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1

Hua, Yu, Jiaming Ma, Dachao Li, and Ridong Wang. "DNA-Based Biosensors for the Biochemical Analysis: A Review." Biosensors 12, no. 3 (2022): 183. http://dx.doi.org/10.3390/bios12030183.

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In recent years, DNA-based biosensors have shown great potential as the candidate of the next generation biomedical detection device due to their robust chemical properties and customizable biosensing functions. Compared with the conventional biosensors, the DNA-based biosensors have advantages such as wider detection targets, more durable lifetime, and lower production cost. Additionally, the ingenious DNA structures can control the signal conduction near the biosensor surface, which could significantly improve the performance of biosensors. In order to show a big picture of the DNA biosensor
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Schackart, Kenneth E., and Jeong-Yeol Yoon. "Machine Learning Enhances the Performance of Bioreceptor-Free Biosensors." Sensors 21, no. 16 (2021): 5519. http://dx.doi.org/10.3390/s21165519.

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Since their inception, biosensors have frequently employed simple regression models to calculate analyte composition based on the biosensor’s signal magnitude. Traditionally, bioreceptors provide excellent sensitivity and specificity to the biosensor. Increasingly, however, bioreceptor-free biosensors have been developed for a wide range of applications. Without a bioreceptor, maintaining strong specificity and a low limit of detection have become the major challenge. Machine learning (ML) has been introduced to improve the performance of these biosensors, effectively replacing the bioreceptor
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Turdean, Graziella L. "Design and Development of Biosensors for the Detection of Heavy Metal Toxicity." International Journal of Electrochemistry 2011 (2011): 1–15. http://dx.doi.org/10.4061/2011/343125.

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Many compounds (including heavy metals, HMs) used in different fields of industry and/or agriculture act as inhibitors of enzymes, which, as consequence, are unable to bind the substrate. Even if it is not so sensitive, the method for detecting heavy metal traces using biosensors has a dynamic trend and is largely applied for improving the “life quality”, because of biosensor's sensitivity, selectivity, and simplicity. In the last years, they also become more and more a synergetic combination between biotechnology and microelectronics. Dedicated biosensors were developed for offline and online
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Štukovnik, Zala, Regina Fuchs-Godec, and Urban Bren. "Nanomaterials and Their Recent Applications in Impedimetric Biosensing." Biosensors 13, no. 10 (2023): 899. http://dx.doi.org/10.3390/bios13100899.

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Impedimetric biosensors measure changes in the electrical impedance due to a biochemical process, typically the binding of a biomolecule to a bioreceptor on the sensor surface. Nanomaterials can be employed to modify the biosensor’s surface to increase the surface area available for biorecognition events, thereby improving the sensitivity and detection limits of the biosensor. Various nanomaterials, such as carbon nanotubes, carbon nanofibers, quantum dots, metal nanoparticles, and graphene oxide nanoparticles, have been investigated for impedimetric biosensors. These nanomaterials have yielde
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5

Generalov, Vladimir, Anastasia Cheremiskina, Alexander Glukhov, Victoria Grabezhova, Margarita Kruchinina, and Alexander Safatov. "Investigation of Limitations in the Detection of Antibody + Antigen Complexes Using the Silicon-on-Insulator Field-Effect Transistor Biosensor." Sensors 23, no. 17 (2023): 7490. http://dx.doi.org/10.3390/s23177490.

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The SOI-FET biosensor (silicon-on-insulator field-effect transistor) for virus detection is a promising device in the fields of medicine, virology, biotechnology, and the environment. However, the applications of modern biosensors face numerous problems and require improvement. Some of these problems can be attributed to sensor design, while others can be attributed to technological limitations. The aim of this work is to conduct a theoretical investigation of the “antibody + antigen” complex (AB + AG) detection processes of a SOI-FET biosensor, which may also solve some of the aforementioned
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Damborský, Pavel, Juraj Švitel, and Jaroslav Katrlík. "Optical biosensors." Essays in Biochemistry 60, no. 1 (2016): 91–100. http://dx.doi.org/10.1042/ebc20150010.

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Optical biosensors represent the most common type of biosensor. Here we provide a brief classification, a description of underlying principles of operation and their bioanalytical applications. The main focus is placed on the most widely used optical biosensors which are surface plasmon resonance (SPR)-based biosensors including SPR imaging and localized SPR. In addition, other optical biosensor systems are described, such as evanescent wave fluorescence and bioluminescent optical fibre biosensors, as well as interferometric, ellipsometric and reflectometric interference spectroscopy and surfa
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Teh, Yijun, Asral Bahari Jambek, and Uda Hashim. "The latest trend in nano-bio sensor signal analysis." Sensor Review 36, no. 3 (2016): 303–11. http://dx.doi.org/10.1108/sr-08-2015-0132.

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Purpose This paper aims to discuss a nanoscale biosensor and its signal analysis algorithms. Design/methodology/approach In this work, five nanoscale biosensors are reviewed, namely, silicon nanowire field-effect-transistor biosensors, polysilicon nanogap capacitive biosensors, nanotube amperometric biosensors, gold nanoparticle-based electrochemical biosensors and quantum dot-based electrochemical biosensors. Findings Each biosensor produces a different output signal depending on its electrical characteristics. Five signal analysers are studied, with most of the existing signal analyser analy
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Wang, Yunjie. "Application of Electrochemical Biosensors for Chemical Hazards Detection." Highlights in Science, Engineering and Technology 3 (July 8, 2022): 1–7. http://dx.doi.org/10.54097/hset.v3i.686.

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Electrochemical biosensor is a subject that has received the most attention from scientists in recent years. It is not only related to human life but also natural environment. Research on electrochemical biosensors is also cross-linked with many other scientific fields, such as nanomaterials and hazardous chemical detection. In this research, electrochemical biosensor is discussed by divided into three types, including potentiometric, amperometric, and voltammetric biosensors. The unique mechanism, advantages and application of these electrochemical biosensors is also introduced in this articl
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9

Chowdhury, Dibyendu, Bishnu Prasad De, Bhargav Appasani, et al. "A Novel Dielectric Modulated Gate-Stack Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistor-Based Sensor for Detecting Biomolecules." Sensors 23, no. 6 (2023): 2953. http://dx.doi.org/10.3390/s23062953.

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In this article, the performance of n-type junctionless (JL) double-gate (DG) MOSFET-based biosensors with and without gate stack (GS) has been studied. Here, the dielectric modulation (DM) method is applied to detect biomolecules in the cavity. The sensitivity of n-type JL-DM-DG-MOSFET and n-type JL-DM-GSDG-MOSFET-based biosensors have also been evaluated. The sensitivity (ΔVth) improved in JL-DM-GSDG MOSFET/JL-DM-DG-MOSFET-based biosensors for neutral/charged biomolecules is 116.66%/66.66% and 1165.78%/978.94%, respectively, compared with the previously reported results. The electrical detec
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Saha, Soumyadeep, Manoj Sachdev, and Sushanta K. Mitra. "Recent advances in label-free optical, electrochemical, and electronic biosensors for glioma biomarkers." Biomicrofluidics 17, no. 1 (2023): 011502. http://dx.doi.org/10.1063/5.0135525.

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Gliomas are the most commonly occurring primary brain tumor with poor prognosis and high mortality rate. Currently, the diagnostic and monitoring options for glioma mainly revolve around imaging techniques, which often provide limited information and require supervisory expertise. Liquid biopsy is a great alternative or complementary monitoring protocol that can be implemented along with other standard diagnosis protocols. However, standard detection schemes for sampling and monitoring biomarkers in different biological fluids lack the necessary sensitivity and ability for real-time analysis.
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11

Miller, Corwin A., Joanne M. L. Ho, and Matthew R. Bennett. "Strategies for Improving Small-Molecule Biosensors in Bacteria." Biosensors 12, no. 2 (2022): 64. http://dx.doi.org/10.3390/bios12020064.

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In recent years, small-molecule biosensors have become increasingly important in synthetic biology and biochemistry, with numerous new applications continuing to be developed throughout the field. For many biosensors, however, their utility is hindered by poor functionality. Here, we review the known types of mechanisms of biosensors within bacterial cells, and the types of approaches for optimizing different biosensor functional parameters. Discussed approaches for improving biosensor functionality include methods of directly engineering biosensor genes, considerations for choosing genetic re
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Srinivas, Burra. "Simulation Study of Dielectric Modulated Dual Material Gate TFET Based Biosensor." INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 09, no. 05 (2025): 1–9. https://doi.org/10.55041/ijsrem49228.

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ABSTRACT - This study focuses on the simulation and modeling of Tunnel Field-Effect Transistor (TFET) based biosensors for label-free detection of biomolecules. TFET biosensors offer high sensitivity and selectivity, making them promising for biomedical applications. Our simulation and modeling approach aims to optimize TFET biosensor design, improve detection accuracy, and reduce development time. We investigate the impact of various design parameters on biosensor performance and explore the potential of TFET biosensors for real-world applications. This research contributes to the development
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Vinay Kumar, Javalkar, Shylashree N, Seema Srinivas, Ajit Khosla, Hari Krishna R, and Manjunatha C. "Review on Biosensors: Fundamentals, Classifications, Characteristics, Simulations, and Potential Applications." ECS Transactions 107, no. 1 (2022): 13005–29. http://dx.doi.org/10.1149/10701.13005ecst.

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Biosensor is a device which combines a physical transducer and biological active elements. The biological active element recognizes the specific analyte and produces biorecognized signal, which is further converted into a measurable signal by using an appropriate physical transducer. This review paper attempts in providing a comprehensive survey of the topic biosensor and due to its selectivity and sensitivity, biosensors are mostly widely used than other diagnostic devices. Because of its important features like selectivity, sensitivity, stability, reproducibility, linearity, and low cost, bi
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Mohammadpour-Haratbar, Ali, Seyyed Behnam Abdollahi Boraei, Yasser Zare, Kyong Yop Rhee, and Soo-Jin Park. "Graphene-Based Electrochemical Biosensors for Breast Cancer Detection." Biosensors 13, no. 1 (2023): 80. http://dx.doi.org/10.3390/bios13010080.

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Breast cancer (BC) is the most common cancer in women, which is also the second most public cancer worldwide. When detected early, BC can be treated more easily and prevented from spreading beyond the breast. In recent years, various BC biosensor strategies have been studied, including optical, electrical, electrochemical, and mechanical biosensors. In particular, the high sensitivity and short detection time of electrochemical biosensors make them suitable for the recognition of BC biomarkers. Moreover, the sensitivity of the electrochemical biosensor can be increased by incorporating nanomat
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Alvarado-Ramírez, Lynette, Magdalena Rostro-Alanis, José Rodríguez-Rodríguez, et al. "Enzyme (Single and Multiple) and Nanozyme Biosensors: Recent Developments and Their Novel Applications in the Water-Food-Health Nexus." Biosensors 11, no. 11 (2021): 410. http://dx.doi.org/10.3390/bios11110410.

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The use of sensors in critical areas for human development such as water, food, and health has increased in recent decades. When the sensor uses biological recognition, it is known as a biosensor. Nowadays, the development of biosensors has been increased due to the need for reliable, fast, and sensitive techniques for the detection of multiple analytes. In recent years, with the advancement in nanotechnology within biocatalysis, enzyme-based biosensors have been emerging as reliable, sensitive, and selectively tools. A wide variety of enzyme biosensors has been developed by detecting multiple
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16

Insawang, Mekhala, Kongphope Chaarmart, and Tosawat Seetawan. "Development of Biosensors for Ethanol Gas Detection." Instrumentation Mesure Métrologie 21, no. 2 (2022): 49–57. http://dx.doi.org/10.18280/i2m.210203.

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This work developed a biosensor for the measurement of ethanol gas in the air. The biosensors were synthesized by mixing signal layer materials containing SiO2 and polyimide (PI) substrates using the enzyme Alcohol Dehydrogenase (ADH) and coenzyme Nicotinamide Adenine Dinucleotide (NAD+) as a biosensor. The electrodes were coated on biosensors by DC magnetron sputtering method for test the response performance of the developed biosensors. The ADH/NAD+ was immobilized on the Ag electrode by Glutaric dialaehyde 25 wt. % cross-linking procedure. It was found that, alcohol biosensors can be exhibi
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17

Karunakaran, Chandran, Murugesan Karthikeyan, Marimuthu Dhinesh Kumar, Ganesan Kaniraja, and Kalpana Bhargava. "Electrochemical Biosensors for Point of care Applications." Defence Science Journal 70, no. 5 (2020): 549–56. http://dx.doi.org/10.14429/dsj.70.16359.

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Biosensor refers to powerful and innovative analytical tool involving biological sensing element and transducer with broad range of applications, such as diagnosis, drug discovery, biomedicine, food safety and processing, environmental monitoring, security and defense. Recent advances in the field of biotechnology, microelectronics, and nanotechnology have improved the development of biosensors. Glucometers utilizing the electrochemical determination of oxygen or hydrogen peroxide employing immobilised glucose oxidase electrode seeded the discovery and development of biosensors. Molecular reco
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18

Kulkarni, Madhusudan B., Narasimha H. Ayachit, and Tejraj M. Aminabhavi. "Biosensors and Microfluidic Biosensors: From Fabrication to Application." Biosensors 12, no. 7 (2022): 543. http://dx.doi.org/10.3390/bios12070543.

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Biosensors are ubiquitous in a variety of disciplines, such as biochemical, electrochemical, agricultural, and biomedical areas. They can integrate various point-of-care applications, such as in the food, healthcare, environmental monitoring, water quality, forensics, drug development, and biological domains. Multiple strategies have been employed to develop and fabricate miniaturized biosensors, including design, optimization, characterization, and testing. In view of their interactions with high-affinity biomolecules, they find application in the sensitive detection of analytes, even in smal
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19

Leegsma‐Vogt, Gea, Maria M. Rhemrev‐Boom, Renger G. Tiessen, Kor Venema, and Jakob Korf. "The potential of biosensor technology in clinical monitoring and experimental research." Bio-Medical Materials and Engineering 14, no. 4 (2004): 455–64. https://doi.org/10.1177/095929892004014004012.

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Glucose or lactate biosensors are very useful for monitoring metabolism. Continuous monitoring of glucose is for example very important in diabetic patients. The measurement of lactate, a marker for oxygen deficiency, is used in the intensive care unit to monitor the patients' condition. In our laboratory we have developed two types of on‐line biosensors to measure in vivo glucose and lactate: a sandwich‐type biosensor and, very recently, a miniaturized flow‐through biosensor. These biosensors are not placed in the body itself, but are connected to implanted microdialysis or ultrafiltration pr
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20

Valencia, Germán Ayala, Luci Cristina de Oliveira Vercik, and Andrés Vercik. "A new conductometric biosensor based on horseradish peroxidase immobilized on chitosan and chitosan/gold nanoparticle films." Journal of Polymer Engineering 34, no. 7 (2014): 633–38. http://dx.doi.org/10.1515/polyeng-2014-0072.

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Abstract A new conductometric biosensor was developed and characterized; the biosensor was based on horseradish peroxidase that was deposited in chitosan and chitosan/AuNPs films. The biosensors were characterized by scanning electron microscopy and current-voltage curves. Current-voltage curves in biosensors showed that the electrical conductivity and bistability in biosensors can be modulated by horseradish peroxidase. Horseradish peroxidase catalyzed the reduction of H2 O2 to H2 O with the oxidation of the prosthetic group (Fe3+) in the enzyme to Fe4+=O. Conductometric signal in the biosens
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21

Xiao, Zhang. "Mainstream testing methods and non-enzyme electrochemical biosensors for glucose detection." Highlights in Science, Engineering and Technology 73 (November 29, 2023): 249–55. http://dx.doi.org/10.54097/hset.v73i.12982.

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Glucose is an indispensable substance in human’s body. A normal and stable blood glucose rate plays a significant role in leading a healthy living condition. Thus, an effective method to monitor glucose is what scientists are continuously studying to find. This work introduces the currently mainstream testing methods of glucose and a cutting-edge detecting equipment in this field. The mainstream methods include chromatography and biosensor methods. The biosensors are divided into two branches, optical and electrochemical biosensors. Colorimetric, fluorescence and chemiluminescence are three ma
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Kumar, Mohit, Khem B. Thapa, and Pawan Singh. "Long-range surface plasmon resonance biosensors with cytop/Al/Perovskite and cytop/Al/MoS2 configurations." Physica Scripta 97, no. 5 (2022): 055501. http://dx.doi.org/10.1088/1402-4896/ac5e5b.

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Abstract In this paper, long range surface plasmon resonance (LRSPR) biosensors with cytop/Al/Perovskite and cytop/Al/MoS2 configurations have been theoretically investigated and compared with standard LRSPR biosensor with cytop/Al/graphene configuration. To calculate the optical properties of considered configurations for the desired application, transfer matrix method for TM mode has been used to obtain reflectance. The sensitivity of the considered configurations for designed biosensors has been investigated with variation of optical parameters of the structure. A new configuration of LRSPR
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Sadaqat, Mohammad Hussain. "Types of biosensors and their application in the detection of microorganisms." Scientific-Research Quarterly Journal of Medical Science 9, no. 18 (2025): 32–44. https://doi.org/10.62134/kjms091832.

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Biosensors are devices for measuring the amount of analyte and chemical and biological reactions, which consist of a biological receptor, a transducer, an electronic part, and a display (depending on the type of biosensor). Various biosensors have been designed, the most important of which are optical biosensors, electrochemical and electronic biosensors, and mass-sensitive biosensors. Optical biosensors operate based on changes in the intensity, refraction, and reflection of light incident on a surface containing a bioreceptor and analyte (such as a microorganism), as seen in surface plasmon
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Gao, Aidai. "Advances in biosensors for poison detection applications." E3S Web of Conferences 553 (2024): 05002. http://dx.doi.org/10.1051/e3sconf/202455305002.

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This paper discusses the applications and challenges of biosensors in drug and toxin detection, highlighting the practical value of biosensors and their role in forensic investigations, medical research, and environmental monitoring. Because drug abuse poses a major threat to human health and society, there is an urgent need for technologies that can quickly, portable, and sensitively detect drugs in common biological samples. This paper introduces the detection of animal and plant toxins, including snake venom, spider toxins, cyanide in plants, etc., and discusses the importance of detection
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Wang, Xingya, and Guangchang Pang. "Amplification systems of weak interaction biosensors: applications and prospects." Sensor Review 35, no. 1 (2015): 30–42. http://dx.doi.org/10.1108/sr-03-2014-629.

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Purpose – This paper aims to provide a detailed review of weak interaction biosensors and several common biosensor methods for magnifying signals, as well as judiciously guide readers through selecting an appropriate detecting system and signal amplification method according to their research and application purpose. Design/methodology/approach – This paper classifies the weak interactions between biomolecules, summarizes the common signal amplification methods used in biosensor design and compares the performance of different kinds of biosensors. It highlights a potential electrochemical sign
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Abena, Tariku. "Biosensors Technological Advancement and their Biomedical, Agricultural, Environmental and Food Industrial Applications: A Review." Nanomedicine & Nanotechnology Open Access 8, no. 3 (2023): 1–15. http://dx.doi.org/10.23880/nnoa-16000262.

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The biosensors are devices that receive the biological message and convert it into a sensible electrical signal. The biosensing involves a combination of biological entities like DNA, RNA, and proteins/enzymes to the electrochemical transducers. Biosensors comprise biorecognition elements including enzymes, antigens, antibodies or nucleic acids that mediate selective biocatalysis or specific binding of analyte and transducers that able to measure the signal. There are several types of biosensors being employed today, such as optical, surface plasmon resonance, enzymes, DNA, Phage, and microbia
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Abena, Tariku. "Biosensors Technological Advancement and their Biomedical, Agricultural, Environmental and Food Industrial Applications: A Review." Nanomedicine & Nanotechnology Open Access 8, no. 3 (2023): 1–15. http://dx.doi.org/10.23880/nnoa-16000263.

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The biosensors are devices that receive the biological message and convert it into a sensible electrical signal. The biosensing involves a combination of biological entities like DNA, RNA, and proteins/enzymes to the electrochemical transducers. Biosensors comprise biorecognition elements including enzymes, antigens, antibodies or nucleic acids that mediate selective biocatalysis or specific binding of analyte and transducers that able to measure the signal. There are several types of biosensors being employed today, such as optical, surface plasmon resonance, enzymes, DNA, Phage, and microbia
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Abena, Tariku. "Biosensors Technological Advancement and Their Biomedical, Agricultural, Environmental and Food Industrial Applications: A Review." International Journal on Food, Agriculture and Natural Resources 4, no. 3 (2023): 46–57. http://dx.doi.org/10.46676/ij-fanres.v4i3.160.

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The biosensors are devices that receive the biological message and convert it into a sensible electrical signal. The biosensing involves a combination of biological entities like DNA, RNA, and proteins/enzymes to the electrochemical transducers. Biosensors comprise a biorecognition element (enzyme, antigen, antibody or nucleic) that mediates selective biocatalysis or specific binding of analyte and transducers that able to measure the signal. There are several types of biosensors being employed today, such as optical, surface plasmon resonance, enzymes, DNA, Phage, and microbial biosensors. No
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29

Gómez-Gómez, Maribel, Ángela Ruiz-Tórtola, Daniel González-Lucas, María-José Bañuls, and Jaime García-Rupérez. "New Method for Online Regeneration of Silicon-Based Nanophotonic Biosensors." Proceedings 4, no. 1 (2018): 22. http://dx.doi.org/10.3390/ecsa-5-05741.

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The optimal development of biosensors is a costly and time-consuming task, since an enormous amount of experiments is required. Therefore, the possibility of reusing the biosensors is highly desirable. In this work, a protocol based on the use of formamide for the regeneration of nanophotonic biosensors used for oligonucleotides detection is presented. This protocol was carried out online using the microfluidic system used to drive the target samples to the nanophotonic biosensor, thus allowing the possibility of running several experiments in a row using the same biosensor.
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Kim, Donggyu, Sungjun Byun, Younggun Pu та ін. "Design of a Current Sensing System with TIA Gain of 160 dBΩ and Input-Referred Noise of 1.8 pArms for Biosensor". Sensors 23, № 6 (2023): 3019. http://dx.doi.org/10.3390/s23063019.

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This paper proposes a high-gain low-noise current signal detection system for biosensors. When the biomaterial is attached to the biosensor, the current flowing through the bias voltage is changed so that the biomaterial can be sensed. A resistive feedback transimpedance amplifier (TIA) is used for the biosensor requiring a bias voltage. Current changes in the biosensor can be checked by plotting the current value of the biosensor in real time on the self-made graphical user interface (GUI). Even if the bias voltage changes, the input voltage of the analog to digital converter (ADC) does not c
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Hong, Leegon, Younghye Ro, Atsushi Kimura, Woojae Choi, and Danil Kim. "The Detection of Physiological Changes Using a Triaxial Accelerometer and Temperature Sensor-Equipped Bolus-Type Biosensor in Calves." Animals 14, no. 19 (2024): 2815. http://dx.doi.org/10.3390/ani14192815.

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In this study, a newly developed small wireless bolus biosensor, equipped with a triaxial accelerometer and temperature sensors, was applied to assess physiological changes in calves. The biosensor was orally implanted in calves, and its retention rate and location in the forestomach were examined. Data transmitted at 10 min intervals were analyzed to determine the characteristics of the calves at 10 and 100 days of age. Additionally, the daily averages of the vector magnitude (DV), changes in V over time (DV1), and reticular temperature (DRT) were analyzed during the experimental period. The
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Theyagarajan, K., and Young-Joon Kim. "Recent Developments in the Design and Fabrication of Electrochemical Biosensors Using Functional Materials and Molecules." Biosensors 13, no. 4 (2023): 424. http://dx.doi.org/10.3390/bios13040424.

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Electrochemical biosensors are superior technologies that are used to detect or sense biologically and environmentally significant analytes in a laboratory environment, or even in the form of portable handheld or wearable electronics. Recently, imprinted and implantable biosensors are emerging as point-of-care devices, which monitor the target analytes in a continuous environment and alert the intended users to anomalies. The stability and performance of the developed biosensor depend on the nature and properties of the electrode material or the platform on which the biosensor is constructed.
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Li, Qinggang, Haojie Ren, Zhenjiang Liao, Shuchang Xia, and Xue Sun. "High Throughput Screening of Transcription Factor LysG for Constructing a Better Lysine Biosensor." Biosensors 14, no. 10 (2024): 455. http://dx.doi.org/10.3390/bios14100455.

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The biosensors based on transcription factors (TFs) are widely used in high throughput screening of metabolic overproducers. The unsatisfactory performances (narrow detection and dynamic ranges) of biosensors limit their practical application and need more improvement. In this study, using the TF LysG (sensing lysine) as an example, a biosensor optimization method was constructed by growth-coupled screening of TF random mutant libraries. The better the performance of the biosensor, the faster the strain grows under screening pressure. A LysGE15D, A54D, and I164V-based biosensors were obtained,
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Lang, Yiqian. "Application performance of silicon-based different biosensors." Highlights in Science, Engineering and Technology 99 (June 18, 2024): 189–93. http://dx.doi.org/10.54097/gpddvh19.

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Biosensor is the equipment for biomolecules detection and it has been widely applied in a diverse of different fields such as disease diagnosis and harmful substance detection. Introducing different types of functional materials into biosensor can give it unique characteristics such as high sensitivity and high selectivity. Silicon, carbon nanotubes, gold, graphene and platinum are all trending materials for designing biosensors. Silicon is a non-toxic material that is commonly used as an element for biosensors. Different types of silicon-based functional materials have also been developed, wh
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Do Thi Hong, Diep, Duong Le Phuoc, Hoai Nguyen Thi, Serra Pier Andrea, and Rocchitta Gaia. "THE ROLE OF POLYETHYLENIMINE IN ENHANCING PERFORMANCE OF GLUTAMATE BIOSENSORS." Volume 8 Issue 3 8, no. 3 (2018): 36–41. http://dx.doi.org/10.34071/jmp.2018.3.6.

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Background: The first biosensor was constructed more than fifty years ago. It was composed of the biorecognition element and transducer. The first-generation enzyme biosensors play important role in monitoring neurotransmitter and determine small quantities of substances in complex matrices of the samples Glutamate is important biochemicals involved in energetic metabolism and neurotransmission. Therefore, biosensors requires the development a new approach exhibiting high sensibility, good reproducibility and longterm stability. The first-generation enzyme biosensors play important role in mon
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Ukirade, Neeta, and Priti Kolhe. "RECENT ADVANCEMENT IN ELECTROCHEMICAL BIOSENSOR BASED ON REDOX ENZYME COMPOSITE MODIFIED ELECTRODE FOR THE DETECTION OF BIOMOLECULES." Suranaree Journal of Science and Technology 31, no. 4 (2024): 030215(1–13). http://dx.doi.org/10.55766/sujst-2024-04-e04439.

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Recent developments in electrochemical biosensors have resulted in new applications in a variety of disciplines, such as clinical diagnosis, food processing quality control, and environmental monitoring. The electrochemical biosensor is a widely used sensing device that transmits an electrical signal from biological activities. Electrochemical biosensors have led to significant advancements in detecting various biomolecules such as uric acid, glucose, cholesterol, lactate, and DNA, including cancer biomarkers, viruses, and antibodies. An electrode is a vital part of this kind of sensor since i
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Baronas, Romas, and Karolis Petrauskas. "Sudėtinės geometrinės struktūros biojutiklių kompiuterinis modeliavimas." Informacijos mokslai 56 (January 1, 2011): 156–62. http://dx.doi.org/10.15388/im.2011.0.3141.

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Biojutikliai yra analitiniai įrenginiai, skirti medžiagų koncentracijoms matuoti. Kuriant naujus biojutiklius reikia atlikti daug eksperimentų. Siekiant sumažinti atliekamų fizinių eksperimentų skaičių taikomas kompiuterinis biojutiklių veiksmo odeliavimas, kai įprastai kiekvienam struktūriškai naujam biojutikliui yra sudaromas matematinis modelis, tuomet jis keičiamas skirtuminiu, o jo lygčių sistemos sprendimas įgyvendinamas sudarant kompiuterinį modelį. Kiekvienas žingsnis reikalauja atidos ir turėtų būti automatizuotas. Straipsnyje yra pateikiamas biojutiklio metamodelis, leidžiantis formu
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Раk, James Jungho, Min Ja Kim, Nam Ki Min, Chang-Woo Lee, and Soo Won Kim. "Application of Hydrothermally Grown ZnO Nanorods for Electrochemical Biosensors." Electronics and Communications 16, no. 2 (2011): 18–22. http://dx.doi.org/10.20535/2312-1807.2011.16.2.268091.

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ZnO nanorods have been used on Au working electrodes of biosensors for enhancing biosensor characteristics. ZnO nanorods grown on working electrodes have been employed for fabricating not only glucose sensors but also electrochemical immunosensors for detecting Legionella pneumophilia. The sensitivity of these biosensors was enhanced substantially compared to typical electrochemical biosensors based on Au working electrode
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Lee, Jinyoung. "Carbon Nanotube-Based Biosensors Using Fusion Technologies with Biologicals & Chemicals for Food Assessment." Biosensors 13, no. 2 (2023): 183. http://dx.doi.org/10.3390/bios13020183.

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High-sensitivity sensors applied in various diagnostic systems are considered to be a promising technology in the era of the fourth industrial revolution. Biosensors that can quickly detect the presence and concentration of specific biomaterials are receiving research attention owing to the breakthroughs in detection technology. In particular, the latest technologies involving the miniaturization of biosensors using nanomaterials, such as nanowires, carbon nanotubes, and nanometals, have been widely studied. Nano-sized biosensors applied in food assessment and in in vivo measurements have the
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Gilani Mohamed, Mohamed Ahmed, Ashok Vajravelu, and Nurmiza Binti Othman. "Biosensors Preliminary Concepts and Its Principles with Applications in the Engineering Perspective." International Journal of Science and Healthcare Research 6, no. 2 (2021): 77–81. http://dx.doi.org/10.52403/ijshr.20210415.

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Biosensor is rapid detection of any infectious disease at the early stages is critical for supporting public health and ensuring effective healthcare outcomes. A timely and accurate diagnosis of a disease is necessary for an effective medical response where is biosensor takes place. The design and development of biosensors have taken a centre stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications, such as health care and disease diagnosis, environmental monitoring, water and food quality monitoring, and drug delivery and lately it shown great
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Kidanemariam, Alemayehu, and Sungbo Cho. "Recent Advances in the Application of Metal–Organic Frameworks and Coordination Polymers in Electrochemical Biosensors." Chemosensors 12, no. 7 (2024): 135. http://dx.doi.org/10.3390/chemosensors12070135.

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Electrochemical biosensors are critical in advancing biomedical and pharmaceutical therapies because of their adaptability and cost-effectiveness. Voltammetric and amperometric sensors are of particular interest. These sensors typically consist of a specialized tip or biorecognition element and a transducer that converts biological data into readable signals. Efficient biosensor materials are essential for addressing health emergencies, with coordination polymers (CPs) and metal–organic frameworks (MOFs) showing promise. Functionalization strategies are necessary to enhance the usability of pr
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Yang, Chencan. "Application of the biosensors in autoimmune diseases." E3S Web of Conferences 553 (2024): 05019. http://dx.doi.org/10.1051/e3sconf/202455305019.

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Autoimmune diseases (AIDs) are chronic and multifactorial conditions resulting from the interaction between genetics, epigenetics, and environmental factors. The variety of these illnesses’ forms and presentations makes early detection of them difficult. To enable prompt intervention, biosensors have demonstrated efficacy in identifying biomarkers that signify the early stages of a disease. Biosensors have been developed since the first oxygen biosensor was invented in 1956, including wearable biosensors, which can monitor physiological parameters to detect autoimmune diseases early. Early det
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Ushaa, Eswaran, Eswaran Vivek, Murali Keerthna, and Eswaran Vishal. "Flexing frontiers: Pioneering advances in biosensors for instant health insights." i-manager’s Journal on Electronics Engineering 14, no. 1 (2023): 45. http://dx.doi.org/10.26634/jele.14.1.20191.

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Biosensors that incorporate a biological recognition element with a transducer offer a rapid, simple approach for selective detection of analytes. However, conventional rigid biosensors have limited capabilities for continuous on-body monitoring applications. The emergence of flexible electronics has opened new possibilities for developing conformal biosensing platforms that can intimately interface with soft, curvilinear surfaces like skin for non-invasive health tracking. This review covers the fundamentals of biosensor technologies and recent progress in flexible biosensors aimed at pointof
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Zhang, Huijia. "Advances and application of common biosensors." Theoretical and Natural Science 22, no. 1 (2023): 70–75. http://dx.doi.org/10.54254/2753-8818/22/20230940.

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Biosensors are devices that can detect and measure chemical components in organisms through specialized biological properties or reactions. This paper provides an overview of the three main types of biosensors: enzymatic, immunosensors, and microbial sensors. Enzymatic biosensors utilize enzymes to catalyze specific reactions between target molecules and other components of the biosensor, creating measurable signals. Immunosensors rely on immunological reactions between antigens and antibodies to detect and quantify substances in a solution. Microbial sensors use microbial cells to produce sig
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Soldatkin, O. O., O. V. Soldatkina, V. M. Arkhypova, et al. "APLLICATION OF GOLD NANOPARTICLES FOR IMPROVEMENT OF ANALYTICAL CHARACTERISTICS OF CONDUCTOMETRIC ENZYME BIOSENSORS." Sensor Electronics and Microsystem Technologies 18, no. 1 (2021): 20–34. http://dx.doi.org/10.18524/1815-7459.2021.1.227408.

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In this work, the possibility of application of gold nanoparticles for modification of bioselective elements of conductometric biosensors to improve their analytical characteristics has been tested. A bioselective elements of biosensors based on acetylcholinesterase, butyrylcholinesterase and glucose oxidase have been studied as a model of such system. Immobilization of enzymes on the surface of conductometric transducers was carried out by covalent crosslinking of enzymes by using a crosslinking agent (glutaraldehyde). The conditions for immobilization of acetylcholinesterase with gold nanopa
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Patil, Shikha, Shariq Suleman, Nigar Anzar, et al. "Origami-Inspired Biosensors: Exploring Diverse Applications and Techniques for Shape-Changing Sensor Platforms." Chemosensors 12, no. 12 (2024): 276. https://doi.org/10.3390/chemosensors12120276.

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Biosensors are widely used across industries such as healthcare, food safety, and environmental monitoring, offering high stability and sensitivity compared to conventional methods. Recently, origami—the art of folding 2D structures into 3D forms—has emerged as a valuable approach in biosensor development, enabling the creation of shape-changing devices. These origami-based biosensors are particularly useful in precision medicine, rapid diagnostics, and resource-limited settings, offering affordable, highly precise, and portable solutions with diverse applications. Paper and biological substra
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Kelly, Tynan, and Xiaolong Yang. "Application of Fluorescence- and Bioluminescence-Based Biosensors in Cancer Drug Discovery." Biosensors 14, no. 12 (2024): 570. http://dx.doi.org/10.3390/bios14120570.

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Recent advances in drug discovery have established biosensors as indispensable tools, particularly valued for their precision, sensitivity, and real-time monitoring capabilities. The review begins with a brief overview of cancer drug discovery, underscoring the pivotal role of biosensors in advancing cancer research. Various types of biosensors employed in cancer drug discovery are then explored, with particular emphasis on fluorescence- and bioluminescence-based technologies such as FRET, TR-FRET, BRET, NanoBRET, and NanoBiT. These biosensors have enabled breakthrough discoveries, including t
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Mohamad Nor, Noorhashimah, Nur Syafinaz Ridhuan, and Khairunisak Abdul Razak. "Progress of Enzymatic and Non-Enzymatic Electrochemical Glucose Biosensor Based on Nanomaterial-Modified Electrode." Biosensors 12, no. 12 (2022): 1136. http://dx.doi.org/10.3390/bios12121136.

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This review covers the progress of nanomaterial-modified electrodes for enzymatic and non-enzymatic glucose biosensors. Fundamental insights into glucose biosensor components and the crucial factors controlling the electrochemical performance of glucose biosensors are discussed in detail. The metal, metal oxide, and hybrid/composite nanomaterial fabrication strategies for the modification of electrodes, mechanism of detection, and significance of the nanomaterials toward the electrochemical performance of enzymatic and non-enzymatic glucose biosensors are compared and comprehensively reviewed.
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Valdés-Ramírez, Gabriela, Francisco Hernández-Ramírez, and Laura Galicia. "Contribution to the Electrochemical Sensors and Biosensors field by the Electrochemical and Analytical Chemistry research areas at UAM-I." Journal of the Mexican Chemical Society 69, no. 1 (2025): 156–72. https://doi.org/10.29356/jmcs.v69i1.2300.

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An overview of the electrochemical sensors and biosensors developed at Universidad Autónoma Metropolitana Unidad Iztapalapa, is summarized by describing the principal contributions in the field performed by the Electrochemistry and Analytical Chemistry research areas of the Chemistry Department. Here, we divided the contributions into four main groups: fabrication and characterization of surfaces, electrochemical sensors and biosensors with environmental applications, electrochemical sensors and biosensors with applications in the food industry, and electrochemical sensors and biosensors with
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Cristea, Cecilia. "Special Issue “Women in Science”—The First Edition." Biosensors 13, no. 4 (2023): 438. http://dx.doi.org/10.3390/bios13040438.

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This Special Issue entitled “Women in Biosensors” has been launched to celebrate and highlight the achievements of women in the biosensors research area, presenting biosensor-related work performed in groups leaded by women scientists [...]
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