Relevant bibliographies by topics / Blindness – age factors

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Blindness – age factors'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Blindness – age factors"

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Mogk, Marja. "The Difference that Age Makes: Cultural Factors that Shape Older Adults’ Responses to Age-Related Macular Degeneration." Journal of Visual Impairment & Blindness 102, no. 10 (2008): 581–90. http://dx.doi.org/10.1177/0145482x0810201002.

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This article suggests that approaching vision loss from age-related macular degeneration from a sociocultural perspective, specifically considering perceptions of aging, blindness, disability, and generational viewpoints and norms, may be critical to understanding older adults’ responses to vision loss and visual rehabilitation.
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Chaudhary, Santosh, Poonam Lavaju, Bhuwan Govinda Shrestha, Sangeeta Shah, and Sanjib Kumar Chaudhary. "Factors affecting the visual outcome of pediatric cataract surgery: a hospital based prospective study in eastern Nepal." Nepalese Journal of Ophthalmology 9, no. 2 (2018): 143–48. http://dx.doi.org/10.3126/nepjoph.v9i2.19258.

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The World Health Organization’s (WHO) global initiative for the elimination of avoidable blindness by the year 2020 (Thylefors et al., 1995) has prioritized the control of childhood blindness. Currently cataract remains one of the most important causes of treatable blindness in children (Giles et al., 2016).In Nepal, as in other developing countries, cataract is believed to be a leading cause of blindness in children. According to The Nepal Blindness Survey from 1978 to 1980, congenital cataract accounted for 16.3% of blindness detected in children under the age of 15 years (Brilliant et al.,
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Nuertey, Benjamin D., Kwesi Nyan Amissah-Arthur, Joyce Addai, et al. "Prevalence, Causes, and Factors Associated with Visual Impairment and Blindness among Registered Pensioners in Ghana." Journal of Ophthalmology 2019 (October 7, 2019): 1–10. http://dx.doi.org/10.1155/2019/1717464.

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Purpose. To determine the prevalence, causes, and factors associated with presenting visual impairment and blindness among pensioners. Design. A nationwide cross-sectional study. This study was part of the analysis on data obtained in the pensioners’ medical survey conducted among members of the National Pensioners Association in Ghana. Method. (i) Setting: it was a multicenter study involving thirteen centers throughout Ghana with a center in each regional capital. (ii) Study population: the study involved 4813 pensioners. (iii) Observation procedures: data were captured through the use of qu
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Connell, Paul P., Pearse A. Keane, Evelyn C. O'Neill, et al. "Risk Factors for Age-Related Maculopathy." Journal of Ophthalmology 2009 (2009): 1–39. http://dx.doi.org/10.1155/2009/360764.

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Age-related maculopathy (ARM) is the leading cause of blindness in the elderly. Although beneficial therapeutic strategies have recently begun to emerge, much remains unclear regarding the etiopathogenesis of this disorder. Epidemiologic studies have enhanced our understanding of ARM, but the data, often conflicting, has led to difficulties with drawing firm conclusions with respect to risk for this condition. As a consequence, we saw a need to assimilate the published findings with respect to risk factors for ARM, through a review of the literature appraising results from published cross-sect
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El Gilany, A. H., S. El Fedawy, and M. Tharwat. "Causes of blindness and needs of the blind in Mansoura, Egypt." Eastern Mediterranean Health Journal 08, no. 01 (2002): 6–17. http://dx.doi.org/10.26719/2002.8.1.6.

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A study of 113 blind people in Mansoura, Egypt highlighted the causes and risk factors for blindness, and health and social care needs of the blind. In two-thirds of cases, blindness occurred before 10 years of age. Risk factors for blindness were reported by more than half the study population. Congenital causes accounted for almost half the cases. The commonest causes of bilateral blindness were corneal opacities, cataract and glaucoma. Almost three-quarters of causes were avoidable. Health and social care for this group was inadequate and more than half would benefit from further management
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Khanal, Shankar Prasad, Krishna Prasad Acharya, Pravat Uprety, and Santosh Kumar Shah. "Statistical Modeling on Blindness and Visual Impairment Data." Journal of Institute of Science and Technology 19, no. 1 (2015): 1–6. http://dx.doi.org/10.3126/jist.v19i1.13818.

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Blindness and visual impairment remain leading causes of disability in the world, and also considered one of the major eye problems in Nepal. This study was planned to identify the significant risk factors of visual impairment and blindness based on hospital data. The analysis is based on 2000 patients’ information with age ?40 years retrospectively. Logistic regression model is used to identify the risk factors of visual impairment. Altogether 710(36%) subjects were having visually impaired (low vision) and very few 29(1.45%) were having blindness. The proportion of having visual impairment a
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Cabrera, Cathleen Camille, Joseph Anthony Tumbocon, and John Mark de Leon. "Progression to blindness in 20 years among patients with glaucomatous visual field loss in a tertiary hospital in the Philippines." BMJ Open Ophthalmology 5, no. 1 (2020): e000424. http://dx.doi.org/10.1136/bmjophth-2019-000424.

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ObjectiveTo determine visual field (VF) rates of change among patients with glaucomatous VF loss and proportion of those becoming blind based on residual life expectancy and factors associated with fast progression.Methods and analysisThis was a retrospective study of the VFs of patients with glaucomatous VF defects in at least one eye. Baseline and final VFs were reviewed. Rates of VF change (decibels (dB)/year) for each eye, together with the residual life expectancy based on age and sex, were used to predict mean deviation/defect (MD) at the end of expected lifetime. Blindness was defined i
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Sun, Yi, Guangming Jin, Mengting Yang, Jing Fu, Xueyi Chen, and Bingsheng Lou. "Prevalence, Risk Factors, and Causes of Visual Impairment in an Elderly Chinese Uygur Population in Southern Xinjiang." Journal of Ophthalmology 2021 (April 5, 2021): 1–8. http://dx.doi.org/10.1155/2021/8843032.

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Purpose. To investigate the prevalence, risk factors, and major causes of visual impairment (VI) in an elderly Chinese Uygur population in southern Xinjiang. Methods. This was a population-based cross-sectional study. Participants aged 50 years and older from Haohan Country, Xinjiang Uygur Autonomous Region, were enrolled from August 2018 to December 2018 using cluster sampling. Participants underwent examinations including presenting visual acuity (PVA), pinhole vision, slit-lamp, intraocular pressure, and direct ophthalmoscopy. Participants’ education and demographic information was collecte
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Bantihun, Ajebew, Kedir Abdela Gonete, Azeb Atnafu Getie, and Asmamaw Atnafu. "Child Night Blindness and Bitot’s Spots Are Public Health Problems in Lay Armachiho District, Central Gondar Zone, Northwest Ethiopia, 2019: A Community-Based Cross-Sectional Study." International Journal of Pediatrics 2020 (November 17, 2020): 1–11. http://dx.doi.org/10.1155/2020/5095620.

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Background. Night blindness (XN) is a condition in which a person cannot see in dim light and is the earliest clinical manifestation of vitamin A deficiency. Globally, vitamin A deficiency is a public health problem in 122 countries, of which 45 countries have moderate to severe child night blindness. Therefore, this study is aimed at assessing the prevalence and associated factors of night blindness and Bitot’s spot among children aged 24-59 months. Methods. A community-based cross-sectional study was employed from February to March 2019 among children aged 24-59 months in the Lay Armachiho D
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Zhao, Mingyue, Ali Hassan Gillani, Fakir Mohammad Amirul Islam, et al. "Factors Associated with Knowledge, Attitude and Practices of Common Eye Diseases in General Population: A Multicenter Cross-Sectional Study from Pakistan." International Journal of Environmental Research and Public Health 16, no. 9 (2019): 1568. http://dx.doi.org/10.3390/ijerph16091568.

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High prevalence of blindness coupled with low public awareness of eye diseases is a severe problem in Pakistan. The objective of this study was to evaluate the awareness, attitude and practices related to common ocular problems and eye care use among general population of Punjab, Pakistan. Data were collected cross-sectionally, using random selection of participants from five districts of Punjab, Pakistan. A pre-tested questionnaire was used to collect the data from January to March 2017. The ordinal data were converted to interval--based data by Rasch analysis, which is termed as “knowledge s
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Dissertations / Theses on the topic "Blindness – age factors"

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Sulaiman, Rania S. "Mechanistic and therapeutic evaluation of a novel antiantiogenic small molecule." Diss., 2016. http://hdl.handle.net/1805/10604.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Choroidal neovascularization (CNV) is the vision-threatening characteristic of wet age-related macular degeneration (AMD), a major cause of blindness affecting almost 2 million elderly Americans. The current approved treatments target the dominant angiogenic mediator, vascular endothelial growth factor (VEGF). However, repeated injections of anti-VEGF drugs can cause ocular and systemic side effects, and about 30% of wet AMD patients are non-responsive. There is thus an unmet need to develop VEGF-independent antiangiogenic mole
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Books on the topic "Blindness – age factors"

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Vision problems in the U.S.: Prevalence of adult vision impairment and age-related eye disease in America. Prevent Blindness America, 2002.

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Martin, Jeffrey J. Body Image. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190638054.003.0037.

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It has often been wrongly assumed that people with disabilities have poor body image. The purpose of this chapter is to review the body image research involving individuals with impairments and investigating if they are dissatisfied with their appearance. People with disabilities such as cerebral palsy, blindness, and amputations are all very different, and their impairments are likely to differ in many other respects that can play a role in body image self-perceptions. The lack of unanimity across the research reviewed here suggests that disability type, disability severity, visibility, durat
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Traul, David E. Postoperative Visual Loss in Spine Surgery. Edited by David E. Traul and Irene P. Osborn. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190850036.003.0026.

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Postoperative visual loss (POVL) is a rare but devastating condition associated with many types of nonocular surgery. In spine surgery, the most common causes of POVL are ischemic optic neuropathy (ION), central retinal artery occlusion (CRAO), and cortical blindness. Although the association of POVL with spine surgery has long been recognized, the low incidence of this complication hinders the identification of patient and perioperative risk factors and limits our understanding of the causes of POVL. In adult spine surgery, POVL is most frequently attributed to ION whereas CRAO is more common
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Nass, MD, Ruth, and Yitzchak Frank, MD, eds. Cognitive and Behavioral Abnormalities of Pediatric Diseases. Oxford University Press, 2010. http://dx.doi.org/10.1093/oso/9780195342680.001.0001.

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This book provides a detailed account of intellectual, other neuropsychological and behavioral manifestations of general pediatric diseases. The conditions discussed include the whole range of pediatric diseases - genetic syndromes, other congenital conditions, metabolic, endocrine, gastrointestinal, infectious, immunologic, toxic, trauma, and neoplastic, as well as sensory disabilities including deafness and blindness. Although the book is not intended to discuss cognitive and behavioral manifestations of conditions usually considered to be primary neurological disease, some of those, includi
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Book chapters on the topic "Blindness – age factors"

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Hernan Gonzalez-Cortes, Jesus, Jesus Emiliano Gonzalez-Cantu, Aditya Sudhalkar, et al. "Treatment Algorithm in Proliferative Diabetic Retinopathy. From Protocols to the Real World." In Diabetic Eye Disease - From Therapeutic Pipeline to the Real World [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99843.

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Diabetes mellitus is a global epidemic that leads to multiple macrovascular and microvascular complications. The complex interrelated pathophysiological mechanisms triggered by hyperglycemia underlie the development of diabetic retinopathy (DR). Proliferative diabetic retinopathy (PDR) is a microvascular complication, considered the main cause of irreversible blindness in patients of productive age in the world. On the other hand, diabetic macular edema (DME) remains the clinical feature most closely associated with vision loss. In general, both manifestations are due to an increase in inflammatory factors, such as specific pro-inflammatory prostaglandins, interleukins and angiogenic substances including vascular endothelial growth factor (VEGF). Laser photocoagulation and VEGF inhibitors have been shown to be effective in the treatment of PDR and DME. Currently, randomized protocols suggest that VEGF inhibitors therapy could displace laser photocoagulation in the treatment of PDR with and without the presence of DME. The ongoing discussion still prevails about the different treatment modalities for both retinal manifestations in real-world settings.
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Salim, Sarwat. "Evidence-Based Guidelines in Management of Glaucoma." In Glaucoma. Oxford University Press, 2012. http://dx.doi.org/10.1093/oso/9780199757084.003.0014.

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Early detection and treatment of primary open-angle glaucoma (POAG) are important to reduce the burden of blindness and its economic impact on society. This chapter will address the evidence-based guidelines for treating POAG. POAG is defined as an optic neuropathy with associated visual field loss for which elevated IOP is a major risk factor. To date, most of our treatment strategies are directed at reducing IOP, either with medical therapy, laser surgery, or incisional surgery, with medical therapy being the most common initial course of treatment. Three important questions often confront a glaucoma specialist when initiating therapy: Who needs to be treated?, how should a patient be treated, and to what extent? The Ocular Hypertension Study (OHTS) has provided insightful information to guide us in treatment of ocular hypertensives who may present with some risk factors and clinical findings but not others. OHTS demonstrated that reducing IOP by 20% with medical therapy in patients with ocular hypertension reduced the risk of developing glaucoma to 4.4% in the treated group versus 9.5% in the observation group at 5–year follow-up. •This clinical trial not only established the efficacy of lowering IOP with medical therapy but also identified the risk factors for developing glaucoma in these patients. •Older age, higher IOP, larger cup-disc diameter, higher pattern standard deviation, and thin central corneal thickness were determined to be significant risk factors by multivariate analysis. •Although family history and race were not found to be independent risk factors in OHTS, their association with glaucoma has been well established with other large population-based studies, such as the Baltimore Eye Survey. • Of note, a majority of untreated patients (nearly 90%) in the first phase of OHTS did not show any evidence of progression, a finding that emphasized the need to individualize therapy based on assessing risk factors and clinical findings in a given patient.
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Remschmidt, Helmut, and Gerd Schulte-Körne. "Specific developmental disorders in childhood and adolescence." In New Oxford Textbook of Psychiatry. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199696758.003.0213.

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The term ‘specific developmental disorders’ includes a variety of severe and persistent difficulties in spoken language, spelling, reading, arithmetic, and motor function. Skills are substantially below the expected level in terms of chronological age, measured intelligence, and age-appropriate education and cannot be explained by any obvious neurological disorder or any specific adverse psychosocial or family circumstances. As the deficits are quite substantial, analogies were initially made to neurological concepts and disorders such as word-blindness, alexia, aphasia, and apraxia, thus giving rise to the notion that neurological deficits are the aetiological basis of these disorders. Since this could not be demonstrated, the next step was to define the disorders in a more functional way, taking into account not only psychometric testing but also psychosocial risk factors and the quality of schooling and education. Today, numerous findings support the validity of the diagnostic concept of specific developmental disorders. These disorders and pervasive developmental disorders have the following features in common (ICD-10): ♦ An onset that invariably appears during infancy or childhood. ♦ An impairment or delay in the development of functions that are strongly related to biological maturation of the central nervous system. ♦ A steady course that does not involve the remissions and relapses that tend to be characteristic of many mental disorders. Thus the term ‘specific developmental disorders’ reflects the fact that the deficits are circumscribed and relatively isolated against the background of an otherwise undisturbed psychological functioning.
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Selikowitz, Mark. "Social clumsiness." In ADHD: The Facts. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198867371.003.0008.

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To acquire age-appropriate social skills, certain parts of the brain need to develop normally. Children with ADHD may experience social difficulties and experience what is called a social cognition deficit. This chapter outlines social clumsiness in ADHD. It discusses social cognition as a function of the brain, specific social competence deficits (social blindness, egocentricity, lack of appropriate inhibition, insatiability, insensitivity to style and convention, lack of responsiveness, over-talkativeness, difficulties reading facial expression, aggressive tendencies, lack of judgment, poor understanding of group dynamics, misinterpretation of feedback, poor social prediction, poor social memory, lack of awareness of image, poor behaviour-modification strategies), management of social clumsiness, and autism spectrum disorder.
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Biswas, Sayantan. "Progression from Ocular Hypertension into Glaucoma." In Ocular Hypertension - The Knowns and Unknowns [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98886.

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Ocular hypertension (OHT) is characterized by raised intraocular pressure (IOP) &gt;21 mmHg without any visual field (functional) or optic nerve (structural) defect featuring glaucoma. Raised IOP is a major risk factor of glaucoma and a proportion of eyes with OHT progresses into primary open angle glaucoma. Glaucoma is a debilitating disease with potential for blindness if left untreated and associated reduction in the quality of life of the affected individual. It is challenging for the clinicians to decide whether an OHT will progress into glaucoma or not based on the risk factor model of the Ocular hypertension treatment study. Moreover, the question whether only IOP or a myriad of factors like central corneal thickness, baseline IOP, visual field, family history of glaucoma, ocular biomechanics are all important in determining the progression is yet to be answered. The rate of progression is also important and needs analysis for further discussion. Summarizing the landmark studies on ocular hypertension and glaucoma to date are imperative in this regard. This chapter presents the overview of OHT and its possible etiology and pathophysiology, risk factors, clinical tests evaluating OHT eyes and elaborates on the progression of OHT to glaucoma over time in relation to the treatment.
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Cain, Melissa, and Melissa Fanshawe. "Catering for the Specialized Needs of Students With Vision Impairment in Mainstream Classes." In Advances in Early Childhood and K-12 Education. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-2901-0.ch010.

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Thousands of students with vision impairment or blindness attend mainstream schools in Australia. Their experiences depend on multiple pertinent factors, including teachers' understanding of the legal requirements to abide by the inclusive education agenda, schools' understanding of the nature of vision impairments, and the challenges they present to learning. Educators' willingness to take on advice regarding adjustments to the curriculum, assessment, technology, and learning environment are also critical to success for such students. This chapter puts forward the voices of students with vision impairment or blindness to provide a picture of the types of alternative formats used in schools today, including braille and assistive technologies. The voices share how important it is for students to be included in all areas of their education to achieve a sense of belonging and acceptance affording them true inclusion. A list of practical recommendations to assist teachers encourage inclusion academically, socially, and physically is detailed in this chapter.
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Dodson, Paul M. "Diabetes and the eye." In Diabetic Retinopathy: Screening to Treatment (Oxford Diabetes Library). Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198834458.003.0004.

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Diabetes mellitus is still one of the commonest causes of blindness worldwide. The ophthalmic complications of diabetes include diabetic retinopathy (DR), cataracts, primary open angle and neovascular glaucoma, and cranial nerve palsies. Retinovascular disease, including retinal vein and artery occlusion, and non-arteritic ischaemic optic neuropathy are more common in diabetic subjects. DR occurs in approximately 30–35% of diabetic subjects with ethnic differences. The primary abnormalities of DR are capillary basement membrane thickening, such that it becomes porous, and capillary occlusion with resultant retinal ischaemia. In Type 1 diabetes, DR is almost invariable after 15 years of disease duration. In Type 2 diabetes, 20% have retinal signs at diagnosis of diabetes, rising to a prevalence of 60% after 15 years of known disease duration. Major modifiable risk factors for DR include poor glucose and blood pressure control, and increasing lipid levels. In broad terms, Type 1 diabetes is associated with proliferative retinopathy, and Type 2 diabetes with maculopathy.
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Guly, Catherine M., Jane R. MacKinnon, and John V. Forrester. "Diabetic retinopathy." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.1509.

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Blindness is one of the most feared complications of diabetes and although only a small proportion of people with diabetes will become legally blind, a larger number will have significantly impaired vision affecting their daily life. They may have concerns ranging from difficulty reading the telephone directory to loss of their driving licence and hence, restricted independence. The main issues in diabetic retinopathy are identification of those at risk of visually threatening eye disease, addressing modifiable risk factors, and institution of appropriate treatment. All diabetic patients should have access to an effective screening programme. Laser photocoagulation of the retina remains the cornerstone of treatment of sight-threatening diabetic retinopathy, but over the last few years a number of new therapies have been tried and show promise in preventing visual loss from diabetic retinopathy. This chapter will discuss the epidemiology of diabetic retinopathy and the characteristic clinical features and will give an outline of practical management.
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Oza, Meet Ganpatlal, Geeta Rani, and Vijaypal Singh Dhaka. "Glaucoma Detection Using Convolutional Neural Networks." In Handbook of Research on Disease Prediction Through Data Analytics and Machine Learning. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-2742-9.ch001.

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The increase in use of ICT tools and decrease in physical activities has increased the risk of disorders such as diabetes, hypertension, myopia, hypermetropia, etc. These disorders make the person more prone to eye disease such as glaucoma. The actual causes of glaucoma are still unknown. But the study of medical literature reveals that the factors such as intraocular pressure, thyroid, diabetics, eye injuries, eye surgeries, ethnic background, and myopia makes the person more prone to glaucoma. The difficulty in early detection make it an invisible thief of sight. Therefore, it is the demand of the day to design a system for its early detection. The aim of this chapter is to develop a convolutional neural network model “GlaucomaDetector” for detection of glaucoma at an early stage. The evaluation of the model on the publicly available dataset reports the accuracy of 99% for prediction of glaucoma from the input images of retina. This may prove a useful tool for doctors for quick prediction of glaucoma at an early stage. Thus, it can minimize the risk of blindness in patients.
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Manzoor Kadri, Syed, Marija Petkovic, Arshi Taj, and Ailbhe H. Brady. "Leprosy in the Modern Era." In Pathogenic Bacteria. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.91450.

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Leprosy is a chronic infective disease that originates from the presence of pathogen agent Mycobacterium leprae. Mycobacterium leprae was discovered by the Norwegian doctor Gerhard Henrik Armauer Hansen in 1873. For the zoonotic transmission of M. leprae in the US the responsible insects are armadillos (Dasypus novemcinctus). M. leprae is an intracellular microorganism leading to loss of sensibility, innervation, intraepidermal impairment and lesions due to the absence of myelin in Schwann cells. Mycobacterium leprae has high infectivity and low pathogenicity. Incubation period is from 2 to 7 years. Leprosy is an infectious neurodegenerative disorder of the peripheral nervous system. Leprosy is the major cause of human disability due to neurological damage. Leprosy still represents one of the major causes of disabilities in humans. The most common complications are muscle weakness leading to atrophy, bone loss, amputations and blindness. In the case of chronic cutaneous hyperalgesia, there is a local increase in NGF levels. The application of anti-NGF antibodies may be of benefit in treating hyperalgesia in patients with neuropathy and impaired nerve endings. If combined, NGF, NT-3 and glial cell-line derived neurotrophic factor may be sustainable. In over 90% of human individuals an overall genetic resistance has been noted.
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Conference papers on the topic "Blindness – age factors"

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Tullis, Thomas, and Marisa Siegel. "Does ad blindness on the web vary by age and gender?" In CHI '13 Extended Abstracts on Human Factors in Computing Systems. ACM Press, 2013. http://dx.doi.org/10.1145/2468356.2468685.

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Yan, Dongmei, and Jonathan P. Vande Geest. "Microstructural Alterations in the Human Sclera: Do Age and Race Matter?" In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206668.

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Glaucoma, an ocular disease resulting from a loss of retinal ganglion cell function, is the second leading cause of blindness in the world, according to the World Health Organization. Approximately 120,000 are blind from glaucoma, accounting for 9% to 12% of all cases of blindness in the U.S. Earlier studies have suggested that mechanical forces play a critical role in the progression of glaucoma [1–3]. Sigal, Flanagan, et al. studied the influence of varied factors including geometric features and material properties using both generic and individual-specified optic nerve head (ONH) models de
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Myers, Kristin M., Frances Cone, Harry Quigley, Baptiste Coudrillier, and Thao D. Nguyen. "The Inflation Response of Mouse Sclera: Age Effects on the Mechanical Properties of Scleral Tissue." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19289.

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The mouse model offers an opportunity to investigate how alterations to the connective soft tissue contribute to the development of disease through the study of transgenic and diseased mouse strains. For example, by measuring the deformation response of the eye wall to increases in pressure of these different mouse types, the possible role of ocular tissue material properties in glaucomatous damage can be determined. Glaucoma is one of the leading causes of blindness in the United States and in the world with an estimate of 60 million people affected by this year [1]. It is caused by damage to
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