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Journal articles on the topic 'Biomaterials; Medical polymers; Bone implants'

Author: Grafiati

Published: 4 June 2021

Last updated: 3 February 2022

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1

Katsanevakis, Eleni, Xue Jun Wen, Dong Lu Shi, and Ning Zhang. "Biomineralization of Polymer Scaffolds." Key Engineering Materials 441 (June 2010): 269–95. http://dx.doi.org/10.4028/www.scientific.net/kem.441.269.

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Bioceramics are an important subclass of inorganic, non-metallic biomaterials. Attributing to their bioactivity and the ability to form bonds with native bone, bioceramics are increasingly used in medical implants, especially for bone repair and regeneration. With chemical composition similar to that of native bone, hydroxyapatite (HAp), a type of bioceramics, may impart to biomaterial implants biocompatibility, osteoconductivity, as well as surface properties that are germane to osteointegration at the bone-implant interface. However, porous bioceramics are very brittle and have low fracture

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Vojtěch, Dalibor, Jiří Kubásek, Jaroslav Čapek, and Iva Pospíšilová. "Novel Trends in the Development of Metallic Materials for Medical Implants." Key Engineering Materials 647 (May 2015): 59–65. http://dx.doi.org/10.4028/www.scientific.net/kem.647.59.

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Metallic biomaterials are currently used in medicine for fabrication of various kinds of implants like joint and bone replacements, dental implants, stents, fixation devices for fractured bones etc. Their advantages over polymeric or ceramic biomaterials are in higher strength, fracture toughness and fatigue life. In addition, metals can be simply processed by established technologies known for centuries. Due to the increasing average age of human population, there are growing requirements for mechanical and functional performance of implants. Therefore, extensive research and development acti

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Jackson, Nicolette, Michel Assad, Derick Vollmer, James Stanley, and Madeleine Chagnon. "Histopathological Evaluation of Orthopedic Medical Devices: The State-of-the-art in Animal Models, Imaging, and Histomorphometry Techniques." Toxicologic Pathology 47, no. 3 (2019): 280–96. http://dx.doi.org/10.1177/0192623318821083.

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Orthopedic medical devices are continuously evolving for the latest clinical indications in craniomaxillofacial, spine, trauma, joint arthroplasty, sports medicine, and soft tissue regeneration fields, with a variety of materials from new metallic alloys and ceramics to composite polymers, bioresorbables, or surface-treated implants. There is great need for qualified medical device pathologists to evaluate these next generation biomaterials, with improved biocompatibility and bioactivity for orthopedic applications, and a broad range of knowledge is required to stay abreast of this ever-changi

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4

James, Kenneth, and Joachim Kohn. "New Biomaterials For Tissue Engineering." MRS Bulletin 21, no. 11 (1996): 22–26. http://dx.doi.org/10.1557/s0883769400031808.

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The success of tissue engineering rests on the ability to direct specific cell types to multiply, migrate, and express normal physiologic behaviors in order to yield a cellular organization that performs the functions of the desired tissue. For example the engineering of living bone to repair skeletal defects has focused on growing osteoblasts—the cells responsible for bone formation—on degradable polymer matrices in vitro. The polymer matrix initially serves as the scaffold for bone-cell proliferation and maturation. Ideally the cells form a bonelike tissue that after implantation is fully in

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Mihai, Simona, and Viviana Filip. "New Design Concept for Reducing Torque Wear on Implant." Applied Mechanics and Materials 658 (October 2014): 453–58. http://dx.doi.org/10.4028/www.scientific.net/amm.658.453.

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The hip (coxofemoral) joint is built so as to provide, at the same time, maximum stability and mobility, and is characterized by a very low wear rate and very low frictional forces thanks to the very good natural lubrication. In time, due to various reasons such as aging, joint illnesses, bone tumors, arthritis, injuries, coxofemoral joints may lose their self-lubrication ability, causing pains that make movement almost impossible. The therapeutic solution for coxofemoral joint illnesses is hip implant arthroplasty. Medical implants replacing the bone segments of coxofemoral joints are subject

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Aversa, Raffaella, Roberto Sorrentino, and Antonio Apicella. "New Biomimetic Hybrid Nanocomposites for early Fixation Prostheses." Advanced Materials Research 1088 (February 2015): 487–94. http://dx.doi.org/10.4028/www.scientific.net/amr.1088.487.

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The research develops and tests new hybrid biomimetic materials that work as mechanically stimulating "scaffolds" to promote early regeneration in implanted bone healing phases. A biomimetic nanostructured osteoconductive material coated apparatus is presented. Bioinspired approaches to materials and templated growth of hybrid networks using self-assembled hybrid organic-inorganic interfaces is finalized to extend the use of hybrids in the medical field. Combined in vivo, in vitro and computer aided simulations have been carried out. A new experimental methodology for the identification of des

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Oriňaková, Renáta, Radka Gorejová, Zuzana Orságová Králová, and Andrej Oriňak. "Surface Modifications of Biodegradable Metallic Foams for Medical Applications." Coatings 10, no. 9 (2020): 819. http://dx.doi.org/10.3390/coatings10090819.

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Significant progress was achieved presently in the development of metallic foam-like materials improved by biocompatible coatings. Material properties of the iron, magnesium, zinc, and their alloys are promising for their uses in medical applications, especially for orthopedic and bone tissue purposes. Current processing technologies and a variety of modifications of the surface and composition facilitate the design of adjusted medical devices with desirable mechanical, morphological, and functional properties. This article reviews the recent progress in the design of advanced degradable metal

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Singh, Gurpreet, Yubraj Lamichhane, Amandeep Singh Bhui, Sarabjeet Singh Sidhu, Preetkanwal Singh Bains, and Prabin Mukhiya. "SURFACE MORPHOLOGY AND MICROHARDNESS BEHAVIOR OF 316L IN HAP-PMEDM." Facta Universitatis, Series: Mechanical Engineering 17, no. 3 (2019): 445. http://dx.doi.org/10.22190/fume190510040s.

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The development of biomaterials for implants nowadays requires materials with superior mechanical and physical properties for enhanced osseointegration and sustained longevity. This research work was conducted to investigate the influence of nano hydroxyapatite (HAp) powder mixed electrical discharge machining (PMEDM) on surface morphology and microhardness of modified 316L stainless steel surface. The chosen process parameters were discharge current, pulse on/off duration and gap voltage in order to analyze the selected output responses. HAp concentration (15 g/l) along with reverse polarity

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Ji, Yang, Xiaoming Yu, and Hao Zhu. "Fabrication of Mg Coating on PEEK and Antibacterial Evaluation for Bone Application." Coatings 11, no. 8 (2021): 1010. http://dx.doi.org/10.3390/coatings11081010.

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Polyetheretherketone (PEEK) is an alternative biomedical polymer material to traditional metal and ceramic biomaterials. However, as a bioinert material, its wide application in the medical field is seriously restricted due to its lack of bioactivity. In this research, pure Mg was successfully deposited on a PEEK substrate by vapor deposition to improve the antibacterial properties of PEEK implants. The morphology and elemental composition of the coating were characterized by scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS). The higher the deposition temperature, the

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de Groot, K., J. G. C. Wolke, and J. A. Jansen. "Calcium phosphate coatings for medical implants." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 212, no. 2 (1998): 137–47. http://dx.doi.org/10.1243/0954411981533917.

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In surgical disciplines where bone has to be repaired, augmented or improved, bone substitutes are essential. Although bone banks, such as Eurotransplant, are founded to supply such substitutes, natural bone is not always adequate. For example, frequently these so-called bone grafts resorb after implantation (1). Further, they cannot be used for joint and tooth replacement, and recently worries have been raised about the transfer of infectious diseases. Therefore, interest has dramatically increased in the use of synthetic materials for replacement of lost or damaged bone tissue. The generic n

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Kasir, Rafid, Varadraj N. Vernekar, and Cato T. Laurencin. "Inductive biomaterials for bone regeneration." Journal of Materials Research 32, no. 6 (2017): 1047–60. http://dx.doi.org/10.1557/jmr.2017.39.

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Inductive biomaterials are sought as alternatives to traditional materials used to treat bone defects. Traditional materials include autologous bone grafts that must be obtained surgically, and allografts that carry the risk of disease transmission and infection. Whereas the use of growth factors to stimulate bone growth has seen considerable advances, their efficacy is usually limited to supra-physiological doses with considerable side effects. On the other hand, certain biomaterials have an intrinsic ability to stimulate bone regeneration in lieu of growth factor use, and their use in repair

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Rico-Llanos, Gustavo A., Sara Borrego-González, Miguelangel Moncayo-Donoso, José Becerra, and Rick Visser. "Collagen Type I Biomaterials as Scaffolds for Bone Tissue Engineering." Polymers 13, no. 4 (2021): 599. http://dx.doi.org/10.3390/polym13040599.

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Collagen type I is the main organic constituent of the bone extracellular matrix and has been used for decades as scaffolding material in bone tissue engineering approaches when autografts are not feasible. Polymeric collagen can be easily isolated from various animal sources and can be processed in a great number of ways to manufacture biomaterials in the form of sponges, particles, or hydrogels, among others, for different applications. Despite its great biocompatibility and osteoconductivity, collagen type I also has some drawbacks, such as its high biodegradability, low mechanical strength

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TÖrmälä, P., T. Pohjonen, and P. Rokkanen. "Bioabsorbable polymers: Materials technology and surgical applications." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 212, no. 2 (1998): 101–11. http://dx.doi.org/10.1243/0954411981533872.

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Biostable and bioabsorbable biomaterials are used to manufacture implants for supporting, replacement, augmentation and guiding of growth of tissues. Bioabsorbable implants are a better choice for applications where only the temporary presence of the implant is needed. Because of bioabsorption of such implants, there is no need for a removal operation after healing of the tissue and the risks of implant related, long-term complications are eliminated or strongly reduced. Reinforcing of bioabsorbable materials is necessary in order to develop strong and safe, small implants for fixation of bone

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Cavalu, Simona. "Acrylic Bone Cements: New Insight and Future Perspective." Key Engineering Materials 745 (July 2017): 39–49. http://dx.doi.org/10.4028/www.scientific.net/kem.745.39.

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The history of acrylic bone cement comprise a long period of time, Sir John Charnley being considered the founder of modern artificial joint replacement, as he started to develop the cementing in the late 1950s. Acrylic bone cements (ACB) are polymer-ceramic composites based on polymethyl metacrylate (PMMA), widely used in orthopaedics as suture materials and fixation devices. The main features of these materials are: 1) biocompatibility and ability to support new bone growth (osteoconductive) and 2) bioactivity (ability to form a calcium phosphate layer on its surface). The main function of t

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Rokkanen, P., O. Böstman, E. Hirvensalo, et al. "Totally Biodegradable Implants for Bone Fixation and Ligament Repair." MRS Bulletin 25, no. 1 (2000): 21–24. http://dx.doi.org/10.1557/s0883769400064976.

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Synthetic biomaterials can be divided into metals, polymers, ceramics, and composites. Polymeric biomaterials and composites can be classified as biostable, partially biodegradable, or totally biodegradable. Biostable polymers are inert, cause minimal tissue response, and retain their properties for years. Because only a temporary supporting biomaterial is required in many clinical applications, totally or partially biodegradable polymeric materials are often better than biologically biostable materials.Biodegradation implies the degradation of a material induced by the activities of an organi

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Mohan, Dumitru, Valentin Munteanu, Horatiu Moisa, and A. V. Ciurea. "A Medical Insight on the of Biomaterials for Cranioplasty Surgery." Key Engineering Materials 638 (March 2015): 205–9. http://dx.doi.org/10.4028/www.scientific.net/kem.638.205.

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Cranioplasty represent surgical repairs of defects or deformities of the skull which may come as a result of trauma or congenital malformations. The notable advance in cranioplasties came with the experimental groundwork in bone grafting, performed in the late 19th century, based on which, the use of autografts for cranioplasty became popular in the early 20th century. With the First and Second World Wars alternative metals and plastics were needed to cover large cranial defects suffered in combat as precious metals became scarce. As time passed metallic bone substitutes have gradually become

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Singha, Balraj, Gurpreet Singh, and Buta Singh Sidhu. "Current Trends in Bio-Implants’ Research." Asian Journal of Engineering and Applied Technology 7, no. 2 (2018): 57–59. http://dx.doi.org/10.51983/ajeat-2018.7.2.955.

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Biomaterials are used for making devices that can interact with biological systems of peoples who not only suffers from congenital heart, bone or dental diseases but even sometime young and dynamic people such as sportspersons need replacements due to fracture and excessive strain. The biomaterials are commonly used in dentistry, orthopedics, plastic and reconstructive surgery, ophthalmology, cardiovascular surgery, neurosurgery, immunology, histopathology, experimental surgery, and veterinary medicine etc. Biomaterials when placed inside the human body are called bio-implants. In spite of the

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18

Lumbau, Aurea Immacolata, Silvio Mario Meloni, Marco Tallarico, et al. "Implant Placement Following Crestal Sinus Lift with Sequential Drills and Osteotomes: Five Years after Final Loading Results from a Retrospective Study." Journal of Functional Biomaterials 12, no. 1 (2021): 10. http://dx.doi.org/10.3390/jfb12010010.

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The aim of this retrospective study was to clinically evaluate the five-year outcomes of implants placed following a combined approach to the sinus, consisting of sequential drills and osteotomes. Medical records of patients with implants placed in combination with crestal sinus lift using sequential drills and osteotomes, with a residual alveolar bone crest between 4 to 8 mm, and a follow-up of at least five years after final loading, were evaluated. Outcomes were implant and prosthetic survival and success rates, any complication, and marginal bone loss. Data from 96 patients (53 women and 4

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Petrovova, Eva, Marek Tomco, Katarina Holovska, et al. "PHB/CHIT Scaffold as a Promising Biopolymer in the Treatment of Osteochondral Defects—An Experimental Animal Study." Polymers 13, no. 8 (2021): 1232. http://dx.doi.org/10.3390/polym13081232.

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Biopolymer composites allow the creation of an optimal environment for the regeneration of chondral and osteochondral defects of articular cartilage, where natural regeneration potential is limited. In this experimental study, we used the sheep animal model for the creation of knee cartilage defects. In the medial part of the trochlea and on the medial condyle of the femur, we created artificial defects (6 × 3 mm2) with microfractures. In four experimental sheep, both defects were subsequently filled with the porous acellular polyhydroxybutyrate/chitosan (PHB/CHIT)-based implant. Two sheep had

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20

Tanodekaew, Siriporn, Somruethai Channasanon, and Pakkanun Kaewkong. "Heat-curing polylactide for bone implants: Preparation and investigation on properties relevant to degradation." Journal of Bioactive and Compatible Polymers 34, no. 6 (2019): 464–78. http://dx.doi.org/10.1177/0883911519881715.

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Several processes have been used to produce polylactide for bone replacement. The challenge remains, however, to produce these devices by a simpler and more economical process. In this study, a method of combining powder and liquid parts was introduced. Star-shaped polylactides with molecular weights ranging from 3 to 16 kg/mol were synthesized and blended with a linear polylactide (Mw = 188 kg/mol) using the technique of emulsion solvent evaporation. The blends in a form of spherical powder were characterized by scanning electron microscopy, gel permeation chromatography, and particle size an

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Gugliandolo, Agnese, Luigia Fonticoli, Oriana Trubiani, et al. "Oral Bone Tissue Regeneration: Mesenchymal Stem Cells, Secretome, and Biomaterials." International Journal of Molecular Sciences 22, no. 10 (2021): 5236. http://dx.doi.org/10.3390/ijms22105236.

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In the last few decades, tissue engineering has become one of the most studied medical fields. Even if bone shows self-remodeling properties, in some cases, due to injuries or anomalies, bone regeneration can be required. In particular, oral bone regeneration is needed in the dentistry field, where the functional restoration of tissues near the tooth represents a limit for many dental implants. In this context, the application of biomaterials and mesenchymal stem cells (MSCs) appears promising for bone regeneration. This review focused on in vivo studies that evaluated bone regeneration using

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Zeng, Qiang, Yiwen Zhu, Bingran Yu, et al. "Antimicrobial and Antifouling Polymeric Agents for Surface Functionalization of Medical Implants." Biomacromolecules 19, no. 7 (2018): 2805–11. http://dx.doi.org/10.1021/acs.biomac.8b00399.

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Wöltje, Michael, Ronny Brünler, Melanie Böbel, et al. "Functionalization of Silk Fibers by PDGF and Bioceramics for Bone Tissue Regeneration." Coatings 10, no. 1 (2019): 8. http://dx.doi.org/10.3390/coatings10010008.

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Bone regeneration is a complex, well-organized physiological process of bone formation observed during normal fracture healing and involved in continuous remodeling throughout adult life. An ideal medical device for bone regeneration requires interconnected pores within the device to allow for penetration of blood vessels and cells, enabling material biodegradation and bone ingrowth. Additional mandatory characteristics include an excellent resorption rate, a 3D structure similar to natural bone, biocompatibility, and customizability to multiple patient-specific geometries combined with adequa

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Scarano, Antonio, Tiziana Orsini, Fabio Di Carlo, Luca Valbonetti, and Felice Lorusso. "Graphene-Doped Poly (Methyl-Methacrylate) (Pmma) Implants: A Micro-CT and Histomorphometrical Study in Rabbits." International Journal of Molecular Sciences 22, no. 3 (2021): 1441. http://dx.doi.org/10.3390/ijms22031441.

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Background—the graphene-doping procedure represents a useful procedure to improve the mechanical, physical and biological response of several Polymethyl methacrylate (PMMA)-derived polymers and biomaterials for dental applications. The aim of this study was to evaluate osseointegration of Graphene doped Poly(methyl methacrylate) (GD-PMMA) compared with PMMA as potential materials for dental implant devices. Methods—eighteen adult New Zealand white male rabbits with a mean weight of approx. 3000 g were used in this research. A total of eighteen implants of 3.5 mm diameter and 11 mm length in GD

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Navarro, M., A. Michiardi, O. Castaño, and J. A. Planell. "Biomaterials in orthopaedics." Journal of The Royal Society Interface 5, no. 27 (2008): 1137–58. http://dx.doi.org/10.1098/rsif.2008.0151.

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At present, strong requirements in orthopaedics are still to be met, both in bone and joint substitution and in the repair and regeneration of bone defects. In this framework, tremendous advances in the biomaterials field have been made in the last 50 years where materials intended for biomedical purposes have evolved through three different generations, namely first generation (bioinert materials), second generation (bioactive and biodegradable materials) and third generation (materials designed to stimulate specific responses at the molecular level). In this review, the evolution of differen

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Gao, Xing, Manon Fraulob, and Guillaume Haïat. "Biomechanical behaviours of the bone–implant interface: a review." Journal of The Royal Society Interface 16, no. 156 (2019): 20190259. http://dx.doi.org/10.1098/rsif.2019.0259.

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In recent decades, cementless implants have been widely used in clinical practice to replace missing organs, to replace damaged or missing bone tissue or to restore joint functionality. However, there remain risks of failure which may have dramatic consequences. The success of an implant depends on its stability, which is determined by the biomechanical properties of the bone–implant interface (BII). The aim of this review article is to provide more insight on the current state of the art concerning the evolution of the biomechanical properties of the BII as a function of the implant's environ

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Trevisan, Francesco, Flaviana Calignano, Alberta Aversa, et al. "Additive manufacturing of titanium alloys in the biomedical field: processes, properties and applications." Journal of Applied Biomaterials & Functional Materials 16, no. 2 (2017): 57–67. http://dx.doi.org/10.5301/jabfm.5000371.

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The mechanical properties and biocompatibility of titanium alloy medical devices and implants produced by additive manufacturing (AM) technologies – in particular, selective laser melting (SLM), electron beam melting (EBM) and laser metal deposition (LMD) – have been investigated by several researchers demonstrating how these innovative processes are able to fulfil medical requirements for clinical applications. This work reviews the advantages given by these technologies, which include the possibility to create porous complex structures to improve osseointegration and mechanical properties (b

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Gill, Rana. "A Bibliometric Analysis and Visualisation of Research Trends in Toxicity of Chromium Implants." Turkish Journal of Computer and Mathematics Education (TURCOMAT) 12, no. 2 (2021): 126–30. http://dx.doi.org/10.17762/turcomat.v12i2.689.

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The toxicity of implants is a vital factor affecting the safety of implants. The bibliometric analysis had been conducted to understand the active authors, organizations, journals, and countries involved in the research domain of “toxicity of Chromium implants”. All published articles related to “toxicity of Chromium implants” from “Scopus”, were analyzed using the VOS viewer to develop analysis tables and visualization maps. This article had set the objective to consolidate the scientific literature regarding “toxicity of Chromium implants” and also to find out the trends related to the same.

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Kawatra, Rahul, and Puneet Maheshwari. "A comparative study of surgical outcomes of ossiculoplasty using biomaterials and autologous implants." Bangladesh Journal of Otorhinolaryngology 19, no. 1 (2013): 29–35. http://dx.doi.org/10.3329/bjo.v19i1.12619.

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Objective: To determine amongst biomaterials (Teflon and Silicon) and autologous materials (autologous incus and cartilage), the one which give the best results of ossiculoplasty, in terms of increase in hearing sensitivity including cost effectiveness. Methods: Study was conducted in Eras Lucknow Medical College & Hospital, Lucknow, India. Randomized prospective crossover study with eighteen months follow up. 80 patients of Chronic Suppurative Otitis Media (CSOM) were randomly assigned for ossiculoplasty using biomaterials (Teflon and silicon) and autologous materials (bone and cartilage

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Chou, Da-Tren, Daeho Hong, Sinan Oksuz, et al. "Corrosion and bone healing of Mg-Y-Zn-Zr-Ca alloy implants: Comparative in vivo study in a non-immobilized rat femoral fracture model." Journal of Biomaterials Applications 33, no. 9 (2019): 1178–94. http://dx.doi.org/10.1177/0885328219825568.

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Biodegradable magnesium (Mg) alloys exhibit improved mechanical properties compared to degradable polymers while degrading in vivo circumventing the complications of permanent metals, obviating the need for surgical removal. This study investigated the safety and efficacy of Mg-Y-Zn-Zr-Ca (WZ42) alloy compared to non-degradable Ti6Al4V over a 14-week follow-up implanted as pins to fix a full osteotomy in rat femurs and as wires wrapped around the outside of the femurs as a cerclage. We used a fully load bearing model allowing implants to intentionally experience realistic loads without immobil

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Iviglia, Giorgio, Saeid Kargozar, and Francesco Baino. "Biomaterials, Current Strategies, and Novel Nano-Technological Approaches for Periodontal Regeneration." Journal of Functional Biomaterials 10, no. 1 (2019): 3. http://dx.doi.org/10.3390/jfb10010003.

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Periodontal diseases involve injuries to the supporting structures of the tooth and, if left untreated, can lead to the loss of the tooth. Regenerative periodontal therapies aim, ideally, at healing all the damaged periodontal tissues and represent a significant clinical and societal challenge for the current ageing population. This review provides a picture of the currently-used biomaterials for periodontal regeneration, including natural and synthetic polymers, bioceramics (e.g., calcium phosphates and bioactive glasses), and composites. Bioactive materials aim at promoting the regeneration

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Jia, Wei-Tao, Qiang Fu, Wen-Hai Huang, Chang-Qing Zhang, and Mohamed N. Rahaman. "Comparison of Borate Bioactive Glass and Calcium Sulfate as Implants for the Local Delivery of Teicoplanin in the Treatment of Methicillin-Resistant Staphylococcus aureus-Induced Osteomyelitis in a Rabbit Model." Antimicrobial Agents and Chemotherapy 59, no. 12 (2015): 7571–80. http://dx.doi.org/10.1128/aac.00196-15.

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ABSTRACTThere is growing interest in biomaterials that can cure bone infection and also regenerate bone. In this study, two groups of implants composed of 10% (wt/wt) teicoplanin (TEC)-loaded borate bioactive glass (designated TBG) or calcium sulfate (TCS) were created and evaluated for their ability to release TECin vitroand to cure methicillin-resistantStaphylococcus aureus(MRSA)-induced osteomyelitis in a rabbit model. When immersed in phosphate-buffered saline (PBS), both groups of implants provided a sustained release of TEC at a therapeutic level for up to 3 to 4 weeks while they were gr

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Schupbach, Peter, Roland Glauser, and Sebastian Bauer. "Al2O3 Particles on Titanium Dental Implant Systems following Sandblasting and Acid-Etching Process." International Journal of Biomaterials 2019 (June 2, 2019): 1–11. http://dx.doi.org/10.1155/2019/6318429.

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Dental implants with moderately rough surfaces show enhanced osseointegration and faster bone healing compared with machined surfaces. The sandblasting and acid-etching (SA) process is one technique to create moderately rough dental implant surfaces. The purpose of this study was to analyse different commercially available implant systems with a SA-modified surface and to explore the widespread notion that they have similar surface properties regarding morphology and cleanliness. SA-modified surfaces of nine implant systems manufactured by Alpha-Bio Tec Ltd, Camlog Biotechnologies AG, Dentsply

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Pavlov, O. D., V. V. Pastukh, and M. Yu Karpinsky. "The problem of using composite biodegradable implants for the treatment of bone fractures (literature review)." TRAUMA 22, no. 2 (2021): 5–16. http://dx.doi.org/10.22141/1608-1706.2.22.2021.231952.

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Diseases and injuries of the musculoskeletal system rank second among the causes of injuries and third among the diseases that lead to disability of the adult population. Orthopedic implants have a special place in both clinical practice and the biomedical industry. The implants capable of biodegrading in the case of their implantation into the human body are of the greatest interest. The concept of biodegra-dable implants appeared through the formation and development of the use of suture materials that are absorbed in the body. Subsequently, this type of material began to be used in the trea

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Raddatz, Lukas, Marline Kirsch, Dominik Geier, et al. "Comparison of different three dimensional-printed resorbable materials: In vitro biocompatibility, In vitro degradation rate, and cell differentiation support." Journal of Biomaterials Applications 33, no. 2 (2018): 281–94. http://dx.doi.org/10.1177/0885328218787219.

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Biodegradable materials play a crucial role in both material and medical sciences and are frequently used as a primary commodity for implants generation. Due to their material inherent properties, they are supposed to be entirely resorbed by the patients' body after fulfilling their task as a scaffold. This makes a second intervention (e.g. for implant removal) redundant and significantly enhances a patient’s post-operative life quality. At the moment, materials for resorbable and biodegradable implants (e.g. polylactic acid or poly-caprolactone polymers) are still intensively studied. They ar

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Băilă, Diana Irinel. "Researches Concerning the Phenomena at the Interface for the Sintered Compacts of Titan-Hydroxyapatite." Advanced Materials Research 856 (December 2013): 164–68. http://dx.doi.org/10.4028/www.scientific.net/amr.856.164.

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The behaviour of metallic powders is very important for manufacturing parts and for realize the prototypes. Manufacturing of the orthopaedic implants by selective laser sintering process can be used in medicine. The powders necessary for SLS process are biomaterials who must assure a good osteointegration of endobone implants like the Ti powder (Ti-6Al-4V) and the hydroxyapatite powder. The conditioned powders is a very important process and is necessary in SLS to obtain medical prothesis and influence the final properties of prothesis. Materials must present a gradient for porosity and one fo

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Talpos, Serban, Tareq Hajaj, Costin Timofte, et al. "Implant Surgery Using Bio-compatible Guides." Materiale Plastice 55, no. 1 (2018): 38–41. http://dx.doi.org/10.37358/mp.18.1.4959.

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Implants and biomaterials used in hard and soft oral tissue augmentation are very complex, but predictable to use nowadays, as the technological advances haven�t skipped this field of medicine. Cases that were impossible to treat with implant retained fixed prosthesis some years ago, have become the daily practice of oral surgeons and dentists around the world. The new user-friendly products, together with simplified protocols, increased the practitioners� predictability and success rate, thus the biomaterial industry took a huge leap forward. As the biomaterial industry keeps developing conti

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Zhukova, P. A., F. S. Senatov, M. Yu Zadorozhnyy, N. S. Chmelyuk, and V. A. Zaharova. "Polymer Composite Materials Based on Polylactide with a Shape Memory Effect for “Self-Fitting” Bone Implants." Polymers 13, no. 14 (2021): 2367. http://dx.doi.org/10.3390/polym13142367.

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The development of adaptive medical structures is one of the promising areas of bioengineering. Polymer composite materials based on polylactide (PLA) are interesting not only for their properties, such as biocompatibility, mechanical properties, biodegradation, and convenience of use, but also for demonstrating shape memory effect (SME). In this study, reducing the activation initiation temperature and the SME activation energy was achieved by forming a composite based on PLA containing 10% poly (ε-caprolactone) (PCL). The effect of the plasticizer on the structure, mechanical properties, and

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Heimann, Robert B. "Silicon Nitride, a Close to Ideal Ceramic Material for Medical Application." Ceramics 4, no. 2 (2021): 208–23. http://dx.doi.org/10.3390/ceramics4020016.

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This topical review describes the salient results of recent research on silicon nitride, a ceramic material with unique properties. The outcome of this ongoing research strongly encourages the use of monolithic silicon nitride and coatings as contemporary and future biomaterial for a variety of medical applications. Crystallographic structure, the synthesis and processing of monolithic structures and coatings, as well as examples of their medical applications that relate to spinal, orthopedic and dental implants, bone grafts and scaffolds, platforms for intelligent synthetic neural circuits, a

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Teske, Michael, Katharina Wulf, Joschka Fink, et al. "Controlled biodegradation of metallic biomaterials by plasma polymer coatings using hexamethyldisiloxane and allylamine monomers." Current Directions in Biomedical Engineering 5, no. 1 (2019): 315–17. http://dx.doi.org/10.1515/cdbme-2019-0079.

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AbstractPlasma enhanced chemical vapor deposition is a promising process for the generation of tailor-made polymer coatings on medical devices in order to improve their implant/ host interaction. The ultra-thin coatings can fulfil a variety of purposes, depending on the monomers used, the process conditions and the location of the coated implants in the human body. In addition, even complex geometries can be coated easily and without the application of solvents. Particularly hydrophilic and hydrophobic plasma polymer coatings can improve biocompatibility, especially in blood contact. Furthermo

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Munir, G., G. Koller, L. Di Silvio, M. J. Edirisinghe, W. Bonfield, and J. Huang. "The pathway to intelligent implants: osteoblast response to nano silicon-doped hydroxyapatite patterning." Journal of The Royal Society Interface 8, no. 58 (2010): 678–88. http://dx.doi.org/10.1098/rsif.2010.0548.

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Bioactive hydroxyapatite (HA) with addition of silicon (Si) in the crystal structure (silicon-doped hydroxyapatite (SiHA)) has become a highly attractive alternative to conventional HA in bone replacement owing to the significant improvement in the in vivo bioactivity and osteoconductivity. Nanometre-scaled SiHA (nanoSiHA), which closely resembles the size of bone mineral, has been synthesized in this study. Thus, the silicon addition provides an extra chemical cue to stimulate and enhance bone formation for new generation coatings, and the next stage in metallic implantation design is to furt

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Özcan, Mutlu, Dachamir Hotza, Márcio Celso Fredel, Ariadne Cruz, and Claudia Angela Maziero Volpato. "Materials and Manufacturing Techniques for Polymeric and Ceramic Scaffolds Used in Implant Dentistry." Journal of Composites Science 5, no. 3 (2021): 78. http://dx.doi.org/10.3390/jcs5030078.

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Preventive and regenerative techniques have been suggested to minimize the aesthetic and functional effects caused by intraoral bone defects, enabling the installation of dental implants. Among them, porous three-dimensional structures (scaffolds) composed mainly of bioabsorbable ceramics, such as hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) stand out for reducing the use of autogenous, homogeneous, and xenogenous bone grafts and their unwanted effects. In order to stimulate bone formation, biodegradable polymers such as cellulose, collagen, glycosaminoglycans, polylactic acid (PLA)

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Subramani, Karthikeyan. "Titanium Surface Modification Techniques for Implant Fabrication – From Microscale to the Nanoscale." Journal of Biomimetics, Biomaterials and Tissue Engineering 5 (February 2010): 39–56. http://dx.doi.org/10.4028/www.scientific.net/jbbte.5.39.

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This manuscript reviews about titanium surface modification techniques for its application in orthopaedic and dental implants. There are a few limitations in the long term prognosis of orthopaedic and dental implants. Poor osseointegration with bone, periimplant infection leading to implant failure and short term longevity demanding revision surgery, are to mention a few. Micro- and nanoscale modification of titanium surface using physicochemical, morphological and biochemical approaches have resulted in higher bone to implant contact ratio and improved osseointegration. With recent advances i

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Singh, Devendra Kumar, and Rajesh Kumar Verma. "Contemporary Development on the Performance and Functionalization of Ultra High Molecular Weight Polyethylene (UHMWPE) for Biomedical Implants." Nano LIFE 11, no. 03 (2021): 2130009. http://dx.doi.org/10.1142/s1793984421300090.

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Polymers are widely used in biomedical implants due to their low cost, ability to shape easily in different ways, low friction and strong anti-corrosion properties. Numerous polymers such as polytetrafluoroethylene (PTFE), polyamide (PA), polymethylmethacrylate (PMMA), polyether ether ketone (PEEK), polyurethane (PU), Epoxy and ultra-high-molecular-weight polyethylene (UHMWPE) are used to develop modified biomaterials applications. Among these polymers, UHMWPE stands out as a polymer with superior customization properties to satisfy specific requirements of the human body. Investigations show

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Goga, Firuta, Edit Forizs, George Borodi, et al. "Behavior of Doped Hydroxyapatites During the Heat Treatment." Revista de Chimie 68, no. 12 (2018): 2907–13. http://dx.doi.org/10.37358/rc.17.12.6004.

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The goal of this investigation is related to the development of nanostructured biomaterials based on hydroxyapatite (HAP) and multi-doped hydroxyapatites (HAPs), with essential physiological elements, like Mg, Zn, Sr, and Si, for bone repair and regeneration. Nano hydroxyapatites pastes and powders were obtained by wet chemical method using innovative nanotechnology and advanced processing of biomaterials at various temperatures to control the crystallite size and crystallinity degree. The prepared HAPs were analysed by various physical and chemical methods, like SEM, SEM-EDX, AFM, XRD, TG and

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Sideris, Anders, Gordon Wallace, Matthew Lam, et al. "268 Smart polymer implants as an emerging technology for treating airway collapse in OSA: a proof of concept study." Sleep 44, Supplement_2 (2021): A107—A108. http://dx.doi.org/10.1093/sleep/zsab072.267.

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Abstract Introduction Implantable 3D printed ‘smart’ polymers are an emerging technology with potential applications in treating collapse in adult obstructive sleep apnea through mechanical airway manipulation. There is a paucity of devices that are commercially available or in research and development stage. Limited studies have investigated the use of implantable smart polymers in reversing the collapsibility of the pharyngeal airway by creating counter forces during sleep. This paper describes an application of implantable magnetic polymer technology in an in-vivo porcine model. Study Objec

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Bano, Shaher, Memoona Akhtar, Muhammad Yasir, et al. "Synthesis and Characterization of Silver–Strontium (Ag-Sr)-Doped Mesoporous Bioactive Glass Nanoparticles." Gels 7, no. 2 (2021): 34. http://dx.doi.org/10.3390/gels7020034.

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Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc., are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag)- and strontium (Sr)-doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ and Sr2+ were co-substituted in pure MBGNs to harvest the antiba

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Wattanutchariya, Wassanai, and Teerawat Sangkas. "Effect of forming condition on compressive strength of hydroxyapatite-bioactive glass compact rod." MATEC Web of Conferences 192 (2018): 01002. http://dx.doi.org/10.1051/matecconf/201819201002.

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With rising concerns regarding alloy implants, alternative biomaterials are currently studied, to avoid the adverse effects of metal on the human body such as irritation and inflammation. Hydroxyapatite (HA) and Bioactive glass (BG) are two bio-ceramics, which have been implemented in medical applications such as bone implants and fixation parts due to their biocompatibility and close resemblance to the mineralized phase of human bone. Furthermore, these materials can be synthesized from natural sources. In this study, M8 screws rod which are commonly implemented for bone fixation was selected

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Çetin Altındal, Damla, Eric N. James, David L. Kaplan, and Menemşe Gümüşderelioğlu. "Melatonin-induced osteogenesis with methanol-annealed silk materials." Journal of Bioactive and Compatible Polymers 34, no. 3 (2019): 291–305. http://dx.doi.org/10.1177/0883911519847489.

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Melatonin, a hormone produced in the pineal gland, has been investigated for bone repair, remodeling, osteoporosis, as well as osseointegration of the implants. In this study, different concentrations of melatonin (0–2000-µM) were embedded into silk films annealed by methanol or water. Then, their capacity to differentiate human mesenchymal stem cells into osteoblasts was investigated for bone tissue regeneration. While methanol-annealed silk films have ~55% crystallinity, room-temperature water-annealed silk films have ~30% crystallinity by depending upon their different β-sheet contents. Mel

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Gherasim, Oana, Gianina Popescu-Pelin, Paula Florian, et al. "Bioactive Ibuprofen-Loaded PLGA Coatings for Multifunctional Surface Modification of Medical Devices." Polymers 13, no. 9 (2021): 1413. http://dx.doi.org/10.3390/polym13091413.

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To modulate the biofunctionality of implantable medical devices commonly used in clinical practice, their surface modification with bioactive polymeric coatings is an attractive and successful emerging strategy. Biodegradable coatings based on poly(lactic acid-co-glycolic acid), PLGA, represent versatile and safe candidates for surface modification of implantable biomaterials and devices, providing additional tunable ability for topical delivery of desired therapeutic agents. In the present study, Ibuprofen-loaded PLGA coatings (PLGA/IBUP) were obtained by using the dip-coating and drop-castin

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