster Resonance Energy Transfer." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/investigating-conformational-changes-of-proteins-using-frster-resonance-energy-transfer(fd5f53e7-9464-40bf-9c87-6fbd0a3d8804).html.

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Förster Resonance Energy Transfer (FRET)-based techniques are gaining an increasing importance in cell biology and cell-matrix adhesion studies because they allow both the detection of conformational changes of target proteins and their localisation in cells. Frequency Domain-Fluorescence Lifetime Microscopy (FD-FLIM) is currently considered one of the most reliable methods to measure FRET in live cells. However, due to its dependence on many technical prerequisites, its use is not yet widespread. The purpose of this work was to first establish FD-FLIM measurements of FRET on a new FD-FLIM mi
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14

Brossard, Mael. "Novel paradigms for resonance energy transfer mediated hybrid photovoltaic devices." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/386232/.

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This work focuses on the utilisation of quantum dots (QDs) and resonance energy transfer to enhance the properties of existing photovoltaic technologies. Time-resolved spectroscopy is used to demonstrate that lead sulphide (PbS) QDs could be used to enhance the absorptivity of silicon solar cells. In this scheme, QDs deposited on the solar cell act as absorber, while the photogenerated excitons are transferred to the underlying silicon to contribute to the photocurrent. QD hybridization is also demonstrated in InGaP solar cells. In this case, the QDs are used to mitigate the poor utilisation o
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15

Rindermann, Jan Junis. "On the prospect of resonance energy transfer for hybrid optoelectronics." Thesis, University of Southampton, 2012. https://eprints.soton.ac.uk/355470/.

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16

Dennis, Allison Marie. "Quantum dot-fluorescent protein pairs as fluorescence resonance energy transfer pairs." Diss., Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/37079.

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Fluorescence resonance energy transfer (FRET)-based biosensors have been designed to fluorometrically detect everything from proteolytic activity to receptor-ligand interactions and structural changes in proteins. While a wide variety of fluorophores have demonstrated effectiveness in FRET probes, several potential sensor components are particularly notable. Semiconductor quantum dots (QDs) are attractive FRET donors because they are rather bright, exhibit high quantum yields, and their nanoparticulate structure enables the attachment of multiple acceptor molecules. Fluorescent proteins (FPs)
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17

Hildebrandt, Nico, Loïc Charbonnière, Raymond F. Ziessel, and Hans-Gerd Löhmannsröben. "Quantum dots as resonance energy transfer acceptors for monitoring biological interactions." Universität Potsdam, 2006. http://opus.kobv.de/ubp/volltexte/2007/1221/.

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Quantum dots (QDs) are common as luminescing markers for imaging in biological applications because their optical properties seem to be inert against their surrounding solvent. This, together with broad and strong absorption bands and intense, sharp tuneable luminescence bands, makes them interesting candidates for methods utilizing Forster Resonance Energy Transfer (FRET), e. g. for sensitive homogeneous fluoroimmunoassays (FIA). In this work we demonstrate energy transfer from Eu3+-trisbipyridin (Eu-TBP) donors to CdSe-ZnS-QD acceptors in solutions with and without serum. The QDs are commerc
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18

Holdich, Jonathan Peter. "Assessment of Gαq-coupled receptor activation using fluorescence resonance energy transfer". Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612154.

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19

Green, J. "Studying the human telomeric intramolecular quadruplex using fluorescence resonance energy transfer." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599658.

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The work described here involves the use of fluorescence measurements to investigate the intramolecular quadruplex formed by the human telomeric repeat. By monitoring the efficiency of energy transfer between fluorophores either side of the structure, it is possible to follow the opening of the quadruplex in real time. In many of the experiments described here this opening was induced by the addition of a strand complementary to the quadruplex-forming sequence, to form a conventional duplex structure. Initial studies focused on the rate of opening of the human telomeric intramolecular quadrupl
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20

Mu, Chunyao Jenny. "Fluorescence resonance energy transfer-based biosensors for monitoring prostate specific antigen." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/32360.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005.<br>Includes bibliographical references (leaves 72-78).<br>Prostate cancer has become the most commonly diagnosed cancer in men in the United States. Clinical diagnostic procedures currently include prostate-specific antigen (PSA) screening, digital rectal exam, and prostatic needle biopsy. However, these methods lack the sensitivity to detect small lesions that occur in the early stages of cancer and metastasis. I propose a molecular imaging modality that provides a biochemical characterization of loca
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21

Ramsay, Douglas Francis. "Resonance energy transfer based detection of G-protein coupled receptor dimerization." Thesis, University of Glasgow, 2002. http://theses.gla.ac.uk/30854/.

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Over the past decade there has been a growing body of evidence, obtained from studies employing a wide variety of pharmacological, biochemical and biophysical techniques, suggesting that G protein coupled receptors (GPCRs) exist not as monomeric entities but rather as dimers or other higher order oligomeric arrays. To further the accumulation of knowledge pertaining to this research area, the work presented in this thesis has made use of one such particular biophysical technique called bioluminescence resonance energy transfer (BRET). In order to utilise this system GPCRs were modified at thei
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22

Guo, Jiajia. "Time-resolved Multiplexed Förster Resonance Energy Transfer for Nucleic Acid Biosensing." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS162/document.

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Les biomarqueurs à base d’acides nucléiques, qui sont impliqués dans le contrôle de l'expression génétique, sont spécifiques de nombreux types de cancers. Les applications basées sur le transfert d'énergie par résonance de Förster (FRET) sont parmi les plus prometteuses pour la biodétection d’acides nucléiques. Comme la détection simultanée de plusieurs acides nucléiques est très demandée et que le multiplexage spectral est limité par des interférences (optical crosstalk), le multiplexage temporel est utilisé ici pour ajouter de nouvelles possibilités de multiples détections simultanées. La th
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23

Xu, Jin. "Conformational Studies of Myosin and Actin with Calibrated Resonance Energy Transfer." Thesis, University of North Texas, 2000. https://digital.library.unt.edu/ark:/67531/metadc2438/.

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Resonance energy transfer was employed to study the conformational changes of actomyosin during ATP hydrolysis. To calibrate the technique, the parameters for resonance energy transfer were defined. With conformational searching algorithms to predict probe orientation, the distances measured by resonance energy transfer are highly consistent with the atomic models, which verified the accuracy and feasibility of resonance energy transfer for structural studies of proteins and oligonucleotides. To study intramyosin distances, resonance energy transfer probes were attached to skeletal myosin's
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24

Karhu, Robin. "Targeted Energy Transfer in Bose-Einstein Condensates." Thesis, Linköpings universitet, Teoretisk Fysik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-98279.

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Targeted Energy Transfer is a resonance phenomenon in coupled anharmonic oscillators. In this thesis we investigate if the concept of Targeted Energy Transfer is applicable to Bose-Einsteain condensates in optical lattices. The model used to describe Bose-Einstein condensates in optical lattices is based on the Gross-Pitaevskii equation. Targeted Energy Transfer in these systems would correspond to energy being transferred from one lattice site to another. We also try to expand the concept of Targeted Energy Transfer to a system consisting of three sites, where one of the sites are considered
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25

Thomson, Cameron Ian. "Probing the Nature of Cellulosic Fibre Interfaces with Fluorescence Resonance Energy Transfer." Diss., Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/16277.

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The material properties of fibre networks and fibre reinforced composites are strongly influenced by fibre-fibre interactions. Stress transfer between load bearing elements in such materials is often dictated by the nature of the fibre-fibre interface. Inter-fibre bonding is solely responsible for internal cohesion in paper, because all stresses transferred between fibres operate through fibre-fibre bonds. . The future development of cellulosic fibre materials will require an improved understanding of the fibre-fibre interface. Fluorescence resonance energy transfer (FRET) was proposed as a
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26

Li, Xuelian. "USING CONJUGATED POLYMERS AS BIOLOGICAL SENSOR BASED ON FLUORESCENCE RESONANCE ENERGY TRANSFER." OpenSIUC, 2011. https://opensiuc.lib.siu.edu/dissertations/321.

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J E. coli On-Off &ldquo, &rdquo, °, &ndash The specific objectives of the work presented in this dissertation are to design novel molecular sensors based on fluorescence resonance energy transfer (FRET) between fluorophore (donor) and polydiacetylene (PDA, acceptor) for selective detection of biomolecules in solution. The work described in this dissertation is divided into three sections. In the first section, we report here two novel systems where the rate of energy transfer is based on changes in the spectral overlap between the emission of the donor and the absorption of the acceptor (J) as
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27

Merckx, R., Thomas Swift, R. Rees, et al. "Förster resonance energy transfer in fluorophore labeled poly(2-ethyl-2-oxazoline)s†." Royal Society of Chemistry, 2020. http://hdl.handle.net/10454/18374.

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Yes<br>Dye-functionalized polymers have been extensively studied to understand polymer chain dynamics, intra or inter-molecular association and conformational changes as well as in practical applications such as signal amplification in diagnostic tests and light-harvesting antennas. In this work, the Förster resonance energy transfer (FRET) of dye-functionalized poly(2-ethyl-2-oxazoline) (PEtOx) was studied to evaluate the effect of dye positioning and polymer chain length on the FRET efficiency. Therefore, both α (initiating terminus)- or ω (terminal chain end)-fluorophore single labeled and
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28

Xu, Jingyue. "Sensitive and mutiplexed microRNA quantification using amplified time-gated Förster resonance energy transfer." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASS137.

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En tant que biomarqueurs de nouvelle génération, les microARNs sont associés à de nombreux cancers et maladies, ce qui a conduit à une forte demande pour le développement de méthodes cliniques de diagnostic des microARNs. Les technologies d'amplification isotherme, telles que l'amplification en cercle roulant et l'assemblage catalytique en épingle à cheveux, sont devenues des méthodes puissantes pour les dosages très rapides, spécifiques et sensibles des microARNs. Cette thèse se concentre sur le développement de biocapteurs de microARNs basés sur les technologies d'amplification isotherme et
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29

Wu, Yu-Tang. "Förster Resonance Energy Transfer Immunoassays Using Engineered Proteins for Breast Cancer Biomarker Detection." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS340/document.

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Les protéines modifiées ont suscité un grand intérêt en raison de leur taille extrêmement petite par rapport à l'anticorps entier. Ces petites protéines de liaison ont démontré de nombreux avantages tels qu'une bio distribution rapide, une bonne pénétration dans le tissu tumoral et une élimination rapide du sérum et des tissus non-infectés. Ainsi, ces protéines devraient être d'excellentes alternatives aux anticorps pour les applications cliniques. Cette thèse présente le développement de biocapteurs basés sur des anticorps synthétiques et le transfert d'énergie par résonance de type Förster (
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30

Grant, David Mitchell. "Multi-dimensional fluorescence microscopy for Förster resonance energy transfer studies of cell signaling." Thesis, Imperial College London, 2008. http://hdl.handle.net/10044/1/8012.

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This thesis discusses the development of novel multi-dimensional fluorescence microscopy, particularly fluorescence lifetime imaging (FLIM) technology, and its application to imaging Förster Resonance Energy Transfer (FRET) events in live cells. Particular emphasis is placed on imaging activation of Ras family GTP-ases and binding to their effectors, including Phospholipase C Epsilon (PLCε). The early part of the thesis discusses FLIM-FRET experiments performed using a standard confocal microscope with time correlated single photon counting (TCSPC) to image interactions between PLCε and Ras. T
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31

Wallace, Mark Ian. "A study of DNA conformational dynamics using single-molecule fluorescence resonance energy transfer." Thesis, University of Cambridge, 2001. https://www.repository.cam.ac.uk/handle/1810/251799.

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32

Sproll, Tobias. "A theoretical framework for waveguide quantum electrodynamics and its application to resonance energy transfer." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät, 2016. http://dx.doi.org/10.18452/17668.

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Diese Doktorarbeit beschäftigt sich mit theoretischen Aspekten der Wellenleiterelektrodynamik (WQED), also mit der Wechselwirkung von Materie und Licht, welches nur in einer Dimension propagieren kann. Dieses Forschungsfeld erfreut sich seit seiner Entstehung in den 1990er Jahren wachsender Beliebtheit, der Grund hierfür sind die mannigfaltigen Anwendungsmöglichkeiten, beispielsweise bei der Konstruktion von Quantencomputern als auch von klassischen Computern. Auch Vorschläge für sogenannte Pump-Probe-Experimente auf der Basis der WQED sind Gegenstand der aktuellen Forschung.\\ All diese Gebi
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33

Wang, Charlie Wang. "High Energy Phosphate Metabolism Measurement by Phosphorus-31 Magnetic Resonance Fingerprinting." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1509364666422789.

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34

Muschielok, Adam. "Development and application of a quantitative analysis method for fluorescence resonance energy transfer localization experiments." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-135739.

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35

Shabardina, Victoria [Verfasser], and Volker [Akademischer Betreuer] Gerke. "Conformational changes in ezrin analyzed by Förster resonance energy transfer / Victoria Shabardina ; Betreuer: Volker Gerke." Münster : Universitäts- und Landesbibliothek Münster, 2015. http://d-nb.info/1139845217/34.

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36

Sargenti, Charles. "A structure and function investigation of the E.coli Hsp70 DnaK using fluorescence resonance energy transfer /." Diss., Digital Dissertations Database. Restricted to UC campuses, 2004. http://uclibs.org/PID/11984.

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37

Wren, David Andrew. "Measuring calcium in Pseudomonas aeruginosa using a genetically encoded fluorescence resonance energy transfer (FRET) sensor." Connect to online resource, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1460883.

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38

Booker, Annette Casandra. "Optical Characterization and Evaluation of Dye-Nanoparticle Interactions." Thesis, Virginia Tech, 2006. http://hdl.handle.net/10919/36370.

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Surface plasmon resonance has become a widely investigated phenomenon in the past few years. Initially descriptive of light interactions with metallic films, research has branched out to encompass the nanoparticles as well. Generation of the maximum surface plasmon resonance for nanostructures is based on the resonance condition that the oscillatory behavior of the 'free' electrons on the surface of the particle become equivalent to the frequency of the excitation light; for films this required a specific geometry. Metallic nanoparticles have also interested researchers because of thei
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39

Stevens, Amy L. "Energy transfer processes in supramolecular light-harvesting systems." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:43833f3a-96b0-432a-9608-8f08a9096be7.

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This dissertation attempts to understand how energy transfer in a molecular wire and a spherical organic assembly are affected by molecular structure. The molecular wire is a DNA-hybrid structure composed of a strand of thymine bases appended by a cyanine dye. Hydrogen bonded to each base is a naphthalene-derivative molecule. Using time-integrated photoluminescence and time-correlated single photon counting measurements, energy transfer from the naphthalene donors to the cyanine acceptors was confirmed, and its dependence on temperature and DNA-template length investigated. Donor-thymine bondi
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40

Jonah, Olutola. "Optimization of Wireless Power Transfer via Magnetic Resonance in Different Media." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/876.

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A wide range of non-destructive testing (NDT) methods for the monitoring the health of concrete structure has been studied for several years. The recent rapid evolution of wireless sensor network (WSN) technologies has resulted in the development of sensing elements that can be embedded in concrete, to monitor the health of infrastructure, collect and report valuable related data. The monitoring system can potentially decrease the high installation time and reduce maintenance cost associated with wired monitoring systems. The monitoring sensors need to operate for a long period of time, but se
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41

Hildebrandt, Niko. "Lanthanides and quantum dots : time-resolved laser spectroscopy of biochemical Förster Resonance Energy Transfer (FRET) systems." Phd thesis, Universität Potsdam, 2006. http://opus.kobv.de/ubp/volltexte/2007/1268/.

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Förster Resonance Energy Transfer (FRET) plays an important role for biochemical applications such as DNA sequencing, intracellular protein-protein interactions, molecular binding studies, in vitro diagnostics and many others. For qualitative and quantitative analysis, FRET systems are usually assembled through molecular recognition of biomolecules conjugated with donor and acceptor luminophores. Lanthanide (Ln) complexes, as well as semiconductor quantum dot nanocrystals (QD), possess unique photophysical properties that make them especially suitable for applied FRET. In this work the possibi
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42

Hildebrandt, Niko. "Lanthanides and quantum dots time-resolved laser spectroscopy of biochemical Förster resonance energy transfer (FRET) systems /." [S.l.] : [s.n.], 2006. http://opus.kobv.de/ubp/volltexte/2007/1268.

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43

Olejko, Lydia [Verfasser], and Ilko [Akademischer Betreuer] Bald. "Förster resonance energy transfer (FRET)-based nanophotonics using DNA origami structures / Lydia Olejko ; Betreuer: Ilko Bald." Potsdam : Universität Potsdam, 2017. http://d-nb.info/1218402261/34.

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44

Fotheringham, Helen L. "Investigation of ligand-induced conformational changes of the dopamine D2s receptor using fluorescence resonance energy transfer." Thesis, University of Reading, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558734.

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Approximately 50 % of current pharmaceutical drugs target the G protein-coupled receptor (GPCR) family, rendering an understanding of the mechanisms behind their actions critical. Dopamine is a key neurotransmitter involved in motor function and behaviour and has been associated with disorders such as Parkinson's disease and schizophrenia. Within the present study, a Fluorescence Resonance Energy Transfer (FRET)-based conformational change sensor was created to study dopamine D2S receptor responses to ligands to gain an understanding of the mechanisms underlying ligand-induced activation. Chim
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McNaghten, Edward Dennison. "Some studies of gas phase vibrational energy transfer processes using the IR-UV double resonance technique." Thesis, Queen's University Belfast, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329391.

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46

Bouchard, Véronique. "Identification de la nucléoline comme protéine pouvant interagir avec la poly(ADP-ribose) polymérase-1 par spectrométrie de masse et caractérisation de cette association par bioluminescence resonance energy transfer (BRET) /." 2003. http://proquest.umi.com/pqdweb?did=766571361&sid=23&Fmt=2&clientId=9268&RQT=309&VName=PQD.

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47

Armando, Sylvain. "Structure quaternaire des récepteurs de chimiokines CXCR4 et CCR2 et interaction avec leurs effecteurs." Thèse, 2010. http://hdl.handle.net/1866/4888.

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Les récepteurs couplés aux protéines G (RCPG) sont une famille très diversifiée de protéines membranaires capables de répondre à un grand nombre de signaux chimiques tels que des photons, des molécules odorantes, ou des hormones. En plus de cette diversité, l’étude des RCPG montre que des associations protéiques spécifiques multiplient les possibilités de signalisation de chacun de ces récepteurs. En permettant d’atténuer, de potentialiser, ou de générer une nouvelle voie de signalisation, l’association des RCPG en oligomères s’avère une importante source de diversité. L’utilisation du transfe
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48

Breton, Billy. "Étude moléculaire de la formation de complexes protéiques impliqués dans la signalisation des récepteurs couplés aux protéines G." Thèse, 2010. http://hdl.handle.net/1866/3975.

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Abstract:
La communication cellulaire est un phénomène important pour le maintien de l’homéostasie des cellules. Au court des dernières années, cette sphère de recherche sur la signalisation cellulaire a connue des avancées importantes au niveau de l’identification des acteurs principaux impliqués dans la reconnaissance extracellulaire des signaux, ainsi que la compréhension des voies de signalisation engagées par les cellules pour répondre aux facteurs extracellulaires. Malgré ces nouvelles informations, les diverses interrelations moléculaires entre les acteurs ainsi que les voies de signalisation cel
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49

Woo, Jongchan. "Application and Optimization of Bioluminescence Resonance Energy Transfer (BRET) for Real Time Detection of Protein-Protein Interactions in Transgenic Arabidopsis as well as Structure-Based Functional Studies on the Active Site of Coelenterazine-dependent Luciferase from Renilla and its Improvement by Protein Engineering." 2008. http://etd.utk.edu/2008/WooJongchan.pdf.

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50

Gravel, Stéphanie. "Évaluation de l'effet des antagonistes synthétiques du récepteur de chimiokine, CXCR4 sur CXCR7." Thèse, 2010. http://hdl.handle.net/1866/4290.

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Abstract:
RÉSUMÉ Le récepteur de chimiokine CXCR7 a été récemment identifié comme liant la chimiokine SDF-1, anciennement considérée comme ligand exclusif du récepteur CXCR4. Ces deux récepteurs sont exprimés majoritairement dans les mêmes types cellulaires et, ainsi, la découverte de CXCR7 incite à réévaluer les effets respectifs de SDF-1 sur CXCR4. Étant donné son rôle dans le cancer, CXCR4 est une cible de choix pour le développement de molécules thérapeutiques. Également, CXCR7 semble être impliqué dans la croissance tumorale. AMD3100, un antagoniste «sélectif» pour CXCR4, est maintenant commerciali
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