Academic literature on the topic 'Bipolar disorder, burden, course'

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Journal articles on the topic "Bipolar disorder, burden, course"

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Treuer, T., and M. Tohen. "Predicting the course and outcome of bipolar disorder: A review." European Psychiatry 25, no. 6 (2010): 328–33. http://dx.doi.org/10.1016/j.eurpsy.2009.11.012.

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AbstractDespite of advances in pharmacological and non-pharmacological treatments, bipolar disorder often entails multiple relapses and impaired psychological functioning. The extent to which modern treatments have influenced the natural course of a mental disorder is uncertain. Prediction of the course and outcome of bipolar disorders continues to be challenging, despite the multiple research efforts worldwide. Due to a lack of laboratory diagnostic tests and biomarkers, psychiatric interview and examination provide the basis for outcome prediction. While considered to have more favorable pro
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Wittchen, Hans-Ulrich, Stephan Mühlig, and Lukas Pezawas. "Natural course and burden of bipolar disorders." International Journal of Neuropsychopharmacology 6, no. 2 (2003): 145–54. http://dx.doi.org/10.1017/s146114570300333x.

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McIntyre, Roger. "Bipolar Disorder and ADHD: Clinical Concerns." CNS Spectrums 14, S6 (2009): 8–9. http://dx.doi.org/10.1017/s1092852900024822.

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During the past decade, a similar composite has emerged for both bipolar disorder and adult attention-deficit/hyperactive disorder (ADHD). First, both conditions have a relatively high prevalence, a low case detection, a protracted illness course, a high rate of comorbidity, multifactorial ideology, substantial heritable liability, and tremendous burden of illness in economic cost as well as interpersonal and vocational maladjustments. What has also been interesting along with these reports is that there has been emerging scientific studies implicating common brain regions and neural circuits
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Bermúdez-Ampudia, C., A. García-Alocén, M. Martínez-Cengotitabengoa, et al. "Mixed-effects models: Family burden and functionality in patients with bipolar disorder." European Psychiatry 33, S1 (2016): S331. http://dx.doi.org/10.1016/j.eurpsy.2016.01.1147.

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IntroductionThe bipolar disorder (BD) has an important effect over the lives of patients and families. The attitude of the family is a modifiable factor through specific interventions and it has been related with BD prognosis.ObjectivesStudy a sample of families and patients with BD.AimsCompare between two groups its course of burden of caring for family members with BD. Also, we will see the course of the functionality in patients.MethodsSample of 148 individuals who caring a familiar with BD. Seventy-six of these followed psychoeducation session are going to be experimental group (EG), and t
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Forty, Liz, Anna Ulanova, Lisa Jones, et al. "Comorbid medical illness in bipolar disorder." British Journal of Psychiatry 205, no. 6 (2014): 465–72. http://dx.doi.org/10.1192/bjp.bp.114.152249.

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BackgroundIndividuals with a mental health disorder appear to be at increased risk of medical illness.AimsTo examine rates of medical illnesses in patients with bipolar disorder (n = 1720) and to examine the clinical course of the bipolar illness according to lifetime medical illness burden.MethodParticipants recruited within the UK were asked about the lifetime occurrence of 20 medical illnesses, interviewed using the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) and diagnosed according to DSM-IV criteria.ResultsWe found significantly increased rates of several medical illnesses
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Coryell, W., J. Fiedorowicz, D. Solomon, and J. Endicott. "Age transitions in the course of bipolar I disorder." Psychological Medicine 39, no. 8 (2009): 1247–52. http://dx.doi.org/10.1017/s0033291709005534.

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BackgroundThis analysis aimed to show whether symptoms of either pole change in their persistence as individuals move through two decades, whether such changes differ by age grouping, and whether age of onset plays an independent role in symptom persistence.MethodParticipants in the National Institute of Mental Health (NIMH) Collaborative Depression Study (CDS) who completed at least 20 years of follow-up and who met study criteria for bipolar I or schizo-affective manic disorder, before intake or during follow-up, were divided by age at intake into youngest (18–29 years, n=56), middle (30–44
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Rakofsky, Jeffrey J., Steven T. Levy, and Boadie W. Dunlop. "Conceptualizing Treatment Nonadherence in Patients with Bipolar Disorder and PTSD." CNS Spectrums 16, no. 1 (2011): 11–20. http://dx.doi.org/10.1017/s1092852912000119.

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AbstractTreatment nonadherence is a concern among patients with bipolar disorder and posttraumatic stress disorder (PTSD). PTSD is common among patients with bipolar disorder and those with this comorbidity often have a more severe course of illness. While many factors have been associated with nonadherence in bipolar disorder patients and in PTSD patients, almost no research has focused on the factors associated with non-adherence in bipolar disorder patients with comorbid PTSD. Studies in primary bipolar disorder samples reveal patient, illness, drug and clinician characteristics associated
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GOIKOLEA, J. M., F. COLOM, A. MARTÍNEZ-ARÁN, et al. "Clinical and prognostic implications of seasonal pattern in bipolar disorder: a 10-year follow-up of 302 patients." Psychological Medicine 37, no. 11 (2007): 1595–99. http://dx.doi.org/10.1017/s0033291707000864.

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ABSTRACTBackgroundMore than 20% of bipolar patients may present with seasonal pattern (SP). Seasonality can alter the course of bipolar disorder. However, to date, long-term follow-up studies of bipolar patients presenting with SP are scarce. We present a 10-year follow-up study comparing clinical and demographic features of bipolar patients with and without SP.MethodThree hundred and twenty-five bipolar I and II patients were followed up for at least 10 years. SP was defined according to DSM-IV criteria. Clinical variables were obtained from structured interviews with the patients and their r
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Muralidharan, Kesavan, Ivan J. Torres, Leonardo E. Silveira, et al. "Impact of depressive episodes on cognitive deficits in early bipolar disorder: data from the Systematic Treatment Optimization Programme for Early Mania (STOP-EM)." British Journal of Psychiatry 205, no. 1 (2014): 36–43. http://dx.doi.org/10.1192/bjp.bp.113.135525.

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BackgroundAlthough manic episodes reportedly contribute to cognitive deficits in bipolar I disorder, the contribution of depressive episodes is poorly researched.AimsWe investigated the impact of depressive episodes on cognitive function early in the course of bipolar I disorder.MethodA total of 68 patients and 38 controls from the Systematic Treatment Optimization Programme for Early Mania (STOP-EM) first-episode mania programme were examined. We conducted (a) a cross-sectional analysis of the impact of prior depressive episodes on baseline cognitive function and (b) a prospective analysis as
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Bilska, Karolina, Joanna Pawlak, Paweł Kapelski, et al. "Differences in the Clinical Picture in Women with a Depressive Episode in the Course of Unipolar and Bipolar Disorder." Journal of Clinical Medicine 10, no. 4 (2021): 676. http://dx.doi.org/10.3390/jcm10040676.

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Due to current depression prevalence, it is crucial to make the correct diagnosis as soon as possible. The study aimed to identify commonly available, easy to apply, and quick to interpret tools allowing for a differential diagnosis between unipolar and bipolar disorder. The study group includes women with long duration of unipolar (UP, N = 34) and bipolar (BP, N = 43) affective disorder. The diagnosis was established according to the DSM criteria using SCID questionnaire. Additional questionnaires were used to differentiate between UP and BP. BP patients had an earlier age of onset, were hosp
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Dissertations / Theses on the topic "Bipolar disorder, burden, course"

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Wittchen, Hans-Ulrich, Stephan Mühlig, and Lukas Pezawas. "Natural course and burden of bipolar disorders." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-117282.

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Despite an abundance of older and more recent retrospective and considerably fewer prospective-longitudinal studies in bipolar disorders I and II, there are still remarkable deficits with regard to our knowledge about the natural course and burden. The considerable general and diagnosis-specific challenges posed by the nature of bipolar disorders are specified, highlighting in particular problems in diagnostic and symptom assessment, shifts in diagnostic conventions and the broadening of the diagnostic concept by including bipolar spectrum disorders. As a consequence it still remains difficult
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Wittchen, Hans-Ulrich, Stephan Mühlig, and Lukas Pezawas. "Natural course and burden of bipolar disorders." Technische Universität Dresden, 2003. https://tud.qucosa.de/id/qucosa%3A27010.

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Despite an abundance of older and more recent retrospective and considerably fewer prospective-longitudinal studies in bipolar disorders I and II, there are still remarkable deficits with regard to our knowledge about the natural course and burden. The considerable general and diagnosis-specific challenges posed by the nature of bipolar disorders are specified, highlighting in particular problems in diagnostic and symptom assessment, shifts in diagnostic conventions and the broadening of the diagnostic concept by including bipolar spectrum disorders. As a consequence it still remains difficult
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Smith, Patrick (Patrick M. ). "Medical Comorbidity in the Course of Bipolar Disorder." Thesis, University of North Texas, 2016. https://digital.library.unt.edu/ark:/67531/metadc849606/.

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Bipolar disorder is a serious illness affecting approximately 2-4% of the population and is one of the world’s leading causes of disability. In individuals with bipolar disorder, medical comorbidity associated with cardiovascular, respiratory and endocrine disorders is related to increased rates of mortality. Recent updates to multi-system inflammatory related conceptualizations of bipolar disorder focus on the unique power that medical illness and biological processes may play as factors associated with course and outcome in bipolar disorder. The current study examined medical comorbidity and
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Kim, Eunice Y. "Life stress and the course of early-onset bipolar disorder." Diss., Connect to online resource, 2005. http://wwwlib.umi.com/dissertations/fullcit/3178325.

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Pini, Stefano, Queiroz Valéria de, Daniel Pagnin, et al. "Prevalence and burden of bipolar disorders in European countries." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-110193.

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A literature search, supplemented by an expert survey and selected reanalyses of existing data from epidemiological studies was performed to determine the prevalence and associated burden of bipolar I and II disorder in EU countries. Only studies using established diagnostic instruments based on DSM-III-R or DSM-IV, or ICD-10 criteria were considered. Fourteen studies from a total of 10 countries were identified. The majority of studies reported 12-month estimates of approximately 1% (range 0.5–1.1%), with little evidence of a gender difference. The cumulative lifetime incidence (two prospecti
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Prichard, Adrine Biuckians m. d. "Anxiety, mood symptoms, and the course of early-onset bipolar disorder." Connect to online resource, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3315762.

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Pini, Stefano, Queiroz Valéria de, Daniel Pagnin, et al. "Prevalence and burden of bipolar disorders in European countries." Technische Universität Dresden, 2005. https://tud.qucosa.de/id/qucosa%3A26819.

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A literature search, supplemented by an expert survey and selected reanalyses of existing data from epidemiological studies was performed to determine the prevalence and associated burden of bipolar I and II disorder in EU countries. Only studies using established diagnostic instruments based on DSM-III-R or DSM-IV, or ICD-10 criteria were considered. Fourteen studies from a total of 10 countries were identified. The majority of studies reported 12-month estimates of approximately 1% (range 0.5–1.1%), with little evidence of a gender difference. The cumulative lifetime incidence (two prospecti
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Bain, Kathleen Marie. "Eight-Year Course of Cognitive Functioning in Bipolar Disorder with Psychotic Features." Thesis, University of North Texas, 2016. https://digital.library.unt.edu/ark:/67531/metadc862811/.

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The purpose of the current study was to examine neuropsychological functioning in patients with bipolar disorder (BD) with psychotic features. Data from a large, epidemiological study of patients with first-episode psychosis was used to examine verbal learning and working memory 10 years after onset of psychosis in patients with BD relative to patients with schizophrenia (SZ) and patients with psychotic major depressive disorder (MDD). Cross-sectional comparisons of verbal learning and working memory at the 10-year follow-up mirrored findings of relative performance at the 2-year follow-up (Mo
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Fiedorowicz, Jess G. "Course of illness and the development of vascular disease in individuals with bipolar disorder." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/2699.

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For over a century, there have been suggestions of a link between what is currently called bipolar disorder and cardiovascular mortality. In the contemporary epidemiological literature, this risk has been confirmed and approximates twice that expected based on age and gender. To date, however, this information has come primarily from clinical samples, which carry considerable risk of selection bias. The studies contained in this dissertation sought to assess this relationship using methods less vulnerable to selection bias and to determine the role that course of illness and treatments for ill
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Vesco, Anthony Thomas. "Examining the Course of Cyclothymic Disorder and Comparing it to Dysthymic Disorder and Other Bipolar Spectrum Disorders in Children." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1364907946.

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Books on the topic "Bipolar disorder, burden, course"

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Balzafiore, Danielle, Thalia Robakis, Sarah Borish, Vena Budhan, and Natalie Rasgon. The treatment of bipolar disorder in women. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0020.

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Sex-specific effects in the clinical presentation and course of bipolar disorder in women have important treatment implications for the management of symptoms across the menstrual cycle and reproductive lifespan. Women with bipolar disorder are particularly vulnerable to premenstrual mood symptoms, menstrual abnormalities, and polycystic ovary syndrome. Special considerations include understanding the interactions between these reproductive issues, oral contraceptives, and mood-stabilizing agents. Additionally, the management of bipolar disorder during the perinatal period requires a careful a
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Bipolar disorders: Clinical course and outcome. American Psychiatric Press, 1999.

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(Editor), Joseph F. Goldberg, and Martin Harrow (Editor), eds. Bipolar Disorders: Clinical Course and Outcome (Clinical Practice). American Psychiatric Publishing, Inc., 1999.

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Youngstrom, Eric, and Anna Van Meter. Comorbidity of Bipolar Disorder and Depression. Edited by C. Steven Richards and Michael W. O'Hara. Oxford University Press, 2013. http://dx.doi.org/10.1093/oxfordhb/9780199797004.013.003.

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There has been speculation about the relationship between depression and mania for centuries. Modern psychiatry and psychology have mostly viewed these as different subtypes within a “family” of mood disorders. Conceptual models of comorbidity provide an opportunity to re-examine the association between depression and other pathological mood states. We examine the evidence pertaining to rates of “comorbidity,” which, in this case, refer to the lifetime occurrence of depression and hypomanic, mixed, or manic episodes in the same individual. We explore factors that could contribute to artifactua
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Henter, Ioline D., and Rodrigo Machado-Vieira. Novel therapeutic targets for bipolar disorder. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0030.

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The long-term course of bipolar disorder (BD) comprises recurrent depressive episodes and persistent residual symptoms for which standard therapeutic options are scarce and often ineffective. Glutamate is the major excitatory neurotransmitter in the central nervous system, and glutamate and its cognate receptors have consistently been implicated in the pathophysiology of mood disorders and in the development of novel therapeutics for these disorders. Since the rapid and robust antidepressant effects of the N-methyl-D-aspartate (NMDA) antagonist ketamine were first observed in 2000, other NMDA
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Fountoulakis, Konstantinos N., and Dimos Dimellis. The treatment of rapid cycling bipolar disorder. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0006.

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Rapid cycling may complicate the course of a significant proportion of patients with bipolar disorder (BD). It is defined in DSM-5 by the occurrence of at least four distinct mood episodes in 12 months. Rapid cycling BD has been consistently associated with worse outcomes compared with non-rapid cycling BD. Thus, rapid cycling BD may require specific treatment strategies. Antidepressants, antipsychotics, and mood stabilizers/anticonvulsants have been studied either as monotherapy or in combination treatments. Concerning the treatment of acute mood episodes, the best available data exist for at
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Milev, Roumen. The role of electroconvulsive therapy in the treatment of bipolar disorder. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0027.

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This chapter examines the use of electroconvulsive therapy (ECT) for treatment of patients with bipolar disorders. It briefly reviews the basics of ECT, stimulus parameters, placement of electrodes, and seizure threshold. The data for efficacy and tolerability of ECT for bipolar disorder, including mania, depression, mixed states, and across the lifespan is reviewed. Although there is a paucity of good-quality randomized studies, all available data, including case reports and naturalistic observations, support the use of ECT in this population, and reinforce the widespread use of ECT in everyd
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Cavalcante Passos, Ives, and Flávio Kapczinski. Staging and neuroprogression in bipolar disorder: treatment implications. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0024.

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It is known that if, not all, a substantial proportion of patients with bipolar disorder (BD) present a progressive course with functional and cognitive impairment. In addition, patients with BD and multiple mood episodes have a worse response to lithium and cognitive behaviour therapy. However, many current treatment guidelines do not take these clinical features that change with illness progression into account. In order to clarify these clinical questions, the term ‘neuroprogression’ was conceptualized as the pathological rewiring of the brain that takes place in parallel with the clinical
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Fabbri, Chiara, and Alessandro Serretti. The treatment of bipolar disorder in the era of personalized medicine: myth or promise? Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0031.

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Bipolar disorder (BD) is a chronic disease associated with high personal and socio-economic burden. Genetics accounts for 20–95% of variability in central nervous system drug disposition and pharmacodynamics, thus genetic markers are considered a promising way to develop tailored treatments and improve the prognosis of the disease. Among mood stabilizers, lithium response was the most investigated phenotype and the most replicated genes are involved in synaptic plasticity (BDNF), serotonergic (SLC6A4) and dopaminergic (DRD1) neurotransmission, and second messenger cascades (GSK3B). Relevant ph
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da Costa, Sabrina C., Joao L. de Quevedo, and André F. Carvalho. Predominant polarity, polarity index, and treatment selection in bipolar disorder. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0015.

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Bipolar disorder (BD) is a chronic and disabling illness, with lifetime prevalence of 2.4% worldwide. Predominant polarity (PP), ie, depressive versus manic, may influence illness characteristics, treatment selection, and outcomes in BD. PP has been proposed as a course specifier for BD, although not included in the Diagnostic and Statistical Manual of Mental Disorders (5th edn) (DSM-5). The polarity index (PI), a metric algorithm that reflects antimanic versus antidepressant maintenance efficacy of available treatments for BD, is calculated as the ratio of number needed to treat (NNT) for pre
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Book chapters on the topic "Bipolar disorder, burden, course"

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Fountoulakis, Kostas N. "Long-Term Course." In Bipolar Disorder. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-37216-2_3.

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Goldberg, Joseph F., and Carrie L. Ernst. "The Economic and Social Burden of Bipolar Disorder." In Bipolar Disorder. John Wiley & Sons, Ltd, 2002. http://dx.doi.org/10.1002/047084650x.ch6.

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Fountoulakis, Kostas N. "Disability and Overall Burden Related with Bipolar Disorder." In Bipolar Disorder. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-37216-2_12.

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Judd, Lewis L., and Pamela J. Schettler. "The Long-Term Course and Clinical Management of Bipolar I and Bipolar II Disorders." In Bipolar Disorder. John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470661277.ch3.

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Mitchell, Philip B., Dusan Hadzi-Pavlovic, and Colleen K. Loo. "Course and Outcome of Bipolar Disorder." In Behavioral Neurobiology of Bipolar Disorder and its Treatment. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/7854_2010_66.

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Angst, J. "The Course of Major Depression, Atypical Bipolar Disorder, and Bipolar Disorder." In New Results in Depression Research. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70702-5_4.

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Vieta, Eduard. "Etiology and Disease Course." In Managing Bipolar Disorder in Clinical Practice. Springer Healthcare Ltd., 2013. http://dx.doi.org/10.1007/978-1-908517-94-4_3.

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Clayton, P. J. "Clinical Picture and Course of Bipolar Affective Disorder." In Contemporary Psychiatry. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-59519-6_99.

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Bauer, Michael, and Michael Gitlin. "Natural Course of Bipolar Disorder and Implications for Treatment." In The Essential Guide to Lithium Treatment. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-31214-9_2.

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Escalona, Rodrigo, and Mauricio Tohen. "Course and Outcome of Bipolar Disorder: Focus on Depressive Aspects." In Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis, and Pharmacotherapy. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-31689-5_3.

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