Relevant bibliographies by topics / Bleeding canker

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  2. Dissertations / Theses
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Academic literature on the topic 'Bleeding canker'

Author: Grafiati
Published: 10 March 2023

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Journal articles on the topic "Bleeding canker"

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Nelson, A. H., and G. W. Hudler. "A Summary of North American Hardwood Tree Diseases with Bleeding Canker Symptoms." Arboriculture & Urban Forestry 33, no. 2 (March 1, 2007): 122–31. http://dx.doi.org/10.48044/jauf.2007.013.

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Although the presence of bleeding cankers on deciduous trees may raise fears of the presence of Phytophthora ramorum, the cause of sudden oak death, other pathogens also cause similar symptoms. This review of hardwood tree diseases with bleeding canker symptoms provides an overview of available information of these diseases, providing a diagnosis guide as well as a stimulus for continued research in these areas.
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Weiland, Jerry E., Angela H. Nelson, and George W. Hudler. "Aggressiveness of Phytophthora cactorum, P. citricola I, and P. plurivora from European Beech." Plant Disease 94, no. 8 (August 2010): 1009–14. http://dx.doi.org/10.1094/pdis-94-8-1009.

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Phytophthora cactorum, P. citricola I, and P. plurivora cause bleeding cankers on mature European beech (Fagus sylvatica) trees in the northeastern United States. Inoculation experiments were conducted to compare the aggressiveness of the three Phytophthora spp. on stems, leaf disks, and roots of European beech and common lilac (Syringa vulgaris) seedlings. Isolates were obtained from bleeding cankers on European beech from five cities in New York (Albany, Ithaca, Oyster Bay, Plainview, and Rochester) and from a bleeding canker on sugar maple in Ithaca, NY. Stems were inoculated with colonized agar plugs, leaf disks with a zoospore suspension, and roots via infested soil at three inoculum levels. All organs of inoculated beech and lilac developed disease except for lilac roots inoculated with zoospores of P. cactorum. Disease incidence, severity, and plant survival were dependent on isolate and were also influenced by the tissue inoculated and host. Isolates of P. cactorum were the least aggressive and caused less necrosis than isolates of P. citricola I and P. plurivora. Results emphasize the utility of stem and root inoculation for evaluation of this canker disease and underscore critical differences in species aggressiveness.
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CHEN, Gong-you. "Bleeding canker of pear — An emerging devastating disease." Journal of Integrative Agriculture 19, no. 4 (April 2020): 887–88. http://dx.doi.org/10.1016/s2095-3119(20)63173-2.

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Kenaley, Shawn C., Clifford Rose, Patrick J. Sullivan, and George W. Hudler. "Bleeding Canker of European Beech in Southeastern New York State: Phytophthora Species, Spatial Analysis of Disease, and Periodic Growth of Affected Trees." Journal of Environmental Horticulture 32, no. 3 (September 1, 2014): 113–25. http://dx.doi.org/10.24266/0738-2898.32.3.113.

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The epidemiology of bleeding canker, a Phytophthora-associated disease, on European beech remains unclear. Pathogen surveys as well as dendrological and spatial point pattern analyses (SPPA) were conducted to identify factors contributing to disease progress on beech at the Green-Wood Cemetery (GWC) and Planting Fields Arboretum (PFA) in southeastern New York State. Phytophthora pini was the predominant Phytophthora isolated from cankers as well as soil under asymptomatic and diseased (canker bearing) European beech at each site. No significant differences existed between asymptomatic and Phytophthora-infected trees according to diameter breast height, elevation, and the Phytophthora spp. The radial growth (25-yr chronology for 1986 to 2010) of infected European beech at GWC and PFA, however, was significantly less when compared to asymptomatic beech; yet, residual growth was similar among the latter cohorts, providing no evidence for the instigatory effect(s) of environmental stressors on disease progress. SPPA demonstrated all beech at GWC and PFA were planted in non-random aggregates, whereas the distribution of diseased European beech did not deviate from random. Collectively, results indicated bleeding canker is a slow, chronic disease and the overland tree-to-tree spread of P. pini, and accompanying Phytophthora spp., is rare or does not occur at GWC or PFA.
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Álvarez, L. A., A. Pérez-Sierra, J. García-Jiménez, and J. Javier-Alva. "Bleeding Canker on Mesquite in Peru caused by Phytophthora syringae." Plant Disease 91, no. 2 (February 2007): 226. http://dx.doi.org/10.1094/pdis-91-2-0226a.

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Mesquite (Prosopis pallida (Wildenow) Kunth) is a drought-tolerant tree widely distributed in the northern Pacific Coast of South America. This species prevents soil erosion, provides shade, conserves prairies, supports bee nutrition, and provides fruits for human and animal consumption. Since the spring of 2004, bark lesions and bleeding cankers were observed on trunks and branches of 70% of declining mesquite trees in some parks at Ica in southern Peru. Badly affected trees were killed by the disease. Isolations were made from the edge of necrotic lesions of the inner bark and roots using PARPH medium (2) and incubated at 22°C for 7 days. A Phytophthora species was consistently isolated from lesions of 10 mesquite trees, and six pure cultures (PS-87-PS-92) were obtained by transferring hyphal tips and characterized. Colonies were stellate on V8 juice agar (VJA; 2 g CaCO3, 200 ml of V8 juice, and 15 g of agar in 800 ml of distilled water), uniform to slightly radiate on corn meal agar (Oxoid Ltd., London, England), and knotty on PDA (Biokar Diagnostics, Beauvais, France). On VJA at 22°C, the average radial growth rate for the six isolates was 1.7 mm per day. Colonies grew slowly at 5 and 25°C with 0.4 and 0.7 mm per day growth rate, respectively. There was no growth at 30°C. Catenulate hyphal swellings formed on VJA and liquid media (1.5% sterile soil extract). Sporangia were persistent, ovoid to obpyriform, semipapillate with narrow exit pores (<5.0 μm in diameter), 32.3 to 39.7 × 21.0 to 27.2 μm, with a length/width ratio of 1.4:1 to 1.6:1. Sporangia were produced by cutting 5-mm disks from the advancing margin of a colony on VJA and adding disks to 10 ml of 1.5% sterile soil extract for 4 to 5 days at 22°C under fluorescent light. Isolates were homothallic with spherical oogonia, 32 to 35 μm in width with paragynous antheridia, and aplerotic oospores, 26 to 31 μm. These characteristics fit the descriptions of Phytophthora syringae (Kleb.) Kleb. (1). Sequences of the internal transcribed spacer regions on the isolates and comparison with other sequences in GenBank showed that they were identical to P. syringae (Accession No. AJ854297 from Citrus limon). In 2005, two methods were used to inoculate mesquite with two isolates. One method used two 20-mm-diameter branches of five 5-year-old mesquite trees where a 5-mm wound was made with a cork borer and a 5-mm block of the agar culture was placed under the bark and sealed with Parafilm. Another method used 10 4-month-old potted plants that received a 30-ml drench of a 104 zoospores/ml suspension per plant. Controls received clean agar blocks and a sterile water drench for 10 control pots. Two weeks after inoculation, black areas and resinosis were observed around inoculated wounds. Inoculated branches produced cankers of 4.7 to 6.8 cm2, 4 weeks after inoculations. Twenty days after inoculation of roots, wilting and root rots of seedlings occurred. No symptoms were found on the control plants. P. syringae was reisolated from the diseased branches and root rots and pure cultures were established. This test was repeated for both methods with similar results. To our knowledge, this is the first report of P. syringae in Peru and the first description of this pathogen on mesquite worldwide. References: (1) D. C. Erwin and O. K. Ribeiro. Phytophthora Diseases Worldwide. The American Phytopathological Society, St. Paul MN. 1996. (2) S. N. Jeffers and S. B. Martin. Plant Dis. 70:1038, 1986.
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Weiland, Jerry E., Angela H. Nelson, and George W. Hudler. "Effects of Mefenoxam, Phosphonate, and Paclobutrazol on In Vitro Characteristics of Phytophthora cactorum and P. citricola and on Canker Size of European Beech." Plant Disease 93, no. 7 (July 2009): 741–46. http://dx.doi.org/10.1094/pdis-93-7-0741.

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Phytophthora citricola and P. cactorum cause bleeding cankers that lead to the death of mature European beech (Fagus sylvatica) in the northeastern United States. The effects of two fungicides and a plant growth regulator on in vitro pathogen characteristics and on canker expansion were investigated. In the first experiment, 16 single-spore isolates (11 P. citricola and 5 P. cactorum) were grown on clarified V8 juice agar amended with (i) 0 to 20 μg a.i./ml of mefenoxam, (ii) 0 to 301,429 μg a.i./ml phosphonate either with or without a bark-penetrating surfactant at 0.5 mg a.i./ml, or (iii) 0 to 25 mg a.i./ml of the surfactant alone. Radial growth, oospore production, and zoospore germination were observed to be dependent on isolate and treatment. A species effect on growth was also observed, as P. cactorum isolates were 2.5- to sevenfold less sensitive to phosphonate, but 2- to 150-fold more sensitive to mefenoxam than P. citricola isolates (based on 50% inhibition of growth). In the second experiment, bark and soil drenches of mefenoxam (50 mg a.i./ml and 19 μg a.i./ml, respectively), phosphonate (301,429 and 101 μg a.i./ml, respectively), and a soil drench of paclobutrazol (21 mg a.i./ml) were evaluated for their efficacy as curative or preventive treatments against bleeding canker. None of the treatments (curative or preventive) were able to stop canker expansion or prevent infection. However, saplings inoculated with P. citricola and treated with the phosphonate bark drench as either a curative or preventive treatment had cankers that were 36 to 82% shorter than those of inoculated control stems treated with water. For saplings inoculated with P. cactorum, the phosphonate bark drench was only effective when applied as a preventive (38% shorter than inoculated control stems treated with water), and not as a curative treatment. No other treatment was effective at limiting canker expansion.
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Majeed, Muhammed, Shaheen Majeed, and Kalyanam Nagabhushanam. "Efficacy and Safety of Tetrahydrocurcuminoids for the Treatment of Canker Sore and Gingivitis." Evidence-Based Complementary and Alternative Medicine 2020 (December 16, 2020): 1–10. http://dx.doi.org/10.1155/2020/6611877.

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Background. Tetrahydrocurcuminoids (THCs) are among the major metabolites of curcuminoids with a higher bioavailability and physiological stability and exhibit a broad spectrum of therapeutic activities. The objective of this study was to evaluate the efficacy of THCs in patients suffering from canker sore and gingivitis designed as an exploratory clinical trial. Methods. This is an open label prospective pilot clinical trial carried out at two clinical centers: Noble Hospital, Pune, Maharashtra, and Sri Venkateshwara Hospital, Bangalore, Karnataka in India. Participants were assigned to 21 days of treatment with chewable oral THCs supplement. Patients were instructed to self-administer one chewable tablet containing 100 mg of THCs twice daily for up to 21 days. This clinical trial was registered at a public Clinical Trial Registry in India (http://www.ctri.nic.in). Thirty-one canker sore and twenty-nine gingivitis patients participated in this study. Body mass index, throat numbness/relief, Visual Analog Scale (VAS) pain score, canker sore lesions, gingival appearance, inflammation and bleeding were assessed before and after treatment, at 14 and 21 days. Vital signs and laboratory parameters were assessed for safety. Results. THCs treatment significantly reduced the reddening at the site, difficulty in chewing, swallowing, and VAS pain score in the canker sore patients. Further, both single and multiple lesions were completely healed. In gingivitis patients, gingival appearance, bleeding, and inflammation were significantly reduced. No adverse effects were observed during the study. Conclusion. Overall, the findings of this study show that supplementation of THCs for 21 days reduced the pain and prevented the progression of the disease in patients suffering from canker sore and gingivitis without adverse side effects.
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Nelson, Angela H., Jerry E. Weiland, and George W. Hudler. "Prevalence, Distribution and Identification of Phytophthora Species from Bleeding Canker on European Beech." Journal of Environmental Horticulture 28, no. 3 (September 1, 2010): 150–58. http://dx.doi.org/10.24266/0738-2898-28.3.150.

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Abstract While bleeding canker of European beech trees (Fagus sylvatica) has long been recognized as a problem in Europe and North America, the cause in the northeastern United States has not been clear. To resolve this, we surveyed for disease prevalence on European beech, identified the pathogens involved, proved their pathogenicity, compared protocols for pathogen detection, and conducted a soil assay to determine pathogen presence in soil surrounding established trees in residential and commercial landscapes in New York, Pennsylvania, Maryland, Connecticut and Massachusetts. Approximately 40% of surveyed trees had bleeding cankers. While Phytophthora cactorum, P. gonapodyides, P. cambivora and two newly described species, P. citricola I and P. plurivora, were recovered from symptomatic tissue, P. citricola I and P. cactorum were most prevalent. All caused disease when artificially inoculated into European beech sapling stems, although P. cambivora and P. gonapodyides produced significantly smaller lesions. Recovery of the pathogen from symptomatic tissue using selective media, the preferred method of diagnosis, was significantly higher in the fall. ELISA detection was more successful and worked regardless of season, but did not allow identification to the species level. All five Phytophthora species were found in soil surveys; P. cambivora was most common, followed by P. cactorum and P. citricola I. These results provide a foundation for building management strategies to protect valuable specimens of European beech.
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Schmidt, O., D. Dujesiefken, H. Stobbe, U. Moreth, R. Kehr, and Th Schröder. "Pseudomonas syringae pv. aesculi associated with horse chestnut bleeding canker in Germany." Forest Pathology 38, no. 2 (April 2008): 124–28. http://dx.doi.org/10.1111/j.1439-0329.2007.00539.x.

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CHEN, Bin, Yan-li TIAN, Yu-qiang ZHAO, Jia-nan WANG, Zhi-gang XU, Xiang LI, and Bai-shi HU. "Bleeding canker of pears caused by Dickeya fangzhongdai: Symptoms, etiology and biology." Journal of Integrative Agriculture 19, no. 4 (April 2020): 889–97. http://dx.doi.org/10.1016/s2095-3119(19)62882-0.

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Dissertations / Theses on the topic "Bleeding canker"

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Britton, J. Philip. "A community study of bladder cancer screening by detection of occult urinary bleeding." Thesis, University of Bristol, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283841.

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Ogbodo, A. K., and O. P. Onwughara. "Efficiency of surgical treatment in patients with cancer of stomach, complicated with bleedeing in Nigeria." Thesis, Sumy State University, 2017. http://essuir.sumdu.edu.ua/handle/123456789/58360.

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Gastric cancer (GC) is the second leading cause of cancer death in the world. GC more frequently accompanied by bleeding signaling an advanced development from the mucosa to different layers of stomach. Bleeding may result from ulcerated mucosa, local vessel damage in 60%–70% of patients with advanced cancer. Hemorrhage may occur as an acute catastrophic event, episodic major bleeds, or ongoing low-volume oozing.
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Шевченко, Володимир Порфирович, Владимир Порфирьевич Шевченко, Volodymyr Porfyrovych Shevchenko, and М. А. Болотна. "Хірургічна тактика у хворих на рак шлунка, ускладнений кровотечею." Thesis, Вид-во СумДУ, 2007. http://essuir.sumdu.edu.ua/handle/123456789/5032.

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Inokuchi, Haruo. "Clinical effect of multileaf collimator width on the incidence of late rectal bleeding after high-dose intensity-modulated radiotherapy for localized prostate carcinoma." Kyoto University, 2016. http://hdl.handle.net/2433/215942.

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Högberg, Cecilia. "Diagnosing colorectal cancer in primary care : the value of symptoms, faecal immunochemical tests, faecal calprotectin and anaemia." Doctoral thesis, Umeå universitet, Allmänmedicin, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-133628.

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Background: Colorectal cancer (CRC) is the third most common cancer in men and the second most common in women worldwide. Adenomas can be precursors to CRC, and inflammatory bowel disease (IBD) can present with the same symptoms as CRC. The majority of patients with CRC initially consult primary care. Symptoms associated with CRC are also common among primary care patients, but seldom caused by any significant disease. Reliable diagnostic aids would be helpful in deciding which patients to refer. Faecal immunochemical tests (FITs) are commonly used for this purpose in primary care in Sweden, but there is little evidence to support this use. Faecal calprotectin (FC) has been suggested as an additional test. Aim: To explore how doctors in primary care investigate patients with suspected CRC, the value of FITs, symptoms and presence of anaemia in diagnosing CRC and adenomas in primary care, and whether FC tests could contribute to diagnosis. Methods: Three studies (1-3) were carried out in Region Jämtland Härjedalen, Sweden. There was no screening programme for CRC. We used a point of care qualitative dip-stick 3-sample FIT with a cut-off of 25-50μg haemoglobin/g faeces, and a calprotectin enzyme-linked immunosorbent assay (ELISA) test with a cut-off of 100 μg/g faeces. 1: A retrospective, population-based study including all patients diagnosed with CRC or adenomas with high-grade dysplasia (HGD) during the period 2005-2009 that initially consulted primary care. Symptoms, FIT results, anaemia and time to diagnosis were retrieved from medical records. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated from FIT results at the region’s health centres 2008- 2009. (Paper I.) 2: A prospective cohort study including consecutive patients where primary care doctors requested FITs and/or FC tests, at four health centres, from 30 Jan 2013 to 31 May 2014. FITs, FC tests, haemoglobin and iron deficiency tests were analysed; patients and doctors answered questionnaires about symptoms. Patients were examined with bowel imaging or followed for two years. Findings of CRC, adenomas with HGD, adenomas with low grade dysplasia (LGD) ≥1 cm and IBD were registered. (Papers II and III.) 3: A qualitative study of interviews with eleven primary care doctors. We explored what made them suspect CRC, and their practices regarding investigation and referral with particular attention to their use of FITs. Qualitative content analysis with an inductive approach was used for the analysis. (Paper IV.) Results: 1: Paper I: Of 495 patients 323 (65.3%) started the investigation in primary care. FITs were analysed in 215. In 23 cases with CRC, FITs were negative; 15 (65.2%) had anaemia. In 33 cases with CRC, FITs were performed due to asymptomatic anaemia; 10 (30.3%) had negative FITs. The time from start of investigation, to the diagnosis of CRC or adenomas with HGD, was significantly longer for patients with negative FITs. 2: 377 patients (9 diagnosed with CRC, 10 with IBD) were included. Paper II: Concordance of positive answers about symptoms from patients and doctors was generally low. Rectal bleeding (recorded by 43.5% of patients and 25.6% of doctors) was the only symptom related to CRC and IBD. The FIT showed a better PPV than rectal bleeding for CRC and IBD. When patients recorded rectal bleeding, the FIT had a PPV of 22.6% and a NPV of 98.9% for CRC and IBD. Paper III: The best test for detecting CRC and IBD was the combination of a positive FIT and/or anaemia with a sensitivity, specificity, PPV and NPV of 100%, 61.7%, 11.7% and 100% respectively. The FC test had no additional value to the FIT alone. The sensitivity, specificity, PPV and NPV of the FIT for CRC in study 1 was estimated at 88.4%, 73.3%, 6.2% and 99.7% respectively. In study 2, corresponding figures were 88.9%, 67.4%, 6.3% and 99.6% respectively. 3: Paper IV: We identified four categories: “Careful listening – with awareness of the pit-falls”, “tests can help – the FIT can also complicate the diagnosis”, “to refer or not to refer – safety margins are necessary”, and “growing more confident – but also more humble”. All doctors had found their own way to handle FIT results in the absence of guidelines. Conclusion: The diagnostic process when suspecting CRC can be described as navigating uncertain waters with safety margins. FITs were often used by primary care doctors but with considerable variations in interpretation and handling of results. Rectal bleeding was the only symptom related to CRC and IBD, but the FIT showed a better PPV than rectal bleeding. The combination of a negative FIT and no anaemia may be useful as a rule-out test when CRC is suspected in primary care, and this potentially also applies when patients present with rectal bleeding. Further studies are needed to confirm this and to determine the optimal FIT cut-off value for this use.
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GINETTI, BEATRICE. "Identity, impact and role of Phytophthora species in planted forests of north Italy." Doctoral thesis, 2013. http://hdl.handle.net/2158/896319.

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Hanna, FMB. "Impact of translational medical research on haematology practice." Thesis, 2021. https://eprints.utas.edu.au/46064/1/Hanna_whole%20thesis_ex_pub_mat.pdf.

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Translational Medical Research (TMR) is a relatively new research field that aims to bridge the gap between evidence-based guidelines and clinical practice. More TMR is warranted in the field of haemostatic disorders, considering limitations for easy to follow guidelines on predicting and managing venous thromboembolism (VTE). There is a gap between evidence-based guidelines and clinical practice in VTE risk prediction, prevention, or management, leading to high morbidity and mortality rates worldwide and in Australia. This thesis includes three studies that evaluate current practice against evidence-based guidelines in the field of haemostatic disorders aimed to reveal gaps in practice and provided recommendations. Study 1 presents a multicentre randomised controlled trial (RCT), which enrolled 750 participants in equal arm, parallel groups, aimed to evaluate a new protocol for VTE prevention following total hip replacement (THR) and total knee replacement (TKR) with assessment of major bleeding risk. I addressed the need to optimize VTE prophylaxis and reduce bleeding risk to improve patient safety. The newly developed and tested protocol employed a 24-hours’ intermittent pneumatic calf compression followed by Rivaroxaban (direct oral anticoagulants-DOACs) versus the currently preferred subcutaneous Enoxaparin for 14 days in TKR or 35 days in THR. There were no differences in VTE risk while Rivaroxaban showed a small significant reduction in computed major bleeding risk. Study 2 presents retrospective cross-sectional data collected to outline the characteristics and management of patients presented with bleeding at a regional Australian hospital’s emergency department while receiving anti-thrombotic therapy. Among the included 144 patients, I found that the numbers of warfarinised patients dominated when compared with the numbers of patients who received other anti-thrombotic therapies, whereas 47.3% of the warfarinised patients had their International Normalized Ratios above the recommended target range for their condition in the current guidelines. This suggests inadequate monitoring or compliance. DOACs-related bleeding seemed easily managed with a lesser need for reversing their anti-thrombotic effect and a shorter hospital stay when compared with patients receiving classical anticoagulants or antiplatelets. These findings might support the safety and potential cost-effectiveness of DOACs. Study 3 presents a 12-month retrospective cohort which investigated VTE risk associated with different cancer types and included 657 oncology patients. I assessed the performance of the original Khorana Score Risk Assessment Model (KS-RAM) and its six modifications, currently used in practice, in predicting VTE risk. I found limitations in these risk assessment tools in predicting VTE risk which might be attributed to limitations of including high-risk cancer types. Consequently, we developed and evaluated two VTE risk assessment models (VTE-RAM-1 and -2) using an innovative approach which demonstrated better VTE-risk prediction in cancer patients. The new VTE-RAM-1 will improve the current practice of VTE prevention in cancer patients, considering the observed improvement of VTE risk prediction and, consequently, better decision making on VTE prophylaxis. In the general conclusion, I discussed the contribution of this thesis to the TMR. I highlighted that the current practice used for VTE risk assessment, prevention, and treatment can be significantly improved to decrease VTE associated morbidity and mortality. Furthermore, I provided directions for future TMR in haemostatic disorders.
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Μιχαήλ, Γεώργιος Δ. "Ανάλυση χαρακτηριστικών περιεμμηνοπαυσιακού και μετεμμηνοπαυσιακού ενδομητρίου στην δισδιάστατη υπερηχοτομογραφία με χρήση τεχνικών ανάλυσης εικόνας." Thesis, 2007. http://nemertes.lis.upatras.gr/jspui/handle/10889/1195.

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Για τις Ευρωπαίες γυναίκες ο καρκίνος του σώματος της μήτρας αποτελεί το τέταρτο συχνότερο νεόπλασμα και την δέκατη σε σειρά αιτία θανάτου από καρκίνο. Ανεξάρτητα από το εάν η διακολπική υπερηχογραφία (TVS) αποτελεί δόκιμο μέσο διαλογής (screening) για την ανίχνευση ενδομητρικού καρκίνου σε ασυμπτωματικές μετεμμηνοπαυσιακές γυναίκες, εντούτοις κυριαρχεί στους διαγνωστικούς αλγόριθμους διερεύνησης κάθε μητρορραγίας προς αποκλεισμό του καρκίνου αυτού. Παράλληλα με τα πιθανά οφέλη από την ενσωμάτωση τεχνικών Υπερηχοϋστερογραφίας (SIS) και Doppler στην ενδομητρική απεικόνιση, η δισδιά- στατη “gray scale” διακολπική υπερηχογραφία οφείλει μεγάλο μέρος της προόδου της στην ώθηση από τις εξελίξεις της τεχνολογίας. Μετά την εισαγωγή των διακολπικών ηχοβολέων πολλαπλών συχνοτήτων (multifrequency) και της “αρμονικής” (harmonic) απεικόνισης, τα σύγχρονα υπερηχογραφικά μηχανήματα διαθέτουν επιλογές λογισμι- κού για ενίσχυση της ανάλυσης της αντίθεσης δομών, λεπτών ρυθμίσεων για εξέταση διαφορετικών τύπων ιστών, πολλαπλού εύρους εστίασης, μετάδοσης της δέσμης σε πλάγια διεύθυνση ως προς το ακουστικό παράθυρο, κ.α. Τα παραπάνω, καθώς και φίλτρα μείωσης του θορύβου βελτιστοποιούν την απεικόνιση του ενδομητρίου διευκολύνοντας την αποτίμησή του, ακόμη και στα χέρια άπειρων εξεταστών. Το πάχος της διπλής ενδομητρικής στιβάδας αποτελεί ιστορικά τον πλέον αδιαμφισβήτητο ποσοτικό δείκτη ενδομητρικού καρκίνου, ειδικά στην παρουσία μετεμμηνοπαυσιακής μητρορραγίας. Η συνδυασμένη μελέτη της ενδομητρικής μορφο- λογίας και πάχους παρέχει περισσότερες πληροφορίες, ειδικά στην αποτίμηση της “γκρίζας ζώνης” των 4-10 χιλιοστών ενδομητρικού πάχους, αν και τα ευρήματα των “μορφολογικών” αυτών μελετών δεν υπήρξαν πάντα σταθερά. Με δεδομένη τη σημασία της μορφολογίας στην αποτίμηση του ενδομητρικού ιστού, και αποσκοπώντας στην υπέρβαση του υποκειμενικού χαρακτήρα της ποιοτικής εκτίμησης της υπερηχογραφικής εικόνας, θα ήταν χρήσιμη η εφαρμογή αυτοματοποιημένων τεχνικών που αξιολογούν αντικειμενικά μορφολογικά χαρακτη- ριστικά, όπως η υποβοηθούμενη από υπολογιστή ανάλυση υφής, (“computerized texture analysis”). Στις ψηφιακές εικόνες, η υφή αντικατοπτρίζει τονικές (ένταση των εικονο- στοιχείων) και δομικές (χωρική κατανομή της έντασης των εικονοστοιχείων) ιδιότητες. Η “ανάλυση υφής” αναφέρεται σε αλγόριθμους που ποσοτικοποιούν περιεχόμενο και στοιχεία υφής που πιθανόν, ή όχι, να γίνονται αντιληπτά με το γυμνό μάτι. Δεδομένου ότι στην ιατρική απεικόνιση οι εικόνες περιλαμβάνουν πολλαπλές ιδιότητες των βιολογικών δομών, η ανάλυση υφής των εικόνων αυτών παρέχει ποσοτικές πληροφο- ρίες σχετικές με τα χαρακτηριστικά, τη μορφολογία και τις ιδιότητες των δομών αυτών. Σχήματα ταξινόμησης στηριζόμενα στην υφή έχουν χρησιμοποιηθεί με επιτυχία σε ποικιλία υπερηχογραφικών εφαρμογών. Η βασισμένη σε υπολογιστή αποτίμηση εικόνων του ενδομητρίου έχει βρει κυρίως εφαρμογή στη Υποβοηθούμενη Αναπαραγωγή, αλλά δεν έχει χρησιμοποιηθεί για τη διάγνωση ενδομητρικών κακοηθειών στην δισδιάστατη υπερηχογραφία. Σκοπός της διδακτορικής αυτής διατριβής είναι η αξιολόγηση του εφικτού της υποβοηθούμενης από υπολογιστή ανάλυσης υφής του ενδομητρικού ιστού όπως απεικονίζεται σε δισδιάστατες “gray scale” υπερηχογραφικές εικόνες. Περαιτέρω, διερευνήθηκε το αποτέλεσμα μιας τεχνικής επεξεργασίας βασισμένης σε μετασχη- ματισμό κυματίου (wavelet) στη διαδικασία τμηματοποίησης και χαρακτηρισμού του ενδομητρικού ιστού.
Cancer of the corpus uteri represents the fourth commonest neoplasm among European women and the tenth most common cause of death attributed to cancer. Irrespective whether the use of transvaginal ultrasonography (TVS) as a screening tool for detecting endometrial cancer in asymptomatic postmenopausal women is warranted, TVS dominates most diagnostic algorithms in assessing metrorrhagias to exclude this cancer. Alongside the potential benefits stemming from the integration of Saline Infusion Sonography) and Doppler modalities in endometrial imaging, gray scale TVS showed remarkable advances in the previous decades, largely attributed to the evolution in computer sciences. Following the introduction of multifrequency transvaginal probes and harmonic imaging, modern scanners are equipped with software options that enhance the resolution or the contrast between different structures, fine tune while assessing different types of tissue, implement different depth of focusing, transmit the ultrasonic beam in oblique directions to the acoustic window; all these features, in addition to de-speckle filters optimize the endometrial depiction, facilitating its assessment, even in the hands of moderately skilled operators. Double stripe endometrial thickness has illustrated a remarkable robustness over time as a quantitative indicator of endometrial cancer, especially in the presence of postmenopausal bleeding. The combined consideration of endometrial morphology and thickness has proven particularly beneficial, especially in the assessment of the 4-10 mm endometrial thickness “grey zone”, although the findings of the “morphologic” studies haven’t always been consistent. Given the importance of morphology in assessing endometrial tissue, and aiming to overcome the inherent subjectivity of the qualitative consideration of ultrasonic images, implementation of automated techniques assessing objective morphologic features such as “computerized texture analysis” would be beneficial. In digital images, texture reflects tonal (intensities of image pixels) and structural (spatial distribution of pixel intensities) properties. Texture analysis refers to algorithms that quantify texture content that may, or may not, be visually perceived. Since medical images capture various properties of biological structures, texture analysis of medical images can provide quantitative metrics relevant to structure, morphology and status of biological tissues. Texture based classification schemes have been successfully implemented in a variety of ultrasound applications. Computerized TVS assessment of endometrial morphology, has been applied mainly in assisted reproduction techniques; however, computerized texture analysis has not been implemented for diagnosing endometrial malignancies in grey scale TVS. The aim of this study is to investigate the feasibility of computerized texture analysis in characterizing endometrial tissue as depicted in 2D grey scale TVS images. Furthermore, we assess the effect of a wavelet-based image processing technique in the segmentation and subsequent characterization tasks of endometrial tissue.
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Βλαχοκώστα, Αλεξάνδρα. "Ανάπτυξη τεχνικών επεξεργασίας ιατρικών δεδομένων και συστημάτων υποστήριξης της διάγνωσης στη γυναικολογία." Thesis, 2014. http://hdl.handle.net/10889/8537.

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Η αυτόματη επεξεργασία εικόνων του ενδομητρίου αποτελεί ένα δύσκολο και πολυδιάστατο πρόβλημα, το οποίο έχει απασχολήσει πλήθος ερευνητών και για το οποίο έχει αναπτυχθεί μεγάλος αριθμός τεχνικών. Στην παρούσα διατριβή, παρουσιάζεται μια μεθοδολογική προσέγγιση, η οποία βασίζεται στη χρήση αλγορίθμων ψηφιακής επεξεργασίας και ανάλυσης εικόνων, για την αυτόματη εκτίμηση χαρακτηριστικών που περιγράφουν την αγγείωση και την υφή εικόνων του ενδομητρίου. Αφορμή της μελέτης αποτελεί ο ρόλος που διαπιστώνεται ότι διαδραματίζει η μεταβολή των τιμών των εν λόγω χαρακτηριστικών στην έγκαιρη διάγνωση των παθήσεων του ενδομητρίου. Στα πλαίσια της διατριβής, υλοποιήθηκε κατάλληλη μεθοδολογία για τον υπολογισμό ενός συνόλου χαρακτηριστικών τόσο για υστεροσκοπικές εικόνες, όσο και για ιστολογικές εικόνες του ενδομητρίου. Ιδιαίτερη βαρύτητα δόθηκε στην προ – επεξεργασία των εικόνων προκειμένου να προκύψει βελτίωση της ποιότητας καθώς και ενίσχυση της αντίθεσης αυτών. Στη συνέχεια, ανιχνεύτηκαν τα σημεία που αποτελούν τους κεντρικούς άξονες των υπό εξέταση αγγείων με χρήση διαφορικού λογισμού για τις υστεροσκοπικές εικόνες και υπολογίστηκε ένα σύνολο χαρακτηριστικών μεγεθών που περιγράφουν την αγγείωση και την υφή των εικόνων τόσο για τις υστεροσκοπικές όσο και για τις ιστολογικές εικόνες. Τέλος, εφαρμόστηκαν κατάλληλοι αλγόριθμοι με σκοπό την κατηγοριοποίηση των υστεροσκοπικών και των ιστολογικών εικόνων και συγκεκριμένα τον διαχωρισμό των παθολογικών και των φυσιολογικών εικόνων του ενδομητρίου. Παράλληλα, χρησιμοποιήθηκε η ROC ανάλυση στην απεικόνιση και ανάλυση της συμπεριφοράς των εν λόγω κατηγοριοποιητών.
Automatic analysis of the endometrial images is a difficult and multidimensional problem. For this reason, the number of papers and techniques regarding this issue is numerous. In this Thesis, a methodology is presented, based on advance image processing techniques in order to automatically estimate texture and vessel’s features in endometrial images. Motivation for the Thesis is the fact that the variation of the measurements of the specific features plays significant role in the seasonable diagnosis of endometrial disorders. Throughout this Thesis, an appropriate methodology is developed in order to estimate the features for the hysteroscopical and histological images of the endometrium. An important step is the pre – processing of the images in order to enhance the image quality and the image contrast. Then, the pixels that constitute the centerlines of vessels are detected by using differential calculus for the hysteroscopical images, only. Furthermore, the texture and vessel’s features in hysteroscopical and histological images are estimated. Finally, appropriate algorithms are applied in order to classify the hysteroscopical and histological images and distinguish pathological and normal endometrial images. ROC analysis is used in order to evaluate the discrimination power of the features that were estimated.
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Books on the topic "Bleeding canker"

1

Lark, Susan M. Dr. Susan Lark's heavy menstrual flow & anemia self help book: Effective solutions for premenopause, bleeding due to fibroid tumors, hormonal imbalance, endometriosis, endometrial cancer, and low blood count. Berkeley, Calif: Celestial Arts, 1995.

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L, Sutton Amy, ed. Blood and circulatory disorders sourcebook: Basic consumer health information about the blood and circulatory system and related disorders, such as anemia and other henoglobin diseases, cancer of the blood and associated bone marrow disorders, clotting and bleeding problems, and conditions that affect the veins, blood vessels, and arteries ... 2nd ed. Detroit, MI: Omnigraphics, 2005.

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King, Stephen. El umbral de la noche. Barcelona, Spain: Plaza y Janés, 2001.

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King, Stephen. Night Shift. New York: Knopf Doubleday Publishing Group, 2008.

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King, Stephen. Night shift. New York: Anchor Books, 2012.

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Danse macabre. Paris: J'ai lu, 2002.

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King, Stephen. Night Shift. New York, USA: Anchor Books, 2011.

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King, Stephen. Night Shift. London: New English Library, 1986.

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King, Stephen. Night shift. Oxford: ISIS Large Print, 1994.

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King, Stephen. Night shift. Thorndike, Me: G.K. Hall, 1994.

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Book chapters on the topic "Bleeding canker"

1

Green, S., B. E. Laue, R. Nowell, and H. Steele. "Horse Chestnut Bleeding Canker: A Twenty-First Century Tree Pathogen." In Challenges and Opportunities for the World's Forests in the 21st Century, 783–94. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-7076-8_35.

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Choi, Dong Wook, and Huisong Lee. "Postoperative Bleeding." In Pancreatic Cancer, 335–47. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-47181-4_32.

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Van Calsteren, Kristel, and Frédéric Amant. "Gynecological Cancer During Pregnancy." In Bleeding During Pregnancy, 77–96. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-9810-1_5.

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Rajaram, Shalini, and Garima Yadav. "Clinical Evaluation of Abnormal Uterine Bleeding." In Uterine Cancer, 45–51. New Delhi: Springer India, 2015. http://dx.doi.org/10.1007/978-81-322-1892-0_5.

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Mantha, Simon. "Bleeding Disorders Associated with Cancer." In Thrombosis and Hemostasis in Cancer, 191–203. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-20315-3_13.

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Pereira, Jaime. "Control of Bleeding in Cancer." In Cancer Treatment and Research, 305–26. Boston, MA: Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-79962-9_18.

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Zangari, Maurizio, F. Elice, G. Tricot, and L. Fink. "Bleeding Disorders Associated with Cancer Dysproteinemias." In Cancer Treatment and Research, 295–304. Boston, MA: Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-79962-9_17.

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Korte, Wolfgang. "Thrombosis and Bleeding in Cancer Patients." In The MASCC Textbook of Cancer Supportive Care and Survivorship, 303–18. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-90990-5_19.

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DeLoughery, Thomas. "Bleeding and Thrombosis in Cancer Patients." In Oncologic Emergency Medicine, 235–42. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26387-8_20.

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DeLoughery, Thomas G., and David C. Calverley. "Bleeding and Thrombosis in Cancer Patients." In Hemostasis and Thrombosis, 143–49. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-09312-3_28.

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Conference papers on the topic "Bleeding canker"

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Lima, Bruna Luisa Ferraço, Luís Carlos Sakamoto, Sthephanie Avesani João Figueiredo Carneiro, Natália Kathllen Colli Afonso, and Luiz Henrique Gebrim. "ASSESSMENT OF CHANGES IN BLEEDING PATTERNS AFTER CHEMOTHERAPY IN WOMEN WITH BREAST CANCER USING CONTRACEPTIVES." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1088.

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Introduction: The evolution regarding chemotherapy treatment through new medications and new regimens in women with a history of breast cancer over time allowed better therapeutic responses to the disease. One of the consequences of chemotherapy concerns the impairment of the follicular reserve and its hormonal production. Objectives: To assess the importance of the bleeding pattern in women with a history of breast cancer who underwent chemotherapy and the impact on the follicular population in determining ovarian failure. Methods: Between August and December 2020, 419 women were seen at the Family Planning outpatient clinic of the Women’s Health Reference Center (Hospital Pérola Byington), São Paulo, with 109 women having a history of breast cancer and undergoing a cross-sectional study, regarding the epidemiological characteristics of the care, the consequences to the bleeding pattern after chemotherapy treatment and the need for safe contraception. Results: The average age of women was 42.0 years, and the brown color was more prevalent in 49 women (45.0%). The mean age at diagnosis of breast cancer was 37.9 years, with 104 women (95.4%) presenting with invasive carcinoma and five cases (4.6%) with carcinoma in situ. Among the types of invasive carcinoma, luminal type B was present in 42 women (40.4%), HER2 in 25 (24.0%), triple negative in 19 (18.3%) and luminal A in 18 (17.3) %). 91 women (83.5%) underwent chemotherapy, and 82 other underwent hormonal treatment (75.2%), with 78 of them (95.1%) using tamoxifen. Obesity was present in 39 women (35.8%). Regarding the menstrual pattern, 38 women (34.9%) had amenorrhea after chemotherapy, but only six (15.8%) had confirmed laboratory menopause. Contraception through the copper intrauterine device (IUD) was performed in 82 of them (75.2%). Conclusions: Amenorrhea as a bleeding pattern after chemotherapy can be caused by impairment in the follicular population, causing ovarian failure and difficulty in pregnancy. On the other hand, contraception through a safe method such as copper IUDs until laboratory confirmation of menopausal status must be adopted. New studies should be carried out to better clarify this situation.
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Bhardwaj, Punita, T. K. Das, and S. Batra. "Laparoscopic radical hysterectomy: Results, recovery, recurrence – Our experience." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685396.

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Gynaecology Oncology is a beneficiary of Minimally Invasive Approach. We present our experience. The laparoscopic approach is associated with less surgical morbidity, per operative bleeding and shorter hospital stay though the duration of operation might be longer. It has a longer learning curve. Laparoscopic radical hysterectomy with pelvic lymphadenectomy is a safe surgical option for treatment of Gynaecological cancers taking into account amount of bleeding, complications recovery and recurrence.
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Meyer-Wilmes, P., M. Powerski, F. Fischbach, R. Damm, J. Omari, and M. Pech. "EP357 Transarterial embolisation for the treatment of acute gynecological cancer bleeding." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.416.

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Singh, S., V. Goel, V. Talwar, S. Raina, S. Mitra, U. Saxena, R. Shekhon, and S. Rawal. "Neo-adjuvant chemotherapy followed by surgery versus definitive chemo radiation as treatment for localized carcinoma cervix." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685273.

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Background: Cervical cancer is ranked as the most common cancer in Indian women, second most common cancer worldwide and the leading cause of death in the developing countries. In the developing countries majority of the patients are diagnosed at locally advanced stages. The standard treatment of locally advanced cervical cancer is concomitant chemoradiation (CTRT) using platinum based chemotherapy. However, some randomized studies have shown improved results for patients receiving neoadjuvant chemotherapy (NACT) followed by surgical resection in comparison to patient receiving radiation alone. The present study was designed to compare response to the treatment and survival of and NACT followed by radical surgery (RS) with CTRT in the patients of uterine cervix of a tertiary cancer care centre. Patients and Methods: Retrospective study was performed in locally advanced/advance stage patients of cervix UTERI registered in the institute between years 2009 to 2013. Patients were included in the two groups, group A consists of 89 patients who have received NACT + RS and 67 patients in group B who have received CTRT. Clinical records were reviewed with particular reference to presenting complaint, clinical stage, response to the therapy, disease free survival and overall survival. Statistical analysis was done using SPSS version 22. Results: In the neoadjuvant group (group A) (n=89) the median age of patients was 53 years (range 31-80 years), most of the patients (70%) were presented with complaint of postmenopausal bleeding. Of the total patients, 69 (77.5%) underwent to radical surgery and 5 (8.5%) received radiotherapy after NACT. From 69 patients, who had undergone to surgery, 54 (78.3%) had also received radiation. The overall response to induction chemotherapy was 84%. In the chemo radiation group (group B) (n=65) median age was 56 years (33-75 years). Vaginal bleeding (34%) followed by postmenopausal bleeding (32%) was major presenting complaint in this group. Overall response to the complete treatment was 91%. The median follow up time was 14.3 months in group A and 12.2 months in group B. The disease free survival for NACT group was 32 months (95% CI 26.8-36.5) whereas for CTRT group it was 28 months (95% CI 23.5-33) with 12 and 13 recurrences per group (p = .226). In NACT group overall survival was 46.2 months (95% CI 44-48.3) and for CTRT group it was 38.3 months (95%CI 36.6-40) with 3 and 2 deaths per group (p=.883). Conclusion: Present study shows comparable results, with no difference in survival between both the groups. However, NACT + RS group had showed better disease free and overall survival than another group. Further studies should be performed with larger number of patients and longer duration of follow up.
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Mangla, Akanksha, and Renuka Sinha. "Role of complementary cytology, colposcopy and histopathology in detecting premalignant and malignant lesions of cervix." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685253.

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Objective: Cervical cancer is the second most common gynecologic malignancy worldwide. India alone accounts for one fifth of total number of cases worldwide. The aim of our study was to calculate sensitivity, specificity, positive predictive value, negative predictive value, false positive rate and false negative rate of complementary cytology and colposcopy with histopathology as gold standard for detection of premalignant and malignant cervical lesions. Methods: A cross sectional study was conducted at Vardhman Mahavir Medical College and Safdarjung hospital, Delhi, India. 100 non pregnant females with complaint of post coital or irregular vaginal bleeding and those who had unhealthy cervix on visual inspection were included in study. Results: Colposcopy exhibited a high degree of accuracy in diagnosis of high grade lesions. Overall sensitivity of cytology was 50% whereas that of colposcopy was 83.3%. Cytology had specificity of 93.4% whereas colposcopy had specificity of 89.4%. 100% of high grade and invasive cancers on colposcopy were associated with similar findings on histology. The degree of agreement between cytology and colposcopy with histology was significant (p<0.001). Conclusion: Colposcopy is sensitive method as compared to cytology, especially in the higher grade lesions and combination of both methods appears to be of higher diagnostic importance.
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Gonçalves, Heloísa Helena Rengel, Mariana Burity Xavier, Alfredo Carlos Simões Dornellas de Barros, Graziela Couto de Carvalho, and Larissa Scarabucci Venezian. "ASSOCIATION BETWEEN LEVONORGESTRELRELEASING INTRAUTERINE SYSTEM AND BREAST CANCER." In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1005.

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Introduction: The association between the use of hormonal contraception and breast cancer has been debated in the medical community for years. Although older studies have suggested an increase in breast cancer risk with the use of combined oral contraceptive (COC) pills, more recent studies have demonstrated the relative safety of combined contraceptives composed of estrogen and progesterone. Isolated progestagens are usually prescribed to women who have menstrual cycle disturbances; however, literature on the association between the use of isolated progestagens and breast cancer is still controversial. The levonorgestrel intrauterine system (LNG-IUS) device is a long-duration, reversible contraceptive. It has become popular due to its high efficacy as a birth control method and other beneficial effects, such as control of abnormal uterine bleeding and endometrial protection. Nevertheless, its safety regarding breast cancer has is still questioned. Furthermore, it has been debated whether it would be a viable choice for birth control for breast cancer survivors, as well as a tool for endometrial protection among women who use tamoxifen, which leads to endometrial thickening, polyps, and even hyperplasia and endometrial cancer. Objective: This study aims to present a literary review of the main articles within the theme of the use of LNG-IUS and its safety for breast cancer survivors and in the general population. Methods: A literature review was conducted for articles with this theme, using an electronic library, with predetermined keywords. Results: In total, 25 articles were selected that fulfilled the inclusion criteria. Progesterone has a proliferative effect on the breast during the luteal phase of the menstrual cycle, in addition to inducing alveologenesis during puberty and ductal branching during pregnancy. This proliferative effect takes place through the expression of cyclin D1 on nPR-expressing cells. Moreover, it presents a paracrine effect on the adjacent cells that do not express hormone receptors, through the activation of membrane receptors that activate the nuclear factor kappa beta — the receptor activator of NF-κβ (RANK). Studies with animals showed that carcinogenesis was accelerated after the administration of progestagens, mediated by RANK ligands (RANKL). It is also known that levonorgestrel has an action on the 17-betahydroxysteroid dehydrogenase (17β-HSDs) enzymes on T47D epithelial breast carcinoma cells, increasing the bioactivity of estrogen on these cells. Comparing the use of LNG-IUS with the use of levonorgestrel orally, users of LNG-IUS have significantly lower levonorgestrel serum levels. Some populational studies have evaluated the association of LNG-IUS use and the risk of breast cancer, with discordant results. In some studies, for women who have used LNG-IUS, the risk was up to 73% higher. Regarding its safety for breast cancer survivors using tamoxifen, it has been shown that there is little or no difference in breast cancer recurrence with the use of LNG-IUS. However, other authors claim that there are not enough data to confirm the safety concerning breast cancer recurrence, and its use may lead to irregular bleeding and invasive procedures to assess the endometrial layer. Conclusion: In populational studies, the use of LNG-IUS increases breast cancer risk. In breast cancer survivors who use tamoxifen, LNG-IUS seems to protect the endometrium, but more studies are necessary to confirm its safety for breast cancer recurrence.
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Caprini, J. A., A. Mitchell, L. Rao, and J. P. Vagher. "EVALUATION OF PREOPERATIVE HEMOSTATIC SCREENING." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643075.

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The records of 705 surgical patients were reviewed to ccrrpare the value of history, bleeding risk factors, preoperative template bleeding time (BT) and activated partial thromboplastin time (APTT) in predicting excessive operative bleeding and/or the need for intra or postoperative transfusion. Bleeding was classified as normal or excessive by a panel of physicians evaluating operative blood loss, operative pathology including trauna, postoperative hematocrit, tube drainage, wound hematoma, etc. These assessments were compared with the incidence of intra/postoperative blood transfusions. 25% of the patients had excessive intra/postoperative bleeding and 35% of the population were transfused. A BT > 10 minutes and an APTT > 111% of pooled-normal-piasma were considered abnormal. 9.6% of patients had an abnormal BT and showed a statistically significant higher incidence of bleeding (42.6%) and transfusion (58.8%) compared with a 23.2% incidence of bleeding and 32.3% incidence of transfusion in those with a normal BT (p< 0.001). 18.7% of patients had an abnormal APTT and 31.8% bled compared to 23.6% of those with a normal APTT (p< 0.05). When both tests were abnormal, 54.5% bled compared to 22.4% when the tests were normal (p< 0.001). When both tests were abnormal 63.6% were transfused whereas only 32.1% with normal tests were transfused (p< 0.005). 72.5% of the 705 patients were considered high risk because of a history of bleeding, drug ingestion, cancer, sepsis, trauma, clinical bleeding, diabetes, uremia, or cardiovascular surgery. 76.3% of the patients who bled at surgery came from this high risk group. Of the high risk patients, those with an abnormal BT bled more often (42.9%) (p< 0.005) and were transfused more (60.3%) (p< 0.001) than those high risk patients with a normal BT (24.2% bled and 36.4% were transfused). Although a greater percentage of high risk patients with an abnormal APTT bled and were transfused, the comparisons were not statistically significant. Patients with abnormal tests, regardless of history, whose surgery was delayed because of the test results bled less often (13.8%) than those whose surgery was not delayed despite abnormal tests (34.8%) (p< 0.05). 14.4% of patients without any history or risk factors (Low Risk) had abnormal tests and bled more often than those low risk patients with normal tests but the comparison was not statistically significant. These results suggest that a combination of history, high risk factors, BT and APTT can better identify surgical patients more likely to bleed excessively or require transfusions than any one parameter. No combination of parameters will identify all bleeders, but including these two tests increases predictive accuracy in certain groups. We feel the cost of these two tests ($40) is much less than the potential expense of unexpected bleeding, particularly if transfusions are required or transfusion related complications occur.
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Honeyman, L., J. Davies, S. Kolhe, J. Dasgupta, D. Casayuran, and A. Phillips. "780 Frequency and duration of post-menopausal bleeding – risk stratification for endometrial cancer." In ESGO 2021 Congress. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/ijgc-2021-esgo.193.

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"Freezing and Thawing Resistance of Concrete With Excessive Bleeding and Its Improvement." In SP-170: Fourth CANMET/ACI International Conference on Durability of Concrete. American Concrete Institute, 1997. http://dx.doi.org/10.14359/6858.

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Marconi, Letizia, Federica Restivo, Laura Carrozzi, Ferruccio Aquilini, and Antonio Palla. "Different mortality, recurrence and bleeding between cancer and non cancer patients with pulmonary embolism (PE): 1 year follow-up." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa564.

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Reports on the topic "Bleeding canker"

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hou, xianbing, dandan chen, tongfei cheng, dan wang, xiaojun dai, yao wang, bixian cui, et al. Bleeding risk of anticoagulant therapy in patients with advanced cancer in palliative care settings：a protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0064.

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Review question / Objective: The systematic review aim to provide synthesised and appraised evidence to assess the bleeding risk of anticoagulant therapy in patients with advanced cancer in palliative care settings. Condition being studied: Cancer is a recognized risk factor for venous thromboembolism (VTE). The main forms of thromboembolic disease include pulmonary embolism (PE) and deep vein thrombosis (DVT). Given their diagnosis and often poor physical status, patients with advanced cancer are at particularly high risk of developing VTE, resulting in reduced activity levels or even immobility. The exact incidence and prevalence of VTE in the population of cancer patients receiving hospice or palliative care has not been well investigated and few reports are available. Clinical studies have not yet determined whether such patients benefit from anticoagulant therapy and whether there is an increased risk of bleeding and death.
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