Relevant bibliographies by topics / Blood coagulation tests

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Blood coagulation tests'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 August 2024

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Journal articles on the topic "Blood coagulation tests"

1

FUJIKATA, Akira, and Yayoi IKEDA. "Blood coagulation and clotting tests in carp." NIPPON SUISAN GAKKAISHI 51, no. 6 (1985): 933–39. http://dx.doi.org/10.2331/suisan.51.933.

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Yavas, Soner, Selime Ayaz, Serdal Kenan Kose, Fatma Ulus, and Tulga Ahmet Ulus. "Influence of Blood Collection Systems on Coagulation Tests." Turkish Journal of Hematology 29, no. 4 (2012): 367–75. http://dx.doi.org/10.5505/tjh.2012.59254.

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Kozmin, L. D., A. I. Martinov, T. A. Lisitsina, T. M. Reshetnyak, V. I. Lauga, and O. P. Bliznukov. "C-reactive protein prolongs blood coagulation time in phospholipids-dependent coagulation tests." Rheumatology Science and Practice, no. 3 (June 15, 2003): 16. http://dx.doi.org/10.14412/1995-4484-2003-1353.

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Wisser, Dirk, Klaus van Ackern, Ernst Knoll, Hermann Wisser, and Thomas Bertsch. "Blood Loss from Laboratory Tests." Clinical Chemistry 49, no. 10 (October 1, 2003): 1651–55. http://dx.doi.org/10.1373/49.10.1651.

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Abstract Background: Laboratory tests can be an important source of blood loss in hospitals, especially for newborns and patients in intensive care. The aim of this study was to quantify blood loss for laboratory diagnostic tests in a large number of patients in a teaching hospital. Methods: We estimated blood loss by multiplying the number and volumes of sampling tubes collected from 2654 adult inpatients. We compared the number of tests per patient for all inpatients and intensive care unit patients during the first period and again in the same time period 1 year later when cumulative blood-
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Krishnamurthy, Dr Vani, and Rubiya Ahmad. "Comparison of various principles of coagulation tests in handling hemolysed blood samples." Tropical Journal of Pathology and Microbiology 7, no. 4 (August 31, 2021): 188–93. http://dx.doi.org/10.17511/jopm.2021.i04.06.

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Background: Rejection of hemolysed samples for coagulation test is the standard practice.However, when clinicians deal with extremely sick patients where repeat sampling is difficult toobtain, rejection of the sample is a lost opportunity for the lab physician to assist inpatient care.Proceeding with the test and providing a clinically helpful interpretation of the results will ensure theactive participation of the laboratory physician. Different principles of coagulation testing handle thehemolysed samples differently. It is essential to know the best principle to proceed with thehemolysed sa
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KITAJIMA, Isao. "The clinical laboratory tests of blood coagulation and fibrinolysis." Japanese Journal of Thrombosis and Hemostasis 19, no. 4 (2008): 462–66. http://dx.doi.org/10.2491/jjsth.19.462.

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Ferrigno, D., G. Buccheri, and I. Ricca. "Prognostic significance of blood coagulation tests in lung cancer." European Respiratory Journal 17, no. 4 (April 1, 2001): 667–73. http://dx.doi.org/10.1183/09031936.01.17406670.

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Norén, Ingrid, and Astrid Gårde. "Value of Blood Coagulation Tests in Ischemic Cerebral Disease." European Neurology 25, no. 5 (1986): 330–38. http://dx.doi.org/10.1159/000116031.

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Edwards, Richard L., Frederick R. Rickles, Thomas E. Moritz, William G. Henderson, Leo R. Zacharski, Walter B. Forman, C. J. Cornell, et al. "Abnormalities of Blood Coagulation Tests in Patients with Cancer." American Journal of Clinical Pathology 88, no. 5 (November 1, 1987): 596–602. http://dx.doi.org/10.1093/ajcp/88.5.596.

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Larsen, Julie, and Anne-Mette Hvas. "Predictive Value of Whole Blood and Plasma Coagulation Tests for Intra- and Postoperative Bleeding Risk: A Systematic Review." Seminars in Thrombosis and Hemostasis 43, no. 07 (July 18, 2017): 772–805. http://dx.doi.org/10.1055/s-0037-1602665.

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AbstractExcessive perioperative bleeding is associated with increased morbidity and mortality as well as increased economic costs. A range of whole blood laboratory tests for hemostatic monitoring has emerged, but their ability to predict perioperative bleeding is still debated. We conducted a systematic review of the existing literature assessing the ability of whole blood coagulation (thromboelastography [TEG]/thromboelastometry [ROTEM]/Sonoclot), platelet function tests, and standard plasma-based coagulation tests to predict bleeding in the perioperative setting. We searched PubMed and Emba
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Dissertations / Theses on the topic "Blood coagulation tests"

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Hobby, Deanna Jeanne. "A COMPARISON OF ACTIVATED PARTIAL THROMBOPLASTIN TIME OBTAINED BY TWO TECHNIQUES IN PATIENTS FOLLOWING PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY." Thesis, The University of Arizona, 1987. http://hdl.handle.net/10150/291339.

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A descriptive study was conducted to test the null hypothesis: There will be no statistically significant difference between serum activated partial thromboplastin time (aPTT) obtained by two methods; venipuncture and large bore femoral arterial catheter. The convenience sample consisted of seventeen adults who had undergone percutaneous transluminal coronary angioplasty (PTCA) for the treatment of coronary artery disease. After the PTCA procedure, patients returned to an intensive care unit with a femoral intra-arterial catheter in place. Seventeen pairs of serum samples were obtained; one by
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Goldenberg, Neil A. "Development of the clot formation and lysis (CloFAL) global assay and its application to the investigation of bleeding disorders in children and adults /." Connect to abstract via ProQuest. Full text is not available online, 2008. http://proquest.umi.com/pqdweb?did=1545571881&sid=1&Fmt=2&clientId=18952&RQT=309&VName=PQD.

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Thesis (Ph.D. in Clinical Science) -- University of Colorado Denver, 2008.<br>Typescript. Includes bibliographical references (leaves 136-146). Free to UCD Anschutz Medical Campus. Online version available via ProQuest Digital Dissertations;
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Ungerstedt, Johanna S. "Coagulation and inflammation in experimental endotoxemia in vitro and in vivo : monitoring method and effects of nicotinamide /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-477-1/.

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Quaino, Susan Kelly Picoli 1980. "Avaliação da geração de trombina nas fases inicias da sepse em pacientes com nenplasias hematológicas e netropenia febril." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309166.

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Orientador: Erich Vinicius de Paula<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-19T11:03:42Z (GMT). No. of bitstreams: 1 Quaino_SusanKellyPicoli_M.pdf: 2874691 bytes, checksum: aa96cc1f9d7979751213f3bda6ad0681 (MD5) Previous issue date: 2011<br>Resumo: Pacientes com neutropenia febril apresentam risco aumentado de infecções severas e complicações da sepse. A ativação descontrolada da coagulação é uma das características mais marcantes da sepse. O quadro clínico e laboratorial mais característico desta ati
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Nkambule, Bongani Brian. "Platelet flow cytometry and coagulation tests as markers of immune activation in chronic HIV infection." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/20373.

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Thesis (MScMedSc)--Stellenbosch University, 2012.<br>Bibliography<br>ENGLISH ABSTRACT: Background: In the era of antiretroviral therapy (ART), the risk of acquired immune deficiency syndrome (AIDS) related deaths has decreased and people living with Human Immunodeficiency Virus (HIV) now have prolonged life spans. However, an increasing trend of non-AIDS associated deaths has been reported despite adequate control of viral loads. HIV infection is established as a chronic inflammatory condition which is associated with an increased risk for thrombosis. Thus HIV infected patients are at a h
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Marinho, David Silveira. "Exames convencionais da coagulação como variáveis preditoras da indicação de transfusão de plasma fresco congelado durante o transplante de fígado." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-04082015-111311/.

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INTRODUÇÃO: sangramento por coagulopatia é problema comum durante o transplante hepático (TH). O uso adequado da monitorização da coagulação pode reduzir a transfusão de hemocomponentes, como o Plasma Fresco Congelado (PFC). Exames Convencionais da Coagulação (ECC), tais como Tempo de Protrombina (TP) e Tempo de Tromboplastina Parcial Ativada (TTPa), são os testes mais amplamente utilizados para monitorizar a coagulação durante o TH, mas algumas limitações têm sido apontadas acerca do seu uso em pacientes cirróticos. OBJETIVO: investigar o uso de ECC como variáveis preditoras da indicação de t
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Ferreira, Caroline Marcondes. "Potencial de geração de trombina e sua relação com o tempo de protrombina em pacientes com cirrose." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5168/tde-27022019-145125/.

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Introdução: Pacientes com cirrose possuem altos níveis de fator VIII e preservação da trombomodulina (TM) (ativador da proteína C) apesar da redução global nas concentrações dos procoagulantes e anticoagulantes naturais. Isto não é levado em conta no teste de TP/INR, o qual não requer a adição de trombomodulina. Deste modo, o TP/INR não é capaz de demonstrar a magnitude da geração de trombina, em condições similares à que ocorre in vivo. De fato, o teste de TP/INR mede o lado procoagulante e se correlaciona com somente 5% do total de trombina gerada. Nossa hipótese é que a geração de trombina
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Braga, Thalita de Moura Santos. "Tromboelastografia em pacientes estáveis em diálise peritoneal automatizada." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5148/tde-23042018-134702/.

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INTRODUÇÃO: a albumina sérica reduzida em pacientes em diálise peritoneal (DP) é associada à aterosclerose, causa de morte mais comum entre esses pacientes. Semelhantemente à síndrome nefrótica, supõe-se que a perda de proteínas conjuntamente a de fatores de regulação da hemostasia leva ao estímulo da síntese hepática de fatores pró-coagulantes, como o fibrinogênio, deslocando o equilíbrio hemostático em direção ao estado pró-trombótico. Pacientes em DP apresentam valores séricos elevados de marcadores da ativação endotelial e fatores pró-coagulantes, quando comparados a pacientes em hemodiáli
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Vanti, Luiz Augusto. "\"Estudo comparativo do tempo de sangramento avaliado pelo método convencional de Ivy e do tempo de sangramento da mucosa bucal\"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/23/23149/tde-29032007-122523/.

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O ato cirúrgico sempre deve ser precedido de uma avaliação das condições de saúde local e sistêmica do paciente, sendo os exames complementares, o subsídio utilizado para avaliar e confirmar as suspeitas clínicas e hipóteses diagnósticas, adequando o paciente à terapêutica proposta. A literatura é ampla no que diz respeito a testes de hemostasia por meio de diferentes métodos, contudo, não há estudos na literatura revisada que comparem o tempo de sangramento pelo método de Ivy com o tempo de sangramento aferido na mucosa bucal. A proposta deste estudo é de avaliar a técnica de aferição do tem
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Piza, Felipe Maia de Toledo. "Papel da tromboelastometria em pacientes com dengue e trombocitopenia." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-05102016-130612/.

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INTRODUÇÃO: Dengue é uma doença viral prevalente e potencialmente fatal associada à alteração da permeabilidade capilar e coagulopatia. Entretanto, não há estudos concernentes aos achados tromboelastométricos nesta doença. Realizamos o presente estudo para analisar pacientes com dengue e plaquetopenia por meio de um exame rápido, efetivo e a beira leito comparando com os exames convencionais de coagulação. MÉTODOS: Trata-se de um estudo observacional e transversal conduzido entre os dias 6 de abril a 5 de maio de 2015, em São Paulo, Brasil, durante epidemia de dengue. Foi realizado tromboelast
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Books on the topic "Blood coagulation tests"

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Marques, Marisa B. Quick guide to coagulation testing. 2nd ed. Washington, DC: American Association for Clinical Chemistry, 2009.

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Jørgen, Jespersen, Bertina Rogier M, and Haverkate F. 1931-, eds. Laboratory techniques in thrombosis: A manual. 2nd ed. Dordrecht: Kluwer Academic Publishers, 1999.

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L, Evatt Bruce, and Centers for Disease Control (U.S.), eds. Fundamental diagnostic hematology: The bleeding and clotting disorders. 2nd ed. Atlanta, Ga: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, 1992.

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Marques, Marisa B. Quick guide to hemostasis. Washington, DC: American Association for Clinical Chemistry, 2015.

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Jørgen, Jespersen, Bertina Rogier M, Haverkate F. 1931-, European Concerted Action on Thrombosis and Disabilities (Committee), and Commission of the European Communities., eds. ECAT assay procedures: A manual of laboratory techniques. Dordrecht: Kluwer Academic Publishers, 1992.

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Immunoassays in Coagulation Testing. Springer, 2012.

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Marques, Marisa B. Quick Guide to Coagulation Testing:. AACC Press, 2006.

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Bug Club Purple B/2C Yun and the Giant Bird 6-Pack. Pearson Education, Limited, 2010.

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Laboratory Techniques in Thrombosis - A Manual: Second Revised Edition of the Ecat Assay Procedures. 2nd ed. Springer, 1999.

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Lewis, S. M., A. M. H. P. van den Besselaar, and H. R. Gralnick. Thromboplastin Calibration and Oral Anticoagulant Control. Springer Netherlands, 2011.

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Book chapters on the topic "Blood coagulation tests"

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Leavitt, Sarah, Shairko Missouri, Divya Patel, and Corey S. Scher. "Point-of-Care Tests in for Blood Coagulation in the Perioperative Period." In Essentials of Blood Product Management in Anesthesia Practice, 201–15. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-59295-0_21.

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Kent, Amy, Karin Leiderman, Anna C. Nelson, Suzanne S. Sindi, Melissa M. Stadt, Lingyun Xiong, and Ying Zhang. "Studying the Effects of Oral Contraceptives on Coagulation Using a Mathematical Modeling Approach." In Mathematical Modeling for Women’s Health, 83–132. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-58516-6_4.

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AbstractThe use of oral contraceptives (OCs) is known to increase the risk of thrombosis, but the mechanisms underlying this risk and the determinants of the tests that assess this risk are not fully understood. In this study, we used a mathematical model to study the effects of an OC containing levonorgestrel (lev) on blood clotting. Lev is reported to change the plasma levels of blood clotting factors. The mathematical model used in this study simulates coagulation reactions in a small injury under flow, takes clotting factors as inputs, and outputs time courses of the coagulation enzyme thrombin. To study the effects of lev, we created a virtual patient population with factor levels before and after lev use based on published patient data and conducted simulations to predict thrombin response for each individual virtual patient. After analyzing the simulated thrombin, we found that changes in factor levels due to lev increased the amount and speed of thrombin generation for all virtual patients. This suggested that the factor level changes alone can heighten the prothrombotic state of the model system. We extended the model to include generation of the inhibitor activated protein C (APC), so we could test the effects of lev on the systems’ sensitivity to APC. In line with literature reports, the use of lev increased the APC sensitivity, which correlates with increased thrombosis risk.
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Stüber, W., K. Fickenscher, and M. Gerken. "A test kit for the determination of blood coagulation factor XIII based on synthetic peptides." In Peptides, 867–68. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_291.

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Peña, Lea E. Dela. "Hematology: Blood Coagulation Tests." In Basic Skills in Interpreting Laboratory Data, 377–402. ASHP, 2022. http://dx.doi.org/10.37573/9781585286423.017.

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"Chapter 17 Hematology: Blood Coagulation Tests." In Basic Skills in Interpreting Laboratory Data, 393–420. American Society of Health-System Pharmacists, 2017. http://dx.doi.org/10.37573/9781585285495.017.

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Warkentin, T. E. "Acquired coagulation disorders." In Oxford Textbook of Medicine, edited by Chris Hatton and Deborah Hay, 5546–62. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0547.

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Acquired disorders of coagulation may be the consequence of many underlying conditions, and although they may share abnormality of a coagulation test, for example, a prolonged prothrombin time, their clinical effects are diverse and often opposing. General clinical approach: diagnosis—most acquired disorders of coagulation can be identified by screening haemostasis tests, including (1) prothrombin time; (2) activated partial thromboplastin time; (3) thrombin clotting time; (4) fibrinogen degradation products, including (5) the cross-linked fibrin assay (D-dimer); and (6) complete blood count with examination of a blood film. Few bleeding disorders give normal results in all these tests, but disorders predisposed to thrombosis as a result of deficiency of natural anticoagulants (e.g. antithrombin, protein C, and protein S) or certain mutations (e.g. factor V Leiden) must be specifically sought. Treatment—patients with coagulopathies who are bleeding or who require surgery are usually treated with blood products such as platelets and frozen plasma. Other treatments used in particular circumstances include (1) vitamin K—required for the post-translational modification of factors II, VII, IX, and X as well as the anticoagulant factors, protein C, and protein S; (2) cryoprecipitate—used principally for the treatment of hypofibrinogenaemia; (3) concentrates of specific factors—used in isolated deficiencies (e.g. of factors VIII, IX, XI, VIIa, or fibrinogen); (4) antifibrinolytic agents (e.g. ε‎-aminocaproic acid and tranexamic acid); (5) desmopressin (1-deamino-8-d-arginine vasopressin)—increases factor VIII and von Willebrand factor.
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Moore, Gary, and David Gurney. "Bleeding disorders and their laboratory investigation." In Haematology. Oxford University Press, 2021. http://dx.doi.org/10.1093/hesc/9780198826095.003.0014.

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This chapter covers bleeding disorders that arise from hereditary or acquired abnormalities of coagulation factors, von Willebrand factor (VWF), platelets, and blood vessels. It reviews the main laboratory tests available to biomedical scientists in order to identify and characterize bleeding disorders. It also describes the principles and interpretation of coagulation screening tests, platelet function analysis, factor assays and raw data assessment, and inhibitor screening and measurement. The chapter explains that bleeding disorders occur when components of haemostasis are deficient to an extent that confers a tendency to bleed excessively. It emphasizes how the type, site, and severity of haemorrhage can give important clues to whether a haemostatic disorder is present and the areas of haemostasis that are affected.
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Paternoster, Gianluca, Marc O. Maybauer, and Filippo Sanfilippo. "Heparin Anticoagulation for Transcatheter Aortic Valve Implantation on ECMO." In Extracorporeal Membrane Oxygenation, edited by Marc O. Maybauer, 145–52. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780197521304.003.0013.

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Extracorporeal membrane oxygenation (ECMO) is a life-saving intervention option for critically ill patients with cardiac and/or respiratory failure. Worldwide many medical centers started to use ECMO as a rescue treatment option when conventional therapies failed. This chapter describes conventional strategies of anticoagulation for ECMO. Indeed, during ECMO support the continuous flow and the contact between the patient’s blood and nonbiological surfaces such as cannulae or the oxygenator triggers the activation of the coagulation cascade, with formation of clots and consumption of coagulation factors and platelets, leading to peculiar alteration in the hemostasis. Therefore, the activation of coagulation pathways increases the risk of both thrombosis and hemorrhage. Unfractionated heparin remains the anticoagulant of choice for several reasons in patients supported by ECMO, among them the consolidated experience in its use, its low cost, and the presence of protamine, which can be used as an antagonist, even though its use is very rare in ECMO patients. There are different methods of monitoring the anticoagulation level while on heparin infusion for patients supported by ECMO, and among them the two most common are the activated coagulation time (ACT) and the activated partial thromboplastin time (aPTT), while the routine uses of viscoelastic tests and levels of anti-Xa activity are less common.
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Teodorescu, Dana, and Caroline Larkin. "Coagulopathy in Cardiac Surgery: Etiology and Treatment Options." In Cardiothoracic Critical Care, 313–22. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190082482.003.0033.

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This chapter reviews the causes and outlines an approach to the management of coagulopathy following cardiac surgery. Bleeding after cardiac surgery is common and expected up to a rate of 2 mL/kg/h for the first 6 hours. A more significant hemorrhage needs to be investigated and treated. Causes are often multifactorial. It is imperative that surgical causes be excluded early concomitant to providing resuscitation, investigating other medical causes for bleeding, and treating coagulopathy empirically until laboratory testing becomes available. The most frequent causes for coagulopathy post–cardiac surgery are excess heparinization, prolonged cardiopulmonary bypass time, hypothermia, acidosis, and preexisting bleeding diathesis. The management of coagulopathy implies maintenance of the normal physiological conditions for coagulation, reversal of excess heparinization, treatment of hyperfibrinolysis, maintaining normal levels of coagulation factors, and transfusion of platelets if thrombocytopenia or platelet dysfunction occurs. The chapter reviews what is involved in standard laboratory testing (complete blood count, prothrombin time, activated partial thromboplastin time, fibrinogen level, etc.) for coagulopathy. Also discussed is point-of-care testing and how the results from these tests should be interpreted. The chapter details the various blood products that are required in this scenario and suggests doses and transfusion thresholds.
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Jahanbani, Alireza, and Narges Eskandari Roozbahani. "Electrochemical Anticoagulant Method." In Anticoagulation - An Update. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.112524.

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Delving into the science of electrochemistry to test living cells under the influence of metabolic disorders, infections, and injuries has been the focus of a group of interdisciplinary science researchers for decades. Considering that blood is an environment with chemical and physical properties, using non-chemical methods to influence this environment is not out of mind. Due to the presence of ions in the bloodstream and their role in blood coagulation, this passage can be used to obtain desired results in various clinical fields like preventing the clotting of blood. The use of chemical anticoagulants for research and therapeutic purposes is widespread; this group of anticoagulants is replaced under certain conditions due to their side effects. However, the chronic use of some anticoagulants has a potential impact on the future treatment decisions of patients.
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Conference papers on the topic "Blood coagulation tests"

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Chang, Hsueh-Chia. "Micro-Fluidic Technologies for Blood Diagnostics." In ASME 2004 2nd International Conference on Microchannels and Minichannels. ASMEDC, 2004. http://dx.doi.org/10.1115/icmm2004-2315.

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There is considerable market interest for miniature blood diagnostic kits for cholesterol, ovulation, glucose, bacteria, leukemia cells, coagulation tests, drugs etc. However, the presence of blood cells in the blood samples introduces an array of micro-fluidic issues that have become main obstacles to commercialization of these products. We discuss some of these anomalous micro-fluidic features of blood here. Some devices and designs developed at the Notre Dame Center for Micro-fluidics and Medical Diagnostics will be presented as solutions to these micro-fluidic challenges.
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Pathak, Soumi. "Changing trends in coagulation profile of 30 patients undergoing CRS with HIPEC in the peri-operative period." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685386.

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Background: With advent of surgical advancements like HIPEC several unstudied pathophysiological aspects need to be evaluated. We studied the trends in coagulation profile in patients undergoing CRS with HIPEC in the peri-operative period, utilizing Thromboelastography (TEG) in comparison with standard coagulation tests. The utility of TEG as a guide for transfusion of blood products was also evaluated. Materials and Methods: It was a Prospective observational Cohort study which included 30 consecutive patients undergoing CRS with HIPEC at RGCI in 2015. Methodology: Preoperatively standard coa
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Woodhams, B. J., G. Candotti, and P. B. A. Kernoff. "CHANGES IN THE COAGULATION AND FIBRINOLYTIC SYSTEM DURING PREGNANCY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644282.

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Blood samples were collected from 17 volunteers between 8-14, 26-28 and 32-34 weeks of pregnancy. Control samples were collected from 12 non-pregnant female volunteers not using oral contraceptives. All samples were assayed for fibrinopeptide A (FPA), B beta 15-42 and for cross linked D-dimer fragments. A sample was collected for measurement of the in vitro rate of generation of fibrinopeptide A from whole blood (FPA-R).These results are consistent with an increased activation of coagulation (increased FPA and shortened FPA-R) during normal pregnancy, which is compensated for by a concomitant
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Blair, S. D., S. B. Javanvrin, C. N. McCollum, and R. M. Greenhalgh. "THE EFFECT OF EARLY BLOOD TRANSFUSION ON THE OUTCOME OF GASTROINTESTINAL HAEMORRHAGE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644157.

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It has been suggested that mortality due to upper gastrointestinal haemorrhage may be reduced by restricting blood transfusion [1], We have assessed whether this is due to an anticoagulant effect in a prospective randomised trial.One hundred patients with severe, acute gastrointestinal haemorrhage were randomised to receive either at least 2 units of blood during the first 24 hours of admission, or no blood unless their haemaglobin was lessthan 8g/dl or they were shocked. Minor bleeds and varices were excluded As hypercoagulation cannot be measured using conventional coagulation tests, fresh w
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Patrassi, G. M., A. Santarossa, F. Fallo, M. T. Sartori, M. Viero, and A. Girolami. "FACTOR VIII AND FACTOR XII LEVELS IN BORDERLINE HYPERTENSION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644259.

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Borderline hypertension causes mortality and morbidity rates similar to those associated with estabilished hypertension. However, there is no univocal guideline for its therapeutic management. Hypercoagulability in hypertension has been demonstrated. The aim of our study was to evaluate some coagulation factors in agroup of patients affected by borderlinehypertension. The following tests were carried out: PT and PTT, Factor VIII coagulant activity, FVIII antigen and FVIII ristocetin cofactor, Factor XII and Factor XI activities. These tests were selected for their relationship to the contact c
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Andrew, M., B. A. Paes, R. A. Milner, P. J. Powers, M. Johnston, and V. Castle. "THE POSTNATAL DEVELOPMENT OF THE COAGULATION SYSTEM IN THE PREMATURE INFANT." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643606.

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A cohort study was performed to determine the postnatal development of the coagulation system in the “healthy” premature infant. Mothers were approached for consent and a total of 132 premature infants were entered into the study. The group consisted of 64 infants with gestational ages of 34-36 weeks (prem 1) and 68 infants whose gestational age was 33 weeks or less (prem 2). Demographic information and a 2 ml blood sample were obtained on days 1, 5, 30, 90, and 180. Plasma was fractionated and stored at −70°C for batch assaying of the following tests: screening tests, PT, APTT; factor assays
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Palareti, G., M. Maccaferri, M. Poggi, F. Petrini, S. Coccheri, F. Haverkate, F. Montanari, and A. S. Corticelli. "EFFECTS OF GABEXATE MESILATE (FOY), A NEW SYNTHETIC SERINE PROTEASE INHIBITOR, ON BLOOD COAGULATION IN PATIENTS WITH DIC." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644343.

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A pilot open controlled study of FOY was performed in 20 intensive care patients (pts, age 18-63) with DIC diagnosed with standard laboratory criteria (at least 3 of the following: Normotest 70%, fibrinogen 150 mg%, AT III 80%, FDP 20 ug/ml, platelets 150000). Besides the usual treatments, FOY was given to 10 pts (FOY G.) by continuous i.v. infusion (1mg/kg/h) for up to 7 days, while in 10 control pts (Hep.G.) the treatment included low dose s.c. heparin. Blood clotting tests were performed at admission to the study and daily for 7 days; we consider here results obtained at baseline and at the
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David, J. L., M. Lambrichts, and M. T. Closon. "INFRACLINIC ACTIVATION OF PLATELETS AND FIBRIN FORMATION IN CANCER PATIENTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643198.

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Thromboembolism has been frequently reported in cancer patients, mainly in cases with solid tumors. Besides in several animal models, fibrin deposition around the tumor and platelet aggre gates appear to be involved in invasion and metastasis. This study was aimed at evaluating the extent of in vivo platelet activation and fibrin formation in several kinds of human cancer. We excluded from this study patients whose blood was sampled with difficulty as well as those having clinical evidence of thrombosis or embolism, those with thrombocytopenia, increased fibrinogen degradation products or biol
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Schick, K. P., S. Shapiro, G. Tuszynski, and J. Slawek. "SULFATIDES AND GLYCOLIPIDS IN PLATELETS AND ENDOTHELIAL CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643641.

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Sulfatides are sulfated glycolipids which are negatively charged and thought to influence receptor mediated activities. Sulfatides have the capacity to provide a surface for the initiation of in vitro coagulation tests and these acidic lipids represent the potential biological surface for the initiation of the contact and intrinsic systems in vivo. Several sulfatides have been demonstrated in blood platelets. We have investigated sulfatides and other glycolipids in endothelial cells and platelets in order to define the cellular sources for sulfatides that would be available for influencing hem
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Vehar, G. A. "THE PRESENT STATE OF GENE TECHNOLOGY IN THE MANUFACTURE OF HUMAN COAGULATION PROTEINS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644755.

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The production of pharmaceuticals from human plasma that are useful in the treatment of bleeding disorders had its beginning with the development of the Cohn fractionation procedure in the 1940's. As a result of these advances, concentrates became available for the treatment of the hemophilias. Although of low purity and subject to contamination by hepatitis virus, the availability of these compounds resulted in dramatic improvements in the life expectancy and quality of life of afflicted individuals. The numerous problems associated with production of pharmaceuticals from pooled plasma made t
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Reports on the topic "Blood coagulation tests"

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Viksna, Ludmila, Oksana Kolesova, Aleksandrs Kolesovs, Ieva Vanaga, and Seda Arutjunana. Clinical characteristics of COVID-19 patients (Latvia, Spring 2020). Rīga Stradiņš University, December 2020. http://dx.doi.org/10.25143/fk2/hnmlhh.

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Data include following variables: Demographics, epidemiological history, comorbidities, diagnosis, complications, and symptoms on admission to the hospital. Also, body’s temperature and SpO2. Blood cells: white cells count (WBC), neutrophils (Neu), lymphocytes (Ly), eosinophils (Eo) and monocytes (Mo), percentages of segmented and banded neutrophils, erythrocytes (RBC), platelet count (PLT), hemoglobin (Hb), and hematocrit (HCT); Inflammatory indicators: erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP); Tissue damage indicators: alanine aminotransferase (ALT), lactate dehydrog
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