Academic literature on the topic 'Blinatumomab'

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Journal articles on the topic "Blinatumomab"

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&NA;. "Blinatumomab." Reactions Weekly &NA;, no. 1339 (2011): 12. http://dx.doi.org/10.2165/00128415-201113390-00033.

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Buie, Larry W., Joshua J. Pecoraro, Troy Z. Horvat, and Ryan J. Daley. "Blinatumomab." Annals of Pharmacotherapy 49, no. 9 (2015): 1057–67. http://dx.doi.org/10.1177/1060028015588555.

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Chen, Yun-Hsiang, Yun Wang, Cheng-Hao Liao та Shu-Ching Hsu. "The potential of adoptive transfer of γ9δ2 T cells to enhance blinatumomab’s antitumor activity against B-cell malignancy". Scientific Reports 11, № 1 (2021). http://dx.doi.org/10.1038/s41598-021-91784-1.

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AbstractBlinatumomab, a bispecific T cell engager (BiTE) antibody targeting CD19 and CD3ε, can redirect T cells toward CD19-positive tumor cells and has been approved to treat relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL). However, chemotherapeutic regimens can severely reduce T cells’ number and cytotoxic function, leading to an inadequate response to blinatumomab treatment in patients. In addition, it was reported that a substantial portion of R/R B-ALL patients failing blinatumomab treatment had the extramedullary disease, indicating the poor ability of blinatumomab in
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"Blinatumomab." Reactions Weekly 1854, no. 1 (2021): 87. http://dx.doi.org/10.1007/s40278-021-95418-1.

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"Blinatumomab." Reactions Weekly 1840, no. 1 (2021): 91. http://dx.doi.org/10.1007/s40278-021-90234-5.

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"Blinatumomab." Reactions Weekly 1837, no. 1 (2021): 115. http://dx.doi.org/10.1007/s40278-021-88714-3.

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"Blinatumomab." Reactions Weekly 1843, no. 1 (2021): 82. http://dx.doi.org/10.1007/s40278-021-91184-z.

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"Blinatumomab." Reactions Weekly 1847, no. 1 (2021): 101. http://dx.doi.org/10.1007/s40278-021-92658-2.

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"Blinatumomab." Reactions Weekly 1846, no. 1 (2021): 64. http://dx.doi.org/10.1007/s40278-021-92312-z.

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"Blinatumomab." Reactions Weekly 1925, no. 1 (2022): 131. http://dx.doi.org/10.1007/s40278-022-23908-8.

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Dissertations / Theses on the topic "Blinatumomab"

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Volpato, Francesca <1986&gt. "L'utilizzo clinico del blinatumomab nella terapia della leucemia linfoblastica acuta: l'esperienza di Bologna." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amsdottorato.unibo.it/8651/1/tesi%20FINALE%20RISULTATI.pdf.

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La leucemia acuta linfoblastica a cellule B è una patologia rara nell'adulto (insorgenza pari a 1.1/100.000 abitanti) caratterizzata da una pessima prognosi. Risulta definita da tassi di sopravvivenza globale a 5 anni che nonostante gli sviluppi terapeutici negli ultimi due decenni non sono incrementati, con valori di sopravvivenza media del 49% nei pazienti standard-risk e del 24% nei pazienti high-risk. L'utilizzo di anticorpi ingegnerizzati bispecifici BiTE sembra dare risultati promettenti nei pazienti con neoplasie ematologiche. Nel nostro centro sono stati avviati tre protocolli di trat
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Dufner, Vera Christine Verfasser], Ralf C. [Gutachter] [Bargou, Götz [Gutachter] Gelbrich, Peter [Gutachter] Heuschmann, and Maria-Elisabeth [Gutachter] Göbeler. "Effektivität und Sicherheit von Blinatumomab im Long-term Follow-up bei Non-Hodgkin-Lymphom-Patienten / Vera Christine Dufner ; Gutachter: Ralf Bargou, Götz Gelbrich, Peter Heuschmann, Maria-Elisabeth Göbeler." Würzburg : Universität Würzburg, 2020. http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-184762.

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Dufner, Vera Christine [Verfasser], Ralf [Gutachter] Bargou, Götz [Gutachter] Gelbrich, Peter [Gutachter] Heuschmann, and Maria-Elisabeth [Gutachter] Göbeler. "Effektivität und Sicherheit von Blinatumomab im Long-term Follow-up bei Non-Hodgkin-Lymphom-Patienten / Vera Christine Dufner ; Gutachter: Ralf Bargou, Götz Gelbrich, Peter Heuschmann, Maria-Elisabeth Göbeler." Würzburg : Universität Würzburg, 2020. http://d-nb.info/1210426390/34.

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Dufner, Vera Christine. "Effektivität und Sicherheit von Blinatumomab im Long-term Follow-up bei Non-Hodgkin-Lymphom-Patienten." Doctoral thesis, 2020. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-184762.

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Das Non-Hodgkin-Lymphom (NHL) steht an siebter Stelle der Inzidenzen aller Krebserkrankungen, mit jährlich steigender Tendenz. Wie kann einer so gefährlichen und heterogenen Krankheitsentität in der heutigen Medizin angemessen begegnet werden? Neben etablierten Therapien, die geraden bei rezidivierten oder refraktären NHL an ihre Grenzen stoßen, bieten experimentelle Therapieansätze neue Hoffnung: Blinatumomab ist ein bispezifischer Antikörper, der durch seine beiden Domänen als Adapter für die T-Zelle und die Tumor-Zelle fungiert und eine Zytolyse der malignen B-Zelle induziert. Bei der ALL f
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Books on the topic "Blinatumomab"

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Hodgkiss, Andrew. Psychiatric consequences of cancer treatments: therapeutic monoclonal antibodies. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198759911.003.0009.

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The adverse psychiatric consequences of a range of monoclonal antibodies used to treat cancer are reviewed. Bevacizumab disrupts endothelial function at the blood–brain barrier and can provoke posterior reversible encephalopathy syndrome. The immune checkpoint inhibitors cause autoimmune hypophysitis and thyroiditis with associated psychopathology. Rituximab causes profound immunosuppression of B lymphocytes, and hence can reactivate childhood JC virus infection to cause progressive multifocal leucoencephalopathy. The marked neuropsychiatric toxicity of blinatumomab is described.
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Book chapters on the topic "Blinatumomab"

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Stelljes, Matthias, David I. Marks, and Sebastian Giebel. "Acute Lymphoblastic Leukemia in Adults." In The EBMT Handbook. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-44080-9_72.

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AbstractThe prognosis of patients with acute lymphoblastic leukemia is constantly improving. Beside optimization strategies of conventional chemotherapies and close monitoring of treatment response (e.g. by PCR-based measurement of measurable disease, which helps to early identify patients at risk for relapse), the integration of antibody (e.g. anti-CD20)/antibody-based drugs (blinatumomab and inotuzumab-ozogamicin) to frontline and/or salvage therapy protocols led to significant improvements. However, allogeneic HCT still plays a fundamental role in the treatment of high-risk patients in 1st
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Takada, Satoru. "Blinatumomab for Acute Lymphoblastic Leukemia: Clinical Pharmacology and Therapeutic Results." In Chemotherapy for Leukemia. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3332-2_8.

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Baeuerle, Patrick A. "Development of T-Cell-Engaging Bispecific Antibody Blinatumomab (Blincyto®) for Treatment of B-Cell Malignancies." In Successful Drug Discovery. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527808694.ch5.

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Simpson, Michelle C., and Eric G. Schaefer. "Blinatumomab." In Extended Stability for Parenteral Drugs. ASHP, 2022. http://dx.doi.org/10.37573/9781585286720.022.

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"Blinatumomab." In Extended Stability for Parenteral Drugs. American Society of Health-System Pharmacists, 2017. http://dx.doi.org/10.37573/9781585285280.019.

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"Blinatumomab." In ASHP® Injectable Drug Information™. ASHP, 2021. http://dx.doi.org/10.37573/9781585286850.054.

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Phelps, Stephanie J., Tracy M. Hagemann, and Kelley R. Lee. "Blinatumomab." In Pediatric Injectable Drugs. ASHP, 2024. http://dx.doi.org/10.37573/9781585287192.041.

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"Blinatumomab." In ASHP® Injectable Drug Information™. ASHP, 2024. https://doi.org/10.37573/9781585287444.055.

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Conference papers on the topic "Blinatumomab"

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van den Heuvel, Robert. "Blinatumomab candidate for standard-of-care in newly diagnosed B-ALL." In 64th ASH Annual Meeting, edited by Gert Ossenkoppele. Medicom Medical Publishers, 2023. http://dx.doi.org/10.55788/50f6de65.

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van den Heuvel, Robert. "Blinatumomab may improve outcomes in patients with B-cell ALL undergoing ASCT." In EBMT Annual Meeting 2023, edited by Prof Gert Ossenkoppele. Medicom Medical Publishers, 2023. http://dx.doi.org/10.55788/692c5ed7.

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Hizal, Mina, Deniz Yaşar, Tuğba Ramaslı Gürsoy, Şule Yeşil, and Ali Fettah. "Blinatumomab-Induced Pneumonitis in a Pediatric Case in B-cell Acute Lymphoblastic Leukemia." In ERS Congress 2024 abstracts. European Respiratory Society, 2024. http://dx.doi.org/10.1183/13993003.congress-2024.pa551.

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van den Heuvel, Robert. "Blinatumomab reduces toxicity in the consolidation phase in paediatric high-risk B-cell ALL." In 65th ASH Annual Meeting, edited by Gert Ossenkoppele. Medicom Medical Publishers, 2024. http://dx.doi.org/10.55788/19866a5c.

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Dubke, J., B. Schattling, I. A. Bley, M. Klokow, I. Müller та M. Queudeville. "γ/δ-T cells for the immunotherapy of pediatric acute lymphoblastic leukemia with blinatumomab". У 35. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1786568.

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Lazaro, J., C. Alcon, A. Lissat, J. Montero, and C. Eckert. "Exploring Synergistic Approaches to Enhance Blinatumomab&apos;s Efficacy in Acute Lymphoblastic Leukemia." In 35. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1786596.

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Hassani, L., N. Osman, S. Nguyen, et al. "PP-036 Blinatumomab: organisational and economic optimisation of treatment and proposal for scheduled patient care." In 22nd EAHP Congress 22–24 March 2017 Cannes, France. British Medical Journal Publishing Group, 2017. http://dx.doi.org/10.1136/ejhpharm-2017-000640.483.

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Qiang, Xiangnan, Ronghua Zhang, Zhixiang Zhang, et al. "294 Comparison of preclinical efficacy between CD19 CAR-T and CD3×CD19 bispecific antibody (blinatumomab)." In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.0294.

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Repaire, T. du, P. Vigne, A. Savry, L. Gauthier-Villano, B. Pourroy, and P. Bertault-Peres. "CP-172 Visual compatibility of BLINATUMOMAB with selected co-administrated drugs during simulated y site administration." In 22nd EAHP Congress 22–24 March 2017 Cannes, France. British Medical Journal Publishing Group, 2017. http://dx.doi.org/10.1136/ejhpharm-2017-000640.170.

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Radichev, Ilian, Jiwon Yang, Won Lee, Destanie Rose, and James G. Keck. "1259 Comparison of blinatumomab and biosimilar CD19xCD3 BiTE responses in PBMC-humanized mice used as a preclinical lymphoma mouse model." In SITC 38th Annual Meeting (SITC 2023) Abstracts. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.1259.

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