Academic literature on the topic 'Blood-brain barrier'

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Journal articles on the topic "Blood-brain barrier"

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KANDA, Takashi. "Blood-Brain Barrier and Blood-Nerve Barrier." Yamaguchi Medical Journal 54, no. 1 (2005): 5–11. http://dx.doi.org/10.2342/ymj.54.5.

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Shalaby, Mohamed Adel. "Blood-Brain Barrier." Al-Azhar Medical Journal 45, no. 3 (2016): i—vi. http://dx.doi.org/10.12816/0033115.

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Lawther, Bradley K., Sajith Kumar, and Hari Krovvidi. "Blood–brain barrier." Continuing Education in Anaesthesia Critical Care & Pain 11, no. 4 (2011): 128–32. http://dx.doi.org/10.1093/bjaceaccp/mkr018.

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Dunn, Jeff F., and Albert M. Isaacs. "The impact of hypoxia on blood-brain, blood-CSF, and CSF-brain barriers." Journal of Applied Physiology 131, no. 3 (2021): 977–85. http://dx.doi.org/10.1152/japplphysiol.00108.2020.

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The blood-brain barrier (BBB), blood-cerebrospinal fluid (CSF) barrier (BCSFB), and CSF-brain barriers (CSFBB) are highly regulated barriers in the central nervous system comprising complex multicellular structures that separate nerves and glia from blood and CSF, respectively. Barrier damage has been implicated in the pathophysiology of diverse hypoxia-related neurological conditions, including stroke, multiple sclerosis, hydrocephalus, and high-altitude cerebral edema. Much is known about the damage to the BBB in response to hypoxia, but much less is known about the BCSFB and CSFBB. Yet, it
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Koziara, J. M., P. R. Lockman, D. D. Allen, and R. J. Mumper. "The Blood-Brain Barrier and Brain Drug Delivery." Journal of Nanoscience and Nanotechnology 6, no. 9 (2006): 2712–35. http://dx.doi.org/10.1166/jnn.2006.441.

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The present report encompasses a thorough review of drug delivery to the brain with a particular focus on using drug carriers such as liposomes and nanoparticles. Challenges in brain drug delivery arise from the presence of one of the strictest barriers in vivo—the blood-brain barrier (BBB). This barrier exists at the level of endothelial cells of brain vasculature and its role is to maintain brain homeostasis. To better understand the principles of brain drug delivery, relevant knowledge of the blood-brain barrier anatomy and physiology is briefly reviewed. Several approaches to overcome the
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Cho, Choi-Fong. "The Blood-Brain Barrier." Oncology Times 40, no. 2 (2018): 1. http://dx.doi.org/10.1097/01.cot.0000530114.97923.aa.

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Mizee, Mark Ronald, and Helga Eveline de Vries. "Blood-brain barrier regulation." Tissue Barriers 1, no. 5 (2013): e26882. http://dx.doi.org/10.4161/tisb.26882.

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Dobbing, John. "The Blood-Brain Barrier." Developmental Medicine & Child Neurology 3, no. 6 (2008): 610–12. http://dx.doi.org/10.1111/j.1469-8749.1961.tb10430.x.

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Dobbing, John. "The Blood-Brain Barrier." Developmental Medicine & Child Neurology 3, no. 4 (2008): 311–14. http://dx.doi.org/10.1111/j.1469-8749.1961.tb15323.x.

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Daneman, Richard, and Alexandre Prat. "The Blood–Brain Barrier." Cold Spring Harbor Perspectives in Biology 7, no. 1 (2015): a020412. http://dx.doi.org/10.1101/cshperspect.a020412.

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Dissertations / Theses on the topic "Blood-brain barrier"

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Podjaski, Cornelia. "Netrins enhance blood-brain barrier function and regulate immune responses at the blood-brain barrier." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116977.

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During development, netrin guidance cues control cell motility and cell adhesion. Cell-adhesion between endothelial cells at the blood-brain barrier makes the endothelium impermeable to blood-derivatives and immune cells. To establish and maintain this barrier during development, and adulthood, and as well as during disease, brain endothelial cells must develop and sustain these strong adhesive contacts, through expression of tight junction molecules. However, we do not know whether netrins support inter-endothelial cell adhesion at the blood-brain barrier. Given this, we hypothesize that netr
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Zhu, Chunni. "The Blood-brain barrier in normal and pathological conditions." Title page, abstract and contents only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phz637.pdf.

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Bibliography: leaves 318-367. Examines the blood-brain barrier in normal and pathological conditions induced by intravascular and extravascular insults. Intravascular insults were induced by administration of Clostridium perfringens prototoxin; extravascular insults were induced by an impact acceleration model for closed head injury to induce traumatic brain injury. Also examines the integrity of the blood-brain barrier ultrastructurally and by its ability to exclude endogenous and exogenous tracers. Also studies the expression of 2 blood-brain barrier specific proteins, endothelial barrier a
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Brownlees, Janet. "Some enzymes of the blood-brain barrier." Thesis, Queen's University Belfast, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334522.

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Raabe, Rebecca L. "Radiation effects on the blood-brain barrier." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/44779.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2007.<br>Includes bibliographical references (p. 53-56).<br>Selective vascular irradiation enables the critical examination of the vasculature and its role in the onset of late radiation effects. It is a novel approach to expose the endothelial cells to much higher levels of ionizing radiation relative to normal cells by utilizing the boron neutron capture reaction. When boron-containing compounds are restricted to the lumen of the blood vessel, the resulting high-LET alpha and lithium particles can
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Lochhead, Jeffrey James. "Oxidative Stress Alters Blood-Brain Barrier Integrity." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/193873.

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The blood-brain barrier (BBB) is located at the level of the cerebral microvasculature and is critical to maintain central nervous system (CNS) homeostasis. The tight junction (TJ) protein complexes between endothelial cells at the BBB are primarily responsible for limiting paracellular diffusion of substances from the blood to the CNS. The BBB’s functional integrity is compromised in a number of disease states which affect the CNS, suggesting BBB dysfunction causes or contributes to many diseases of the CNS. A common component of most of these diseases is oxidative stres. Oxidative stress is
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Arranz, Gibert Pol. "Blood-Brain Barrier Shuttles: From Design to Application." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/401325.

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The work of this thesis is based on research on peptides able to cross the blood-brain barrier and their use as tools to enable the delivery of drugs into the brain. The blood-brain barrier (BBB) is a permeable but selective barrier that tightly regulates the transport into the central nervous system (CNS). In this regard, therapeutic treatments at the CNS are hampered by the presence of this barrier (BBB). Thus, diverse strategies have been developed to overcome it. Blood-brain barrier shuttles are peptides able to cross this barrier and deliver drugs into the brain. Peptides are privil
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Chen, Bo. "Role of blood-brain barrier leakage during stroke." Diss., [La Jolla] : University of California, San Diego, 2010. http://wwwlib.umi.com/cr/ucsd/fullcit?p3403853.

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Edrissi, Hamidreza. "Blood Brain Barrier Dysfunction in Chronic Cerebral Ischemia." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32531.

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Cerebral small vessel pathology is now known to be associated with the development of cognitive impairment and mild motor impairments such as gait disturbance in a variety of neurodegenerative diseases. This dissertation explores the hypothesis that blood brain barrier dysfunction is an early event in cerebral ischemia and contributes to the development of cerebral small vessel disease (CSVD). A common rodent model of CSVD is permanent bilateral common carotid artery occlusion in the rat. This model was used to study several aspects of the progression of CSVD including the timecourse of blood
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Owe-Young, Robert School of Medicine UNSW. "Kynurenine pathway metabolism at the blood-brain barrier." Awarded by:University of New South Wales. School of Medicine, 2006. http://handle.unsw.edu.au/1959.4/26183.

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A major product of HIV-infected and cytokine-stimulated monocytic-lineage cells is quinolinic acid (QUIN), a neurotoxic metabolite of the kynurenine pathway (KP) of L-tryptophan (L-Trp) metabolism. Despite the large number of neurotoxins found in HIV patients with AIDS Dementia Complex (ADC), only QUIN correlates with both the presence and severity of ADC. With treatment, cerebrospinal fluid (CSF) QUIN concentrations decrease proportionate to the degree of clinical and neuropsychological improvement. As endothelial cells (EC) of the blood-brain barrier (BBB) are the first brain-associated cell
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Bénardais, Karelle [Verfasser]. "Modulation of the blood-brain barrier / Karelle Bénardais." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2013. http://d-nb.info/1037791665/34.

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Books on the topic "Blood-brain barrier"

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Nag, Sukriti. Blood-Brain Barrier,. Humana Press, 2003. http://dx.doi.org/10.1385/1592594190.

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Kobiler, David, Shlomo Lustig, and Shlomo Shapira, eds. Blood—Brain Barrier. Springer US, 2001. http://dx.doi.org/10.1007/978-1-4615-0579-2.

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Barichello, Tatiana, ed. Blood-Brain Barrier. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-8946-1.

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Barichello, Tatiana, ed. Blood-Brain Barrier. Springer US, 2025. https://doi.org/10.1007/978-1-0716-4474-4.

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R, Helio Tomas, ed. The blood brain barrier. Nova Science Publishers, 2008.

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Stone, Nicole, ed. The Blood-Brain Barrier. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2289-6.

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J, Suckling Anthony, Rumsby M. G, and Bradbury M. W. B, eds. The Blood-brain barrier in health and disease. E. Horwood, 1986.

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Montenegro, Pedro A. The blood-brain barrier: New research. Nova Science Publishers, 2011.

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Fricker, Gert, Melanie Ott, and Anne Mahringer, eds. The Blood Brain Barrier (BBB). Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-43787-2.

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A, Neuwelt Edward, ed. Implicationsof the blood-brain barrier and its manipulation. Plenum Medical, 1989.

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Book chapters on the topic "Blood-brain barrier"

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Tran, Nam. "Blood-Brain Barrier." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-57111-9_299.

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Tyrer, Peter J., Mark Slifstein, Joris C. Verster, et al. "Blood–Brain Barrier." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_387.

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Tran, Nam. "Blood-Brain Barrier." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56782-2_299-2.

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Scherrmann, Jean-Michel. "Blood–Brain Barrier." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-36172-2_387.

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Avraham, Shalom, Tzong-Shi Lu, and Hava Karsenty Avraham. "Blood-Brain Barrier." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27841-9_669-2.

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Alemanno, Fernando. "Blood–Brain Barrier." In Biochemistry for Anesthesiologists and Intensivists. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-26721-6_7.

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Leshan, Rebecca, Teri Milner, and Donald W. Pfaff. "Blood-Brain Barrier." In Neuroscience in the 21st Century. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3474-4_129.

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Leshan, Rebecca, Teri Milner, and Donald W. Pfaff. "Blood-Brain Barrier." In Neuroscience in the 21st Century. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4614-6434-1_129-3.

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Leshan, Rebecca, Teresa A. Milner, and Donald W. Pfaff. "Blood-Brain Barrier." In Neuroscience in the 21st Century. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4614-6434-1_129-4.

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Avraham, Shalom, Tzong-Shi Lu, and Hava Karsenty Avraham. "Blood-Brain Barrier." In Encyclopedia of Cancer. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-46875-3_669.

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Conference papers on the topic "Blood-brain barrier"

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Wei, Mian, and Wei Min. "Single-particle imaging of nanomedicine crossing the blood-brain barrier." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2025. https://doi.org/10.1364/omp.2025.om5e.1.

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Current understanding of nanocarrier-brain interaction remains elusive. Based on stimulated Raman scattering, we develop an optical method for imaging nanocarriers in brain tissue with single-particle sensitivity, chemical specificity, and particle counting capability.
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Sun, Yu, Han Zhou, Ziyang Wen, et al. "DL_BBBP: blood-brain barrier permeability prediction based on molecular property using deep learning." In 2024 Fourth International Conference on Biomedicine and Bioinformatics Engineering (ICBBE 2024), edited by Pier Paolo Piccaluga, Ahmed El-Hashash, and Xiangqian Guo. SPIE, 2024. http://dx.doi.org/10.1117/12.3044459.

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Saharov, D. "CREATION OF IN VITRO MODEL OF HUMAN BLOOD-BRAIN BARRIER, COMPLETELY IDENTIFICAL TO REAL BLOOD-BRAIN BARRIER." In 19th SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings. STEF92 Technology, 2019. http://dx.doi.org/10.5593/sgem2019/6.1/s24.019.

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Chaing, Ya-Yu, and Kai-Hong Tu. "In Vitro Microfluidics-based Blood–brain Barrier Model." In 2019 IEEE 14th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2019. http://dx.doi.org/10.1109/nems.2019.8915667.

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Chen, Dechang, Jianwen Fang, and Jiawei Yu. "Predicting Blood-Brain Barrier Penetration by Stochastic Discrimination." In 2008 International Conference on Biomedical Engineering And Informatics (BMEI). IEEE, 2008. http://dx.doi.org/10.1109/bmei.2008.243.

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Guanglei Li, Wei Yuan, and Bingmei M. Fu. "A transport model for the blood-brain barrier." In 2007 IEEE 33rd Annual Northeast Bioengineering Conference. IEEE, 2007. http://dx.doi.org/10.1109/nebc.2007.4413342.

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Li, Guanglei, Melissa J. Simon, Limary Cancel, et al. "Permeability of in vitro blood-brain barrier models." In 2010 36th Annual Northeast Bioengineering Conference. IEEE, 2010. http://dx.doi.org/10.1109/nebc.2010.5458260.

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Choi, James J. "Noninvasive Blood-Brain Barrier Opening in Live Mice." In THERAPEUTIC ULTRASOUND: 5th International Symposium on Therapeutic Ultrasound. AIP, 2006. http://dx.doi.org/10.1063/1.2205480.

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Hynynen, Kullervo. "Notice of Removal: Breaching the blood-brain barrier noninvasively." In 2017 IEEE International Ultrasonics Symposium (IUS). IEEE, 2017. http://dx.doi.org/10.1109/ultsym.2017.8092834.

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Saharov, D. A. "DEVELOPMENT OF CELLULAR MODEL OF HUMAN BLOOD-BRAIN BARRIER." In 19th SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings. STEF92 Technology, 2019. http://dx.doi.org/10.5593/sgem2019/6.1/s25.085.

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Reports on the topic "Blood-brain barrier"

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Aschner, Michael. Blood-Brain Barrier Transport of Uranium. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada433990.

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Aschner, Michael. Blood-Brain Barrier Transport of Uranium. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada412998.

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Aschner, Michael. Blood-Brain Barrier Transport of Uranium. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada422003.

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มณีศรี เลอกรองด์, ศุภางค์, ธนัญญา ทองตัน та อนันต์ ศรีเกียรติขจร. ผลของการได้รับยาพาราเซตตามอลอย่างเรื้อรังที่มีผลต่อการเปลี่ยนแปลง blood-brain barrier : การศึกษาในสัตว์ทดลองและในเซลล์เพาะเลี้ยง : รายงานวิจัยฉบับสมบูรณ์. จุฬาลงกรณ์มหาวิทยาลัย, 2012. https://doi.org/10.58837/chula.res.2012.21.

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ยาพาราเซตามอลเป็นยาที่ได้รับความนิยมใช้กันอย่างแพร่หลาย โดยใช้เป็นยาลดไข้และบรรเทาอาการปวด ผลการวิจัยที่ผ่านมาส่วนใหญ่ยืนยันว่ายาพาราเซตามอลมีฤทธิ์ในการปกป้องเซลล์เมื่อใช้ยาในขนาดเพื่อการรักษา แต่อย่างไรก็ตามในช่วง 10 ปีมานี้เริ่มมีรายงานถึงผลเสียของการใช้ยาชนิดนี้แม้ว่าจะใช้ยาในขนาดเพื่อการรักษา ในหลายระบบ รวมถึงระบบไหลเวียนเลือด และในผลงานวิจัยของคณะเราก่อนหน้านี้พบว่า หนูที่ได้รับยาพาราเซตามอลอย่างเรื้อรังร่วมกับการกระตุ้นให้เกิดปรากฎการณ์คอร์ติคัล สเปรดดิ้ง ดีเปรสชัน มีความไวของเซลล์ประสาทที่บริเวณผิวสมองต่อการกระตุ้นเพิ่มมากขึ้น รวมถึงมีการเปลี่ยนแปลงของปริมาณเลือดในหลอดเลือดสมองด้วย ซึ่ง
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Goldman, Harold, and Robert F. Berman. Regional Blood-Brain Barrier Responses to Central Cholinergic Activity. Defense Technical Information Center, 1991. http://dx.doi.org/10.21236/ada246911.

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Zhang, Luwen. Epstein Barr Virus and Blood Brain Barrier in Multiple Sclerosis. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada593294.

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Zhang, Luwen. Epstein Barr Virus and Blood Brain Barrier in Multiple Sclerosis. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada596844.

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Goldstein, L. B., A. M. Dechovskaia, S. Bullman, K. H. Jones, and A. A. Abdel-Rahman. Daily Dermal Co-Exposure of Rats to DEET and Permethrin Produces Sensorimotor Deficit, and Changes in Blood-Brain Barrier (BBB) and Blood-Testis Barrier (BTB). Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada402081.

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Avraham, Hava. Oxidative Stress Increases the Blood Brain Barrier Permeability Resulting in Increased Incidence of Brain Metastasis in BRCA Mutation Carriers. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada576308.

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Avraham, Hava. Oxidative Stress Increases the Blood Brain Barrier Permeability Resulting in Increased Incidence of Brain Metastasis in BRCA Mutation Carriers. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada560888.

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