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Journal articles on the topic 'Biopac'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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1

Giri, Dipti Ramesh, Ekta Singh, and Shanta Satyanarayan. "Comparative study on toxicity evaluation of anaerobically treated parboiled rice manufacturing wastewater through fish bioassay." Water Science and Technology 73, no. 8 (January 19, 2016): 1825–31. http://dx.doi.org/10.2166/wst.2016.029.

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Short term aquatic bioassay has been developed into a useful tool in water quality management. These tests give information on comparative toxicity of several compounds. The objective of this study was to evaluate the acute toxicity of raw and anaerobically treated effluents of the parboiled rice manufacturing industry. The acute toxicity test was carried out by using the fish Lebistes reticulatus under laboratory conditions. LC50 values for 24, 48, 72 and 96 hours ranged between 4.6 and 7.0% for the raw parboiled rice manufacturing wastewater. Two anaerobic fixed film fixed bed reactors and two different media matrices, i.e. UV stabilized Biopac media and Fugino spirals, were used for the treatment of parboiled rice mill wastewater. Effluents from these two reactors depicted LC50 values in the range of 68–88% and 62–78% for Biopac and Fugino spiral packed reactors, respectively. From the results, it is evident that anaerobically treated effluents from Biopac packed reactor is marginally better than Fugino spiral packed reactor. Results subjected to statistical evaluation depicted regression coefficient of more than 0.9 indicating good correlation between the mortality and effluent concentration.
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Martin, Elizabeth A., Rebecca E. Nelson, M. Donna Felmlee-Devine, Troy E. Brown, and Amir Lerman. "Comparing EndoPAT and BIOPAC measurement of vascular responses to mental stress." Cell Biochemistry and Function 29, no. 4 (March 29, 2011): 272–78. http://dx.doi.org/10.1002/cbf.1745.

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Li, Shiwu, Mengzhu Guo, Linhong Wang, Meng Chai, Facheng Chen, and Yunong Wei. "Analysis on the Correlation Degree between the Driver’s Reaction Ability and Physiological Parameters." Mathematical Problems in Engineering 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/5215874.

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In this paper, the correlation degree between driver’s reaction time and the physiological signal is analyzed. For this purpose, a large number of road experiments are performed using the biopac and the reaction time test systems to collect data. First, the electroencephalograph (EEG) signal is processed by using the fast Fourier and the inverse Fourier transforms. Then, the power spectrum densities (PSD) ofα,β,δ, and EEG wave are calculated by Welch procedure. The average power of the power spectrum ofα,β, andθis calculated by the biopac software and two ratio formulas,(α+θ)/βandα/β, are selected to be the impact factors. After that the heart rate and the standard deviation of RR interval are calculated from the electrocardiograph (ECG) signal. Lastly, the correlation degree between the eight impact factors and the reaction time are analyzed based on the grey correlation analysis. The results demonstrate thatα/βhas the greatest correlation to the reaction time except EEG-PSD. Furthermore, two mathematical models for the reaction time-driving time and theα/β-driving time are developed based on the Gaussian function. These mathematical models are then finally used to establish the functional relation ofα/β-the reaction time.
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van Velzen, Marit H. N., Robert Jan Stolker, Arjo J. Loeve, Sjoerd P. Niehof, and Egbert G. Mik. "Comparison between pulse wave velocities measured using Complior and measured using Biopac." Journal of Clinical Monitoring and Computing 33, no. 2 (June 6, 2018): 241–47. http://dx.doi.org/10.1007/s10877-018-0165-9.

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Islam, Monira, Tazrin Ahmed, Md Salah Uddin Yusuf, and Mohiuddin Ahmad. "Cognitive State Estimation by Effective Feature Extraction and Proper Channel Selection of EEG Signal." Journal of Circuits, Systems and Computers 24, no. 02 (November 27, 2014): 1540005. http://dx.doi.org/10.1142/s0218126615400058.

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This paper presents a cognitive state estimation system focused on some effective feature extraction based on temporal and spectral analysis of electroencephalogram (EEG) signal and the proper channel selection of the BIOPAC automated EEG analysis system. In the proposed approach, different frequency components (i) real value; (ii) imaginary value; (iii) magnitude; (iv) phase angle and (v) power spectral density of the EEG data samples during different mental task performed to assess seven types of human cognitive states — relax, mental task, memory related task, motor action, pleasant, fear and enjoying music on the three channels of BIOPAC EEG data acquisition system — EEG, Alpha and Alpha RMS signal. Also the time and time-frequency-based features were extracted to compare the performance of the system. After feature extraction, the channel efficacy is evaluated by support vector machine (SVM) based on the classification rate in different cognitive states. From the experimental results and classification accuracy, it is determined that the overall accuracy for alpha channel shows much improved result for power spectral density than the other frequency based features and other channels. The classification rate is 69.17% for alpha channel whereas for EEG and alpha RMS channel it is found 47.22% and 32.21%, respectively. For statistical analysis standard deviation shows better result for alpha channel and it is found 65.4%. The time-frequency analysis shows much improved result for alpha channel also. For the mean value of DWT coefficients the accuracy is highest and it is 81.3%. Besides the classification accuracy, SVM shows better performance in compare with kNN classifier.
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Ahmad, Mohiuddin, Atiqul Islam, T. T. Khan Munia, M. A. Rashid, and T. M. N. Tunku Mansur. "PHYSIOLOGICAL SIGNAL ANALYSIS FOR COGNITIVE STATE ESTIMATION." Biomedical Engineering: Applications, Basis and Communications 24, no. 01 (February 2012): 57–69. http://dx.doi.org/10.4015/s1016237212002950.

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The purpose of this paper is to identify inconsistency in human physiological signals based on cognitive states by measuring and analyzing bio-signals. In this paper, the cognitive states are estimated using physiological signal analysis. The parameters are electrocardiogram (ECG), electromyogram (EMG), electroencephalogram (EEG) and blood pressure (BP). The signals have been collected using BIOPAC system in which the subjects were induced to undergo the specific sequence of the cognitive state. For getting physiological signals during different conditions, we utilized power point slide show, video clips and question answer method which elicits mental reactions from the subjects. Data is taken before and after four tasks that encompassed the motor action (MA), thought (TH), memory related (MR) and emotion (EM). These measured values are analyzed using BIOPAC Acknowledge software. It was found that the motor action and thought states have effects on BP while MR and EM state mainly affect the ECG measurement. The decibel value and frequency found for EM state in ECG are minimum compared to relaxed state (RS) condition. Similarly, the maximum frequency and dB value is found for MR state. No significant variation was seen for MA and TH states. Thus it was decided that the MR and EM states mainly affect the ECG measurement. For BP the value increases in MA state and decreases in TH state. The MA state mainly affects the EMG signal while other states have no significant changes. The EEG mainly detects the signal of task performed by the specific brain region where the electrodes are placed. In EEG analysis, the electrodes are placed in occipital lobe region which gives mainly the variation in alpha amplitude of EEG with eyes closed and eyes opened. Alpha wave amplitudes vary with the subjects attention to mental tasks performed with eyes closed.
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Arévalo Pachón, Guillermo, and Julio Eduardo Cruz. "La risa contagiosa como vocalización provocadora de expresiones faciales y electromiográficas relacionadas con emociones positivas en los oyentes." Acta Colombiana de Psicología 24, no. 2 (August 12, 2021): 45–58. http://dx.doi.org/10.14718/acp.2021.24.2.5.

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A pesar de su relevancia para la comprensión de la expresión emocional vocal, el estudio de la risa contagiosa se encuentra en sus primeras etapas de investigación y aún no se ha establecido su naturaleza ni la de las respuestas que esta provoca. Teniendo esto en cuenta, el propósito de este estudio fue determinar si los estímulos acústicos de risa contagiosa, además de generar conductas de risa o sonrisa, provocan en los oyentes las expresiones faciales, electromiográficas y cardíacas de una emoción positiva. Para esto, se contó con la participación de 60 universitarios de ambos sexos con edades entre los 18 y los 30 años en un diseño experimental intrasujeto con mediciones en la condición de línea de base y en exposiciones a diferentes estímulos de risa contagiosa, donde se verificaron tres hipótesis en las que se comparó expresiones faciales de alegría (medidas con el software FaceReader), amplitud electromiográfica (emg) del músculo cigomático mayor (medida con el módulo emg-100 del Biopac) e intervalos R-R como indicadores de frecuencia cardíaca (medidos con el módulo ecg-100 del Biopac) entre las diferentes condiciones. Como resultado, se encontraron diferencias significativas en los porcentajes de las expresiones faciales de alegría y amplitud emg del cigomático al comparar las condiciones de línea de base y estímulos de risa más contagiosa, y de risas más y menos contagiosas; no obstante, no se encontraron diferencias significativas en los intervalos R-R en ninguna de las condiciones comparadas. Como conclusión, se comprobó la naturaleza emocional positiva de la risa/sonrisa provocada por estímulos de risa contagiosa y la proporcionalidad entre la intensidad de las expresiones faciales y las respuestas emg elicitadas por esta risa y el grado de contagio percibido de la misma.
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Silva Moreira, Pedro, Pedro Chaves, Ruben Dias, Nuno Dias, and Pedro R. Almeida. "Validation of Wireless Sensors for Psychophysiological Studies." Sensors 19, no. 22 (November 6, 2019): 4824. http://dx.doi.org/10.3390/s19224824.

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James One (MindProber Labs) is a wireless psychophysiological device comprising two sensors: one measuring electrodermal activity (EDA), the other photoplethysmography (PPG). This paper reports the validation of James One’s EDA sensor by comparing its signal against a research grade polygraph. Twenty participants were instructed to perform breathing exercises to elicit the modulation of EDA and heart rate, while the physiological signal was captured simultaneously on James One and a Biopac MP36. The resulting EDA and PPG records collected from both systems were comprehensively compared. Results suggest that James One captures EDA signal with a quality comparable to a research grade equipment, this constituting a reliable means of capturing data while minimizing setup time and intrusiveness.
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Quintero M., Jorge E., and José M. Sierra M. "Diseño y Construcción de un Prototipo de Electrocardiografía Dinámica “Holter” Universal de Tres Canales con Interfaz Electrónica para Cualquier Plataforma de Instrumentación Virtual." Publicaciones e Investigación 7 (June 2, 2013): 99. http://dx.doi.org/10.22490/25394088.1097.

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<p>Este artículo describe el diseño y la construcción de un electrocardiógrafo portátil (Holter) para la adquisición y el almacenamiento de la primera y segunda derivación bipolar ECG, y la derivación precordial. El prototipo construido tiene la ventaja sobre equipos comerciales similares, que descarga las señales almacenadas en forma analógica, lo que permite utilizar cualquier plataforma de instrumentación virtual, entre otras, Labview y Biopac, ya que no dependen de protocolos de comunicación. Las señales de salida del Holter, se compararon con las entradas proporcionadas por un simulador de paciente ECG, donde se encontró una gran similitud en las amplitudes, formas y espectro de frecuencia, sin que se variara el ritmo cardiaco, la señal de interés que el cardiólogo ha de estudiar, en caso de pacientes con arritmias.</p>
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Dwivedi, Pankaj, Kuldipsinh P. Barot, Shailesh Jain, and Manjunath D. Ghate. "Synthesis, Characterization, and Antihypertensive Evaluation of Some Novel 2,2,8,8-Tetramethyl-2,3,7,8-tetrahydro-4,6-diamino-3,7-dihydroxy-6,7-epoxy-benzo-[1,2-b:5,4-b′]dipyran Derivatives." Advances in Chemistry 2015 (January 29, 2015): 1–8. http://dx.doi.org/10.1155/2015/850974.

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A series of 2,2,8,8-tetramethyl-2,3,7,8-tetrahydro-4,6-diamino-3,7-dihydroxy-6,7-epoxy-benzo-[1,2-b:5,4-b′]dipyran derivatives 7a–e and 8a–e were synthesized from resorcinol. All the synthesized compounds were characterized by FTIR, mass spectra, and 1H NMR. These compounds were evaluated for antihypertensive activity using Wister Albino Rat model. Direct antihypertensive activity was performed using the instrument BIOPAC System MP-36 Santa Barbara, California, for recording blood pressure response. Among the title compounds, compounds 7b, 7c, and 7d showed potent antihypertensive activity and other compounds were also found to exert low and moderate antihypertensive activity. The relaxant potency in rat aorta and trachea was used for biological characterization of the benzopyrans. Structure-activity relationships study was investigated around position-4 of the benzopyran nucleus.
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11

Sallo, Dilshad. "DESIGNING SOFTWARE AND EQUIPMENT FOR STANDARD BIPOLAR LEADS TO MEASURE FULL REAL ECG SIGNALS USING BIOPAC SYSTEM." Journal of The University of Duhok 21, no. 2 (November 27, 2018): 18–26. http://dx.doi.org/10.26682/sjuod.2018.21.2.2.

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Khalaj-Hedayati, Kerstin, Anja Bosy-Westphal, Manfred J. Müller, and Manuela Dittmar. "Validation of the BIOPAC indirect calorimeter for determining resting energy expenditure in healthy free-living older people." Nutrition Research 29, no. 8 (August 2009): 531–41. http://dx.doi.org/10.1016/j.nutres.2009.08.001.

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Vulpe, Ana-Maria. "Researches Regarding the Improvement of the Functional Indices Through the Use of Aerobic Gymnastics Means." GYMNASIUM XVIII, no. 2 (December 29, 2017): 135. http://dx.doi.org/10.29081/gsjesh.2017.18.2.10.

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This research aimed to study the probable effects that aerobic gymnastics means could have on the body, for improving the functional indices in female adolescents. The man goal of this research was to improve the female adolescents’ fitness through the use of aerobic gymnastics means, to motivate them for a long term independent practice of physical exercises, both during physical education classes, and during their leisure time. The research comprised a number of 40 subjects (20 female adolescents forming the experimental group, and 20 the control group), aged between 18 and 25, and it was conducted at the “Vasile Alecsandri” University of Bacău. The subjects went through a fitness-type aerobic gymnastics program, three times per week. In order to assess the effectiveness of the applied means, the spirometry test was used, performed with the Biopac system.
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Kher, Rahul, Tanmay Pawar, Vishvjit Thakar, and Dipak Patel. "STUDY OF SPECTRAL CHARACTERISTICS OF MOTION ARTIFACTS IN AMBULATORY ECG BY ANALYZING PCA RESIDUAL ERRORS." Biomedical Engineering: Applications, Basis and Communications 26, no. 02 (March 12, 2014): 1450017. http://dx.doi.org/10.4015/s1016237214500173.

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In this paper, the spectral characteristics of motion artifacts occurring in an ambulatory ECG signal have been studied using principal component analysis (PCA). The PCA residual errors characterize the spectral behavior of the motion artifacts occurring in ambulatory ECG signals. The ECG signals have been acquired from Biopac MP-36 system and a self-developed wearable ECG recorder. The performance is evaluated by power spectral density (PSD) plots of PCA residual errors as well as statistical parameters like mean, median and variance of PCA errors. The PSD plots clearly indicate that the peak frequency of the motion artifacts occurring due to various body movements (like left and right arms up–down, left and right legs up–down, waist twist, walking and sitting up–down) is located around 20–25 Hz against the ECG peak frequency around 5–10 Hz.
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Maheshkumar, K., K. Dilara, KN Maruthy, and L. Sundareswaren. "Validation of PC-based sound card with Biopac for digitalization of ECG recording in short-term HRV analysis." North American Journal of Medical Sciences 8, no. 7 (2016): 307. http://dx.doi.org/10.4103/1947-2714.187150.

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Nowakowski, Przemysław, Wojciech Uchto, Eugeniusz Hrycek, Mateusz Kachel, Tomasz Ludyga, Filip Polczyk, Aleksander Żurakowski, et al. "Microcrystalline paclitaxel-coated balloon for revascularization of femoropopliteal artery disease: Three-year outcomes of the randomized BIOPAC trial." Vascular Medicine 26, no. 4 (March 9, 2021): 401–8. http://dx.doi.org/10.1177/1358863x20988360.

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The aim of the BIOPAC trial was to determine long-term safety and efficacy of a novel microcrystalline paclitaxel-coated balloon (mcPCB) with a biocompatible polymer as an excipient in the treatment of occlusive femoropopliteal lesions. In this first-in-human prospective controlled randomized trial, 66 patients with femoropopliteal, symptomatic (Rutherford stages 2B to 5) occlusive arterial disease were randomized to either mcPCB (study group) or POBA (plain old balloon angioplasty) (control group) on a 1:1 basis. Late lumen loss (LLL) at 6 months was the primary endpoint of the study and serious adverse events (SAE: death, amputation, repeated revascularization) were considered a composite secondary endpoint. Routine angiography was scheduled for all study subjects at 6-month follow-up; outpatient appointments were scheduled at 12 and 36 months after intervention. At 6 months, the LLL was 63% lower in the mcPCB group compared to the POBA group (0.52 ± 1.2 vs 1.39 ± 1.1 mm; psup < 0.01). Binary restenosis occurred in 23% vs 52% of patients ( p = 0.02). At 3 years, the prevalence of SAE was significantly lower in the mcPCB group (33.3 vs 63.3%; p = 0.02), which mainly resulted from a twofold reduction in target vessel revascularization rate (28.6 vs 59.3%; p = 0.02). The difference in mortality was nonsignificant (7.4 vs 14.3%; p = 0.42). Patients with mcPCB were less symptomatic and less likely to adhere to secondary prevention measures. In this pivotal trial, a novel mcPCB proved superior to POBA concerning LLL at 6-month follow-up, and SAE at 12 months. This result was sustained up to 3 years. There was no difference between groups regarding mortality. ClinicalTrials.gov Identifier: NCT02145065
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Bethiun, Dr S., and Dr R. Premaraja. "Effect of Type 2 Diabetes Mellitus on Cognitive function and EEG in elderly patients." International Journal Of Medical Science And Clinical Invention 5, no. 3 (March 22, 2018): 3678–80. http://dx.doi.org/10.18535/ijmsci/v5i3.21.

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Introduction: Diabetes is a major health problem in India, Type 2 is also the most common type seen. Diabetes is associated with cognitive decline in elderly patients. Hyperglycemia, age, sex and duration of diabetes mellitus all seems to affect cognitive function. Objectives: Aim of the study is to assess the EEG changes and cognitive function in elderly type 2 diabetes mellitus patients. Materials and methods: Two groups of people, 20 in each group who are age sex matched were selected and case group of elderly diabetic patients and control group of healthy subjects were selected. EEG recordings were done using MP36 – BIOPAC 4 channel instrument and cognitive function was assessed using MMSE. Results: The elderly diabetic group was having declined cognitive function – MCI (Mild Cognitive Impairment) and reduced EEG wave activity. Conclusion: Reduced EEG alpha wave activity is seen in elderly diabetic patients. Reduced functional connections in cortex and hyperglycemia induced pathologic changes could be the causative factors.
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Miller, John P., and Ronald V. Croce. "Analyses of Isokinetic and Closed Chain Movements for Hamstring Reciprocal Coactivation." Journal of Sport Rehabilitation 16, no. 4 (November 2007): 319–25. http://dx.doi.org/10.1123/jsr.16.4.319.

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Context:Researchers have postulated that coactivation of the hamstrings during active knee extension assists the anterior cruciate ligament in maintaining knee joint stability by exerting an opposing force to anterior tibial translation.Objective:To compare the reciprocal coactivation of the hamstrings while performing low and high velocity isokinetic movements and two closed chain movements.Design:Within subject’s comparison of isokinetic and closed chain exercises.Setting:Biomechanics laboratory utilizing a Cybex norm isokinetic dynamometer and Biopac Data Collection system.Participants:12 healthy women.Main Outcome Measures:The root mean square of the Electromyogram (rmsEMG) was used as a measure of overall muscle activity.Results:The rmsEMG for hamstring coactivation during knee extension showed significant differences between the isokinetic movements and the closed chain exercises with greater coactivation when performing the isokinetic movements. In addition, greater activity was seen at the higher isokinetic velocity and during the one legged squat.Conclusions:These results suggest isokinetic movements, particularly at high speed, can more effectively increase the coactivation activity of the hamstrings when compared to two closed chain activities.
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Soldatov, Vladislav O., Tatyana N. Malorodova, Tatiana I. Balamutova, Andrey O. Ksenofontov, Anton P. Dovgan, and Zhanna S. Urozhevskaya. "Endothelial dysfunction: comparative evaluation of ultrasound dopplerography, laser dopplerflowmetry and direct monitoring of arterial pressure for conducting pharmacological tests in rats." Research Results in Pharmacology 4, no. 1 (March 28, 2018): 73–80. http://dx.doi.org/10.3897/rrpharmacology.4.25529.

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Introduction: The importance of the problem of endothelial dysfunction makes it essential to improve approaches to its evaluation. Due to the high diagnostic potential of ultrasound dopplerography, this method is promising in the study of endothelial function. Objective:To study endothelial function when conducting vascular pharmacological tests in the norm and with the blockade of the nitric oxide synthesis by means of the ultrasound method for examining the central blood flow velocity in the femoral artery of the rat in comparison with changes of systemic haemodynamics and microcirculation velocity in the medial vastus muscle using laser Doppler flowmetry. Materials and methods: In the norm and in conditions of deficiency of endogenous nitric oxide, three methods for assessing haemodynamics were used simultaneously: 1) dopplerography using the ultrasoundDoppler system (Minimax-Doppler-K, St Petersburg); 2) laser doppler flowmetry using the TDS144 sensor (Biopac MP-150, USA); 3) recording the arterial pressure in the carotid artery by means of a catheter connected to a TDS-160-A sensor (Biopac MP-150, USA). To study the vasoregulatory function of the endothelium under conditions of multicomponent monitoring of haemodynamics, functional vascular tests were performed using acetylcholine and sodium nitroprusside. Results: Quantification of endothelial dysfunction when conducting pharmacological tests with endothelium-dependent (acetylcholine) and endothelium-independent (sodium nitroprusside) vasodilation is most significant when calculating the coefficient reflecting the ratio of areas of vascular response. Theblood flow velocity parameters recorded by using Doppler ultrasound showed a high correlation level with both arterial pressure and with a linear microcirculation rate. The most comprehensive dopplerographic indices for evaluating the function of the endothelium by conducting pharmacological tests in the norm and in the case of pathology, are the estimated systolic-diastolic difference in blood flow velocities (ΔVs-Vd) in the femoral artery. The study of the endothelial function when conducting vascular pharmacological tests in the norm and with nitric oxide synthesis blockaded, by means of the ultrasound examination of the central blood flow velocity in the femoral artery, is comparable to changing the haemodynamics parameters as well as velocity in microcirculation of the medial vastus muscle using laser Doppler flowmetry. Conclusions: Ultrasonic dopplerography using the Minimax-Doppler-K device reflects the systemic and local vascular response to the administration of vasodilators both in the norm and with the blockade of the nitric oxide synthesis and makes it possible to conduct an informative assessment of the endothelial function.
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Cotter, Paul A., and Kenneth J. Rodnick. "Fishing for an ECG: a student-directed electrocardiographic laboratory using rainbow trout." Advances in Physiology Education 31, no. 2 (June 2007): 211–17. http://dx.doi.org/10.1152/advan.00096.2006.

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Cardiac physiology is emphasized in many undergraduate physiology courses, but few nonmammalian vertebrate model systems exist that 1) can be studied fairly noninvasively, 2) are well suited for controlled experimentation, and 3) emphasize principles characteristic of the vertebrate heart. We have developed an inquiry-based undergraduate/graduate-level laboratory in cardiac physiology and electrocardiography using rainbow trout ( Oncorhynchus mykiss Walbaum) and the BioPac MP30 data-acquisition system (other fish species and/or electrocardiographic recording devices can be substituted). This laboratory facilitates intensive study of vertebrate electrocardiograms (ECGs) under a variety of environmental and physiological perturbations and is ideal for use in multisession, inquiry-based laboratory projects in animal physiology. Furthermore, students gain valuable experience in scientific inquiry, study design, following and/or developing scientific protocols, and animal care. This laboratory requires the ability to keep captive fish of at least 100 g and equipment to record ECGs. Departments meeting these requirements can adopt this technique at modest expense. Student enthusiasm and feedback were positive, and several students commented that the nonlethal methods used added to the laboratory's perceived value.
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Zhang, Yule, and Shoulin Zhu. "Study on the Effect of Driving Time on Fatigue of Grassland Road Based on EEG." Journal of Healthcare Engineering 2021 (July 8, 2021): 1–9. http://dx.doi.org/10.1155/2021/9957828.

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In order to study the change law of the fatigue degree of grassland expressway drivers over time, this paper takes the semidesert grassland landscape of Xilinhot city as the experimental environment and takes the provincial highway S101 (K278–K424) as an example to design an actual driving test. Taking Urumqi, Inner Mongolia Autonomous Region, as the experimental section, combined with the Biopac MP150 multichannel physiological instrument and its auxiliary knowledge software and mathematical statistics methods, the relationship between EEG and time was studied. The test results show that the primary fatigue factor F1 and the secondary fatigue factor F2 can summarize the fatigue law characterized by 96.42% of EEG information. During 130 minutes of driving on the prairie highway, the periods of high fatigue were 105 minutes and 125 minutes, respectively. Driving fatigue can be divided into three stages over time: 5–65 min fatigue-free stage, 70–85 min fatigue transition stage, and 90–130 min fatigue stage. Fatigue changes over time. The law follows the Gaussian function and the sine function.
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Prati, José Eduardo Lattari Rayol. "Efeitos do horário do dia no desenvolvimento de força isométrica máxima em adolescentes não treinados." Revista Brasileira de Fisiologia do Exercício 8, no. 3 (September 10, 2009): 121. http://dx.doi.org/10.33233/rbfe.v8i3.3567.

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O presente estudo investigou os efeitos do horário do dia no desenvolvimento de força isométrica máxima em adolescentes não treinados. Participaram do estudo 20 adolescentes na faixa etária15 a17 anos, gênero masculino. 10 participantes treinaram força isométrica máxima no horário vespertino entre 15:00 h e 18:00 h e os outros 10 treinaram o mesmo em horário diurno entre 7:00 h e 10:00 h. Ambos os grupos foram submetidos a um teste de força isométrica máxima para os músculos flexores de cotovelo para qual foi utilizado um transdutor de força Biopac de modelo TSD130c. O treinamento foi realizado em dias alternados, em horários vespertinos para um grupo e diurno, para o outro. O programa ocorreu em 3 sessões semanais durante 4 semanas, onde 3 séries de 5 contrações máximas com 5 segundos e intervalo de 1 minuto foram executados. Os resultados revelaram uma diferença significativa entre os períodos, sendo p < 0,05, favorecendo o grupo treinado no horário vespertino. Conclui-se que o treinamento de força isométrica realizado no horário vespertino produziu maiores ganhos de quando comparados ao horário diurno para esses adolescentes.Palavras-chave: horário do dia, força isométrica, adolescentes.
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Benavides Henao, Diego Armando, Natalia Campuzano Piedrahita, Luz Clemencia Henao Palacio, Isora Andrea Hoyos Escobar, Luis Fernando Jaramillo, Nathaly Marin Correa, Cristian Mauricio Osorio, Angela Maria Ramirez, Oscar Castaño Valencia, and Jose Jaime Castaño Castrillon. "Caracterizacion Electrocardiografica En Estudiantes De Ciencias De La Salud De Manizales, Segun Antecedentes Familiares De Infarto De Miocardio." Archivos de Medicina (Manizales) 13 (June 30, 2013): 23–37. http://dx.doi.org/10.30554/archmed.13.0.1378.2006.

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INTRODUCCION: El Infarto Agudo de Miocardio (IAM), constituye una de las principalescausas de muerte y discapacidad en el medio, es por esto que su diagnósticoes de vital importancia. La utilización del electrocardiograma contiene un invaluablepronóstico de información relacionada con: tamaño del corazón, desviación del segmentoS-T, duración de QRS y localización del infarto. Esta información sumada a lapredicción clínica, debe ser valorada para facilitar la mejor opción de tratamiento.MATERIALES Y METODOS: Estudio descriptivo, transversal con base en la caracterizaciónelectrocardiográfica y variables poblaciones, en 76 estudiantes entre los16-35 años de edad de las facultades de Medicina y Psicología de la Universidad deManizales, en forma voluntaria. Se indagó sobre diversas variables demográficas, yfactores de riesgo para IAM, y se empleó el sistema BIOPAC MP30 para la determinacióndel electrocardiograma (EKG).RESULTADOS: Promedio de edad 22 años, 45 mujeres, 31 hombres, Indice de MasaCorporal (IMC) promedio 22.7 Kg/m2. Promedio de PAS 110mmHg, PAD 70mmHg,fumadores 30.3%, consumo de bebidas 77.6%, consumo sustancias psicoactivas13.2%, antecedentes personales: HTA 9,2%, palpitaciones 38.2%, dolor torácico 40.8%.Antecedentes familiares: HTA 76.3%, dolor torácico 52.6%. Variables electrocardiográficas:onda P bífida 32.9%, qRs 34.2%, ritmo sinusal 100%, FC promedio 75 LPM,supradesnivel ST 3.9%.
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Xu, Lingling, Dou Tang, Meiping Guan, Cuihua Xie, and Yaoming Xue. "Effect of High-Fat Diet on Peripheral Neuropathy in C57BL/6 Mice." International Journal of Endocrinology 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/305205.

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Objective. Dyslipidemia may contribute to the development of peripheral neuropathy, even in prediabetics; however, few studies have evaluated vascular dysfunction and oxidative stress in patients with peripheral neuropathy.Methods. Using high-fat diet- (HFD-) induced prediabetic C57BL/6 mice, we assessed motor and sensory nerve conduction velocity (NCV) using a BIOPAC System and thermal algesia with a Plantar Test (Hargreaves’ method) Analgesia Meter. Intraepidermal nerve fiber density and mean dendrite length were tested following standard protocols. Vascular endothelial growth factor-A (VEGF-A) and 12/15-lipoxygenase (12/15-LOX) were evaluated by immunohistochemistry and Western blot, respectively.Results. HFD-fed mice showed deficits in motor and sensory NCV, thermal hyperalgesia, reduced mean dendrite length, and VEGF-A expression in the plantar skin and increased 12/15-LOX in the sciatic nerve (P<0.05compared with controls).Conclusion. HFD may cause large myelinated nerve and small sensory nerve fiber damage, thus leading to neuropathy. The mean dendrite length may be a more sensitive marker for early detection of peripheral neuropathy. Reduced blood supply to the nerves and increased oxidative stress may contribute to the development and severity of peripheral neuropathy.
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Suvorov, Nikolai B., Alexander V. Belov, Konstantin G. Kuliabin, Aleksei A. Anisimov, Timofei V. Sergeev, and Oleg A. Markelov. "High Precision Human Skin Temperature Fluctuations Measuring Instrument." Sensors 21, no. 12 (June 15, 2021): 4101. http://dx.doi.org/10.3390/s21124101.

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This paper describes the experimental results of testing a prototype of a high precision human skin rapid temperature fluctuations measuring instrument. Based on the author’s work, an original circuit solution on a miniature semiconductor diode sensor has been designed. The proposed circuitry provides operation in the full voltage range with automatic setting and holding the operating point, as well as the necessary slope of the conversion coefficient (up to 2300 mV/°C), which makes it possible to register fast temperature oscillations from the surface of the human body and other biological objects. Simulation results in the Microcap 12 software and laboratory tests have confirmed all declared design specifications: temperature resolution of 0.01 °C, transducer thermal time constant of 0.05 s. An original thermostat and an experimental setup for the simultaneous registration of the electrocardiogram, pulse wave signals from the Biopac polygraph MP36 and a signal of temperature oscillations from the prototype thermometer have been designed for further investigations. The preliminary test results indicates that using the designed measuring instrument gives a possibility to provide an in-depth study of the relationship between micro- and macro-blood circulations manifested in skin temperature fluctuations.
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Nowakowski, Przemek. "TCTAP A-042 Microcrystalline Paclitaxel Coated Balloon for Revascularization of Femoro-popliteal Artery Disease: Three-year Outcomes of the Randomized BIOPAC Trial." Journal of the American College of Cardiology 77, no. 14 (April 2021): S26. http://dx.doi.org/10.1016/j.jacc.2021.03.072.

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Marques, Carlos J., Christian Bauer, Dafne Grimaldo, Steffen Tabeling, Timo Weber, Alexander Ehlert, Alexandre H. Mendes, Juergen Lorenz, and Frank Lampe. "Sensor Positioning Influences the Accuracy of Knee Rom Data of an E-Rehabilitation System: A Preliminary Study with Healthy Subjects." Sensors 20, no. 8 (April 15, 2020): 2237. http://dx.doi.org/10.3390/s20082237.

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E-rehabilitation is the term used to define medical rehabilitation programs that are implemented at home with the use of information and communication technologies. The aim was to test whether sensor position and the sitting position of the patient influence the accuracy of knee range of movement (ROM) data displayed by the BPMpathway e-rehabilitation system. A preliminary study was conducted in a laboratory setting with healthy adults. Knee ROM data was measured with the BPMpathway e-rehabilitation system and simultaneously with a BIOPAC twin-axis digital goniometer. The main outcome was the root mean squared error (RMSE). A 20% increase or reduction in sitting height led to a RMSE increase. A ventral shift of the BPMpathway sensor by 45° and 90° caused significant measurement errors. A vertical shift was associated with a diminution of the measurement errors. The lowest RMSE (2.4°) was achieved when the sensor was placed below the knee. The knee ROM data measured by the BPMpathway system is comparable to the data of the concurrent system, provided the instructions of the manufacturer are respected concerning the sitting position of the subject for knee exercises, and disregarding the same instructions for sensor positioning, by placing the sensor directly below the knee.
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Zhao, Yang, Zhi-Nan Zheng, Xiang Liu, Gang Dai, and San-Qing Jin. "Effects of preconditioned plasma collected during the late phase of remote ischaemic preconditioning on ventricular arrhythmias caused by myocardial ischaemia reperfusion in rats." Journal of International Medical Research 46, no. 4 (February 13, 2018): 1370–79. http://dx.doi.org/10.1177/0300060518755268.

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Objective The administration of preconditioned plasma collected during the late phase of preconditioning has been shown to reduce myocardial infarct size. This study aimed to investigate if preconditioned plasma could attenuate ventricular arrhythmias in a rat model in vivo. Methods Eighty rats were randomized to eight groups (10 rats/group). Two groups provided preconditioned or non-preconditioned plasma 48 h after transient limb ischaemia or the control protocol. Six groups of ischaemia-reperfusion (IR) rats received normal saline, non-preconditioned plasma, or preconditioned plasma, respectively, 1 h (groups A1, A2, A3) or 24 h (groups B1, B2, B3) before undergoing myocardial IR. Electrocardiograms were monitored using a BIOPAC system, and the incidence and duration of ventricular tachycardia (VT) and ventricular fibrillation (VF) were analysed. Results No significant differences existed in the incidence and duration of VT or VF among groups A1–A3 or in the incidence and duration of VT among groups B1–B3. However, there was a significantly lower incidence and shorter duration of VF in group B3 rats than in group B1 rats. Conclusion Preconditioned plasma collected during the late phase of preconditioning can reduce the incidence and duration of VF compared with normal saline, suggesting its anti-arrhythmic potential.
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Mohaddes, Farzad, Rafael da Silva, Fatma Akbulut, Yilu Zhou, Akhilesh Tanneeru, Edgar Lobaton, Bongmook Lee, and Veena Misra. "A Pipeline for Adaptive Filtering and Transformation of Noisy Left-Arm ECG to Its Surrogate Chest Signal." Electronics 9, no. 5 (May 23, 2020): 866. http://dx.doi.org/10.3390/electronics9050866.

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The performance of a low-power single-lead armband in generating electrocardiogram (ECG) signals from the chest and left arm was validated against a BIOPAC MP160 benchtop system in real-time. The filtering performance of three adaptive filtering algorithms, namely least mean squares (LMS), recursive least squares (RLS), and extended kernel RLS (EKRLS) in removing white (W), power line interference (PLI), electrode movement (EM), muscle artifact (MA), and baseline wandering (BLW) noises from the chest and left-arm ECG was evaluated with respect to the mean squared error (MSE). Filter parameters of the used algorithms were adjusted to ensure optimal filtering performance. LMS was found to be the most effective adaptive filtering algorithm in removing all noises with minimum MSE. However, for removing PLI with a maximal signal-to-noise ratio (SNR), RLS showed lower MSE values than LMS when the step size was set to 1 × 10−5. We proposed a transformation framework to convert the denoised left-arm and chest ECG signals to their low-MSE and high-SNR surrogate chest signals. With wide applications in wearable technologies, the proposed pipeline was found to be capable of establishing a baseline for comparing left-arm signals with original chest signals, getting one step closer to making use of the left-arm ECG in clinical cardiac evaluations.
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Arquilla, Katya, Andrea Webb, and Allison Anderson. "Textile Electrocardiogram (ECG) Electrodes for Wearable Health Monitoring." Sensors 20, no. 4 (February 13, 2020): 1013. http://dx.doi.org/10.3390/s20041013.

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Wearable health-monitoring systems should be comfortable, non-stigmatizing, and able to achieve high data quality. Smart textiles with electronic elements integrated directly into fabrics offer a way to embed sensors into clothing seamlessly to serve these purposes. In this work, we demonstrate the feasibility of electrocardiogram (ECG) monitoring with sewn textile electrodes instead of traditional gel electrodes in a 3-lead, chest-mounted configuration. The textile electrodes are sewn with silver-coated thread in an overlapping zig zag pattern into an inextensible fabric. Sensor validation included ECG monitoring and comfort surveys with human subjects, stretch testing, and wash cycling. The electrodes were tested with the BIOPAC MP160 ECG data acquisition module. Sensors were placed on 8 subjects (5 males and 3 females) with double-sided tape. To detect differences in R peak detectability between traditional and sewn sensors, effect size was set at 10% of a sample mean for heart rate (HR) and R-R interval. Paired student’s t-tests were run between adhesive and sewn electrode data for R-R interval and average HR, and a Wilcoxon signed-rank test was run for comfort. No statistically significant difference was found between the traditional and textile electrodes (R-R interval: t = 1.43, p > 0.1; HR: t = −0.70, p > 0.5; comfort: V = 15, p > 0.5).
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Zacaron, Katy Andrade Monteiro, João Marcos Domingues Dias, Mariana Asmar Alencar, Luane Landim de Almeida, Carlos Alberto Mourão-Júnior, and Rosângela Correa Dias. "Electromyographic normalization of vastus lateralis and biceps femoris co-contraction during gait of elderly females." Fisioterapia em Movimento 29, no. 4 (December 2016): 787–94. http://dx.doi.org/10.1590/1980-5918.029.004.ao15.

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Abstract Introduction: Analyze muscle co-contraction using electromyographic signals, which are normalized to compare individuals, muscles and studies. Maximum voluntary isometric contraction (MVIC) and peak electrical activity (PEA) during movement are the most widely used forms of normalization. Objective: Compare inter-subject variability and investigate the association between the co-contraction indices of the vastus lateralis and biceps femoris during gait, normalized by MVIC and PEA. Methods: Thirty elderly women, aged 70.33 ± 3.69 years took part. Electrical muscle activity during MVIC and gait was recorded using a Biopac MP100 electromyograph. MVIC was performed in a Biodex isokinetic dynamometer. For normalization, the signals were divided by the Root Mean Square values of MVIC and PEA of gait. Results: The coefficient of variation of non-normalized data was 69.3%, and those normalized by PEA and MVIC were 30.4% and 48.9% respectively. Linear regression analysis resulted in a prediction model: PEA = 0.04 + 0.16 x MVIC. The goodness of fit of the regression model was statistically significant (p=0.02). The confidence interval (95% CI) for the intercept was between 0.02 and 0.29 and for MVIC between 0.03 and 0.06. Conclusions: The data normalized by PEA showed less variation than those normalized by MVIC. A 100% variation in data normalized by MVIC resulted in a 16% variation in data normalized by PEA, while variation in normalization by MVIC accounts for 17% of the variation in normalization by PEA and vice versa.
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Klimenko, Aleksey V., Sergey S. Pertsov, Igor Yu Yakovenko, Eugene I. Levkin, Timur U. Samratov, and Marina S. Gubenko. "Physiological ‘cost’ of activity of individuals with different effectiveness in dynamics of endosurgical training." I.P. Pavlov Russian Medical Biological Herald 27, no. 3 (October 8, 2019): 333–41. http://dx.doi.org/10.23888/pavlovj2019273333-341.

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Aim. The work was designed to study the physiological ‘cost’ of purposeful behavior on the model of endosurgical training. Materials and Methods. The research was implemented on 87 men of 18-24 years of age. The volunteers per formed a number of exercises 30 minutes each according to the Basic Endosurgical Simulation Training and Attestation System (BESTA system) on a T5 Large RM box-trainer within 10 consecutive days. The total time and the number of mistakes were recorded. During the training sessions an electromyogram was recorded on a BIOPAC MP 36 device. ECG was recorded and processed using a Varicard 2.51 device before and after the training sessions. ECG was analyzed by evaluation of the average differences of spectral analysis of heart rate variability before and after training. Results. It was shown that high-performance individuals were characterized by less energy spent on motor work in purposeful activity. Irrespective of the effectiveness of training, the purposeful behavior in conditions of psychoemotional stress was characterized by depletion of functional reserves of an organism. Low-performance subjects demonstrated a more evident weakening of parasympathetic (start of observations) and of sympathetic influences (end of observations) on the functional activity of the heart. Conclusion. Specific features of physiological ‘cost’ of purposeful behavior in individuals with different effectiveness of the activity were revealed on the model of endosurgical training. Better results in the dynamics of purposeful activity were achieved on this model at a higher physiological ‘cost’.
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Maity, Payel, Sujaya De, Amitava Pal, Hiranmoy Mahata, Mousumi Chatterjee, and Prakash C. Dhara. "Identification of a suitable working posture for female workers engaged in golden thread work." International Journal of Occupational Safety and Health 4, no. 2 (March 17, 2016): 24–33. http://dx.doi.org/10.3126/ijosh.v4i2.14666.

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Background: The golden thread (jori) work is one of the major home based industries providing employment to thousands of artisans spread over several rural areas of the West Bengal. The study is essentially labor intensive and thus workers are prone to suffer from work related health problems. Objective: The present study was aimed to evaluate the musculoskeletal disorders (MSDs) and postural stress of the female golden thread workers. Methods: The study was carried on 123 adult female golden thread workers in different districts of West Bengal. The prevalence of MSD, body part discomfort rating (BPD) and postural stress (by OWAS, RULA, REBA method) of the workers were evaluated by standard methods. The EMG of shoulder and back muscle was recorded with the help of the BIOPAC system. Result: The results showed that the prevalence of MSDs, BPD rating and postural stress were comparatively lower in case of sitting on the floor with folded legs than squatting and sitting on the floor with stretched legs. The EMG and RMS values of EMG voltage of shoulder and back muscle were comparatively lower in this posture than that of other two postures. Conclusion: It was therefore, concluded that sitting on the floor with folded legs was less hazardous and it imposed less postural stress in comparison to other sitting postures adopted by the golden thread workers.International Journal of Occupational Safety and Health, Vol 4 No 2 (2014) 24 – 33
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Liu, Boyan, Liuyang Han, Lyuming Pan, Hongzheng Li, Jingjing Zhao, Ying Dong, and Xiaohao Wang. "Flexible Multiscale Pore Hybrid Self-Powered Sensor for Heart Sound Detection." Sensors 21, no. 13 (June 30, 2021): 4508. http://dx.doi.org/10.3390/s21134508.

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This research introduces an idea of producing both nanoscale and microscale pores in piezoelectric material, and combining the properties of the molecular β-phase dipoles in ferroelectric material and the space charge dipoles in order to increase the sensitivity of the sensor and modulate the response frequency bandwidth of the material. Based on this idea, a bi-nano-micro porous dual ferro-electret hybrid self-powered flexible heart sound detection sensor is proposed. Acid etching and electrospinning were the fabrication processes used to produce a piezoelectric film with nanoscale and microscale pores, and corona poling was used for air ionization to produce an electret effect. In this paper, the manufacturing process of the sensor is introduced, and the effect of the porous structure and corona poling on improving the performance of the sensor is discussed. The proposed flexible sensor has an equivalent piezoelectric coefficient d33 of 3312 pC/N, which is much larger than the piezoelectric coefficient of the common piezoelectric materials. Experiments were carried out to verify the function of the flexible sensor together with the SS17L heart sound sensor (BIOPAC, Goleta, California, USA) as a reference. The test results demonstrated its practical application for wearable heart sound detection and the potential for heart disease detection. The proposed flexible sensor in this paper could realize batch production, and has the advantages of flexibility, low production cost and a short processing time compared with the existing heart sound detection sensors.
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Nowakowski, Przemyslaw, Piotr Buszman, Juan Granada, Robert Stefan Kiesz, and Paweł Buszman. "FJVIS 38. Three-Year Follow-up in BIOPAC Trial—Treating Lesions in Femoropopliteal Segment Using Microcrystalline and Biocompatible Polymer Paclitaxel-Coated Balloon Versus Plain Balloon Angioplasty." Journal of Vascular Surgery 70, no. 5 (November 2019): e203. http://dx.doi.org/10.1016/j.jvs.2019.08.222.

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Deufel, Bernhard, Carsten Mueller, Gavan Duffy, and Tom Kevenaar. "BioPACE." Datenschutz und Datensicherheit - DuD 37, no. 6 (June 2013): 363–66. http://dx.doi.org/10.1007/s11623-013-0141-y.

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Elduque, Albert. "Biopic vs Biopic: Comparing Cinematic Lives." Comparative Cinema 9, no. 16 (July 15, 2021): 6–9. http://dx.doi.org/10.31009/cc.2021.v9.i16.01.

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Peresypkina, Anna A. "Correction of ischemic optic neuropathy in rats by carbamylated darbepoetin." Research Results in Pharmacology 4, no. 1 (March 28, 2018): 43–50. http://dx.doi.org/10.3897/rrpharmacology.4.25262.

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Introduction: The protective effects of carbamylated darbepoetin on the model of ischemic optic neuropathy in rats were revealed. Objectives: To increase the effectiveness of pharmacological correction of experimental ischemic optic neuropathy in an experiment by using carbamylated darbepoetin. Methods: Measuring the microcirculation level in the retina of rats was carried out using laser Doppler flowmetry (LDF). Registration was done by the data acquisition system Biopac-systems MP-150 and AcqKnowledge 4.2 programme. For microscopy and morphometry, the prepared microslides were scanned using Mirax Desk, a computerised archiving and image analysis system. Image analysis and morphometry were carried out by Pannoramic Viewer 1.15.4. Results and discussion: In the group with correction of ischemic optic neuropathy by carbamylated darbepoetin, 300 μg/kg, the microcirculation level increases by 41.9%, p&lt;0.05 in comparison with the control group, but also below the norm values by 20.3%, p&lt;0.05. In the group with correction by recombinant erythropoietin, 50 IU/kg, the microcirculation rate increases by 36.7%, p&lt;0.05 in comparison with the control group and significantly lower - by 23.3%, p&lt;0.05 - in comparison with the group of intact animals. Qualitative and quantitative morphological indices (thickness of retinal layers) helped to reveal a neuroprotective effect of carbamylated darbepoetin to a greater extent than that of recombinant erythropoietin. Conclusion: The obtained data allow drawing a conclusion about partial restoration of blood flow and preservation of neuronal retinal structures when correcting ischemic optic neuropathy in rats with carbamylated darbepoetin to a greater extent than with recombinant erythropoietin.
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Vasiliev, P. V., A. N. Shishkin, N. P. Erofeev, N. A. Bubnova, and I. Y. Pchelin. "Non-invasive assessment of microcirculation in patients with late-stage complications of diabetes mellitus type 2." Regional blood circulation and microcirculation 14, no. 4 (December 30, 2015): 28–33. http://dx.doi.org/10.24884/1682-6655-2015-14-4-28-33.

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The aim of our study was to assess of microcirculation using laser Doppler flowmetry (LDF) in patients with diabetic foot syndrome (DFS) caused by diabetes mellitus type 2. Materials and methods. The main group consisted of 16 patients with DFS. In the control group, 19 patients without diabetes mellitus were included. An LDF investigation was performed using Biopac LDF 100C system. Estimated glomerular filtration rate (eGFR) was determined using CKD-EPI formula. Results and discussion. According to LDF, patients with DFS had the severe form of microcirculatory failure, with abrupt worsening of venous drainage, caused by venous lesion during the diabetic microangiopathy. The marker LDF phenomena were decreasing of flaxmotion index, low- and high-frequency flaxmotions contribution and increasing of high-frequency flaxmotion contribution. During the eGFR decreasing in the main group a simultaneous decreasing of low-frequency flaxmotion contribution and flaxmotion index, also with increasing of high-frequency flaxmotions contribution and intravascular resistance shows to stazic form of microcirculatory disorder. Exposed correlations of LDF-indexes with eGFR can show that LDF has potential possibilities for diagnostics and progression assessment of microangiopathic changes. Summary. In patients with diabetes mellitus type 2, a progressive microcirculation failure takes place. With the development of the microangiopathy, a negative influence of venous stasis prevails over the ischemic events. The development of chronic kidney disease is an independent risk-factor of microangiopathic complications of diabetes mellitus type 2. Preclinical diagnostics of renal lesion is important for timely beginning of the protective therapy of severe microvascular complications.
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Doufesh, Hazem, Fatimah Ibrahim, Noor Azina Ismail, and Wan Azman Wan Ahmad. "APPLICATION OF SELF ORGANIZING MAP FOR CORRELATION HUNTING BETWEEN ALPHA BAND POWER OF EEG SIGNALS AND OTHER PHYSIOLOGICAL PARAMETERS DURING MUSLIM PRAYER (SALAT)." Biomedical Engineering: Applications, Basis and Communications 30, no. 04 (August 2018): 1850029. http://dx.doi.org/10.4015/s1016237218500291.

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This study investigates a new approach to determine the correlations between alpha ([Formula: see text]) electroencephalography (EEG) and other physiological parameters during Muslim prayer (Salat) utilizing the self organizing map (SOM). The powerfulness of SOM in visualizing, understanding, and exploring the complexity in multivariable data can be used to determine the relationships between the input variables. Thirty healthy Muslim male subjects were recruited in the study. Their electroencephalogram (EEG), electrocardiogram (ECG), respiration rate (RSP), and oxygen saturation (SPO2) were continuously recorded using computer-based data acquisition system (MP150, BIOPAC Systems Inc., Camino Goleta, California). Three maps were constructed to determine the correlations in pre-baseline, during Salat, and post-baseline conditions utilizing SOM. The visualized results during Salat indicated that, alpha power (P[Formula: see text]) showed significant positive correlation in the occipital and parietal electrodes with the normalized unit of high-frequency HF (n.u.) power of heart rate variability (HRV) components (as a parasympathetic index), heart rate (HR), and RSP. Significant negative correlation was also observed between P[Formula: see text] with the normalized unit of low-frequency LF (n.u.) power and LF/HF of HRV (as sympathetic indices). SPO2 showed no correlation with P[Formula: see text]. While the results in pre-baseline and post-baseline conditions also did not show any correlation between the variables. The SOM proves that it can be successfully employed as a powerful technique in correlation analysis. The results were presented and compared with a previous study. Thus, it can be applied successfully in various biomedical engineering applications.
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Cornick, Jessica E., and Jim Blascovich. "Physiological Responses to Virtual Exergame Feedback for Individuals with Different Levels of Exercise Self-Efficacy." International Journal of Virtual Reality 17, no. 1 (January 1, 2017): 32–53. http://dx.doi.org/10.20870/ijvr.2017.17.1.2886.

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OBJECTIVE: Exercise videogames are increasingly popular as individuals seek to increase their activity. This study assessed the interaction of exercise self-efficacy (ESE) levels and perceived task demands of a virtual game on exercise and physiological reactions. Perceived task demands were manipulated by changing parameters of the participant's avatar in the exergame. METHODOLOGY: An experimental design was used with 89 female undergraduate students (Mean age=18.74+1.05, 18 to 21 years) who were randomly assigned to the high task demand condition (avatar weight remaining constant) or low task demand condition (avatar losing weight). Prior to the biking task, the Exercise Self-Efficacy scale was used to measure ESE. Participants biked on a stationary bike while immersed in a virtual environment with an avatar and were told the avatar would slim if they cycled fast enough. Only half of participants' avatars actually slimmed (high task demand manipulation). During biking, cardiovascular measures were assessed using a Biopac MP150 system with an Impedance Cardiograph and CNAP Monitor 500. One week after completion of the study, participants reported amount of exercise completed in the last week (in 15 minute increments) via the Physical Activity Questionnaire. Moderated regressions and moderated mediation models were used to examine the interaction of ESE levels, experimental condition and cardiovascular reactivity on amount of strenuous physical activity. RESULTS: Individuals with high ESE showed similar results in both task demand conditions with physiological reactivity patterns indicative of threat. Individuals with low ESE with a static avatar completed less exercise than those with low ESE with a slimming avatar. CONCLUSION: Results confirm that individuals with low ESE are particularly vulnerable to exercise demands.
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Dixit, Abhinav, Yogendra Raj Singh, Prasenjit Mitra, and Praveen Sharma. "Smoking induced alterations in auditory pathways: Evidence from evoked potentials." Indian Journal of Physiology and Pharmacology 64 (July 31, 2020): 118–22. http://dx.doi.org/10.25259/ijpp_104_2020.

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Objectives: Auditory Brainstem Responses (ABR) are used for assessment of integrity of auditory pathway. Given the widespread prevalence of smoking, interpretation of ABR data must be done in light of smoker/nonsmoker status. Materials and Methods: The present study was done on 30 normal, healthy non-smoker males and 30 healthy, smoker males in the age group of 18-40 years. Approval of Institutional Ethics Committee and written informed consent was taken from all volunteers. ABR was recorded using Biopac MP 150 system. The recordings were done in a state of abstinence of 12 hours (chronic smoking state) and 10 minutes after smoking (acute smoking state). In the non-smoker group, only one set of recordings were done. The peak latencies and amplitudes of the ABR waves were analyzed. Results: Analysis of data revealed a significant prolongation of the latencies of wave I and II and Inter-peak latency I-III in chronic smoking state as compared to non-smoking state. The amplitudes of waves I, II and V were also significantly reduced in chronic smoking state. A comparison between the non-smokers and acute smoking state revealed significantly prolonged latency of waves I and II in the acute smoking state accompanied by a significant decrease in the amplitudes of all waves of ABR. There were no significant differences in latencies and amplitudes of the chronic and acute smoking state. Conclusion: Smoking led to an increase in latency and decrease in amplitude, thereby indicating that it adversely affected the auditory pathway. Thus, interpretation of data of ABR should consider smoking as a confounding variable.
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Peresypkina, Anna A. "A comparative evaluation of the efficacy of dimethylaminoethanol derivative 7–16, C7070 and picamilon in correction of experimental hypertensive neuroretinopathy." Research Results in Pharmacology 4, no. 3 (October 22, 2018): 1–8. http://dx.doi.org/10.3897/rrpharmacology.4.29388.

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Introduction. The efficacy of dimethylaminoethanol (DMAE) derivative 7–16, substance C7070 in comparison with picamylon in hypertensive neuroretinopathy model in white laboratory rats was evaluated. Materials and methods. For measuring the blood pressure, a system of noninvasive blood pressure measurement in small animals NIBP200 was used. Ophthalmoscopy was performed by using Bx a Neitz ophthalmoscope (Japan) and Osher MaxField 78D lens, OI-78M model. Electroretinography (ERG) was recorded in response to a single stimulation. Biopotentials were presented graphically on the screen with the help of BIOPAC SYSTEMS MP-150 with ACQKNOWLEDGE 4.2 software (USA). To assess a degree of a functional retinal disorder, the b/a coefficient was used. Results and discussion. The most pronounced protective effect on the model of hypertensive neuroretinopathy is demonstrated by C7070, which is expressed in the notable approximation to the normal eye fundus image and reaching the target values of the b/a coefficient. In the group with correction by DMAE derivative 7–16, a protective effect is observed, which exceeds picamilon, which is expressed in the elimination of soft and solid exudates, vein and venule plethora, vascular tortuosity, arterial spasm, Salus-Gunn I symptom, hemorrhages; the b/a increases significantly by 26% compared to the group without correction (p &lt; 0.05). Conclusion. The eye fundus image and functional state of the retina are completely restored when correcting experimental hypertensive neuroretinopathy with C7070 in a dose of 50 mg/kg to laboratory rats and partially restored when correcting with DMAE derivative 7–16 in a dose of 25 mg/kg, which in both cases exceeds the protective effect of the reference drug picamilon on the model of hypertensive neuroretinopathy.
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44

Price, Ffion G., JohnEric W. Smith, Alana J. Turner, Ben M. Krings, Hunter S. Waldman, Harish Chander, Adam C. Knight, and Matthew J. McAllister. "High-Intensity Interval Training in Middle-Distance NCAA Division I 800/1500m Collegiate Athletes." International Journal of Kinesiology and Sports Science 8, no. 3 (July 31, 2020): 28. http://dx.doi.org/10.7575/aiac.ijkss.v.8n.3p.28.

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Background: High-intensity interval training (HIIT) has grown in popularity, with studies demonstrating improvements in aerobic and anaerobic performances within Sedentary and Recreationally active adults. Little research has been comprised on collegiate, middle-distance runners (800m/1500m). Objective: This research study aimed to investigate the impact of four-weeks HIIT cycling training on collegiate 800/1500m runners performance, and determine whether HIIT can be used as an alternative training method for student athletes. Methods: Twelve middle-distance runners were recruited, with six athletes completing the intervention. Athletes completed pre-testing, which included a 1500m time trial, a GXT, stride length and frequency measurements, and MVIC, using Biopac electromyography (EMG). After pre-testing, athletes completed four weeks of HIIT twice per week. The HIIT consisted of four 20-second bouts with 4 minutes recovery. Following the completion of the training intervention, post-testing was performed for all measures. A paired t-test was used to determine differences between pre- and post-performance tests. An ANOVA was used to determine changes in heart rate and RPE during the GXT. Results: Significant changes were demonstrated between the pre- and post-muscle activation tests of the quadriceps (p=0.05). Significant changes were seen with both HR (p<0.05) and RPE (p<0.05) throughout the GXT. No other significant differences were demonstrated between pre- and post-performance tests, concluding four-weeks HIIT does not alter 800/1500m performance. Conclusion: From the results of this study, HIIT could be used as an alternate method for training for 800/1500m runners. Further reasearch should be conducted toto further understand the impacts of HIIT on middle distance athletes.
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45

Carvalho, Helena, and Crystal A. West. "Voluntary participation in an active learning exercise leads to a better understanding of physiology." Advances in Physiology Education 35, no. 1 (March 2011): 53–58. http://dx.doi.org/10.1152/advan.00011.2010.

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Students learn best when they are focused and thinking about the subject at hand. To teach physiology, we must offer opportunities for students to actively participate in class. This approach aids in focusing their attention on the topic and thus generating genuine interest in the mechanisms involved. This study was conducted to determine if offering voluntary active learning exercises would improve student understanding and application of the material covered. To compare performance, an anonymous cardiorespiratory evaluation was distributed to two groups of students during the fall (control, n = 168) and spring (treatment, n = 176) semesters. Students in both groups were taught by traditional methods, and students in the treatment group had the option to voluntary participate in two additional active learning exercises: 1) a small group discussion, where students would discuss a physiology topic with their Teaching Assistant before running BIOPAC software for the laboratory exercise and 2) a free response question, where students anonymously responded to one short essay question after the laboratory exercise. In these formative assessments, students received feedback about their present state of learning from the discussion with their peers and also from the instructor comments regarding perceived misconceptions. As a result of the participation in these activities, students in the treatment group had a better overall performance [ χ2 (degree of freedom = 1) = 31.2, P < 0.001] on the evaluation (treatment group: 62% of responses correct and control group: 49%) with an observed difference of 13% (95% confidence interval: 8, 17). In conclusion, this study presents sufficient evidence that when the opportunity presents itself, students become active participants in the learning process, which translates into an improvement in their understanding and application of physiological concepts.
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46

Плотников, М. Б., О. И. Алиев, А. В. Сидехменова, А. Ю. Шаманаев, and А. М. Анищенко. "Effects of dihydroquercetin on blood pressure and hemorheological parameters in SHR rat during early and stable arterial hypertension." ZHurnal «Patologicheskaia fiziologiia i eksperimental`naia terapiia», no. 3() (September 16, 2020): 126–30. http://dx.doi.org/10.25557/0031-2991.2020.03.126-130.

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Согласно современным представлениям, важную роль в прогрессировании артериальной гипертензии (АГ) играет изменение реологических свойств крови. К настоящему времени опубликованы работы, в которых показано улучшение гемореологических параметров за счет использования различных лекарственных средств при сердечно-сосудистых заболеваниях. Цель работы - исследование влияния дигидрокверцетина (ДГК) на артериальное давление (АД) и гемореологические параметры у крыс линии SHR в различные периоды развития АГ. Методика. Эксперименты проведены на крысах со спонтанной гипертензией (spontaneously hypertensive rats, SHR) двух возрастных групп: период развития АГ (возраст крыс SHR на начало эксперимента 5 нед) и период стабильной АГ (возраст крыс SHR на начало эксперимента 11 нед). ДГК (50 мг/кг) вводили внутрижелудочно в течение 6 нед. Крысы контрольных групп получали эквиобъемное количество крахмальной слизи по той же схеме. АД у бодрствующих крыс регистрировали неинвазивным методом (NIBP200A, «Biopac Systems, Inc.», США). Вязкость цельной крови, стабилизированной ЭДТА (в диапазоне скоростей сдвига 15-450 с-1), и плазмы (450 с-1) измеряли на ротационном вискозиметре (LVDV-II+ Pro, CP40, «Brookfield Engineering Labs Inc.») при 36 оС. Гематокрит определяли методом центрифугирования. Агрегацию и деформируемость эритроцитов исследовали на анализаторе «RheoScan-AnD 300» («Rheo Meditech, Inc.»). Результаты. У крыс SHR после 6-недельного введения ДГК в период развития АГ не наблюдалось значимых различий уровня систолического АД (САД), макро- и микрореологических показателей по сравнению с параметрами в контрольной группе. У крыс SHR со стабильной АГ введение ДГК приводило к снижению САД, ослаблению агрегации эритроцитов с увеличением их индекса элонгации и снижению вязкости крови по сравнению с контрольной группой. Заключение. Нарушение гемореологических параметров крови выражено значимо меньше у крыс SHR в начальной стадии формирования АГ. Использование ДГК в период развития АГ не оказывало статистически значимого влияния на АД. В период стабильной АГ гипотензивное действие ДГК связано в том числе с его способностью снижать вязкость крови и улучшать такие микрореологические параметры, как агрегация и деформируемость. Arterial hypertension (AH) is the most common cardiovascular disease and a risk factor for other vascular diseases and organ damage. According to current concepts, changes in blood rheology play an important role in AH progression. Drugs improving hemorheological parameters have been shown to be beneficial in cardiovascular diseases. Aim. To study the effect of dihydroquercetin (DHQ) on blood pressure (BP) and hemorheological parameters in spontaneously hypertensive rats (SHR) at different stages of AH. Methods. Experiments were performed on SHR in the period of AH development (5-week-old SHR at the beginning of experiments) and in the period of stable AH (11-week-old SHR at the beginning of experiments). DHQ (50 mg/kg) was administered intragastrically for 6 weeks. Rats of the control groups received an equal volume of starch mucilage according to the same schedule. BP was measured with a non-invasive NIBP200A (Biopac Systems, Inc., USA) instrument in conscious rats. Viscosity of K2EDTA-stabilized whole blood (shear rate range, 15-450 s-1) and plasma (450 s-1) was measured with a rotational viscometer (LVDV-II + Pro, CP40, Brookfield Engineering Labs Inc.) at 36 °C. Hematocrit was determined by centrifugation. Aggregation and deformability of red blood cells was studied with a RheoScan-AnD 300 analyzer (RheoMeditech, Inc.). Results. After 6 weeks of DHQ administration in the period of AH development, mean blood pressure (MBP) and macro- and microrheological parameters did not significantly differ from the respective values in the control group In SHR with stable AH, the DHQ treatment resulted in decreased MBP, blood viscosity, and red blood cell aggregation and increased red blood cell elongation index compared to the control group. Conclusion. Disorders of hemorheological parameters were significantly less pronounced in SHR with early AH. Perhaps for this reason, the DHQ treatment during the development of hypertension did not exert a significant effect on BP. In the period of stable hypertension, hyperviscosity syndrome progressed in SHR. The antihypertensive effect of DHQ in this period, among other things, was associated with a beneficial effect on micro-rheological parameters, including red blood cell aggregation and deformability, which was evident as decreased blood viscosity.
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47

Bell, Alana. "Biopic Bibliography." Biography 23, no. 1 (2000): 212–22. http://dx.doi.org/10.1353/bio.1999.0002.

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48

Shostak, Stanley. "Desmond'sHuxley:The Biopic." European Legacy 4, no. 5 (October 1999): 113–15. http://dx.doi.org/10.1080/10848779908580002.

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49

Buszman, Piotr, Przemek Nowakowski, Krzysztof Milewski, Bartlomiej Orlik, Aleksander Zurakowski, Tomasz Ludyga, Marcin Debinski, et al. "TCT-563 Prospective, controlled, clinical randomized trial evaluating novel, microcrystalline and biodegradable polymer paclitaxel coated balloon for the treatment of femoro-popliteal disease (The BIOPAC trial) - one year outcome." Journal of the American College of Cardiology 70, no. 18 (October 2017): B233. http://dx.doi.org/10.1016/j.jacc.2017.09.741.

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50

Schultz, Nicolai Aagaard, Christian Dehlendorff, Benny Vittrup Jensen, Jon K. Bjerregaard, Kaspar Nielsen, Stig Egil Bojesen, Dan Calatayud, et al. "MicroRNA biomarkers in whole blood for detection of pancreatic cancer." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 4052. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.4052.

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4052 Background: There is a great need for biomarkers for early diagnosis of patients with pancreatic cancer (PC) to improve their poor prognosis. The aims were (1) to describe differences in miRNA expression in whole blood between patients with PC, healthy subjects (HS) and patients with chronic pancreatitis (CP); and (2) to identify panels of miRNAs for early diagnosis of PC. Methods: Case-control study. 409 patients with PC, 33 patients with other periampullary cancers (PAC) and 25 patients with CP were included prospectively in the Danish BIOPAC biomarker study. 312 blood donors were included as HS. MiRNA expressions in pretreatment 2.5 ml whole blood samples collected in PAXgene RNA tubes were investigated in three independent cohorts: “Discovery Study” (PC n=143, CP n=18, HS n=69); “Training Study” (PC n=180, HS n=199); and “Validation Study” (PC n=86, PAC n=33, CP n=7, HS n=44). TaqMan Human MicroRNA assay was used to screen 754 miRNAs in the “Discovery Study”. Fluidigm BioMark PCR System was used in the “Training Study” (38 miRNAs) and “Validation Study” (13 miRNAs). Results: The “Discovery Study” demonstrated that 38 miRNAs (out of a total of 754 miRNAs) in whole blood were significantly deregulated between patients with PC and controls. These miRNAs were tested in the “Training Study” and two diagnostic indexes were constructed including 4 miRNAs in bPANmiRC index I (= miR-150 + miR-636 – miR-145 – miR-223) or 10 miRNAs in bPANmiRC index II (= 6.9275 – 0.2134xmiR-122 – 0.3560xmiR-34a – 0.8577xmiR-145 + 1.0043xmiR-636 – 0.6725xmiR-223 + 0.7018xmiR-26b – 0.3233xmiR-885.5p + 1.1304xmiR-150 – 0.2204xmiR-126* - 0.1730xmiR-505) (AUC 0.86/0.93, sensitivity 85%/85% and specificity 64%/85%). Conclusions: We identified two diagnostic indexes, using 4 or 10 miRNAs in peripheral whole blood, with a potential clinical value in the evaluation of patients with uncharacteristic symptoms to identify PC at an early stage.
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