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Journal articles on the topic 'Blé'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 June 2025

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1

Sriyanti, Ida, Muhammad Rama Almafie, Yuda Prasetya Nugraha, Meutia Kamilatun Nuha Ap Idjan, and Jaidan Jauhari. "The morphology of polyvinylpyrrolidone nanofibers containing Anredera cordifolia leaves." Jurnal Ilmiah Pendidikan Fisika Al-Biruni 10, no. 2 (2021): 179–89. http://dx.doi.org/10.24042/jipfalbiruni.v10i2.8820.

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The electrospinning method has been used successfully to make polyvinylpyrrolidone nanofiber containing Anredera cordifolia leaves (BLE). The research methods used were qualitative and pure experiment method. Polyvinilpirolidone nanofibers containing BLE were prepared with three mass variations of the polyvinylpyrrolidone (% w/w), namely 12%, 10%, and 8% w/w, respectively. The results of the macroscopic photo show that the fiber structure looks white for PVP nanofibers and yellow for PVP/BLE nanofibers. The fiber morphology was analyzed using SEM and the results showed that PVP and all PVP/BLE nanofibers were like a continuous strand of crossbars with a diameter of 590 – 1190 nm. The decrease in the concentration of the PVP polymer led to a reduction in the diameter of the resulting nanofibers. The coefficients of variance (ε), of the PVP, BLE1, BLE2, and BLE3 nanofibers were 0.06, 0.09, 0.11, and 1.22, respectively. The physicochemical structure of the nanofibers was evaluated using XRD and FTIR. The chemical analysis (FTIR) showed that there was a molecular interaction between Anredera cordifolia leaves extract and polyvinylpyrrolidone in the form of hydrogen bonds. The physics analysis (XRD) shows the effect of the electrospinning process, which is to change the structure of BLE crystals to semi crystals. The application of PVP/BLE nanofiber for wounds dressing

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2

Nur, Syamsu, Rumiyati Rumiyati, and Endang Lukitaningsih. "SCREENING OF ANTIOXIDANTS, ANTI-AGING AND TYROSINASE INHIBITORY ACTIVITIES OF ETHANOLIC AND ETHYL ACETATE EXTRACTS OF FRUIT FLESH AND FRUIT PEEL LANGSAT (Lansium domesticum Corr) IN VITRO." Majalah Obat Tradisional 22, no. 1 (2017): 63. http://dx.doi.org/10.22146/tradmedj.24342.

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This study aims to determine the bioactivity of L.domesticum as cosmetic ingredient. The extraction was prepared by maceration with ethanol 96 % and ethyl acetate to obtain ethanolic extract of fruit flesh (BLE), ethanolic extract of fruit peel (KLE), ethyl acetate extract of fruit flesh (KLE) and fruit peel (KLEA). Then, determination of compounds was conducted by thin layer chromatography (TLC) and analysed of total phenolic and flavonoid content with colorimetric method. The antioxidant capacity was measured using radical scavenging assay of 1,2-diphenyl-2-picrylhydrazyl (DPPH), β-carotene bleaching assay (BCB) and ferric reducing antioxidant power assay (FRAP). The inhibitory effect of skin degradation enzymes (anti-aging) was carried out using elastase and collagenase assay. The tyrosinase inhibitory effect was determined using mushroom tyrosinase. Based on TLC result, extract of L.domesticum containing phenolic, flavonoids, terpenoids and steroids compounds. The largest of total flavonoid content was obtained in KLE (4,76±0,26 %b/b EQ) and phenolic total content in BLEA (6,4±0,15 %b/b EG). Sequence of antioxidant activity measured using DPPH method was BLEA> KLE> BLE> KLEA; while using BCB method and FRAP method were respectively KLEA>BLEA> KLE> BLE; and BLEA> KLE> BLE> KLEA. KLE and KLEA extracts showed the most potent to remaining activity of the enzyme elastase and collagenase. In addition, BLE extract has the higest tyrosinase inhibition than others. Based on these results it can be concluded that the extracts of the fruit flesh and fruit peel of L. domesticum can be used as a cosmetic active ingredient for anti-aging and anti-tyrosinase.

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3

Raj, Uttpal. "Bluetooth Low Energy: A Comprehensive Wireless Technology." International Journal of Advance Research and Innovation 9, no. 3 (2021): 64–69. http://dx.doi.org/10.51976/ijari.932110.

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BLE, Bluetooth low energy is low power wireless communication technology that is used to connect a number of devices like smartphones, smart watches, wireless speakers, fitness watches, etc. at the same instance of time. Apple was the first phone to introduce BLE into their smartphone iphone4s back in 2011 and after that most of the companies started to include BLE into their devices for a faster reliable and secure connection. The technology was made in 2010 named Bluetooth smart also Bluetooth version 4.0 and then BLE5 was introduced in 2016 and the device versions which could run BLE are windows 8 or above, android 4.0 and above, IOS 5.0 and later, Linux 3.4, and mac OS 10.10 and above.

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4

Materny-Jakubska, Aleksandra, Małgorzata Zadurska, and Justyna Poddębniak. "Bean syndrome (Blue Naevus Bleb Syndrome, BRBNS). Literature review and case report." Orthodontic Forum 20, no. 2 (2024): 112–21. https://doi.org/10.5114/for.2024.145531.

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5

Lopez Mamani, Geovana Isabel. "Perfil de resistencia antimicrobiana de Escherichia coli y Klebsiella pneumoniae en pacientes que acudieron al Hospital del Norte durante diciembre 2022 – abril 2023." Revista Científica de Salud UNITEPC 10, no. 2 (2023): 8–16. http://dx.doi.org/10.36716/unitepc.v10i2.627.

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Introducción: Las infecciones causadas por bacterias resistentes a múltiples antibióticos son un problema mundial. El objetivo de la presente investigación fue determinar el perfil de resistencia antimicrobiana de Escherichia coli y Klebsiella pneumoniae en pacientes que acudieron al Hospital del Norte, Cochabamba - Bolivia. Método: La población estuvo conformada por 134 pacientes. Se incluyeron muestras de orina, esputo, punta de catéter, aspirado traqueal, secreción vaginal, líquido abdominal, absceso, secreción faríngea y secreción escrotal, provenientes de pacientes de ambos sexos y que fueron atendidos entre los meses de diciembre 2022 – abril 2023. El aislamiento e identificación de bacterias se realizó en Agar, Sangre, Mac Conkey, Eosina Azul de Metileno (EMB), pruebas bioquímicas y determinación de resistencia y sensibilidad antibiótica in vitro utilizando el método de disco difusión en agar. Resultados: Los microorganismos que se aislaron con mayor prevalencia fue Escherichia coli con 93,3 %, seguido por Klebsiella pneumoniae con 6,7 %. Ambos microorganismos presentaron mecanismos de resistencia de tipo betalactamasas de espectro extendido (BLEE), betalactamasas de espectro ampliado (BLEA) y serin-betalactamasas (AMPc). Conclusión: La bacteria más aislada fue la Escherichia coli productora de BLEE, BLEA y AMPc, con mayor frecuencia en el sexo femenino. Presentando multirresistencia a los antibióticos cefazolina, ácido Nalidíxico, ciprofloxacina, ampicilina y gentamicina. Y K. pneumoniae presento multirresistencia a cefazolina, ciprofloxacina, ampicilina, cefotaxima y gentamicina.

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6

Emaz, Antoine. "Bleu très bleu." Po&sie N°172-173, no. 2 (2020): 9. http://dx.doi.org/10.3917/poesi.172.0009.

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7

Palmer, Jerry. "Genrer og medier - et kort overblik." MedieKultur: Journal of media and communication research 6, no. 14 (1990): 13. http://dx.doi.org/10.7146/mediekultur.v6i14.860.

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Det er vanskeligt at finde korte oversigter på dansk over fænomenet "genrer og medier". Selv i det nye opslagsværk MEDIEHÅNDBOGEN (Gyldendal 1990) leder man forgæves efter en selvstændig artikel om genre, og henvises blot artikler om "blandingsgenrer", "film" og "journa- listiske fortællerformer". Både for at dække dette hul i medie-faglittera- turen og for at forsyne de mere specifikke artikler om genreproblem- stillinger i dette nummer med et indledende rids bringer vi her Jerry Palmers lille artikel, der dels anskuer genre i et kort historisk perspek- tiv (tilbage til Platon og Aristoteles), dels opridser nogle positioner i den nyere debat. Palmer diskuterer bl.a., om det er muligt entydigt at kategorisere en tekst som tilhørende én bestemt genre, og om genretilhørsforhold skyldes iboende træk ved teksten selv, eller er afledt af kommunikationsproces- sen i dens helhed, specielt på modtagersiden? Artiklen, der blev præsen- teret ved IAMCRs konference i Bled (1990) er oversat og bearbejdet af Henning Silverbrandt.

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8

Reznik, Florence. "Bleu." Che vuoi ? 30, no. 2 (2008): 107. http://dx.doi.org/10.3917/chev.030.0107.

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9

Baumann, Michael H. "To Bleb or Not To Bleb?" Chest 132, no. 4 (2007): 1110–12. http://dx.doi.org/10.1378/chest.07-1283.

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10

Quigley, H., S. La Borwit, and H. Jampel. "SURGICAL METHODS OF BLEB REVISION AFTER TRABECULECTOMY: BLEB REDUCTION AND BLEB REPAIR." Journal of Glaucoma 9, no. 1 (2000): 105. http://dx.doi.org/10.1097/00061198-200002000-00025.

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11

La Borwit, Scott E., Harry A. Quigley, and Henry D. Jampel. "Bleb reduction and bleb repair after trabeculectomy." Ophthalmology 107, no. 4 (2000): 712–18. http://dx.doi.org/10.1016/s0161-6420(99)00174-8.

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12

Bleichrodt, Robin, and Jan Hoffenaar. "Defensiehervormingen in de jaren ’70." Tijdschrift voor geschiedenis 128, no. 3 (2015): 407–31. http://dx.doi.org/10.5117/tvgesch2015.3.blei.

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13

Blei, Karel. "De receptie van de Lima-tekst over doop, eucharistie en ambt in Nederland." NTT Journal for Theology and the Study of Religion 40, no. 1 (1986): 14–43. http://dx.doi.org/10.5117/ntt1986.40.002.blei.

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14

BLEUMINK, HANS. "Weidebevloeiing in de Brabantse Scheeken." Tijdschrift voor Historische Geografie 4, no. 1 (2019): 2–14. http://dx.doi.org/10.5117/thg2019.1.001.bleu.

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Historical surface irrigation of pastures in the Dutch province of Noord-Brabant: visible traces of a failed experiment In the second half of the 19th century, some major changes occurred in the water management of the eastern and southern provinces of the Netherlands. Unlike the low-lying western parts of the Netherlands which were characterised by polders and had a long history of formal water boards, the higher eastern and southern parts of the Netherlands were characterized by brook systems and sandy soils, and had no centralised water boards until 1850. From the 1850s onward, water boards were introduced in these higher regions as well, and agronomical scientists and organisations like the Nederlandse Heidemaatschappij endeavoured for the modernisation of agricultural water management. One of their priorities was the introduction of modern forms of surface irrigation of pastures, in order to increase crop yields. In various places modern irrigation systems were constructed. From the 1900s onward, these systems were abandoned due to the introduction of new chemical fertilizers, among others. This article describes the construction and abandonment of one of these modern irrigation systems that was located in Liempde, in the province of Noord-Brabant. The local farmers were not interested in the new technique, and within a few years the system was transformed in a poplar plantation. Nowadays, the area is part of a nature reserve. Nonetheless, the global layout of the irrigation system is still visible.

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15

Bleijenbergh, Inge. "Nederlandse kwaliteitscriteria voor kwalitatief onderzoek zijn een stap vooruit: houd ruimte voor verschillende interpretaties." KWALON 26, no. 2 (2021): 101–4. http://dx.doi.org/10.5117/kwalon2021.2.004.blei.

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16

Blei, Karel. "Ingebed in ‘de schoot der vroomheid’ : Het contemplatieve karakter van Noordmans’ theologie1." NTT Journal for Theology and the Study of Religion 73, no. 3 (2019): 235–47. http://dx.doi.org/10.5117/ntt2019.3.007.blei.

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Abstract The ‘contemplative turn’ in today’s theology had already a predecessor in the theology of O. Noordmans. That theology, developed in the first half of the 20th century, was (as Noordmans himself put it) ‘embedded’ in ‘the church as mother church’, as a ‘womb of piety’. This article describes how that can be seen in Noordmans’s appreciation of the pastoral character of Reformed dogmatics and in his sharp distinction between ‘church’ and ‘school’. The church, according to him, is not a place for doing philosophy, rather for proclaiming the Gospel, and the dogma serves only to keep the preacher on the right path. In this context, special attention is paid to Noordmans’s doctrine of creation, as summarized in his statement: ‘Creating is not forming, but dividing’. In other words: creation cannot be a (philopsophical) theme in itself; rather it is the beginning of a story: the story of the procession towards the cross.

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17

Blekendaal, Thirza. "De vele petten van Mea Verwey." Zacht Lawijd 23, no. 3 (2024): 25–41. http://dx.doi.org/10.5117/zl2024.3.004.blek.

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18

De Bleser, Frederik, Martina Menegon, and Lieven Menschaert. "I’m sorry I made you feel that way. Exploring empathy and well-being through virtual bodies and generative AI." FORUM+ 31, no. 2 (2024): 20–25. http://dx.doi.org/10.5117/forum2024.2.004.bles.

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19

Bleize, Daniëlle N. M. "Kuddegedrag op WhatsApp." Tijdschrift voor Communicatiewetenschap 51, no. 1 (2023): 70–93. http://dx.doi.org/10.5117/tcw2023.1.005.blei.

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20

Bleijenbergh, Inge. "Actieonderzoek, citizen science en participatieve methoden." KWALON 28, no. 3 (2023): 164–72. http://dx.doi.org/10.5117/kwa2023.3.002.blei.

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21

Chandran, Premanand. "Encapsulated Bleb." Ophthalmology Glaucoma 4, no. 2 (2021): 192. http://dx.doi.org/10.1016/j.ogla.2020.11.002.

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22

Ichhpujani, Parul, and Surinder Singh Pandav. "Bleb Revision." Current Journal of Glaucoma Practice with DVD 4 (September 2010): 155–57. http://dx.doi.org/10.5005/jp-journals-10008-1084.

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23

Rey, Jean-Dominique. "Bleu-vertige." Insistance 10, no. 2 (2013): 51. http://dx.doi.org/10.3917/insi.010.0051.

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24

Srivastava, RajatM, Shaurya Verma, and Siddharth Agrawal. "Misplaced bleb!" Indian Journal of Ophthalmology - Case Reports 1, no. 4 (2021): 874. http://dx.doi.org/10.4103/ijo.ijo_3530_20.

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Vavvas, Demetrios, and Katarzyna Brodowska. "Traumatic Bleb." New England Journal of Medicine 361, no. 2 (2009): e2. http://dx.doi.org/10.1056/nejmicm0802306.

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26

BAILEY, PAUL. "Disque bleu." Critical Quarterly 37, no. 3 (1995): 39–42. http://dx.doi.org/10.1111/j.1467-8705.1995.tb01070.x.

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Mannion, S. J., J. S. Mehta, and J. D. Spencer. "Oedème bleu." Journal of the Royal Society of Medicine 91, no. 9 (1998): 491–92. http://dx.doi.org/10.1177/014107689809100911.

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LOMBARDO, PATRIZIA. "Cruellement bleu." Critical Quarterly 36, no. 1 (1994): 131–33. http://dx.doi.org/10.1111/j.1467-8705.1994.tb01024.x.

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29

Fahnestock, Lee, and Anne Bragance. "Bleu Indigo." World Literature Today 61, no. 3 (1987): 416. http://dx.doi.org/10.2307/40143326.

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30

Verdier, Marie-Hélène. "Bleu noir." Pierre d'angle 5 (1999): 145–60. http://dx.doi.org/10.5840/pda1999511.

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31

Moayedi, Siamak, and Ryan Spangler. "Infected bleb." Visual Journal of Emergency Medicine 37 (October 2024): 102147. http://dx.doi.org/10.1016/j.visj.2024.102147.

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32

Dyclo-Pomos, Sylvie. "Coma bleu." Théâtre/Public N° 232, no. 2 (2019): 113. https://doi.org/10.3917/thepu.232.0113.

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Barton, Keith. "Bleb Dysesthesia." Journal of Glaucoma 12, no. 3 (2003): 281–84. http://dx.doi.org/10.1097/00061198-200306000-00018.

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34

Ipavec, Anja, and Alenka Julijana Klasinc. "Bled – Pristava." Arheološki vestnik 74 (July 14, 2023): 353–84. http://dx.doi.org/10.3986/av.74.12.

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   V obdobju od julija do decembra 2019 so na Pristavi na Bledu, na območju nekdanje obrtne cone in srednjeveške pristave, potekale arheološke raziskave v okviru gradnje muzeja sodobne umetnosti Lah Contemporary. Izkopavanja so razkrila zapleteno stratigrafsko sliko. Na podlagi natančnejše časovne opredelitve odkritih najdb in rezultatov radiokarbonskega datiranja je bilo ugotovljenih šest naselbinskih faz. Strmo pobočje hriba Pristava je bilo v pozni bronasti in starejši železni dobi terasirano. Na izravnavah je bilo postavljenih več lesenih objektov, kurišča in številne jame. V članku so predstavljene novoodkrite ostaline ter najdbe železnodobne naselbine.  

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35

Metzger, Philippe. "Bleu marine." La Géographie N° 1567, no. 4 (2017): 64–65. http://dx.doi.org/10.3917/geo.1567.0064.

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36

Moorhead, Andrea. "Silence bleu." Revue Possibles 45, no. 2 (2021): 213. http://dx.doi.org/10.62212/revuepossibles.v45i2.661.

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37

Abrahamsson, Lena. "Just när det blev viktigt blev det manligt." Tidskrift för genusvetenskap 23, no. 1 (2022): 37–52. http://dx.doi.org/10.55870/tgv.v23i1.4252.

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This article is about the dynamics of gender in workplaces that are undergoing changes in organization. More precisely it is about the instability in femininity and masculinity and the links between the construction of gender and the construction of the modern organizations. On a general level the traditional gender order is based on stability, that is to say that men and women are seen as very different, even as each other's antithesis, and with different values. This kind of gender stability works as a strong restorative mechanism in the organization of local workplaces since the resulting attempts to maintain segregation and hierarchy are directly contradictory to the modern organizational concepts that aim for integration and de-centralization. Gender order in such organizations does not only provide stability, at the same time we can also see dynamic processes at work whereby parts of the contents of the concepts masculinity and femininity are transformed. For example, social competence is often seen as a "female" characteristic or ability, but is more and more becoming a "male" competence, something that men should have as well. The construction of masculinity in local organizations is thus modified in accordance with what is important to modern organizational concepts. In other words, the dynamics of gender construction makes it possible to implement modern organization concepts without changing the gender order too much.

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38

Sugimoto, Koichiro, Kimiko Asano-Shimizu, Hiroshi Murata, Takehiro Yamashita, and Ryo Asaoka. "Bleb Plication for a Leaking Bleb After Trabeculectomy." Journal of Glaucoma 29, no. 8 (2020): e80-e82. http://dx.doi.org/10.1097/ijg.0000000000001543.

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39

Singh, Arshi, Kirti Singh, and Aastha Singh. "Bleb resuscitation of failing, leaking and dysfunctional blebs: A review." Indian Journal of Ophthalmology 73, Suppl 2 (2025): S197—S206. https://doi.org/10.4103/ijo.ijo_1233_24.

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The success of trabeculectomy surgery depends on the longevity of the filtering bleb. Bleb failure can be categorized into two types: the scarred bleb with high intraocular pressure or the over-filtering and leaking bleb with low intraocular pressure. Bleb scarring is an insidious process over time as a consequence of excessive subconjunctival fibrosis. Timely recognition and early intervention utilizing a stepped-up approach are important for resuscitating the bleb and salvaging the trabeculectomy. Over-filtration and leaky bleb on the other end of the spectrum lead to failure of optimal bleb function and require a different management approach. This review discusses in detail various surgical techniques to revive dysfunctional blebs with a special focus on bleb needling. Timely identification and multifaceted management of bleb-related complications is the key to ultimately improving long-term success rates and patient outcomes.

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40

Satoh, Toru. "Hemodynamic analysis of a thrombosed bleb in an unruptured cerebral aneurysm." Surgical Neurology International 15 (October 4, 2024): 357. http://dx.doi.org/10.25259/sni_584_2024.

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Background: The intricate hemodynamic mechanisms of thrombosis in the bleb and/or dome of cerebral aneurysms remain unresolved. We encountered a unique case where the bleb of an unruptured internal carotid-posterior communicating artery (IC-PC) aneurysm underwent thrombosis over 7 years. Complete spontaneous thrombosis of a bleb in an unruptured cerebral aneurysm has not been previously reported. Therefore, a hemodynamic evaluation using computational fluid dynamics (CFD) analysis was conducted to examine the thrombotic development within the bleb of this aneurysm. Case Description: We observed a case in which thrombosis led to the disappearance of a bleb in the dome of an unruptured IC-PC aneurysm over 7 years. CFD analysis was employed to investigate the hemodynamics of bleb thrombosis and the thrombosed bleb-neck regions of the dome in this IC-PC aneurysm. The reduction and disappearance of the bleb were associated with a decreased flow rate within the bleb, reduced magnitude of wall shear stress (WSSm), a lower WSSm ratio between the bleb and dome, increased vector direction of wall shear stress (WSSv), and discrete streamlines entering the bleb-neck region, resulting in stasis and subsequent thrombosis within the bleb. Seven years later, the dome region corresponding to the thrombosed bleb-neck exhibited localized areas with low WSSm and high WSSv along the dome wall. Conclusion: Hemodynamically, spontaneously thrombosed bleb and thrombosed post-bleb-neck dome walls were characterized by low WSSm and high WSSv. These findings underscore the importance of CFD analysis in predicting thrombotic events in cerebral aneurysms, which can inform better clinical management strategies.

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41

Hayat, Mohammed R., Fatema S. Mollah, and Kamal Kishore. "Intracameral Air and Fibrin Glue for the Management of Late Bleb Leak following Glaucoma Surgery." Case Reports in Ophthalmology 10, no. 1 (2019): 47–52. http://dx.doi.org/10.1159/000496383.

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Background and Objectives: To report a case of delayed-onset bleb-associated endophthalmitis (BAE) with bleb leak successfully managed with pars plana vitrectomy, intravitreal antibiotics, intracameral air, and fibrin glue. Patient and Methods: A 66-year-old pseudophakic female presented with BAE and bleb leak. A 25-gauge pars plana vitrectomy, cultures, and intravitreal antibiotics and steroid injections were performed. The infusion was switched to air filling the anterior chamber and bleb with air. Fibrin glue (Tisseel®) was applied over the leaking bleb. Results: BAE and bleb leak resolved with return of visual acuity to 20/25 and a functioning bleb with no recurrence of bleb leak after 1 year of follow-up. Conclusion: The combination of intracameral air and fibrin glue may have a role in the management of bleb leaks.

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42

Rachma, Adessa, and Maula Rifada. "Cystic Bleb Management : A Case Report." MAHESA : Malahayati Health Student Journal 4, no. 3 (2024): 1114–22. http://dx.doi.org/10.33024/mahesa.v4i3.14063.

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ABSTRACT Cystic Bleb Is An Abnormal Bleb Morphology Following Trabeculectomy Procedure. This Type Of Bleb Characterized By An Elevated, Thin, And Avascular Bleb Surface. Post-Operative Bleb Evaluation Needed To Be Done Thoroughly To Recognize And Prevent Further Complication Which Can Be Sight Threatening. Several Options Of Management Include Medical Therapy And Surgical Repair. To Report The Management Of Cystic Bleb. The Study Design Is A Case Report Study, Which Was Conducted At Indonesia National Eye Centre, Cicendo Eye Hospital, Bandung, Indonesia. Subject Of The Study Was A-17-Years-Old Female That Presented With Discomfort Sensation In The Right Eye, Which Previously Has Undergone Trabeculectomy Procedure With Antifibrotic Agent Application. Ophthalmological Examination Revealed A Cystic Bleb On The Right Eye. After Medical Therapy Was Given, The Symptoms Persist, Then The Cystic Bleb Was Surgically Repaired. Follow-Up Examination Showed An Improvement Of The Patient’s Condition, Measured By No Further Complaint Of Discomfort Sensation, A Good Bleb Morphology, And A Stable Intraocular Pressure. Cystic Bleb Is One Of The Complication From Trabeculectomy Which Could Progress To Devastating Condition. Surgical Treatment Is Indicated If Symptoms Persist After Medical Management, Or In The Presence Of A Bleb Leakage. Keywords: Antifibrotic, Cystic Bleb, Trabeculectomy

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Chao, Tze-Fan, Yenn-Jiang Lin, Shih-Lin Chang, et al. "Incident Risk Factors and Major Bleeding in Patients with Atrial Fibrillation Treated with Oral Anticoagulants: A Comparison of Baseline, Follow-up and Delta HAS-BLED Scores with an Approach Focused on Modifiable Bleeding Risk Factors." Thrombosis and Haemostasis 47, no. 04 (2018): 768–77. http://dx.doi.org/10.1055/s-0038-1636534.

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Aim When assessing bleeding risk in patients with atrial fibrillation (AF), risk stratification is often based on the baseline risks. We aimed to investigate changes in bleeding risk factors and alterations in the HAS-BLED score in AF patients. We hypothesized that a follow-up HAS-BLED score and the ‘delta HAS-BLED score’ (reflecting the change in score between baseline and follow-up) would be more predictive of major bleeding, when compared with baseline HAS-BLED score. Methods and Results A total of 19,566 AF patients receiving warfarin and baseline HAS-BLED score ≤2 were studied. After a follow-up of 93,783 person-years, 3,032 major bleeds were observed. The accuracies of baseline, follow-up, and delta HAS-BLED scores as well as cumulative numbers of baseline modifiable bleeding risk factors, in predicting subsequent major bleeding, were analysed and compared. The mean baseline HAS-BLED score was 1.43 which increased to 2.45 with a mean ‘delta HAS-BLED score’ of 1.03. The HAS-BLED score remained unchanged in 38.2% of patients. Of those patients experiencing major bleeding, 76.6% had a ‘delta HAS-BLED’ score ≥1, compared with only 59.0% in patients without major bleeding (p < 0.001). For prediction of major bleeding, AUC was significantly higher for the follow-up HAS-BLED (0.63) or delta HAS-BLED (0.62) scores, compared with baseline HAS-BLED score (0.54). The number of baseline modifiable risk factors was non-significantly predictive of major bleeding (AUC = 0.49). Conclusion In this ‘real-world’ nationwide AF cohort, follow-up HAS-BLED or ‘delta HAS-BLED score’ was more predictive of major bleeding compared with baseline HAS-BLED or the simple determination of ‘modifiable bleeding risk factors’. Bleeding risk in AF is a dynamic process and use of the HAS-BLED score should be to ‘flag up’ patients potentially at risk for more regular review and follow-up, and to address the modifiable bleeding risk factors during follow-up visits.

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Paulaviciute-Baikstiene, Daiva, Renata Vaiciuliene, and Ingrida Januleviciene. "Filtering blebs structure and function evaluation using optical coherence tomography." Modeling and Artificial Intelligence in Ophthalmology 1, no. 2 (2016): 10–19. http://dx.doi.org/10.35119/maio.v1i2.15.

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Purpose: To assess the ability of a noncontact optical coherence tomography to evaluate the morphological features of filtering blebs one year after glaucoma surgery.Design: Prospective study.Methods: Eighteen patients (18 eyes) with diagnosed primary open-angle glaucoma (POAG) assigned for trabeculectomy were included in the 12-month study carried out in the Eye clinic of the Lithuanian University of Health Sciences. All participants underwent trabeculectomy with 5-fluorouracil (5-FU). Bleb function was considered to be successful if the intraocular pressure (IOP) was ≤ 18 mmHg without glaucoma medications and a limited success if: 18 < IOP ≤ 21 mmHg with or without glaucoma medications at 12 months after surgery. The filtering blebs were imaged by anterior segment optical coherence tomography (AS-OCT) to evaluate the bleb wall reflectivity and measured bleb structures 12 months after trabeculectomy. Level of significance: p < 0.05 was considered significant.Results: The mean preoperative IOP was 25.7 (6.5) mmHg and the mean number of topical glaucoma medications was 3.0 (1.2). After surgery the mean IOP was 13.8 (3.4) mmHg and glaucoma medication was 0.3 (1.0) (Wilcoxon test, p < 0.001). Analyzing bleb morphology and bleb function it was found that with uniform wall reflectivity 0 out of 3 eyes (0%) had successful bleb function and with multiform wall reflectivity 14 out of 15 eyes (93.3%) had successful bleb function 12 months after surgery (p = 0.005).We found positive correlation between IOP changes and bleb wall thickness, height of internal fluid-filled cavity (bleb height) and total bleb height (r = 0.875, 0.897, 0.939, p < 0.001).Conclusion: AS-OCT is a useful device to assess the structure of the filtering bleb. Larger internal fluid-filled cavity, total bleb height, bigger bleb wall thickness and multiform bleb wall reflectivity were found to be good indicators of bleb function.

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Taneja, Nilay, and Dylan T. Burnette. "Myosin IIA drives membrane bleb retraction." Molecular Biology of the Cell 30, no. 9 (2019): 1051–59. http://dx.doi.org/10.1091/mbc.e18-11-0752.

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Membrane blebs are specialized cellular protrusions that play diverse roles in processes such as cell division and cell migration. Blebbing can be divided into three distinct phases: bleb nucleation, bleb growth, and bleb retraction. Following nucleation and bleb growth, the actin cortex, comprising actin, cross-linking proteins, and nonmuscle myosin II (MII), begins to reassemble on the membrane. MII then drives the final phase, bleb retraction, which results in reintegration of the bleb into the cellular cortex. There are three MII paralogues with distinct biophysical properties expressed in mammalian cells: MIIA, MIIB, and MIIC. Here we show that MIIA specifically drives bleb retraction during cytokinesis. The motor domain and regulation of the nonhelical tailpiece of MIIA both contribute to its ability to drive bleb retraction. These experiments have also revealed a relationship between faster turnover of MIIA at the cortex and its ability to drive bleb retraction.

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Kahook, Malik Y., Joel S. Schuman, and Robert J. Noecker. "Needle Bleb Revision of Encapsulated Filtering Bleb With Bevacizumab." Ophthalmic Surgery, Lasers and Imaging Retina 37, no. 2 (2006): 148–50. http://dx.doi.org/10.3928/1542-8877-20060301-12.

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Sawada, Akira, Yasuaki Kuwayama, and Tetsuya Yamamoto. "Changes in filtering bleb morphology after bleb-related infection." Japanese Journal of Ophthalmology 59, no. 5 (2015): 312–17. http://dx.doi.org/10.1007/s10384-015-0398-9.

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Priyambudi, Hasif, and Arifiyanto Hadinegoro. "PERFORMANCE ANALYSIS RESNET50 AND INCEPTIONV3 MODELS FOR CAPTION IMAGE GENERATOR." JURTEKSI (Jurnal Teknologi dan Sistem Informasi) 9, no. 3 (2023): 521–28. http://dx.doi.org/10.33330/jurteksi.v9i3.2277.

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Abstract: Generating caption image automatically is one of the challenges in computer vision. This field can be very helpful in many ways, for example search engines. Currently there are many image classification algorithms that we can use to create a caption image model. In this article, we will compare performance between the Resnet50 and InceptionV3 models for text images. We will use 2000 (1800 train & 200 validation) image data and each image has 5 example captions to train the model. After the model is successfully created, we evaluate the model using 100 images and each image has 5 examples of additional captions that are not used in the training and validation process. The result of this research is that the InceptionV3 model is better than Resnet50. BLEU-1 is 0.53, BLEU-2 is 0.35, BLEU-3 is 0.18, BLEU-4 is 0.09, and METEOR is 0.35 for InceptionV3 model. While Resnet50 model has a value of BLEU-1 is 0.51, BLEU-2 is 0.31, BLEU-3 is 0.16, BLEU-4 is 0.06, and METEOR is 0.33. Keywords: caption image; inceptionv3; LSTM; resnet50 Abstrak: Membuat gambar teks secara otomatis adalah salah satu tantangan dalam computer vision. Bidang ini bisa sangat membantu dalam banyak hal, misalnya mesin pencari. Saat ini banyak sekali algoritma klasifikasi citra yang dapat kita gunakan untuk membuat model teks citra. Pada artikel ini, kami akan membandingkan performa antara model Resnet50 dan InceptionV3 untuk gambar teks. Kami akan menggunakan 2000 (1800 train & 200 validation) data gambar dan setiap gambar memiliki 5 contoh caption untuk melatih model. Setelah model berhasil dibuat, kami mengevaluasi model menggunakan 100 gambar dan setiap gambar memiliki 5 contoh caption tambahan yang tidak digunakan dalam proses training dan validation. Hasil dari penelitian ini adalah model InceptionV3 lebih baik dibandingkan dengan Resnet50. BLEU-1 0.53, BLEU-2 0.35, BLEU-3 0.18, BLEU-4 0.09, dan METEOR 0.35 untuk model InceptionV3. Sedangkan model Resnet50 memiliki nilai BLEU-1 0.51, BLEU-2 0.31, BLEU-3 0.16, BLEU-4 0.06, dan METEOR 0.33. Kata kunci: caption image; inceptionv3; LSTM; resnet50

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Khafagy, Amr, and Hany Elmekawey. "Management of Bleb Failure with 5-Fluorouracil Augmented Bleb Needling and Sub-Bleb Healon-5 Injection." Highlights of Ophthalmology 40, no. 6ENG (2012): 8–12. http://dx.doi.org/10.5005/hoo-10101-40602.

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Jiao, Meng, Di Wu, and Qize Wei. "Myosin II–interacting guanine nucleotide exchange factor promotes bleb retraction via stimulating cortex reassembly at the bleb membrane." Molecular Biology of the Cell 29, no. 5 (2018): 643–56. http://dx.doi.org/10.1091/mbc.e17-10-0579.

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Blebs are involved in various biological processes such as cell migration, cytokinesis, and apoptosis. While the expansion of blebs is largely an intracellular pressure-driven process, the retraction of blebs is believed to be driven by RhoA activation that leads to the reassembly of the actomyosin cortex at the bleb membrane. However, it is still poorly understood how RhoA is activated at the bleb membrane. Here, we provide evidence demonstrating that myosin II–interacting guanine nucleotide exchange factor (MYOGEF) is implicated in bleb retraction via stimulating RhoA activation and the reassembly of an actomyosin network at the bleb membrane during bleb retraction. Interaction of MYOGEF with ezrin, a well-known regulator of bleb retraction, is required for MYOGEF localization to retracting blebs. Notably, knockout of MYOGEF or ezrin not only disrupts RhoA activation at the bleb membrane, but also interferes with nonmuscle myosin II localization and activation, as well as actin polymerization in retracting blebs. Importantly, MYOGEF knockout slows down bleb retraction. We propose that ezrin interacts with MYOGEF and recruits it to retracting blebs, where MYOGEF activates RhoA and promotes the reassembly of the cortical actomyosin network at the bleb membrane, thus contributing to the regulation of bleb retraction.

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