Relevant bibliographies by topics / Bioorthogonal

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Bioorthogonal'

Author: Grafiati
Published: 4 June 2021
Last updated: 31 January 2023

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Journal articles on the topic "Bioorthogonal"

1

Kormos, Attila, Alexandra Egyed, Jasmine M. Olvany, et al. "A Bioorthogonal Double Fluorogenic Probe to Visualize Protein–DNA Interaction." Chemosensors 10, no. 1 (2022): 37. http://dx.doi.org/10.3390/chemosensors10010037.

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Two sets of bioorthogonally applicable, double fluorogenic probes, capable of sensing DNA–protein interactions, were prepared by installing an azide or tetrazine motif onto structurally fluorogenic, DNA sensitive frames. Installation of these bioorthogonal functions onto DNA intercalating dyes furnished these scaffolds with reactivity based fluorogenicity, rendering these probes double-fluorogenic, AND-type logic switches that require the simultaneous occurrence of a bioorthogonal reaction and interaction with DNA to trigger high intensity fluorescence. The probes were evaluated for double flu
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Xiao, Yu, Wenxuan Wang, Xiaohua Tian, et al. "A Versatile Surface Bioengineering Strategy Based on Mussel-Inspired and Bioclickable Peptide Mimic." Research 2020 (June 25, 2020): 1–12. http://dx.doi.org/10.34133/2020/7236946.

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In this work, we present a versatile surface engineering strategy by the combination of mussel adhesive peptide mimicking and bioorthogonal click chemistry. The main idea reflected in this work derived from a novel mussel-inspired peptide mimic with a bioclickable azide group (i.e., DOPA4-azide). Similar to the adhesion mechanism of the mussel foot protein (i.e., covalent/noncovalent comediated surface adhesion), the bioinspired and bioclickable peptide mimic DOPA4-azide enables stable binding on a broad range of materials, such as metallic, inorganic, and organic polymer substrates. In additi
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Hennessy, James. "Bioorthogonal catalysts." Nature Materials 14, no. 8 (2015): 750. http://dx.doi.org/10.1038/nmat4380.

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Chen, Xueqian, Yong Zhang, Qing Yuan, et al. "Bioorthogonal chemistry in metal clusters: a general strategy for the construction of multifunctional probes for bioimaging in living cells and in vivo." Journal of Materials Chemistry B 9, no. 33 (2021): 6614–22. http://dx.doi.org/10.1039/d1tb00836f.

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Franzini, Raphael M., and Titas Deb. "The Unique Bioorthogonal Chemistry of Isonitriles." Synlett 31, no. 10 (2020): 938–44. http://dx.doi.org/10.1055/s-0039-1690849.

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The isocyano group is the structurally most compact bioorthogonal group known. It reacts with tetrazines under physiological conditions and has great potential for widespread use in the biosciences. In this account, we highlight the unique properties of the isocyano group as a bioorthogonal functionality. Protecting group chemistry based on the reaction of isonitriles and tetrazines that allows releasing payloads is a particular focus of the article. We further discuss the atypical steric attractions that take place in the transition state of the reaction between isonitriles and tetrazines, wh
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Lin, Mingwei, Shanshan Zou, Xinxing Liao, et al. "Ruthenium(ii) complexes as bioorthogonal two-photon photosensitizers for tumour-specific photodynamic therapy against triple-negative breast cancer cells." Chemical Communications 57, no. 36 (2021): 4408–11. http://dx.doi.org/10.1039/d1cc00661d.

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We developed the first Ru(ii) complex-based bioorthogonal two-photon photosensitizers. Through bioorthogonal labelling, they realize effective tumour-specific photodynamic therapy against triple-negative breast cancer cells.
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Tu, Julian, Dennis Svatunek, Saba Parvez, et al. "Isonitrile-responsive and bioorthogonally removable tetrazine protecting groups." Chemical Science 11, no. 1 (2020): 169–79. http://dx.doi.org/10.1039/c9sc04649f.

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Tetrazylmethyl groups are reported here as bioorthogonal protecting groups that are readily removed by isonitriles, establishing a valuable addition to the dissociative bioorthogonal chemistry and synthetic methodology toolboxes.
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Chen, Zhaowei, Hongjun Li, Yijie Bian, et al. "Bioorthogonal catalytic patch." Nature Nanotechnology 16, no. 8 (2021): 933–41. http://dx.doi.org/10.1038/s41565-021-00910-7.

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Patterson, David M., and Jennifer A. Prescher. "Orthogonal bioorthogonal chemistries." Current Opinion in Chemical Biology 28 (October 2015): 141–49. http://dx.doi.org/10.1016/j.cbpa.2015.07.006.

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Tu, Julian, Minghao Xu, and Raphael M. Franzini. "Dissociative Bioorthogonal Reactions." ChemBioChem 20, no. 13 (2019): 1615–27. http://dx.doi.org/10.1002/cbic.201800810.

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Dissertations / Theses on the topic "Bioorthogonal"

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Jensen, Stephanie Meryl, and Stephanie Meryl Jensen. "A Bioorthogonal Approach to Chemical Virology." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/621769.

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Dengue virus (DENV) is a mosquito-transmitted flavivirus that threatens approximately half of the world's population. In this dissertation, the use of bioorthogonal chemistry as a tool for researching emerging viral diseases, including DENV is explored. To this end, a bioorthogonally-modified amino acid was successfully installed within the proteome of DENV, which was used for the pull down of a known virus-protein interaction. This technology is intended to be broadly used for the determination of any virus-host interaction, through the installment of a non-perturbing modification that 1) doe
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King, Mathias. "Development of new bioorthogonal ligation reactions." Thesis, Strasbourg, 2013. http://www.theses.fr/2013STRAF021.

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Le principal objectif de cette thèse a consisté au développement d’une méthode de screenning pour la découverte de nouvelles réactions de ligations bioorthogonales ainsi que son application sur une bibliothèque développée pour cette étude. Par conséquent, un système de screening a été conçu en trois étapes consistant au départ en une analyse HPLC, puis une évaluation basée sur la fluorescence de haute résolution et finalement un test de microscopie confocal in cellulo. Puis, nous avons standardisé toutes les analyses avec les réactions CuAAC et SpAAC. En outre, nous avons synthétisés 18 réacti
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Evans, Helen. "Bioorthogonal chemistry for pretargeted PET imaging." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/24542.

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Positron Emission Tomography (PET) is emerging as a powerful method for imaging cancer through the design and development of new radiotracers. Antibodies have promising properties as ligands for targeting cancer, as they have the advantage of displaying high affinity for their respective receptors. However, the use of antibodies as radiotracers is limited to the use of long-lived isotopes, as these large biomolecules additionally display slow blood circulation and clearance. The use of short-lived isotopes such as 18F or 68Ga, in combination with antibodies, would provide the ideal balance bet
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Thomas, Éric. "Stratégies de marquage chimiospécifique et bioorthogonale pour l’analyse métabolomique des rétinoïdes." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAF052.

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Ce travail est composé de trois projets. Le premier projet a pour objectif de découvrir de nouveaux métabolites de la vitamine A. Il a consisté en la synthèse d’un analogue du rétinaldéhyde, portant une fonction azoture et permettant de suivre son devenir in vivo. Le second projet a consisté en l’élaboration de la sonde ATPP permettant l’analyse de l’ensemble des métabolites aldéhydiques d’un échantillon. La sonde permet un gain de sensibilité en LS-MS². Une analyse de sa biodistribution a été faite, et montre que la sonde ATPP, après injection intrapéritonéale, est distribuée in vivo. Concern
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Jimenez, Rosales Angelica. "Methyltransferases as bioorthogonal labelling tools for proteins." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/methyltransferases-as-bioorthogonal-labelling-tools-for-proteins(27231f93-7cdd-4c2d-9f31-0adc3f38b147).html.

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Development of enzymatic labelling methods has been driven by the importance of studying molecular structures and interactions to comprehend cellular processes. Methyltransferases (MTases), which regulate genetic expression by transferring a methyl group from the cofactor S-adenosyl-L-methionine (SAM) to DNA, histones and various proteins, have been shown to accept SAM analogues with an alternative alkyl group on the sulfonium centre. These alkyl groups can be transferred to the substrate, and with a further reaction can be selectively functionalized. Thus, MTases together with SAM analogues h
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Guo, Zijian. "Developing unstrained alkenes and alkynes for bioorthogonal chemistry." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/289423.

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Bioorthogonal reactions, due to its excellent selectivity and time-efficiency, have emerged as a popular tool for protein and cell probing. Among all the bioorthogonal reactions, the inverse electron-demand Diels-Alder reaction (IEDDA) reaction has its advantage of bearing the fastest kinetics. Although the IEDDA reaction drew considerable attention in chemical biology in the last decade, challenges lie in finding the suitable dienophiles. Strained dienophiles, for example, trans-cyclooctene derivatives, can undergo ultrafast IEDDA reactions and therefore have been extensively developed. Unstr
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Tipping, William James. "Spectroscopically bioorthogonal Raman imaging approaches for intracellular visualisation." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/29512.

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Sensitive and specific visualisation of biomolecules in living models is highly challenging because of the complexity of cellular systems. Raman spectroscopy provides chemical contrast based upon molecular vibrations within a sample. It is therefore a powerful approach in biomedicine for disease diagnosis, owing to its potential to provide a spectroscopic fingerprint of biological species. However, Raman scattering is a weak process, and therefore novel approaches are required in order to improve the detection sensitivity for biomolecular imaging in living systems. Here, novel approaches for b
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Nguyen, Celina Tien, and Celina Tien Nguyen. "Using Bioorthogonal Chemistry for Investigating Dengue Virus Interactome." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/625109.

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A mosquito-borne virus endemic to the tropics and subtropics, dengue (DENV) is the most common arbovirus in the world. Among other obstacles, an incomplete understanding of specific host-virus protein-protein interactions (PPI) challenges the development of vaccines and antiviral therapies for DENV. Previous studies on DENV PPI depend on genetic modifications, which can be tedious and time-consuming to accomplish. Mixing the principles of chemical biology and virology, the work in this thesis aims to take advantage of chemical modifications on DENV to pull down DENV-host PPI. First, this thesi
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Li, Chenge. "Development of bioorthogonal fluorogenic reporters for biological imaging." Thesis, Paris Sciences et Lettres (ComUE), 2017. http://www.theses.fr/2017PSLEE044/document.

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L'étude de la dynamique des protéines est essentielle pour comprendre les processus biologiques. Notre laboratoire a développé une nouvelle classe de protéines fluorescentes semi-synthétiques, appelée Fluorescence-Activating and absorption-Shifting Tag (FAST). Cette thèse de doctorat présente le développement de nouveaux systèmes FAST avec diverses propriétés pour l'imagerie multiplexée. Nous avons développé une série de fluorogènes permettant de modifier la couleur de FAST de vert-jaune à orange et rouge. Au delà de l’application de l’imagerie multi-couleurs, ces fluorogènes permettant un éch
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Favre, Camille. "Novel bioorthogonal chemical reporters and fluorogenic probes for biomolecules imaging." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0079.

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L'imagerie de biomolécules, et plus particulièrement des glycanes, au sein d'organismes vivants, représente un incroyable challenge. Cependant, des progrès significatifs ont été réalisés ces dix dernières années grâce au développement de la stratégie du rapporteur chimique bioorthogonal. Cette technique implique, dans un premier temps, l'incorporation d'une fonctionnalité chimique non native (rapporteur) au sein de biomolécules complexes. Ce rapporteur peut ensuite réagir sélectivement avec une sonde moléculaire spécifique permettant ainsi la détection de la biomolécule ciblée. Afin d'imager c
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Books on the topic "Bioorthogonal"

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Vrabel, Milan, and Thomas Carell, eds. Cycloadditions in Bioorthogonal Chemistry. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29686-9.

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Algar, W. Russ, Philip E. Dawson, and Igor L. Medintz, eds. Chemoselective and Bioorthogonal Ligation Reactions. Wiley-VCH Verlag GmbH & Co. KGaA, 2017. http://dx.doi.org/10.1002/9783527683451.

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Vrabel, Milan, and Thomas Carell. Cycloadditions in Bioorthogonal Chemistry. Springer, 2018.

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Vrabel, Milan, and Thomas Carell. Cycloadditions in Bioorthogonal Chemistry. Springer London, Limited, 2016.

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Vrabel, Milan, and Thomas Carell. Cycloadditions in Bioorthogonal Chemistry. Springer, 2016.

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Dawson, Philip, Igor L. Medintz, and W. Russ Algar. Chemoselective and Bioorthogonal Ligation Reactions: Concepts and Applications. Wiley & Sons, Incorporated, John, 2017.

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Dawson, Philip, Igor L. Medintz, and W. Russ Algar. Chemoselective and Bioorthogonal Ligation Reactions: Concepts and Applications. Wiley & Sons, Incorporated, John, 2017.

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Dawson, Philip, Igor L. Medintz, and W. Russ Algar. Chemoselective and Bioorthogonal Ligation Reactions: Concepts and Applications. Wiley & Sons, Incorporated, John, 2017.

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Dawson, Philip, Igor L. Medintz, and W. Russ Algar. Chemoselective and Bioorthogonal Ligation Reactions: Concepts and Applications. Wiley & Sons, Limited, John, 2017.

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Dawson, Philip, W. R. Algar, and Igor L. Medintz. Chemoselective and Bioorthogonal Ligation Reactions: Concepts and Applications. Wiley & Sons, Incorporated, John, 2017.

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Book chapters on the topic "Bioorthogonal"

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Carell, T., M. Vrabel, M. Yang, et al. "M. Vrabel and T. Carell for Cycloadditions in Bioorthogonal Chemistry." In Cycloadditions in Bioorthogonal Chemistry. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29686-9_1.

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Carell, Thomas, and Milan Vrabel. "Bioorthogonal Chemistry—Introduction and Overview." In Cycloadditions in Bioorthogonal Chemistry. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29686-9_2.

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Yang, Maiyun, Yi Yang, and Peng R. Chen. "Transition-Metal-Catalyzed Bioorthogonal Cycloaddition Reactions." In Cycloadditions in Bioorthogonal Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-29686-9_3.

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Dommerholt, Jan, Floris P. J. T. Rutjes, and Floris L. van Delft. "Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides." In Cycloadditions in Bioorthogonal Chemistry. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29686-9_4.

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Herner, András, and Qing Lin. "Photo-Triggered Click Chemistry for Biological Applications." In Cycloadditions in Bioorthogonal Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-29686-9_5.

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Wu, Haoxing, and Neal K. Devaraj. "Inverse Electron-Demand Diels–Alder Bioorthogonal Reactions." In Cycloadditions in Bioorthogonal Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-29686-9_6.

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Kath-Schorr, Stephanie. "Cycloadditions for Studying Nucleic Acids." In Cycloadditions in Bioorthogonal Chemistry. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-29686-9_7.

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Gordon, Chelsea G., and Carolyn R. Bertozzi. "In VivoApplications of Bioorthogonal Chemistries." In Chemoselective and Bioorthogonal Ligation Reactions. Wiley-VCH Verlag GmbH & Co. KGaA, 2017. http://dx.doi.org/10.1002/9783527683451.ch14.

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Friscourt, Frédéric, and Geert-Jan Boons. "Bioorthogonal Reactions for Labeling Glycoconjugates." In Click Chemistry in Glycoscience. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118526996.ch8.

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Algar, W. Russ. "A Brief Introduction to Traditional Bioconjugate Chemistry." In Chemoselective and Bioorthogonal Ligation Reactions. Wiley-VCH Verlag GmbH & Co. KGaA, 2017. http://dx.doi.org/10.1002/9783527683451.ch1.

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Conference papers on the topic "Bioorthogonal"

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Min, Wei. "BIOORTHOGONAL CHEMICAL IMAGING FOR BIOMEDICINE." In 72nd International Symposium on Molecular Spectroscopy. University of Illinois at Urbana-Champaign, 2017. http://dx.doi.org/10.15278/isms.2017.ra04.

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Min, Wei. "Bioorthogonal Chemical Imaging for Biomedicine." In Biomedical Optics. OSA, 2014. http://dx.doi.org/10.1364/biomed.2014.bm2a.5.

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Arndt, Stefanie, Effi Bätzner, Ulrike Bruckner, Claudia Stubinitzky, and Hans-Achim Wagenknecht. "Usage of bioorthogonal methods in DNA modification." In XVIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2014. http://dx.doi.org/10.1135/css201414225.

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Wei, Lu, and Wei Min. "Bioorthogonal vibrational imaging of dynamic metabolism in living organisms." In Novel Techniques in Microscopy. OSA, 2015. http://dx.doi.org/10.1364/ntm.2015.nt2c.3.

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Hudak, Jason, Naama Geva-Zatorsky, and Dennis L. Kasper. "Abstract PR004: Tracking microbial sensing in colorectal cancer using bioorthogonal click chemistry." In Abstracts: CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr15-pr004.

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Hapuarachchige, Sudath, Wenlian Zhu, Yoshinori Kato, and Dmitri Artemov. "Abstract 4572: Bioorthogonal, two-component drug delivery in HER2(+) breast cancer mouse models." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4572.

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Hudak, Jason E., David Alvarez, Ashwin Skelly, Ulrich H. von Andrian, and Dennis L. Kasper. "Abstract PR07: Bioorthogonal chemical labeling of specific immunomodulatory surface molecules in live commensals." In Abstracts: Second CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; September 25-28, 2016; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6066.imm2016-pr07.

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Kumari, S. Lalitha, R. Pandian, and B. Prabhu Dass Batvari. "Medical Image Retrieval Based on Efficient Approach using Bioorthogonal Transform and Encoding Methods." In 2021 International Conference on Advance Computing and Innovative Technologies in Engineering (ICACITE). IEEE, 2021. http://dx.doi.org/10.1109/icacite51222.2021.9404655.

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Rossin, Raffaella, Pascal Renart Verkerk, Sandra M. van den Bosch, et al. "Abstract 4552: Pretargeted radioimmunoimaging and -therapy in tumor-bearing mice using a bioorthogonal reaction." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-4552.

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Hunter, R. C., K. Binder, T. Valentini, S. K. Lucas, L. Cameron, and J. M. Dunitz. "Bioorthogonal Amino Acid Labeling Reveals the Metabolically Active Subpopulation of the Cystic Fibrosis Lung Microbiota." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1209.

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