Academic literature on the topic 'Bischler napieralski reaction'

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Journal articles on the topic "Bischler napieralski reaction"

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Puerto Galvis, Carlos, Mario Macías, and Vladimir Kouznetsov. "Unexpected PF6 Anion Metathesis during the Bischler–Napieralski Reaction: Synthesis of 3,4-Dihydroisoquinoline Hexafluorophosphates and Their Tetrahydroisoquinoline Related Alkaloids." Synthesis 51, no. 09 (2019): 1949–60. http://dx.doi.org/10.1055/s-0037-1610684.

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A series of N-phenethylcinnamamides were subjected to the Bischler–Napieralski reaction to furnish diverse 1-styryl-3,4-dihydroisoquinolines. We noticed that the desired products were unstable when the reaction was performed under conventional solvent conditions. However, when [bmim]PF6 was used as the reaction media, the nature of the Bischler–Napieralski reaction promoted an unusual in situ ionic interchange between this ionic liquid and the dihydroisoquinoline core that led to the stabilization of the desired 1-styryl-3,4-dihydroisoquinolines, allowing their isolation as hexafluorophosphate
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Kim, Kyung-Hee, and Cheol-Hong Cheon. "Concise catalytic asymmetric total syntheses of ancistrocladinium A and its atropdiastereomer." Organic Chemistry Frontiers 4, no. 7 (2017): 1341–49. http://dx.doi.org/10.1039/c7qo00195a.

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Faltracco, Matteo, and Eelco Ruijter. "Synthesis of tetracyclic spiroindolines by an interrupted Bischler–Napieralski reaction: total synthesis of akuammicine." Organic & Biomolecular Chemistry 19, no. 44 (2021): 9641–44. http://dx.doi.org/10.1039/d1ob01966j.

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The interrupted Bischler–Napieralski reaction of β,γ-unsaturated tryptamides affords tetracyclic spiro pyrroloindolines, which can be used in the total synthesis of the Strychnos alkaloid, akuammicine.
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Gouda, Moustafa A., Ameen A. Abu-Hashem, and Ahmed A. M. Abdelgawad. "Thieno[3,2-c] Quinoline Heterocyclic Synthesis and Reactivity Part (VI)." Mini-Reviews in Organic Chemistry 19, no. 5 (2022): 629–53. http://dx.doi.org/10.2174/1570193x18666211004102537.

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Abstract: The biological and medicinal properties of thieno[3, 2-c] quinoline have prompted enormous research aimed at developing synthetic routes for these systems. This review focuses on the chemical properties associated with this system. The most reported reactions are Bischler- Napieralski, Suzuki−Miyaura−Schlüter, Pictet-Spengler, Stille coupling and Friedlander and Beckmann rearrangement reaction.
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Gouda, Moustafa A., Ameen A. Abu-Hashem, and Ahmed A. M. Abdelgawad. "Thieno[3,2-c] Quinoline Heterocyclic Synthesis and Reactivity Part (VI)." Mini-Reviews in Organic Chemistry 19, no. 5 (2022): 629–53. http://dx.doi.org/10.2174/1570193x18666211004102537.

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Abstract: The biological and medicinal properties of thieno[3, 2-c] quinoline have prompted enormous research aimed at developing synthetic routes for these systems. This review focuses on the chemical properties associated with this system. The most reported reactions are Bischler- Napieralski, Suzuki−Miyaura−Schlüter, Pictet-Spengler, Stille coupling and Friedlander and Beckmann rearrangement reaction.
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Abu-Safieh, Kayed A., Mustafa M. El-Abadelah, Salim S. Sabri, Wolfgang Voelter, Cäcilia M. Mössmer та Markus Stroebele. "Bischler-Napieralski Synthesis of Some New Pyrazole-Fused β-Carbolines". Zeitschrift für Naturforschung B 57, № 11 (2002): 1327–32. http://dx.doi.org/10.1515/znb-2002-1120.

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3-(4-Acylaminopyrazol-5-yl)-4-methylindoles (13a,b), under Bischler-Napieralski reaction conditions, undergo cyclization at the pyrrolic carbon-2 with ultimate formation of the corresponding pyrazolo[3,4:5′,6′]pyrido[3,4-b]indoles (14a,b) as evidenced by crystal structure analysis of 14a.
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Ishikawa, Tsutomu, Tatsuru Saito, and Makoto Yoshida. "Triphosgene: A Versatile Reagent for Bischler-Napieralski Reaction." HETEROCYCLES 54, no. 1 (2001): 437. http://dx.doi.org/10.3987/com-00-s(i)44.

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Ramesh, D., and M. Srinivasan. "Phosphonitrilic Chloride - A Reagent for Bischler-Napieralski Reaction." Synthetic Communications 16, no. 12 (1986): 1523–27. http://dx.doi.org/10.1080/00397918608056405.

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Muratov, A. V., S. A. Grebenyuk, and A. B. Eresko. "Synthesis of 1,2-Diazepines by the Bischler–Napieralski Reaction." Russian Journal of Organic Chemistry 54, no. 6 (2018): 861–66. http://dx.doi.org/10.1134/s1070428018060064.

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Meruva, Suresh Babu, Akula Raghunadh, Raghavendra Rao Kamaraju, U. K. Syam Kumar та P. K. Dubey. "An oxidative amidation and heterocyclization approach for the synthesis of β-carbolines and dihydroeudistomin Y". Beilstein Journal of Organic Chemistry 10 (25 лютого 2014): 471–80. http://dx.doi.org/10.3762/bjoc.10.45.

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A novel synthetic methodology has been developed for the synthesis of dihydro-β-carboline derivatives employing oxidative amidation–Bischler–Napieralski reaction conditions using tryptamine and 2,2-dibromo-1-phenylethanone as key starting materials. A number of dihydro-β-carboline derivatives have been synthesized in moderate to good yields using this methodology. Attempts were made towards the conversion of these dihydro-β-carbolines to naturally occurring eudistomin alkaloids.
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Dissertations / Theses on the topic "Bischler napieralski reaction"

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White, Kolby Lyn. "Mechanistic investigation of the interrupted Bischler-Napieralski reaction and its application to the total synthesis of the aspidosperma alkaloids." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/109682.

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Thesis: Ph. D. in Organic Chemistry, Massachusetts Institute of Technology, Department of Chemistry, 2017.<br>Vita. Scanning issues: Page 114 contains text that has been cropped/deleted from the right-side page margin. Appendix B section contains several graph pages with faint/illegible images. Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>I. Direct Observation of Intermediates Involved in the Interruption of the Bischler- Napieralski Reaction. The first mechanistic investigation of electrophilic amide activation of [alpha], [alpha]-disubstituted tertiary lac
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Medley, Jonathan William. "Direct dehydrative N-Pyridinylation of amides, the interrupted Bischler-Napieralski reaction, and the enantioselective total synthesis and arylative dimerization of aspidosperma alkaloids." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/82319.

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Thesis (Ph. D. in Organic Chemistry)--Massachusetts Institute of Technology, Dept. of Chemistry, 2013.<br>Cataloged from PDF version of thesis. Vita.<br>Includes bibliographical references.<br>I. Direct Dehydrative N-Pyridinylation of Amides A method for the single-step N-pyridinylation of secondary amides is described. The process involves electrophilic activation of secondary amides with trifluoromethanesulfonic anhydride in the presence of 2-fluoropyridine followed by introduction of a pyridine N-oxide derivative and warming to afford the corresponding N-pyridinyl tertiary amide derivatives
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Haelters, Jean-Pierre. "Synthèse de dérivés phosphono-indoliques-benzofuranniques et -pyrroliques à partir d'hydrazones phosphonates." Brest, 1987. http://www.theses.fr/1987BRES2002.

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Des derives phosphonoindoliques sont prepares par cyclisation d'arylhydrazones d'oxoalkylphosphonates selon fisher et par cyclodeshydratation d'arylamino-1 et arylamino-3 oxo-2 propylphosphonates selon bischler. Des indolyl-2 et indolyl-3 phosphonates, des indolylmethyl-2 et des indolylmethyl-3 phosphonates diversement substitues et leurs acides phosphoniques correspondants sont decrits. Toutes structures sont analysees par rmn **(1)h, **(31)p et 1**(3)c. L'analogue phosphore de l'intermediaire a aussi ete prepare. L'extention de la reaction de bischler aux aryloxycetones permet d'atteindre de
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Book chapters on the topic "Bischler napieralski reaction"

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Li, Jie Jack. "Bischler-Napieralski reaction." In Name Reactions. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05336-2_30.

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Li, Jie Jack. "Bischler–Napieralski reaction." In Name Reactions. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-03979-4_27.

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Li, Jie Jack. "Bischler-Napieralski reaction." In Name Reactions. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04835-1_28.

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Li, Jie Jack. "Bischler–Napieralski reaction." In Name Reactions. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-01053-8_23.

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Li, Jie Jack. "Bischler–Napieralski Reaction." In Name Reactions. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-50865-4_15.

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Heravi, Majid M., Soheila Khaghaninejad, and Niousha Nazari. "Bischler–Napieralski Reaction in the Syntheses of Isoquinolines∗." In Advances in Heterocyclic Chemistry. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-800171-4.00005-6.

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Rohloff, J. C., N. H. Dyson, J. O. Gardner, T. V. Alfredson, M. L. Sparacino, and J. Robinson III,. "Total Synthesis of RS-15385." In Exercises in Synthetic Organic Chemistry. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198559443.003.0003.

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Abstract Discussion Points What is the mechanism of the Bischler–Napieralski reaction of step b? Suggest a reason why less hindered bases could not be used in step f. Propose structures for the minor diastereomers obtained during the hydrogenation step g. Suggest a derivatising agent for the HPLC analysis of the optical purity of the 10-camphorsulphonic acid salt obtained in step h. Further Reading For reviews on isoquinoline alkaloids synthesis, see: M. D. Rozwadowska, Heterocycles,1994, 39,903; E. D. Cox and J.M. Cook, Chem. Rev.,1995, 95,1797. For a review on chiral derivatising agents, see
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