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Journal articles on the topic 'Bis-heterocycles'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

Luo, Gou-Wei, Chien-Yu Hu, Zih-Yang Lei, Gene-Hsiang Lee, and Chung K. Lai. "H–bonded mesogenic unsymmetric bis-heterocycles." Journal of Molecular Liquids 261 (July 2018): 76–88. http://dx.doi.org/10.1016/j.molliq.2018.03.095.

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2

Sayed, Osama M., H. Moustafa, Ahmed E. M. Mekky, Ahmad M. Farag, and Ahmed H. M. Elwahy. "Synthesis, reactions and DFT calculations of novel bis(chalcones) linked to a thienothiophene core through an oxyphenyl bridge." RSC Advances 6, no. 13 (2016): 10949–61. http://dx.doi.org/10.1039/c5ra27322f.

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3

Basavanag, Unnamatla M. V., Alejandro Islas-Jácome, Angel Rentería-Gómez, et al. "Synthesis of 2-julolidin-imidazo[1,2-a]pyridines via Groebke–Blackburn–Bienaymé reaction and studies of optical properties." New Journal of Chemistry 41, no. 9 (2017): 3450–59. http://dx.doi.org/10.1039/c6nj04044f.

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4

Lin, Kuan-Ting, Gene-Hsiang Lee, and Chung K. Lai. "Mesogenic heterocycles formed by bis-pyrazoles and bis-1,3,4-oxadiazoles." Tetrahedron 71, no. 25 (2015): 4352–61. http://dx.doi.org/10.1016/j.tet.2015.04.055.

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5

Boelke, Andreas, Soleicha Sadat, Enno Lork, and Boris J. Nachtsheim. "Pseudocyclic bis-N-heterocycle-stabilized iodanes – synthesis, characterization and applications." Chemical Communications 57, no. 60 (2021): 7434–37. http://dx.doi.org/10.1039/d1cc03097c.

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6

Wu, Chao, та Peng Cao. "Crystal structure of poly[diaqua(μ2-benzene-1,4-dicarboxylato-κ2O1:O4)(μ2-benzene-1,4-dicarboxylato-κ4O1,O1′:O4,O4′)bis(μ2-3,3′,5,5′-tetramethyl-4,4′-bipyrazole-κ2N:N′)dinickel(II)]". Acta Crystallographica Section E Crystallographic Communications 71, № 6 (2015): m127—m128. http://dx.doi.org/10.1107/s2056989015008415.

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The asymmetric unit of the polymeric title compound, [Ni(C8H4O4)(C10H14N4)(H2O)]n, contains one Ni2+cation, one coordinating water molecule, one 3,3′,5,5′-tetramethyl-4,4′-bipyrazole ligand and half each of two benzene-1,4-dicarboxylate anions, the other halves being generated by inversion symmetry. The Ni2+cation exhibits an octahedral N2O4coordination sphere defined by the O atoms of the water molecule and two different anions and the N atoms of two symmetry-relatedN-heterocycles. TheN-heterocycles and both anions bridge adjacent Ni2+cations into a three-dimensional network structure, with o

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7

Alvarez-Rodríguez, Nancy V., Alejandro Islas-Jácome, Angel Rentería-Gómez, Luis E. Cárdenas-Galindo, M. V. Basavanag Unnamatla, and Rocío Gámez-Montaño. "Synthesis of 1′-tetrazolylmethyl-spiro[pyrrolidine-3,3′-oxindoles] via two coupled one-pot processes Ugi-azide/Pictet–Spengler and oxidative spiro-rearrangement." New Journal of Chemistry 42, no. 3 (2018): 1600–1603. http://dx.doi.org/10.1039/c7nj03829a.

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8

Almendros, Pedro, Hikaru Yanai, Shoki Hoshikawa, et al. "Transition metal-free controlled synthesis of bis[(trifluoromethyl)sulfonyl]ethyl-decorated heterocycles." Organic Chemistry Frontiers 5, no. 21 (2018): 3163–69. http://dx.doi.org/10.1039/c8qo00955d.

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9

Elwahy, Ahmed H. M., та Ashraf A. Abbas. "Bis(β-Difunctional) Compounds: Versatile Starting Materials for Novel Bis(Heterocycles)". Synthetic Communications 30, № 16 (2000): 2903–21. http://dx.doi.org/10.1080/00397910008087441.

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10

Pecorari, Daniel, Andrea Mazzanti, Stefano Gianvittorio, et al. "Highly twisted carbazole-borane derivatives: B–N stereodynamic analysis and consequences on their emission properties." Organic Chemistry Frontiers 8, no. 16 (2021): 4496–507. http://dx.doi.org/10.1039/d1qo00715g.

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11

Nguyen, Thi Thu Tram, Le Anh Nguyen, Quoc Anh Ngo, Marina Koleski, and Thanh Binh Nguyen. "The catalytic role of elemental sulfur in the DMSO-promoted oxidative coupling of methylhetarenes with amines: synthesis of thioamides and bis-aza-heterocycles." Organic Chemistry Frontiers 8, no. 7 (2021): 1593–98. http://dx.doi.org/10.1039/d0qo01654c.

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12

Austin, Martin, Kassu Gebreyes, Henry G. Kuivila, Kamal Swami, and Jon A. Zubieta. "Complexes of bis-(chlorodimethylstannyl)- and bis(dichloromethylstannyl)methanes with aromatic nitrogen heterocycles." Organometallics 6, no. 4 (1987): 834–42. http://dx.doi.org/10.1021/om00147a024.

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13

M. Farag, Ahmad, Mohamed A. Elsayed, and Korany A. Ali. "Synthesis of Some New Pyridine-2,6-bis-heterocycles." HETEROCYCLES 85, no. 8 (2012): 1913. http://dx.doi.org/10.3987/com-12-12483.

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14

Li, Yu-Lun, Gene-Hsiang Lee, and Chung K. Lai. "Mesogenic bis-heterocycles incorporating both pyrazole and isoxazole." Tetrahedron 71, no. 33 (2015): 5296–307. http://dx.doi.org/10.1016/j.tet.2015.06.021.

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15

Shivakumaraiah and Nadur M. Nanje Gowda. "Studies on Palladium(II) Complexes Containing Multidentate N-heterocycles." Journal of Chemical Research 2005, no. 8 (2005): 505–7. http://dx.doi.org/10.3184/030823405774663381.

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Palladium dihalides/perchlorate react with the multidentate N-heterocycles (I), 1,3-bis(benzimidazol-2-yl)benzene (L1) 1,3-bis(1-methylbenzimidazol-2-yl)benzene (L2), 2,6-bis(benzimidazol-2-yl)pyridine (L3) and 2,6-bis(1-methylbenzimidazol-2-yl) pyridine (L4) in ethanol/tetrahydrofuran in presence of hydrohalic acid to yield complexes of the compositions, [PdX2L·nH2O] (X = Cl, L = L1 or L2, n = 1; X = Cl, L = L3 or L4, n = 0; X = Br, L = L1 or L3 n = 0; X = Br, L = L2, n = 3; X = Br, L = L4, n = 2), PdL2(ClO4)2·nH2O (L = L1, n = 2; L = L2, n = 1) and [Pd2L3(ClO4)4·nH2O] (L = L3, n = 2; L = L4,

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16

Hermannsdorfer, André, Douglas W. Stephan, and Matthias Driess. "Taming a silyldiium cation and its reactivity towards sodium phosphaethynolate." Chemical Communications 54, no. 96 (2018): 13523–26. http://dx.doi.org/10.1039/c8cc07632d.

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17

Ebrahimlo, Ali Reza Molla, Jabbar Khalafy, and Rolf H. Prager. "The Synthesis of Potential DNA Intercalators. 2. Tri- and Tetra-Cyclic Heterocycles." Australian Journal of Chemistry 62, no. 2 (2009): 126. http://dx.doi.org/10.1071/ch08370.

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The reaction of 1,4-dichlorophthalazine and 2,3-dichloroquinoxaline with some isoxazolones gave their mono- and bis-isoxazolinyl derivatives. The base-catalyzed rearrangement of these derivatives afforded the corresponding tri- and tetracyclic heterocycles.

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18

Babu, Sheba Ann, Rajalekshmi A. R., Nitha P. R., et al. "Unprecedented access to functionalized pyrrolo[2,1-a]isoquinolines from the domino reaction of isoquinolinium ylides and electrophilic benzannulated heterocycles." Organic & Biomolecular Chemistry 19, no. 8 (2021): 1807–17. http://dx.doi.org/10.1039/d1ob00005e.

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The reaction between electrophilic benzannulated heterocycles and isoquinolinium methylides results in a domino dipolar cycloaddition-ring opening transformation, generating functionalized pyrrolo[2,1-a]isoquinolines and S–S-bridged bis-pyrrolo[2,1-a]isoquinolines.

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19

Jayashankara, B., and K. M. Lokanatha Rai. "Synthesis and Antimicrobial Studies of a New Series of Bis-Heterocycles." E-Journal of Chemistry 5, no. 2 (2008): 370–76. http://dx.doi.org/10.1155/2008/659752.

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Series of novel bis-heterocycles bearing isoxazoline and imidazole moieties have been synthesizedvia1,3-dipolarcycloaddition reactions.1HNMR,13CNMR, IR and elemental analyses characterized the newly synthesized compounds. All the synthesized compounds were evaluated for their antimicrobial activity and were compared with the standard drugs. The compounds demonstrated potent to weak antimicrobial activity.

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20

Manuylov, Viktor, Valentina Nikonova, Igor' Rozencveyg, and Nikolay Korchevin. "BIS(2-CHLOROPROPENYL)SULFIDE HETEROCYCLIZATION UNDER THE ACTION OF CHALCOGENS IN HYDRAZINE HYDRATE–KOH." Modern Technologies and Scientific and Technological Progress 1, no. 1 (2021): 51–53. http://dx.doi.org/10.36629/2686-9896-2021-1-1-51-53.

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The sense of bis(2-chloropropenyl)sulfide heterocyclization at its interaction with  sulfur, selen and tellur in the hydrazine hydrate–KOH system has been studied. The suggest plausible  mechanism of different heterocycles formation is discussed.

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21

Muhammad, Zeinab A., Fatimah Alshehrei, Mohie E. M. Zayed, Thoraya A. Farghaly, and Magda A. Abdallah. "Synthesis of Novel Bis-pyrazole Derivatives as Antimicrobial Agents." Mini-Reviews in Medicinal Chemistry 19, no. 15 (2019): 1276–90. http://dx.doi.org/10.2174/1389557519666190313095545.

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Background: bis-heterocycles especially those containing pyrazole moiety display much better antibacterial activity than mono heterocycles. Objective: Herein, we synthesised a series of new bis-pyrazoles and investigated their antimicrobial agents. Methods: A novel series of bis-pyrazole derivatives have been synthesized in good yield by coupling reaction of cyanoacetic acid 4-[(2-cyano-acetyl)-hydrazonomethyl]-benzylidene-hydrazide with a number of diazonium salts of aromatic amines in DMF in the presence of NaOH. Refluxing of the produced hydrazones with hydrazine-hydrate in ethanolic soluti

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22

Kvyatkovskaya, Elizaveta A., Polina P. Epifanova, Eugeniya V. Nikitina, et al. "Synthesis and ethylene-promoted metathesis of adducts of tandem [4+2]/[4+2] cycloaddition between bis-furyl dienes and maleic acid derivatives." New Journal of Chemistry 45, no. 7 (2021): 3400–3407. http://dx.doi.org/10.1039/d0nj04528d.

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A series of 1,4:5,8-diepoxynaphthalenes, annellated with carbo- and heterocycles, was synthesized based on the tandem intermolecular/intramolecular [4+2] cycloaddition of bis-furyl dienes with moderately to highly reactive cyclic dienophiles (maleic anhydride and maleinimides).

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23

Singh, Prabal, S. Yugandar, S. Kumar, H. Ila, and H. Junjappa. "Synthesis of Novel Five- and Six-Membered Ferrocene-Containing Heterocycles and Heteroaromatics via Cyclocondensation of 1-Ferrocenyl-3,3-bis(methylthio)prop-2-en-1-one with Various Bifunctional Nucleophiles." Synthesis 49, no. 12 (2017): 2700–2710. http://dx.doi.org/10.1055/s-0036-1588966.

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Synthesis and reactions of 1-ferrocenyl-3,3-bis(methylthio)prop-2-en-1-one as a versatile 1,3-bielectrophilic synthon leading to a range of novel ferrocene-containing five- and six-membered heterocycles and heteroaromatics has been reported. Thus its cyclocondensation with various bifunctional heteronucleophiles, such as hydrazine, phenylhydrazine, hydroxylamine, guanidine, and amidine, affords a range of ferrocene-substituted pyrazoles, oxazoles, and pyrimidines in highly regioselective manner. Synthesis of few ferrocenyl-substituted pyridines and thiophenes has also been described. Similar

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24

Padmavathi, Venkatapuram, Boggu Jagan Mohan Reddy, Konda Mahesh, Pinnu Thriveni, and Adivireddy Padmaja. "E,E-Bis(styryl)sulfones-Synthons for a new class of bis(heterocycles)." Journal of Heterocyclic Chemistry 47, no. 4 (2010): 825–30. http://dx.doi.org/10.1002/jhet.332.

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25

Elwahy, Ahmed H. M., та Ashraf A. Abbas. "ChemInform Abstract: Bis(β-difunctional) Compounds: Versatile Starting Materials for Novel Bis(heterocycles)." ChemInform 31, № 49 (2000): no. http://dx.doi.org/10.1002/chin.200049040.

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26

Mayooufi, A., M. Romdhani-Younes, and J. Thibonnet. "Efficient One-Pot Synthesis of Triazole-Linked Morpholinone Scaffolds by CuAAC in the Presence of 18-Crown-6." SynOpen 02, no. 04 (2018): 0298–305. http://dx.doi.org/10.1055/s-0037-1610399.

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A range of bis-heterocyclic derivatives based on novel morpholinone and triazole heterocycles was prepared from iodo-morpholinone. The key step in our strategy is a one-pot procedure based upon copper-catalysed alkyne-azide cycloaddition (CuAAC) from iodo-morpholinone.

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27

Al-Timari, Usama A. R., Lubor Fišera, and Naďa Prónayová. "1,3-Dipolar Cycloadditions of Aromatic Nitrile Oxides and Nitrones to 1,1'-(Methylenedi-4,1-phenylene)bismaleimide." Collection of Czechoslovak Chemical Communications 57, no. 9 (1992): 1982–92. http://dx.doi.org/10.1135/cccc19921982.

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Within the scope of our research aimed at utilization of 1,3-dipolar cycloaddition reactions to heterocycles as well as to pesticide programme we report the 1,3-dipolar cycloaddition of nitrile oxides II, III and nitrones V to bis-maleiimide derivative I.

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28

M. Abadleh, Mohammed, Mustafa M. El-Abadelah, Firas F. Awwadi, and Monther S. Zreid. "Bis-Heterocycles. Part II. Tetrahydro-3,3'-bi(1,2,4,5-oxatriazines)." HETEROCYCLES 98, no. 2 (2019): 205. http://dx.doi.org/10.3987/com-18-14015.

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29

Pieczonka, Adam M., and Grzegorz Mlostoń. "Synthesis of Enantiopure Bis-Heterocycles Derived from (S)-Prolinehydrazides." Phosphorus, Sulfur, and Silicon and the Related Elements 188, no. 4 (2013): 493–95. http://dx.doi.org/10.1080/10426507.2012.738737.

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30

Sanford, Gabrielle, Kaitlynn E. Walker, Frank R. Fronczek, and Thomas Junk. "Novel Organotellurium Heterocycles Derived From Bis(2-Aminophenyl) Ditelluride." Journal of Heterocyclic Chemistry 54, no. 1 (2016): 575–79. http://dx.doi.org/10.1002/jhet.2624.

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31

Mahaboob Basha, Nabhubygari, Dandu Seenaiah, Adivireddy Padmaja, Venkatapuram Padmavathi, Desaraju Suresh Bhargav, and Tartte Vijaya. "Synthesis and Antioxidant Activity of Bis and Tris Heterocycles." Archiv der Pharmazie 347, no. 1 (2013): 54–67. http://dx.doi.org/10.1002/ardp.201300290.

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32

HASSNER, A., and B. FISCHER. "ChemInform Abstract: Novel Heterocycles by Bis Heteroannulation of Oxazoles." ChemInform 22, no. 39 (2010): no. http://dx.doi.org/10.1002/chin.199139146.

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33

Pieczonka, Adam M., Grzegorz Mlostoń, Anthony Linden, and Heinz Heimgartner. "New Optically Active Bis-Heterocycles Derived from (S)-Proline." Helvetica Chimica Acta 95, no. 9 (2012): 1521–30. http://dx.doi.org/10.1002/hlca.201200400.

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34

Rajasekhar, Chittoor, Suram Durgamma, and Adivireddy Padmaja. "E-Aroylethenesulfonylacetic Acid Methyl Ester: Source for Bis Heterocycles." Journal of Heterocyclic Chemistry 51, no. 6 (2014): 1727–34. http://dx.doi.org/10.1002/jhet.1862.

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35

Maringgele, Walter, Mathias Noltemeyer, and Anton Meller. "Bis(diorganylamino)dihalodiboroxanes as Building Blocks for Boron Heterocycles†." Organometallics 16, no. 11 (1997): 2276–84. http://dx.doi.org/10.1021/om960933x.

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36

Padmavathi, Venkatapuram, B. Jagan Mohan Reddy, and D. R. C. Venkata Subbaiah. "Bischalcones—synthons for a new class of bis(heterocycles)." New J. Chem. 28, no. 12 (2004): 1479–83. http://dx.doi.org/10.1039/b409968k.

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37

Hassner, A., and B. Fischer. "Cycloadditions. 48. Novel heterocycles by bis heteroannulation of oxazoles." Journal of Organic Chemistry 56, no. 10 (1991): 3419–25. http://dx.doi.org/10.1021/jo00010a044.

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38

Li, Jun-Fei, Hai-Bin Song, You-Quan Zhu, and Hua-Zheng Yang. "Ethyl 1-[5-amino-1-tert-butyl-3-(methylsulfanyl)-1H-pyrazole-4-carbonyl]-5-methyl-3-(methylsulfanyl)-1H-pyrazole-4-carboxylate." Acta Crystallographica Section E Structure Reports Online 62, no. 5 (2006): o1679—o1681. http://dx.doi.org/10.1107/s1600536806011500.

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The title molecule, C17H25N5O3S2, belongs to the family of bis-heterocycles. In the crystal structure, there are one intra- and two intermolecular hydrogen bonds. One of the two pyrazole rings and the six-membered ring formed by the intramolecular hydrogen bond are approximately coplanar.

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39

Chavan, Snehal A., Avinash G. Ulhe, and Baliram N. Berad. "Synthesis and characterization of N-glucosylated dithiadiazepine derivatives through carbon-sulfur bond formation." Heterocyclic Communications 21, no. 5 (2015): 269–72. http://dx.doi.org/10.1515/hc-2015-0093.

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AbstractNew 4,7-bis(arylamino)-2-tetra-O-acetyl-β-d-glucopyranosylimino-1,3,5,6-dithiadiazepines were synthesized via reaction of N-tetra-O-acetyl-β-d-glucopyranosyl isocyanodichloride with 1,6-diaryl-2,5-dithio-bis-ureas without using any catalyst. Thus, the synthesis of 7-membered heterocycles containing two sulfur and two nitrogen atoms through carbon-sulfur bond formation was explored. The chemical structures of these new compounds were elucidated by IR, 1H NMR, 13C NMR, mass spectral, and elemental analyses.

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40

Ramírez-López, Sandra C., and Rocío Gámez-Montaño. "Microwave-Assisted Synthesis of Bis-Heterocycles Containing the Imidazo[1,2-a]Pyridine by Groebke-Blackburn-Bienaymé Reaction." Proceedings 41, no. 1 (2019): 79. http://dx.doi.org/10.3390/ecsoc-23-06648.

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A series of six fused bis-heterocycles having imidazo[1,2-a]pyridine bound with quinoline were synthesized by microwave-assisted Groebke-Blackburn-Bienaymé reaction (GBBR) under green catalysis. The GBB products are privileged scaffolds and their synthesis is of great interest in synthetic and medicinal chemistry.

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41

Ram, Vishnu Ji, and H. N. Pandey. "Bis Heterocycles. Part I: Synthesis of Bis(1,2,4-Iriazoles, 1,3,4-Thiadiazoles) and Related Compounds." Bulletin des Sociétés Chimiques Belges 86, no. 5 (2010): 399–403. http://dx.doi.org/10.1002/bscb.19770860509.

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42

Kerschl, Susanna, and Bernd Wrackmeyer. "2,5-Dihydro-1,2,5-azoniastannaboratole: Nützliche Vorstufen für die Heterocyclensynthese / 2,5-Dihydro-1,2,5-azoniastannaboratole: Useful Steps for the Synthesis of Heterocycles." Zeitschrift für Naturforschung B 40, no. 6 (1985): 845–47. http://dx.doi.org/10.1515/znb-1985-0626.

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Abstract Organoboration, Heterocycles, Multinuclear NMR 1,1-Organoboration of diethylamino-dimethyl-(1-propynyl)stannane (6), formed by an exchange reaction between the bis(propynyl)-(4) and bis-(diethylamino)dimethylstannane (5), with trimethyl-(2a) or triethylborane (2b) leads to highly reactive new heterocyclic compounds (7). Both, the coordinative N→B and the weak Sn-N bond are readily attacked by H-acidic compounds. Ammonia or primary amines are used as examples. Multinuclear NMR (1H, 11B, 13C, 15 N, 119Sn) data serve for the characterization.

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43

Pharande, Shrikant G., Manuel A. Rentería-Gómez, and Rocío Gámez-Montaño. "Synthesis of Polyheterocyclic Dimers Containing Restricted and Constrained Peptidomimetics via IMCR-Based Domino/Double CuAAC Click Strategy." Molecules 25, no. 22 (2020): 5246. http://dx.doi.org/10.3390/molecules25225246.

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A novel strategy via the triple process (multicomponent reactions (MCR)-domino)/tandem was developed for the synthesis of restricted and constrained bis-1,2,3-triazole-linked pyrrolo[3,4-b]pyridine peptidomimetics dimers in overall yields of 20–55%. This strategy allows the construction of six heterocycles in two stages of the reaction.

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44

Babu, K. "Synthesis and Antibacterial Studies of 2-Pyrazoline based Bis Heterocycles." Asian Journal of Research in Chemistry 11, no. 2 (2018): 319. http://dx.doi.org/10.5958/0974-4150.2018.00059.7.

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45

Padmavathi, V., B. Jagan Mohan Reddy, B. Chandra Obula Reddy, and A. Padmaja. "Synthesis of a new class of keto-linked bis heterocycles." Tetrahedron 61, no. 9 (2005): 2407–11. http://dx.doi.org/10.1016/j.tet.2005.01.018.

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46

Smith, Christopher D., Kirill Tchabanenko, Robert M. Adlington, and Jack E. Baldwin. "Synthesis of linked heterocycles via use of bis-acetylenic compounds." Tetrahedron Letters 47, no. 19 (2006): 3209–12. http://dx.doi.org/10.1016/j.tetlet.2006.03.052.

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47

Ali, Korany A., Mohamed A. Elsayed, and Ahmad M. Farag. "ChemInform Abstract: Synthesis of Some New Pyridine-2,6-bis-heterocycles." ChemInform 43, no. 49 (2012): no. http://dx.doi.org/10.1002/chin.201249150.

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48

Padmavathi, Venkatapuram, Tumma Sreelatha, Putta Ramachandra Reddy, and Kuppireddygari Divya. "ChemInform Abstract: Synthesis of a New Class of Bis Heterocycles." ChemInform 46, no. 15 (2015): no. http://dx.doi.org/10.1002/chin.201515173.

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49

Babulreddy, A., R. V. Hymavathi, Md Manzoor Hussain, and G. Narayana Swamy. "Synthesis, Characterization, andIn VitroAntimicrobial Activity of Methyleneamine-Linked Bis-heterocycles." Journal of Heterocyclic Chemistry 50, no. 3 (2013): 727–33. http://dx.doi.org/10.1002/jhet.1674.

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50

Babul Reddy, A., R. V. Hymavathi, and G. Narayana Swamy. "Synthesis, Characterization, and Antimicrobial Screening of Ethylene-Spaced Bis-heterocycles." Journal of Heterocyclic Chemistry 51, no. 4 (2014): 1119–23. http://dx.doi.org/10.1002/jhet.1675.

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