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Journal articles on the topic 'Biosensor applications'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 February 2022

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1

Carpenter, Alexander, Ian Paulsen, and Thomas Williams. "Blueprints for Biosensors: Design, Limitations, and Applications." Genes 9, no. 8 (2018): 375. http://dx.doi.org/10.3390/genes9080375.

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Biosensors are enabling major advances in the field of analytics that are both facilitating and being facilitated by advances in synthetic biology. The ability of biosensors to rapidly and specifically detect a wide range of molecules makes them highly relevant to a range of industrial, medical, ecological, and scientific applications. Approaches to biosensor design are as diverse as their applications, with major biosensor classes including nucleic acids, proteins, and transcription factors. Each of these biosensor types has advantages and limitations based on the intended application, and th

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2

Gilani Mohamed, Mohamed Ahmed, Ashok Vajravelu, and Nurmiza Binti Othman. "Biosensors Preliminary Concepts and Its Principles with Applications in the Engineering Perspective." International Journal of Science and Healthcare Research 6, no. 2 (2021): 77–81. http://dx.doi.org/10.52403/ijshr.20210415.

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Biosensor is rapid detection of any infectious disease at the early stages is critical for supporting public health and ensuring effective healthcare outcomes. A timely and accurate diagnosis of a disease is necessary for an effective medical response where is biosensor takes place. The design and development of biosensors have taken a centre stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications, such as health care and disease diagnosis, environmental monitoring, water and food quality monitoring, and drug delivery and lately it shown great

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Karunakaran, Chandran, Murugesan Karthikeyan, Marimuthu Dhinesh Kumar, Ganesan Kaniraja, and Kalpana Bhargava. "Electrochemical Biosensors for Point of care Applications." Defence Science Journal 70, no. 5 (2020): 549–56. http://dx.doi.org/10.14429/dsj.70.16359.

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Biosensor refers to powerful and innovative analytical tool involving biological sensing element and transducer with broad range of applications, such as diagnosis, drug discovery, biomedicine, food safety and processing, environmental monitoring, security and defense. Recent advances in the field of biotechnology, microelectronics, and nanotechnology have improved the development of biosensors. Glucometers utilizing the electrochemical determination of oxygen or hydrogen peroxide employing immobilised glucose oxidase electrode seeded the discovery and development of biosensors. Molecular reco

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Park, Min. "Surface Display Technology for Biosensor Applications: A Review." Sensors 20, no. 10 (2020): 2775. http://dx.doi.org/10.3390/s20102775.

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Surface display is a recombinant technology that expresses target proteins on cell membranes and can be applied to almost all types of biological entities from viruses to mammalian cells. This technique has been used for various biotechnical and biomedical applications such as drug screening, biocatalysts, library screening, quantitative assays, and biosensors. In this review, the use of surface display technology in biosensor applications is discussed. In detail, phage display, bacterial surface display of Gram-negative and Gram-positive bacteria, and eukaryotic yeast cell surface display sys

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Prakash, Shaurya, Marie Pinti, and Bharat Bhushan. "Theory, fabrication and applications of microfluidic and nanofluidic biosensors." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 370, no. 1967 (2012): 2269–303. http://dx.doi.org/10.1098/rsta.2011.0498.

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Biosensors are a broad array of devices that detect the type and amount of a biological species or biomolecule. Several different types of biosensors have been developed that rely on changes to mechanical, chemical or electrical properties of the transduction or sensing element to induce a measurable signal. Often, a biosensor will integrate several functions or unit operations such as sample extraction, manipulation and detection on a single platform. This review begins with an overview of the current state-of-the-art biosensor field. Next, the review delves into a special class of biosensors

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Jiang, Pengfei, Yulin Wang, Lan Zhao, Chenyang Ji, Dongchu Chen, and Libo Nie. "Applications of Gold Nanoparticles in Non-Optical Biosensors." Nanomaterials 8, no. 12 (2018): 977. http://dx.doi.org/10.3390/nano8120977.

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Due to their unique properties, such as good biocompatibility, excellent conductivity, effective catalysis, high density, and high surface-to-volume ratio, gold nanoparticles (AuNPs) are widely used in the field of bioassay. Mainly, AuNPs used in optical biosensors have been described in some reviews. In this review, we highlight recent advances in AuNP-based non-optical bioassays, including piezoelectric biosensor, electrochemical biosensor, and inductively coupled plasma mass spectrometry (ICP-MS) bio-detection. Some representative examples are presented to illustrate the effect of AuNPs in

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Wu, Jiyun, and Qiuyao Wu. "The Review of Biosensor and its Application in the Diagnosis of COVID-19." E3S Web of Conferences 290 (2021): 03028. http://dx.doi.org/10.1051/e3sconf/202129003028.

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The objective of this article is to summarize the available technologies for biosensing applications in COVID-19. The article is divided into three parts, an introduction to biosensing technologies, applications of mainstream biosensing technologies and a review of biosensing applications in COVID-19. The introduction of biosensors presents the history of inventing the biosensing technology, which refers to the ISFET. The resonant biosensor with the example of MEMS. the principle of optical biosensor, and the thermal biosensor. In the second part, the main use of biosensing techniques, it was

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Wang, Xingya, and Guangchang Pang. "Amplification systems of weak interaction biosensors: applications and prospects." Sensor Review 35, no. 1 (2015): 30–42. http://dx.doi.org/10.1108/sr-03-2014-629.

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Purpose – This paper aims to provide a detailed review of weak interaction biosensors and several common biosensor methods for magnifying signals, as well as judiciously guide readers through selecting an appropriate detecting system and signal amplification method according to their research and application purpose. Design/methodology/approach – This paper classifies the weak interactions between biomolecules, summarizes the common signal amplification methods used in biosensor design and compares the performance of different kinds of biosensors. It highlights a potential electrochemical sign

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Schackart, Kenneth E., and Jeong-Yeol Yoon. "Machine Learning Enhances the Performance of Bioreceptor-Free Biosensors." Sensors 21, no. 16 (2021): 5519. http://dx.doi.org/10.3390/s21165519.

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Since their inception, biosensors have frequently employed simple regression models to calculate analyte composition based on the biosensor’s signal magnitude. Traditionally, bioreceptors provide excellent sensitivity and specificity to the biosensor. Increasingly, however, bioreceptor-free biosensors have been developed for a wide range of applications. Without a bioreceptor, maintaining strong specificity and a low limit of detection have become the major challenge. Machine learning (ML) has been introduced to improve the performance of these biosensors, effectively replacing the bioreceptor

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Nielsen, Michael, Lars Hauer Larsen, Mike S. M. Jetten, and Niels Peter Revsbech. "Bacterium-Based NO2− Biosensor for Environmental Applications." Applied and Environmental Microbiology 70, no. 11 (2004): 6551–58. http://dx.doi.org/10.1128/aem.70.11.6551-6558.2004.

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ABSTRACT A sensitive NO2 − biosensor that is based on bacterial reduction of NO2 − to N2O and subsequent detection of the N2O by a built-in electrochemical N2O sensor was developed. Four different denitrifying organisms lacking NO3 − reductase activity were assessed for use in the biosensor. The relevant physiological aspects examined included denitrifying characteristics, growth rate, NO2 − tolerance, and temperature and salinity effects on the growth rate. Two organisms were successfully used in the biosensor. The preferred organism was Stenotrophomonas nitritireducens, which is an organism

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Hwang, Hye Suk, Jae Won Jeong, Yoong Ahm Kim, and Mincheol Chang. "Carbon Nanomaterials as Versatile Platforms for Biosensing Applications." Micromachines 11, no. 9 (2020): 814. http://dx.doi.org/10.3390/mi11090814.

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A biosensor is defined as a measuring system that includes a biological receptor unit with distinctive specificities toward target analytes. Such analytes include a wide range of biological origins such as DNAs of bacteria or viruses, or proteins generated from an immune system of infected or contaminated living organisms. They further include simple molecules such as glucose, ions, and vitamins. One of the major challenges in biosensor development is achieving efficient signal capture of biological recognition-transduction events. Carbon nanomaterials (CNs) are promising candidates to improve

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Rodriguez-Mozaz, S., M. P. Marco, M. J. Lopez de Alda, and D. Barceló. "Biosensors for environmental applications: Future development trends." Pure and Applied Chemistry 76, no. 4 (2004): 723–52. http://dx.doi.org/10.1351/pac200476040723.

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Biosensors can be excellent analytical tools for monitoring programs working to implement legislation. In this article, biosensors for environmental analysis and monitoring are extensively reviewed. Examples of biosensors for the most important families of envi-ronmental pollutants, including some commercial devices, are presented. Finally, future trends in biosensor development are discussed. In this context, bioelectronics, nanotechnology, miniaturization, and especially biotechnology seem to be growing areas that will have a marked influence on the development of new biosensing strategies i

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Zemerov, Serge D., and Ivan J. Dmochowski. "Cryptophane–xenon complexes for 129Xe MRI applications." RSC Advances 11, no. 13 (2021): 7693–703. http://dx.doi.org/10.1039/d0ra10765d.

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This review aims to summarize the development of cryptophane biosensors for <sup>129</sup>Xe MRI applications, while highlighting innovative biosensor designs and the consequent enhancements in detection sensitivity, which will be invaluable in expanding the scope of <sup>129</sup>Xe MRI.

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Gorodkiewicz, Ewa, and Zenon Lukaszewski. "Recent Progress in Surface Plasmon Resonance Biosensors (2016 to Mid-2018)." Biosensors 8, no. 4 (2018): 132. http://dx.doi.org/10.3390/bios8040132.

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: More than 50 papers on surface plasmon resonance biosensors, published between 2016 and mid-2018, are reviewed. Papers concerning the determination of large particles such as vesicles, exosomes, cancer cells, living cells, stem cells, and microRNA are excluded, as these are covered by a very recent review. The reviewed papers are categorized into five groups, depending on the degree of maturity of the reported solution; ranging from simple marker detection to clinical application of a previously developed biosensor. Instrumental solutions and details of biosensor construction are analyzed, i

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Sedki, Mohammed, Ying Chen, and Ashok Mulchandani. "Non-Carbon 2D Materials-Based Field-Effect Transistor Biosensors: Recent Advances, Challenges, and Future Perspectives." Sensors 20, no. 17 (2020): 4811. http://dx.doi.org/10.3390/s20174811.

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In recent years, field-effect transistors (FETs) have been very promising for biosensor applications due to their high sensitivity, real-time applicability, scalability, and prospect of integrating measurement system on a chip. Non-carbon 2D materials, such as transition metal dichalcogenides (TMDCs), hexagonal boron nitride (h-BN), black phosphorus (BP), and metal oxides, are a group of new materials that have a huge potential in FET biosensor applications. In this work, we review the recent advances and remarkable studies of non-carbon 2D materials, in terms of their structures, preparations

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Ali, Athmar A., Ammar B. Altemimi, Nawfal Alhelfi, and Salam A. Ibrahim. "Application of Biosensors for Detection of Pathogenic Food Bacteria: A Review." Biosensors 10, no. 6 (2020): 58. http://dx.doi.org/10.3390/bios10060058.

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The use of biosensors is considered a novel approach for the rapid detection of foodborne pathogens in food products. Biosensors, which can convert biological, chemical, or biochemical signals into measurable electrical signals, are systems containing a biological detection material combined with a chemical or physical transducer. The objective of this review was to present the effectiveness of various forms of sensing technologies for the detection of foodborne pathogens in food products, as well as the criteria for industrial use of this technology. In this article, the principle components

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17

Petrauskas, Karolis, and Romas Baronas. "Biojutiklių, modeliuojamų dvimatėje erdvėje, kompiuterinių modelių automatizuotas sudarymas." Informacijos mokslai 42, no. 43 (2008): 108–13. http://dx.doi.org/10.15388/im.2008.0.3434.

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Biojutikliai yra plačiai naudojami tirti medžiagų koncentracijai tirpaluose. Viena pagrindinių biojutiklio sudedamųjų dalių yra fermentas. Fermentai yra gana brangios medžiagos, dėl to ir vykdyti eksperimentus yra brangu. Kuriant naujus biojutiklius tenka atlikti daug eksperimentų. Kad būtų sumažintas reikiamų eksperimentų skaičius, taikomas kompiuterinis biojutiklių veiksmo modeliavimas. Dažniausiai konkrečios geometrijos biojutikliui kuriamas konkretus jo kompiuterinis modelis. Šiame straipsnyje pristatoma sistema, kuri gali prisitaikyti prie konkrečios geometrijos biojutiklio. Sistema gali

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18

Damborský, Pavel, Juraj Švitel, and Jaroslav Katrlík. "Optical biosensors." Essays in Biochemistry 60, no. 1 (2016): 91–100. http://dx.doi.org/10.1042/ebc20150010.

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Optical biosensors represent the most common type of biosensor. Here we provide a brief classification, a description of underlying principles of operation and their bioanalytical applications. The main focus is placed on the most widely used optical biosensors which are surface plasmon resonance (SPR)-based biosensors including SPR imaging and localized SPR. In addition, other optical biosensor systems are described, such as evanescent wave fluorescence and bioluminescent optical fibre biosensors, as well as interferometric, ellipsometric and reflectometric interference spectroscopy and surfa

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Xiang, Qian, Ying Gao, Jing Qiu Liu, et al. "Development of Nanomaterials Electrochemical Biosensor and its Applications." Advanced Materials Research 418-420 (December 2011): 2082–85. http://dx.doi.org/10.4028/www.scientific.net/amr.418-420.2082.

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Study of the electrochmeical biosensor has become a new interdisciplinary frontier between biological detection and material science due to their excellent prospects for interfacing biological recognition events with electronic signal transduction. Nanomaterials provided a significant platform for designing a new generation of bioelectronic devices exhibiting novel functions due to their high surface-to-volume ratio, good stability, small dimension effect, good compatibility and strong adsorption ability. In this paper, we review the development of electrochemical biosensors fabricated with va

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20

Kim, Ji-Yong, Yong Ju Yun, Joshua Jeong, C. Yoon Kim, Klaus-Robert Müller, and Seong-Whan Lee. "Leaf-inspired homeostatic cellulose biosensors." Science Advances 7, no. 16 (2021): eabe7432. http://dx.doi.org/10.1126/sciadv.abe7432.

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An incompatibility between skin homeostasis and existing biosensor interfaces inhibits long-term electrophysiological signal measurement. Inspired by the leaf homeostasis system, we developed the first homeostatic cellulose biosensor with functions of protection, sensation, self-regulation, and biosafety. Moreover, we find that a mesoporous cellulose membrane transforms into homeostatic material with properties that include high ion conductivity, excellent flexibility and stability, appropriate adhesion force, and self-healing effects when swollen in a saline solution. The proposed biosensor i

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21

Feng, Yingzhu, Zhangzhang Xie, Xuanlong Jiang, et al. "The Applications of Promoter-gene-Engineered Biosensors." Sensors 18, no. 9 (2018): 2823. http://dx.doi.org/10.3390/s18092823.

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A promoter is a small region of a DNA sequence that responds to various transcription factors, which initiates a particular gene expression. The promoter-engineered biosensor can activate or repress gene expression through a transcription factor recognizing specific molecules, such as polyamine, sugars, lactams, amino acids, organic acids, or a redox molecule; however, there are few reported applications of promoter-enhanced biosensors. This review paper highlights the strategies of construction of promoter gene-engineered biosensors with human and bacteria genetic promoter arrays with regard

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Zinoviev, Kirill, Laura G. Carrascosa, José Sánchez del Río, Borja Sepúlveda, Carlos Domínguez, and Laura M. Lechuga. "Silicon Photonic Biosensors for Lab-on-a-Chip Applications." Advances in Optical Technologies 2008 (June 4, 2008): 1–6. http://dx.doi.org/10.1155/2008/383927.

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In the last two decades, we have witnessed a remarkable progress in the development of biosensor devices and their application in areas such as environmental monitoring, biotechnology, medical diagnostics, drug screening, food safety, and security, among others. The technology of optical biosensors has reached a high degree of maturity and several commercial products are on the market. But problems of stability, sensitivity, and size have prevented the general use of optical biosensors for real field applications. Integrated photonic biosensors based on silicon technology could solve such draw

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Rho, Donggee, Caitlyn Breaux, and Seunghyun Kim. "Label-Free Optical Resonator-Based Biosensors." Sensors 20, no. 20 (2020): 5901. http://dx.doi.org/10.3390/s20205901.

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The demand for biosensor technology has grown drastically over the last few decades, mainly in disease diagnosis, drug development, and environmental health and safety. Optical resonator-based biosensors have been widely exploited to achieve highly sensitive, rapid, and label-free detection of biological analytes. The advancements in microfluidic and micro/nanofabrication technologies allow them to be miniaturized and simultaneously detect various analytes in a small sample volume. By virtue of these advantages and advancements, the optical resonator-based biosensor is considered a promising p

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Tan, Aaron, Candy Lim, Shui Zou, Qian Ma, and Zhiqiang Gao. "Electrochemical nucleic acid biosensors: from fabrication to application." Analytical Methods 8, no. 26 (2016): 5169–89. http://dx.doi.org/10.1039/c6ay01221c.

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This article reviews the progress in the development of electrochemical nucleic acid biosensors with an emphasis on biosensor fabrication, the sensing mechanism, performance and applications with some discussion on challenges and perspectives.

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Kunzelmann, Simone, and Martin R. Webb. "Fluorescence detection of GDP in real time with the reagentless biosensor rhodamine–ParM." Biochemical Journal 440, no. 1 (2011): 43–49. http://dx.doi.org/10.1042/bj20110349.

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The development of novel fluorescence methods for the detection of key biomolecules is of great interest, both in basic research and in drug discovery. Particularly relevant and widespread molecules in cells are ADP and GDP, which are the products of a large number of cellular reactions, including reactions catalysed by nucleoside triphosphatases and kinases. Previously, biosensors for ADP were developed in this laboratory, based on fluorophore adducts with the bacterial actin homologue ParM. It is shown in the present study that one of these biosensors, tetramethylrhodamine–ParM, can also mon

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Silina, Yuliya E., Krist V. Gernaey, Daria Semenova, and Igor Iatsunskyi. "Application of Organic-Inorganic Hybrids in Chemical Analysis, Bio- and Environmental Monitoring." Applied Sciences 10, no. 4 (2020): 1458. http://dx.doi.org/10.3390/app10041458.

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Organic-inorganic hybrids (OIH) are considered to be a powerful platform for applications in many research and industrial fields. This review highlights the application of OIH for chemical analysis, biosensors, and environmental monitoring. A methodology toward metrological traceability measurement and standardization of OIH and demonstration of the role of mathematical modeling in biosensor design are also presented. The importance of the development of novel types of OIH for biosensing applications is highlighted. Finally, current trends in nanometrology and nanobiosensors are presented.

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Hasan, Anwarul, Md Nurunnabi, Mahboob Morshed, et al. "Recent Advances in Application of Biosensors in Tissue Engineering." BioMed Research International 2014 (2014): 1–18. http://dx.doi.org/10.1155/2014/307519.

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Biosensors research is a fast growing field in which tens of thousands of papers have been published over the years, and the industry is now worth billions of dollars. The biosensor products have found their applications in numerous industries including food and beverages, agricultural, environmental, medical diagnostics, and pharmaceutical industries and many more. Even though numerous biosensors have been developed for detection of proteins, peptides, enzymes, and numerous other biomolecules for diverse applications, their applications in tissue engineering have remained limited. In recent y

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Bahl, Shashi, Ashok Kumar Bagha, Shanay Rab, Mohd Javaid, Abid Haleem, and Ravi Pratap Singh. "Advancements in Biosensor Technologies for Medical Field and COVID-19 Pandemic." Journal of Industrial Integration and Management 06, no. 02 (2021): 175–91. http://dx.doi.org/10.1142/s2424862221500081.

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World health organization (WHO) has declared the COVID-19 outbreak as a public health emergency of international concern and then as a pandemic on 30th of January and 11th of March 2020, respectively. After such concern, the world scientific communities have rushed to search for solutions to bring down the disease’s spread, fast-paced vaccine development, and associated medical research using modern technologies. Biosensor technologies play a crucial role in diagnosing various medical diseases, including COVID-19. The present paper describes the major advancement of biosensor-based technologic

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Li, Chunmei, Yihan Wang, Hui Jiang, and Xuemei Wang. "Biosensors Based on Advanced Sulfur-Containing Nanomaterials." Sensors 20, no. 12 (2020): 3488. http://dx.doi.org/10.3390/s20123488.

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In recent years, sulfur-containing nanomaterials and their derivatives/composites have attracted much attention because of their important role in the field of biosensor, biolabeling, drug delivery and diagnostic imaging technology, which inspires us to compile this review. To focus on the relationships between advanced biomaterials and biosensors, this review describes the applications of various types of sulfur-containing nanomaterials in biosensors. We bring two types of sulfur-containing nanomaterials including metallic sulfide nanomaterials and sulfur-containing quantum dots, to discuss a

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Lee, Jin-Young, Bong Hyun Sung, So-Hyung Oh, et al. "C1 Compound Biosensors: Design, Functional Study, and Applications." International Journal of Molecular Sciences 20, no. 9 (2019): 2253. http://dx.doi.org/10.3390/ijms20092253.

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The microbial assimilation of one-carbon (C1) gases is a topic of interest, given that products developed using this pathway have the potential to act as promising substrates for the synthesis of valuable chemicals via enzymatic oxidation or C–C bonding. Despite extensive studies on C1 gas assimilation pathways, their key enzymes have yet to be subjected to high-throughput evolution studies on account of the lack of an efficient analytical tool for C1 metabolites. To address this challenging issue, we attempted to establish a fine-tuned single-cell–level biosensor system constituting a combina

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Kim, Jayoung, Gabriela Valdés-Ramírez, Amay J. Bandodkar, et al. "Non-invasive mouthguard biosensor for continuous salivary monitoring of metabolites." Analyst 139, no. 7 (2014): 1632–36. http://dx.doi.org/10.1039/c3an02359a.

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A wearable mouthguard electrochemical biosensor for salivary metabolites is described. Such non-invasive mouthguard metabolite biosensors provide real-time information regarding a wearer's health, performance and stress level, and thus hold considerable promise for diverse biomedical and fitness applications.

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Su, Mingyang, Xueyu Chen, Linwei Tang, et al. "Black phosphorus (BP)–graphene guided-wave surface plasmon resonance (GWSPR) biosensor." Nanophotonics 9, no. 14 (2020): 4265–72. http://dx.doi.org/10.1515/nanoph-2020-0251.

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AbstractDue to lower out-of-plane electrical conductance, black phosphorus (BP) provides a suitable host material for improving the sensitivity of biosensors. However, BP oxidizes easily, which limits practical applications. In this article, we propose a sensitivity-enhanced guided-wave surface plasmon resonance (GWSPR) biosensor based on a BP–graphene hybrid structure. This BP–graphene hybrid structure exhibits strong antioxidation properties and exceptional biomolecule-trapping capability, which improve the stability and sensitivity of GWSPR biosensors, respectively. We show that the propose

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Valencia, Germán Ayala, Luci Cristina de Oliveira Vercik, and Andrés Vercik. "A new conductometric biosensor based on horseradish peroxidase immobilized on chitosan and chitosan/gold nanoparticle films." Journal of Polymer Engineering 34, no. 7 (2014): 633–38. http://dx.doi.org/10.1515/polyeng-2014-0072.

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Abstract A new conductometric biosensor was developed and characterized; the biosensor was based on horseradish peroxidase that was deposited in chitosan and chitosan/AuNPs films. The biosensors were characterized by scanning electron microscopy and current-voltage curves. Current-voltage curves in biosensors showed that the electrical conductivity and bistability in biosensors can be modulated by horseradish peroxidase. Horseradish peroxidase catalyzed the reduction of H2 O2 to H2 O with the oxidation of the prosthetic group (Fe3+) in the enzyme to Fe4+=O. Conductometric signal in the biosens

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Sabr, Ahmed. "Biosensor for Biomedical Applications." IARJSET 3, no. 4 (2016): 145–48. http://dx.doi.org/10.17148/iarjset.2016.3431.

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Karlsson, Olof. "Biosensor applications for biomembranes." Chemistry and Physics of Lipids 149 (September 2007): S17—S18. http://dx.doi.org/10.1016/j.chemphyslip.2007.06.038.

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Smyth, MalcolmR. "Biosensor Principles and Applications." Analytica Chimica Acta 268, no. 1 (1992): 191–92. http://dx.doi.org/10.1016/0003-2670(92)85268-b.

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Sheppard, N. F. "Biosensor principles and applications." Journal of Controlled Release 20, no. 1 (1992): 80–81. http://dx.doi.org/10.1016/0168-3659(92)90143-f.

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Çağlayan, Zeynep, Yağmur Demircan Yalçın, and Haluk Külah. "A Prominent Cell Manipulation Technique in BioMEMS: Dielectrophoresis." Micromachines 11, no. 11 (2020): 990. http://dx.doi.org/10.3390/mi11110990.

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BioMEMS, the biological and biomedical applications of micro-electro-mechanical systems (MEMS), has attracted considerable attention in recent years and has found widespread applications in disease detection, advanced diagnosis, therapy, drug delivery, implantable devices, and tissue engineering. One of the most essential and leading goals of the BioMEMS and biosensor technologies is to develop point-of-care (POC) testing systems to perform rapid prognostic or diagnostic tests at a patient site with high accuracy. Manipulation of particles in the analyte of interest is a vital task for POC and

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Norhafiezah, S., R. M. Ayub, Mohd Khairuddin Md Arshad, A. H. Azman, M. A. Farehanim та U. Hashim. "A Review of High-κ Material for Biosensor Application". Advanced Materials Research 1109 (червень 2015): 123–27. http://dx.doi.org/10.4028/www.scientific.net/amr.1109.123.

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The aim of this paper is to review several high-κ materials pertaining to their suitability as biocompatible layer in biosensor applications. The recent challenges and issues related to the process development of the stated applications were discussed. The materials were chosen based on the ideal biosensor characteristics such as biocompatibility of the material, the limit of detection, the sensitivity of the biosensor, etc. Based on our studies, TiO2thin-film has emerged as the most promising high-κ material for biosensor applications because of its excellent biocompatibility. The additional

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Cavalcante, Francisco T. T., Italo R. de A. Falcão, José E. da S. Souza, et al. "Designing of Nanomaterials-Based Enzymatic Biosensors: Synthesis, Properties, and Applications." Electrochem 2, no. 1 (2021): 149–84. http://dx.doi.org/10.3390/electrochem2010012.

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Among the many biological entities employed in the development of biosensors, enzymes have attracted the most attention. Nanotechnology has been fostering excellent prospects in the development of enzymatic biosensors, since enzyme immobilization onto conductive nanostructures can improve characteristics that are crucial in biosensor transduction, such as surface-to-volume ratio, signal response, selectivity, sensitivity, conductivity, and biocatalytic activity, among others. These and other advantages of nanomaterial-based enzymatic biosensors are discussed in this work via the compilation of

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Lai, Yeong Lin, and Chi Cheng Chiu. "Nanofabrication of Polymer Biosensor Structures for Biomedical Applications." Applied Mechanics and Materials 826 (February 2016): 155–59. http://dx.doi.org/10.4028/www.scientific.net/amm.826.155.

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This paper presents the nanofabrication of polymer biosensor structures for biomedical applications. The polymer biosensor structures were achieved using hot embossing technology. The pressure effects on the replication of patterns during the hot embossing of the polymer biosensor structures were investigated. The fabricated polymer biosensor structures with pillar arrays were applied to immunoassay biochips. The pillar shapes of the polymer biosensor structures provided large surface areas and improved the antibody-antigen interaction of the immunoassay biochips.

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VATTIPALLI, KRISHNA, PAIGE FEIKERT, SAVINDRA BRANDIGAMPALA, and SHALINI PRASAD. "STUDY OF NANOPOROUS MEMBRANES WITH APPLICATIONS IN THE ENHANCED DETECTION OF CADIOVASCULAR BIOMARKER PROTEINS." Nano LIFE 01, no. 03n04 (2010): 175–83. http://dx.doi.org/10.1142/s1793984410000213.

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The goal of this work is to understand the role of nanoconfinement in designing molecular biosensors. We have been investigating microdevices incorporated with nanoporous membranes as molecular biosensor platforms. Detection of ultra low concentration of biomolecules is the key expectation from the new class of molecular biosensors utilizing nanomaterial. In this paper we have evaluated the role of the physical attributes of nanoporous aluminum oxide membranes in nanoconfinement and enhancing sensitivity of detection of protein biomolecules. In this biosensor configuration we have generated a

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Kim, Dong Min, Jong Seong Park, Seung-Woon Jung, Jinho Yeom, and Seung Min Yoo. "Biosensing Applications Using Nanostructure-Based Localized Surface Plasmon Resonance Sensors." Sensors 21, no. 9 (2021): 3191. http://dx.doi.org/10.3390/s21093191.

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Localized surface plasmon resonance (LSPR)-based biosensors have recently garnered increasing attention due to their potential to allow label-free, portable, low-cost, and real-time monitoring of diverse analytes. Recent developments in this technology have focused on biochemical markers in clinical and environmental settings coupled with advances in nanostructure technology. Therefore, this review focuses on the recent advances in LSPR-based biosensor technology for the detection of diverse chemicals and biomolecules. Moreover, we also provide recent examples of sensing strategies based on di

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Singh, Ravindra P. "Prospects of Nanobiomaterials for Biosensing." International Journal of Electrochemistry 2011 (2011): 1–30. http://dx.doi.org/10.4061/2011/125487.

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Progress and development in biosensor development will inevitably focus upon the technology of the nanomaterials that offer promise to solve the biocompatibility and biofouling problems. The biosensors using smart nanomaterials have applications for rapid, specific, sensitive, inexpensive, in-field, on-line and/or real-time detection of pesticides, antibiotics, pathogens, toxins, proteins, microbes, plants, animals, foods, soil, air, and water. Thus, biosensors are excellent analytical tools for pollution monitoring, by which implementation of legislative provisions to safeguard our biosphere

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Asal, Melis, Özlem Özen, Mert Şahinler, Hasan Tahsin Baysal, and İlker Polatoğlu. "An overview of biomolecules, immobilization methods and support materials of biosensors." Sensor Review 39, no. 3 (2019): 377–86. http://dx.doi.org/10.1108/sr-04-2018-0084.

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Purpose Traditional analytical methods are often time-consuming and require bulky instruments, making their widespread implementation challenging. This paper aims to represent the principal concepts of biosensors as an introduction of this technology to readers and offers a comprehensive understanding of its functions. Design/methodology/approach The authors provide descriptions of the components, characteristics and advantages of biosensors along with the immobilization methods, followed by a brief discussion. Findings A biosensor is an analytical device comprising a specific biomolecule and

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Tang, Longteng, Shuce Zhang, Yufeng Zhao, et al. "Switching between Ultrafast Pathways Enables a Green-Red Emission Ratiometric Fluorescent-Protein-Based Ca2+ Biosensor." International Journal of Molecular Sciences 22, no. 1 (2021): 445. http://dx.doi.org/10.3390/ijms22010445.

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Ratiometric indicators with long emission wavelengths are highly preferred in modern bioimaging and life sciences. Herein, we elucidated the working mechanism of a standalone red fluorescent protein (FP)-based Ca2+ biosensor, REX-GECO1, using a series of spectroscopic and computational methods. Upon 480 nm photoexcitation, the Ca2+-free biosensor chromophore becomes trapped in an excited dark state. Binding with Ca2+ switches the route to ultrafast excited-state proton transfer through a short hydrogen bond to an adjacent Glu80 residue, which is key for the biosensor’s functionality. Inspired

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Rasooly, Avraham, and Keith E. Herold. "Biosensors for the Analysis of Food- and Waterborne Pathogens and Their Toxins." Journal of AOAC INTERNATIONAL 89, no. 3 (2006): 873–83. http://dx.doi.org/10.1093/jaoac/89.3.873.

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Abstract Biosensors are devices which combine a biochemical recognition element with a physical transducer. There are various types of biosensors, including electrochemical, acoustical, and optical sensors. Biosensors are used for medical applications and for environmental testing. Although biosensors are not commonly used for food microbial analysis, they have great potential for the detection of microbial pathogens and their toxins in food. They enable fast or real-time detection, portability, and multipathogen detection for both field and laboratory analysis. Several applications have been

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Chiorcea-Paquim, Ana-Maria, and Ana Maria Oliveira-Brett. "DNA Electrochemical Biosensors for In Situ Probing of Pharmaceutical Drug Oxidative DNA Damage." Sensors 21, no. 4 (2021): 1125. http://dx.doi.org/10.3390/s21041125.

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Deoxyribonucleic acid (DNA) electrochemical biosensors are devices that incorporate immobilized DNA as a molecular recognition element on the electrode surface, and enable probing in situ the oxidative DNA damage. A wide range of DNA electrochemical biosensor analytical and biotechnological applications in pharmacology are foreseen, due to their ability to determine in situ and in real-time the DNA interaction mechanisms with pharmaceutical drugs, as well as with their degradation products, redox reaction products, and metabolites, and due to their capacity to achieve quantitative electroanaly

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Rzhevskii, Alexander. "The Recent Advances in Raman Microscopy and Imaging Techniques for Biosensors." Biosensors 9, no. 1 (2019): 25. http://dx.doi.org/10.3390/bios9010025.

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Raman microspectroscopy is now well established as one of the most powerful analytical techniques for a diverse range of applications in physical (material) and biological sciences. Consequently, the technique provides exceptional analytical opportunities to the science and technology of biosensing due to its capability to analyze both parts of a biosensor system—biologically sensitive components, and a variety of materials and systems used in physicochemical transducers. Recent technological developments in Raman spectral imaging have brought additional possibilities in two- and three-dimensi

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Górski, Łukasz, Kamil F. Trzebuniak, and Malinowska Elżbieta. "Low Bod Determination Methods: The State-of-the-Art." Chemical and Process Engineering 33, no. 4 (2012): 629–37. http://dx.doi.org/10.2478/v10176-012-0053-7.

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Biochemical Oxygen Demand (BOD) is an important factor used to measure water pollution. This article reviews recent developments of microbial biosensors with respect to their applications for low BOD estimation. Four main methods to measure BOD using a biosensor are described: microbial fuel cells, optical methods, oxygen electrode based methods and mediator-based methods. Each of them is based on different principles, thus a different approach is required to improve the limit of detection. A proper choice of microorganisms used in the biosensor construction and/or sample pre-treatment process

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