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1

Puerto Galvis, Carlos, Mario Macías, and Vladimir Kouznetsov. "Unexpected PF6 Anion Metathesis during the Bischler–Napieralski Reaction: Synthesis of 3,4-Dihydroisoquinoline Hexafluorophosphates and Their Tetrahydroisoquinoline Related Alkaloids." Synthesis 51, no. 09 (February 18, 2019): 1949–60. http://dx.doi.org/10.1055/s-0037-1610684.

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A series of N-phenethylcinnamamides were subjected to the Bischler–Napieralski reaction to furnish diverse 1-styryl-3,4-dihydroisoquinolines. We noticed that the desired products were unstable when the reaction was performed under conventional solvent conditions. However, when [bmim]PF6 was used as the reaction media, the nature of the Bischler–Napieralski reaction promoted an unusual in situ ionic interchange between this ionic liquid and the dihydroisoquinoline core that led to the stabilization of the desired 1-styryl-3,4-dihydroisoquinolines, allowing their isolation as hexafluorophosphate salts. Finally, the one-pot reduction/reductive methylation process afforded the N-methyl derivatives, establishing that our findings can be an efficient and useful strategy for the concise synthesis of tetrahydroisoquinoline alkaloids.
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2

Kim, Kyung-Hee, and Cheol-Hong Cheon. "Concise catalytic asymmetric total syntheses of ancistrocladinium A and its atropdiastereomer." Organic Chemistry Frontiers 4, no. 7 (2017): 1341–49. http://dx.doi.org/10.1039/c7qo00195a.

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3

Ishikawa, Tsutomu, Tatsuru Saito, and Makoto Yoshida. "Triphosgene: A Versatile Reagent for Bischler-Napieralski Reaction." HETEROCYCLES 54, no. 1 (2001): 437. http://dx.doi.org/10.3987/com-00-s(i)44.

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4

Ramesh, D., and M. Srinivasan. "Phosphonitrilic Chloride - A Reagent for Bischler-Napieralski Reaction." Synthetic Communications 16, no. 12 (October 1986): 1523–27. http://dx.doi.org/10.1080/00397918608056405.

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5

Abu-Safieh, Kayed A., Mustafa M. El-Abadelah, Salim S. Sabri, Wolfgang Voelter, Cäcilia M. Mössmer, and Markus Stroebele. "Bischler-Napieralski Synthesis of Some New Pyrazole-Fused β-Carbolines." Zeitschrift für Naturforschung B 57, no. 11 (November 1, 2002): 1327–32. http://dx.doi.org/10.1515/znb-2002-1120.

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3-(4-Acylaminopyrazol-5-yl)-4-methylindoles (13a,b), under Bischler-Napieralski reaction conditions, undergo cyclization at the pyrrolic carbon-2 with ultimate formation of the corresponding pyrazolo[3,4:5′,6′]pyrido[3,4-b]indoles (14a,b) as evidenced by crystal structure analysis of 14a.
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6

Muratov, A. V., S. A. Grebenyuk, and A. B. Eresko. "Synthesis of 1,2-Diazepines by the Bischler–Napieralski Reaction." Russian Journal of Organic Chemistry 54, no. 6 (June 2018): 861–66. http://dx.doi.org/10.1134/s1070428018060064.

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7

Meruva, Suresh Babu, Akula Raghunadh, Raghavendra Rao Kamaraju, U. K. Syam Kumar, and P. K. Dubey. "An oxidative amidation and heterocyclization approach for the synthesis of β-carbolines and dihydroeudistomin Y." Beilstein Journal of Organic Chemistry 10 (February 25, 2014): 471–80. http://dx.doi.org/10.3762/bjoc.10.45.

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A novel synthetic methodology has been developed for the synthesis of dihydro-β-carboline derivatives employing oxidative amidation–Bischler–Napieralski reaction conditions using tryptamine and 2,2-dibromo-1-phenylethanone as key starting materials. A number of dihydro-β-carboline derivatives have been synthesized in moderate to good yields using this methodology. Attempts were made towards the conversion of these dihydro-β-carbolines to naturally occurring eudistomin alkaloids.
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8

Han, Yi, Zhenzhu Hu, Meifang Liu, Mengwei Li, Tingting Wang, and Yulan Chen. "Synthesis, Characterization, and Properties of Diazapyrenes via Bischler–Napieralski Reaction." Journal of Organic Chemistry 84, no. 7 (February 26, 2019): 3953–59. http://dx.doi.org/10.1021/acs.joc.8b03096.

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9

Syam Kumar, U., R. Shankar, Satish More, M. Madhubabu, and N. Vembu. "Synthesis of Isoquinoline Alkaloids via Oxidative Amidation-Bischler-Napieralski Reaction." Synlett 23, no. 07 (March 28, 2012): 1013–20. http://dx.doi.org/10.1055/s-0031-1290655.

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10

Saito, Tatsuru, Makoto Yoshida, and Tsutomu Ishikawa. "ChemInform Abstract: Triphosgene: A Versatile Reagent for Bischler-Napieralski Reaction." ChemInform 32, no. 23 (May 26, 2010): no. http://dx.doi.org/10.1002/chin.200123139.

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11

Heravi, Majid M., Soheila Khaghaninejad, and Niousha Nazari. "ChemInform Abstract: Bischler-Napieralski Reaction in the Synthesis of Isoquinolines." ChemInform 46, no. 25 (June 2015): no. http://dx.doi.org/10.1002/chin.201525257.

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12

Faltracco, Matteo, Said Ortega-Rosales, Elwin Janssen, Răzvan C. Cioc, Christophe M. L. Vande Velde, and Eelco Ruijter. "Synthesis of Carbazoles by a Diverted Bischler–Napieralski Cascade Reaction." Organic Letters 23, no. 8 (March 31, 2021): 3100–3104. http://dx.doi.org/10.1021/acs.orglett.1c00785.

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13

Medley, Jonathan William, and Mohammad Movassaghi. "Synthesis of Spirocyclic Indolines by Interruption of the Bischler–Napieralski Reaction." Organic Letters 15, no. 14 (July 5, 2013): 3614–17. http://dx.doi.org/10.1021/ol401465y.

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14

Guo, Hong-shuang, Mei-fang Liu, Yi Han, Sheng Han, and Yu-lan Chen. "Synthesis and characterization of S,N-heteroacenes by Bischler-Napieralski reaction." Chinese Journal of Polymer Science 34, no. 11 (September 28, 2016): 1319–29. http://dx.doi.org/10.1007/s10118-016-1846-9.

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15

Sano, Takehiro, Jun Toda, Nobuteru Maehara, and Yoshisuke Tsuda. "Synthesis of erythrina and related alkaloids. 17. Total synthesis of dl-coccuvinine and dl-coccolinine." Canadian Journal of Chemistry 65, no. 1 (January 1, 1987): 94–98. http://dx.doi.org/10.1139/v87-015.

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Total synthesis of dl-coccuvinine 1a and dl-coccolinine 2a, "abnormal-type" erythrinan alkaloids lacking the C(16) O-function at the aromatic ring, was effectively achieved by using the Diels–Alder reaction of dioxopyrroline. Isoquinolinopyrrolinedione 6a, a key dienophile, was synthesized via the tetrahydroisoquinoline 5a, which was prepared by Bischler–Napieralski cyclization of the amide 4a at the unactivated position. The Diels–Alder adduct 7a of 1,3-bis(trimethylsilyloxy)-butadiene with 6a with converted stereoselectively into these alkaloids in short steps.
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16

Tietze, Lutz F., and Nils Rackelmann. "Enantioselective Synthesis of Epi-Emetine Analogues: Control of the Facial Selectivity in a Three-Component Domino Knoevenagel-Hetero-Diels-Alder Reaction*." Zeitschrift für Naturforschung B 59, no. 4 (April 1, 2004): 468–77. http://dx.doi.org/10.1515/znb-2004-0415.

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AbstractThe domino Knoevenagel-hetero-Diels-Alder reaction of the aldehyde rac-8, Meldrum’s acid 2 and enol ether 3 leads to the cycloadduct rac-17 as the main product which in a second domino process was transformed into the benzoisoquinolizidine rac-18 by solvolysis, hydrogenolysis, condensation and hydrogenation; rac-18 was used as a substrate for the synthesis of the two diastereomeric epiemetine analogues 9 and 10 with > 96% ee (9) and 80% ee (10), respectively, by condensation with the phenylethylamine 23, Bischler-Napieralski reaction and “enantioselective” hydrogenation using the chiral catalyst (R,R)-26.
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17

Shankar, R., Satish S. More, M. V. Madhubabu, N. Vembu, and U. K. Syam Kumar. "ChemInform Abstract: Synthesis of Isoquinoline Alkaloids via Oxidative Amidation/Bischler-Napieralski Reaction." ChemInform 43, no. 33 (July 19, 2012): no. http://dx.doi.org/10.1002/chin.201233208.

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18

White, Kolby L., Marius Mewald, and Mohammad Movassaghi. "Direct Observation of Intermediates Involved in the Interruption of the Bischler–Napieralski Reaction." Journal of Organic Chemistry 80, no. 15 (July 22, 2015): 7403–11. http://dx.doi.org/10.1021/acs.joc.5b01023.

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19

Amer, Mostafa M., Olatz Olaizola, Jennifer Carter, Hossay Abas, and Jonathan Clayden. "An Aliphatic Bischler–Napieralski Reaction: Dihydropyridones by Cyclocarbonylation of 3-Allylimidazolidin-4-ones." Organic Letters 22, no. 1 (December 17, 2019): 253–56. http://dx.doi.org/10.1021/acs.orglett.9b04250.

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20

Ishikawa, Tsutomu, Kazunari Shimooka, Tomoko Narioka, Shigeru Noguchi, Tatsuru Saito, Akiko Ishikawa, Emi Yamazaki, Takashi Harayama, Hiroko Seki, and Kentaro Yamaguchi. "Anomalous Substituent Effects in the Bischler−Napieralski Reaction of 2-Aryl Aromatic Formamides." Journal of Organic Chemistry 65, no. 26 (December 2000): 9143–51. http://dx.doi.org/10.1021/jo0012849.

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21

Nicoletti, Marcello, David O'Hagan, and Alexandra M. Z. Slawin. "ChemInform Abstract: The Asymmetric Bischler-Napieralski Reaction: Preparation of 1,3,4-Trisubstituted 1,2,3,4-Tetrahydroisoquinolines." ChemInform 33, no. 20 (May 21, 2010): no. http://dx.doi.org/10.1002/chin.200220116.

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22

Medley, Jonathan, and Mohammad Movassaghi. "ChemInform Abstract: Synthesis of Spirocyclic Indoles by Interruption of the Bischler-Napieralski Reaction." ChemInform 44, no. 50 (November 21, 2013): no. http://dx.doi.org/10.1002/chin.201350120.

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23

Muraoka, Osamu, Tomohisa Yasuhara, Naoko Zaima, and Masako Yamazaki. "First Total Synthesis of Crispine B by Nitro Aldol and the Bischler-Napieralski Reaction." HETEROCYCLES 77, no. 2 (2009): 1397. http://dx.doi.org/10.3987/com-08-s(f)104.

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24

Heaney, Harry, Khamis F. Shuhaibar, and Alexandra M. Z. Slawin. "The capture of acetonitrile during a bischler-napieralski cyclisation reaction of an oxamide derivative." Tetrahedron Letters 37, no. 24 (June 1996): 4275–76. http://dx.doi.org/10.1016/0040-4039(96)00815-5.

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25

M. Heravi, Majid, and Niousha Nazari. "Bischler-Napieralski Reaction in Total Synthesis of Isoquinoline-based Natural Products. An Old Reaction, a New Application." Current Organic Chemistry 19, no. 24 (October 13, 2015): 2358–408. http://dx.doi.org/10.2174/1385272819666150730214506.

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26

Seganish, W. Michael, Ana Bercovici, Ginny D. Ho, Hubert J. J. Loozen, Cornelis M. Timmers, and Deen Tulshian. "A synthesis of dihydroimidazo[5,1-a]isoquinolines using a sequential Ugi–Bischler–Napieralski reaction sequence." Tetrahedron Letters 53, no. 8 (February 2012): 903–5. http://dx.doi.org/10.1016/j.tetlet.2011.12.050.

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27

Ishikawa, Tsutomu, Kazunari Shimooka, Tomoko Narioka, Shigeru Noguchi, Tatsuru Saito, Akiko Ishikawa, Emi Yamazaki, Takashi Harayama, Hiroko Seki, and Kentaro Yamaguchi. "ChemInform Abstract: Anomalous Substituent Effects in the Bischler-Napieralski Reaction of 2-Aryl Aromatic Formamides." ChemInform 32, no. 19 (May 8, 2001): no. http://dx.doi.org/10.1002/chin.200119104.

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28

Mandrekar, Ketan S., Hari K. Kadam, and Santosh G. Tilve. "Domino Bischler-Napieralski - Michael Reaction and Oxidation - New Route to Coumarin-Pyrrole-Isoquinoline Fused Pentacycles." European Journal of Organic Chemistry 2018, no. 47 (December 5, 2018): 6665–70. http://dx.doi.org/10.1002/ejoc.201801244.

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29

Chen, Yulan, Weiguo Huang, Cuihong Li, and Zhishan Bo. "Synthesis of Fully Soluble Azomethine-Bridged Ladder-Type Poly(p-phenylenes) by Bischler−Napieralski Reaction." Macromolecules 43, no. 24 (December 28, 2010): 10216–20. http://dx.doi.org/10.1021/ma1021117.

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30

Pal, Bikash, Parasuraman Jaisankar, Venkatachalam Sesha Giri, Swastik Mondal, and Monika Mukherjee. "Unusual formation of β-carboline dimers under Bischler–Napieralski reaction conditions: an old reaction with a new direction." Tetrahedron Letters 45, no. 34 (August 2004): 6489–92. http://dx.doi.org/10.1016/j.tetlet.2004.06.118.

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31

Aguirre, J. M., E. N. Alesso, A. F. Ibañez, D. G. Tombari, and G. Y. Moltrasio Iglesias. "Reaction of 1,2-diarylethylamides with ethyl polyphosphate (Epp): Correlation of the von braun, ritter and bischler-napieralski reactions." Journal of Heterocyclic Chemistry 26, no. 1 (January 1989): 25–27. http://dx.doi.org/10.1002/jhet.5570260106.

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32

Sotomayor, N., E. Domínguez, and E. Lete. "Bischler-Napieralski Reaction of C2′, Functionalized 1,2-Diarylethylamides: A General Approach to the Synthesis of Protoberberines." Synlett 1993, no. 06 (1993): 431–33. http://dx.doi.org/10.1055/s-1993-22484.

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33

Wang, Shuang‐Hu, Rui‐Qi Si, Qing‐Bo Zhuang, Xiang Guo, Tian Ke, Xiao‐Ming Zhang, Fu‐Min Zhang, and Yong‐Qiang Tu. "Collective Total Synthesis of Aspidofractinine Alkaloids through the Development of a Bischler–Napieralski/Semipinacol Rearrangement Reaction." Angewandte Chemie 132, no. 49 (September 29, 2020): 22138–42. http://dx.doi.org/10.1002/ange.202009238.

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34

Wang, Shuang‐Hu, Rui‐Qi Si, Qing‐Bo Zhuang, Xiang Guo, Tian Ke, Xiao‐Ming Zhang, Fu‐Min Zhang, and Yong‐Qiang Tu. "Collective Total Synthesis of Aspidofractinine Alkaloids through the Development of a Bischler–Napieralski/Semipinacol Rearrangement Reaction." Angewandte Chemie International Edition 59, no. 49 (September 29, 2020): 21954–58. http://dx.doi.org/10.1002/anie.202009238.

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35

Butin, Alexander, Fatima Tsiunchik, Olga Kostyukova, Maxim Uchuskin, and Igor Trushkov. "Furan Ring Opening - Pyridine Ring Closure: New Route to Quinolines under the Bischler-Napieralski Reaction Conditions." Synthesis 2011, no. 16 (July 14, 2011): 2629–38. http://dx.doi.org/10.1055/s-0030-1260118.

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36

Padwa, Albert, and Thomas S. Reger. "Construction of bicyclic tetrahydroisoquinolinones by combination of an IMDAF-ring cleavage reaction of N-allyl-2-furan-2-yl-acetamides." Canadian Journal of Chemistry 78, no. 6 (June 1, 2000): 749–56. http://dx.doi.org/10.1139/v99-234.

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The intramolecular Diels-Alder reaction of furanyl amides derived from 2-furylacetic acid has been examined. Substrates containing either an imide or tertiary amide linkage between the furan and the dienophile underwent smooth cycloaddition upon thermolysis. By varying the reaction conditions, either the primary cycloadduct or the ring-opened and acetylated product could be isolated in excellent yield. The stereochemical outcome of the IMDAF cycloaddition has the side arm of the tethered alkenyl group oriented syn with respect to the oxygen bridge. Semi-empirical AM1 calculations show that the exo-cycloadduct is 11 kcal lower in energy than the corresponding endo adduct and, presumably, some of this energy difference is reflected in the transition state for the cycloaddition. The IMDAF reaction of N-allyl-[2-(3,4-dimethoxyphenethyl)]-2-furanyl-2-yl-acetamide proceeded in 90% yield upon heating in xylene. The 4+2-cycloadduct undergoes ring-opening on treatment with base and the resulting alcohol was converted into the corresponding benzyl ether. Raney nickel reduction followed by Bischler-Napieralski cyclization furnished the tetracyclic skeleton of the berberine alkaloids.Key words: intramolecular, cycloaddition, Diels-Alder, furanylamide, heterocycle.
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37

Xu, Xianxiu, Sigen Guo, Qun Dang, Jin Chen, and Xu Bai. "A New Strategy toward Fused-Pyridine Heterocyclic Scaffolds: Bischler−Napieralski-type Cyclization, Followed by Sulfoxide Extrusion Reaction." Journal of Combinatorial Chemistry 9, no. 5 (September 2007): 773–82. http://dx.doi.org/10.1021/cc0700389.

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38

Kawabata, Yuki, Yu Naito, Tsuyoshi Saitoh, Kohei Kawa, Toshio Fuchigami, and Shigeru Nishiyama. "Synthesis of (+)-O-Methylthalibrine by Employing a Stereocontrolled Bischler-Napieralski Reaction and an Electrochemically Generated Diaryl Ether." European Journal of Organic Chemistry 2014, no. 1 (November 13, 2013): 99–104. http://dx.doi.org/10.1002/ejoc.201301128.

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39

Seganish, W. Michael, Ana Bercovici, Ginny D. Ho, Hubert J. J. Loozen, Cornelis M. Timmers, and Deen Tulshian. "ChemInform Abstract: A Synthesis of Dihydroimidazo[5,1-a]isoquinolines Using a Sequential Ugi-Bischler-Napieralski Reaction Sequence." ChemInform 43, no. 24 (May 21, 2012): no. http://dx.doi.org/10.1002/chin.201224156.

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40

Butin, Alexander V., Fatima A. Tsiunchik, Olga N. Kostyukova, Maxim G. Uchuskin, and Igor V. Trushkov. "ChemInform Abstract: Furan Ring Opening - Pyridine Ring Closure: New Route to Quinolines under the Bischler-Napieralski Reaction Conditions." ChemInform 42, no. 52 (December 1, 2011): no. http://dx.doi.org/10.1002/chin.201152153.

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41

SOTOMAYOR, N., E. DOMINGUEZ, and E. LETE. "ChemInform Abstract: Bischler-Napieralski Reaction of C2′ Functionalized 1,2- Diarylethylamides: A General Approach to the Synthesis of Protoberberines." ChemInform 25, no. 5 (August 19, 2010): no. http://dx.doi.org/10.1002/chin.199405177.

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42

Ishikawa, Tsutomu, and Tomoko Narioka. "Further Approaches to Anomalous Carbon Insertion into a Benzene Ring in the Bischler-Napieralski Reaction of Phenolic 2-Phenylformanilides." HETEROCYCLES 56, no. 1-2 (2002): 413. http://dx.doi.org/10.3987/com-01-s(k)62.

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43

Biswas, K. M., R. N. Dhara, S. Halder, H. Mallik, A. Sinha-Chaudhuri, P. De, and A. S. Brahmachari. "Novel Products from Bischler-Napieralski Reaction of Arylacetyl-Tryptophan Esters. Synthesis of Spiropentacyclic Indolines Structurally Related to Indole Alkaloids." Synthetic Communications 23, no. 3 (February 1993): 379–88. http://dx.doi.org/10.1080/00397919308009792.

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44

Sanchez-Sancho, Francisco, Enrique Mann, and Bernardo Herradon. "ChemInform Abstract: Efficient Syntheses of Polyannular Heterocycles Featuring Microwave-Accelerated Bischler-Napieralski Reaction, Stereoselective Heck Cyclization, and Claisen Rearrangement." ChemInform 31, no. 30 (June 7, 2010): no. http://dx.doi.org/10.1002/chin.200030126.

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45

Markovich, Kimberly M., Akihiko Hamada, and Duane D. Miller. "A new and unexpected aminoisoquinoline formed under bischler-napieralski reaction conditions provides for A new synthesis of 3-aminoisoquinolines." Journal of Heterocyclic Chemistry 27, no. 6 (September 1990): 1665–67. http://dx.doi.org/10.1002/jhet.5570270628.

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46

Kawabata, Yuki, Yu Naito, Tsuyoshi Saitoh, Kohei Kawa, Toshio Fuchigami, and Shigeru Nishiyama. "ChemInform Abstract: Synthesis of (+)-O-Methylthalibrine by Employing a Stereocontrolled Bischler-Napieralski Reaction and an Electrochemically Generated Diaryl Ether." ChemInform 45, no. 25 (June 5, 2014): no. http://dx.doi.org/10.1002/chin.201425211.

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47

Banwell, MG, and CJ Cowden. "Convergent Routes to the [1,3]Dioxolo[4,5-j]phenanthridin-6(5H)-one and 2,3,4,4a-Tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(5H)-one Nuclei. Application to Syntheses of the Amaryllidaceae Alkaloids Crinasiadine, N-Methylcrinasiadine and Trisphaeridine." Australian Journal of Chemistry 47, no. 12 (1994): 2235. http://dx.doi.org/10.1071/ch9942235.

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Convergent routes to the title nuclei, (1) and (6), have been developed. Thus, Suzuki coupling of boronic acid (8) with aryl bromide (9) gave the biarylylcarbamate (7) which, on treatment with phosphorus oxychloride (POCl3), underwent Bischler-Napieralski cyclization to give, after acid hydrolysis, the Amaryllidaceae alkaloid crinasiadine (1). The cyclization reaction proceeds via an intermediate chlorophenanthridine (11) which can be isolated and N- methylated. Hydrolysis of the resulting iminium species (17) then afforded N- methylcrinasiadine (2). On the other hand, hydrogenolytic dechlorination of compound (II) affords trisphaeridine (14). Related chemistry has been employed in the preparation of 2,3,4,4a-tetrahydro[1,3] dioxolo [4,5-j]phenanthridin-6(5H)-one (6), the tetracyclic skeleton associated with the narcissus alkaloids lycoricidine (3) and narciclasine (4). Thus, treatment of the gem- dibromocyclopropane (20) with silver cyanate resulted in ring opening thereby affording the allylic isocyanate (25) which could be intercepted with added methanol to give carbamate (24). Suzuki coupling of this last compound with boronic acid (8) gave product (18) which was subjected to treatment with and resulted in the formation of (�)-(6). This latter sequence could be adapted to the preparation of both (R)-(6) and (S)-(6).
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48

Ohishi, Yoshitaka, Naomi Hashimoto, Kumiko Miyatani, Keiko Ohkita, Jun-ichi Kunitomo, Ikuo Kawasaki, Masayuki Yamashita, and Shunsaku Ohta. "Bischler-Napieralski Reaction of N-[2-(2-Bromo-4,5-dialkyloxyphenyl)- ethyl]-N-(1-phenylethyl)-2-(2-bromo-4,5-dimethoxyphenyl)acetamides." HETEROCYCLES 57, no. 11 (2002): 2149. http://dx.doi.org/10.3987/com-02-9586.

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49

BISWAS, K. M., R. N. DHARA, S. HALDER, H. MALLIK, A. SINHA-CHAUDHURI, P. DE, and A. S. BRAHMACHARI. "ChemInform Abstract: Novel Products from Bischler-Napieralski Reaction of Arylacetyltryptophan Esters. Synthesis of Spiropentacyclic Indolines Structurally Related to Indole Alkaloids." ChemInform 24, no. 32 (August 20, 2010): no. http://dx.doi.org/10.1002/chin.199332251.

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BASANAGOUDAR, L. D., C. S. MAHAJANSHETTI, and S. B. DAMBAL. "ChemInform Abstract: Synthesis of 11-Methyl/Phenyl-4,5-dihydro-3H-1,4-diazepino(1,2-a) indoles via Bischler-Napieralski-Type Reaction." ChemInform 23, no. 4 (August 22, 2010): no. http://dx.doi.org/10.1002/chin.199204220.

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