Academic literature on the topic 'Blood outflow'

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Journal articles on the topic "Blood outflow"

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Czosnyka, Marek. "Brain Venous Blood Outflow." Neurocritical Care 31, no. 2 (2019): 249–50. http://dx.doi.org/10.1007/s12028-019-00744-1.

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Lung, Mary A., and James C. C. Wang. "Increase or Decrease in Nasal Airway Resistance Induced by Acetylcholine in Anesthetized Dogs: Vascular Mechanisms." Annals of Otology, Rhinology & Laryngology 103, no. 8 (1994): 646–51. http://dx.doi.org/10.1177/000348949410300812.

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In sodium pentobarbital-anesthetized dogs with spontaneous nasal blood flow or constant-flow vascular perfusion of the nasal mucosa, we measured nasal airway resistance, vascular resistance, and arterial inflow and outflow of the anterior and posterior venous systems. Acetylcholine in low doses (<5 μg/kg per minute, intraarterially) increased nasal airway resistance, and the response was greater in dogs with spontaneous blood flow. Nasal vascular resistance was decreased. However, the posterior venous outflow was increased and the anterior venous outflow was decreased in dogs with constant-
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Arvidsson, D., H. Svensson, and U. Haglund. "Laser-Doppler flowmetry for estimating liver blood flow." American Journal of Physiology-Gastrointestinal and Liver Physiology 254, no. 4 (1988): G471—G476. http://dx.doi.org/10.1152/ajpgi.1988.254.4.g471.

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Whether laser-Doppler flowmetry can be used to monitor liver blood flow was evaluated in a porcine model in which portal venous blood flow was followed indirectly by electromagnetic flowmetry applied to the superior mesenteric artery, and total hepatic venous outflow was measured directly by using an extracorporeal circuit. Hepatic venous outflow at rest was 23.5 +/- 5.7 ml.kg body wt-1.min-1. Occlusion of the hepatic arterial supply reduced hepatic laser-Doppler blood flow to 22%, but hepatic venous outflow only to 80%. Portal venous blood flow remained unchanged or increased slightly. Occlus
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Bateman, Grant. "Hyperemic hydrocephalus: a new form of childhood hydrocephalus analogous to hyperemic intracranial hypertension in adults." Journal of Neurosurgery: Pediatrics 5, no. 1 (2010): 20–26. http://dx.doi.org/10.3171/2009.8.peds09204.

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Object In the majority of adults with idiopathic intracranial hypertension (IIH), there is an elevation in venous pressure associated with a venous outflow stenosis. In about 15% of IIH patients the elevated venous pressure is associated with an elevation in blood flow but little or no evidence of a stenosis. Venostenotic IIH and idiopathic hydrocephalus in children with a normal blood inflow have been shown to be equivalent. The aim of this study was to test whether children with hydrocephalus and an elevated arterial inflow have a vascular pathophysiology that is analogous to the hyperemic f
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HSU, CHEUNG-HWA. "NUMERICAL STUDY FOR FLOW IN PHOENIX LEFT VENTRICULAR ASSIST DEVICE AT PEAK SYSTOLE." Biomedical Engineering: Applications, Basis and Communications 16, no. 06 (2004): 337–43. http://dx.doi.org/10.4015/s1016237204000463.

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The Phoenix left ventricular assist device is driven by pneumatic pump outside a human body to provide air flow in-and-out of a pneumatic diaphragm inside the blood chamber. The inflation and deflation of the diaphragm drives the blood flows. At peak systole, blood flows into aorta with a maximum flow rate both from natural ventricle and artificial ventricle. To assess the critical condition, blood flow pattern of the device at peak systole is studied. We apply the finite volume method with ϰ – ε turbulent model to simulate the steady flow at peak systole. Results provide a comprehension of fl
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Sobota, Lubos, Marek Penhaker, and Jan Kubicek. "Sensor for Blood Outflow in Intravenous Intervention Detection." Acta Mechanica Slovaca 22, no. 1 (2018): 40–45. http://dx.doi.org/10.21496/ams.2018.007.

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de La Torre, Yannick, Stéphane Velasco, Jean-Pierre Tasu, et al. "Impact of the global outflow angle on recanalization after endovascular treatment of middle cerebral artery bifurcation aneurysms." Journal of NeuroInterventional Surgery 10, no. 12 (2018): 1174–78. http://dx.doi.org/10.1136/neurintsurg-2018-013803.

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Background and purposeIntracranial aneurysm recanalization after endovascular treatment (EVT) remains a major problem. The goal of this study was to find new predictive factors of recanalization after EVT of middle cerebral artery (MCA) bifurcation aneurysms.Methods96 MCA bifurcationaneurysms, ruptured or unruptured, treated by EVT between Septembre 2009 and December 2014, were retrospectively included. Clinical parameters and aneurysm characteristics were recorded. From the initial three-dimensional DSA, spatial coordinates found on parent and daughter arteries of MCA bifurcations gave four d
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Reef, Virginia B., Khosrow Lalezari, Job De Boo, Anton Jan van der Belt, Pamela A. Spencer, and Kees J. Dik. "Pulsed-wave Doppler evaluation of intracardiac blood flow in 30 clinically normal Standardbred horses." American Journal of Veterinary Research 50, no. 1 (1989): 75–83. https://doi.org/10.2460/ajvr.1989.50.01.75.

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SUMMARY Pulsed-wave Doppler echocardiography was performed on 30 clinically normal 1-to 6-year-old racing Standardbreds. There were 13 females, 13 geldings, and 4 stallions. Cardiac disease was not detected with M-mode, 2-dimensional real-time or pulsed-wave Doppler echocardiography. Normal flow velocities for right and left atrial outflow, right and left ventricular outflow, the aorta, and pulmonary artery were determined. Peak flow velocities for right and left atrial outflow occurred during the rapid filling phase and were higher toward the mitral valve (mean, 0.70 ± 0.24 m/s) than toward t
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Sowa, Michael G., James R. Mansfield, Gordon B. Scarth, and Henry H. Mantsch. "Noninvasive Assessment of Regional and Temporal Variations in Tissue Oxygenation by Near-Infrared Spectroscopy and Imaging." Applied Spectroscopy 51, no. 2 (1997): 143–52. http://dx.doi.org/10.1366/0003702971939901.

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A combination of near-infrared spectroscopy and discrete wavelength near-infrared imaging is used to noninvasively monitor the forearm during periods of restricted blood outflow (venous outflow restriction) and interrupted blood inflow (ischemia). Multivariate analysis of image and spectral data time courses was used to identify highly correlated spectral and regional domains, while fuzzy C-means clustering of image time courses was used to reveal finer regional heterogeneities in the response of stressed tissues. Localized near-infrared spectroscopy was used to investigate the magnitude of th
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Pranevičius, Mindaugas, Dalius Makackas, Andrius Macas, et al. "The Concept of Venous Steal: The Impact of Vascular Stenosis and Outflow Pressure Gradient on Blood Flow Diversion." Medicina 61, no. 4 (2025): 672. https://doi.org/10.3390/medicina61040672.

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Vascular steal refers to the diversion of blood flow between collateral vessels that share a common inflow restricted by arterial stenosis. Blood is diverted from the high-pressure to the low-pressure, low-resistance system. Vascular steal is associated with anatomical bypass or vasodilation in the collateral network and is called “the arterial steal”. However, we have demonstrated that in the presence of an outflow gradient (e.g., intra-extracranial), blood is shunted to a lower pressure system, a phenomenon we term “venous steal”. Using Thevenin’s equivalent, we generalized the concept of ve
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Dissertations / Theses on the topic "Blood outflow"

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Tavoni, Valentina. "Clinical applicability of an US model to calculate the head blood outflow through collateral vessels." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/8333/.

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Le vene giugulari interne sembrano essere la via principale attraverso cui il sangue defluisce dal cervello verso il cuore, quando siamo in posizione supina. Nel 2008 il professor Paolo Zamboni ha scoperto che una diminuzione dell'attività giugulare può portare allo sviluppo di una condizione emodinamica chiamata CCSVI. Questa può causare ipossia, ritardi nella perfusione cerebrale e riduzione del drenaggio dei cataboliti, oltre ad un'attivazione infiammatoria delle piccole vene e dei tessuti vicini. Questa condizione è stata da subito associata alla sclerosi multipla e su questo argomento s
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Thatte, Suhas Madhusudan. "In Vitro Flow Visualization Study of the Interface between Outflow Graft of Ventricular Assist Device and Aorta." VCU Scholars Compass, 2006. http://scholarscompass.vcu.edu/etd_retro/107.

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Heart transplant is often considered the best treatment for prolonged left ventricular failure. However due to limited donor hearts and ineligibility of some patients to get a transplant, heart assist devices are considered a short/long term option to assist the failing ventricle. Numerous in vitro and animal trials are conducted to study the flow fields in artificial ventricles to avoid hemolysis and thrombosis but the effects of flow fields corresponding to the angle of LVAD insertion into the aorta are often neglected. This experiment uses 30, 60 and 90 degree glass models to signify differ
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Гав'янець, В. В. "Вплив фізичного навантаження на розвиток окольного русла в умовах порушеного відтоку крові". Thesis, Сумський державний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/53761.

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Стінки вен широкої фасції стегна значно товщі за рахунок добре розвиненої зовнішньої оболонки. М'язові вени не мають такої потужної зовнішньої оболонки, у них добре розвинений м'язовий шар. Вени характеризуються добре розвиненим м'язовим шаром і еластичним каркасом.
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Books on the topic "Blood outflow"

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Endlich, Karlhans, and Rodger Loutzenhiser. The structure and function of renal blood vessels. Edited by Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0207.

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The unique structural and functional properties of the renal vasculature are essential in facilitating the massive filtration and reabsorptive processes required for normal renal function. The afferent and efferent arterioles have evolved distinct activation mechanisms that allow an independent regulation of the inflow and outflow resistances of the glomerular capillaries and physiologic control of glomerular capillary pressure and glomerular filtration rate.
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Zhang, Peng-Fei, Yun Zhang, and Siew Yen Ho. Left ventricle: morphology and geometry. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0018.

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The left ventricle is a cone-shaped muscular pump which receives the blood from the left atrium through the inflow tract and ejects it to the aorta through the outflow tract. The double helical myocardial fibre formation is the basis of efficient motion, function, and morphology of the left ventricle. Physiological or pathological changes of these characteristics of the left ventricle can be evaluated by echocardiography. This chapter describes the morphology and geometry of the left ventricle, including the inflow tract, the outflow tract, double helix formation of left ventricle myocardium,
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Bernal, William, and Alberto Quaglia. Normal physiology of the hepatic system. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0173.

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Hepatic blood inflow is from two sources—high-pressure, well-oxygenated blood from the hepatic artery and low-pressure, partly deoxygenated blood from the portal vein. Hepatic inflow is maintained by variation in flows in these two systems. Although less than a third of total blood flow is delivered via the hepatic artery, it is responsible for the majority of hepatic oxygen supply. The liver can be subdivided into eight functionally independent segments, each with its own vascular inflow, outflow, and biliary drainage. The tri-dimensional hepatic microstructure is complex with geographic hete
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Sobol, Julia, and Jack Louro. Obstructive Shock. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0012.

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In the perioperative period, various mechanisms can lead to the development of shock. The type of shock needs to be rapidly elucidated and initial management steps initiated to minimize the time of tissue hypoperfusion. Obstructive shock is caused by physical obstruction of circulation either into or out of the heart. The mechanisms that lead to obstructive shock either prevent blood from entering the right heart during diastole such as a tension pneumothorax or pericardial tamponade, or prevent the heart from ejecting the blood due to a physical obstruction, as in the case of pulmonary emboli
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Karatasakis, G., and G. D. Athanassopoulos. Cardiomyopathies. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199599639.003.0019.

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Echocardiography is a key diagnostic method in the management of patients with cardiomyopathies.The main echocardiographic findings of hypertrophic cardiomyopathy are asymmetric hypertrophy of the septum, increased echogenicity of the myocardium, systolic anterior motion, turbulent left ventricular (LV) outflow tract blood flow, intracavitary gradient of dynamic nature, mid-systolic closure of the aortic valve and mitral regurgitation. The degree of hypertrophy and the magnitude of the obstruction have prognostic meaning. Echocardiography plays a fundamental role not only in diagnostic process
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Book chapters on the topic "Blood outflow"

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Kwack, JaeHyuk, Soonpil Kang, Geetha Bhat, and Arif Masud. "Time-Dependent Outflow Boundary Conditions for Blood Flow in the Arterial System." In Advances in Computational Fluid-Structure Interaction and Flow Simulation. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-40827-9_28.

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Ramalho, Susana, Alexandra B. Moura, Alberto M. Gambaruto, and Adélia Sequeira. "Influence of Blood Rheology and Outflow Boundary Conditions in Numerical Simulations of Cerebral Aneurysms." In Lecture Notes on Mathematical Modelling in the Life Sciences. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4178-6_6.

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Willans, S. M., S. P. F. Hughes, and I. D. McCarthy. "A Multicapillary Distributed Model of Blood-Bone Exchange to Analyse Multiple Tracer Outflow Dilution Data." In Bone Circulation and Bone Necrosis. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-73644-5_6.

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Elawady, Khaled, and Saqeb Beig Mirza. "Review of Compartment Syndrome." In A Comprehensive Review of Compartment Syndrome [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99996.

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Compartment syndrome is a painful condition, caused by increased pressure in a closed muscular compartment. A compartment is a group of muscles enclosed in fascia and septa of connective tissue, which separates different muscle groups. The chambers created receive their blood supply through the arteries. As the pressure builds in the closed space, the blood supply to muscles enclosed decreases. Normal compartment pressure allows blood to flow in and then venous outflow to exit the compartment. However, with increased pressure in the compartment, the arterial flow is impaired. Subsequently, ven
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Wu, Huijuan, and Teresa C. Chen. "Angle and Nonpenetrating Glaucoma Surgery." In Complications of Glaucoma Surgery. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780195382365.003.0011.

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The outflow of aqueous via the anterior chamber angle is a constant process. The aqueous is formed by the ciliary processes and then passes through the pupil from the posterior chamber to the anterior chamber (Figure 2.1). About 83%–96% of the aqueous finally exits the eye into the anterior chamber angle via the trabecular meshwork—Schlemm’s canal—venous system (i.e., the conventional or canalicular outflow pathway). The other 5%–15% of aqueous outflow occurs via uveoscleral outflow (i.e., the unconventional or extracanalicular outflow pathway), with aqueous passing through the ciliary muscle
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Abqari, Shaad. "Right Ventricular Outflow Tract Stenting." In Congenital Heart Defects - Recent Advances [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.105077.

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RVOT stenting has gained popularity over the last decade. Conventional treatment of choice in children with cyanotic heart defect with decreased pulmonary blood flow has always been the systemic to pulmonary arterial shunt, but lately, many centres are opting for RVOT stenting as the first choice of palliation. It is associated with fewer post-procedural complications and helps in a more physiological growth of pulmonary arteries, which can significantly impact the definitive repair at later date. Normally, RVOT stenting is performed in the early newborn period but it is not unusual to be done
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Guyenet, P. G. "Role of the Ventral Medulla Oblongata in Blood Pressure Regulation." In Central Regulation of Autonomic Functions. Oxford University PressNew York, NY, 1990. http://dx.doi.org/10.1093/oso/9780195051063.003.0009.

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Abstract The sympathetic vasomotor outflow is composed of a series of parallel and differentially regulated efferent pathways that control the cardiac output and the vascular tone of somatic and visceral structures. These pathways are thought to be organized in a highly specific fashion. For example, it is currently believed that specific sets of sympathetic preganglionic neurons may regulate the activity of muscle vasoconstrictor sympathetic postganglionic fibers and other sympathetic preganglionic neurons may control cutaneous vasoconstrictor postganglionic neurons (see Chapter 18).
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Teixeira, Camila, and Steven Minear. "Intraocular Pressure." In Basic Anesthesia Review, edited by Alaa Abd-Elsayed. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197584569.003.0097.

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Abstract Subtle intraocular pressure (IOP) elevation during surgery plays a significant role in the pathogenesis of perioperative ocular morbidity, particularly in patients with preexisting eye disease. The balance between the aqueous humor production and outflow rate is the main predictor of IOP. Resistance to the aqueous humor outflow, as presented in glaucomatous patients, can rapidly increase IOP and impair blood flow to retina and nerve optic. Perioperative visual loss (POVL) is an uncommon but catastrophic complication. Surgical or anesthetic features that combine either to decrease the
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Gimson, Alexander. "Vascular disorders of the liver." In Oxford Textbook of Medicine, edited by Jack Satsangi. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0330.

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The liver’s complex blood supply and high metabolic activity may be affected in a number of clinical situations when there is reduced splanchnic inflow and impaired hepatic venous outflow. Budd–Chiari syndrome is caused by obstruction to hepatic venous outflow, usually by thrombosis within the hepatic veins. Causes include myeloproliferative disease, malignancy, and hypercoagulable states. Presentation may be acute, subacute, or chronic, and the diagnosis requires consideration in any patient presenting with acute liver failure, acute hepatitis, or chronic liver disease. Diagnosis is made by D
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Ferguson, Kris, and Amol Soin. "Barbiturates." In Basic Anesthesia Review, edited by Alaa Abd-Elsayed. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197584569.003.0073.

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Abstract Thiopental is the prototypical barbiturate intravenous induction agent. It has a rapid onset of action and quick termination of action. Termination of action is due to redistribution. It lacks analgesic properties, therefore airway manipulation can precipitate laryngospasm. Barbiturates have minimal impact on blood pressure and cardiac output; however, in patients with hypovolemia or shock, barbiturates can precipitate significant hypotension due to a decrease in sympathetic outflow. Barbiturates are contraindicated in patients with acute intermittent porphyria.
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Conference papers on the topic "Blood outflow"

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Zhingre Sanchez, Jorge D., Lars M. Mattison, Michael G. Bateman, and Paul A. Iaizzo. "Computational Simulations of Ventricular Outflow Tract Obstructions Associated With Varied Replacement Valve Geometries." In 2018 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dmd2018-6916.

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Transcatheter replacement therapies for the atrioventricular (AV) valves are considered as the next frontier for the treatment of valvular regurgitation. The AV valves, tricuspid and mitral, are the regulators of blood flow from the atria into the ventricles. During diastole, blood flows through the open tricuspid and mitral valves to fill the right and left ventricles, respectively. During systole, the ventricles contract, closing the AV valves, and forcing the blood to exit through their respective ventricular outflow tracts (VOTs) to the arterial circulations. Although the current gold stan
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Liu, Aiping, Ruikang Wang, Kent Thornburg, and Sandra Rugonyi. "Wall Motion Influences Flow Pattern in the Outflow Tract of the Chick Embryonic Heart Tube." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19484.

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The outflow tract (OFT) of the chick embryonic heart offers a good model system to study the association between blood flow dynamics and cardiac morphogenesis in early heart development. At early stages, the chick heart is a looped tube without valves. The OFT, the distal region of the heart, functions as a primitive valve [1]. The OFT is a slightly curved tube with three-layered wall (Fig. 1 (A) and (B)): the myocardium, an external muscle layer that actively contracts; the endocardium, an inner endothelial layer that directly contacts blood; in between the cardiac jelly, an extracellular mat
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Menon, Prahlad G., Nikola Teslovich, Chia-Yuan Chen, Fotis Sotiropoulos, Akif Undar, and Kerem Pekkan. "Device Specific Aortic Outflow Cannula Jets Studied Using 2D PIV and High-Performance 3D CFD Simulation." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80454.

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In the US, approximately 1 in 100 children are born with a clinically significant congenital heart defect (CHD). The palliative repair of these defects requires complex biventricular and univentricular surgical operations in newborns often smaller than 2 kg. However, recovery after neonatal intervention remains suboptimal 1. A major component of these surgeries is the cardiopulmonary by-pass (CPB) procedure which if prolonged can potentially lead to neurological complications and developmental defects in a young patient. During CPB, tiny aortic cannulae (2–3 mm inner diameter), with micro-scal
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Ma, Zhenhe, Linlin Du, Qiaoyun Wang, et al. "Changes in strain and blood flow in the outflow tract of chicken embryo hearts observed with spectral domain optical coherence tomography after outflow tract banding." In SPIE BiOS, edited by Andrew M. Rollins, Cecilia Lo, and Scott E. Fraser. SPIE, 2013. http://dx.doi.org/10.1117/12.2002999.

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Kaufmann, T. A. S., T. Schmitz-Rode, A. Moritz, and U. Steinseifer. "EFFECT OF OUTFLOW CANNULA PLACEMENT AND PULSATILITY OF BLOOD PUMPS ON CEREBRAL BLOOD FLOW AND WALL SHEAR STRESS DURING CARDIAC ASSIST." In 10th World Congress on Computational Mechanics. Editora Edgard Blücher, 2014. http://dx.doi.org/10.5151/meceng-wccm2012-18131.

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Carson, James P., Monique Y. Rennie, Michael Danilchik, Kent Thornburg, and Sandra Rugonyi. "A chicken embryo cardiac outflow tract atlas for registering changes due to abnormal blood flow." In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2016. http://dx.doi.org/10.1109/embc.2016.7590929.

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Yang, Ning, Steven Deutsch, Eric G. Paterson, and Keefe B. Manning. "Numerical Study of Blood Flow at the End-to-Side Anastomosis of a Left Ventricular Assist Device for Adult Patients." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192745.

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Ventricular assist devices (VADs) have been used for years in adult patients with end-stage heart failure, during bridge-to-transplant, and they have recently shown promise in aiding in myocardial recovery [1]. While the fluid mechanics within VADs has been studied extensively [2], an area which must be more adequately addressed is the outflow cannula attached as an end-to-side anastomosis to the aorta. This attachment may lead to unnaturally high and low shear stresses, turbulence, flow separation, and stagnant flows. As a result, platelet activation and thrombus formation may occur. May-Newm
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Yasuda, Kazuma, and Shigehiko Kaneko. "Numerical Simulation of Pulse Wave Propagation in Arteries With Structured-Tree Outflow Conditions." In ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/detc2012-71013.

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When constructing the one-dimensional systemic artery tree, the Windkessel model based on parameters describing the total resistance and compliance is generally applied as outflow boundary conditions. However, the Windkessel model does not include wave propagation effects, and moreover, it is not obvious how the parameters should be estimated. Hence, the main purpose of this study is to develop an outflow boundary condition based on the underlying physiology of the arterioles, enabling the prediction of blood flow and pressure in the systemic arteries including the arterioles. The obtained num
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Rennie, Monique Y., Michael Danilchik, Kent L. Thornburg, and Sandra Rugonyi. "Hemodynamic Forces Regulate Collagen Deposition in the Embryonic Chicken Outflow Tract." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14299.

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Alterations in blood flow at early embryonic stages can lead to detrimental remodeling and heart defects, but these structural adaptations are not well understood. We hypothesize that deposition of collagens will be increased as shear stress is increased — leading to a stiffer wall. To test this hypothesis a suture (OTB) was tightened around the outflow tract (OFT) of stage HH18 chick embryos for 24 hours to reduce cross sectional area of the lumen. Sham and OTB embryos were immunostained for collagen I, III, VI and XIV, imaged with confocal microscopy, and staining was quantified by grayscale
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Tang, Ruixuan, Xuanming Zhao, Junshi Wang, Justin Hyde, Bradley Kesser, and Haibo Dong. "Effect of Diameter Size on the Unsteady Characteristics of Pulsatile Flow in Curved Human Blood Vessel." In ASME-JSME-KSME 2019 8th Joint Fluids Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/ajkfluids2019-5227.

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Abstract Pulse-synchronous tinnitus (PST) has been linked to multiple anatomical variants of the venous outflow tract, including transverse sinus (TS) stenosis and sigmoid sinus (SS) dehiscence. It is unknown if the size of diameter in the TS part at the symptomatic side will result in PST. In this study, a combined experimental and computational approach is adopted to study the blood flow during PST. A parametric study is performed on the diameter size of one PST patient at the symptomatic side. A Reynold-averaged-Navier-Stokes (RANS) flow solver is employed in ANSYS Fluent to simulate the sy
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