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Relevant bibliographies by topics / Biosynthesis of rat adrenaline

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Academic literature on the topic 'Biosynthesis of rat adrenaline'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Biosynthesis of rat adrenaline"

1

Peltsch, Heather, Sandhya Khurana, Collin J. Byrne, et al. "Cardiac phenylethanolamine N-methyltransferase: localization and regulation of gene expression in the spontaneously hypertensive rat." Canadian Journal of Physiology and Pharmacology 94, no. 4 (2016): 363–72. http://dx.doi.org/10.1139/cjpp-2015-0303.

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Phenylethanolamine N-methyltransferase (PNMT) is the terminal enzyme in the catecholamine biosynthetic pathway responsible for adrenaline biosynthesis. Adrenaline is involved in the sympathetic control of blood pressure; it augments cardiac function by increasing stroke volume and cardiac output. Genetic mapping studies have linked the PNMT gene to hypertension. This study examined the expression of cardiac PNMT and changes in its transcriptional regulators in the spontaneously hypertensive (SHR) and wild type Wistar-Kyoto (WKY) rats. SHR exhibit elevated levels of corticosterone, and lower le

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Simonyi, Agnes, Bela Kanyicska, Tibor Szentendrei, and Marton I. K. Fekete. "Effect of chronic morphine treatment on the adrenaline biosynthesis in adrenals and brain regions of the rat." Biochemical Pharmacology 37, no. 4 (1988): 749–52. http://dx.doi.org/10.1016/0006-2952(88)90150-5.

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Shimbhu, Dawan, Kohichi Kojima, and Toshiharu Nagatsu. "A SENSITIVE ASSAY FOR NON-SPECIFIC N-METHYLTRANSFERASE ACTIVITY IN RAT TISSUES BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY ELECTROCHEMICAL DETECTION." ASEAN Journal on Science and Technology for Development 19, no. 1 (2017): 63–68. http://dx.doi.org/10.29037/ajstd.318.

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Phenylethanolamine N-methyltransferase (PNMT) and non-specific N -methyltransferase (EC 2.1.1.28) catalyze the N-methylation of aromatic amines. PNMT is specific for phenylethanolamines such as noradrenaline (NA). and catalyzes the step in catecholamine biosynthesis, forming adrenaline (AD) from NA. PNMT activity is high in adrenal gland, whereas non-specific N-methyltransferase is distributed in various tissues such as the lungs. Borchardt et al. first reported a method to detect PNMT activity by high-performance liquid chromatography electrochemical detection (HPLC-EICD), which could demonst

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4

Shimojo, M., C. B. Whorwood та P. M. Stewart. "11β-Hydroxysteroid dehydrogenase in the rat adrenal". Journal of Molecular Endocrinology 17, № 2 (1996): 121–30. http://dx.doi.org/10.1677/jme.0.0170121.

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ABSTRACT 11β-Hydroxysteroid dehydrogenase (11β-HSD) catalyses the interconversion of biologically active cortisol to inactive cortisone in man, and corticosterone to 11-dehydrocorticosterone in rodents. As such, this enzyme has been shown to confer aldosterone-selectivity on the mineralocorticoid receptor and to modulate cortisol/corticosterone access to the glucocorticoid receptor (GR). Two kinetically distinct isoforms of this enzyme have been characterized in both rodents and man; a low-affinity NADP(H)-dependent enzyme (11β-HSD1) which predominantly acts as an oxo-reductase and, more recen

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Deng, Xinqi, Nan Jiang, Li Guo, et al. "Protective Effects and Metabolic Regulatory Mechanisms of Shenyan Fangshuai Recipe on Chronic Kidney Disease in Rats." Evidence-Based Complementary and Alternative Medicine 2020 (August 25, 2020): 1–13. http://dx.doi.org/10.1155/2020/5603243.

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Background. Chronic kidney disease (CKD) is one of the major causes of renal damage. Shenyan Fangshuai Recipe (SFR), a modified prescription of traditional medicine in China, showed potent effects in alleviating edema, proteinuria, and hematuria of CKD in clinical practices. In this study, we aimed to investigate scientific evidence-based efficacy as well as metabolic regulations of SFR in CKD treatment. Materials and Methods. The effect of SFR on CKD was observed in a rat model which is established with oral administration of adenine-ethambutol mixture for 21 days. Further, metabolites in ser

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Galan, Xavier, Julia Peinado-Onsurbe, Monique Q. Robert, Maria Soley, Miquel Llobera, and Ignasi Ramírez. "Acute regulation of hepatic lipase secretion by rat hepatocytes." Biochemistry and Cell Biology 80, no. 4 (2002): 467–74. http://dx.doi.org/10.1139/o02-136.

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Hepatic lipase is involved in cholesterol uptake by the liver. Although it is known that catecholamines are responsible for the daily variation of enzyme activity, the mechanisms involved are poorly understood. Rat hepatocytes incubated with adrenaline or other Ca2+-mobilizing hormones were used as an experimental model. Adrenaline reduced in a similar proportion the secretion of both hepatic lipase and albumin. The effect of adrenaline disappeared completely in cells exposed to cycloheximide. Adrenaline decreased incorporation of [35S]Met into cellular and secreted proteins, but it affected n

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7

Khurana, Sandhya, Sujeenthar Tharmalingam, Alyssa Murray, and T. C. Tai. "Epigenetic regulation of phenylethanolamine N‐methyltransferase: implications for adrenaline biosynthesis." FASEB Journal 34, S1 (2020): 1. http://dx.doi.org/10.1096/fasebj.2020.34.s1.04160.

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8

Costa, Vera M., Luísa M. Ferreira, Paula S. Branco, et al. "Characterization of adrenaline and adrenaline-GSH adduct transport in freshly isolated rat cardiomyocytes." Toxicology Letters 180 (October 2008): S99. http://dx.doi.org/10.1016/j.toxlet.2008.06.405.

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9

Napolitano, Gaetana, Daniela Barone, Sergio Di Meo, and Paola Venditti. "Adrenaline induces mitochondrial biogenesis in rat liver." Journal of Bioenergetics and Biomembranes 50, no. 1 (2017): 11–19. http://dx.doi.org/10.1007/s10863-017-9736-6.

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Nahar, Nurun, and Nargis Akhter. "Effect of carvedilol on adrenaline-induced changes in serum electrolytes in rat." Bangladesh Medical Research Council Bulletin 35, no. 3 (2010): 105–9. http://dx.doi.org/10.3329/bmrcb.v35i3.4116.

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Circulating catecholamine that is increased in early phase of myocardial infarction alters serum electrolyte levels which might predispose to serious ventricular arrhythmias. In this study the effect of pretreatment of carvedilol on adrenaline-induced changes in the serum electrolytes (Mg2+, K+, Ca2+, Na+) was evaluated in rats. Adrenaline was administered at a dose of 2 mg/kg body weight subcutaneously 2 injections 24 hours apart and serum electrolytes were estimated at 12 hours, 24 hours and 7 days after the 2nd injection of adrenaline. Adrenaline administration initially caused hypomagnesem

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Dissertations / Theses on the topic "Biosynthesis of rat adrenaline"

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Tomlinson, A. "A morphometric and biochemical analysis of the adrenal medulla of the neonatal, adult and aged Wistar rat." Thesis, University of Nottingham, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384349.

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Makkar, H. P. S. "Glycine biosynthesis in rat and sheep muscle." Thesis, University of Nottingham, 1985. http://eprints.nottingham.ac.uk/13111/.

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Glycine is the third most abundant of the amino acids released by muscle. Perfused rat hind-limb and sheep diaphragm preparations were employed to study the origin of glycine produced by non-ruminant and ruminant muscle. Neither the degradation of muscle and erythrocyte glutathione nor the 'leaching out' of the intracellular glycine pool contributed to the glycine released by either muscle. When the perfusions were carried out with the medium free of amino acids, the proteolysis accounted for 57% of the total glycine release by the rat hind-limb and 38% by the sheep diaphragm. Minimum de novo

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Howe, T. "Biosynthesis of serum glycoproteins by isolated rat hepatocytes." Thesis, Bucks New University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371224.

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Yao, Zemin. "Phosphatidylcholine biosynthesis and lipoprotein secretion in rat hepatocytes." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/29220.

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Young male rats fed a choline-deficient diet for three days accumulated triacylglycerol (TG) in the liver, and had reduced very low density lipoprotein (VLDL), but not high density lipoprotein (HDL), levels in the plasma. Cultured hepatocytes obtained from these rats were used as a model system to investigate how choline deficiency affected hepatic lipogenesis, apolipoprotein synthesis and lipoprotein secretion. When the cells were cultured in a medium free of choline and methionine, the secretion of TG and phosphatidylcholine (PC) was impaired. Supplementation of choline, methionine or lysoph

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Ordway, Gregory Allen. "The effects of age on muscarinic and alpha adrenergic receptor systems of the rat urinary bladder /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu148725958026307.

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Galadari, Sehamuddin H. I. "Leukotriene biosynthesis and secondary messengers in rat basophilic leukaemia cells." Thesis, Imperial College London, 1991. http://hdl.handle.net/10044/1/46776.

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McLaughlin, Daniel Peter. "Pharmacological characterisation of the receptors for adrenaline and 5-hydroxytryptamine in the gastrointestinal tract of the rat and man." Thesis, Glasgow Caledonian University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293307.

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Murphey, Roberta Jean. "Synthesis of deoxyhypusine in eukaryotic initiation factor 4D in rat hepatoma cells." Diss., The University of Arizona, 1989. http://hdl.handle.net/10150/184691.

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The aim of this research was to study the mechanism involved in the synthesis of deoxyhypusine, the intermediate step in the synthesis of the amino acid hypusine. Oeoxyhypusine is derived from the butylamine moiety of a spermidine molecule which is added to the famino group of one lysine in the eukaryotic initiation factor 40 (eIF-4D). Initially, a hepatoma tissue cell (HTC) lysate with a pH of 9.5 in glycine buffer and with a depleted spermidine pool supported deoxyhypusine synthesis in protein. Since CHES buffer was as efficient as glycine buffer, the synthesis of deoxyhypusine was pH depend

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Yao, Zemin. "Isolation of rat liver CTP: phosphocholine cytidylyltransferase and regulation of hepatic phosphatidylcholine biosynthesis." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/25073.

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Two kinds of affinity chromatography, CDP-choline- and CTP-Sepharose 4B, were investigated for purification of the cytosolic CTP:phosphocholine cytidylyltransferase from rat liver. The enzyme did not show strong affinity for the CDP-choline Sepharose resin, but bound to the CTP-Sepharose column in the presence of 14 mM magnesium acetate. The combination of CTP affinity chromatography with ion-exchange techniques provided about 70-fold purification of the cytosolic enzyme with a specific activity of about 90 units per milligram protein. The influence of diphenylsulfone compounds on the synthe

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Liu, Jia. "Increased hexosamine biosynthesis and protein O-GLCNAC protect isolated rat heart from ischemia/reperfusion injury." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2006. http://www.mhsl.uab.edu/dt/2006p/liu.pdf.

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Books on the topic "Biosynthesis of rat adrenaline"

1

Chan, Tom Sze-Yin. The metabolic consequences of ascorbate biosynthesis in the rat. 2005.

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The effect of training on beta adrenergic receptor number in rat heart. 1986.

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3

Collard, Michael Wade. Biosynthesis and molecular cloning of sulfated glycoproteins 1 and 2 secreted by rat Sertoli cells. 1987.

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4

Diller, Philip Morgan. The role of cellular free cholestrol in the regulation of apolipoprotein E biosynthesis in FU5AH rat hepatoma. 1988.

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5

Yang, Lu Ying *. A comparative study of triacylglycerol biosynthesis via the monocylglyerol and phosphatidic acid pathways in rat small intestine. 1991.

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Book chapters on the topic "Biosynthesis of rat adrenaline"

1

Goodman, Richard H., Marc R. Montminy, Malcolm J. Low, and Joel F. Habener. "Biosynthesis of Rat Preprosomatostatin." In Advances in Experimental Medicine and Biology. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4615-7886-4_3.

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2

E. Olson, Robert, G. Hossein Dialameh, and Ronald Bentley. "The Biosynthesis of Coenzyme Q in the Rat." In Novartis Foundation Symposia. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470719213.ch14.

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3

Aoyagi, Kazumasa, Shoji Ohba, Mitsuhiro Miyazaki, et al. "Biosynthesis of Guanidinoacetic Acid in Isolated Rat Hepatocytes." In Guanidines. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4757-0752-6_8.

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4

Kubota, M., M. Nakane, T. Nakagomi, et al. "Sphingolipid Biosynthesis by L-PDMP After Rat MCA Occlusion." In Brain Edema XI. Springer Vienna, 2000. http://dx.doi.org/10.1007/978-3-7091-6346-7_70.

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Cighetti, Giuliana, Giovanni Galli, Rita Paroni, and Marzia Galli Kienle. "Effects of Inhibitors of Cholesterol Biosynthesis in Isolated Rat Hepatocytes." In Liver, Nutrition, and Bile Acids. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4615-9427-7_17.

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Cherian, M. G., D. M. Templeton, K. R. Gallant, and D. Banerjee. "Biosynthesis and Metabolism of Metallothionein in Rat during Perinatal Development." In Experientia Supplementum. Birkhäuser Basel, 1987. http://dx.doi.org/10.1007/978-3-0348-6784-9_50.

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Titos, Esther, Nan Chiang, Charles N. Serhan, et al. "Aspirin-Triggered 15-Epi-Lipoxin A4 Biosynthesis in Rat Liver Cells." In Advances in Experimental Medicine and Biology. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0193-0_31.

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Zevenbergen, J. L. "Relationship between Arachidonic Acid Biosynthesis and its Level in Rat Tissues." In Enzymes of Lipid Metabolism II. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5212-9_78.

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Oxenkrug, G., P. J. Requintina, K. White, and A. Yuwiler. "Chronopharmacological study of moclobemide effect on the rat pineal melatonin biosynthesis." In Amine Oxidases: Function and Dysfunction. Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-9324-2_44.

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Patel, Yogesh C., Hans H. Zingg, and C. B. Srikant. "Somatostatin-14 Like Immunoreactive forms in the Rat: Characterization, Distribution and Biosynthesis." In Advances in Experimental Medicine and Biology. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4615-7886-4_5.

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Conference papers on the topic "Biosynthesis of rat adrenaline"

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TAPPARELLI, C., P. GFELLER, S. SANJAR, and J. MORLEY. "COMPARISON BETWEEN IN VITRO AND IN VIVO AGGREGATION OF PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644539.

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The extensive utilisation of in vitro tests of platelet aggregation presumes that corresponding effects occur in vivo. Platelet aggregometry in vitro and in vivo have been compared using a range of agonists in order to test this assumption.PRP from citrated peripheral blood of man, rat and guinea-pig was exposed to ADP, adrenaline, serotonin, collagen, thrombin and PAF in a Born aggregometer to define the time course and amplitude of these responses. In rat and guinea-pig, these aggregatory stimuli have also been used to define the time course and amplitude of intrathoracic accumulation of 111

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2

Mendzheritckiy, A. M., A. N. Vovk, N. S. Isachkina, and D. S. Medvedev. "IMPACT OF CARDIOGEN INJECTION IN THE ADRENALINE-INDUCED STRESS MODEL ON THE RATE OF THE HEART INDEX AND WEIGHTED PARAMETERS OF RAT BODIES." In STATE AND DEVELOPMENT PROSPECTS OF AGRIBUSINESS Volume 2. DSTU-Print, 2020. http://dx.doi.org/10.23947/interagro.2020.2.35-37.

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The article presents the results of a study of the effect of Cardiogen on changes in heart rate and weight parameters of organs under stress in rats. The introduction of Cardiogen compensates for the stressful effect of adrenaline on the change in the relative mass of the heart, adrenal glands and spleen. Cardiogen also helps reduce heart rate to control values and manifestations of arrhythmia under stress.

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3

Gladwin, A. M., and J. Martin. "ARACHIDONIC ACID (AA) INDUCED AGGREGATION OF RAT PRO- MEGAKARYOBLASTS (RPM)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643542.

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Platelet aggregation can be induced in vitro by a variety of platelet agonists acting upon membrane receptors. Since platelets have only a limited ability to synthesise proteins, these receptors must be present in megakaryocytes. This was investigated using an eternal line line of RPMs. Cells were suspended in rat platelet free plasma (PFP) at a concentration of 105 cells ml-1 . 200μl aliquots of this were placed in a light aggregometer. For this suspension, and for an aliquot of PFP, light transmission was adjusted to zero and 100% respectively. Addition of ADP (plasma concentrations 1-100μM)

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Laekeman, G. M., A. Van Hoydonck, M. Van Diest, and A. G. Herman. "CHANGES IN PGE2 AND TXB2 FORMATION BY PLATELETS OF ATHEROSCLEROTIC RABBITS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644812.

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The synthesis of thromboxane B2 (TXB2) and prostaglandin E2 (PGE2) were studied in groups of 9 rabbits fed a normal diet or a diet containing 0.3 % of cholesterol. After 16 weeks, a platelet rich suspension containing 300.000 platelets/mm3 was prepared. Portions were incubated at 37°C with arachidonic acid (AA). Biosynthesis of PGE2, TXA2 and TXB2 was evaluated by the bioassay cascade system (rabbit coeliac and mesenteric artery and rat fundus strip) and by radioimmunoassay (RIA) :No significant differences were recorded for TXB2 after 1 or 10 minutes incubationA small portion of blood without

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Lumley, P., E. W. Collington, P. Hallett, et al. "THE EFFECTS OF GR32191, A NEW THROMBOXANE RECEPTOR BLOCKING DRUG,ON PLATELETS AND VASCULAR SMOOTH MUSCLE IN VITRO." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643754.

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The effect of a new thromboxane receptor blocking drug GR32191 ([1R-[1α(Z),2β,3β,5α]]-(+)-7-[5-[[(1,1"-biphenyl)-4-yl]methoxy] -3-hydroxy-2-(l-piperidinyl)cyclopentyl]-4-heptenoic acid,hydrochloride) has been examined upon platelets and vascular smooth muscle. In human platelet-rich plasma (PRP), aggregation to thromboxane(Tx) A2, PGH2, arachidonic acid, collagen andU-46619 was antagonised by GR32191 (IC50 range 2-36 nM).Primary aggregation (PRP treated with aspirin 10 pM) to ADP, 5-HT and adrenaline were unaffected by concentrations of GR32191 up to 10 pM. In human PRP, U-46619-induced aggreg

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De Clerck, F., R. Van de Wiele, B. Xhonneux, et al. "PLATELET TXA2 SYNTHETASE INHIBITION AND TXA2/PROSTAGLANDIN ENDOPEROXIDE RECEPTOR BLOCKADE COMBINED IN ONE MOLECULE (R 68070)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643465.

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F 68070, an oxime-alkane carboxylic acid derivative (Janssen Pharmaceutica), is a potent inhibitor of thromboxane A2 (TXA2) synthetase activity (IC50 in vitro against thrombin-stimulated human platelets in plasma : R 68070 : 2.9 x 10-8 M; CGS 13080 : 6 x 10-8 M; OKY-1581 : 8.2 x 10-8 M; dazmegrel : 2.6 x 10-8 M; dazoxiben : 2.3 x 10-8 M).The compound specifically inhibits platelet TXA2 synthetase activity (14C-arachidonic acid metabolism by washed human platelets) without effect on the cyclo-oxygenase, lipoxygenase (platelets, RBL cells) or prostacyclin synthetase activities (rat aortic rings)

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