Relevant bibliographies by topics / Biosensors Surface plasmon resonance / Dissertations / Theses
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Dissertations / Theses on the topic 'Biosensors Surface plasmon resonance'

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Published: 4 June 2021
Last updated: 1 February 2022

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1

Nenninger, Garet Glenn. "High-resolution surface plasmon resonance biosensing /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/5840.

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2

Lu, Hongbo. "Surface plasmon resonance biosensors : development and applications /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/8069.

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3

Chinowsky, Timothy Mark. "Optical multisensors based on surface plasmon resonance /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/5857.

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4

Liley, Martha Jane. "Surface plasmon resonance for the detection of DNA hybridisation." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357824.

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5

Wijaya, Edy. "Design and optimization of Surface Plasmon Resonance (SPR) biosensors." Thesis, Lille 1, 2012. http://www.theses.fr/2012LIL10096/document.

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En terme de performance, le biocapteur idéal doit avoir très grande sensibilité, basse limite de détection et temps d’analyse qui est extrêmement court. Les biocapteurs sans marquage à base de résonance de plasmons de surface (biocapteurs SPR) possèdent naturellement le temps d’analyse le plus court parmi différent types de biocapteurs. Leur limite de détection n’est cependant pas la plus impressionnante. Il y a donc un besoin pour augmenter considérablement la sensibilité intrinsèque des biocapteurs SPR afin de permettre de plus basses limites de détection. Quelques approches pour exalter la
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6

Sabot, Andrea. "Chemical sensing with ultrathin organic films using surface plasmon resonance." Thesis, University of Sheffield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301904.

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7

Sommers, Daniel R. "Design and verification of a surface plasmon resonance biosensor." Available online, Georgia Institute of Technology, 2004, 2003. http://etd.gatech.edu/theses/available/etd-08172004-091020/unrestricted/sommers%5Fdaniel%5Fr%5F200505%5Fmast.pdf.

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Thesis (M. S.)--Bioengineering, Georgia Institute of Technology, 2004.<br>William D. Hunt, Committee Chair ; Allen M. Orville, Committee Member ; Cheng Zhu, Committee Member ; Doug Armstrong, Committee Member ; Lawrence A. Bottomley, Committee Member. Includes bibliographical references.
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8

Jungar, Christina. "Affinity biosensors for carbohydrate-protein interactions using surface plasmon resonance /." Linköping : Univ, 2001. http://www.bibl.liu.se/liupubl/disp/disp2001/tek701s.pdf.

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9

Harris, Richard David. "Waveguide surface plasmon resonance biosensor." Thesis, University of Southampton, 1996. https://eprints.soton.ac.uk/398739/.

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This thesis reports the design and development of the first waveguide surface plasmon resonance (SPR) biosensor for pesticide analysis. The integrated optical format allows the fabrication of a compact sensor that may be connected to optical fibre; necessary steps towards a portable optical biosensor. A major advantage of the integrated optical approach is the possibility of fabricating multiple sensors on one substrate, and hence testing for multiple analytes in one basic assay. The SPR structure incorporates a metal film that may be employed as an electrode to study the electrochemical contr
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10

Sommers, Daniel R. "Design and verification of a surface plasmon resonance biosensor." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/6967.

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The Microelectronics Group has been researching sensors useful for detecting and quantifying events in biological molecular chemistry, for example, binding events. Our previous research has been based primarily on quartz resonators. This thesis describes the results of our initial research of Surface Plasmon Resonance (SPR) based technology. This study contains the design and implementation of a fully functional SPR biosensor with detailed disclosure of monolayer construction, digital hardware interfaces and software algorithms for process the SPR sensors output. An antibody monolayer was c
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11

Cao, Jie. "Creation of novel gold-nanorod-based localized surface plasmon resonance biosensors." Thesis, City University London, 2013. http://openaccess.city.ac.uk/2990/.

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Starting with a comprehensive review of both surface plasmon resonance (SPR) based and localized surface plasmon resonance (LSPR) based sensors, this thesis reports the studies on the development of a novel sensitive gold nanorod (GNR) based label-free LSPR optical fibre biosensor, and the development of a novel robust method for effectively modifying the surface of cetyl-trimethyl ammonium bromide (CTAB) capped GNRs and their LSPR biosensing applications. A novel GNR-based LSPR optical fibre sensor was fabricated and evaluated in this work. The sensor probe was prepared by covalently immobili
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12

Liu, Chang. "Localized Surface Plasmon Resonance Biosensors for Real-Time Biomolecular Binding Study." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/837.

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Surface Plasmon Resonance (SPR) and localized surface plasmon resonance (LSPR) biosensors have brought a revolutionary change to in vitro study of biological and biochemical processes due to its ability to measure extremely small changes in surface refractive index (RI), binding equilibrium and kinetics. Strategies based on LSPR have been employed to enhance the sensitivity for a variety of applications, such as diagnosis of diseases, environmental analysis, food safety, and chemical threat detection. In LSPR spectroscopy, absorption and scattering of light are greatly enhanced at frequencies
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13

Du, Yao. "Particle-modified surface plasmon resonance biosensor." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/289388.

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Surface plasmon resonance (SPR) biosensors have attracted great attention in scientific research in the past three decades. Extensive studies on the immobilisation of biorecognition elements have been conducted in pursuit of higher sensitivity, but trialled formats have focussed on a thin layer modification next to the plasmon film, which usually requires in situ derivatization. This thesis investigates an 'off-chip' immobilisation strategy for SPR biosensing using silica particles and considers the implications of a particle-modified evanescent field on the signal amplitude and kinetics, for
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14

Ou, Meigui. "Nanostructured gold surfaces as biosensors : surface-enhanced chemiluminescence and double detection by surface plasmon resonance and luminescence." Lyon, INSA, 2008. http://theses.insa-lyon.fr/publication/2008ISAL0057/these.pdf.

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This thesis is devoted to develop two biological detection systems based on nanostructured gold surfaces to detect the binding of streptavidin/biotin. In the first part, we have studied a multimodal detection system using local surface plasmon resonance of the gold substrate and the luminescence of labelling core-shell Gd2O3/SiOx nanoparticles, which profits from the plasmonic property of nanostructure gold. In a second part, we have focused in a surface-enhanced chemiluminescence system based on chemiluminescence of luminal/hydrogen peroxide (H2O2) enhanced by gold nanostructures in the vicin
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15

Sapsford, Kim Elizabeth. "The development of optical biosensors for nitrogen oxyanions using metalloproteins." Thesis, University of East Anglia, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327497.

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16

Wathen, Adam D. "An Exploration of Electron-Excited Surface Plasmon Resonance for Use In Biosensor Applications." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/5240.

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Electron-excited surface plasmon resonance (eSPR) is investigated for potential use in biosensors. Optical SPR sensors are commercially available at present and these sensors are extremely sensitive, but have the tendency to be relatively large, expensive, and ignore the potentials of microelectronic technology. By employing the use of various microelectronic and nanotechnology principles, the goal is to eventually design a device that exploits the eSPR phenomenon in order to make a sensor which is siginificantly smaller in size, more robust, and cheaper in cost.
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17

Wei, Dong. "Development of a surface plasmon resonance biosensor for the identification of Campylobacter jejuni." Auburn, Ala, 2006. http://repo.lib.auburn.edu/2006%20Summer/Theses/WEI_DONG_0.pdf.

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18

Canelle, Quentin. "Real Time Surface Plasmon Resonance Biosensors, a Powerful Technology to Assess Polyclonal Antibody Avidity." Doctoral thesis, Universite Libre de Bruxelles, 2015. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/216754.

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The present research focused on the development of a new methodology to assess the strength of the interaction between vaccine antigens and elicited polyclonal antibodies through SPR biosensors. Quantifying the binding strength of polyclonal antibodies is of first importance to evaluate the quality of the vaccine as well as to increase the scientific knowledge of immune protection mechanisms. To now the development of such tool has been complicated by the non-specific binding caused by high protein abundance in the blood and serum samples but also by the way of interpreting the data resulting
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19

See, Erich Michael. "Modeling Plasmon Resonance for a Gold Nanoparticle Plasmon-Enhanced Cadmium Sulfide Biosensor." Miami University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=miami1249499557.

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20

Earp, Ronald Lee Jr. "Multiwavelength Surface Plasmon Resonance Sensor Designs for Chemical and Biochemical Detection." Diss., Virginia Tech, 1998. http://hdl.handle.net/10919/30581.

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Surface plasmon resonance (SPR) sensors using multiwavelength light coupling are investigated to probe changes in refractive index that occur as a result of chemical or biochemical processes. Traditional SPR sensors have used angle modulation to facilitate detection at the sensor surface; however, the multiwavelength approach is novel and brings new functionality to SPR sensors. The multiwavelength sensors are constructed on both fiber optic and bulk waveguides such as prisms. A thin metal film is deposited on the waveguide surface to support the surface plasmon (SP) mode. The evanescent
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21

Nygren, Babol Linnéa. "Folate binding protein in bovine milk : occurrence and properties studied with surface plasmon resonance /." Uppsala : Dept. of Food Science, Swedish University of Agricultural Sciences, 2007. http://epsilon.slu.se/2007102.pdf.

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22

Sanchez, Erik De Jesus. "Modeling of the Surface Plasmon Resonance (SPR) Effect for a Metal-Semiconductor (M-S) Junction at Elevated Temperatures." PDXScholar, 1993. https://pdxscholar.library.pdx.edu/open_access_etds/4624.

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The effect of temperature increase on the optical excitation of Surface Plasmon Resonance (SPR) at an Ag-Si metal-semiconductor (M-S) junction at a wavelength of 1 . 1 52 pm is investigated theoretically using computer modeling in Fortran. In order to accurately quantify the SPR, the temperature dependent optical constants for Ag and Si are obtained theoretically or semiempirically , using a Drude model for Ag and previous experimentally determined equations for Si (the behavior of the optical constants for crystalline Si and doped Si are found to have very little deviation between each other
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23

Nehru, Neha. "Reference Compensation for Localized Surface-Plasmon Resonance Sensors." UKnowledge, 2014. http://uknowledge.uky.edu/ece_etds/41.

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Noble metal nanoparticles supporting localized surface plasmon resonances (LSPR) have been extensively investigated for label free detection of various biological and chemical interactions. When compared to other optical sensing techniques, LSPR sensors offer label-free detection of biomolecular interactions in localized sensing volume solutions. However, these sensors also suffer from a major disadvantage – LSPR sensors remain highly susceptible to interference because they respond to both solution refractive index change and non-specific binding as well as specific binding of the target anal
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24

Bathae, Kumaresh Prasanth. "OPTIMIZATION OF A DUAL-MODE SURFACE PLASMON RESONANCE SENSOR." UKnowledge, 2007. http://uknowledge.uky.edu/gradschool_theses/424.

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Surface plasmon waves are TM polarized charge density waves that propagate at the interface of two media with real dielectric constants of opposite sign (i.e. liquid dielectric and certain metals). Surface plasmon resonance (SPR) sensors use these waves to detect refractive index changes adjacent to the metal layer. Refractive index changes arise from the binding of an analyte (e.g. a target molecule, protein, or bacterium) to the functionalized metal layer or from interfering effects such as changes in solution index. Standard, single channel SPR sensors cannot differentiate these two effects
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25

Guo, Jing. "MULTI-MODE SELF-REFERENCING SURFACE PLASMON RESONANCE SENSORS." UKnowledge, 2013. http://uknowledge.uky.edu/ece_etds/13.

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Surface-plasmon-resonance (SPR) sensors are widely used in biological, chemical, medical, and environmental sensing. This dissertation describes the design and development of dual-mode, self-referencing SPR sensors supporting two surface-plasmon modes (long- and short-range) which can differentiate surface binding interactions from bulk index changes at a single sensing location. Dual-mode SPR sensors have been optimized for surface limit of detection (LOD). In a wavelength interrogated optical setup, both surface plasmons are simultaneously excited at the same location and incident angle but
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26

Nordström, Helena. "Fragment Based Drug Discovery with Surface Plasmon Resonance Technology." Doctoral thesis, Uppsala universitet, Biokemi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-209136.

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Fragment based drug discovery (FBDD) has been applied to two protease drug targets, MMP-12 and HIV-1 protease. The primary screening and characterization of hit fragments were performed with surface plasmon resonance -technology. Further evaluation of the interaction was done by inhibition studies and in one case with X-ray crystallography. The focus of the two projects was different. Many MMP inhibitors contain a strong zinc chelating group, hydroxamate, interacting with the catalytic zinc atom. This strategy may be the cause for the low specificity of MMP inhibitors. Using FBDD we found a fr
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27

Unser, Sarah A. "Improving the Sensitivity and Selectivity of Localized Surface Plasmon Resonance Biosensors Toward Novel Point-of-Care Diagnostics." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1561997005551383.

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28

Akowuah, E. K. "Design and analysis of novel photonic crystal fibre and waveguide surface plasmon resonance biosensors operating in aqueous environments." Thesis, University of Kent, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590071.

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Surface plasmon resonance (SPR) sensors provide high sensitivity without the use of molecular labels. Most commercial SPR biosensors are based on the simple, robust and highly sensitive traditional prism-coupled configuration. However, they are not amenable to miniaturization and integration. This has led to a growing interest in the development of robust, portable and highly sensitive SPR sensing devices capable of out of laboratory measurements. This thesis covers the modelling of these sensors, using the full vectorial finite element and the eigenmode expansion methods with the aim of optim
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Gongora, Renan. "Theoretical Tailoring of Perforated Thin Silver Films for Surface Plasmon Resonance Affinity." Honors in the Major Thesis, University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1543.

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Metallic films, in conjunction with biochemical-targeted probes, are expected to provide early diagnosis, targeted therapy and non-invasive monitoring for epidemiology applications [1-4]. The resonance wavelength peaks, both plasmonic and Wood-Rayleigh Anomalies (WRAs), in the scattering spectra are affected by the metallic architecture. As of today, much research has been devoted to extinction efficiency in the plasmonic region. However, Wood Rayleigh Anomalies (WRAs) typically occur at wavelengths associated with the periodic distance of the structures. A significant number of papers have al
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30

Bang, Hyungseok. "INTEGRATED OPTICAL SPR (SURFACE PLASMON RESONANCE) SENSOR BASED ON OPTOELECTRONIC PLATFORM." Doctoral diss., University of Central Florida, 2008. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3289.

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Current major demands in SPR sensor development are system miniaturization and throughput improvement. Structuring an array of integrated optical SPR sensor heads on a semiconductor based optoelectronic platform could be a promising solution for those issues, since integrated optical waveguides have highly miniaturized dimension and the optoelectronic platform enables on-chip optical-to-electrical signal conversion. Utilizing a semiconductor based platform to achieve optoelectronic functionality poses requirements to the senor head; the sensor head needs to have reasonably small size while it
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31

Keathley, Phillip Donald. "DESIGN AND ANALYSIS OF NANO-GAP ENHANCED SURFACE PLASMON RESONANCE SENSORS." UKnowledge, 2009. http://uknowledge.uky.edu/gradschool_theses/643.

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Surface plasmon resonance (SPR) sensors are advantageous to other techniques of sensing chemical binding, offering quantitative, real-time, label-free results. Previous work has demonstrated the effectiveness of using dual-mode SPR sensors to differentiate between surface and background effects, making the sensors more robust to dynamic environments. This work demonstrates a technique that improves upon a previously optimized planar film dual-mode SPR sensor’s LOD by introducing a periodic array of subwavelength nano-gaps throughout the plasmon supporting material. First, general figures of me
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32

Chang, Sehoon. "Organic/inorganic hybrid nanostructures for chemical plasmonic sensors." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/39545.

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The work presented in this dissertation suggests novel design of chemical plasmonic sensors which have been developed based on Localized Surface Plasmon Resonance (LSPR), and Surface-enhanced Raman scattering (SERS) phenomena. The goal of the study is to understand the SERS phenomena for 3D hybrid (organic/inorganic) templates and to design of the templates for trace-level detection of selected chemical analytes relevant to liquid explosives and hazardous chemicals. The key design criteria for the development of the SERS templates are utilizing selective polymeric nanocoatings within cylindr
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33

Carvalho, Gomes Paula Alexandra de. "Surface plasmon resonance as a tool in the functional analysis of an immunodominant site in foot-and-mouth disease virus." Doctoral thesis, Universitat de Barcelona, 2000. http://hdl.handle.net/10803/2793.

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A fast and direct surface plasmon resonance (SPR) method for the kinetic analysis of the interactions between peptide antigens and immobilised monoclonal antibodies (mAb) has been established. Protocols have been developed to overcome the problems posed by the small size of the analytes (< 1600 Da). The interactions were well described by a simple 1:1 bimolecular interaction and the rate constants were self-consistent and reproducible. The key features for the accuracy of the kinetic constants measured were high buffer flow rates, medium antibody surface densities and high peptide concentratio
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34

Filion, Côté Sandrine. "Spectro-angular optical biosensor based on surface plasmon resonance operating in the visible spectrum." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106424.

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Surface plasmon resonance (SPR) is one of the most widely used methods to implement biosensors because of its label-free and sensitive detection. Surface plasmon resonance allows the change in the refractive index of a sample to be measured accurately by the analysis of the light reflecting at a metal-dielectric interface. A way to increase the sensitivity of SPR biosensors was found in fabricating a spectro-angular SPR biosensor and using of a newly developed data processing method called the Double Projection Method. The objective of the work presented in this thesis is to improve further th
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35

Barrett, G. "Towards detection of endotoxin in high-purity water utilising a surface plasmon resonance biosensor." Thesis, Cranfield University, 2000. http://dspace.lib.cranfield.ac.uk/handle/1826/11094.

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The aims of this project were to develop a system for monitoring a continuous stream of high grade purified water for potential contamination by bacterial endotoxins. The monitoring system was to be designed so that it could be readily integrated within a closed water purification processing system. The project was viewed as a developmental stage towards the development of a commercial sensor with wide ranging applications within the pharmaceutical and environmental sectors. This text details the development of testing protocols for the examination of ultra pure water using different sensing m
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Barrett, Gary. "Towards detection of endotoxin in high-purity water utilising a surface plasmon resonance biosensor." Thesis, Cranfield University, 2000. http://dspace.lib.cranfield.ac.uk/handle/1826/11094.

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The aims of this project were to develop a system for monitoring a continuous stream of high grade purified water for potential contamination by bacterial endotoxins. The monitoring system was to be designed so that it could be readily integrated within a closed water purification processing system. The project was viewed as a developmental stage towards the development of a commercial sensor with wide ranging applications within the pharmaceutical and environmental sectors. This text details the development of testing protocols for the examination of ultra pure water using different sensing m
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37

Torrance, David. "Influence of the Local Dielectric Environment and its Spatial Symmetry on Metal Nanoparticle Surface Plasmon Resonances." Honors in the Major Thesis, University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1195.

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This item is only available in print in the UCF Libraries. If this is your Honors Thesis, you can help us make it available online for use by researchers around the world by following the instructions on the distribution consent form at http://library.ucf.edu/Systems/DigitalInitiatives/DigitalCollections/InternetDistributionConsentAgreementForm.pdf You may also contact the project coordinator, Kerri Bottorff, at kerri.bottorff@ucf.edu for more information.<br>Bachelors<br>Sciences<br>Physics
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38

Singh, Meenakshi. "Nanostructured bioarchitectures for electrochemical and optical biosensor applications : design of a biocathode for biofuel cells." Thesis, Grenoble, 2014. http://www.theses.fr/2014GRENI107/document.

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Les avancées dans le domaine de l'analyse médicale et environnementale exigent des méthodes sensibles et précises pour la détection de molécules organiques nocives. Les travaux de recherche de cette thèse présentent un nouveau système d'affinité pour l'immobilisation de biorécepteurs, de nouvelles stratégies d'amplification du signal et de nouveaux nanomatériaux à base de modèles bio-inspirés afin d'améliorer les performances des biocapteurs ou des biopiles.Dans une première partie, un nouveau système d'affinité supramoléculaire entre la biotine et la beta-cyclodextrine a été étudié et a permi
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39

Balasubramanian, Shankar Ganesh Sokkalinga Simonian Aleksandr L. "Development of smart functional surfaces for biosensor applications." Auburn, Ala, 2008. http://repo.lib.auburn.edu/EtdRoot/2008/FALL/Materials_Engineering/Dissertation/Balasubramania_S%20G_2.pdf.

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Thesis (Ph. D.)--Auburn University, 2008.<br>Abstract. Vita. The following patent resulted from the dissertation research: Davis, V., Simonian, A.L., Nepal, D., Balasubramanian, S, "Preparation of Precisely Controlled Thin Film Nanocomposites of Carbon Nanotubes and Biomaterials", U.S. Provisional Patent Application No. 61/000,938, filed on 30 October 2007. The following peer-reviewed publications resulted from the dissertation research: Dhriti Nepal, Shankar Balasubramanian, Aleksandr Simonian, and Virginia Davis, "Mechanically Strong Antibacterial Thin Film Based on Single-Walled Carbon Nano
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40

Danilov, Artem. "Design, characterisation and biosensing applications of nanoperiodic plasmonic metamaterials." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0110/document.

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Cette thèse considère de nouvelles architectures prometteuses des métamatériaux plasmoniques pour biosensing, comprenant: (I) des réseaux périodiques 2D de nanoparticules d'Au, qui peuvent supporter des résonances des réseaux de surface couplées de manière diffractive; (II) Reseaux 3D à base de cristaux plasmoniques du type d'assemblage de bois. Une étude systématique des conditions d'excitation plasmonique, des propriétés et de la sensibilité à l'environnement local dans ces géométries métamatérielles est présentée. On montre que de tels réseaux peuvent combiner une très haute sensibilité spe
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41

"Surface plasmon enhanced effects in photonic biosensors." Thesis, 2008. http://library.cuhk.edu.hk/record=b6074665.

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Detection of oligonucleotide target has been performed with a sandwich assay scheme. We compare the detection performance of strategies using probe oligonucleotide with or without gold nanoparticles (Au-NPs, 20nm) capped on 3'. Our experimental results reveal that while the DNA detection implemented with NIS can provide high sensitivity, both dynamic range and detection limit can be amplified with the aid of Au-NPs on 3' of the probes. The current detection limits of NIS with and without Au-NPs are 0.4 femtomole and 1 nanomole respectively. (Abstract shortened by UMI.)<br>Finally, this work pr
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42

Luo, Yu-Tang, and 羅鈺棠. "Stabilization of nitride-base surface plasmon resonance biosensors." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/yb3z8k.

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碩士<br>國立中央大學<br>光電科學與工程學系<br>107<br>The surface plasma biosensor built with nitride quantum wells (QWs) is of many advantages, including simplified structure and enhanced sensitivity. Although the surface plasma resonance (SPR) phenomenon induced by Ag on blue-emitting QWs can achieve high enhancement in photoluminescence (PL) spectrum intensity, the instability of Ag hinders the practical applications. In this study, we investigated various structures to stabilize the Ag layer. In addition, we applied different annealing and alloying conditions in the device fabrication. It is found that the
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43

Wu, Sheng-Hung, and 吳昇紘. "Development of Disposable Localized Surface Plasmon Resonance Biosensors." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/51545500391791637000.

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44

Joe, Shen-Fen, and 卓聖芬. "Surface plasmon resonance biosensor." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/34126801039058146358.

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博士<br>國防大學中正理工學院<br>國防科學研究所<br>95<br>Surface plasmon resonance (SPR) is a collective oscillation of electrons in the surface of the metal. It is sensitive to the changes of the dielectric medium near the metal surface and can be used to detect the refractive index of the medium. In this dissertation, a biosensor combined with the common path heterodyne interferometry and the SPR technique is developed. The phase difference of the reflected light between TM and TE waves from the sensor chip is measured. To construct this high sensitive SPR biosensor system, a heterodyne light source is adopted
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45

Huang, Kai-Lin, and 黃凱麟. "Theoretical Analyses on Nitride-based Surface Plasmon Resonance Biosensors." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/24512406121164024611.

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碩士<br>國立中央大學<br>光電科學與工程學系<br>105<br>Surface plasmon resonance (SPR) is the collective electron oscillation at the interface of metal and dielectric material. The SPR effect is highly sensitive to the change of surface refractive index, and therefore can be used to detect biomolecular binding events between the antibody and the antigen. In this research, we present theoretical analyses on the potential of nitride-based SPR structure in biosensing applications. The SPR effect is achieved with a GaN/InGaN/GaN quantum well and a thin Ag layer, and the change in surface refractive index is detected
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"Surface plasmon resonance photonic biosensors based on phase-sensitive measurement techniques." 2005. http://library.cuhk.edu.hk/record=b5892392.

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Law Wing Cheung.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2005.<br>Includes bibliographical references.<br>Abstracts in English and Chinese.<br>Abstract --- p.I<br>Acknowledgements --- p.V<br>List of Publications related to this project --- p.VI<br>Contents --- p.VII<br>Chapter Chapter 1 --- Introduction --- p.1-1<br>Chapter Chapter 2 --- Literature Review<br>Chapter 2.1 --- Surface Plasmon Waves --- p.2-2<br>Chapter 2.2 --- Excitation of Surface Plasmon --- p.2-4<br>Chapter 2.2.1 --- Surface Plasmon Coupling Schemes --- p.2-6<br>Chapter 2.3 --- Detection Techniques used i
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Huang, Teng-Yi, and 黃騰毅. "Development of Graphene Oxide Sheets for Surface Plasmon Resonance Biosensors." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/68131920134228431119.

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碩士<br>國立臺灣師範大學<br>光電科技研究所<br>101<br>The advantage of surface plasmon resonance (SPR) biosensors includes high sensitivity, label-free, and real-time detection. These advantage leading SPR biosensors to identified as one of the most important optical detection methods for biomolecules. The goal of this thesis is to develop graphene oxide (GO) sheets SPR biosensor that used GO as sensing layer for biomolecules detection. First, we used cystamine as linker layer, forming Cys film by self-assembled monolayer (SAM) technique. Then, GO solution was immobilized on the surface of Cys film through c
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Chien, Fan-Ching, and 簡汎清. "Design and fabrication of ultrahigh-resolution surface plasmon resonance biosensors." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/44460806366531252281.

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碩士<br>國立中央大學<br>機械工程研究所<br>91<br>Theoretically, simulate and compare the sensitivity of any mode of the existing thin film surface plasmon resonance (SPR) biosensors. No matter which mode of the existing thin film SPR biosensors such as convential SPR biosesor, couple plasmon-waveguide resonance (CPWR) biosesor, and long-range surface plasmon resonance (LRSPR) biosesor, the detection resolution is limited to approximately 1 pg/mm2 of biomolecular surface coverage. Under this constrain, small biomolecular interactions in low concentration are hard to be analyzed. Hence, by increasing the
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Zhao, Sandy Shuo. "Detection of methotrexate using surface plasmon resonance biosensors for chemotherapy monitoring." Thèse, 2013. http://hdl.handle.net/1866/10792.

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Le méthotrexate (MTX), un agent anti-cancéreux fréquemment utilisé en chimiothérapie, requiert généralement un suivi thérapeutique de la médication (Therapeutic Drug Monitoring, TDM) pour surveiller son niveau sanguin chez le patient afin de maximiser son efficacité tout en limitant ses effets secondaires. Malgré la fenêtre thérapeutique étroite entre l’efficacité et la toxicité, le MTX reste, à ce jour, un des agents anti-cancéreux les plus utilisés au monde. Les techniques analytiques existantes pour le TDM du MTX sont coûteuses, requièrent temps et efforts, sans nécessairement fournir promp
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Fan, Shi-Yuan, and 范仕遠. "Ultra Sensitivity of Carboxylated Graphene Oxide for Surface Plasmon Resonance Biosensors." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/9sgx8z.

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碩士<br>國立臺灣師範大學<br>光電科技研究所<br>105<br>In this paper we proved that carboxyl-functionalized graphene oxide (GO-COOH) was used to detect pancreatic cancer indicator protein 19-9 with surface plasmon resonance (SPR) (Carbohydrate Antigen, CA19-9). We compare the sensitivity of GO-COOH biosensor、GO biosensor and traditional biosensor with bovine serum albumin. Next to detected CA19-9 by the highest sensitivity of GO-COOH biosensor. GO-COOH, graphene oxide (GO) and graphene were discussed with conductivity、SPR angular displacement sensitivity (S_RI) and adsorption efficiency of biomolecules. GO-COOH
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