Academic literature on the topic 'Biopharmaceutics'

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Journal articles on the topic "Biopharmaceutics"

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Cvijic, Sandra, Svetlana Ibric, and Jelena Parojcic. "Integrated biopharmaceutical approach in pharmaceutical development and drug characterization: General concept and application." Chemical Industry 74, no. 6 (2020): 389–97. http://dx.doi.org/10.2298/hemind210104002c.

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The importance of biopharmaceutical considerations in pharmaceutical development and drug characterization has been well recognized both by pharmaceutical industry and regulatory authorities as a tool to establish predictive relationships between drug product quality attributes (in vitro data) and its clinical performance (in vivo data). In the present paper, contemporary biopharmaceutics toolkit including in vivo predictive dissolution testing, Biopharmaceutics Classification System, physiologically based pharmacokinetic and biopharmaceutics modeling and simulation, in vitro-in vivo correlati
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Huang, Ziyi, Xinyu Li, Yakun Sun, et al. "Enhancing the Electrochemical Properties and Processing Techniques of Carbon Nanotubes for Bio pharmacological Applications: A Research Perspective." Highlights in Science, Engineering and Technology 58 (July 12, 2023): 297–303. http://dx.doi.org/10.54097/hset.v58i.10111.

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Compared with other biopharmaceutical technologies, carbon nanotubes not only have unique structure, but also have strong electrochemical properties, which occupy an important position in the fields of chemistry, physics, biopharmaceutics and materials science, and have played an active role in promoting the development of biopharmaceutics and chemical industry in China. Carbon nanotubes (CNTs) are mainly used in the field of biopharmacology for the determination of small biological molecules and drug molecules, the determination of dopamine and thrombin, the determination of high concentratio
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Silva, Daniela Amaral, M. Kenneth Cor, Afaseneh Lavasanifar, Neal M. Davies, and Raimar Löbenberg. "Using GastroPlus to teach complex biopharmaceutical concepts." Pharmacy Education 22, no. 1 (2022): 336–47. http://dx.doi.org/10.46542/pe.2022.221.336347.

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Context: In response to the COVID-19 pandemic, many educational adjustments had to be made to move in-person teaching to online classrooms. This report showcases the use of the software GastroPlus in an undergraduate-level pharmacy course. Programme description: This course aimed for the students to learn how to perform a mechanistically based simulation to predict the oral absorption pattern, pharmacokinetics, and biopharmaceutics properties of compounds in humans. The computer simulation offered the opportunity to teach concepts about bioavailability providing all kinds of experience with ma
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Chavda, HV, CN Patel, and IS Anand. "Biopharmaceutics classification system." Systematic Reviews in Pharmacy 1, no. 1 (2010): 62. http://dx.doi.org/10.4103/0975-8453.59514.

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Paixão, Paulo, Zvonimir Petric, and José A. G. Morais. "Physiologically Based Biopharmaceutics Model of Apixaban for Biopharmaceutics Risk Assessment." Pharmaceutics 17, no. 3 (2025): 382. https://doi.org/10.3390/pharmaceutics17030382.

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Background/Objectives: This study applies a Physiologically Based Biopharmaceutics Modeling (PBBM) framework to predict the bioavailability (BA) and bioequivalence (BE) of apixaban, a borderline BCS Class III/IV drug. It investigates how formulation factors, such as particle size, granulation method, and dissolution conditions, affect apixaban’s in vivo behavior under fasting conditions. Methods: A PBBM approach was developed by integrating physicochemical, formulation, and drug-related parameters to simulate dissolution and absorption using a middle-out strategy for combining in silico, in vi
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Idkaidek, Nasir M. "Interplay of biopharmaceutics, biopharmaceutics drug disposition and salivary excretion classification systems." Saudi Pharmaceutical Journal 22, no. 1 (2014): 79–81. http://dx.doi.org/10.1016/j.jsps.2013.02.002.

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Srinivas, NuggehallyR. "Biopharmaceutics, formulations and exposure." Asian Journal of Pharmaceutics 4, no. 1 (2010): 1. http://dx.doi.org/10.4103/0973-8398.63972.

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Bandaliyeva, A., S. Muslumzade, M. Aslanov, and A. Huseynova. "THE INFLUENCE OF THE PHARMACEUTİCAL FACTOR İN DOSAGE FORMS ON THE THERAPEUTİC EFFECTİVENESS OF DRUGS." Znanstvena misel journal, no. 99 (February 24, 2025): 47–49. https://doi.org/10.5281/zenodo.14919716.

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The primary goal of biopharmaceutics is to study significant pharmaceutical factors. Among these factors, the form in which drugs are prepared plays a crucial role in ensuring their high therapeutic effectiveness. From this perspective, studying these effects is currently one of the most important and relevant issues in the field of pharmaceutical technology. When considering dosage forms from a biopharmaceutical standpoint, it is necessary to apply new criteria for their classification. In this regard, classification based on the route of administration is more appropriate, as the method of a
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O'MULLANE, J. E., P. ARTURSSON, and E. TOMLINSON. "Biopharmaceutics of Microparticulate Drug Carriers." Annals of the New York Academy of Sciences 507, no. 1 Biological Ap (1987): 120–40. http://dx.doi.org/10.1111/j.1749-6632.1987.tb45796.x.

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Ivanov, V. T., and V. I. Deigin. "Evolution of Peptide Drug Biopharmaceutics." Russian Journal of Bioorganic Chemistry 49, no. 3 (2023): 422–34. http://dx.doi.org/10.1134/s1068162023030123.

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Dissertations / Theses on the topic "Biopharmaceutics"

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Aljayyoussi, Ghaith. "Dendrimer biopharmaceutics : toward active dendrimer-cannabinoid drugs." Thesis, Cardiff University, 2011. http://orca.cf.ac.uk/14220/.

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The ultimate aim of the work described in this thesis was to (1) utilise PAMAM dendrimers as a tool to achieve differential transport across the intestinal mucosa and the blood brain barrier, where these dendrimers can be used to achieve oral bioavailability but avoid BBB penetration and CNS access and (2) to create cannabinoid-dendrimer conjugates that are active in their own right and whose penetration to the brain is prevented but whose intestinal activity is afforded for the treatment of IBD. Overall, the work described in this thesis has promoted a strategy whereby an active polymer (dend
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Skinner, Michael Fredrick. "Biopharmaceutics and pharmacokinetics of the macrolide antibiotic Josamycin." Thesis, Rhodes University, 1992. http://hdl.handle.net/10962/d1003269.

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The investigations detailed herein have been conducted to address various aspects of the biopharmaceutics and pharmacokinetics of josamycin which to-date, have received little or no attention in the literature. Areas of investigation have included the selective determination of josamycin in serum and urine samples, the stability of josamycin in stored biological samples, intrinsic dissolution rates, solubility, acid and alkali stability and bioavailability and pharmacokinetics after dosing with a solution, powder and tablets. High performance liquid chromatography (HPLC) was used as the main a
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Walton, Carol Julie. "Stakeholder influences on the commercialisation and delivery of cell-based medicinal products." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648388.

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Lindenberg, Marc. "A biopharmaceutics classification scheme for the development of new drugs." Aachen Shaker, 2007. http://d-nb.info/987761897/04.

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Lindenberg, Marc. "A biopharmaceutics classification scheme for the development of new drugs /." Aachen : Shaker, 2008. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016726181&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Faragalla, Jane Eliza. "Development of isoflavonoid-derived anti-prostatic cancer agents." Access electronically, 2005. http://www.library.uow.edu.au/adt-NWU/public/adt-NWU20060516.121728/index.html.

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Terespolsky, Susan Ann. "A study of the biopharmaceutics and pharmacokinetics of the macrolide antibiotic, erythromycin." Thesis, Rhodes University, 1992. http://hdl.handle.net/10962/d1003273.

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Erythromycin, a macrolide antibiotic isolated from Streptomyces erythreus, was first introduced into clinical medicine in 1952. It is active against most gram-positive bacteria, some gram-negative bacteria and is currently the agent of choice for Legionella pneumophila. Erythromycin is an acid-labile compound rapidly degrading in acidic solutions such as the acid environment of the stomach. As such, erythromycin absorption following oral administration of solid dosage forms is relatively poor. Accordingly there have been various approaches used to protect the drug against gastric inactivation.
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Lindenberg, Marc [Verfasser]. "A biopharmaceutics classification scheme for the development of new drugs / Marc Lindenberg." Aachen : Shaker, 2008. http://d-nb.info/116434238X/34.

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ARORA, DEEPIKA. "IN VITRO MODELS FOR INHALED CORTICOSTEROID (ICS) AEROSOLS: A STUDY OF THEIR BIOPHARMACEUTICS AND PHARMACOLOGY." VCU Scholars Compass, 2008. http://scholarscompass.vcu.edu/etd/1650.

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Lung cellular disposition and anti-inflammatory pharmacology of inhaled corticosteroids (ICSs) is complex, comprised of a cascade of aerosol deposition and dissolution, followed by cellular uptake for local pharmacological action. This project hypothesized that the kinetics of dissolution for certain ICS aerosols generated from inhaler products were kinetically rate-determined for their cellular uptake and local pharmacological action. A novel dissolution testing system was developed to determine the dissolution kinetics for the ICS aerosols. A total of 5 ICSs aerosols generated from 6 inhale
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Arora, Deepika. "In vitro models for inhaled corticosteroid (ICS) aerosols : a study of their biopharmaceutics and pharmacology /." Not available unti 12/11/2013, 2008. http://hdl.handle.net/10156/2340.

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Books on the topic "Biopharmaceutics"

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Yu, Andrew B. C., 1945-, ed. Applied biopharmaceutics & pharmacokinetics. 4th ed. Appleton & Lange, 1999.

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Sugano, Kiyohiko. Biopharmaceutics Modeling and Simulations. John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118354339.

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Paul, Mossillo, and Pinzini John, eds. Biopharmaceutics and drug hypersensitivity. Nova Science Publishers, 2009.

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Shargel, Leon. Applied biopharmaceutics and pharmacokinetics. 3rd ed. Appleton & Lange, 1993.

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Yu, Andrew B. C., 1945-, ed. Applied biopharmaceutics and pharmacokinetics. 2nd ed. Appleton-Century-Crofts, 1985.

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Krishna, Rajesh, and Lawrence Yu, eds. Biopharmaceutics Applications in Drug Development. Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-72379-2.

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1954-, Edman Peter, ed. Biopharmaceutics of ocular drug delivery. CRC Press, 1993.

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Macheras, P. Biopharmaceutics of orally administered drugs. E. Horwood, 1994.

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Macheras, P. Biopharmaceutics of orally administered drugs. Ellis Horwood, 1995.

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Barry, Thomas G. Quality systems in regulated biopharmaceutical manufacturing environments. University College Dublin, 1992.

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Book chapters on the topic "Biopharmaceutics"

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Frijlink, Erik, Daan Touw, and Herman Woerdenbag. "Biopharmaceutics." In Practical Pharmaceutics. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-15814-3_16.

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Frijlink, Henderik, Frederic Lagarce, Daan Touw, and Herman Woerdenbag. "Biopharmaceutics." In Practical Pharmaceutics. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-20298-8_5.

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Frömming, Karl-Heinz, and József Szejtli. "Pharmacokinetics and Biopharmaceutics." In Topics in Inclusion Science. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-015-8277-3_6.

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Quiroga, Pablo A. M. "Biopharmaceutics Classification System." In The ADME Encyclopedia. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-84860-6_137.

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Talevi, Alan, and Pablo A. M. Quiroga. "Introduction. Biopharmaceutics and Pharmacokinetics." In ADME Processes in Pharmaceutical Sciences. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-99593-9_1.

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Andrews, Laura P., and James D. Green. "Unique Considerations for Biopharmaceutics." In Early Drug Development. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470613191.ch12.

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Talevi, Alan, and Pablo A. Quiroga. "Introduction: Biopharmaceutics and Pharmacokinetics." In ADME Processes in Pharmaceutical Sciences. Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-50419-8_1.

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Ghosh, Subhrojyoti, Varshaa Arer, and Debasish Kar. "Antibiotic Pharmacology and Biopharmaceutics." In Antibiotics and Their Mechanisms of Action. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-6851-6_14.

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Sutton, Steven C. "Biopharmaceutics and Veterinary Drug Delivery." In Advances in Delivery Science and Technology. Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-4439-8_6.

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Uppoor, Ramana S., Jayabharathi Vaidyanathan, Mehul Mehta, and Lawrence X. Yu. "Biowaiver and Biopharmaceutics Classification System." In FDA Bioequivalence Standards. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1252-0_5.

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Conference papers on the topic "Biopharmaceutics"

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Bakeev, Katherine, Jacopo Zini, Amutha Daniel, and Mari Tenhunen. "Time-Gated Raman for Bioprocess Analysis." In Applied Industrial Spectroscopy. Optica Publishing Group, 2024. https://doi.org/10.1364/ais.2024.am1a.2.

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Raman spectroscopy for process monitoring can be limited due to interference of sample-induced fluorescence overwhelming the Raman signal. Using a Timegated<sup>®</sup> Raman spectrometer overcomes fluorescence and we show the successful monitoring of biopharmaceutical product production. Full-text article not available; see video presentation
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BAKHSHANDEH, BEHNAZ, and ZARVAN SHAHRZAD. "THE FUTURE OF BIOPHARMACEUTICS' PRODUCTION." In Proceedings of the International Conference on CBEE 2009. WORLD SCIENTIFIC, 2009. http://dx.doi.org/10.1142/9789814295048_0001.

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Pham-The, Hai, Huong Le-Thi-Thu, Teresa Garrigues, Marival Bermejo, Isabel González-Álvarez, and Miguel Cabrera-Pérez. "Towards computational prediction of Biopharmaceutics Classification System: a QSPR approach." In MOL2NET, International Conference on Multidisciplinary Sciences. MDPI, 2015. http://dx.doi.org/10.3390/mol2net-1-b008.

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Sanchez-Lopez, Angelica Lizeth, Eduardo F. Perez de Lara-Gonzalez, Hector Franco-Villareal, and Yocanxochitl Perfecto-Avalos. "Design and conduct of clinical research: Raising awareness of ethical aspects in biopharmaceutics for students of Biotechnology Engineering." In 2021 IEEE Global Engineering Education Conference (EDUCON). IEEE, 2021. http://dx.doi.org/10.1109/educon46332.2021.9453988.

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Khalikov, S. S. "FEATURES OF MECHANOCHEMICAL TECHNOLOGY IN THE DEVELOPMENT OF PARASITOCIDES." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV”, 2023. http://dx.doi.org/10.31016/978-5-6048555-6-0.2023.24.498-502.

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The purpose of the research is to study the features of the mechanochemical
 modification of medicinal substances with low solubility in water. According to
 the Biopharmaceutics Classification System, about 6% of medicinal substances
 belong to the group of insoluble medicinal substances, and about 47%, to practically
 insoluble medicinal substances, i.e. more than a half substances have problems with
 solubility, and therefore bioavailability and pharmacological activity. To achieve
 the therapeutic effect of such substances, it is necessary to deliberately incr
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Vlada, Marin. "NONLINEAR MODELS. THEORY, SOFTWARE AND APPLICATIONS." In eLSE 2013. Carol I National Defence University Publishing House, 2013. http://dx.doi.org/10.12753/2066-026x-13-188.

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This paper presents mathematical models that estimate nonlinear evolution processes or phenomena based on parameters that define processes and phenomena in pursuit of calculations and approximations (fitting) of experimental data. It addresses the non-linear model (nonlinear regression), the method of Least Squares (MLS) with examples. Are presented theoretical calculations for logarithmic and exponential models realizing a comparison with results obtained using software. In practice in various scientific, economic, social, etc.. occur most complex problems to be solved. Science and scientific
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Jelisic, Elena, Nenad Ivezic, Boonserm Kulvatunyou, Perawit Charoenwut, and Ana Nikolov. "An Investigation Into an Approach for Automated Supply Chain Onboarding." In ASME 2023 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2023. http://dx.doi.org/10.1115/detc2023-117486.

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Abstract The COVID-19 pandemic has brought the cold chain for biopharmaceutical products to the spotlight. To preserve their structure and function, biopharmaceuticals such as cells, proteins and enzymes, RNA molecules, and RNA-based drugs (e.g., mRNA-based COVID-19 vaccines) require low temperatures for proper handling, storage, and transport. Due to the sensitivity of these products transported through cold chains and the lack of traceability, risks associated with the stability, efficacy, safety, tardiness, quality, and waste are significant. For this reason, the ability to quickly find, co
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Hannappel, Margarete. "Biopharmaceuticals: From peptide to drug." In STRUCTURE, FUNCTION AND DYNAMICS FROM NM TO GM: Proceedings of the 8th Jagna International Workshop. Author(s), 2017. http://dx.doi.org/10.1063/1.4996533.

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Skachilova, Sofia, and Ekaterina Simakina. "NEUROMEDIATOR AMINO ACIDS. BIOPHARMACEUTICAL ASPECTS." In XX INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2024. http://dx.doi.org/10.29003/m4020.sudak.ns2024-20/253-254.

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Rao, Xinyi. "Value Analysis of Biopharmaceutical Industry Investment." In 2022 2nd International Conference on Enterprise Management and Economic Development (ICEMED 2022). Atlantis Press, 2022. http://dx.doi.org/10.2991/aebmr.k.220603.062.

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Reports on the topic "Biopharmaceutics"

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Shrivastava, Rashmi. Proactive regulators key to safe biopharmaceuticals. Edited by Charis Palmer. Monash University, 2022. http://dx.doi.org/10.54377/250c-53b7.

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Frakes, Michael, and Melissa Wasserman. Strategic Patenting: Evidence from the Biopharmaceutical Industry. National Bureau of Economic Research, 2025. https://doi.org/10.3386/w34024.

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Devine, Joshua W. Follow-On Biologic Competition in the Biopharmaceutical Marketplace". Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada431410.

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Wong, Paul, Andre Walker, Marcus Boyer, et al. CPV of legacy products in the biopharmaceutical industry. BioPhorum, 2018. http://dx.doi.org/10.46220/2018ds001.

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Deutschmann, Sven, Margit Franz-Riethdorf, and Bela Green. TR Alternative adventititous agents detection methods in biopharmaceuticals. BioPhorum, 2022. http://dx.doi.org/10.46220/2022tr003.

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Lehr, Briana, and Jon Wannlund. Trace element variation of soy hydrolysate used in biopharmaceutical manufacturing. BioPhorum, 2020. http://dx.doi.org/10.46220/2020ds005.

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Fang, Chin. Boost the biopharmaceutical industry’s research efficiency with hyperscale data distribution. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1651183.

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Trusheim, Mark, Murray Aitken, and Ernst Berndt. Characterizing Markets for Biopharmaceutical Innovations: Do Biologics Differ from Small Molecules? National Bureau of Economic Research, 2010. http://dx.doi.org/10.3386/w16014.

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Abramovsky, Laura. Global engagement in R&D: a portrait of biopharmaceutical patenting firms. Institute for Fiscal Studies, 2015. http://dx.doi.org/10.1920/wp.ifs.2015.1518.

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Vernooij, Eric, Valerie Rautureau, Atanas Koulov, Mitsutaka Shiraski, Alex Artau, and Scott Ewan. standardized methodology to support particle investigations and classification in biopharmaceutical parenteral products. BioPhorum, 2021. http://dx.doi.org/10.46220/2021ff006.

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