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1

Aggarwal, Amulya, Alok V. Mathur, Ram K. Verma, Megha Gupta, and Dheeraj Raj. "Comparison of BISAP and Ranson’s score for predicting severe acute pancreatitis and establish the validity of BISAP score." International Surgery Journal 7, no. 5 (April 23, 2020): 1473. http://dx.doi.org/10.18203/2349-2902.isj20201854.

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Background: Pancreatitis can lead to serious complications with severe morbidity and mortality. So an early, quick and accurate scoring system is necessary to stratify the patients according to their severity so as to enable early initiation of required management and care. Scoring system commonly used have some drawbacks. This study aimed to compare bedside index for severity in acute pancreatitis (BISAP) and Ranson’s score to predict severe acute pancreatitis and establish the validity of a simple and accurate clinical scoring system for stratifying patients.Methods: This is a prospective comparative study on 100 patients diagnosed with acute pancreatitis admitted in department of general surgery. Parameters included in the BISAP and Ranson’s criteria were studied at the time of admission and after 48 hours. Result of these two were compared with that of revised Atlanta classification.Results: As per the BISAP score, the sensitivity and specificity were 95.8 % (95% CI, 76.8-99.8), 94.7 % (95% CI, 86.3-98.3) whereas positive likelihood ratio, negative likelihood ratio 18.21 (95% CI, 6.9-47.44), 0.04 (95% CI, 0.01-0.30) and accuracy was 95 % (95% CI, 88.72%-98.36%). On using Ranson’s score, the sensitivity and specificity were 91.6 (95% CI, 71.5-98.5) and 89.4 (95% CI, 79.8-95) with a positive predictive value 8.71 (95% CI, 4.47-18.96) and negative predictive value of 0.09 (95% CI, 0.02-0.35) and accuracy of 90% (95% CI, 82.38%-95.10%)..Conclusions: BISAP score outperformed Ranson’s score in terms of Sensitivity and specificity of prediction of severe pancreatitis. The authors recommend inclusion of BISAP Scoring system in standard treatment protocol of management of acute pancreatitis.
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2

V., Haridas T., and Asif Iqbal I. K. "A prospective study of the bedside index for severity in acute pancreatitis (BISAP) score in predicting severity and prognosis of acute pancreatitis." International Surgery Journal 6, no. 2 (January 28, 2019): 570. http://dx.doi.org/10.18203/2349-2902.isj20190405.

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Background: The aim of this study was to evaluate the ability of Bedside Index for Severity in Acute Pancreatitis (BISAP) score in predicting the severity and prognosis in patients admitted with acute pancreatitis.Methods: A prospective study was performed on 52 patients who presented with acute pancreatitis during the study period between January 2016 to November 2016. BISAP score was calculated for the patients. The disease was classified as mild or severe on the basis of presence of organ system failure and local/systemic complications. The accuracy of BISAP score in predicting the severity and prognosis of acute pancreatitis was evaluated.Results: Of the 52 patients studied, 11 patients had BISAP ≥2 and 41 patients had BISAP score <2. 9 of the 11 patients who had BISAP score ≥2 developed severe pancreatitis, local or systemic complications and had poor prognosis. 37 of the 41 patients who had BISAP score < 2 developed mild pancreatitis.Conclusions: BISAP score is accurate in predicting severity and prognosis of acute pancreatitis. Patients with BISAP score ≥2 developed severe pancreatitis and carried poor prognosis than patients with BISAP score <2.
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Karki, D., T. Tamang, D. Maharjan, P. Thapa, and S. Shrestha. "Comparison of BISAP score with Ranson’s score in predicting severe acute pancreatitis." Journal of Society of Surgeons of Nepal 18, no. 3 (July 25, 2016): 44. http://dx.doi.org/10.3126/jssn.v18i3.15306.

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Objectives: To compare BISAP score with Ranson’s scoring in predicting severity of acute pancreatitisMethods: Extensive demographic, radiographic, and laboratory data from consecutive patients with AP admitted to our institution was collected between March 2014 to March 2015. Ranson’s and BISAP score was calculated. Severity of pancreatitis was defined according to Atlanta classification. Sensitivity, Specificity, PPV, NPV of both the scoring system was calculated and compared.Results: A total of 42 patients with diagnosis of acute pancreatitis were included during the study period. 21(50%) were male and 21(50%) were female. Mean age is 49.52 ± 17.37.Most common etiology was biliary (45%) followed by alcohol (31%). 20 (48%) patients were categorized as severe pancreatitis according to Atlanta classification. 21 (50%) patients had a Ranson’s score of ≥3 and 19 (45.24%) patients had a BISAP score of ≥3. Both Ranson’s and BISAP scoring system was statistically significant in determining SAP ( p-value = 0.002). Sensitivity, specificity, PPV and NPV of Ranson’s and BISAP score was calculated to be 75%, 72.72%, 71.43%, 76.19% and 70%, 77.27%, 73.68%, 73.91%. respectively. The AUC for SAP by Ranson’s score is 0.7386 ; 95%CI (0.602 - 0.874) and BISAP score is 0.7364 ; 95% CI ( 0.599 - 0.872).Conclusions: Both Ranson’s and BISAP scoring system is similar in predicting SAP. However BISAP has the advantage due to its simplicity.
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Ansari, MArif, AmzadZia Mallik, Neelketu A, and Kundan Singh. "EVALUATION OF BISAP SCORING IN ACUTE PANCREATITIS." International Journal of Advanced Research 5, no. 6 (June 30, 2017): 2371–79. http://dx.doi.org/10.21474/ijar01/4682.

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5

Balasubramaniam, V. "Comparative study between BISAP score and Ranson score in predicting severity of acute pancreatitis." International Surgery Journal 8, no. 3 (February 25, 2021): 920. http://dx.doi.org/10.18203/2349-2902.isj20210518.

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Background: Acute pancreatitis has widely variable clinical and systemic manifestations spanning the spectrum from a mild, self-limiting episode of epigastric pain to severe, life-threatening, multi-organ failure. Since the morbidity and mortality of acute pancreatitis differ markedly between mild and severe disease (mild <5% versus severe 20–25%), it is very important to assess severity as early as possible. To assess the accuracy of the BISAP scoring system versus Ranson scoring system in predicting severity in an attack of acute pancreatitis.Methods: It is a prospective and retro prospective study that was conducted, from August 2018 to November 2019. All surgical units in the headquarters hospital, Ooty. BISAP score and Ranson’s score is calculated in all such patients based on data obtained within 48 hours of hospitalization.Results: Ranson’s score of more than 3 and the BISAP score of less than or equal to 3 had the best accuracy of predicting the severity of acute pancreatitis. Both Ranson’s score and BISAP score showed higher sensitivity in the prediction of systemic complications than that of local complications.Conclusions: From this study, we can conclude that the BISAP scoring system is not inferior to Ranson’s scoring system in predicting the severity of acute pancreatitis. BISAP scoring system is very simple, cheap, easy to remember and calculate. BISAP scoring system accurately predicts the outcome in patients with acute pancreatitis.
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Venkatapuram, Mahidhar Reddy, Sreeram Sateesh, and Deepthi Batchu. "A prospective study of BISAP score in assessing severity of acute pancreatitis." International Surgery Journal 5, no. 5 (April 21, 2018): 1785. http://dx.doi.org/10.18203/2349-2902.isj20181571.

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Background: Aim of study is to prospectively evaluate the ability of the Bedside Index for Severity in Acute Pancreatitis (BISAP) score to predict mortality as well as intermediate markers of severity.Methods: 50 patients admitted from December 2015 to November 2017 with acute pancreatitis were included in the study. BISAP score is calculated in all such patients based on data obtained within 24hrs of hospitalization. Patients were assessed for organ failure according to Marshall scoring system and followed throughout hospitalization for assessment of complications. Statistical analyses were made using Fischer’s exact probability test. The difference was assumed statistically significant when p<0.05.Results: There was a statistically highly significant trend for increasing mortality (p < 0.05) and intermediate markers of severity (p<0.05) that is transient organ failure, persistent organ failure and pancreatic necrosis with BISAP score ≥3.Conclusions: The BISAP score represents a simple way to identify patients at risk of increased mortality and the development of intermediate markers of severity within 24 hours of presentation.
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7

Bung, Yogesh Kumar, Chandrasekhar Sharanappa Neeralagi, Lakkanna Suggaiah, Usharani Rathnam, and Chandrakant Kesari. "A prospective study to predict the severity of acute pancreatitis by BISAP score." International Surgery Journal 4, no. 7 (June 22, 2017): 2221. http://dx.doi.org/10.18203/2349-2902.isj20172770.

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Background: Acute pancreatitis (AP) is as an inflammation of the pancreas with varied range of complication like peri-pancreatic collection, pancreatic necrosis, renal failure, multi-organ dysfunction syndrome which increases mortality rate and morbidity. Majority of AP cases are mild but severe cases of AP are associated with increased complication and mortality. BISAP is simple bedside prognostic scoring system for predicting severity of AP. BISAP is a collection of simple routine investigation and scores are quantified at 24hours of onset of AP. This study aims to assess prognosis of AP cases at ESIC Medical college and Post Graduate Institute of Medical Science and Research, Bangalore, Karnataka, India.Methods: A prospective study of 60 Patients who were diagnosed as AP according to RAC. All patients were admitted in high dependency unit with close observation of vital parameters and investigations were done at 24 hours of onset of AP. BISAP score >3 was considered as Severe Acute Pancreatitis, its correlation with local complications, organ failure, ICU stay and Mortality was studied. Statistical analysis done using Chi-square test and Fisher Exact test for local complications and organ failure using xL Stat and SPSS v.21.0, a p-value <0.05 was considered to be significant.Results: Of the 60 patients, BISAP score was >3 and <3 in 15 and 45 patients respectively. Alcohol was the most common cause of acute pancreatitis, accounting for 53.33%. In current study 12 (20%) patients developed organ failure and among them 9 (75%) had transient organ failure and 3 (25%) had persistent organ failure. Total 8 (13%) patients had developed pancreatic necrosis and among them 6 had BISAP >3. Mortality rate in this study was 2%.Conclusions: The BISAP score is a simple and fairly accurate method for the early identification of patients at increased risk for in hospital mortality and to identify patients at risk of the development of intermediate markers of severity and organ failure within 24 hours of presentation.
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Ghunage, Aditya Vasant, and Kiran Shrikant Kher. "Assessment of BISAP Scoring System and C-Reactive Protein Analysis in Predicting Severity of Acute Pancreatitis." Journal of Evolution of Medical and Dental Sciences 10, no. 35 (August 30, 2021): 2985–88. http://dx.doi.org/10.14260/jemds/2021/610.

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BACKGROUND Acute pancreatitis (AP) is a dormant deadly illness. The range of seriousness of the ailment goes from mellow self-restricting disease to an exceptionally lethal severe necrotizing pancreatitis. The disease has such a variable course that it may manifest as a simple pain in the abdomen to severe haemorrhagic pancreatitis with septicaemic shock, multi-organ dysfunction syndrome and ultimately leading to death. A cost-effective better prognosticative index is needed for the assessment of the severity of AP. Here in this study, we wanted to assess the role of BISAP scoring systems and CRP for analysis and comparing their values to determine the severity of AP and the prognosis of the disease. METHODS A prospective observational study was done on 83 patients diagnosed with AP after fulfilment of inclusion criteria. Patients were subjected to severity index, bedside index for severity in acute pancreatitis (BISAP) score and CRP calculation and statistical analysis was done with SPSS software. RESULTS In our study, AP was more prevalent in males 87.95 % than females 12.05 %. AP was found to be more common in cases ≤ 40 years of age, however, the mean age of presentation was 38.14 ± 12.59 years. We calculated the sensitivity and specificity of the BISAP score and C-reactive protein (CRP) by co-relating it with CT severity index as gold standard according to which the sensitivity was found to be 64 % and specificity was found to be 85 % for BISAP. The sensitivity and specificity of CRP was 64 % and 85 % respectively. CONCLUSIONS BISAP is an easy way to anticipate the severity of AP within 24 hours. It also helps to prognosticate AP. CRP can also be used to aid BISAP in the assessment of severe acute pancreatitis (SAP). KEY WORDS Acute Pancreatitis, BISAP, CRP.
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9

Kuntoji, Shrikant B., and Shaik Karimulla. "Efficacy of BISAP score versus Ranson’s score to determine the severity index of acute pancreatitis." International Surgery Journal 8, no. 6 (May 28, 2021): 1826. http://dx.doi.org/10.18203/2349-2902.isj20212279.

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Background: Acute pancreatitis has widely variable clinical and systemic manifestations spanning the spectrum from a mild, self-limiting episode of epigastric pain to severe, life-threatening, multiorgan failure posing a significant therapeutic challenge for the health care providers. Bedside index of severity in acute pancreatitis (BISAP) is a scoring system that would precisely predict severity as early as within the first 24 hours of the course of acute pancreatitis. This study aims to compare BISAP and Ranson’s score to establish the validity of a simple and accurate clinical scoring system for stratifying patients.Methods: All 84 cases admitted at HSK Hospital and SNMC, Bagalkot and diagnosed as acute pancreatitis were included in this study, from January 2019 to June 2020. Clinical evaluation in the form of detailed history, per abdominal, systemic examination and laboratory investigations, both BISAP and Ranson’s score were applied and compared, based upon data obtained at admission, within 24 hours and at 48 hours of hospitalization.Results: Out of 84 cases with a male to female ratio of 16:1, majority belonged to age group 31-40 years (42%) and most common etiological factor being alcohol consumption (74%); 19% patients had severe acute pancreatitis and 68% patients had length of hospital stay less than a week. Major organ failure and pancreatic necrosis, severity of BISAP and Ranson’s score were found to be significantly correlated, (p<0.001); mortality was found to be 1.2%.Conclusions: Compared to Ranson’s score, BISAP score is equally effective in finding out the frequency of severity and predicting mortality in patients with acute pancreatitis .The values in BISAP score are instantaneous with no time delay.
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10

M. R., Kaushik, A. P. Dubey, Rahul Jain, Anvesh Rathore, and Abhishek Pathak. "Prospective evaluation of the BISAP score and its correlation with Marshall score in predicting severity of organ failure in acute pancreatitis." International Journal of Advances in Medicine 4, no. 2 (March 23, 2017): 534. http://dx.doi.org/10.18203/2349-3933.ijam20171056.

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Background: The bedside index for severity in acute pancreatitis (BISAP), a newer prognostic scoring system, has been proposed as a simple and clinically oriented severity scoring system for early identification of patients with acute pancreatitis. This study evaluates the efficacy of BISAP score to predict the severity of organ failure in patients of acute pancretitis and its correlation with Marshall score.Methods: The clinical, laboratory and radiological data for all patients admitted with a diagnosis of acute pancreatitis conducted at tertiary hospital of Armed Forces over a two-year period, was prospectively collected for this study. BISAP score was calculated within 24hrs of presentation. Markers of severity were the development of organ failure and presence of pancreatic necrosis. Outcome at 28 days (viz. recovery, organ failure and mortality) was studied for each patient. BISAP score computed at 24h was correlated with the above and its efficacy to predict the severity of organ failure in Acute Pancreatitis, was assessed.Results: Out of 50 patients in the study group, 41 were male and 9 were female with the mean (±SD) age 43.74±16.85 years. Majority of the study population had alcohol (56%) as the etiology followed by gall stones (28%). Outcome assessed at 28 days revealed recovery of 54%, complication of 36% and mortality of 10% of study population. BISAP score computed within 24 hours of admission of 2 or more significantly predicted the severity and complication with P value <0.001. Statistically significant trends of increasing severity and organ failure (P<0.001) with increasing BISAP was observed.Conclusions: BISAP score is a reliable means of predicting the severity and organ failure and stratifying patients with Acute Pancreatitis within 24 hours of admission. The statistically significant incidence of increasing severity and mortality with increasing BISAP score will help us to risk stratify the patients within 24 hours of admission and help improve clinical care and facilitate necessary interventions as early as possible.
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11

Karki, Sanjit, Binod Karki, Suresh Thapa, Roshan Shrestha, Bidhan Nidhi Poudel, and Ramila Shrestha. "Accuracy of bedside index for severity in acute pancreatitis ‘BISAP’ score in predicting outcome of acute pancreatitis." Journal of Patan Academy of Health Sciences 7, no. 2 (August 30, 2020): 70–76. http://dx.doi.org/10.3126/jpahs.v7i2.31117.

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Introduction: Early identification of severe acute pancreatitis is of paramount importance in the management and for improving outcomes. Bedside index for severity in acute pancreatitis (BISAP) is a simple and accurate score for stratification in acute pancreatitis. This study was conducted to find out the accuracy of BISAP score in predicting outcomes of acute pancreatitis in local population. Method: We prospectively analyzed 96 patients with acute pancreatitis from February 2019 to December 2019. Revised Atlanta classification was used to stratify mild, moderately severe and severe pancreatitis. BISAP score was calculated within 24 hours of admission. Accuracy was measured by area under receiver operating curve (AUC). Result: Out of 96 patients, alcohol related acute pancreatitis accounted for 74.7%. There were 63.2% of mild AP, 37.3% of moderately severe AP, 9.4% of severe AP and 15.8 % of pancreatic necrosis. The AUC for moderately severe AP, severe AP and pancreatic necrosis were 0.77 (CI 0.68-0.87), 0.95 (CI 0.90-0.99) and 0.87 (CI 0.79-0.96) respectively. The statistically significant BISAP cut off for diagnosing sever AP was≥3, and ≥2 for moderately sever AP and pancreatic necrosis. There was positive correlation between revised Atlanta severity of acute pancreatitis and length of hospital stay (r=0.41). Mortality was 3.3 % which was seen in BISAP score 3 or above. Conclusion: BISAP is a simple predictive model in identifying patient at a risk of developing different severity of pancreatitis and its outcome in our population.
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Chen, Lifen, Guomin Lu, Qunyan Zhou, and Qiang Zhan. "Evaluation of the BISAP Score in Predicting Severity and Prognoses of Acute Pancreatitis in Chinese Patients." International Surgery 98, no. 1 (February 1, 2013): 6–12. http://dx.doi.org/10.9738/0020-8868-98.1.6.

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Abstract The present study was to evaluate the accuracy of bedside index for severity in acute pancreatitis (BISAP) in predicting the severity and prognoses of acute pancreatitis (AP) in Chinese patients. Clinical data for 497 patients with AP were analyzed retrospectively to compare BISAP with acute physiology and chronic health evaluation II, Ranson, and computed tomography severity index scores in predicting the severity of AP and the occurrence of pancreatic necrosis, mortality, and organ failure in patients with severe AP (SAP) using the area under the receiver-operating characteristic curve. Of the 497 patients, 396 had mild AP and 101 had SAP. There were significant correlations between the scores of any two systems. BISAP performed similarly to other scoring systems in predicting SAP, as well as pancreatic necrosis, mortality, and organ failure in SAP patients, in terms of the area under the receiver-operating characteristic curve. BISAP score is valuable in predicting the severity of AP and prognoses of SAP in Chinese patients.
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P, Raga, and Rup K. "A Prospective study of BISAP score in Acute Pancreatitis." Narayana Medical Journal 9, no. 2 (2020): 9. http://dx.doi.org/10.5455/nmj/00000187.

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Singhvi, Gaurav, Raghav Bansal, Ishita Rajnish, Melik Tiba, Loveleen Sidhu, Umer M. Syed, Aaron Walfish, Vishal Ghevariya, and Ilnaz Salehi. "Predicting the Severity of Gallstone Pancreatitis Using BISAP Score." American Journal of Gastroenterology 110 (October 2015): S40. http://dx.doi.org/10.14309/00000434-201510001-00097.

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15

Karpavičius, Andrius, Žilvinas Dambrauskas, Artūras Samuilis, Audrius Gradauskas, Kristina Žvinienė, Gintautas Brimas, Jonas Činčikas, Artur Mečkovski, Audrius Šileikis, and Kęstutis Strupas. "KLINIKINIŲ IR RADIOLOGINIŲ SKALIŲ VERTĖ PROGNOZUOJANT ŪMINIO PANKREATITO EIGĄ IR KOMPLIKACIJAS. PERSPEKTYVINIO DAUGIACENTRIO KOHORTINIO TYRIMO REZULTATAI." Medicinos teorija ir praktika 21, no. 4.3 (December 10, 2015): 814–21. http://dx.doi.org/10.15591/mtp.2015.129.

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Reikšminiai žodžiai: pankreatitas, prognozavimas, BISAP, CTSI, MCTSI. Darbo tikslas. Įvertinti klinikinių bei radiologinių skalių vertę, prognozuojant ŪP eigą, kasos nekrozę, intervencijų poreikį ir išeitis. Medžiaga ir metodai. Multicentrinė perspektyvinė studija buvo vykdoma keturiose Vilniaus ir Kauno gydymo įstaigose. Hospitalizuotų dėl ūminio pankreatito pacientų būklė 1-ąją hospitalizacijos parą įvertinta naudojant HAPS ir BISAP prognozines skales, apskaičiuojant surinktus balus. 3–7-ą susirgimo parą pacientams buvo atliekama pilvo organų kompiuterinė tomografija su intaveniniu kontrastavimu ir apskaičiuoti CTSI ir MCTSI skalių balai. Remiantis atnaujintu Atlantos sutarimu, visi pacientai buvo suskirstyti į tris grupes pagal ligos eigą: lengvo, vidutinio sunkumo ir sunkaus ūminio pankreatito. Klinikinių ir radiologinių skalių balai buvo lyginami tarp grupių, ir, braižant ROC kreives, nustatytos kritinės reikšmės, kuriomis remiantis galima prognozuoti sunkios eigos ūminį pankreatitą, kasos nekrozę, intervencijas bei išeitis. Rezultatai. Tyrime dalyvavo 102 ūminiu pankreatitu sirgę pacientai. Iš jų lengvu ūminiu pankreatitu sirgo 27 (26,5%), vidutinio sunkumo – 55 (53,9%) ir sunkiu – 20 (19,6%) asmenų. Nustatyta, jog BISAP (kritinė reikšmė ≥2), CTSI (kritinė reikšmė ≥6) bei MCTSI (kritinė reikšmė ≥8) skalės statistiškai patikimai atskiria sunkiu ūminiu pankreatitu sergančius pacientus nuo sergančių lengvesnėmis formomis. Kasos nekrozės kritinės prognozinės reikšmės yra ≥2 (BISAP), ≥3 (CTSI) ir ≥5 (MCTSI) balai. BISAP skalės kritinė prognozinė vertė intervencijoms yra ≥3 balai, CTSI – ≥5, o MCTSI – ≥8 balai; paciento mirtį atitinkamai prognozuoja – ≥4, ≥6 ir ≥8 balai. Išvados. BISAP prognozinė sistema yra gana tiksli, universali ir ankstyva prognozuojant SŪP, kasos nekrozę, intervencijas bei išeitis. Radiologinės skalės tinkamos ŪP eigai prognozuoti, tačiau yra per daug vėlyvos ir labiau naudingos gydymo taktikai parinkti.
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Bezmarevic, Mihailo, Zoran Kostic, Miodrag Jovanovic, Sasa Mickovic, Darko Mirkovic, Ivan Soldatovic, Bratislav Trifunovic, Janko Pejovic, and Svetlana Vujanic. "Procalcitonin and BISAP score versus c-reactive protein and APACHE II score in early assessment of severity and outcome of acute pancreatitis." Vojnosanitetski pregled 69, no. 5 (2012): 425–31. http://dx.doi.org/10.2298/vsp1205425b.

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Background/Aim. Early assessment of severity and continuous monitoring of patients are the key factors for adequate treatment of acute pancreatitis (AP). The aim of this study was to determine the value of procalcitonin (PCT) and Bedside Index for Severity in Acute Pancreatitis (BISAP) scoring system as prognostic markers in early stages of AP with comparison to other established indicators such as Creactive protein (CRP) and Acute Physiology and Chronic Health Evaluation (APACHE) II score. Methods. This prospective study included 51 patients (29 with severe AP). In the first 24 h of admission in all patients the APACHE II score and BISAP score, CRP and PCT serum concentrations were determined. The values of PCT serum concentrations and BISAP score were compared with values of CRP serum concentrations and APACHE II score, in relation to the severity and outcome of the disease. Results. Values of PCT, CRP, BISAP score and APACHE II score, measured at 24 h of admission, were significantly elevated in patients with severe form of the disease. In predicting severity of AP at 24 h of admission, sensitivity and specificity of the BISAP score were 74% and 59%, respectively, APACHE II score 89% and 69%, respectively, CRP 75% and 86%, respectively, and PCT 86% and 63%, respectively. It was found that PCT is highly significant predictor of the disease outcome (p < 0,001). Conclusion. In early assessment of AP severity, PCT has better predictive value than CRP, and similar to the APACHE II score. APACHE II score is a stronger predictor of the disease severity than BISAP score. PCT is a good predictor of AP outcome.
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Jácome Morejón, Pablo Andres, and Diego Andrés Berrezueta Córdova. "Escala BISAP en pancreatitis aguda. Azogues 2016-2017. Estudio descriptivo." Revista de la Facultad de Ciencias Médicas de la Universidad de Cuenca 37, no. 2 (October 2, 2019): 21–29. http://dx.doi.org/10.18537/rfcm.37.02.03.

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Kantly, Ramalingeshwara, and Nataraj Naidu R. "BISAP: A NOVEL METHOD FOR ASSESSING SEVERITY OF ACUTE PANCREATITIS." Journal of Evolution of Medical and Dental Sciences 3, no. 42 (September 5, 2014): 10428–34. http://dx.doi.org/10.14260/jemds/2014/3357.

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Sarfraz Janjua, Saad, Fakhar Zaman, and Tehmina Qamar. "Comparison of Ranson’s Score, BISAP, and CTSI in Predicting the Severity of Acute Pancreatitis." Journal of Islamabad Medical & Dental College 7, no. 4 (January 2, 2019): 255–59. http://dx.doi.org/10.35787/jimdc.v7i4.256.

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Objective: To use of Ranson’s, BISAP and CTSI scoring system in predicting the severity and outcomes of patients with acute pancreatitis.Patients and Methods: One hundred and six (106) patients of acute pancreatitis were studied prospectively. Data of patient’s baseline demographics, clinical and radiological investigation was collected. BISAP score was calculated by obtaining data within 24 hours of admission, while Ranson score was calculated at the time of admission and at 48 hours of admission. CTSI was based on findings from CT scan of selected patients. Severity of acute pancreatitis was defined in terms of ICU admission, development of associated complications and mortality.ResultsOut of 106 patients, 55.7% were females and 44.3% were male patients. Regarding complications of Acute Pancreatitis, 9 (8.5%) patients were admitted in ICU, complications occurred in 33 (31.1%) patients while mortality occurred in 9 (8.5%) patients. Out of 106 patients 11 patients had Ransons score greater than 3. 04(36.4%) patients required ICU admission, 07(63.6%) patients developed complications and mortality of 5(45.5%) patients occurred. Patients with Bisap score greater 03, 6 (26%) patients required ICU admission, 17 (74%) developed complications and mortality of 8(34.7%) patients occurred. 24 patients underwent CECT abdomen and 4 patients had modified CTSI score of 8 to 10 (severe AP) out of which 4(100%) patients required ICU admission, 4(100%) patients developed complications and mortality occurred in 4(100%) patients. Conclusion: BISAP score is a useful prognostic scoring system for predicting the severity of acute pancreatitis and can be a crucial aid in determining the group of patients that have a high chance of need for intensive care during the course of their illness and therefore need early resuscitation; especially in resource-limited developing countries.
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Kantly, Ramalingeshara, and Abhijit Medikeri. "Study on severity assessment of acute pancreatitis using BISAP score in rural area of south India." International Surgery Journal 5, no. 8 (July 24, 2018): 2777. http://dx.doi.org/10.18203/2349-2902.isj20182997.

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Background: Acute Pancreatitis is one of the most common disease in all parts of INDIA. The morbidity and mortality of the disease can be reduced by early detection of complications. In rural health centres, authors need a simple and easily accessible and reproducible scoring system to access the severity. The main aim of the study is, using BISAP score authors can easily identify the severity and complications of acute pancreatitis as early as possible even in rural health centres.Methods: This is a prospective study conducted at Koppal District Hospital, Karnataka. Authors included 80 acute pancreatitis patients admitted in present hospital from July 2015 to July 2017. BISAP score is used within 24 hours of admission to access the severity and complications of the pancreatitis. Complications are accessed with respect to duration of hospital stay, organ failure and necrotising pancreatitis against BISAP score less than 3 and more than 3.Results: In present study male (83.75%) patients are more affected than females (16.25%). Alcohol (52.5%) being the main culprit then biliary (32.5%) and idiopathic (15%) as causes of acute pancreatitis. Middle age group between 30 to 50 years (66.25%) are more affected. Severe pancreatitis features like organ failure (66.67%) and necrotising pancreatitis (71.4%) are seen in patients with score more than 3. And also, the duration of inpatient hospital stay is longer (more than 5 day) in same patients.Conclusions: Acute pancreatitis is one of the most common causes for acute abdomen and alcohol consumption being the main culprit in rural areas of south India. Of the many scoring systems, BISAP score can be easily done at rural health centres to early detection of severity and complication of acute pancreatitis.
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Venkateswaran, Ramalakshmi, Kannan Ross, Sarayu S, Kenny Robert, and Kadhirvel S. "PROSPECTIVE EVALUATION OF BISAP SCORING IN ASSESSING SEVERITY IN ACUTE PANCREATITIS." Journal of Evidence Based Medicine and Healthcare 3, no. 100 (December 14, 2016): 5511–16. http://dx.doi.org/10.18410/jebmh/2016/1141.

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Pattanaik, S. K., V. Arvind Kumar, and Ajax John. "Comparison of bedside index of severity in acute pancreatitis (BISAP) and acute physiology and chronic health evaluation (APACHE II) score in assessing severity of acute pancreatitis." International Surgery Journal 4, no. 12 (November 25, 2017): 4054. http://dx.doi.org/10.18203/2349-2902.isj20175409.

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Background: Acute Pancreatitis (AP) is one among the major diseases in the surgery wards with high rate of mortality. In spite of many scoring systems introduced to grade the severity of AP for optimal and timely management, mortality rate is still in a high pace. The aim of this study is to compare BISAP scoring system and APACHE II scoring system for accuracy and easiness in predicting the severity and mortality of AP and to deliver appropriate and timely intervention.Methods: The first 100 patients with AP in the year 2016 (January to August) were studied prospectively by calculating APACHE II score and BISAP score. According to Revised Atlanta classification severe AP was ascertained and the sensitivity and specificity of both scoring systems were assessed from chi square table. By using ROC curve accuracy and diagnostic value of two scoring systems were compared.Results: 100 patients with an age ranging from 20 to 80 years with a mean of 41.18 and male female ratio of 10.1:1 were studied. 95% of the patients presented with a symptom of abdominal pain and 49 out of 100 were having alcoholism as etiology. The average hospital stay of the patients was 12.03 days. Four patients died out of 11 severe AP and rest 89 were grouped into mild AP. BISAP score more than or equal to three have 64.2% chance of severe AP and was statistically significant in predicting the severity of AP. Areas under curve of the ROC curve after depicting the sensitivity and specificity of BISAP scores for severity and mortality were 0.90 and 0.96 respectively. APACHE II scores more than or equal to nine have 23.8% chance of severe AP and was statistically significant in predicting severity of AP. When sensitivity and specificity of APACHE II score were charted in ROC curve, areas under curve were 0.853 and 0.75 for severity and mortality in AP respectively.Conclusions: Compared to APACE II, BISAP is better scoring system in predicting both severity and mortality of AP on considering accuracy and easiness.
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Sehgal, Rishabh, Inder Pal Singh, and Jyotisterna Mittal. "Clinical Profile and Outcome of Patients with Severe Acute Pancreatitis." Asian Journal of Medical Research 9, no. 3 (October 6, 2020): 8–11. http://dx.doi.org/10.47009/ajmr.2020.9.3.me2.

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Background: Acute pancreatitis (AP) is an acute inflammatory condition of the pancreas leading to pancreatic autodigestion. The present study was conducted to study the clinical profile and outcome of patients with severe acute pancreatitis. Subjects & Methods: The study was conducted on 40 patients of acute pancreatitis. Clinical profile including history, examination findings, etiology of pancreatitis, clinical severity (according to Modified Marshall Score, BISAP score, APACHE II, HAPS score, SOFA score) was recorded. Results: Severe Acute Pancreatitis (SAP) among patients. Majority of the patients i.e. 22 (55%) had alcohol consumption as etiological factor causing SAP followed by biliary 10 (25%) & idiopathic 5 (12.5%). Hypertriglyceridemia and drug-induced (herbal medication) pancreatitis was present in 1 (2.5%) patient each. Out of all 1 (2.5%), patients had a history of both alcohol consumption and the presence of gallstone as an etiological factor. 22 patients (55%) out of 40 patients only conservative management was used while 18(45%) patients underwent USG guided percutaneous drainage was done. Out of these 18 patients, 3(7.5%) patients required Laparoscopic Necrosectomy & 2(5%) patients required open necrosectomy in addition to ultrasound-guided PCD. Patients who improved had a mean BISAP SCORE of 2.15 0.54, Modified Marshall score of 3.65 1.44, APACHE II score of 9.77 4.45, SOFA score 5.54 2.49, RANSON’s score 3.85 1.80 and HAP score of 0.65 0.63. Conclusion: Most common etiology of severe acute pancreatitis is alcohol followed by biliary etiology. Out of severity scores (BISAP, APACHE-II, SOFA, HAPS), only BISAP score ≥3 is predictive of poor outcome in patients with severe acute pancreatitis.
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Machindra, Gaikwad Avinash, and Rajeshwara K.V. "Study of BISAP Scoring System, Ranson’s Scoring System and C-Reactive Protein Level as Predictors of Clinical Outcome in Acute Pancreatitis." Journal of Evolution of Medical and Dental Sciences 10, no. 11 (March 15, 2021): 784–88. http://dx.doi.org/10.14260/jemds/2021/168.

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BACKGROUND This study was conducted to compare BISAP scoring system, Ranson’s score and CRP levels in predicting the clinical outcome in acute pancreatitis and for early detection of severity and organ failure in acute pancreatitis. METHODS This study was an observational longitudinal analytical study conducted among patients admitted with diagnosis of acute pancreatitis, in Father Muller Medical College Hospital, Mangalore, from November 2016 to March 2018. The study was started after obtaining ethical clearance from the institution’s ethical clearance committee. All patients diagnosed with acute pancreatitis between the age 20 and 60 years were included in the study. RESULTS Comparison of serum CRP levels between the Atlanta classified groups shows that severe group has the maximum value of 340.966 and mild has the minimum value of 55.38. This difference is statistically significant with a test value of 16.543 and a P value of < 0.001. On comparison of the test group, Ranson’s score with the BISAP score, the test group had a sensitivity of 89.3 % and specificity of 77.3 %. CONCLUSIONS The study has demonstrated the concordance between Ranson’s score, BISAP score and serum CRP level as predictors of clinical outcome in acute pancreatitis. KEY WORDS Acute Pancreatitis, Clinical Outcome, C Reactive Protein, Scoring Systems.
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Gezer, Naciye S., Göksel Bengi, Agah Baran, Pakize E. Erkmen, Ömer S. Topalak, Canan Altay, and Oğuz Dicle. "Comparison of radiological scoring systems, clinical scores, neutrophil-lymphocyte ratio and serum C-reactive protein level for severity and mortality in acute pancreatitis." Revista da Associação Médica Brasileira 66, no. 6 (June 2020): 762–70. http://dx.doi.org/10.1590/1806-9282.66.6.762.

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SUMMARY Comparison of radiological scoring systems, clinical scores, neutrophil-lymphocyte ratio and serum C-reactive protein level for severity and mortality in acute pancreatitis BACKGROUND/AIMS To compare radiological scoring systems, clinical scores, serum C-reactive protein (CRP) levels and the neutrophil-lymphocyte ratio (NLR) for predicting the severity and mortality of acute pancreatitis (AP). MATERIALS AND METHODS Demographic, clinical, and radiographic data from 80 patients with AP were retrospectively evaluated. The harmless acute pancreatitis score (HAPS), systemic inflammatory response syndrome (SIRS), bedside index for severity in acute pancreatitis (BISAP), Ranson score, Balthazar score, modified computed tomography severity index (CTSI), extrapancreatic inflammation on computed tomography (EPIC) score and renal rim grade were recorded. The prognostic performance of radiological and clinical scoring systems, NLR at admission, and serum CRP levels at 48 hours were compared for severity and mortality according to the revised Atlanta Criteria. The data were evaluated by calculating the receiver operator characteristic (ROC) curves and area under the ROC (AUROC). RESULTS Out of 80 patients, 19 (23.8%) had severe AP, and 9 (11.3%) died. The AUROC for the BISAP score was 0.836 (95%CI: 0.735-0.937), with the highest value for severity. With a cut-off of BISAP ≥2, sensitivity and specificity were 68.4% and 78.7%, respectively. The AUROC for NLR was 0.915 (95%CI: 0.790-1), with the highest value for mortality. With a cut-off of NLR >11.91, sensitivity and specificity were 76.5% and 94.1%, respectively. Of all the radiological scoring systems, the EPIC score had the highest AUROC, i.e., 0.773 (95%CI: 0.645-0.900) for severity and 0.851 (95%CI: 0.718-0.983) for mortality, with a cut-off value ≥6. CONCLUSION The BISAP score and NLR might be preferred as early determinants of severity and mortality in AP. The EPIC score might be suggested from the current radiological scoring systems.
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Edakkepuram, Unnikrishnan, Muhammad Navas N. K., Sasi M. Parambil, and Siddharth Matad. "Total serum calcium and corrected calcium as severity predictors in acute pancreatitis: a prospective study in a tertiary hospital in South India." International Surgery Journal 4, no. 2 (January 25, 2017): 560. http://dx.doi.org/10.18203/2349-2902.isj20164848.

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Background: Acute pancreatitis still remains a disease of growing burden to mankind; it is an unpredictable, potentially lethal disease with a high mortality. The incidence of acute Pancreatitis appears to be increasing. Aim of the study was to evaluate total serum calcium and corrected calcium as prognostic severity factors in acute pancreatitis.Methods: This prospective study was conducted in a tertiary hospital from July2015 to June 2016. All the patients who were diagnosed to have acute pancreatitis by clinical examination, laboratory, radiological and biochemical investigations were considered as cases. Serum calcium and albumin corrected calcium measured within 24 hours of admission. Patients followed up for a maximum period of 4 weeks and outcome studied, in terms of whether patient had local or systemic complication, mortality. Significance of serum calcium and albumin corrected calcium in predicting outcome of acute pancreatitis is assessed and compared with BISAP score.Results: Acute pancreatitis most commonly occurs in the age group of 30-50. 80% of acute pancreatitis occurs in male and 20% in female. Alcoholism accounts for 58% cases of acute pancreatitis and gall stone account for 28% of acute pancreatitis.Conclusions: Hypocalcaemia and low ACC can predict severity of acute pancreatitis, as with BISAP score, but it is not superior to BISAP score.
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Duraisami, Vinodh, Gunasekaran Balraj, and Vinyak Rengan. "Comprehensive analysis of etiology, prognosis and clinical outcome of acute pancreatitis in a tertiary care center." International Surgery Journal 5, no. 12 (November 28, 2018): 3947. http://dx.doi.org/10.18203/2349-2902.isj20185024.

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Background: Acute pancreatitis can be classified as mild and severe. Mild pancreatitis is explained by interstitial edema of the gland and it is usually a self-limiting form. Whereas in severe pancreatitis, there is pancreatic necrosis, severe systemic inflammatory response and multi-organ failure which may lead to mortality. To identify the most common etiological agent of acute pancreatitis in our institution.Methods: Patients diagnosed with acute pancreatitis in Institute of General Surgery, Rajiv Gandhi Govt. General Hospital. 50 of them are to be selected on the basis of nonprobability (purposive) sampling method. Data pertinent to the scoring systems will be recorded within 24 h of admission to the hospital.Results: 86% of patients had BISAP score less than 3 (mild) and 14% of patients had more or more than 3 (severe). The cases with mild, moderate and severe CTSI score were 76%, 20% and 4% respectively. Only two cases with BISAP score 3 or more had CTSI >6.Conclusions: Alcohol is the most common etiological factor for acute pancreatitis in this regional population. The morbidity rate is 26% and the mortality rate in patients with severe pancreatitis was 4%. The BISAP score is more accurate in predicting disease severity and significantly than CTSI in this study.
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Santos, Patricia, Samuel Fernandes, Miguel Moura, Joana Carvalho, Teresa Antunes, and José Velosa. "Evaluation of the BISAP score in predicting severity and prognosis of acute pancreatitis." Pancreatology 15, no. 3 (June 2015): S63—S64. http://dx.doi.org/10.1016/j.pan.2015.05.244.

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Bhatt, Amit, Jordan Holmes, Rocio Lopez, Maged Rizk, and Tyler Stevens. "Elevated BISAP Score Is Associated with Early Unplanned Readmission in Acute Pancreatitis (AP)." American Journal of Gastroenterology 106 (October 2011): S60. http://dx.doi.org/10.14309/00000434-201110002-00149.

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TG, Dinesh Krishna, Sidduraj C. Sajjan, and Bijaya Kumar Sethi. "Comparative Study Between BISAP Scoring System and C-Reactive Protein Analysis in Predicting Severity of Acute Pancreatitis." New Indian Journal of Surgery 11, no. 1 (2020): 23–34. http://dx.doi.org/10.21088/nijs.0976.4747.11120.3.

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JAIN, Deepak, Gourab BHADURI, and Promil JAIN. "DIFFERENT SCORING SYSTEMS IN ACUTE ALCOHOLIC PANCREATITIS: WHICH ONE TO FOLLOW? AN ONGOING DILEMA." Arquivos de Gastroenterologia 56, no. 3 (September 2019): 280–85. http://dx.doi.org/10.1590/s0004-2803.201900000-53.

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ABSTRACT BACKGROUND: Acute pancreatitis is a common disorder in medical practice. In recent times, management has changed drastically with majority of decisions like intravenous antibiotics, negative suction with Ryle’s tube and surgical interventions like necrosectomy etc based on severity of the disease. There are different scores in use to assess severity of disease but the relative efficacy has remained a debatable subject. OBJECTIVE: The present study was thus done to investigate the predictive accuracy of different scoring systems in acute pancreatitis. METHODS: Fifty patients of acute pancreatitis admitted in medicine ward of Pt. B.D. Sharma PGIMS, Rohtak, India, were taken for study after fulfilling eligibility criteria. These patients were investigated at admission and followed up prospectively. The severity of pancreatitis was classified for each of these patients as per Revised Atlanta System of Classification. Commonly used scoring systems pertaining to acute pancreatitis, viz, BISAP, Ranson, APACHE II and modified computed tomography severity index (CTSI) were calculated. Subsequently these scores were then correlated with severity, presence of organ failure, occurrence of local complications and final outcome of the patients. RESULTS: Out of 50 patients, etiology was chronic alcohol intake in all but one with idiopathic pancreatitis. The mean age of the study population was 42.06±13.27 years. 32% of these patients had pancreatic necrosis, 40% had peripancreatic collections. 56% of them had mild acute pancreatitis, 24% had moderately severe acute pancreatitis, while 20% had severe acute pancreatitis. APACHE II had the highest accuracy in predicting severity, organ failure and fatal outcomes. As far as these parameters were concerned, the negative predictive values of BISAP score were also considerable. Modified CTSI score was accurate in predicting local complications but had limited accuracy in other predictions. CONCLUSION: APACHE II emerged as most reliable scoring system followed by BISAP and Ranson in management of the patients with acute pancreatitis. But in constraints of time and resources, even BISAP score with its significant negative predictive values served as a valuable tool for assessing and managing these patients.
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Yang, Lixin, Jing Liu, Yun Xing, Lichuan Du, Jing Chen, Xin Liu, and Jianyu Hao. "Comparison of BISAP, Ranson, MCTSI, and APACHE II in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients." Gastroenterology Research and Practice 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/1834256.

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In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP). We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 diagnosed hyperlipidemic acute pancreatitis patients from August 2006 to July 2015 were studied retrospectively. Our result showed that all four scoring systems can be used to predict the severity, local complications, and mortality of HLAP. Ranson did not have significant advantage in predicting severity and prognosis of HLAP compared to other three scoring systems. APACHE II was the best in predicting severity of HLAP, but it had shortcoming in predicting local complications. MCTSI had outstanding performance in predicting local complications, but it was poor in predicting severity and mortality. BISAP score had high accuracy in assessment of severity, local complications, and mortality of HLAP, but the accuracy still needs to be improved in the future.
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Pando, Elizabeth, Piero Alberti, Rodrigo Mata, María José Gomez, Laura Vidal, Arturo Cirera, Cristina Dopazo, et al. "Early Changes in Blood Urea Nitrogen (BUN) Can Predict Mortality in Acute Pancreatitis: Comparative Study between BISAP Score, APACHE-II, and Other Laboratory Markers—A Prospective Observational Study." Canadian Journal of Gastroenterology and Hepatology 2021 (March 22, 2021): 1–8. http://dx.doi.org/10.1155/2021/6643595.

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Background. Changes in BUN have been proposed as a risk factor for complications in acute pancreatitis (AP). Our study aimed to compare changes in BUN versus the Bedside Index for Severity in Acute Pancreatitis (BISAP) score and the Acute Physiology and Chronic Health Evaluation-II score (APACHE-II), as well as other laboratory tests such as haematocrit and its variations over 24 h and C-reactive protein, in order to determine the most accurate test for predicting mortality and severity outcomes in AP. Methods. Clinical data of 410 AP patients, prospectively enrolled for study at our institution, were analyzed. We define AP according to Atlanta classification (AC) 2012. The laboratory test’s predictive accuracy was measured using area-under-the-curve receiver-operating characteristics (AUC) analysis and sensitivity and specificity tests. Results. Rise in BUN was the only score related to mortality on the multivariate analysis ( p = 0.000 , OR: 12.7; CI 95%: 4.2−16.6). On the comparative analysis of AUC, the rise in BUN was an accurate test in predicting mortality (AUC: 0.842) and persisting multiorgan failure (AUC: 0.828), similar to the BISAP score (AUC: 0.836 and 0.850) and APACHE-II (AUC: 0.756 and 0.741). The BISAP score outperformed both APACHE-II and rise in BUN at 24 hours in predicting severe AP (AUC: 0.873 vs. 0.761 and 0.756, respectively). Conclusion. Rise in BUN at 24 hours is a quick and reliable test in predicting mortality and persisting multiorgan failure in AP patients.
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Kim, Kyung Han, Byung Geun Kim, Choong Heon Ryu, Hwa Seong Nam, Su Mi Woo, Seung Hee Ryu, Jin Seok Jang, et al. "Comparative analysis of BISAP system and serum procalcitonin for predicting severity of acute pancreatitis." Pancreatology 13, no. 4 (July 2013): S25—S27. http://dx.doi.org/10.1016/j.pan.2013.07.134.

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Jasti, Sirisha, Meira Abramowitz, Mikram Jafri, Javed N. Sadiq, Josmi Joseph, David S. Lee, and Frank G. Gress. "BISAP and CTSI Scores as Predictors of Clinical Outcomes in an African American Cohort." Gastroenterology 140, no. 5 (May 2011): S—855. http://dx.doi.org/10.1016/s0016-5085(11)63548-8.

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Soler, G., E. de-Madaria, I. López-Font, L. Sempere, C. Sánchez-Fortún, J. Martínez, and M. Pérez-Mateo. "PRONÓSTICO AL INGRESO POR PANCREATITIS AGUDA MEDIANTE UN SISTEMA CLÍNICO DE FÁCIL CÁLCULO: BISAP." Gastroenterología y Hepatología 32, no. 3 (March 2009): 239. http://dx.doi.org/10.1016/j.gastrohep.2009.01.132.

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Muthunayagam, Abraham Benjamin, Chitra R, Muruganand Myilsamy, and Vinoth . "Comparison of CTSI and BISAP Scoring in the Assessment of Severity and Mortality in Cases of Acute Pancreatitis." New Indian Journal of Surgery 10, no. 6 (2019): 559–66. http://dx.doi.org/10.21088/nijs.0976.4747.10619.1.

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Modi, Jenish Vijaykumar, and Jenish Sheth. "Observational study of comparison of BISAP score with Ranson’s score and APACHE II scores in assessing severity and prognosis in patients of acute pancreatitis." International Surgery Journal 6, no. 1 (December 27, 2018): 178. http://dx.doi.org/10.18203/2349-2902.isj20185468.

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Background: Acute pancreatitis is one of the most common diseases of gastrointestinal tract, leading to tremendous emotional, physical and financial burden. Acute pancreatitis is an acute inflammation of the prior normal gland parenchyma which is usually reversible (but acute attack can occur in a pre-existing chronic pancreatitis) with raised pancreatic enzyme levels in blood and urine. It may be first attack or relapsing attacks with an apparently normal gland in between. Biliary tract disease and alcoholism are the commonest cause of pancreatitis.Methods: It was an observational study at Surat municipal institute of medical education and research (SMIMER), Department of Surgery. In present study authors used BISAP score, RANSON’S score and APACHE II score to evaluate the severity and mortality in cases of pancreatitis. In present study authors have compare all the scoring system on the basis of CT scan findings. In present study authors have included all patients above age of 18 years. Patient below 18 years of age, acute on chronic pancreatitis and hereditary pancreatitis were not included.Results: In this retrospective study, we found that incidence of colorectal carcinoma is more between 40-60 years of age with male predominance; lymph node metastasis is more than metastasis in any other sites. CT scan can diagnose lymphatic metastasis and infiltration in surrounding tissue more accurately. Percentage of sphincter saving procedure were low in rectal malignancies in our study.Conclusions: All three-scoring system assess the prognosis of the patient, but the prognosis assessed by APACHE II score is better, but for quick and easy assessment, BISAP score is good for prognosis because APACHE II score uses more parameters to assess the prognosis and BISAP score uses less parameters to assess the prognosis.
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García-Revilla, Omar V., Lucy E. Correa-López, Richard I. Rubio-Ramos, and Maria Loo-Valverde. "Comparison of the APACHE II and BISAP scales in the prognosis of acute pancreatitis in a hospital of Peru." Revista de la Facultad de Medicina Humana 20, no. 4 (September 11, 2020): 574–80. http://dx.doi.org/10.25176/rfmh.v20i4.2873.

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Kaplan, Mustafa, Ihsan Ates, Erkin Oztas, Mahmut Yuksel, Muhammed Yener Akpinar, Orhan Coskun, and Ertugrul Kayacetin. "A New Marker to Determine Prognosis of Acute Pancreatitis: PLR and NLR Combination." Journal of Medical Biochemistry 37, no. 1 (January 1, 2018): 21–30. http://dx.doi.org/10.1515/jomb-2017-0039.

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SummaryBackground: We aimed to investigate the prognostic importance of platelet-lymphocyte ratio (PLR) and neutro - phil-lymphocyte ratio(NLR) combination for patients diagnosed with acute pancreatitis and its relationship with mortality. Methods: This retrospective study was included 142 patients diagnosed with acute pancreatitis. Ranson, Atlanta and BISAP 0h, 24h and 48h scores of the patients were calculated by examining their patient files. The patients were divided into three groups as low-risk, medium-risk and high-risk patients according to their PLR and NLR levels. Results: The number of patients with acute pancreatitis complications such as necrotizing pancreatitis, acute renal failure, sepsis and cholangitis was significantly higher in the high-risk group compared to other groups. Mortality rate was found to be 90% in the high-risk group, 16% in the medium-risk group, and 1.9% in the low-risk group. The number of patients with a Ranson score of 5 and 6, a severe Atlanta score, a BISAP 0h score of 3 and 4, a BISAP 24h and 48h score of 4 and 5 was higher in the high-risk group compared to other groups. PLR-NLR combination, Atlanta and Ranson scores, and C-reactive protein level were determined to be independent risk factors predicting mortality in stepwise regression model. PLR-NLR combination had the highest area under curve value in terms of predicting acute claspancreatitis prognosis and had a similar diagnostic discrimination with other scoring systems. Conclusion: In our study it was found that PLR-NLR combination had a similar prognostic importance with other scoring systems used to determine acute pancreatitis prognosis.
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de-Madaria, Enrique, Gema Soler-Sala, Inmaculada Lopez-Font, Laura Gómez-Escolar, Laura Sempere, Cristina Sánchez-Fortún, Juan Martínez, and Miguel Pérez-Mateo. "S1366 Prognostic Scores for Acute Pancreatitis Within 24 Hours of Admission: BISAP Versus APACHE-II." Gastroenterology 138, no. 5 (May 2010): S—238. http://dx.doi.org/10.1016/s0016-5085(10)61082-7.

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Kim, H. K., Y. S. Cho, E. C. Jang, J. O. Yeom, S. Y. Kim, J. Y. Yu, Y. J. Kim, K. R. Do, S. S. Kim, and H. S. Chae. "Usefulness of the BISAP in the early prediction of severity and mortality in acute pancreatitis." Pancreatology 13, no. 2 (March 2013): e43-e44. http://dx.doi.org/10.1016/j.pan.2012.12.207.

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Hagjer, Sumitra, and Nitesh Kumar. "Evaluation of the BISAP scoring system in prognostication of acute pancreatitis – A prospective observational study." International Journal of Surgery 54 (June 2018): 76–81. http://dx.doi.org/10.1016/j.ijsu.2018.04.026.

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Borges, F., S. Silva, N. Carvalho, and P. Costa. "Comparison of HAPS, BISAP and NLR as predictors of severity in acute pancreatitis (Atlanta 2012)." HPB 22 (2020): S273. http://dx.doi.org/10.1016/j.hpb.2020.04.181.

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Hussain, Tanveer, Muhammad Hanif, Ramlah Ghazanfor, Sarmad Arslan, Ibia Nawaz, and Muhammad Umar. "Acute Pancreatitis severity scoring index: Prospective study to identify determinants in Pakistan." Journal of Rawalpindi Medical College 24, no. 3 (September 30, 2020): 264–69. http://dx.doi.org/10.37939/jrmc.v24i3.1412.

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Introduction: The purpose of the study was to compare different parameters used in Ranson’s Criteria, Bedside Index of Severity in Acute Pancreatitis (BISAP), Acute Physiology and Chronic Health Evaluation (APACHE-II), and modified computed tomography severity index (MCTSI) for predicting the severity of acute pancreatitis and formulate a new scoring system to assess the severity of acute pancreatitis based on their prognostic severity index in the local population. Materials and Methods: This prospective pilot study was conducted at Rawalpindi Medical University allied hospitals from August 2019 to December 2019. All patients with a diagnosis of acute pancreatitis were included in the study through non-probability convenient sampling. Different scoring parameters were entered into standardized proforma. Results: 100 patients were included in the pilot study with a mean age of 46.53 ± 15.324. Among 24 parameters from APACHE-II, Ranson’s, BISAP, and MCTSI, only 11 parameters, Pleural effusion (PE), Pancreatic necrosis (PN), LDH, serum Calcium (Sca++), Pulse, GCS, MCTS1, Base deficit, Po2, BUN-24, and BUN-48 were significantly related(at 10% level of significance) with the severity of acute pancreatitis. Similarly out of 24, 10 parameters AST, LDH, Sca++, Pulse, PE, PN, Base deficit, MCTS1, Po2, and BUN 48were significantly covered more than 50% of the area in AUC analysis. Our proposed criteria based on 9 parameters LDH, Sca++, Pulse, PE, PN, Base deficit, MCTS1, Po2, and BUN 48which were blowing by the two methods (ANOVA and ROC). The sensitivity and specificity were higher with our proposed criteria 93.1% and 60.6%respectively as compared to the Ranson’s, modified Ranson, BISAP, and APACHE-II criteria. Conclusion: The newly proposed criteria for the assessment of the severity of AP is superior as compared to old criteria.
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Koziel, Dorota, Stanislaw Gluszek, Jaroslaw Matykiewicz, Piotr Lewitowicz, and Zuzanna Drozdzak. "Comparative Analysis of Selected Scales to Assess Prognosis in Acute Pancreatitis." Canadian Journal of Gastroenterology and Hepatology 29, no. 6 (2015): 299–303. http://dx.doi.org/10.1155/2015/392643.

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OBJECTIVE: To evaluate the utility of selected scales to prognosticate the severity and risk for death among patients with acute pancreatitis (AP) according to the revised Atlanta classification published in 2012.METHODS: Prospective data regarding patients hospitalized due to AP were analyzed. The final analysis included a total of 1014 patients. The bedside index for severity in acute pancreatitis (BISAP), Panc 3 scores and Ranson scales were calculated using data from the first 24 h of admission.RESULTS: Mild AP was diagnosed in 822 (81.1%) cases, moderate in 122 (12%) and severe in 70 (6.9%); 38 (3.7%) patients died. The main causes of AP were cholelithiasis (34%) and alcohol abuse (26.7%). Recurrence of AP was observed in 244 (24.1%) patients. In prognosticating the severity of AP, the most useful scale proved to be the Acute Physiology and Chronic Health Evaluation (APACHE) II (area under the curve [AUC] 0.724 [95% CI 0.655 to 0.793]), followed by BISAP (AUC 0.693 [95% CI 0.622 to 0.763]). In prognosticating a moderate versus mild course of AP, the CT severity index proved to be the most decisive (AUC 0.819 [95% CI 0.767 to 0.871]). Regarding prognosis for death, APACHE II had the highest predictive value (AUC 0.726 [95% CI 0.621 to 0.83]); however, a similar sensitivity was observed using the BISAP scale (AUC 0.707 [95% CI 0.618 to 0.797]).CONCLUSIONS: Scoring systems used in prognosticating the course of the disease vary with regard to sensitivity and specificity. The CT severity index scoring system showed the highest precision in prognosticating moderately severe AP (as per the revised Atlanta criteria, 2012); however, in prognosticating a severe course of disease and mortality, APACHE II proved to have the greatest predictive value.
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Vaz, Pedro Silva, Ana Caldeira, Rui Sousa, Antonio Gouveia, Antonio Banhudo, and Arnandina Loureiro. "The value of procalcitonin, antithrombin III and BISAP score at predicting the severity of acute pancreatitis." Pancreatology 13, no. 3 (May 2013): S34—S35. http://dx.doi.org/10.1016/j.pan.2013.04.113.

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Kim, Byung Geun, Myung Hwan Noh, Choong Heon Ryu, Hwa Seong Nam, Su Mi Woo, Seung Hee Ryu, Jin Seok Jang, Jong Hun Lee, Seok Ryeol Choi, and Byeong Ho Park. "A comparison of the BISAP score and serum procalcitonin for predicting the severity of acute pancreatitis." Korean Journal of Internal Medicine 28, no. 3 (2013): 322. http://dx.doi.org/10.3904/kjim.2013.28.3.322.

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Valverde-López, Francisco, Ana M. Matas-Cobos, Carlos Alegría-Motte, Rita Jiménez-Rosales, Margarita Úbeda-Muñoz, and Eduardo Redondo-Cerezo. "BISAP, RANSON, lactate and others biomarkers in prediction of severe acute pancreatitis in a European cohort." Journal of Gastroenterology and Hepatology 32, no. 9 (August 28, 2017): 1649–56. http://dx.doi.org/10.1111/jgh.13763.

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Sudarshan, N., and P. Narasimha Swamy. "Assessment of severity of acute pancreatitis with bedside index for severity in acute pancreatitis (BISAP) score." IP Journal of Surgery and Allied Sciences 3, no. 1 (May 15, 2021): 13–17. http://dx.doi.org/10.18231/j.jsas.2021.004.

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