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Journal articles on the topic 'Biomechanics of the heart'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Sacks, Michael S., and Ajit P. Yoganathan. "Heart valve function: a biomechanical perspective." Philosophical Transactions of the Royal Society B: Biological Sciences 362, no. 1484 (2007): 1369–91. http://dx.doi.org/10.1098/rstb.2007.2122.

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Heart valves (HVs) are cardiac structures whose physiological function is to ensure directed blood flow through the heart over the cardiac cycle. While primarily passive structures that are driven by forces exerted by the surrounding blood and heart, this description does not adequately describe their elegant and complex biomechanical function. Moreover, they must replicate their cyclic function over an entire lifetime, with an estimated total functional demand of least 3×10 9 cycles. As in many physiological systems, one can approach HV biomechanics from a multi-length-scale approach, since m

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Sacks, Michael S., W. David Merryman, and David E. Schmidt. "On the biomechanics of heart valve function." Journal of Biomechanics 42, no. 12 (2009): 1804–24. http://dx.doi.org/10.1016/j.jbiomech.2009.05.015.

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Krasny, R., H. Kammermeier, and J. Köhler. "Biomechanics of valvular plane displacement of the heart." Basic Research in Cardiology 86, no. 6 (1991): 572–81. http://dx.doi.org/10.1007/bf02190708.

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Kodigepalli, Karthik M., Kaitlyn Thatcher, Toni West, et al. "Biology and Biomechanics of the Heart Valve Extracellular Matrix." Journal of Cardiovascular Development and Disease 7, no. 4 (2020): 57. http://dx.doi.org/10.3390/jcdd7040057.

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Heart valves are dynamic structures that, in the average human, open and close over 100,000 times per day, and 3 × 109 times per lifetime to maintain unidirectional blood flow. Efficient, coordinated movement of the valve structures during the cardiac cycle is mediated by the intricate and sophisticated network of extracellular matrix (ECM) components that provide the necessary biomechanical properties to meet these mechanical demands. Organized in layers that accommodate passive functional movements of the valve leaflets, heart valve ECM is synthesized during embryonic development, and remode

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Liu, Wenqiang, and Zhijie Wang. "Current Understanding of the Biomechanics of Ventricular Tissues in Heart Failure." Bioengineering 7, no. 1 (2019): 2. http://dx.doi.org/10.3390/bioengineering7010002.

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Heart failure is the leading cause of death worldwide, and the most common cause of heart failure is ventricular dysfunction. It is well known that the ventricles are anisotropic and viscoelastic tissues and their mechanical properties change in diseased states. The tissue mechanical behavior is an important determinant of the function of ventricles. The aim of this paper is to review the current understanding of the biomechanics of ventricular tissues as well as the clinical significance. We present the common methods of the mechanical measurement of ventricles, the known ventricular mechanic

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Kovacheva, Ekaterina, Lukas Baron, Steffen Schuler, Tobias Gerach, Olaf Dössel, and Axel Loewe. "Optimization Framework to Identify Constitutive Law Parameters of the Human Heart." Current Directions in Biomedical Engineering 6, no. 3 (2020): 95–98. http://dx.doi.org/10.1515/cdbme-2020-3025.

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AbstractOver the last decades, computational models have been applied in in-silico simulations of the heart biomechanics. These models depend on input parameters. In particular, four parameters are needed for the constitutive law of Guccione et al., a model describing the stress-strain relation of the heart tissue. In the literature, we could find a wide range of values for these parameters. In this work, we propose an optimization framework which identifies the parameters of a constitutive law. This framework is based on experimental measurements conducted by Klotz et al.. They provide an end

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Shi, Xiaodan, Yue Liu, Katherine M. Copeland, et al. "Epicardial prestrained confinement and residual stresses: a newly observed heart ventricle confinement interface." Journal of The Royal Society Interface 16, no. 152 (2019): 20190028. http://dx.doi.org/10.1098/rsif.2019.0028.

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The heart epicardial layer, with elastin as the dominant component, has not been well investigated, specifically on how it contributes to ventricular biomechanics. In this study, we revealed and quantitatively assessed the overall status of prestraining and residual stresses exerted by the epicardial layer on the heart left ventricle (LV). During porcine heart wall dissection, we discovered that bi-layered LV surface strips, consisting of an epicardial layer and cardiac muscle, always curled towards the epicardial side due to epicardial residual stresses. We hence developed a curling angle cha

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KAJIYA, MASAHITO, OSAMU HIRAMATSU, TOYOTAKA YADA, et al. "PHYSIOMIC APPROACH TO BIOMECHANICS OF CORONARY MICROCIRCULATION." Journal of Mechanics in Medicine and Biology 05, no. 01 (2005): 1–9. http://dx.doi.org/10.1142/s021951940500128x.

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The recently proposed Physiome is considered as a powerful successor to the Genome. The definition of Physiome is the quantitative description of the physiological dynamics or functions of the intact organism. The physiome includes integration of knowledge through functional modules of hierarchical system elements of biological systems, and modeling. Biomechanics will offer potent tools to promote the Physiome. By using modern microvisualization technology with physiomic model, this manuscript introduces our physiomic approach to coronary microcirculation which supplies oxygen and nutrients to

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Trembach, Nikita, and Igor Zabolotskikh. "Recruitment Maneuver in Elderly Patients with Different Peripheral Chemoreflex Sensitivity during Major Abdominal Surgery." BioMed Research International 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/2974852.

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The goal of the study was to evaluate the effect of a recruitment maneuver on respiratory biomechanics, oxygenation, and hemodynamics in patients suffering from chronic heart failure with different peripheral chemoreflex sensitivity. The study was conducted in 115 elderly patients which underwent major abdominal surgery under general/epidural surgery. Peripheral chemoreflex sensitivity (PCS) was evaluated with breath-holding duration (BHD) during breath-holding test. All patients were divided into two groups: group H had a high PCS (BHD = 38 seconds or less,n=49); Group M had a middle PCS (BHD

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Hunter, P., and M. Tawhai. "Biomechanics of the heart and lungs: Challenges in multi-scale modelling." Journal of Biomechanics 39 (January 2006): S3. http://dx.doi.org/10.1016/s0021-9290(06)82876-9.

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11

Denfeld, Quin E., James O. Mudd, Jill M. Gelow, Christopher Chien, Shirin O. Hiatt, and Christopher S. Lee. "Physical and Psychological Symptom Biomechanics in Moderate to Advanced Heart Failure." Journal of Cardiovascular Nursing 30, no. 4 (2015): 346–50. http://dx.doi.org/10.1097/jcn.0000000000000171.

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Bia, Daniel, Yanina Zócalo, Sandra Wray, and Edmundo I. Cabrera-Fischer. "Comparative in Vivo Analysis of the Role of the Adventitia and the Endothelium on Arterial Mechanical Function: Relevance for Aortic Counterpulsation." International Journal of Artificial Organs 40, no. 6 (2017): 286–93. http://dx.doi.org/10.5301/ijao.5000585.

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Purpose The comparative effect of the intimal and adventitial layers on arterial biomechanics control, in basal and altered conditions, remains to be elucidated. This study aimed ( 1 ) to characterize the arterial conduit (CF) and buffering (distensibility) function of the iliac arteries in in vivo animals, in which the intimal and adventitial layers were removed; ( 2 ) to determine the effects of intra-aortic ballon pumping (IABP) on simultaneously de-adventitialized (DA) and de-endothelialized (DE) iliac arteries before and after induced heart failure. Methods Pressure and diameter signals w

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Kang, Yaw Hong, Ha Hai Vu, Cheung Hwa Hsu, Kai Wen Yang, and Wu Chiao Shih. "A Newly Developed Polyurethane Prosthetic Heart Valve." Applied Mechanics and Materials 479-480 (December 2013): 463–67. http://dx.doi.org/10.4028/www.scientific.net/amm.479-480.463.

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Polyurethane prosthetic heart valve tried to imitate the geometry of native valve that might perhaps show better performance which is close to natural valve. However, the geometry of natural valve is very complex and there are variety of parameters can affect performances of the valves. This study has simplified the geometry of natural valve so that there are only four parameters needs to be considered. The four parameters include the fundamental curve, the free edge angle, the valve height, and the leaflet thickness. The study investigated the influence of these four parameters on biomechanic

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Saberi, Ali Asqar, Merdad Fathi, and Keyvan Hejazi. "Comparing the Effect of Eight Weeks of Resistance and Endurance Trainings on Physiological and Functional Factors and Record of Elite Runners." Journal of Sport Biomechanics 6, no. 1 (2020): 32–43. http://dx.doi.org/10.32598/biomechanics.6.1.5.

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Objective: The 3000-meter run is one of the most popular events among endurance and semi-endurance track runnings. Due to its special conditions, aerobic and anaerobic energy production systems can be used at the same time. The aim of the present study was to compare the effect of eight weeks of resistance and endurance trainings on physiological and functional factors and record of elite runners. Methods: In this quasi-experimental study, 22 male elite runners were randomly assigned into the two groups of resistance (n=11) and endurance (n=11) trainings. The resistance and endurance trainings

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15

Taber, Larry A. "Biomechanics of Growth, Remodeling, and Morphogenesis." Applied Mechanics Reviews 48, no. 8 (1995): 487–545. http://dx.doi.org/10.1115/1.3005109.

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This review deals with biomechanical aspects of growth (mass change), remodeling (property change), and morphogenesis (shape change) in living systems. The emphasis is on theoretical models, but relevant experimental results also are discussed. As an aid to the reader, the fundamental biological terms and concepts are defined for the general problem and for each specific topic. At the outset, the processes involved in growth, remodeling, and morphogenesis are described and placed within the context of the evolution of species. Next, some of the analytical methods used in biomechanical models f

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May-Newman, Karen, Luz Enriquez-Almaguer, Phanthiwa Posuwattanakul, and Walter Dembitsky. "Biomechanics of the Aortic Valve in the Continuous Flow VAD-Assisted Heart." ASAIO Journal 56, no. 4 (2010): 301–8. http://dx.doi.org/10.1097/mat.0b013e3181e321da.

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Li, Richard L., Jonathan Russ, Costas Paschalides, et al. "Mechanical considerations for polymeric heart valve development: Biomechanics, materials, design and manufacturing." Biomaterials 225 (December 2019): 119493. http://dx.doi.org/10.1016/j.biomaterials.2019.119493.

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18

Weinberg, Eli J., Danial Shahmirzadi, and Mohammad Reza Kaazempur Mofrad. "On the multiscale modeling of heart valve biomechanics in health and disease." Biomechanics and Modeling in Mechanobiology 9, no. 4 (2010): 373–87. http://dx.doi.org/10.1007/s10237-009-0181-2.

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Lopatiev, A. O., A. P. Vlasov, and A. P. Demichkovskyi. "Peculiarities of Simulation of Biomechanical and Biological Systems." Teorìâ ta Metodika Fìzičnogo Vihovannâ 17, no. 2 (2017): 79–85. http://dx.doi.org/10.17309/tmfv.2017.2.1192.

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The objective is to combine the methods and principles of biomechanics and continuum mechanics in order to pose and solve problems that have practical application in extreme conditions. Materials & methods: the movement of blood through large vessels was studied on the basis of the Euler and Navier-Stokes equations. Analysis of the cardiovascular system was used for the examination of the functional state of the athlete. The initial experimentally measured heart rate (HR) was determined by the Polar RC800 cardiac monitor. The resulting time series is analyzed using the software package Kub

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Imbrie-Moore, Annabel M., Matthew H. Park, Michael J. Paulsen, et al. "Biomimetic six-axis robots replicate human cardiac papillary muscle motion: pioneering the next generation of biomechanical heart simulator technology." Journal of The Royal Society Interface 17, no. 173 (2020): 20200614. http://dx.doi.org/10.1098/rsif.2020.0614.

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Papillary muscles serve as attachment points for chordae tendineae which anchor and position mitral valve leaflets for proper coaptation. As the ventricle contracts, the papillary muscles translate and rotate, impacting chordae and leaflet kinematics; this motion can be significantly affected in a diseased heart. In ex vivo heart simulation, an explanted valve is subjected to physiologic conditions and can be adapted to mimic a disease state, thus providing a valuable tool to quantitatively analyse biomechanics and optimize surgical valve repair. However, without the inclusion of papillary mus

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Carrier, Bryson, Andrew Creer, Lauren R. Williams, et al. "Validation of Garmin Fenix 3 HR Fitness Tracker Biomechanics and Metabolics (VO2max)." Journal for the Measurement of Physical Behaviour 3, no. 4 (2020): 331–37. http://dx.doi.org/10.1123/jmpb.2019-0066.

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The purpose of this study was to determine the validity of the Garmin fēnix® 3 HR fitness tracker. Methods: A total of 34 healthy recreational runners participated in biomechanical or metabolic testing. Biomechanics participants completed three running conditions (flat, incline, and decline) at a self-selected running pace, on an instrumented treadmill while running biomechanics were tracked using a motion capture system. Variables extracted were compared with data collected by the Garmin fēnix 3 HR (worn on the wrist) that was paired with a chest heart rate monitor and a Garmin Foot Pod (worn

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Phillips, Winfred M. "The Artificial Heart: History and Current Status." Journal of Biomechanical Engineering 115, no. 4B (1993): 555–57. http://dx.doi.org/10.1115/1.2895539.

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Twenty-years ago groups from California to Massachusetts were actively involved in the development of an artificial heart. From biomaterials development to biomedical power sources, the supporting industry and spin-off benefit was broad indeed. Young people were seeking careers in biomedical engineering and science. The National Institutes of Health was supporting artificial heart research at $10 to $12 million dollar levels. Groups at Andros, Inc. (now Baxter Novacor) and Stanford, Thoratec, Penn State and the Hershey Medical Center, Cleveland Clinic and the Division of Artificial Organs, the

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Sandbakk, Øyvind, Matt Spencer, Gertjan Ettema, Silvana Bucher Sandbakk, Knut Skovereng, and Boye Welde. "The Physiology and Biomechanics of Upper-Body Repeated Sprints in Ice Sledge Hockey." International Journal of Sports Physiology and Performance 9, no. 1 (2014): 77–84. http://dx.doi.org/10.1123/ijspp.2012-0355.

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Purpose:To investigate performance and the associated physiological and biomechanical responses during upper-body repeated-sprint work.Methods:Twelve male ice sledge hockey players from the Norwegian national team performed eight 30-m sprints with start every 30 s and an active recovery between sprints. Time was captured every 10 m by photocells, cycle length and rate were determined by video analyses, and heart rate and blood lactate concentration were measured by conventional methods.Results:The percentage sprint decrement was 7% over the 8 trials, with significant reductions in performance

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Germanova, O. A., V. A. Germanov, Yu V. Shchukin, A. V. Germanov, and M. V. Piskunov. "Extrasystoles: adverse effects of the first postextrasystolic contraction." Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH), no. 6 (March 31, 2021): 89–97. http://dx.doi.org/10.20340/vmi-rvz.2020.6.11.

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Aim. To determine the changes of parameters of heart biomechanics and kinetics of arteries, to reveal the adverse events of first post-extrasystolic contraction.Materials and methods. In our investigation we included 286 patients. We excluded all the main traditional risk factors of the atherosclerosis. All the patients were branched into two main groups in accordance to the quantity of extrasystoles per 24 hours: I group – less than 3000, II group – more than 3000 extrasystoles per 24 hours. We took the data about complaints, anamnesis, made laboratory and instrumental investigations to revea

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Paulsen, Michael J., Annabel M. Imbrie-Moore, Michael Baiocchi, et al. "Comprehensive Ex Vivo Comparison of 5 Clinically Used Conduit Configurations for Valve-Sparing Aortic Root Replacement Using a 3-Dimensional–Printed Heart Simulator." Circulation 142, no. 14 (2020): 1361–73. http://dx.doi.org/10.1161/circulationaha.120.046612.

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Background: Many graft configurations are clinically used for valve-sparing aortic root replacement, some specifically focused on recapitulating neosinus geometry. However, the specific impact of such neosinuses on valvular and root biomechanics and the potential influence on long-term durability are unknown. Methods: Using a custom 3-dimenstional–printed heart simulator with porcine aortic roots (n=5), the anticommissural plication, Stanford modification, straight graft (SG), Uni-Graft, and Valsalva graft configurations were tested in series using an incomplete counterbalanced measures design

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van der Valk, Dewy, Casper van der Ven, Mark Blaser, et al. "Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics." Nanomaterials 8, no. 5 (2018): 296. http://dx.doi.org/10.3390/nano8050296.

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Fatima, Maryam, Ayesha Sohail, Khush Bakhat Akram, et al. "BIOMECHANICS OF SUPERPARAMAGNETIC NANOPARTICLES FOR LASER HYPERTHERMIA." Biomedical Engineering: Applications, Basis and Communications 32, no. 01 (2020): 2050007. http://dx.doi.org/10.4015/s1016237220500076.

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Nanoparticle hyperthermia treatment is progressing with the passage of time, and with the development in the field of hybrid nanoparticles synthesis. The transient heat transfer in magnetite–graphene nanocomposite in three dimension under conduction is studied during this research. The proposed model is simulated in finite element solver framework. Novel hybrid nanoparticles were synthesized. Their chemical properties and their heat transfer properties were examined. By mathematical modeling results, the effective hybrid nanoparticle is chosen that can be used as a drug in hyperthermia process

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Alhadrami, Hani A., Raza ur Rehman Syed, Alap Ali Zahid, Rashid Ahmed, Shajia Hasan, and Anwarul Hasan. "Structure and Rheological Properties of Bovine Aortic Heart Valve and Pericardium Tissue: Implications in Bioprosthetic and Tissue-Engineered Heart Valves." Journal of Healthcare Engineering 2019 (December 28, 2019): 1–9. http://dx.doi.org/10.1155/2019/3290370.

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Heart valve (HV) diseases are among the leading causes of cardiac failure and deaths. Of the various HV diseases, damaged HV leaflets are among the primary culprits. In many cases, impaired HV restoration is not always possible, and the replacement of valves becomes necessary. Bioprosthetic HVs have been used for the replacement of the diseased valves, which is obtained from the sources of bovine and porcine origin, while tissue-engineered heart valves (TEHV) have emerged as a promising future solution. The bioprosthetic valves are prone to become calcified, and thus they last for only ten to

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Douglas, J. L., M. Price, and D. M. Peters. "A systematic review of physical fitness, physiological demands and biomechanical performance in equestrian athletes." Comparative Exercise Physiology 8, no. 1 (2012): 53–62. http://dx.doi.org/10.3920/cep12003.

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This article presents a systematic review of the literature investigating physical fitness, physiological demands and biomechanical performance in equestrian athletes. Three databases (SportsDiscus, CAB abstracts and PubMed) were searched to identify the literature. The main search term of ‘horse-riding’ was combined with eleven specific keywords (‘fitness’, ‘physiology’, ‘biomechanics’, ‘equestrian’, ‘athlete’, ‘co-ordination’, ‘heart rate’, ‘oxygen consumption’ ‘kinematic’ ‘EMG’ and ‘skill’). Exclusion criteria were: conference proceedings, abstracts, theses, and non-peer reviewed articles.

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Deng, James Makol Madut, and Oluwole Daniel Makinde. "Biomechanics of Surface Runoff and Soil Water Percolation." Defect and Diffusion Forum 401 (May 2020): 36–46. http://dx.doi.org/10.4028/www.scientific.net/ddf.401.36.

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In this study, the complex interaction of surface runoff with the biomechanics of soil water transport and heat transfer rate is theoretically investigated using a mathematical model that relies on the two phase flows of an incompressible Newtonian fluid (stormwater) within the soil (porous medium) and on the soil surface (runoff). The flow and heat transfer characteristics within the soil are determined numerically based on Darcy-Brinkman-Forchheimer model for porous medium coupled with the appropriate energy equation while analytical approach is employed to tackle the model for interacting s

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Glushkov, A. A., R. G. Salakhov, A. D. Yunusova, and D. A. Lebedev. "Possibility of osteopathic correction in the complex therapy of patients after sternotomy performed in connection with the surgical treatment of acquired heart defects." Russian Osteopathic Journal, no. 1-2 (June 6, 2020): 122–30. http://dx.doi.org/10.32885/2220-0975-2020-1-2-122-130.

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Introduction. Acquired heart defect affect people of different ages and lead to permanent disability, so this is important social problem. The single effective way to treat acquired heart defect, which can significantly increase the life expectancy of patients, is surgical correction aimed at eliminating severe hemodynamic disorders. Sternotomy mediates subsequent changes in the biomechanics of respiration, contributes to the appearance of pain in the thoracic region of the spinal column and ribs. In this regard, the possibility of osteopathic diagnosis and correction of such patients in the p

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Ardestani, Marzieh M., Christopher E. Henderson, Gordhan Mahtani, Mark Connolly, and T. George Hornby. "Locomotor Kinematics and Kinetics Following High-Intensity Stepping Training in Variable Contexts Poststroke." Neurorehabilitation and Neural Repair 34, no. 7 (2020): 652–60. http://dx.doi.org/10.1177/1545968320929675.

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Background and Purpose. Previous studies suggest that individuals poststroke can achieve substantial gains in walking function following high-intensity locomotor training (LT). Recent findings also indicate practice of variable stepping tasks targeting locomotor deficits can mitigate selected impairments underlying reduced walking speeds. The goal of this study was to investigate alterations in locomotor biomechanics following 3 different LT paradigms. Methods. This secondary analysis of a randomized trial recruited individuals 18 to 85 years old and >6 months poststroke. We compared change

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Wilczek, P. "Heart valve bioprothesis; effect of different acellularizations methods on the biomechanical and morphological properties of porcine aortic and pulmonary valve." Bulletin of the Polish Academy of Sciences: Technical Sciences 58, no. 2 (2010): 337–42. http://dx.doi.org/10.2478/v10175-010-0032-4.

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Heart valve bioprothesis; effect of different acellularizations methods on the biomechanical and morphological properties of porcine aortic and pulmonary valveTissue engineering is a promising tool for the creation of a new type of the heart valve bioprothesis. The biological scaffold composed of decellularized tissue has been successfully used for the constructions of the valve prosthesis. An analysis of the efficiency of the valve leaflet acellularization methods and the influence of those methods on the morphology and the biomechanical properties of the ECM (extra cellular matrix) was perfo

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Marom, Gil, Romina Plitman Mayo, Nadav Again, and Ehud Raanani. "Numerical Biomechanics Models of the Interaction Between a Novel Transcatheter Mitral Valve Device and the Subvalvular Apparatus." Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery 16, no. 4 (2021): 327–33. http://dx.doi.org/10.1177/1556984521999362.

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Objective Mitral valve regurgitation (MR) is a common valvular heart disease where improper closing causes leakage. Currently, no transcatheter mitral valve device is commercially available. Raanani (co-author) and colleagues have previously proposed a unique rotational implantation, ensuring anchoring by metallic arms that pull the chordae tendineae. This technique is now being implemented in a novel device design. The aim of this study is to quantify the rotational implantation effect on the mitral annulus kinematics and on the stresses in the chordae and papillary muscles. Methods Finite el

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Germanovich, Andrew. "Multi-Modal Treatment Approach to Painful Rib Syndrome: Case Series and Review of the Literature." March 2016 3;19, no. 3;3 (2016): E465—E471. http://dx.doi.org/10.36076/ppj/2019.19.e465.

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Background: Mechanical chest wall pain is a common presenting complaint in the primary care office, emergency room, and specialty clinic. Diagnostic testing is often expensive due to similar presenting symptoms that may involve the heart or lungs. Since the chest wall biomechanics are poorly understood by many clinicians, few effective treatments are offered to patients with rib-related acute pain, which may lead to chronic pain. Objective: This case series and literature review illustrates biomechanics involved in the pathogenesis of rib-related chest wall pain and suggests an effective multi

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Paulsen, Michael J., Patpilai Kasinpila, Annabel M. Imbrie-Moore, et al. "Modeling conduit choice for valve-sparing aortic root replacement on biomechanics with a 3-dimensional–printed heart simulator." Journal of Thoracic and Cardiovascular Surgery 158, no. 2 (2019): 392–403. http://dx.doi.org/10.1016/j.jtcvs.2018.10.145.

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Deshmukh, Mayura P., Tushar J. Palekar, and Mrudula V. Sangaonkar. "Effect of Backpack Load Influencing the Cardio-Respiratory Changes in Stair Climbing in Adolescents." International Journal of Health Sciences and Research 11, no. 6 (2021): 329–36. http://dx.doi.org/10.52403/ijhsr.20210649.

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Postural and physiological changes are the distinct changes occurring in the adolescence which contributes fitness level of a child. The biomechanics of these children are highly affected by load carriage while climbing stairs which results in increase in cardio respiratory responses. Evaluation of the cardio respiratory changes is necessary in curbing further damage. In the study we evaluated the effect of backpack load influencing the cardio respiratory measures in stair climbing adolescents. 100 adolescents subjects aged 13-16 yrs were selected for the study, with graded loading for three c

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Friedlander, Arthur H., and Lester J. Jones. "The Biology, Medical Management, and Podiatric Implications of Menopause." Journal of the American Podiatric Medical Association 92, no. 8 (2002): 437–43. http://dx.doi.org/10.7547/87507315-92-8-437.

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Approximately 36 million women in the United States are in the postmenopausal phase of life, creating unique challenges for the provision of compassionate, comprehensive podiatric medical treatment. Long-term estrogen deprivation arising from menopause in association with age-related factors disproportionately increases the risk of ischemic heart disease, osteoporosis, and concomitant podiatric complications. This article discusses the physiologic basis of menopause, hormone replacement therapy and its effects on osteoporosis, and other podiatric implications of menopause. Podiatric physicians

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Perrotin, Noé, Nicolas Gardan, Arnaud Lesprillier, et al. "Biomechanics of Trail Running Performance: Quantification of Spatio-Temporal Parameters by Using Low Cost Sensors in Ecological Conditions." Applied Sciences 11, no. 5 (2021): 2093. http://dx.doi.org/10.3390/app11052093.

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The recent popularity of trail running and the use of portable sensors capable of measuring many performance results have led to the growth of new fields in sports science experimentation. Trail running is a challenging sport; it usually involves running uphill, which is physically demanding and therefore requires adaptation to the running style. The main objectives of this study were initially to use three “low-cost” sensors. These low-cost sensors can be acquired by most sports practitioners or trainers. In the second step, measurements were taken in ecological conditions orderly to expose t

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Guldner, Norbert W., Peter Klapproth, Petra RJ Margaritoff, Ralf Noel, Hans H. Sievers, and Martin Grossherr. "Impact of Valves in a Biomechanical Heart Model Assisting Failing Hearts." Asian Cardiovascular and Thoracic Annals 17, no. 6 (2009): 592–97. http://dx.doi.org/10.1177/0218492309349066.

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Dodson, R. Blair, Paul J. Rozance, Carson C. Petrash, Kendall S. Hunter, and Virginia L. Ferguson. "Thoracic and abdominal aortas stiffen through unique extracellular matrix changes in intrauterine growth restricted fetal sheep." American Journal of Physiology-Heart and Circulatory Physiology 306, no. 3 (2014): H429—H437. http://dx.doi.org/10.1152/ajpheart.00472.2013.

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Intrauterine growth restriction (IUGR) is a fetal complication of pregnancy epidemiologically linked to cardiovascular disease in the newborn later in life. However, the mechanism is poorly understood with very little research on the vascular structure and function during development in healthy and IUGR neonates. Previously, we found vascular remodeling and increased stiffness in the carotid and umbilical arteries, but here we examine the remodeling and biomechanics in the larger vessels more proximal to the heart. To study this question, thoracic and abdominal aortas were collected from a she

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Lei, Yang, Yushun Xia, and Yunbing Wang. "The tropoelastin and lysyl oxidase treatments increased the content of insoluble elastin in bioprosthetic heart valves." Journal of Biomaterials Applications 33, no. 5 (2018): 637–46. http://dx.doi.org/10.1177/0885328218807077.

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Valvular heart diseases lead to over 300,000 heart valve replacements worldwide each year. Commercially available bioprosthetic heart valves (BHVs) are mostly made from porcine or bovine pericardiums which were crosslinked by glutaraldehyde (GLUT). However, valve failures can occur within 10 years due to progressive degradation and calcification. GLUT could crosslink collagen but it fails to stabilize elastin. In this current study, we developed a new BHVs preparation strategy named as “GLUT/TE/LOXL/EGCG” that utilizes exogenous tropoelastin (TE)/lysyl oxidase (LOXL) and epigallocatechin galla

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pietrabissa, riccardo, and vincenzo stefano luisi. "what is the role of biomechanics in cardiac surgery?" Cardiology in the Young 14, S3 (2004): 1–3. http://dx.doi.org/10.1017/s104795110400647x.

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cardiac surgery is a discipline aimed at restoring the best cardiac function of diseased hearts. it is often necessary to implant devices, and surgical tools are of great help in achieving faster and safer procedures. paediatric cardiac surgery is a more recent specialization of cardiac surgery. in paediatric cardiac surgery, the problem is usually related to congenital malformations, consisting in the main of anatomical abnormalities which produce, among other problems, poor oxygenation of the blood, high cardiac afterload, cardiac failure, hemodynamic problems during growth, and so on. the p

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Slaughter, M. S., and A. Cheng. "Left Ventricular and Vascular Biomechanics in Advanced Heart Failure Patients Supported by Continuous and Pulsatile Left Ventricular Assist Devices." Journal of Surgical Research 186, no. 2 (2014): 493. http://dx.doi.org/10.1016/j.jss.2013.11.017.

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Liu, Aiping, Xin Yin, Liang Shi, et al. "Biomechanics of the Chick Embryonic Heart Outflow Tract at HH18 Using 4D Optical Coherence Tomography Imaging and Computational Modeling." PLoS ONE 7, no. 7 (2012): e40869. http://dx.doi.org/10.1371/journal.pone.0040869.

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Ramspacher, Caroline, Emily Steed, Francesco Boselli, et al. "Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies." Cell Reports 11, no. 10 (2015): 1564–76. http://dx.doi.org/10.1016/j.celrep.2015.05.010.

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Wang, Xinrui, and Robert H. Fitts. "Effects of regular exercise on ventricular myocyte biomechanics and KATP channel function." American Journal of Physiology-Heart and Circulatory Physiology 315, no. 4 (2018): H885—H896. http://dx.doi.org/10.1152/ajpheart.00130.2018.

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Exercise training is known to protect the heart from ischemia and improve function during exercise by reducing cardiomyocyte action potential duration (APD) and increasing contractility. The cellular mechanisms involve β-adrenergic regulation and the ATP-sensitive K+ (KATP) channel, but how each alters function of the left ventricle and sex specificity is unknown. To address this, female and male Sprague-Dawley rats were randomly assigned to wheel-running (TRN) or sedentary (SED) groups. After 6–8 wk of training, myocytes were isolated from the left ventricle and field stimulated at 1, 2, and

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Sacks, Michael S., and Ajit P. Yoganathan. "Heart valve function: a biomechanical perspective." Philosophical Transactions of the Royal Society B: Biological Sciences 363, no. 1502 (2008): 2481. http://dx.doi.org/10.1098/rstb.2008.0062.

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Sanakoyeva, Viktoriia A., Maksim S. Rybachenko, Alena A. Pukhayeva, and Aleksandr G. Avtandilov. "Myocardial biomechanics, intracardiac hemodynamics and endothelial function in patients before and after various types of pacemakers implantation." CardioSomatics 10, no. 2 (2019): 56–63. http://dx.doi.org/10.26442/22217185.2019.2.190307.

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This review presents 31 sources from 1995 to 2019. Atrioventricular blockades (AVB) 2-3 degrees occupy a special place among the causes of death from cardiovascular disease. The above AVB lead to a significant slowing of the heart rate and predispose to the development and progression of heart failure (HF) and the occurrence of acute hypoxia of the brain and attacks Morgagni-Adams-Stokes. The main method of treatment of hemodynamically significant AB-conduction disorders is electrocardiostimulation (ES), which is the basic method of treatment. A single chamber pacemaker is the most often impla

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Blyth, Kevin G., Alessandro Bellofiore, Geeshath Jayasekera, et al. "Dobutamine stress MRI in pulmonary hypertension: relationships between stress pulmonary artery relative area change, RV performance, and 10-year survival." Pulmonary Circulation 7, no. 2 (2017): 465–75. http://dx.doi.org/10.1177/2045893217704838.

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In pulmonary hypertension (PH), right ventricular (RV) performance determines survival. Pulmonary artery (PA) stiffening is an important biomechanical event in PH and also predicts survival based on the PA relative area change (RAC) measured at rest using magnetic resonance imaging (MRI). In this exploratory study, we sought to generate novel hypotheses regarding the influence of stress RAC on PH prognosis and the interaction between PA stiffening, RV performance and survival. Fifteen PH patients underwent dobutamine stress-MRI (ds-MRI) and right heart catheterization. RACREST, RACSTRESS, and

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