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Journal articles on the topic 'Bioprocess engineering'

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1

Galindo, E. "Bioprocess engineering." Trends in Biotechnology 16, no. 7 (July 1, 1998): 282–83. http://dx.doi.org/10.1016/s0167-7799(98)01211-6.

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2

Boudrant, Joseph, and Jack Legrand. "Bioprocess engineering." Process Biochemistry 45, no. 11 (November 2010): 1757. http://dx.doi.org/10.1016/j.procbio.2010.09.002.

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3

Villadsen, John. "“Bioprocess engineering”." Chemical Engineering Science 57, no. 7 (April 2002): 1235–36. http://dx.doi.org/10.1016/s0009-2509(02)00006-4.

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4

Lightfoot, E. N. "Bioprocess engineering." Chemical Engineering Science 50, no. 6 (March 1995): 1069. http://dx.doi.org/10.1016/0009-2509(95)90139-6.

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5

Jordan, M. A. "Bioprocess engineering principles." Minerals Engineering 9, no. 1 (January 1996): 133–35. http://dx.doi.org/10.1016/s0892-6875(96)90075-8.

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6

Chisti, Yusuf. "Bioprocess engineering for everyone…" Biotechnology Advances 31, no. 2 (March 2013): 357. http://dx.doi.org/10.1016/j.biotechadv.2012.12.007.

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7

Hu, Wei-Shou, and James C. Liao. "Biotechnology and bioprocess engineering." Current Opinion in Chemical Engineering 2, no. 4 (November 2013): 363–64. http://dx.doi.org/10.1016/j.coche.2013.10.004.

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8

Sch�gerl, K. "Makers of bioprocess engineering." Bioprocess Engineering 11, no. 4 (September 1994): 121. http://dx.doi.org/10.1007/bf00518732.

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9

PAZOS, Marta, Maria A. LONGO, and M. Angeles SANROMAN. "Experiences of Innovation Teaching in Bioprocess Engineering University Course." Revista Romaneasca pentru Educatie Multidimensionala 5, no. 1 (June 30, 2013): 123–39. http://dx.doi.org/10.18662/rrem/2013.0501.09.

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10

Chéruy, A. "Software sensors in bioprocess engineering." Journal of Biotechnology 52, no. 3 (January 1997): 193–99. http://dx.doi.org/10.1016/s0168-1656(96)01644-6.

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11

Panke, Sven, and Marcel G. Wubbolts. "Enzyme technology and bioprocess engineering." Current Opinion in Biotechnology 13, no. 2 (April 2002): 111–16. http://dx.doi.org/10.1016/s0958-1669(02)00302-6.

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12

Salomé, M. "Bioprocess engineering — the first generation." Biochimie 72, no. 4 (April 1990): 307–8. http://dx.doi.org/10.1016/0300-9084(90)90101-l.

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13

Hutchinson, U. F., N. P. Jolly, B. S. Chidi, M. Mewa Ngongang, and S. K. O. Ntwampe. "Vinegar Engineering: a Bioprocess Perspective." Food Engineering Reviews 11, no. 4 (July 29, 2019): 290–305. http://dx.doi.org/10.1007/s12393-019-09196-x.

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14

Schügerl, K. "Bioprocess engineering: the first generation." Chemical Engineering and Processing: Process Intensification 29, no. 1 (January 1991): 64. http://dx.doi.org/10.1016/0255-2701(91)87014-t.

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15

Noll, Philipp, Lars Lilge, Rudolf Hausmann, and Marius Henkel. "Modeling and Exploiting Microbial Temperature Response." Processes 8, no. 1 (January 17, 2020): 121. http://dx.doi.org/10.3390/pr8010121.

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Temperature is an important parameter in bioprocesses, influencing the structure and functionality of almost every biomolecule, as well as affecting metabolic reaction rates. In industrial biotechnology, the temperature is usually tightly controlled at an optimum value. Smart variation of the temperature to optimize the performance of a bioprocess brings about multiple complex and interconnected metabolic changes and is so far only rarely applied. Mathematical descriptions and models facilitate a reduction in complexity, as well as an understanding, of these interconnections. Starting in the 19th century with the “primal” temperature model of Svante Arrhenius, a variety of models have evolved over time to describe growth and enzymatic reaction rates as functions of temperature. Data-driven empirical approaches, as well as complex mechanistic models based on thermodynamic knowledge of biomolecular behavior at different temperatures, have been developed. Even though underlying biological mechanisms and mathematical models have been well-described, temperature as a control variable is only scarcely applied in bioprocess engineering, and as a conclusion, an exploitation strategy merging both in context has not yet been established. In this review, the most important models for physiological, biochemical, and physical properties governed by temperature are presented and discussed, along with application perspectives. As such, this review provides a toolset for future exploitation perspectives of temperature in bioprocess engineering.
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16

Lange, Julian, Ralf Takors, and Bastian Blombach. "Zero-growth bioprocesses: A challenge for microbial production strains and bioprocess engineering." Engineering in Life Sciences 17, no. 1 (November 11, 2016): 27–35. http://dx.doi.org/10.1002/elsc.201600108.

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17

Pilarek, Maciej. "Liquid Perfluorochemicals as Flexible and Efficient Gas Carriers Applied in Bioprocess Engineering: An Updated Overview and Future Prospects." Chemical and Process Engineering 35, no. 4 (December 1, 2014): 463–87. http://dx.doi.org/10.2478/cpe-2014-0035.

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Abstract Fully synthetic, biochemically inert and water-immiscible liquid perfluorochemicals (PFCs) are recognised as flexible liquid carriers/scavengers of gaseous compounds (respiratory gases mainly, i.e. O2 and CO2) and increasingly applied in bioprocess engineering. A range of unmatched physicochemical properties of liquid PFCs, i.e. outstanding chemo- and thermostability, extremely low surface tension, simultaneous hydro- and lipophobicity, which result from carbon chain substitution with fluorine atoms (the most electronegative chemical element) and the presence of intramolecular C-F bonds (the strongest single bond known in organic chemistry) have been described in detail. Exceptional propensity to solubility of respiratory gases in liquid perfluorinated compounds has been widely discussed. Advantages and disadvantages of bioprocess applications of liquid PFCs in the form of a pure PFC as well as in an emulsified form have been pointed out. A liquid PFC-mediated mass transfer intensification in various types of microbial, plant cell and animal cell culture systems: from miniaturised microlitre-scale cultures, via biomaterial-based scaffolds containing culture systems, to litre-scale bioreactors, has been reviewed and elaborated on bearing in mind the benefits of bioprocesses.
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18

KANG, KYUNG A. "Tissue Engineering as a Subdivision of Bioprocess Engineering." Annals of the New York Academy of Sciences 961, no. 1 (June 2002): 216–19. http://dx.doi.org/10.1111/j.1749-6632.2002.tb03088.x.

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19

Płaza, Grażyna, Varenyam Achal, and Deepika Kumari. "Microbiological Risk Assessment and Bioprocess Engineering." Multidisciplinary Aspects of Production Engineering 1, no. 1 (September 1, 2018): 233–39. http://dx.doi.org/10.2478/mape-2018-0030.

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Abstract The Europe 2020 strategy (European Commission, 2010) calls a bioeconomy as a key element for smart and green growth in Europe. The development of a greener and more resource-efficient economy gives rise to new technologies and materials, which in turn may result in increased exposure to biological agents or combinations of different potentially harmful factors. For example, the expanding recycling industry employs an increasing number of workers which have to face various health problems (pulmonary, gastrointestinal and skin problems) as a result of exposure to biological agents such as airborne microorganisms. However, specific numbers for occupational diseases in this sector are still lacking. There are various workplaces and professional activities especially from the green industry for which exposure to microbiological agents occur unexpectedly and in an uncontrolled way. The issue of uncontrolled microbial exposure there is for example in waste treatment and for retrofitting activities, both growing sectors of employment in a greening society. As a result of the problem in the green industrial sector, there is a need to develop tools for risk assessment and prevention measures. In order to be able to develop suitable risk management strategies, a further development of detection and identification methods for biological agents is needed to cover the whole spectrum of microorganisms. the present paper focuses on the microbiological risk assessment in the context of the development of new and safe industrial products and processes of green industry (bioindustry and bioprocessing).
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20

Sessink, O. D. T., H. van der Schaaf, H. H. Beeftink, R. J. M. Hartog, and J. Tramper. "Web-based education in bioprocess engineering." Trends in Biotechnology 25, no. 1 (January 2007): 16–23. http://dx.doi.org/10.1016/j.tibtech.2006.11.001.

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21

Zaborsky, Oskar R. "Bioprocess engineering: now and beyond 2000." FEMS Microbiology Reviews 16, no. 2-3 (February 1995): 277–85. http://dx.doi.org/10.1111/j.1574-6976.1995.tb00175.x.

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22

., Feng Chen, Yue Jiang ., and Fan Ouyang . "Development of Bioprocess Engineering in China." Biotechnology(Faisalabad) 4, no. 1 (December 15, 2004): 1–6. http://dx.doi.org/10.3923/biotech.2005.1.6.

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23

Krell, V., D. Jakobs-Schönwandt, and A. V. Patel. "Bioprocess Engineering to ImproveMetarhizium brunneumShelf Life." Chemie Ingenieur Technik 88, no. 9 (August 29, 2016): 1369. http://dx.doi.org/10.1002/cite.201650384.

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24

Show, Pau Loke, Kit Wayne Chew, and Jo-Shu Chang. "Special issue on algae bioprocess engineering." Bioengineered 11, no. 1 (January 1, 2020): 188. http://dx.doi.org/10.1080/21655979.2020.1729546.

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25

Scheper, Thomas. "Special issue on Micro-Bioprocess Engineering." Bioprocess and Biosystems Engineering 28, no. 2 (September 30, 2005): 73. http://dx.doi.org/10.1007/s00449-005-0019-y.

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26

Papoutsakis, Eleftherios Terry, and Nigel J. Titchener-Hooker. "Editorial overview: Biotechnology and bioprocess engineering." Current Opinion in Chemical Engineering 6 (November 2014): iv—vi. http://dx.doi.org/10.1016/j.coche.2014.10.002.

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27

Papoutsakis, Eleftherios Terry, and Nigel Titchener-Hooker. "Editorial overview: Biotechnology and bioprocess engineering." Current Opinion in Chemical Engineering 14 (November 2016): iv—v. http://dx.doi.org/10.1016/j.coche.2016.10.002.

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28

Titchener-Hooker, Nigel. "Editorial overview: Biotechnology and bioprocess engineering." Current Opinion in Chemical Engineering 18 (November 2017): i—ii. http://dx.doi.org/10.1016/j.coche.2017.11.004.

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29

Chaudhuri, J. B. "Bioprocess engineering: Systems, equipment and facilities." Chemical Engineering Journal and the Biochemical Engineering Journal 57, no. 1 (March 1995): 73–74. http://dx.doi.org/10.1016/0923-0467(95)80020-4.

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30

Ramkrishna, Doraiswami, and Jamey D. Young. "Editorial overview: Biotechnology and bioprocess engineering." Current Opinion in Chemical Engineering 32 (June 2021): 100686. http://dx.doi.org/10.1016/j.coche.2021.100686.

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31

Prado, R. C., and E. R. Borges. "MICROBIOREACTORS AS ENGINEERING TOOLS FOR BIOPROCESS DEVELOPMENT." Brazilian Journal of Chemical Engineering 35, no. 4 (December 2018): 1163–82. http://dx.doi.org/10.1590/0104-6632.20180354s20170433.

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32

Heinzelmann, Elsbeth. "Olten Meeting 2013 – Bioinformatics and Bioprocess Engineering." CHIMIA International Journal for Chemistry 68, no. 1 (February 26, 2014): 79–82. http://dx.doi.org/10.2533/chimia.2014.79.

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33

Osinga, R. "Marine bioprocess engineering: from ocean to industry." Trends in Biotechnology 17, no. 8 (August 1, 1999): 303–4. http://dx.doi.org/10.1016/s0167-7799(99)01323-2.

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34

Anesiadis, Nikolaos, William R. Cluett, and Radhakrishnan Mahadevan. "Dynamic metabolic engineering for increasing bioprocess productivity." Metabolic Engineering 10, no. 5 (September 2008): 255–66. http://dx.doi.org/10.1016/j.ymben.2008.06.004.

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35

Sarbatly, Rosalam, Awang Bono, Chu Chi Ming, Tham Heng Jin, Noor Maizura Ismail, and Zykamilia Kamin. "International Conference on Chemical and Bioprocess Engineering." IOP Conference Series: Earth and Environmental Science 36 (June 2016): 011001. http://dx.doi.org/10.1088/1755-1315/36/1/011001.

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36

Velayudhan, Ajoy. "Overview of integrated models for bioprocess engineering." Current Opinion in Chemical Engineering 6 (November 2014): 83–89. http://dx.doi.org/10.1016/j.coche.2014.09.007.

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37

Shimizu, Kazuyuki. "A tutorial review on bioprocess systems engineering." Computers & Chemical Engineering 20, no. 6-7 (June 1996): 915–41. http://dx.doi.org/10.1016/0098-1354(95)00188-3.

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38

Winterburn, James. "Editorial – bioprocess development." Biochemical Engineering Journal 151 (November 2019): 107361. http://dx.doi.org/10.1016/j.bej.2019.107361.

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39

Bohak, Zev. "Bioprocess Developments." Nature Biotechnology 3, no. 11 (November 1985): 1022. http://dx.doi.org/10.1038/nbt1185-1022.

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40

Kragl, Udo. "The Role of Reaction Engineering in Bioprocess Development." CHIMIA International Journal for Chemistry 74, no. 5 (May 27, 2020): 378–81. http://dx.doi.org/10.2533/chimia.2020.378.

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This short review highlights the role of reaction engineering as a tool for bioprocess development. Selected examples are discussed that demonstrate the need to understand thermodynamic and kinetic properties of the reaction system in order to identify potential bottlenecks. For coupled enzyme systems and reaction cascades modelling as well as selection of suitable reactor configurations is discussed. For the problem of overcoming product inhibition examples are given, followed by selected examples for in situ product removal. Finally, two reactor concepts for oxidation reactions requiring oxygen are briefly presented.
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41

Zaborsky, Oskar R. "Marine bioprocess engineering: the missing link to commercialization." Journal of Biotechnology 70, no. 1-3 (April 1999): 403–8. http://dx.doi.org/10.1016/s0168-1656(99)00093-0.

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42

Van Schaick Zillesen, Pleter G., Marcel H. Zwietering, and Klaas van 'T Riet. "Computer support of food and bioprocess engineering education." Computers & Education 21, no. 1-2 (July 1993): 89–94. http://dx.doi.org/10.1016/0360-1315(93)90051-j.

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43

Sessink, Olivier D. T., Hendrik H. Beeftink, Rob J. M. Hartog, and Johannes Tramper. "Virtual parameter-estimation experiments in Bioprocess-Engineering education." Bioprocess and Biosystems Engineering 28, no. 6 (January 13, 2006): 379–86. http://dx.doi.org/10.1007/s00449-005-0042-z.

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44

Kelly, Paul S., Colin Clarke, Martin Clynes, and Niall Barron. "Bioprocess engineering: micromanaging Chinese hamster ovary cell phenotypes." Pharmaceutical Bioprocessing 2, no. 4 (August 2014): 323–37. http://dx.doi.org/10.4155/pbp.14.28.

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45

K�ng, W., and A. Moser. "Bioprocess engineering characteristics of the horizontal stirred tank." Bioprocess Engineering 1, no. 1 (1986): 23–28. http://dx.doi.org/10.1007/bf00369461.

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46

Shimizu, Hiroshi. "Metabolic engineering — Integrating methodologies of molecular breeding and bioprocess systems engineering." Journal of Bioscience and Bioengineering 94, no. 6 (December 2002): 563–73. http://dx.doi.org/10.1016/s1389-1723(02)80196-7.

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47

Koutinas, Michalis, Alexandros Kiparissides, Efstratios N. Pistikopoulos, and Athanasios Mantalaris. "BIOPROCESS SYSTEMS ENGINEERING: TRANSFERRING TRADITIONAL PROCESS ENGINEERING PRINCIPLES TO INDUSTRIAL BIOTECHNOLOGY." Computational and Structural Biotechnology Journal 3, no. 4 (October 2012): e201210022. http://dx.doi.org/10.5936/csbj.201210022.

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48

SHIMIZU, HIROSHI. "Metabolic Engineering. Integrating Methodologies of Molecular Breeding and Bioprocess Systems Engineering." Journal of Bioscience and Bioengineering 94, no. 6 (2002): 563–73. http://dx.doi.org/10.1263/jbb.94.563.

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49

Knowle, R., A. Werner, and R. K. DeLong. "R4 Peptide-pDNA Nanoparticle Coated HepB Vaccine Microparticles: Sedimentation, Partitioning, and Spray Freeze Dry Bioprocesses." Journal of Nanoscience and Nanotechnology 6, no. 9 (September 1, 2006): 2783–89. http://dx.doi.org/10.1166/jnn.2006.427.

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Broad therapeutic application of nucleic acid micro- and nanoparticles will require bioprocesses capable of achieving high loads of structurally intact and functionality active DNA. Here we report condensation of pDNA into nanoparticles by sedimentation through R4 peptide and partitioning at a hydrophobic interface. ≥90% coating efficiency onto microparticles is achieved via this combined bioprocess with the pDNA retaining 85–90% intact supercoil after bioprocessing. SEM analyses of the microparticles produced therefrom reveals bound pDNA and R4 peptide nanoparticles. HPLC and chemical analyses afford quantification of the particle-associated pDNA and R4 peptide along with lactose, raffinose, or trehalose carbohydrate stabilizer, surface coatings uniformly applied by spray freeze-drying. Administration of these particles by gene gun demonstrates delivery to the nucleus of expressive nanoparticles and into rodents and pigs pronounced immunogenicity even after bioprocessing and accelerated degradation. These data support the discovery of a robust bioprocess platform for preparing macromolecule bound bioparticles with potential relevance beyond simple preparation of bioactive DNA vaccine.
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50

Zerajic, Stanko, Dragan Cvetkovic, and Ilija Mladenovic. "Modeling and simulation of the bioprocess with recirculation." Chemical Industry 61, no. 5 (2007): 263–71. http://dx.doi.org/10.2298/hemind0704263z.

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The bioprocess models with recirculation present an integration of the model of continuous bioreaction system and the model of separation system. The reaction bioprocess is integrated with separation the biomass, formed product, no consumed substrate or inhibitory substance. In this paper the simulation model of recirculation bioprocess was developed, which may be applied for increasing the biomass productivity and product biosynthesis increasing the conversion of a substrate-to-product, mixing efficiency and secondary C02 separation. The goal of the work is optimal bioprocess configuration, which is determined by simulation optimization. The optimal hemostat state was used as referent. Step-by-step simulation method is necessary because the initial bioprocess state is changing with recirculation in each step. The simulation experiment confirms that at the recirculation ratio a. = 0.275 and the concentration factor C = 4 the maximum glucose conversion to ethanol and at a dilution rate ten times larger.
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