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1

Layton, A. C., M. Muccini, M. M. Ghosh, and G. S. Sayler. "Construction of a Bioluminescent Reporter Strain To Detect Polychlorinated Biphenyls." Applied and Environmental Microbiology 64, no. 12 (1998): 5023–26. http://dx.doi.org/10.1128/aem.64.12.5023-5026.1998.

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ABSTRACT A bioluminescent reporter strain, Ralstonia eutrophaENV307(pUTK60), was constructed for the detection of polychlorinated biphenyls by inserting the biphenyl promoter upstream of the bioluminescence genes. In the presence of a nonionic surfactant, which enhances the solubility of chlorinated biphenyls, bioluminescence was induced three- to fourfold over background by biphenyl, monochlorinated biphenyls, and Aroclor 1242. The minimum detection limits for these compounds ranged from 0.15 mg/liter for 4-chlorobiphenyl to 1.5 mg/liter for Aroclor 1242.
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2

Gorbachev, Stanislav A., and yacheslav V. Zuev. "Synthesis and Mesomorphic Properties of Biphenyl Derivatives with Central Unit Based on 1,6-Hexamethylene Diisocyanate Oligomers." Liquid Crystals and their Application 22, no. 4 (2022): 27–36. http://dx.doi.org/10.18083/lcappl.2022.4.27.

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A number of compounds with biphenyl as a mesogenic fragment and a structure simulating LC dimers, polymers with mesogenic side chain groups and a star-shaped structure have been synthesized. An approach for the synthesis of such compounds under mild conditions and without a complex purification procedure with a quantitative yield, has been developed. The approach is the implementation of “click chemistry” methods for the synthesis of LC compounds. It has been shown that the LC state is observed only if there are three biphenyls in one molecule, i.e., the compounds appear to be similar to polye
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3

Chizzali, Cornelia, and Ludger Beerhues. "Phytoalexins of the Pyrinae: Biphenyls and dibenzofurans." Beilstein Journal of Organic Chemistry 8 (April 20, 2012): 613–20. http://dx.doi.org/10.3762/bjoc.8.68.

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Biphenyls and dibenzofurans are the phytoalexins of the Pyrinae, a subtribe of the plant family Rosaceae. The Pyrinae correspond to the long-recognized Maloideae. Economically valuable species of the Pyrinae are apples and pears. Biphenyls and dibenzofurans are formed de novo in response to infection by bacterial and fungal pathogens. The inducible defense compounds were also produced in cell suspension cultures after treatment with biotic and abiotic elicitors. The antimicrobial activity of the phytoalexins was demonstrated. To date, 10 biphenyls and 17 dibenzofurans were isolated from 14 of
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4

Şişman, T., F. Geyikoğlu, and M. Atamanalp. "Early life-stage toxicity in zebrafish (Danio rerio) following embryonal exposure to selected polychlorinated biphenyls." Toxicology and Industrial Health 23, no. 9 (2007): 529–36. http://dx.doi.org/10.1177/0748233708089042.

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Polychlorinated biphenyls are a widespread aquatic contaminant. In this article, specific polychlorinated biphenyl congeners were examined for embryo and early life-stage toxicity in zebrafish ( Danio rerio). A set of three polychlorinated biphenyl congeners (non-ortho polychlorinated biphenyl 126, mono-ortho polychlorinated biphenyl 28 and di-ortho polychlorinated biphenyl 153) were tested. The typical lesions observed were yolk sac edema, vertebra defect, craniofacial malformations (double head, triple retina), anaxial body and inhibition of swim bladder inflation. Moreover, embryo and larva
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5

Seeger, Michael, Beatriz Cámara, and Bernd Hofer. "Dehalogenation, Denitration, Dehydroxylation, and Angular Attack on Substituted Biphenyls and Related Compounds by a Biphenyl Dioxygenase." Journal of Bacteriology 183, no. 12 (2001): 3548–55. http://dx.doi.org/10.1128/jb.183.12.3548-3555.2001.

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ABSTRACT The attack by the bph-encoded biphenyl dioxygenase ofBurkholderia sp. strain LB400 on a number of symmetricalortho-substituted biphenyls or quasiortho-substituted biphenyl analogues has been investigated. 2,2′-Difluoro-, 2,2′-dibromo-, 2,2′-dinitro-, and 2,2′-dihydroxybiphenyl were accepted as substrates. Dioxygenation of all of these compounds showed a strong preference for the semisubstituted pair of vicinal ortho and metacarbons, leading to the formation of 2′-substituted 2,3-dihydroxybiphenyls by subsequent elimination of HX (X = F, Br, NO2, or OH). All of these products were furt
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6

Wang, Xing, Hao-Yu Fu, Wei He, et al. "Synthesis and Antibacterial Activity Evaluation of Biphenyl and Dibenzofuran Derivatives as Potential Antimicrobial Agents against Antibiotic-Resistant Bacteria." Current Issues in Molecular Biology 44, no. 9 (2022): 4087–99. http://dx.doi.org/10.3390/cimb44090280.

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The escalating prevalence of antibiotic-resistant bacteria has led to a serious global public health problem; therefore, there is an urgent need for the development of structurally innovative antibacterial agents. In our study, a series of biphenyl and dibenzofuran derivatives were designed and synthesized by Suzuki-coupling and demethylation reactions in moderate to excellent yields (51–94% yield). Eleven compounds exhibited potent antibacterial activities against the prevalent antibiotic-resistant Gram-positive and Gram-negative pathogens, among which compounds 4′-(trifluoromethyl)-[1,1′-bip
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7

Goldschmidt and P. Modderman. "Biphenyl derivatives II. Basic 4-Biphenyl compounds." Recueil des Travaux Chimiques des Pays-Bas 69, no. 9 (2010): 1109–17. http://dx.doi.org/10.1002/recl.19500690905.

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8

Maysoon T.Tawfiq. "Synthesis and characterization of some new heterocyclic compounds." Journal of the College of Basic Education 20, no. 86 (2023): 1031–48. http://dx.doi.org/10.35950/cbej.v20i86.9745.

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This work includes preparing of some new derivatives of pyrimidine ,pyrazolidine, and isoxazolidine from the reaction between tetraethyl 2,2' -(1E,1E' )- biphenyl ll-4, 4' -diylbis(diazene-1,2-diyl)dimalonate(1) and ammonia derivatives in dry ethanol to obtain the six membered hetero rings: 5,5'-(1E,1E') biphenyl-4,4'-diylbis (diazo-1,2-diyl)bis(2-mercaptopyrimidine-4,6-diol)(2) ; 5,5'-(1E,1E' ) biphenyl-4,4'-diylbis(diazo-1,2-diyl)dipyrimidine-2,4,6-triol(3);5,5'-(1E,1E')-biphenyl-4,4'-diylbis (diazo-1,2-diyl)bis(2-aminopyridine-4,6-diol)(4); and five membered hetero ring: 4,4' -(1E,1E')-biph
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9

Gesell, Manuela, Elke Hammer, Michael Specht, Wittko Francke, and Frieder Schauer. "Biotransformation of Biphenyl by Paecilomyces lilacinus and Characterization of Ring Cleavage Products." Applied and Environmental Microbiology 67, no. 4 (2001): 1551–57. http://dx.doi.org/10.1128/aem.67.4.1551-1557.2001.

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ABSTRACT We examined the pathway by which the fungicide biphenyl is metabolized in the imperfect fungus Paecilomyces lilacinus. The initial oxidation yielded the three monohydroxylated biphenyls. Further hydroxylation occurred on the first and the second aromatic ring systems, resulting in the formation of five di- and trihydroxylated metabolites. The fungus could cleave the aromatic structures, resulting in the transformation of biphenyl viaortho-substituted dihydroxybiphenyl to six-ring fission products. All compounds were characterized by gas chromatography-mass spectroscopy and proton nucl
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10

Parnell, J. Jacob, Joonhong Park, Vincent Denef, et al. "Coping with Polychlorinated Biphenyl (PCB) Toxicity: Physiological and Genome-Wide Responses of Burkholderia xenovorans LB400 to PCB-Mediated Stress." Applied and Environmental Microbiology 72, no. 10 (2006): 6607–14. http://dx.doi.org/10.1128/aem.01129-06.

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ABSTRACT The biodegradation of polychlorinated biphenyls (PCBs) relies on the ability of aerobic microorganisms such as Burkholderia xenovorans sp. LB400 to tolerate two potential modes of toxicity presented by PCB degradation: passive toxicity, as hydrophobic PCBs potentially disrupt membrane and protein function, and degradation-dependent toxicity from intermediates of incomplete degradation. We monitored the physiological characteristics and genome-wide expression patterns of LB400 in response to the presence of Aroclor 1242 (500 ppm) under low expression of the structural biphenyl pathway
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11

Rahmani Samani, Marzieh, Gilda D’Urso, Filomena Nazzaro, Florinda Fratianni, Milena Masullo, and Sonia Piacente. "Phytochemical Investigation and Biofilm-Inhibitory Activity of Bachtiari Savory (Satureja bachtiarica Bunge) Aerial Parts." Plants 13, no. 1 (2023): 67. http://dx.doi.org/10.3390/plants13010067.

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Satureja bachtiarica is an endemic plant from the Lamiaceae family, growing in the Zagros mountain range in Iran. Even if S. bachtiarica is reported to possess many biological activities, little is known about its chemical composition. For this reason, in the present research, a phytochemical investigation of this species was carried out. To have a preliminary metabolite profile of S. bachtiarica, the n-BuOH extract was analyzed using LC-ESI/LTQOrbitrap/MS/MS in negative ion mode, allowing the identification of specialized metabolites belonging to flavonoid, monoterpene, indol, phenylpropanoid
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12

Lehmler, Hans-Joachim, Larry W. Robertson, Sean Parkin, and Carolyn Pratt Brock. "Z′ = 4 structure without obvious pseudosymmetry: implications for the formation of solid-state compounds." Acta Crystallographica Section B Structural Science 58, no. 1 (2001): 140–47. http://dx.doi.org/10.1107/s0108768101018043.

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Crystals of 4-chloro-2′-biphenylol grown at 263 K and studied at both 293 and 142 K are loosely packed and contain OH...O bonded tetramers composed of four crystallographically independent molecules (Z′ = 4). Approximate symmetry relationships between independent molecules are apparent in many, perhaps even most, structures with Z′ > 1, but are not obvious in this structure. The inefficient crystal packing, the surprisingly large value of Z′ and the absence of pseudosymmetry reflect the difficulty of finding a dense molecular arrangement that also allows for hydrogen-bond formation. Impedim
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13

Khullar, Anju. "Studies and Synthesis of Substituted 4-Biphenyl Acetamide Derivatives." Asian Journal of Chemistry 31, no. 3 (2019): 510–14. http://dx.doi.org/10.14233/ajchem.2019.21579.

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A new series of substituted 4-biphenylamides have been synthesized by condensation of 4-biphenyl acetic acid with different primary amines (aromatic and aliphatic). 4-Biphenyl acetic acid was first treated with thionyl chloride in dry benzene to prepare substituted 4-biphenyl acetyl chloride, which is then treated with different aliphatic or aromatic amines to synthesize various substituted 4-biphenyl acid-amide derivatives. The structure of newly synthesized compounds has been established by analytical and spectral methods. These synthesized compounds have shown antifungal properties against
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14

Suenaga, Hikaru, Takahito Watanabe, Mika Sato, Ngadiman, and Kensuke Furukawa. "Alteration of Regiospecificity in Biphenyl Dioxygenase by Active-Site Engineering." Journal of Bacteriology 184, no. 13 (2002): 3682–88. http://dx.doi.org/10.1128/jb.184.13.3682-3688.2002.

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ABSTRACT Biphenyl dioxygenase (Bph Dox) is responsible for the initial dioxygenation step during the metabolism of biphenyl. The large subunit (BphA1) of Bph Dox plays a crucial role in the determination of the substrate specificity of biphenyl-related compounds, including polychlorinated biphenyls (PCBs). Based on crystallographic analyses of naphthalene dioxygenase (B. Kauppi, K. Lee, E. Carredano, R. E. Parales, D. T. Gibson, H. Eklund, and S. Ramaswamy, Structure 6:571-586, 1998), we developed a three-dimensional model of KF707 BphA1 of Pseudomonas pseudoalcaligenes KF707. Based on structu
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15

Patel, Pineshkumar N., and Denish C. Karia. "Synthesis and Antimicrobial Activity of Novel Series of Diversely Substituted Acetyl Pyrazoline Bearing Biphenyl Carbonitrile Motif." International Letters of Chemistry, Physics and Astronomy 69 (August 2016): 42–48. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.69.42.

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Novel series of diversely substituted acetyl pyrazoline having biphenyl carbonitrile motif have been synthesized. The reaction of 2-cyno-4’-bromomethyl biphenyl with1-(4-hydroxy-phenyl)-ethanone resulted in acetophenone derivative of biphenyl-2-carbonitrile. This acetophenone derivative was condensed with substituted aromatic aldehyde in mixed solvent resulted in various substituted chalcones. These chalcones were further cyclized using hydrazine hydrate in presence of glacial acetic acid to produce titled compound derivatives. The chemical structures of synthesized compounds were elucidated b
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16

Patel, Pineshkumar N., and Denish C. Karia. "Synthesis and Antimicrobial Activity of Novel Series of Diversely Substituted Acetyl Pyrazoline Bearing Biphenyl Carbonitrile Motif." International Letters of Chemistry, Physics and Astronomy 69 (August 12, 2016): 42–48. http://dx.doi.org/10.56431/p-al2z39.

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Novel series of diversely substituted acetyl pyrazoline having biphenyl carbonitrile motif have been synthesized. The reaction of 2-cyno-4’-bromomethyl biphenyl with1-(4-hydroxy-phenyl)-ethanone resulted in acetophenone derivative of biphenyl-2-carbonitrile. This acetophenone derivative was condensed with substituted aromatic aldehyde in mixed solvent resulted in various substituted chalcones. These chalcones were further cyclized using hydrazine hydrate in presence of glacial acetic acid to produce titled compound derivatives. The chemical structures of synthesized compounds were elucidated b
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17

Egorova, Darya O. "Polychlorinated biphenyls as a cause of ecological problems and development of remediation technologies based on biological agents." Anthropogenic Transformation of Nature 9, no. 2 (2023): 68–88. http://dx.doi.org/10.17072/2410-8553-2023-2-68-88.

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The review presents an analysis of currently pressing problems associated with environmental pollution by polychlorinated biphenyls – compounds included in the list of Persistent Organic Pollutants under the international con-vention. The structural features of the polychlorinated biphenyl molecule and their interaction with the environment and living organisms are shown. The main attention is paid to aerobic bacteria, one of the main components of soil microbi-ocenosis. It was shown that long-term exposure to polychlorinated biphenyls led to the preferential selection in contaminated microbio
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18

Ruffin, Brigitte, Stéphane Grelier, Aziz Nourmamode, and Alain Castellan. "Attempt to approach the role of phenolic phenylpropenol structures in the photoyellowing of softwood mechanical pulps." Canadian Journal of Chemistry 80, no. 9 (2002): 1223–31. http://dx.doi.org/10.1139/v02-123.

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Three biphenyl (I, II, III) compounds and a benzylarylether (IV) compound were synthesized to detect and quantify the presence of phenolic phenylpropenols in unbleached, peroxide-bleached, or sodium borohydride-reduced mechanical softwood pulps. The methodology used is based on a gas chromatography – mass spectrometry search of the prepared compounds in the residue obtained after ethylation, thioacidolysis, and desulfurization of the pulps. Detection of biphenyl I ([Formula: see text]4 × 10–6 mol g–1) in unbleached and NaBH4-reduced pulps is indicative of the presence of phenolic coniferaldehy
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19

Penon, Oriol, Filippo Marsico, Davide Santucci, Laura Rodríguez, David B. Amabilino, and Lluïsa Pérez-García. "Multiply biphenyl substituted zinc(II) porphyrin and phthalocyanine as components for molecular materials." Journal of Porphyrins and Phthalocyanines 16, no. 12 (2012): 1293–302. http://dx.doi.org/10.1142/s1088424612501453.

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The preparation and physico-chemical characteristics of zinc(II) porphyrin and phthalocyanine derivatives with biphenyl units are reported. These compounds have been prepared as components for molecular electronics systems and rotor-based molecular machines, where the biphenyl units can act as paddles because they are oriented quasi-perpendicularly to the plane of the aromatic macrocycles which would be coordianted through the transition metal ion by an axial ligand. The minimalist design along with the absence of solubilizing groups leads to a low solubility of the compounds in organic solven
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20

BOUQUETSOMRANI, C., A. FINIELS, P. GRAFFIN, and J. OLIVE. "Photocatalytic degradation of hydroxylated biphenyl compounds." Applied Catalysis B: Environmental 8, no. 1 (1996): 101–6. http://dx.doi.org/10.1016/0926-3373(95)00059-3.

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21

Subbiah Pandi, A., D. Velmurugan, V. Raghu Kumar, V. T. Ramakrishnan, S. Shanmuga Sundararaj, and H. K. Fun. "Crystal Structures of Two Biphenyl Compounds." Crystal Research and Technology 35, no. 11-12 (2000): 1373–81. http://dx.doi.org/10.1002/1521-4079(200011)35:11/12<1373::aid-crat1373>3.0.co;2-r.

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22

Spasov, Alexander A., Anastasia A. Brigadirova, Olga N. Zhukovskaya, Anatoly S. Morkovnik, and Yuliya V. Lifanova. "Search for compounds with antioxidant and antiradical activity among N9-substituted 2-(biphenyl-4-yl)imidazo[1,2-a]benzimidazoles." Research Results in Pharmacology 8, no. 3 (2022): 41–48. http://dx.doi.org/10.3897/rrpharmacology.8.85498.

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Introduction: Biphenyl and imidazobenzimidazole derivatives attract ongoing attention as a combination of these two privileged substructures with promising pharmacological activities. The aim of this study was to synthesize and investigate in vitro antioxidant activity of promising novel compounds: 2-(biphenyl-4-yl)imidazo[1,2-a]benzimidazoles. Materials and methods: The newly synthesized compounds were characterized by IR, 1H NMR and CHBr(Cl)NO analyses. All newly synthesized compounds were screened for their in vitro antioxidant activity: inhibition of lipid peroxidation (LPO), 2,2’-azino-bi
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23

Somani, R., P. Dubey, and S. Zine. "MICROWAVE ASSISTED SYNTHESIS OF BIPHENYL BASED SCHIFF’S BASES AND THEIR ANTIMICROBIAL EVALUATION." INDIAN DRUGS 55, no. 03 (2018): 13–18. http://dx.doi.org/10.53879/id.55.03.11218.

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Schiff’s base constitutes a significant class of compounds for new drug development. They are widely used for industrial purposes and also exhibit a broad range of biological activities. The search for Schiff’s base containing compounds with more selective activity and lower side effects continues to be an active area of argument examination in medicinal chemistry. The biphenyl molecule consists of two connected phenyl rings. Biphenyl ring scaffolds are fairly non-reactive in nature. They enhance the log-P values; increase the tropical polar surface area (TPSA) of the molecule, act as hydropho
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24

Pawar, P. Y., P. M. Gaikwad, and P. H. Balani. "Microwave Assisted Synthesis of N-Substituted-7-hydroxy-4-methyl-2-oxoquinolines as Anticonvulsant Agents." E-Journal of Chemistry 8, no. 2 (2011): 945–51. http://dx.doi.org/10.1155/2011/121476.

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The reaction of resorcinol with ethylacetoacetate yielded the 7-hydroxy-4-methyl coumarin (1), which on treatment with benzidine gives 1-(4ʹ-amino-biphenyl-4-yl)-7-hydroxy-4-methyl-1H-quinolin-2-one (2). 1-{4ʹ-[(Substituted benzylidene)-amino]-biphenyl-4-yl}-7-hydroxy-4-methyl-1H-quinolin-2-one (3a-j) were obtained by reacting 1-(4ʹ-amino-biphenyl-4-yl)-7-hydroxy-4-methyl-1H-quinolin-2-one (2) with different substituted aromatic aldehydes in presence of glacial acetic acid by microwave irradiation. The compound 1-{4ɴ-[(substituted benzylidene)-amino]-biphenyl-4-yl}-7-hydroxy-4-methyl-1H-quinol
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25

Orzeszko, Andrzej, Dorota Melon-Ksyta, Ewa Kowalczyk, and Krzysztof Czupryński. "Synthesis and Liquid Crystalline Properties of Novel Imides and Thioimides with Chiral Aliphatic Tails." Zeitschrift für Naturforschung B 58, no. 10 (2003): 1015–20. http://dx.doi.org/10.1515/znb-2003-1013.

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Three chiral compounds (R)-octan-2-ol, (S)-citronellol and (S)-citronellyl bromide were used for the synthesis of novel ester imides with biphenyl moieties as mesogenic units. Observations by means of polarising microscopy as well as DSC measurements revealed the presence of SmC* and/or SmA phases for all the compounds examined. It was found that the biphenyl units with long chiral alkoxy substituents induce smectic C phases.
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26

Mokhtar, Gofran Safi, and Nuha Hussain Al-Saadawy. "Synthesis, Characterization, and Theoretical Study of a New Organotellurium Ligands Containing Amino Group." Indonesian Journal of Chemistry 23, no. 1 (2022): 148. http://dx.doi.org/10.22146/ijc.75583.

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The aim of the current study is to prepare organomercury and organotellurium compounds containing amino groups such as [1,1'-biphenyl]-4-amine and their derivatives by a mercuriation reaction. The research includes the preparation of a new organotellurium compound based on [1,1'-biphenyl]-4-amine. C12H10NHgCl (A) was obtained by mercuriation reaction to [1,1'-biphenyl]-4-amine by mercuric acetate and lithium chloride. C12H10Br3NTe (B), C24H20N2Br2Te (C), C24H20N2Te (D), and C24H20N2Te2 (E) were prepared by different reactions to get the corresponding compounds. All the prepared ligands were ch
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27

Gałuszka, Agnieszka, Zdzisław M. Migaszewski, and Neil L. Rose. "A consideration of polychlorinated biphenyls as a chemostratigraphic marker of the Anthropocene." Anthropocene Review 7, no. 2 (2020): 138–58. http://dx.doi.org/10.1177/2053019620916488.

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Polychlorinated biphenyls, organic pollutants of anthropogenic origin, were widely used in many industrial applications worldwide roughly from the 1930s to the 1970s. Both the use and disposal of polychlorinated biphenyls contributed to their ubiquity in different environmental compartments, and they show extremely high persistence because of their high physical and chemical stability. Concentrations of polychlorinated biphenyls in environmental archives located in different parts of the world usually show an initial increase in the 1940s–1950s and maxima in the 1960s–1970s followed by a sharp
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28

Tan, Monica Bernard, Alexandre N. Sobolev, Colin L. Raston, Scott J. Dalgarno, and Irene Ling. "Interplay of Ionic Species in Salts of Homoleptic Quaternary Phosphonium Cations Bearing Linear Biphenyl Moieties." Crystals 13, no. 1 (2022): 59. http://dx.doi.org/10.3390/cryst13010059.

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Quaternary phosphonium salts are popular candidates used in many chemical transformations and synthetic chemistry, notably in catalysis. We have examined the single crystals of two bulky phosphonium compounds, tetra([1,1′-biphenyl]-4-yl) phosphonium dicyanamide (C48H36P+·N(CN)2−, compound 1), and tetra([1,1′-biphenyl]-4-yl) phosphonium bromide hydrate (C48H36P+·Br−, CH3CN, H2O, compound 2), and herein report the structural properties for the compounds with an emphasis on the influence of the ion-ion interaction towards self-assembly; the overall self-assembly for both structures is very simila
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29

Bagnich, Sergey A., Alexander Rudnick, Pamela Schroegel, Peter Strohriegl, and Anna Köhler. "Triplet energies and excimer formation in meta - and para -linked carbazolebiphenyl matrix materials." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 373, no. 2044 (2015): 20140446. http://dx.doi.org/10.1098/rsta.2014.0446.

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We present a spectroscopic investigation on the effect of changing the position where carbazole is attached to biphenyl in carbazolebiphenyl (CBP) on the triplet state energies and the propensity to excimer formation. For this, two CBP derivatives have been prepared with the carbazole moieties attached at the ( para ) 4- and 4 ′ -positions ( p CBP) and at the ( meta ) 3- and 3 ′ -positions ( m CBP) of the biphenyls. These compounds are compared to analogous m CDBP and p CDBP, i.e. two highly twisted carbazoledimethylbiphenyls, which have a high triplet energy at about 3.0 eV and tend to form t
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30

Sihag, Sheetal, Parvesh Devi, Rajvir Singh, and Sushila Singh. "Synthesis, Characterization and Bioactivity of Propranolol and it's Derivatives." Asian Journal of Organic & Medicinal Chemistry 7, no. 1 (2022): 92–98. http://dx.doi.org/10.14233/ajomc.2022.ajomc-p368.

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Herein, the conventional method used for β-blocker synthesis is initiated by refluxing biphenyl-2-ol (1) with an epoxy ring (2) in the presence of K2CO3 to obtain 2-[(biphenyl-2-yloxy)methyl]oxirane (3). Compound (3) was then reacted with 99% isopropylamine (4) and various substituted phenols (6a-i) to form 1-(biphenyl-2-yloxy)-3-(propan-2-ylamino)propan-2-ol (5) and 1-(2,6-dimethyl-/4-methoxy- /4-chloro-3-hydroxy-/2,6-dimethoxy-/3,4-dimethyl-/4-amine-/4-bromo/3,4-dinitro-/2,4- dihydroxyphenoxy)-3-(biphenyl-2-yloxy)-propan-2-ols (7a-i), respectively. The synthesized compounds were analyzed by
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31

Ginestra, Giovanna, Teresa Gervasi, Francesca Mancuso, et al. "Evaluation of the In Vitro Antifungal Activity of Novel Arylsulfonamides against Candida spp." Microorganisms 11, no. 6 (2023): 1522. http://dx.doi.org/10.3390/microorganisms11061522.

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The antifungal activity of molecules belonging to the arylsulfonamide chemotype has previously been demonstrated. Here, we screened arylsulfonamide-type compounds against a range of Candida spp. and further established the structure–activity relationship based on a “hit compound”. A series of four sulfonamide-based compounds, N-(4-sulfamoylbenzyl) biphenyl-4-carboxamide (3), 2,2-diphenyl-N-(4-sulfamoylbenzyl) acetamide (4), N-(4-sulfamoylphenethyl) biphenyl-4-carboxamide (5) and 2,2-diphenyl-N-(4-sulfamoylphenethyl) acetamide (6), were tested against the American Type Culture Collection (ATCC)
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32

Wan, Anqi, Narsimha Reddy Penthala, E. Kim Fifer, Sean Parkin, and Peter A. Crooks. "Comparison crystal structure conformations of two structurally related biphenyl analogues: 4,4′-bis[3-(pyrrolidin-1-yl)prop-1-yn-1-yl]-1,1′-biphenyl and 4,4′-bis{3-[(S)-2-methylpyrrolidin-1-yl]prop-1-yn-1-yl}-1,1′-biphenyl." Acta Crystallographica Section E Crystallographic Communications 71, no. 10 (2015): 1147–50. http://dx.doi.org/10.1107/s2056989015016163.

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The title compounds, C26H28N2, (I), and C28H32N2, (II), were designed based on the structure of the potent α9α10 nicotinic acetylcholine receptor antagonist ZZ161C {1,1′-[[1,1′-biphenyl]-4,4′-diylbis(prop-2-yne-3,1-diyl)]bis(3,4-dimethylpyridin-1-ium) bromide}. In order to improve the druglikeness properties of ZZ161C for potential oral administration, the title compounds (I) and (II) were prepared by coupling 4,4′-bis(3-bromoprop-1-yn-1-yl)-1,1′-biphenyl with pyrrolidine, (I), and (S)-2-methylpyrrolidine, (II), respectively, in acetonitrile at room temperature. The asymmetric unit of (I) cont
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33

Pedersen, Hans Albert, Stine Krogh Steffensen, Kirsten Heinrichson, and Inge S. Fomsgaard. "Biphenyl Columns Provide Good Separation of the Glucosides of DIMBOA and DIM2BOA." Natural Product Communications 12, no. 7 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200708.

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Hydroxamic acids are important defense compounds in cereals and have been subject to extensive research. Two important hydroxamic acids in maize are 2-β-D-glucopyranosyloxy-4-hydroxy-7-methoxy-2 H-1,4-benzoxazin-3(4 H)-one (DIMBOA-glc) and its 8-methoxylated derivative (DIM2BOA-glc). The compounds are typically reported as resolved by mass spectrometry rather than chromatography, with DIM2BOA-glc quantified relative to DIMBOA-glc. Biphenyl HPLC columns, however, allow good separation of the two compounds at both the analytical and semi-preparative scale, enabling both isolation and absolute qu
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34

Yadav, Neelam, and Ajar Nath Yadav. "Biodegradation of biphenyl compounds by soil microbiomes." Biodiversity International Journal 3, no. 2 (2019): 37–40. http://dx.doi.org/10.15406/bij.2019.03.00125.

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35

Llevot, A., E. Grau, S. Carlotti, S. Grelier, and H. Cramail. "ADMET polymerization of bio-based biphenyl compounds." Polymer Chemistry 6, no. 44 (2015): 7693–700. http://dx.doi.org/10.1039/c5py01232e.

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36

TAKASE, Ichiro, Toshio OMORI, and Yasuji MINODA. "Microbial degradation products from biphenyl-related compounds." Agricultural and Biological Chemistry 50, no. 3 (1986): 681–86. http://dx.doi.org/10.1271/bbb1961.50.681.

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37

Watanabe, Keisuke, Siti Muslimah Widyastuti, and Fukuji Nonaka. "Two Biphenyl Compounds fromRhaphiolepsis umbellataas Its Phytoalexin." Agricultural and Biological Chemistry 54, no. 7 (1990): 1861–62. http://dx.doi.org/10.1080/00021369.1990.10870194.

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38

Hohnholz, D., K. H. Schweikart, L. R. Subramanian, A. Wedel, W. Wischert, and M. Hanack. "Synthesis and studies on luminescent biphenyl compounds." Synthetic Metals 110, no. 2 (2000): 141–52. http://dx.doi.org/10.1016/s0379-6779(99)00291-x.

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39

Takase, Ichiro, Toshio Omori, and Yasuji Minoda. "Microbial Degradation Products from Biphenyl-related Compounds." Agricultural and Biological Chemistry 50, no. 3 (1986): 681–86. http://dx.doi.org/10.1080/00021369.1986.10867453.

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40

Shahin, Nabil, Nawaf Abu-Khalaf, Mazen Salman, and Harun Parlar. "Testing the Possibility of Photochemical Synthesis of Chlorinated Phenols, Benzenes and Biphenyl: Pre-study Guide for Standards Synthesis." مجلة جامعة فلسطين التقنية للأبحاث 4, no. 2 (2016): 73–83. http://dx.doi.org/10.53671/pturj.v4i2.47.

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Since deuterium 2H (D) is an isotope of hydrogen 1H, the testing of the possibility of photochemical synthesis of marked chlorinated phenol, biphenyl and benzene using normal solvents was studied. The irradiation of full chlorinated compounds dissolved in normal solvents such as MeOH or n-hexane has led to a reaction substitution in which a chlorine atom was substituted by hydrogen atom forming less grade chlorinated chlorophenols, biphenyls and benzenes. The quantum yields of pentachlorophenol, decachlorobiphenyl and hexachlorobenzene under irradiation using polychromatic light were calculate
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41

Shahin, Nabil, Nawaf Abu-Khalaf, Mazen Salman, and Harun Parlar. "Testing the Possibility of Photochemical Synthesis of Chlorinated Phenols, Benzenes and Biphenyl: Pre-study Guide for Standards Synthesis." مجلة جامعة فلسطين التقنية خضوري للأبحاث 4, no. 2 (2016): 73–83. http://dx.doi.org/10.53671/ptukrj.v4i2.47.

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Since deuterium 2H (D) is an isotope of hydrogen 1H, the testing of the possibility of photochemical synthesis of marked chlorinated phenol, biphenyl and benzene using normal solvents was studied. The irradiation of full chlorinated compounds dissolved in normal solvents such as MeOH or n-hexane has led to a reaction substitution in which a chlorine atom was substituted by hydrogen atom forming less grade chlorinated chlorophenols, biphenyls and benzenes. The quantum yields of pentachlorophenol, decachlorobiphenyl and hexachlorobenzene under irradiation using polychromatic light were calculate
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42

Ikpa, Chinyere B. C., Samuel O. Onoja, and Anastasia O. Okwaraji. "Synthesis And Antibacterial Activities Of Benzothiazole Derivatives Of Sulphonamides." Acta Chemica Malaysia 4, no. 2 (2020): 55–57. http://dx.doi.org/10.2478/acmy-2020-0009.

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AbstractThis study aims to synthesize hybrid compounds “via” the coupling of sulphonamide and benzothiazole into one structure that may have improved antibacterial property. The N-(biphenyl-4-yl) thiourea (1) used for the synthesis of the targeted sulphonamides was obtained by reacting diphenylamine and ammonium thiocyanate at room temperature. Cyclization of N-(biphenyl-4-yl)thiourea gave 2-amino-6-phenylbenzothiazole (2) which reacted with benzenesulphonyl chloride and para-toulene sulphonyl chloride to give the targeted sulphonamides (3a &amp; 3b). The synthesized compounds were characteris
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Kumar, Jat Rakesh, Jat Jawahar L., and D. P. Pathak. "Synthesis of Benzimidazole Derivatives: As Anti-hypertensive Agents." E-Journal of Chemistry 3, no. 4 (2006): 278–85. http://dx.doi.org/10.1155/2006/765712.

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A new series of non peptide angiotensin(A-II) receptor antagonist has been prepared. ThisN-(biphenyl methyl) imidazolese.g. 5-substituted (amino) -2- phenyl-1-(2ʼcarboxy biphenyl-4-yl) benzimidazoles differ from the previously reported and related compounds in that they produce a potent hypertensive effect upon oral administration. The earlier series were generally active only when administered intravenously. It has been found that 2’-position of biphenyl is essential. Only ortho substituted acid possess both high affinity for the AII receptor and oral anti-hypertensive potency.
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Wang, Chao-Nan, Yong-Heng Lu, Yue Liu, Jun Liu, Yao-Yue Yang, and Zhi-Gang Zhao. "Electrochemical coupling halobenzene into biphenyl on a reusable Pd nanoparticle-coated carbon-paper electrode at ambient conditions." New Journal of Chemistry 45, no. 8 (2021): 3997–4003. http://dx.doi.org/10.1039/d0nj06027e.

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45

Venkatesan, Naveen R., Ali Mahdi, Brian Barraza, Guang Wu, Michael L. Chabinyc, and Ram Seshadri. "Enhanced yield-mobility products in hybrid halide Ruddlesden–Popper compounds with aromatic ammonium spacers." Dalton Transactions 48, no. 37 (2019): 14019–26. http://dx.doi.org/10.1039/c9dt03074c.

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Two hybrid halide Ruddlesden–Popper compounds using the cation 2-(4-biphenyl)ethylammonium show higher yield-carrier mobility products by time-resolved microwave conductivity than compounds with n-butylammonium cations.
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46

Bickert, Peter, and Klaus Hafner. "Pentamethylcyclopentadienyl rhodium complexes of dihydro-s-indacenophanes: Transannular interactions." Collection of Czechoslovak Chemical Communications 53, no. 10 (1988): 2418–28. http://dx.doi.org/10.1135/cccc19882418.

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Transannular interactions in pentamethylcyclopentadienyl rhodium complexes (Me5C5Rh) of 18,22(18,20)-dihydro[2](4,4')biphenylo[2](2,6)-s-indacenophane (IV) and 12,16(12,18)-dihydro[2]pacacyclo[2](4,8)-s-indacenophane (IX) were investigated. The capability of a Me5C5Rh group to reduce electron density in both decks of these phanes was established. The deprotonation product VII of 18a,19,19a,22a,23,23a-η6-(18,22(18,20)-dihydro[2](4,4')biphenylo[2](2,6)-s-indacenophane-η5-(pentamethylcyclopentadienyl)rhodium(III) bis(hexafluoroantimonate) (V) was isolated as the first representative of a class of
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47

Vadra, Nahir, Sebastian A. Suarez, Leonardo D. Slep, et al. "Synthesis and crystallographic, spectroscopic and computational characterization of 3,3′,4,4′-substituted biphenyls: effects of OR substituents on the intra-ring torsion angle." Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials 76, no. 3 (2020): 366–77. http://dx.doi.org/10.1107/s2052520620004102.

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Presented here are the synthesis, characterization and study (using single crystal X-ray diffraction, Raman scattering, quantum mechanics calculations) of the structures of a series of biphenyls substituted in positions 3, 3′, 4 and 4′ with a variety of R (R = methyl, acetyl, hexyl) groups connected to the biphenyl core through oxygen atoms. The molecular conformation, particularly the torsion angle between aromatic rings has been extensively studied both in the solid as well as in the liquid state. The results show that the compounds appearing as rigorously planar in the solid present instead
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48

You, Dong Kyun, Seon Hee Lee, Ji Hye Lee, et al. "Synthesis and photophysical properties of phenanthroimidazole–triarylborane dyads: intriguing ‘turn-on’ sensing mediated by fluoride anions." RSC Advances 7, no. 17 (2017): 10345–52. http://dx.doi.org/10.1039/c6ra28559g.

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Phenanthroimidazole-based triarylborane compounds with an N-phenyl or N-biphenyl bridge were prepared and these compounds show ratiometrical ‘turn-on’ response in PL spectra upon fluoride binding to the borane moiety.
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49

Hossain, Mohammad Mamun, Sukanta Kumar Shaha, and Foysal Aziz. "Antioxidant potential study of some synthesized N-heterocycles." Bangladesh Medical Research Council Bulletin 35, no. 2 (2009): 49–52. http://dx.doi.org/10.3329/bmrcb.v35i2.2564.

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Nitrogen containing heterocyclic compounds such as oxindoles especially isatins and their derivatives have excellent biological properties such as anti-inflammatory, antimicrobial, anticancer activity. In addition, this is first time ever we would like to report the antioxidant properties of the said class of compounds. To determine such an important bioactivity a number of halogenated oxindoles 1-3, their diaza-biphenyl derivatives (4-6), ring extended biphenyl (7) and bis-amide (8) were synthesized by classical heating method. The antioxidant activity of all the synthesized compounds was scr
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Patrauchan, Marianna A., Christine Florizone, Shawn Eapen, et al. "Roles of Ring-Hydroxylating Dioxygenases in Styrene and Benzene Catabolism in Rhodococcus jostii RHA1." Journal of Bacteriology 190, no. 1 (2007): 37–47. http://dx.doi.org/10.1128/jb.01122-07.

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ABSTRACT Proteomics and targeted gene disruption were used to investigate the catabolism of benzene, styrene, biphenyl, and ethylbenzene in Rhodococcus jostii RHA1, a well-studied soil bacterium whose potent polychlorinated biphenyl (PCB)-transforming properties are partly due to the presence of the related Bph and Etb pathways. Of 151 identified proteins, 22 Bph/Etb proteins were among the most abundant in biphenyl-, ethylbenzene-, benzene-, and styrene-grown cells. Cells grown on biphenyl, ethylbenzene, or benzene contained both Bph and Etb enzymes and at least two sets of lower Bph pathway
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