Academic literature on the topic 'Bioresponsive'
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Journal articles on the topic "Bioresponsive"
Ulijn, Rein V., Nurguse Bibi, Vineetha Jayawarna, Paul D. Thornton, Simon J. Todd, Robert J. Mart, Andrew M. Smith, and Julie E. Gough. "Bioresponsive hydrogels." Materials Today 10, no. 4 (April 2007): 40–48. http://dx.doi.org/10.1016/s1369-7021(07)70049-4.
Full textWilson, A. Nolan, and Anthony Guiseppi-Elie. "Bioresponsive Hydrogels." Advanced Healthcare Materials 2, no. 4 (December 10, 2012): 520–32. http://dx.doi.org/10.1002/adhm.201200332.
Full textKim, Jongseong, Satish Nayak, and L. Andrew Lyon. "Bioresponsive Hydrogel Microlenses." Journal of the American Chemical Society 127, no. 26 (July 2005): 9588–92. http://dx.doi.org/10.1021/ja0519076.
Full textYu, Jicheng, Yuqi Zhang, Anna R. Kahkoska, and Zhen Gu. "Bioresponsive transcutaneous patches." Current Opinion in Biotechnology 48 (December 2017): 28–32. http://dx.doi.org/10.1016/j.copbio.2017.03.001.
Full textTrotta, Francesco, Fabrizio Caldera, Chiara Dianzani, Monica Argenziano, Giuseppina Barrera, and Roberta Cavalli. "Glutathione Bioresponsive Cyclodextrin Nanosponges." ChemPlusChem 81, no. 5 (December 15, 2015): 439–43. http://dx.doi.org/10.1002/cplu.201500531.
Full textTrotta, Francesco, Fabrizio Caldera, Chiara Dianzani, Monica Argenziano, Giuseppina Barrera, and Roberta Cavalli. "Glutathione Bioresponsive Cyclodextrin Nanosponges." ChemPlusChem 81, no. 5 (March 15, 2016): 434. http://dx.doi.org/10.1002/cplu.201600105.
Full textWang, Meng, Benqing Zhou, Lu Wang, Feifan Zhou, Nataliya Smith, Debra Saunders, Rheal A. Towner, Jun Song, Junle Qu, and Wei R. Chen. "Biodegradable pH-responsive amorphous calcium carbonate nanoparticles as immunoadjuvants for multimodal imaging and enhanced photoimmunotherapy." Journal of Materials Chemistry B 8, no. 36 (2020): 8261–70. http://dx.doi.org/10.1039/d0tb01453b.
Full textXin, Xiaoqian, Zhongxia Zhang, Xican Zhang, Jian Chen, Xi Lin, Pinghua Sun, and Xiaowen Liu. "Bioresponsive nanomedicines based on dynamic covalent bonds." Nanoscale 13, no. 27 (2021): 11712–33. http://dx.doi.org/10.1039/d1nr02836g.
Full textYou, Jin-Oh, Dariela Almeda, George JC Ye, and Debra T. Auguste. "Bioresponsive matrices in drug delivery." Journal of Biological Engineering 4, no. 1 (2010): 15. http://dx.doi.org/10.1186/1754-1611-4-15.
Full textHeffern, Marie C., Lauren M. Matosziuk, and Thomas J. Meade. "Lanthanide Probes for Bioresponsive Imaging." Chemical Reviews 114, no. 8 (December 13, 2013): 4496–539. http://dx.doi.org/10.1021/cr400477t.
Full textDissertations / Theses on the topic "Bioresponsive"
Deacon, Samuel Philip Edward. "Bioresponsive polymer therapeutics containing coiled-coil motifs." Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/55819/.
Full textWilson, Andrew Nolan. "Drug delivery with feedback control in bioresponsive hydrogels." Thesis, Clemson University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3624014.
Full textBioresponsive hydrogels are emerging with technological significance in targeted drug delivery, biosensors and regenerative medicine. The design challenge is to effectively link the conferred biospecificity with an engineered response tailored to the needs of a particular application. Moreover, the fundamental phenomena governing the response must support an appropriate dynamic range, limit of detection and the potential for feedback control. The design of these systems is inherently complicated due to the high interdependency of the governing phenomena that guide sensing, transduction and actuation of the hydrogel. The objective of the dissertation is to review the current state of bioresponsive hydrogel technology and introduce a method of extending the technology through integrated control loops; explore fundamental phenomena which affect ion transport within biomimetic hydrogels; and investigate, via in silico studies, the fundamental design parameters for the implementation of a feedback control loop within a bioresponsive hydrogel.
In one study, effects of valence number, temperature and polymer swelling on release profiles of monovalent potassium and divalent calcium ions elucidates mechanistic characteristics of polymer interactions with charged species. For comparison, ions were loaded during hydrogel formulation or loaded by partitioning following construct synthesis. Using the Korsmeyer-Peppas release model, the diffusional exponents were found to be Fickian for pre- and post-loaded potassium ions while preloaded calcium ions followed an anomalous behavior and postloaded calcium ions followed Case II behavior. Results indicate divalent cations interact through cation-polyelectrolyte anion complexation while monovalent ions do not interact with the polymer. Temperature dependence of potassium ion release was shown to follow an Arrhenius relation and calcium ion release was temperature independent.
In another study, data generated from the previous Chymotrypsin system is used to build and validate a finite element model. The model provides insight into key engineering parameters for the design of an enzymatically actuated, feedback controlled release. A drug delivery platform comprising a biocompatible, bioresponsive hydrogel and possessing a covalently tethered peptide-inhibitor conjugate was engineered to achieve stasis, via a closed control loop, of the external biochemical activity of the actuating enzyme. The FEM model was used to investigate the release of a competitive protease inhibitor, MAG283, via cleavage of Acetyl-Pro-Leu-Gly|Leu-MAG-283 by MMP-9 in order to achieve targeted homeostasis of MMP-9 activity, a goal for the treatment of chronic wound pathophysiology. It was found the key engineering parameters for the delivery device are the radii of the hydrogel microspheres and the concentration of the peptide-inhibitor conjugate loaded into the hydrogel.
Homeostatic drug delivery, where the focus turns away from the drug release rate and turns towards achieving targeted control of biochemical activity within a biochemical pathway, is an emerging approach in drug delivery methodologies for which the potential has not yet been fully realized. By understanding mechanistic phenomena and key engineering parameters for design, advancements in bioresponsive hydrogels will continue to produce novel technologies in biomedical applications.
Bolarinwa, Aminat. "The formulation of a bioresponsive ceramic bone replacement." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/1073/.
Full textPhilipp, Alexander. "Delivery of siRNA with bioresponsive cationic polymer-based carriers." Diss., lmu, 2010. http://d-nb.info/1000906132/34.
Full textHopkinson, Devan. "Bioresponsive liposomes to target drug release in alveolar macrophages." Thesis, University of Manchester, 2017. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713597.
Full textAshrafi, Koorosh. "Novel bioresponsive drug eluting microspheres to enhance chemoembolisation therapy." Thesis, University of Brighton, 2014. https://research.brighton.ac.uk/en/studentTheses/d72e0cce-8b99-4659-9b8d-c0e5a48da701.
Full textGilbert, Helena Rosalind Petra. "Bioresponsive polymer-protection conjugates as a unimolecular drug delivery system." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55685/.
Full textFerguson, Elaine Lesley. "Bioresponsive polymer-phospholipase A2 conjugates as novel anti-cancer agents." Thesis, Cardiff University, 2008. http://orca.cf.ac.uk/55750/.
Full textMehta, Ankit N. "Tampon-like Foam Structures for Bioresponsive Vaginal Drug Delivery Applications." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1396522494.
Full textBonner, Daniel Kenneth. "Understanding barriers to efficient nucleic acid delivery with bioresponsive block copolymers." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/70811.
Full textCataloged from PDF version of thesis.
Includes bibliographical references.
The delivery of nucleic acids has the potential to revolutionize medicine by allowing previously untreatable diseases to be clinically addressed. Viral delivery systems have been held back by immunogenicity and toxicity concerns, but synthetic vectors have lagged in transfection efficiency. This thesis describes the rational design and systematic study of three classes of bioresponsive polymers for nucleic acid delivery. A central theme of the study was understanding how the structure of the polymers impacted each of the intracellular steps of delivery, rather than solely the end result. A powerful tool for efficiently quantifying endosomal escape was developed and applied to each of the material systems described. First, a linear-dendritic poly(amido amine) -poly(ethylene glycol) (PAMAM-PEG) block copolymer system previously developed in our lab was evaluated and its ability to overcome the sequential barriers of uptake, endosomal escape, and nuclear import were characterized. Next, a class of crosslinked linear polyethyleimine (xLPEI) hyperbranched polymers, which can contain disulfideresponsive linkages, were synthesized and investigated. It was demonstrated that free polymer in solution, not the presence of a functional bioresponsive domain, was responsible for the highly efficient and relatively nontoxic DNA delivery of this promising class of crosslinked polyamines. Finally, this analysis was applied to siRNA delivery by a library of amine-functionalized synthetic polypeptides. The pH-responsive secondary structure, micelle formation, and ester hydrolysis were studied prior to the discrete barrier-oriented analysis of the siRNA delivery potential of this library. It is hoped that the tools, materials, and systemic analysis of structure-function relationships in this thesis will enhance the process of discovery and development of clinically relevant gene carriers.
by Daniel Kenneth Bonner.
Ph.D.
Books on the topic "Bioresponsive"
Santin, Matteo, and Gary Phillips, eds. Biomimetic, Bioresponsive, and Bioactive Materials. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118129906.
Full textBiomimetic, bioresponsive, and bioactive materials: An introduction to integrating materials with tissues. Hoboken, NJ: Wiley, 2012.
Find full textHock, Bertold, ed. Bioresponse-Linked Instrumental Analysis. Wiesbaden: Vieweg+Teubner Verlag, 2001. http://dx.doi.org/10.1007/978-3-322-86568-7.
Full textPatel, Deepa H. Bioresponsive Polymers: Design and Application in Drug Delivery. Apple Academic Press, Incorporated, 2020.
Find full textPatel, Deepa H. Bioresponsive Polymers: Design and Application in Drug Delivery. Apple Academic Press, Incorporated, 2020.
Find full textPatel, Deepa H. Bioresponsive Polymers: Design and Application in Drug Delivery. Apple Academic Press, Incorporated, 2020.
Find full textPatel, Deepa H. Bioresponsive Polymers: Design and Application in Drug Delivery. Apple Academic Press, Incorporated, 2020.
Find full textSantin, Matteo, and Gary J. Phillips. Biomimetic, Bioresponsive, and Bioactive Materials: An Introduction to Integrating Materials with Tissues. Wiley & Sons, Incorporated, John, 2012.
Find full textSantin, Matteo, and Gary J. Phillips. Biomimetic, Bioresponsive, and Bioactive Materials: An Introduction to Integrating Materials with Tissues. Wiley & Sons, Incorporated, John, 2012.
Find full textBook chapters on the topic "Bioresponsive"
Pathak, Drashti, and Deepa H. Patel. "Bioresponsive Nanoparticles." In Bioresponsive Polymers, 173–95. Includes bibliographical references and index.: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429325243-6.
Full textPatel, Deepa H., Drashti Pathak, and Neelang Trivedi. "Introduction to Bioresponsive Polymers." In Bioresponsive Polymers, 1–40. Includes bibliographical references and index.: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429325243-1.
Full textPatel, Anita, Jayvadan K. Patel, and Deepa H. Patel. "Design of Bioresponsive Polymers." In Bioresponsive Polymers, 41–71. Includes bibliographical references and index.: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429325243-2.
Full textLalan, Manisha, Deepti Jani, Pratiksha Trivedi, and Deepa H. Patel. "Application of Bioresponsive Polymers in Drug Delivery." In Bioresponsive Polymers, 73–119. Includes bibliographical references and index.: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429325243-3.
Full textWilliam, Tamgue Serges, Drashti Pathak, and Deepa H. Patel. "Application of Bioresponsive Polymers in Gene Delivery." In Bioresponsive Polymers, 121–50. Includes bibliographical references and index.: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429325243-4.
Full textPathak, Drashti, and Deepa H. Patel. "Recent Developments in Bioresponsive Drug Delivery Systems." In Bioresponsive Polymers, 151–72. Includes bibliographical references and index.: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429325243-5.
Full textWilliam, Tamgue Serges, Dipali Talele, and Deepa H. Patel. "Bioresponsive Hydrogels for Controlled Drug Delivery." In Bioresponsive Polymers, 197–232. Includes bibliographical references and index.: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429325243-7.
Full textLi, Xue, and Michael J. Serpe. "Bioresponsive Hydrogels and Microgels." In Chemistry of Bioconjugates, 370–86. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9781118775882.ch15.
Full textSavii, Cecilia, and Ana-Maria Putz. "Recent Advances in Bioresponsive Nanomaterials." In Carbon Bonding and Structures, 379–435. Dordrecht: Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-1733-6_16.
Full textSantin, Matteo, and Gary Phillips. "History of Biomimetic, Bioactive and Bioresponsive Biomaterials." In Biomimetic, Bioresponsive, and Bioactive Materials, 1–34. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118129906.ch1.
Full textConference papers on the topic "Bioresponsive"
"BIORESPONSE TO STEREOSCOPIC MOVIES PRESENTED VIA A HEAD-MOUNTED DISPLAY." In International Conference on Bio-inspired Systems and Signal Processing. SciTePress - Science and and Technology Publications, 2011. http://dx.doi.org/10.5220/0003155104330437.
Full textReports on the topic "Bioresponsive"
Hamilton, Mark F., Sarah L. Gourlie, and Paul A. Waters. Human Bioresponse to Low-Frequency Underwater Sound. Fort Belvoir, VA: Defense Technical Information Center, February 2009. http://dx.doi.org/10.21236/ada494255.
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