Academic literature on the topic 'Bioreactor'

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Journal articles on the topic "Bioreactor"

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Feyereisen, Gary W., Ehsan Ghane, Todd W. Schumacher, Brent J. Dalzell, and M. R. Williams. "Can Woodchip Bioreactors Be Used at a Catchment Scale? Nitrate Performance and Sediment Considerations." Journal of the ASABE 66, no. 2 (2023): 367–79. http://dx.doi.org/10.13031/ja.15496.

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Highlights Novel three-bed, cascading-inlet bioreactor treated agricultural drainage from a 249-ha catchment. Nitrate removal rates and load reduction efficiencies were similar to those of traditional single-field bioreactors. Sedimentation problems reduced bed life; a sediment sensing and exclusion system solved them. This scale provides opportunities for centralized management and nutrient reduction verification. Abstract. Denitrifying bioreactors, a structural practice deployed at the field scale to meet water quality goals, have been underutilized and require additional evaluation at the s
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Reza, Víctor, Jorge A. Torres-Muñoz, and Jesús Guerrero. "Application of the ADRC Tunned with the Attractive Ellipsoid Approach for Continuous Bioreactors." Memorias del Congreso Nacional de Control Automático 7, no. 1 (2024): 375–80. https://doi.org/10.58571/cnca.amca.2024.064.

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The control of continuous bioreactors is essential for many bioprocesses. However, it is challenging to design and analyze controllers in a closed loop with a bioreactor due to the presence of uncertainties, external disturbances, and highly nonlinear and complex unknown dynamics. In this work, an active disturbance rejection controller is designed and analyzed for continuous bioreactors. For this task, the attractive ellipsoid approach is applied to analyze and tune the proposed controller based on an observer in a closed loop with the bioreactor’s nonlinear dynamic. Finally, the proposed alg
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Fitzpatrick, John J. "Insights from Mathematical Modelling into Energy Requirement and Process Design of Continuous and Batch Stirred Tank Aerobic Bioreactors." ChemEngineering 3, no. 3 (2019): 65. http://dx.doi.org/10.3390/chemengineering3030065.

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Bioreaction kinetics, oxygen transfer and energy modelling were applied to stirred tank aerobic bioreactors. This was done to investigate how key input design variables influence bioreactor size, feed and wasted substrate, and electrical energy requirements for aeration and cooling, and to compare batch and continuous modes of operation. Oxygen concentration in the liquid is a key input design variable, but its selection is challenging as it can result in design trade-offs. Reducing its value caused a decrease in electrical energy requirement, however this tended to increase the working volume
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Oktiawan, Wiharyanto, Irawan Wisnu Wardhana, Endro Sutrisno, Domuanri Gorat, and Alfian Rizky Rizaldianto. "Municipal Solid Waste Management Using Bioreactor Landfill in the Treatment of Organic Waste from Jatibarang Landfill, Semarang-Indonesia." E3S Web of Conferences 125 (2019): 07002. http://dx.doi.org/10.1051/e3sconf/201912507002.

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Landfilling is one of the easiest methods to be applied in the management of municipal solid waste (MSW). In its development, bioreactor landfill methods that have various advantages over conventional landfill emerge. This experiment aims to study the use of bioreactor landfills for the management of organic waste in Jatibarang Landfill, Semarang-Indonesia. There are 4 bioreactor landfills operated: 2 anaerobic bioreactors with leachate recirculation and addition of water, and 2 aerobic bioreactors. Different results are shown from these two types of bioreactor, where aerobic bioreactors reach
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Ritonja, Jozef, Andreja Gorsek, and Darja Pecar. "Control of Milk Fermentation in Batch Bioreactor." Elektronika ir Elektrotechnika 26, no. 1 (2020): 4–9. http://dx.doi.org/10.5755/j01.eie.26.1.23377.

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In this paper, modelling and control of a batch bioreactor is studied. A main disadvantage of batch bioreactors compared to other types of bioreactors is their inability to introduce biological or/and chemical substances during operation. Therefore, possibility of bioreactor’s control by means of changing temperature was proposed, analyzed, and implemented. A new supplementary input/output dynamical mathematical model, which considers influence of heating and cooling on a bioprocess, was developed. On a basis of this model, a control system was designed and a method for tuning of the controlle
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Dzianik, František, and Štefan Gužela. "Basic Technological Parameters of the Activation Process for Two Bioreactor Configurations." Strojnícky časopis - Journal of Mechanical Engineering 73, no. 1 (2023): 43–54. http://dx.doi.org/10.2478/scjme-2023-0004.

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Abstract Technological parameters of the activation process in wastewater treatment plant activation systems are analyzed for basic bioreactor configurations, for the chemostat and for the plug flow, both with the recirculation of concentrated activated sludge. The first type of bioreactors represents conventional aerated tanks, but also loop bioreactors. The second type of bioreactors includes, for example, oxidation ditches. The paper presents an evaluation of the basic technological parameters of the activation process for the two mentioned configurations of bioreactor systems with recircul
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Wiharyanto, Oktiawan, Sutrisno Endro, and Hadiwidodo Mochtar. "Performance of Semi-Aerobic Solid Waste Bioreactor in relation to Decomposition Process and Biogas Production." E3S Web of Conferences 73 (2018): 07021. http://dx.doi.org/10.1051/e3sconf/20187307021.

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Solid waste which is sent to Jatibarang landfill in Semarang City can reach up to 4000 m3/day. The composition of solid waste consists of 61.95% of organic waste and 38.05% of inorganic waste. The environmental impacts of solid waste can be reduced using bioreactor methods which being able to accelerate the solid waste decomposition. Large amount of solid waste which is sent to Jatibarang landfill certainly has great potential to environment pollution. Therefore, a technology such as landfill bioreactor is needed to speed up the decomposition process of organic solid waste. Landfill bioreactor
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Christianson, Laura E., Richard A. Cooke, Christopher H. Hay, et al. "Effectiveness of Denitrifying Bioreactors on Water Pollutant Reduction from Agricultural Areas." Transactions of the ASABE 64, no. 2 (2021): 641–58. http://dx.doi.org/10.13031/trans.14011.

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HighlightsDenitrifying woodchip bioreactors treat nitrate-N in a variety of applications and geographies.This review focuses on subsurface drainage bioreactors and bed-style designs (including in-ditch).Monitoring and reporting recommendations are provided to advance bioreactor science and engineering.Abstract. Denitrifying bioreactors enhance the natural process of denitrification in a practical way to treat nitrate-nitrogen (N) in a variety of N-laden water matrices. The design and construction of bioreactors for treatment of subsurface drainage in the U.S. is guided by USDA-NRCS Conservatio
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Lim, B. R., H. Y. Hu, N. Goto, and K. Fujie. "PVA-coated activated carbon for aerobic biological treatment of concentrated refractory organic wastewater." Water Science and Technology 42, no. 3-4 (2000): 205–10. http://dx.doi.org/10.2166/wst.2000.0381.

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The treatment characteristics of concentrated p-phenol sulfonic acid (PSA) wastewater in a submerged bioreactor and a solid phase bioreactor packed with ACP particles (polyvinyl alcohol particles coated with powered activated carbon) were compared experimentally. The changes in biomass and microbial community with the degradation of PSA at both bioreactors were also evaluated using microbial quinones as an index. Greater than 95% of influent PSA was mineralized at the solid phase bioreactor under the volumetric loading of PSA ranging from 0.3 to 1.8 kg-C·m-3·d-1 at the steady state, but less t
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Catapano, Gerardo, Juliane K. Unger, Elisabetta M. Zanetti, Gionata Fragomeni, and Jörg C. Gerlach. "Kinetic Analysis of Lidocaine Elimination by Pig Liver Cells Cultured in 3D Multi-Compartment Hollow Fiber Membrane Network Perfusion Bioreactors." Bioengineering 8, no. 8 (2021): 104. http://dx.doi.org/10.3390/bioengineering8080104.

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Liver cells cultured in 3D bioreactors is an interesting option for temporary extracorporeal liver support in the treatment of acute liver failure and for animal models for preclinical drug screening. Bioreactor capacity to eliminate drugs is generally used for assessing cell metabolic competence in different bioreactors or to scale-up bioreactor design and performance for clinical or preclinical applications. However, drug adsorption and physical transport often disguise the intrinsic drug biotransformation kinetics and cell metabolic state. In this study, we characterized the intrinsic kinet
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Dissertations / Theses on the topic "Bioreactor"

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Shieh, Martin T. "Combined bioreaction and separation in a simulated counter-current chromatographic bioreactor-separator system." Thesis, Aston University, 1994. http://publications.aston.ac.uk/9691/.

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The objective of this work has been to investigate the principle of combined bioreaction and separation in a simulated counter-current chromatographic bioreactor-separator system (SCCR-S). The SCCR-S system consisted of twelve 5.4cm i.d x 75cm long columns packed with calcium charged cross-linked polystyrene resin. Three bioreactions, namely the saccharification of modified starch to maltose and dextrin using the enzyme maltogenase, the hydrolysis of lactose to galactose and glucose in the presence of the enzyme lactase and the biosynthesis of dextran from sucrose using the enzyme dextransucra
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Ntwampe, Seteno Karabo Obed. "Multicapillary membrane bioreactor design." Thesis, Cape Peninsula University of Technology, 2005. http://hdl.handle.net/20.500.11838/897.

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Thesis (MTech (Chemical Engineering))--Cape Peninsula University of Technology, 2005<br>The white rot fungus, Phanerochaete chrysosporium, produces enzymes, which are capable of degrading chemical pollutants. It was detennined that this fungus has multiple growth phases. The study provided infonnation that can be used to classify growth kinetic parameters, substrate mass transfer and liquid medium momentum transfer effects in continuous secondary metabolite production studies. P. chrysosporium strain BKMF 1767 (ATCC 24725) was grown at 37 QC in single fibre capillary membrane bioreac
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Du, Preez Ryne. "Development of a membrane immobilised amidase bioreactor system." Thesis, Link to the online version, 2008. http://hdl.handle.net/10019/1996.

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Grudzien, Lukasz Andrzej. "Enantioseparation using a counter-current bioreactor." Thesis, Brunel University, 2011. http://bura.brunel.ac.uk/handle/2438/6496.

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The potential of countercurrent chromatography (CCC) as a small footprint bioreactor/separator for manufacture of enantiopure chiral molecules was explored, using as a model reaction the isolation of L-amino butyric acid (L-ABA) from a DL-ABA racemate and the enantioselectivity of D-amino acid oxidase (DAAO). Bioconversion of D-ABA to ketobutyric acid (KBA) by DAAO, immobilised by selective partitioning in the stationary phase of the CCC centrifuge, was accompanied by separation of unreacted L-ABA from KBA by the countercurrent action of the centrifuge. For effective bioreactor/separator actio
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Radocaj, Olgica. "Ethanol fermentation in a membrane bioreactor." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0015/MQ45840.pdf.

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Ramlogan, Anil Shiva. "Stem cell expansion and bioreactor development." Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/676.

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A major challenge to the clinical success of cell-based tissue engineering strategies is the ability to obtain sufficient numbers of cells within an acceptable time frame. The expansion of cells on microcarriers within spinner flask bioreactor has shown promise in meeting that challenge. Spinner flask microcarrier technology is space-saving and media utilisation efficient. However, further optimisation in terms of, for example, seeding efficiency, expansion rates and harvest efficiency is necessary to realise the clinical potential of this technology. The present work is designed to improve ce
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Griswold, Aaron A. (Aaron Alexander) 1981. "pH control in a miniaturized bioreactor." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/32812.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2004.<br>Includes bibliographical references (leaf 18).<br>A miniaturized bioreactor with a volume on the order of 100 [micro]l has been built with the aim of increasing the efficiency of the screening process for various microbial cultures. Unlike larger reactors currently in use, the current miniaturized design lacks a method of pH control. Without pH control, cell growth can be hindered or even stopped altogether when the growing medium becomes too acidic. Using technology already in place to optically me
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Carrier, Rebecca Lyn 1973. "Cardiac tissue engineering : bioreactor cultivation parameters." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/8999.

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Thesis (Sc.D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2000.<br>Includes bibliographical references.<br>Tissue engineering may be useful in fighting heart disease since it offers the possibility of creating functional tissue equivalents for scientific studies and tissue repair. In the present work, we examined how variations in cultivation parameters of a model tissue engineering system influenced cardiac tissue morphogenesis. The central hypothesis was that using a tissue engineering system consisting of isolated cardiac cells, polymer scaffolds, and tissue cult
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Germain, E. A. M. "Biomass effects on membrane bioreactor operations." Thesis, Cranfield University, 2004. http://dspace.lib.cranfield.ac.uk/handle/1826/11032.

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Diverse operating parameters were investigated for their effects on biomass characteristics, membrane fouling and aeration efficiency in submerged membrane bioreactors (MBRS). The characteristics of the solid phase of the biomass were affected by the biomass state (unstabilised, stabilising and stabilised) and by the SRT and HRT, whereas the characteristics of the liquid phase appeared to be more dependent on inuent composition and strength. Under operating conditions at constant SRT and HRT, the biomass characteristics reached their stabilised state aer 1.0±0.3 SRT. The impact of membrane aer
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BERNOCCO, MARCO. "Bioreactor engineering for tissue engineering application." Doctoral thesis, Politecnico di Torino, 2013. http://hdl.handle.net/11583/2513796.

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Lo scopo di questo lavoro di tesi è la caratterizzazione metrologica di un bioreattore con l’intento di aumentare la riproducibilità e l’affidabilità dei processi di Ingegneria tessutale (Tissue Engineering, TE). La Tissue engineering (TE) o ingegneria dei tessuti è la disciplina che studia la comprensione dei principi della crescita dei tessuti, e la loro applicazione per produrre tessuto funzionale per uso clinico o diagnostico. Uno dei principali scopi della TE è l’impiego di tessuti in crescita naturale extracorporea per la medicina rigenerativa, in altre parole lo sviluppo di strategie te
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Books on the topic "Bioreactor"

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Reinhart, Debra R. Landfill bioreactor design and operation. Lewis Publishers, 1998.

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Mota, Manuel, and Johannes Tramper. Multiphase Bioreactor Design. Edited by Joaquim M. S. Cabral. Taylor & Francis, 2001. http://dx.doi.org/10.4324/9780203303047.

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1949-, Tramper J., ed. Basic bioreactor design. M. Dekker, 1991.

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S, Cabral Joaquim, Mota Manuel, and Tramper J. 1949-, eds. Multiphase bioreactor design. Taylor & Francis, 2001.

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1949-, Tramper J., ed. Basic bioreactor design. M. Dekker, 1991.

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1949-, Asenjo Juan A., and Merchuk José C. 1938-, eds. Bioreactor system design. M. Dekker, 1995.

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Sarkar, Sushovan. Fixed Bed Hybrid Bioreactor. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-4546-1.

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Cort, Wrotnowski, and Business Communications Co, eds. The changing bioreactor business. Business Communications Co., 1990.

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F, Bliem R., ed. Bioreactor systems and effects. Springer-Verlag, 1991.

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Kasper, Cornelia, Martijn van Griensven, and Ralf Pörtner, eds. Bioreactor Systems for Tissue Engineering. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-69357-4.

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Book chapters on the topic "Bioreactor"

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Geada, Pedro, António A. Vicente, and José A. Teixeira. "Bioreactor." In Bioreactor Technology in Food Processing. CRC Press, 2024. http://dx.doi.org/10.1201/9780429424236-3.

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Mudde, Rob, Henk Noorman, and Matthias Reuss. "Bioreactor Modeling." In Industrial Biotechnology. Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527807833.ch3.

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Schügerl, Karl, and Karl-Heinz Bellgardt. "Bioreactor Models." In Bioreaction Engineering. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59735-0_2.

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Nielsen, Jens, and John Villadsen. "Bioreactor Modeling." In Bioreaction Engineering Principles. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4757-4645-7_9.

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Hopkins, David, Melissa St. Amand, and Jack Prior. "Bioreactor Automation." In Manual of Industrial Microbiology and Biotechnology. ASM Press, 2014. http://dx.doi.org/10.1128/9781555816827.ch51.

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Wang, Zhiwei. "Bioreactor Membrane." In Encyclopedia of Membranes. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-40872-4_2158-1.

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Kossen, N. W. F. "Bioreactor Engineering." In Advances in Bioprocess Engineering. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-017-0641-4_1.

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Hettiaratchi, J. Patrick A. "Landfill landfill/landfilling Bioreactors landfill/landfilling bioreactor." In Encyclopedia of Sustainability Science and Technology. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0851-3_114.

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Zeilinger, Katrin, and Jörg C. Gerlach. "Artificial Liver Bioreactor Design." In Bioreactors. Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527683369.ch5.

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Abu Hassan, Affrida, Norazlina Noordin, Zaiton Ahmad, Mustapha Akil, Faiz Ahmad, and Rusli Ibrahim. "Protocol for Mass Propagation of Plants Using a Low-Cost Bioreactor." In Efficient Screening Techniques to Identify Mutants with TR4 Resistance in Banana. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-64915-2_11.

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AbstractConventional in vitro mass propagation methods are labour-intensive, costly and have a low degree of automation. Bioreactor or automated growth vessel systems using liquid media were developed to overcome these problems. The use of liquid instead of solid culture medium for plant micropropagation offers better access to medium components and scalability through automation. However, the cost of setting up a bioreactor system is one of its disadvantages as such systems are expensive with limited number of manufacturers. A low-cost bioreactor system was set up using recycled, low biodegra
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Conference papers on the topic "Bioreactor"

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Cho, Bovinille Anye, George Mbella Teke, Godfrey K. Gakingo, Robert W. M. Pott, and Dongda Zhang. "CFD Simulations of Mixing Dynamics and Photobioreaction Kinetics in Miniature Bioreactors under Transitional Flow Regimes." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.197756.

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Miniaturised stirred bioreactors are crucial in high-throughput bioprocesses for their simplicity and cost-effectiveness. To accelerate process optimisation in chemical and bioprocess industries, models that integrate CFD-predicted flow fields with (bio)reaction kinetics are needed. However, conventional two-step coupling methods, which freeze flow fields after solving hydrodynamics and then address (bio)reaction transport, face numerical challenges in miniaturised systems due to unsteady radial flows, recirculation zones, and secondary vortices. These flow fluctuations prevent steady-state hy
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Tsao, Yow-Min D., Steve R. Gonda, and Neal R. Pellis. "Mass Transfer Characteristics of NASA Bioreactors by Numerical Simulation." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-1313.

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Abstract In this study, two bioreactors, each consisting of two concentric independently rotating cylinders, were evaluated by using computational fluid dynamics. The relative motion between the culture fluid (125 ml in the low aspect bioreactor and 250 ml in the high aspect bioreactor) and particles (150–3,000 micron diameter) was generated by a secondary flow resulting from different rotation rates of the two concentric cylinders. This study included computation of flow fields, perfusion effects, particle trajectories, shear forces and Sherwood number. Results indicate that the larger partic
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Pereira, Pedro M., Bruno S. Ferreira, and Fernando P. Bernardo. "Multi-Dimensional Singular Value Decomposition of Scale-Varying CFD Data: Analyzing Scale-Up Effects in Fermentation Processes." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.129601.

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The scale-up of processes with complex fluid flow presents significant challenges in process engineering, particularly in fermentation. Computational fluid dynamics (CFD) is a crucial tool for accurately modelling the hydrodynamic environment in bioreactors and understanding the effects of scale-up. This study utilizes Higher Order SVD (HOSVD), which is the multidimensional extension of Singular Value Decomposition (SVD), to identify the dominant structures (modes) of fluid flow in CFD data of fermentation process simulations. Similarly to Proper Orthogonal Decomposition (POD), also based on S
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Yin, Bei, and Jennifer Collin. "A Study of Biofilm Growth and Control in Porous Media Bioreactors." In CORROSION 2014. NACE International, 2014. https://doi.org/10.5006/c2014-4129.

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Abstract Uncontrolled microbial growth in oil and gas reservoirs may lead to microbiologically influenced formation damage (MIFD), including but not limited to (i) reservoir souring due to H2S production, which can also cause health issues and downstream pipeline and equipment corrosion, and (ii) reservoir permeability decrease due to clogging with biofilm. In this paper, we present results from studies which illustrate the negative impact of biofouling in laboratory-scale porous media bioreactors and the impact of biocide treatments on the prevention and mitigation of the effects of MIFD. Por
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Reid, Craig, and Dave Christie. "Corrosion in Secondary Effluent Treatment Systems." In CORROSION 2004. NACE International, 2004. https://doi.org/10.5006/c2004-04250.

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Abstract Microbiologically influenced corrosion (MIC) has occurred in activated sludge effluent treatment systems in several Canadian mills. Carbon steel recycled activated sludge (RAS) piping and type 316L stainless steel clear effluent piping have perforated in less than 10 years of service due to corrosion by sulfate reducing bacteria (SRB). In the vapour space of bioreactors sulphuric acid produced by sulfur oxidizing bacteria (SOX) has caused severe corrosion of concrete and type 304 stainless steel agitator shafts in one mill. In the case of SRB corrosion of carbon steel RAS piping and 3
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Mexis, Konstantinos, Stefanos Xenios, Nikolaos Trokanas, and Antonis Kokossis. "A Physics-Informed Approach to Dynamic Modeling and Parameter Estimation in Biotechnology." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.122347.

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The increasing complexity of industrial biotechnology demands advanced modeling techniques capable of capturing the intricate dynamics of bioreactors. Traditional regression-based and empirical methods often fall short when confronted with the highly nonlinear behavior and limited experimental data characteristic of bioprocesses. Addressing these challenges requires a more intelligent approach�one that leverages domain knowledge to model complex bioprocess dynamics effectively, even with sparse data, while maintaining interpretability and robustness. In this study, we introduce a process-infor
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Cruel, Magali, Morad Bensidhoum, Laure Sudre, Guillaume Puel, Virginie Dumas, and Thierry Hoc. "Study of the Effect of Mechanical Loading on Cell Cultures in Bone Tissue Engineering." In ASME 2012 11th Biennial Conference on Engineering Systems Design and Analysis. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/esda2012-82989.

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Bone tissue engineering currently represents one of the most interesting alternatives to autologous transplants and their drawbacks in the treatment of large bone defects. Mesenchymal stem cells are used to build new bone in vitro in a bioreactor. Their stimulation and our understanding of the mechanisms of mechanotransduction need to be improved in order to optimize the design of bioreactors. In this study, several geometries of bioreactor were analyzed experimentally and biological results were linked with numerical simulations of the flow inside the bioreactor. These results will constitute
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Kadic, Enes, and Theodore J. Heindel. "Hydrodynamic Considerations in Bioreactor Selection and Design." In ASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting collocated with 8th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-30367.

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The biological production of renewable fuels and chemicals, medicines, and proteins is not possible without a properly functioning bioreactor. Bioreactors are expected to meet several basic requirements and create conditions favorable to the biological material such that the desired production is maximized. The basic requirements, which are strongly influenced by fluid mechanic principles, may include minimum damage to the biological material, maximum reactor volume utilization, optimized gas-liquid mass transfer, and/or enhanced mass transfer from the liquid to the biological species. Each of
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Neitzel, G. Paul, Robert M. Nerem, Athanassios Sambanis, et al. "Effect of Fluid-Mechanical and Chemical Environments on Cell Function and Tissue Growth: Experimental and Modeling Studies." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-0794.

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Abstract Bioreactors are widely used for the growth and maintenance of tissue-engineered constructs. In this paper, we report on work directed toward a better understanding of the chemical and fluid-mechanical environments that are needed to enhance cell function and tissue growth in bioreactors. We have conducted cell-growth studies in well-controlled flow conditions that indicate the effect of shear stress and oxygen tension on cellular function. In more complicated bioreactors, like the NASA rotating-wall vessel bioreactor, we have done experimental and numerical fluid-mechanical studies th
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Bertrand, Robert S., Emmanuel Revellame, Lisa Stephanie Dizon, Kristel Gatdula, and Remil Aguda. "Measurement of Volumetric Mass Transfer Coefficient in Lab-scale Stirred Tank Reactors: Is There a Point of Diminishing Returns for Impeller Speed and Gas Flowrate?" In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/zrrh2541.

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Abstract:
The transfer of species from gas to liquid across the phase interface is generally regarded as the greatest challenge and limitation in bioreactor design and operation. This is true for both oxygen and other gases used in bioreactors, such as methane. In this study, the volumetric oxygen transfer coefficient was observed for a bioreactor at various sparger flowrates and impeller rotational speeds. Specifically targeted was a point at which increasing the impeller speed or gas flowrate resulted in reduced returns on the observed value of the transfer coefficient. This was to be expected, but mu
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Reports on the topic "Bioreactor"

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Turick, C. E., and M. E. Mcllwain. Review of nonconventional bioreactor technology. Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10193551.

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2

Christianson, Laura E., Matthew J. Helmers, and Carl H. Pederson. Denitrification Bioreactor in Northeast Iowa. Iowa State University, Digital Repository, 2011. http://dx.doi.org/10.31274/farmprogressreports-180814-1167.

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Helmers, Matt, and Carl Pederson. Denitrification Bioreactor in Northeast Iowa. Iowa State University, Digital Repository, 2017. http://dx.doi.org/10.31274/farmprogressreports-180814-1634.

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4

Christianson, Laura E., Matthew J. Helmers, and Carl H. Pederson. Hydraulic Performance of the Denitrification Bioreactor. Iowa State University, Digital Repository, 2012. http://dx.doi.org/10.31274/farmprogressreports-180814-588.

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5

Okeke, Benedict. Farm Deployable Microbial Bioreactor for Fuel Ethanol Production. Office of Scientific and Technical Information (OSTI), 2016. http://dx.doi.org/10.2172/1244609.

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Oldenburg, Curtis M. T2LBM Version 1.0: Landfill bioreactor model for TOUGH2. Office of Scientific and Technical Information (OSTI), 2001. http://dx.doi.org/10.2172/799552.

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Barton & Loguidice, P. C. Mill Seat Landfill Bioreactor Renewable Green Power (NY). Office of Scientific and Technical Information (OSTI), 2010. http://dx.doi.org/10.2172/1051540.

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Basu, R., K. T. Klasson, E. C. Clausen, and J. L. Gaddy. Biological conversion of synthesis gas. Topical report: Bioreactor studies. Office of Scientific and Technical Information (OSTI), 1993. http://dx.doi.org/10.2172/10122053.

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Berry, C. J. Test Plan for Methanotrophic Bioreactor at Savannah River Site-TNX. Office of Scientific and Technical Information (OSTI), 1994. http://dx.doi.org/10.2172/69362.

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Ramin Yazdani, Jeff Kieffer, Kathy Sananikone, and Don Augenstein. Full Scale Bioreactor Landfill for Carbon Sequestration and Greenhouse Emission Control. Office of Scientific and Technical Information (OSTI), 2005. http://dx.doi.org/10.2172/912519.

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