Academic literature on the topic 'Blood transfusion'
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Journal articles on the topic "Blood transfusion"
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Nigam, A., A. Prakash, and P. Saxena. "Blood Transfusion in Obstetrics." Kathmandu University Medical Journal 11, no. 4 (2015): 355–59. http://dx.doi.org/10.3126/kumj.v11i4.13484.
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Transfusion of blood and blood components is a common practice in obstetric wards but it is not without risk. The incidence of transfusion reactions varies from 4 in every hundred transfusions for non-haemolytic reactions to one in every 40,000 for haemolytic transfusion reactions. The physiological basis of blood transfusion is outlined in this article. Most of the donated blood is processed into components: packed red cells (PRBCs), platelets, and fresh frozen plasma (FFP) or cryoprecipitate. Various alternatives to blood transfusion exist and include autotransfusion, pre-autologous blood storage, use of oxygen carrying blood substitutes and intraoperative cell salvage. Despite the risks associated with transfusions, obstetricians are frequently too aggressive in transfusing blood and blood products to their patients. Acute blood loss in obstetrics is usually due to placenta praevia, postpartum blood loss and surgery related. An early involvement of a consultant obstetrician, anaesthetist, haematologist and the blood bank is essential. There are no established criteria for initiating red cell transfusions and the decision is purely based on clinical and haematological parameters, which have been discussed along with the general principles of blood transfusion in obstetrics and some practical guidelines.Kathmandu Univ Med J 2013; 11(4): 355-359
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Rajput, Anupriya, Prempati Mayangalambam, and SP Subashini. "Blood Donation and Transfusion." Indian Journal of Medical and Health Sciences 10, no. 1 (2023): 41–47. http://dx.doi.org/10.21088/ijmhs.2347.9981.10123.6.
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Blood donation is a vital part of worldwide healthcare. It relates to blood transfusion as a life-sustaining and life-saving procedure as well as a form of therapeutic phlebotomy as a primary medical intervention. Over one hundred million units of blood are donated each year throughout the world. Blood transfusion from one person to another is a special procedure used by doctors in medical procedures that involve patients with the need of blood. The only authorized person that can allow a blood transfusion is if he or she is a healthcare provider (Getting a Blood Transfusion). The procedure of course cannot be done by anyone that does not have possession of a medical degree where they are permitted legally to prescribe or give a blood transfusion to a patient. Blood transfusions are used for serious injuries, surgery, and when a person can’t make enough blood. Doctors use blood transfusions for surgeries where a patient could eventually lose blood during the medical procedure.
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Katz, Elizabeth A. "Blood Transfusion." AACN Advanced Critical Care 20, no. 2 (2009): 155–63. http://dx.doi.org/10.4037/15597768-2009-2007.
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The effectiveness of transfusions is often compromised by adverse reactions. Common transfusion reactions (hemolytic transfusion reactions, transfusion-related acute lung injury, transfusion-associated circulatory overload, transfusion-related immunomodulation) are reviewed, including pathogenesis, clinical and laboratory manifestations, and treatment. In addition, artificial blood substitutes are discussed as a way to mitigate the risk of transfusion-related morbidity and mortality.
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Salsabila, Tasya Radhia, Harapan Parlindungan Ringoringo, Roselina Panghiyangani, Edi Hartoyo, and Rahmiati Rahmiati. "Prevalensi Reaksi Transfusi Darah Penderita Talasemia Beta Mayor yang Bergantung Transfusi di RSD Idaman Banjarbaru Tahun 2020-2021." Homeostasis 5, no. 1 (2022): 35. http://dx.doi.org/10.20527/ht.v5i1.5163.
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Abstract: Patients with beta thalassemia major require regular and routine blood transfusions throughout life to maintain hemoglobin levels in order to survive. Blood transfusion in patients with beta thalassemia major who depend on transfusion can cause side effects and unwanted transfusion reactions. Transfusion reactions range from mild to life-threatening. The purpose of this study was to obtain data on the prevalence of transfusion reactions in transfusion-dependent beta thalassemia patients at Idaman Hospital Banjarbaru in 2020-2021. This study is a descriptive study that was taken retrospectively using patient medical record data. The results showed that there were 131 data on blood transfusion reactions of patients with beta thalassemia major who were dependent on transfusion from a total of 1591 data on transfusion at Idaman Hospital Banjarbaru for the period October 2020 - September 2021 with a prevalence of 8.2%. Moderate-severe transfusion reactions were the most common type, with 90 blood transfusion reactions (68.7%). The five main symptoms of a blood transfusion reaction that occur are fever, chills, pruritus, angioedema, and urticaria. All transfusion reactions that occurred were acute transfusion reactions and used PRC blood components. Keywords: beta thalassemia major, transfusion dependent, blood transfusion, transfusion reactions, PRC (Packed Red Cells) Abstrak: Pasien talasemia beta mayor memerlukan transfusi darah secara teratur dan rutin sepanjang hidup untuk mempertahankan kadar hemoglobin guna bertahan hidup. Transfusi darah pada penderita talasemia beta mayor yang bergantung transfusi dapat menimbulkan efek samping dan reaksi transfusi yang tidak diinginkan. Reaksi transfusi tersebut dari ringan sampai mengancam jiwa. Tujuan penelitian ini adalah memperoleh data prevalensi reaksi transfusi penderita talasemia beta mayor yang bergantung transfusi di RSD Idaman Banjarbaru Tahun 2020-2021. Penelitian ini merupakan penelitian deskriptif yang diambil secara retrospektif menggunakan data rekam medis pasien. Hasil penelitian menunjukkan bahwa terdapat 131 data reaksi transfusi darah penderita talasemia beta mayor yang bergantung transfusi dari total 1591 data transfusi di RSD Idaman Banjarbaru periode Oktober 2020 – September 2021 dengan prevalensi sebesar 8,2%. Reaksi transfusi sedang-berat merupakan jenis yang paling banyak terjadi sebanyak 90 reaksi transfusi darah (68,7%). Lima gejala utama dari reaksi transfusi darah yang terjadi adalah demam, menggigil, pruritus, angioedema, dan urtikaria. Semua reaksi tranfusi yang terjadi adalah reaksi transfusi akut dan menggunakan jenis komponen darah PRC. Kata-kata kunci: talasemia beta mayor, bergantung transfusi, transfusi darah, reaksi transfusi, PRC (Packed Red Cells)
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Desmond, M. J. "‘Bloody easy’; Blood Transfusions, Blood Alternatives and Transfusion Reactions; A Guide to Transfusion Medicine." British Journal of Anaesthesia 92, no. 5 (2004): 781. http://dx.doi.org/10.1093/bja/aeh551.
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Roseff, Susan D. "BLOODY EASY: BLOOD TRANSFUSIONS, BLOOD ALTERNATIVES & TRANSFUSION REACTIONS: A GUIDE TO TRANSFUSION MEDICINE." Transfusion 44, no. 6 (2004): 941. http://dx.doi.org/10.1111/j.1537-2995.2004.04049.x.
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Smith, Jasmine, Martha Sola-Visner, Henry Feldman, et al. "Retrospective Review of Transfusion Practices in a Single Neonatal Intensive Care Unit (NICU) Compared to Recent Transfusion Guidelines." Blood 138, Supplement 1 (2021): 2145. http://dx.doi.org/10.1182/blood-2021-154475.
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Abstract Background Platelet and packed red blood cell (pRBC) transfusion practices for preterm infants vary significantly worldwide. Recent randomized trials of preterm infants receiving platelet or pRBC transfusions have not shown any benefit with higher compared to lower transfusion thresholds. In the recent PlaNeT2 study published in January 2019, infants receiving platelets at higher thresholds had significantly higher rates of death and major bleeding. These findings raise concern about transfusing adult platelets into a delicately balanced neonatal hemostatic system with relatively hypofunctional platelets as a potential etiology of this multifactorial outcome. In this retrospective review, we aimed to review transfusion practices and outcomes, including thrombosis, in the neonatal intensive care unit (NICU) at the University of Arizona, Tucson in comparison to the PlaNeT2 study. Methods After Institutional Review Board approval, we reviewed the electronic medical records of all neonates born at < 32 weeks gestation in the NICU or transferred to the NICU within 48 hours of birth between January 1, 2018 and December 31, 2019, corresponding to one year pre- and one year post-publication of the PlaNet2 study. For each patient record reviewed, we collected demographics, reviewed whether transfusions occurred, and documented pre-transfusion hemoglobin, platelet count, international normalized ratio, fibrinogen activity level, and clinical outcomes. We recorded the number of transfusions of each product, clinical central lines placed, and imaging studies performed to detect thrombosis. These data were analyzed using descriptive analysis. Results There were 127 neonates born <32 weeks gestation, all of whom were analyzed. Twenty-eight (35%) of neonates were born at <27 weeks' gestation and twenty-two (17%) were <1500 g at birth and were considered high risk infants. Seventy three percent of these patients were intubated at some point during their NICU admission. The majority of patients had bronchopulmonary dysplasia (63%). Ten patients developed necrotizing enterocolitis (7.8%), 28 had presumed or confirmed sepsis (22%), 52 had congenital heart disease (41%), and 12 had retinopathy of prematurity (9.4%). During the two-year period of this review, 60% of patients had at least one pRBC transfusion, 13% of patients had at least one platelet transfusion, and 6% of patients had at least one fresh frozen plasma (FFP) transfusion. A total of 35 platelet, 370 pRBC, and 11 FFP transfusions were administered with a mean total of 3.3 total transfusions per patient. The mean and median pre-transfusion platelet counts were 79,300/uL and 52,000/uL, respectively. The mean and median pre-transfusion hemoglobin values were 12.1 g/dL and 12.2 g/dL, respectively. Only two of 35 platelet transfusions were given after the publication of the PlaNeT2 study in January 2019; however, both transfusions were given for neonates with pre-transfusion platelet counts >50,000/uL. There were no arterial or venous thrombosis events noted in our population even though 108 patients (85%) had a peripherally inserted central catheters for an average of 12 days, 32 (25%) had umbilical arterial catheters for an average of 7 days, and 66 (52%) had umbilical vein catheters placed for an average of 6 days. Conclusions The majority of transfusions given to neonates born at <32 weeks gestation at the University of Arizona, Tucson institution over a two-year retrospective study period were pRBC transfusions with an incidence of 0.6 followed by platelet transfusions (incidence of 0.13) and FFP. Platelet transfusion practices changed drastically following publication of the PlaNet2 study, with only 2 of 35 (5.7%) platelet transfusions given after the publication of this study. No thrombotic events were documented in the study population despite a high prevalence of central venous lines and a mean pre-platelet transfusion threshold of 79,300/uL. Transfusion practice guidelines can affect clinical practices in the NICU and can potentially minimize risks. Larger prospective studies are needed to evaluate risk of thrombosis related to adult platelet transfusions given to neonates. Disclosures No relevant conflicts of interest to declare.
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Iqbal, Uzma. "Assessment of Knowledge and Practice regarding Blood Transfusion among Staff Nurses." Trends in Nursing Administration & Education 10, no. 01 (2021): 7–13. http://dx.doi.org/10.24321/2348.2141.202102.
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Background: Blood transfusion is the transfusing of a compatible donor’s whole blood or any of its components to the recipient to correct/ treat any related clinical condition. The transfusion of blood products is essential for restoring the body’s oxygen transport capacity, or replenishing lost or depleted blood components in various medical conditions. Objectives: To assess knowledge and practice score regarding blood transfusion among staff nurses and to identify the association of knowledge score and practice score with selected demographic variables. Methodology: A descriptive research design that involved convenience sampling technique to collect data from the 60 staff nurses working at Sher-i-Kashmir Institute of Medical Sciences, Kashmir, using a “self-structured knowledge questionnaire and practice checklist”. Results: The study revealed that most of the staff nurses, i.e. 53.3%, had fair knowledge, 41.7% had poor knowledge, and only 5% of staff nurses had good knowledge regarding blood transfusion. The mean ± SD knowledge score of the staff nurses was 23.516 ± 4.59. Most of the staff nurses, i.e. 66.7%, had satisfactory practice, and 33.3% had unsatisfactory practice. The mean ± SD practice score of staff nurses regarding blood transfusion was 49.26 ± 6.40. A statistically significant association was found between nurses’ knowledge and demographic variables viz., age, professional qualification, clinical experience, the approximate number of blood transfusions performed in past 6 months, and in-service training programme attended regarding blood transfusion, and practice with demographic variables, viz., gender and clinical experience at p ≤ 0.05. Conclusion: The study concluded that deficiency of knowledge among nurses regarding blood transfusion threatens patients’ safety, and may also put patients in life-threatening conditions.
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Pashkova, I. A., V. A. Porkhanov, I. S. Polyakov, et al. "BLOOD TRANSFUSION IN LUNG OPERATIONS." Grekov's Bulletin of Surgery 175, no. 3 (2016): 47–53. http://dx.doi.org/10.24884/0042-4625-2016-175-3-47-53.
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The authors admit the risks of blood transfusion, as well as the fact that the blood is a limited resource. These conclusions became the basis of the research in order to make an analysis and develop transfusion strategies in the hospital. An assessment of blood components application was performed in specific cases. There was changed the management of blood transfusion and further monitoring was continued. It was shown that the efficacy of an introduction of a new transfusion strategy confirmed the decrease of the rate of inappropriate blood transfusions, the quantity of patients who obtained transfusion of allogenic blood components and as a result, the new methods reduced the number of blood transfusions.
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Jayaprawira, Dentiama. "Strategi penatalaksanaan dan pencegahan Transfusion-Associated Circulatory Overload (TACO): tinjauan pustaka." Intisari Sains Medis 14, no. 2 (2023): 568–75. http://dx.doi.org/10.15562/ism.v14i2.1765.
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Background: Transfusion-associated circulatory overload (TACO) is a serious complication after blood transfusion. Although the incidence of TACO ranges from 0.1% to 10% of all blood transfusions, the mortality rate is quite high, up to 11 cases per 100,000 transfusions. This literature review aims to identify strategies for managing and preventing TACO in daily clinical practice. Methods: This literature review was conducted by searching studies on online databases in the form of PubMed, Cochrane Library, and Google Scholar using the keywords “Transfusion-Associated Circulatory Overload” (TACO)”, “blood transfusion”, “pathophysiology”, “management”, “prevention”. Appropriate studies then carried out a narrative synthesis analysis. Results: In TACO, excess fluid causes pulmonary edema, which can lead to respiratory distress. The main mechanism of TACO is hydrostatic pulmonary edema, in which the accumulation of fluid in the pulmonary capillaries then causes an increase in hydrostatic pressure. The management of TACO includes immediately stopping the administration of transfusion products and supportive therapy in the form of supplemental oxygen administration and administration of diuretics such as furosemide. In contrast, prevention of TACO can be done with a restrictive transfusion strategy, rules for using single-dose red blood cell transfusions, identification of high-risk patients using algorithms or checklists, intensive monitoring of at-risk patients, administration of blood product infusions at a slow rate, and use of diuretic drugs preemptive in at-risk patients. Conclusion: The main key to the management of TACO is to prevent the further formation of pulmonary edema by stopping the administration of transfusions and giving oxygen and diuretics. Meanwhile, preventive measures can be taken by restricting blood product administration, identifying high-risk patients and pre-emptive diuretic administration. Latar belakang: Transfusion-associated circulatory overload (TACO) merupakan salah satu komplikasi serius pasca transfusi darah. Meskipun insiden TACO berkisar antara 0,1% hingga 10% dari semua transfusi darah., angka mortalitasnya tergolong cukup tinggi yakni hingga 11 kasus per 100.000 transfusi. Tinjauan pustaka ini bertujuan untuk mengetahui strategi penatalaksanaan dan pencegahan TACO dalam praktik klinis sehari-hari. Metode: Tinjauan pustaka ini dilakukan dengan pencarian studi pada basis data online berupa PubMed, Cochrane library, dan Google Scholar dengan menggunakan kata kunci “Transfusion-Associated Circulatory Overload” “(TACO)”, “blood transfusion”, “pathophysiology”, “management”, “prevention”. Studi yang sesuai kemudian dilakukan analisis sintesis secara naratif. Hasil: Pada TACO terjadi kelebihan cairan yang menimbulkan edema paru yang dapat berujung pada distres nafas. Mekanisme utama terjadinya TACO adalah edema pulmoner hidrostatik, dimana akumulasi cairan pada kapiler pulmoner kemudian menyebabkan peningkatan tekanan hidrostatik. Penatalaksanaan TACO meliputi pengehentian pemberian produk transfusi dengan segera dan terapi suportif berupa pemberian oksigen supplemental serta pemberian diuretik seperti furosemide. Sedangkan pencegahan TACO dapat dilakukan dengan strategi transfusi yang restriktif, aturan penggunaan transfusi sel darah merah dosis tunggal, identifikasi pasien berisiko tinggi dengan menggunakan algoritma atau ceklist, monitoring intensif pada pasien berisiko, pemberian infus produk darah dengan kecepatan lambat, dan penggunaan obat-obatan diuretik preemtif pada pasien berisiko. Simpulan: Kunci utama penatalaksanaan TACO adalah mencegah terbentuknya edema paru lebih lanjut dengan menghentikan pemberian transfusi dan pemberian oksigen serta diuretik. Sedangkan tindakan pencegahan dapat dilakukan dengan restriksi pemberian produk darah, identifikasi pasien berisiko tinggi hingga pemberian diuretik preemtif.
Dissertations / Theses on the topic "Blood transfusion"
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Kropf, Aline Delduque. "Impacto da implantação de uma equipe transfusional nas atividades de hemovigilância e na segurança transfusional do Hemonúcleo Costa Verde em Angra dos Reis, RJ." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/17/17155/tde-08012019-142634/.
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A transfusão de sangue é um procedimento benéfico, mas não isento de risco, e por essa razão medidas devem ser tomadas para aumentar a sua segurança, entre elas a adoção de boas práticas transfusionais e as notificações dos eventos adversos, que compõe as atividades de hemovigilância. O objetivo do estudo foi avaliar o impacto da implantação de uma equipe transfusional e da busca ativa por reações transfusionais nas atividades de hemovigilância e na segurança transfusional em um Núcleo de Hemoterapia regional, localizado em um hospital geral. Foi realizado um estudo comparativo entre dois períodos: antes e após a implantação da equipe transfusional. Observou-se um aumento de 9,04 vezes no número de notificações de reações transfusionais, elevando de duas notificações em 1.677 transfusões realizadas (0,12%) no período de 22 meses antes da implantação, para dez notificações em 928 transfusões (1,08%, p<0,01) no período de 12 meses após, revertendo a subnotificação existente. As RFNH foram as reações transfusionais mais frequentemente encontradas, havendo aumento significativo nas notificações, de uma RFNH antes para seis após a implantação da equipe transfusional (p<0,01). Observou-se também um aumento na segurança transfusional, corrigindo falhas na identificação de amostras e requisições de transfusão, na verificação dos sinais vitais e identificação dos pacientes, minimizando assim o risco de reações graves por troca de amostras/pacientes. O estudo mostrou que ter um profissional acompanhando o ato transfusional desde a coleta da amostra até o término da transfusão, traz mais segurança para o receptor da transfusão, ao permitir que os procedimentos estabelecidos sejam seguidos, e aumenta as notificações de eventos adversos, favorecendo o reconhecimento das reações transfusionais e fornecendo subsídios para a adoção de estratégias para sua prevenção e tratamento. Ao final do estudo foram elaborados cartazes e panfletos para orientação de profissionais e pacientes, respectivamente, sobre a transfusão de sangue.<br>Blood transfusion can be unavoidable and beneficial but has inherent risks. Hemovigilance actions, therefore, should be undertaken to increase its safety, including the adoption of better blood transfusion initiatives and adverse event reporting. The purpose of this study was to evaluate how the introduction of a transfusion practitioner team to monitor transfusion outcomes affects the hemovigilance system and the transfusion safety in a regional hemotherapy center based in a general hospital. We performed a comparison of two clinical periods: before and after the introduction of a transfusion practitioner team. An increase was observed from 2 event reports in 1677 transfusions (0.12%) in a 22-month period to 10 event reports in 928 transfusions (1.08%, p<0.01) in a 12-month period, demonstrating a 9.04-fold increase in transfusion reaction reports, drastically reducing the frequency of underreporting. Febrile non-hemolytic reactions were the most frequent adverse event reported, with a significant increase from 1 to 6 events reported (p <0.01) after the involvement of the transfusion team. There was also an improvement in transfusion safety practices via the correction of misidentification of patient pretransfusion samples and transfusion requests, the avoidance of failure to verify vital signs, and improvement of patient identification at the bedside, all of which are critical to minimize the risk of transfusion error. The study showed that having a professional team oversee the transfusion process, from sample collection to blood administration, brings more safety to the patient by allowing established procedures to be followed. The adoption of this practice increases reporting of adverse events through the early recognition of transfusion reactions, expediting their treatment and enhancing the prevention of future events. At the end of the study posters and educational packets were created to provide guidance about blood transfusion to leading professionals and patients.
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Pons, Maria J., Pedro Lovato, Jaquelyne Silva, Numan Urteaga, Valle Mendoza Juana Del, and Joaquim Ruiz. "Carrion's disease after blood transfusion." SIMT, 2015. http://hdl.handle.net/10757/604479.
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Bartonella bacilliformis is a pathogen that is endemic
in some areas of the Andean region of Peru, southern
Ecuador and southern Colombia. This pathogen causes
so-called Carrion's disease, a biphasic disease with acute
and chronic phases (called Oroya fever and "Peruvian
wart" respectively1-3). In the absence or delay of
antibiotic treatment, the mortality rate in the acute phase
is up to 88%1. The acute phase is characterised by fever
and severe anaemia and may be followed, several weeks
or months later, by the chronic eruptive phase due to
endothelial cell proliferation2. No animal reservoir has
been identified to date and it is considered that healthy
carriers act as a pathogen reservoir in endemic areas
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Sosnoski, Monalisa. "Lesão de estoque de concentrado de hemácias e a relação com as reações transfusionais febris não hemolíticas." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/172524.
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Introdução: As transfusões de sangue e as Reações transfusionais (RT) têm tido grande destaque nas discussões e estudos da hemoterapia atual, devido a necessidade e relevância para a prática transfusional e na busca em qualificar as transfusões e refinar a classificação das RT. As reações transfusionais febris não hemolíticas (RTFNH) apresentam um crescente no número de notificações e despertam a necessidade de mais estudos. Durante a estocagem dos hemocomponentes, ocorrem uma série de alterações morfológicas, aumento de potássio (K+) extracelular, hemólise e aumento de hemoglobina (Hb) sobrenadante. Analisar a qualidade e viabilidade do hemocomponente pode nos levar a verificar os fatores preditores de uma RT, procurando minimizar os riscos e selecionar um hemocomponente de melhor qualidade ao paciente. Objetivos: Avaliar potenciais fatores etiológicos na precipitação das RTFNH por meio da mensuração na concentração de sódio (Na+) e K+ no sobrenadante, a contagem leucocitária por mcL, o cultural e o Hematócrito (Ht) e Hb da bolsa de concentrado de hemácias (CH) envolvidas, comparando estes parâmetros em relação a um grupo controle de bolsas de CH. Analisar e comparar o perfil dos pacientes envolvidos com a RTFNH e do grupo controle e, estimar a frequência de culturais coletados positivos e os germes envolvidos. Metodologia: Estudo de caso-controle com seleção de amostras a partir de notificações de suspeita de RTFNH ao Serviço de Hemoterapia de um Hospital Universitário de Porto Alegre - RS, no período de setembro de 2015 a setembro de 2016. O grupo controle foi selecionado a partir da mesma população de bolsas, sendo pareadas por tipagem sanguínea e data de vencimento do hemocomponente, numa proporção de 1:2,1. Resultados: o total incluído foi de 124 bolsas, sendo 39(30,5%) do grupo RT e 85(69,5%) do grupo controle, onde uma série de variáveis foram avaliadas. A média de dias de estocagem das bolsas foi de 10,7(DP=6,7) dias, sendo que no grupo RT 12,1(DP=8,1), foi significativamente maior que no grupo controle 10(DP=5,8) com (P=0,037). Também quando avaliamos as dosagens de Ht as médias verificadas foram de 68,3(DP=7,27), sendo no grupo RT 71(DP=81) e 67(DP=6,5) no grupo controle e, na comparação dos grupos, observamos um P<0,001. Dessa forma, a cada dia a mais de estocagem e, a cada ponto a mais no HT da bolsa, há um aumento na chance de aparecimento de RTFNH. Conclusões: a lesão de estocagem é uma temática importante no momento da oferta de hemocomponentes ao paciente, principalmente aos pacientes em tratamento oncológico de tumores sólidos. A avaliação do HT e do tempo de estocagem da bolsa demonstraram ter relevância estatística e clínica na predição de aparecimento de RTFNH. O manejo de estoque adequado para poder haver essa oferta se faz necessário. Novos estudos serão necessários para verificarmos os mecanismos desencadeantes da RTFNH comparado com o Ht da bolsa e, também estudos relacionados à utilização de pré medicação nas transfusões.<br>Introduction: Blood transfusions and the transfusion reactions (TR) have had great emphasis in current hemotherapy discussions and studies, due to its importance in transfusion practice and with the aim of qualifying the transfusions and refining TR classifications. The non-hemolytic febrile transfusion reaction (NHFTR) show an increasing number of notifications and arouse the necessity for further studies. During the storage of blood products a series of morphologic alterations occur, such as extracellular potassium (K+) increase, hemolysis and supernatant Hemoglobin (Hb) increase. Analyzing the blood product quality and availability may lead us to verifying predictive factors of a TR, seeking to minimize the risks and select a blood product of a superior quality for the patient. Objective: Evaluate potential etiological factors in the NHFTR precipitation through sodium (Na+) concentration measurement and K+ in the supernatant, the leukocyte count by mcL, the cultural and the Hematocrit (Ht),and Hb of erythrocyte concentrate bag (EC) involved, comparing those parameters in relation to a control group of EC blood bags. Analyze and compare the profile of the patients involved with a NHFTR to the control group and estimate the frequency of positive cultures collected and the germs involved. Methodology: Case-control study with sampling selections from a notification of NHFTR suspicion at a Hemotherapy Service in a College Hospital in Porto Alegre, RS, during the period from September 2015 to September 2016, where the control-group was selected from the same blood bag population, being grouped by blood type and blood product expiry date, in proportion 1:2.1. Results: Were studied 124 blood bags, being 39(39,5%) from the TR group and 85(69,5%) from the control group, where a series of invariables were evaluated. The mean of blood bag storage was 8.5 days, 10,7(PD=6,7) in the TR group and 10(DP=5,8) in the control group, and when compared they showed a P=0.037. Moreover, when we analyzed the Ht dosage, it was verified an mean of 68,3(DP=7,27), in the TR group and 71(DP=81), 67(DP=6,5) in the control group and, comparing both groups, we observed a P=<0.001. Therefore, with each additional storage day and, with each additional point in the Ht bool bag, the chance of NHFTR appearance increases. Conclusions: Storage injury is an important topic at the moment of the offer of blood components to the patient, especially to the ones with ongoing oncological treatments for solid tumors. The HT evaluation and the storage time of the blood bag demonstrate clinical and statistical relevance in the prediction of NHFTR appearance. The management of adequate storage is fundamental for the offer’s availability. Further studies are needed to verify the triggering mechanisms of NHFTR compared to the Ht of the bag, as well as studies associated with the use of premedication in transfusions.
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Bommel, Jasper van. "Hemodilution, blood transfusion, and regional oxygenation." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2001. http://dare.uva.nl/document/59608.
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Grey, Sharran Louise. "Accelerated red cell transfusion for selected patients receiving blood transfusion at home." Thesis, Manchester Metropolitan University, 2018. http://e-space.mmu.ac.uk/620803/.
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Background: The Community Intravenous Therapy (CIVT) service gives patients the benefit of receiving IV therapies (including blood transfusion) in their own home, avoiding hospital admission. It is important to ensure this service can be offered to as many patients as possible. If red cell transfusion could be safely performed over a shorter duration (accelerated transfusion), this could theoretically increase the capacity of the service without additional resource. Red cell transfusions are usually administered over a minimum of 90 minutes to a maximum of four hours per unit. It was proposed that one unit could be given in 60 minutes (up to a maximum of 2 units per transfusion episode) to medically selected patients who do not have heart failure or other risk factors for circulatory overload. Methods: Physiological tolerability and safety of accelerated transfusion was evaluated by clinically assessing patients for symptoms and signs of transfusion-associated circulatory overload (TACO) after standard and accelerated rate transfusions. The impact on service capacity and staff resource was evaluated by auditing home transfusion workload data to determine the number of patients who were eligible for accelerated rate transfusion and the potential impact this had on treatment delivery time. Patient and practitioner experiences of accelerated transfusion were evaluated by conducting thematic analysis on semi-structured interviews to assess the acceptability and desirability of service change. Results: When accelerated red cell transfusion was performed on medically selected patients who had been screened for risk factors for circulatory overload, accelerated transfusion appeared to be safe. None of the patients in the study (n=25) developed transfusion associated circulatory overload across 269 accelerated transfusions performed. The mean arterial pressure appeared to statistically significantly increase up to 24 hours after blood transfusion regardless of whether it was infused at a standard or accelerated rate, with the group mean remaining within the normal range (standard rate transfusion: p = 0.0441; accelerated rate average across three transfusions: p = 0.009). There was no statistically significant difference between pre and post-transfusion mean arterial pressure measurements when standard and accelerated rate transfusions were compared (average across three accelerated rate transfusions: p = 0.473), showing that accelerated transfusion itself did not cause an increase in mean arterial pressure above that of standard rate transfusion. A significant proportion of haematology patients (57%, 26/46) were medically eligible for accelerated transfusion, and 49% of total transfusion episodes (224/459) were performed as such. Performing accelerated transfusion on eligible patients could potentially save 105 nursing hours, allowing an additional 35 three hour visits or 26 four hour visits per year. Accelerated transfusion was well received by patients. Positive themes from the data included less time receiving healthcare allowing freedom and time to do other things, improvements in comfort and altruism from knowledge that other patients and the service was benefitting. CIVT practitioners were highly motivated and positive about accelerated transfusion. Themes included satisfaction in seeing positive benefits in quality of life and social aspects of patient's lives; improved continuity of care, better work scheduling; increased service capacity, job satisfaction; better working conditions and professional autonomy in clinical decision-making. Conclusion: Accelerated red cell transfusion appears to be safe in medically selected patients. It can potentially increase service capacity through efficient use of staff resource whilst maintaining a safe and high quality service. Understanding of patient and practitioner experience suggested that changing the service to offer accelerated transfusion would be both acceptable and desirable.
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Perelman, Iris. "The Epidemiology of Multiple Blood Component Transfusion." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/38867.
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Multicomponent transfusion, or the transfusion of two or more different blood products, has been poorly studied to date, as most of the existing literature has focused on the use of individual blood products. This is of concern as multicomponent transfusion recipients likely differ with respect to characteristics and health outcomes from patients transfused with only one type of blood component (e.g. greater illness severity). Consequently, available data on individual blood product use and outcomes may not be applicable to multicomponent transfused patients. This thesis project identified and synthesized existing literature on the epidemiology of multicomponent transfusion in hospital inpatients, as well as the characteristics and outcomes of its recipients. Based on 37 observational studies, we found that the prevalence of multicomponent transfusion varied greatly by patient population, transfusion timeframe, and type of multicomponent transfusion being studied. The most common types of multicomponent transfusion across the 37 studies were co-transfusions of red blood cells (RBCs) and platelets, and co-transfusions of RBCs and plasma. Multicomponent transfusion was found to be associated with several negative health outcomes, however this was based on low quality evidence due to lack of control for confounding by indication. Our systematic review on multicomponent transfusion identified several knowledge gaps, including the need for studies focusing on patients with hematological malignancies, and studies identifying patient characteristics predictive of multicomponent transfusion. To address areas of knowledge deficiency, and to characterize multicomponent transfusion locally at our own center, we designed and conducted a retrospective cohort study of adult, transfused hospital inpatients. Based on 55,719 transfused inpatient admissions at the Ottawa Hospital between 2007 and 2017, we calculated the overall prevalence of multicomponent transfusion to be 25.1% (95% CI: 24.7%, 25.5%). Similar to the findings of our systematic review, the prevalence varied greatly by patient type, transfusion timeframe, and type of multicomponent transfusion. In particular, in hematology patients, the prevalence of multicomponent transfusion was 51%. Other patient groups frequently receiving multicomponent transfusions at our institution were cardiac surgery, critical care, cardiology, vascular surgery, trauma, surgery, and internal medicine patients. Using multivariable regression analysis, we found that patient sex, age, and type were predictive of multicomponent transfusion requirement. Additionally, controlling for illness severity and burden, multicomponent transfusion was associated with increased odds of in-hospital mortality, institutional discharge compared to discharge home, and greater length of hospital stay compared to patients transfused with only RBCs. Given our findings that multicomponent transfusion recipients make up a large proportion of transfused hospital patients, and that they have poorer outcomes, it is of importance to continue characterizing these patients – and not only focus on patients receiving a single type of blood component – and to evaluate and monitor the appropriateness of multicomponent transfusion. Additionally, as transfusion practice and guidelines are known to vary from region to region, it is important to study multicomponent transfusion locally, as generalizing results from other studies and centers may not be appropriate. Obtaining robust information on multicomponent transfusion – including prevalence, predictors, and potential health consequences – can aid clinicians in their decision-making for patient blood management, potentially minimizing unnecessary patient exposure to blood products, and maximizing the use of transfusion alternatives and blood conservation methods.
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Stevens, Kim D. "Reducing Errors with Blood Administration Transfusion Systems." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7340.
Full textAbstract:
The intention of implementing technology into healthcare practices is to reduce opportunity for errors in the delivery of providing health care. However, errors still occur, and many times are preventable. Configurations of health information technology systems should match clinical workflows to promote usage as intended. The purpose of this quality improvement project was to evaluate the impact of revised system configurations and use of a blood product transfusion system for the administration of blood products after one year of implementation. The method of heuristic evaluation is a usability engineering method for finding problems in a user interface design with the input of a small workgroup of subject matter experts. The project site had experienced reported incidents of blood product administration error as well as problems with systems communication since the implementation of the blood transfusion system. There were 31 nurse clinical educator staff users of the system who completed a survey evaluation of their perceptions of the blood transfusion system before and after configuration changes. The findings revealed that the mean quality and productivity score after the system configuration occurred was significantly higher than the mean score prior to the system configuration change, t (30) = -7.93, p < .001. The correlation between the one survey was also statistically significant, r = .46, p = .009. This project supports positive social change by reducing the potential for error for system users in the process of the blood administration process through heuristic evaluation through the implementation of changes to the technological system.
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Valério, Vivianne Teixeira Duarte. "Estudo das Reações Transfusionais Agudas em um Hospital Escola de Goiânia-GO." Pontifícia Universidade Católica de Goiás, 2015. http://localhost:8080/tede/handle/tede/3002.
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Previous issue date: 2015-03-11<br>Blood transfusion is a well-established and an essential therapy in clinical settings. In
practical terms, blood transfusion presents risks to the receptor even when it is
properly administered and when it follows transfusion rules; This adverse events may
occur, they so-called transfusion reaction. The present study evaluate acute
transfusion reaction in the Clinical Hospital of Goiás between January to June 2014.
This is a prospective epidemiological study based on a quantitative approach. We
performed data collection through two different ways. Firstly by an active search for
evidence of acute transfusion reaction in transfusion and medical records and
secondly by spontaneous reporting. Data collection started after the Research Ethics
Committee approval report number 490,699. After the data collection, they were
recorded and analyzed using the statistical software Bioestat 5.0. We adopted a
significance level of 5% (p ≤ 0.05) or all the analyzes. The rate of acute transfusion
reactions analyzed by active search was 10.6 in 852 transfusions and 1.8 of
spontaneous reports in 5440 transfusions, covering an underreporting rate of 47.4%.
The packed red blood cells prevailed as the most common blood component in
transfusion related to reactions (61.3%). Age and gender distribution were not
statistically significant (p = 0.0912 and 0.9982 respectively). Allergic reaction was the
most common event (n = 13, 68.4%). Interestingly the rate of febrile non-hemolytic
transfusion reaction was small (n=2, 10.5%), the volume overload represented (n=2,
10.5%) of the reactions and the hypotensive response rate was (n = 1, 5.3%). The
results show an improvement of the reports in the Clinical Hospital of Goiás
compared to the reports described in the national Haemovigilance in 2014. It is less
than ideal and it reflects the situation of the hemotherapy in country, with few reports
and a small production of national knowledge on the subject.<br>A transfusão de sangue é uma terapêutica consagrada e essencial em situações
clínicas. Na prática, apesar de corretamente administrada e obedecendo às normas
vigentes, a transfusão apresenta riscos ao receptor, podendo ocorrer eventos
adversos chamados de reações transfusionais. Este trabalho teve como objetivo
avaliar as reações transfusionais agudas ocorridas no Hospital das Clínicas de
Goiás, no período de janeiro a junho de 2014. Trata-se de um estudo epidemiológico
prospectivo com abordagem quantitativa. A coleta de dados foi guiada por dois
caminhos, a busca ativa por evidências de reações transfusionais agudas nos
registros transfusionais e prontuários, e pelas notificações espontâneas. A coleta de
dados iniciou-se após aprovação pelo Comitê de Ética em Pesquisa da PUC-GO sob
parecer nº. 490.699. Após a coleta dos dados, os mesmos foram registrados e
analisados no pacote estatístico Bioestat, 5.0. Em todas as análises adotou-se um
nível de significância de 5% (p ≤ 0,05). A incidência de reações transfusionais
agudas encontrada nas transfusões estudadas por busca ativa foi de 10,6 em 852
hemocomponentes transfundidos, já a notificada espontaneamente foi 1,8 em
5440 transfusões, perfazendo uma taxa de subnotificação de 47,4%. O concentrado
de hemácias prevaleceu como o hemocomponente mais associado às reações
transfusionais (61,3%), a distribuição por gênero não foi estatisticamente significativa
(p=0,9982) e nem por idade (p= 0,0912). A reação alérgica foi a reação mais comum
(n=13, 68,4%), fato interessante é a pequena ocorrência de reação febril não
hemolítica (n=2, 10,5%), a sobrecarga volêmica representou (n=2, 10,5%) das
reações encontrados, reação hipotensiva (n=1, 5,3%). Os resultados encontrados
demonstram um avanço das notificações no Hospital das Cínicas de Goiás em
relação às notificações do estado de Goiás descritas no relatório de hemovigilância
nacional 2014, mas aquém do ideal e reflete a situação da hemoterapia do país, com
poucas notificações e pequena produção de conhecimento nacional acerca do
assunto.
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Morris, Rebecca Hazel. "Bloody geographies : relating, connecting, giving and caring in blood donation and transfusion." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/552/.
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This thesis critically questions, through in-depth qualitative research, the senses of connection, giving, care, and relatedness felt by blood donors and recipients, given the institutional setting of therapeutic blood exchange in the UK. In it, I use a multi-sited auto-ethnographic approach to examine five blood donor-/recipient-participant views on blood donation and transfusion. Specifically, I blend theoretical and empirical research to iterate between the meanings and realities associated with therapeutic blood exchange, exploring and examining the following things. First, I explore how blood can be treated as material culture: what it is as both biological tissue and as social/cultural metaphor. Second, I examine how gift giving and caring feed into and out of blood exchange, and whether this fosters a sense of connectedness for the anonymous others at the end of the blood pack. Third, I roll out the theme of connectedness to look at (the geographies of) relatedness where I examine the changing nature of kinship and its evolution into the concept of relatedness. Here, I examine how both relating through ‘things’ and at different scales could perhaps more usefully describe the connection/relationship between donors and recipients...or not. Finally, I draw this together, examining how the institutional framework of the National Blood Service can be said to either foster or not, the senses of connectedness and/or relatedness, gift giving and care between its donors and recipients.
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Blasi, Brugué Carles. "Advances in feline transfusion medicine." Doctoral thesis, Universitat Autònoma de Barcelona, 2021. http://hdl.handle.net/10803/673650.
Full textAbstract:
La medicina transfusional consisteix en una teràpia de reemplaçament de components sanguinis per a pacients en situació de dèficit, sent en molts casos un procediment necessari per a mantenir al pacient viu. Tot i així, no està exempt de riscos, els quals estan molt influenciats pels mètodes de producció, emmagatzematge i administració.
La medicina transfusional felina es considera especialment associada a dificultats tècniques i, per tant, històricament s’ha vist restringida a l’ús de sang sencera. No obstant això, en les últimes dècades hi ha hagut grans avenços en els bancs de sang felina, els quals han començat a produir i oferir components sanguinis felins fabricats extrapolant mètodes de producció i emmagatzematge de la medicina humana i canina. L’evidència científica que dóna suport a la seguretat i eficàcia d’aquests mètodes en els bancs de sang felina és escassa. A causa de la mida més petita dels donants i receptors de sang, així com les diferències fisiològiques entre espècies i les diferències hemorreològiques dels eritròcits felins en comparació amb els glòbuls vermells canins i humans, extrapolar la informació entre espècies pot suposar un gran risc pel que fa a la seguretat i eficàcia de les transfusions felines.
L’objectiu d’aquesta tesi doctoral és establir les bases per a la producció, conservació i administració dels components sanguinis felins més comuns: concentrat d’eritròcits (CE) felí i plasma fresc congelat (PFC) felí. Tenint en compte això, el projecte es divideix en tres apartats, dos d’ells sobre CE felí i un centrat en PFC felí. El primer va ser dissenyat amb l’objectiu d’estudiar el dany per emmagatzematge dels CE felins i verificar la viabilitat dels sistemes de recol·lecció semitancats per a les donacions de sang felina. El segon estudi té com a objectiu determinar si l’ús de bombes d’infusió peristàltiques en la transfusió de CE felins indueix en el grau d’hemòlisi i, per tant, si és segur utilitzar-les. I l’últim té com com a objectiu estudiar la concentració i estabilitat dels factors de coagulació durant l’emmagatzematge de l’PFC felí.<br>La medicina transfusional consiste en una terapia de reemplazo de componentes sanguíneos para pacientes en situación de déficit, siendo en muchos casos un procedimiento necesario para la vida. Aun así, no está exento de riesgos, los cuales están muy influenciados por los métodos de producción, almacenamiento y administración.
La medicina transfusional felina se considera especialmente asociada a dificultades técnicas y, por tanto, históricamente se ha visto restringida al uso de sangre entera. Sin embargo, en las últimas décadas ha habido grandes avances en los bancos de sangre felina, los cuales han empezado a producir y ofrecer componentes sanguíneos felinos fabricados extrapolando métodos de producción y almacenamiento de la medicina humana y canina. La evidencia científica que respalda la seguridad y eficacia de estos métodos en los bancos de sangre felina es escasa. Debido al menor tamaño de los donantes y receptores de sangre, así como las diferencias fisiológicas entre especies y las diferencias hemorreológicas de los eritrocitos felinos en comparación con los glóbulos rojos caninos y humanos, extrapolar la información entre especies puede suponer un gran riesgo en cuanto a seguridad y eficacia de las transfusiones felinas.
El objetivo de esta tesis doctoral es sentar las bases para la producción, conservación y administración de los hemoderivados felinos más comunes: concentrado de eritrocitos (CE) felino y plasma fresco congelado (PFC) felino. Teniendo esto en cuenta, el proyecto se divide en tres apartados, dos de ellos sobre CE felino y uno centrado en PFC felino. El primero fue diseñado con el objetivo de estudiar el daño por almacenamiento de los CE felinos y verificar la viabilidad de los sistemas de recolección semicerrados para las donaciones de sangre felina. El segundo estudio tiene como objetivo determinar si el uso de bombas de infusión peristálticas en la transfusión de CE felinos induce hemólisis y, por tanto, si es seguro utilizarlas. Y el último tuvo como objetivo estudiar la concentración y estabilidad de los factores de coagulación durante el almacenamiento del PFC felino.<br>Transfusion medicine consists in a blood component replacement therapy for patients in a situation of deficiency, being in many cases a lifesaving procedure. Even so, it is not exempt of risks, which are highly influenced by the methods of production, storage and administration.
It is considered that feline transfusion medicine is especially associated with technical difficulties and thus, it has historically been restricted to the use of whole blood. Nevertheless, in the recent decades there have been great advances in feline blood banking, and blood banks have begun to produce and offer feline blood components manufactured by extrapolating methods of production and storage from human and canine medicine. The scientific evidence to support the safety and efficacy of these methods in feline blood banking is scant. Due to the smaller size of blood donors and recipients, as well as the physiological differences between species and the hemorheological differences of feline erythrocytes compared to canine and human red blood cells, extrapolating the information between species can pose a great risk regarding the safety and efficacy of feline transfusions.
The objective of this doctoral thesis is to establish the bases for the production, conservation, and administration of the most common feline blood products: feline pRBC and feline FFP. With this in mind, the project is divided into three sections, two of them about feline pRBC and one centred in feline FFP. The first was designed with the objective of studying storage damage over feline pRBC, and to verify the viability of semi-closed collection systems for feline blood donations. The second study aims to determine if the use of peristaltic infusion pumps in feline pRBC transfusion induces haemolysis and thus, if it is safe to use them. And the last one aimed to study coagulation factor concentration and stability during storage in feline fresh frozen plasma.<br>Universitat Autònoma de Barcelona. Programa de Doctorat en Medicina i Sanitat Animals
Books on the topic "Blood transfusion"
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Callum, J. L. Bloody easy: Blood transfusions, blood alternatives and transfusion reactions : a guide to transfusion medicine. Sunnybrook and Women's College Health Sciences Centre, 2003.
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Callum, J. L. Bloody easy 2: Blood transfusions, blood alternatives and transfusion reactions : a guide to transfusion medicine. 2nd ed. Sunnybrook and Women's College Health Sciences Centre, 2005.
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F, Galley Helen, and Intensive Care Society (Great Britain), eds. Blood and blood transfusion. BMJ Books, 2002.
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1926-, Bove Joseph R., and Case, John, F.I.M.L.S., eds. Practical blood transfusion. 4th ed. Little, Brown, 1988.
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C, Jefferies Leigh, and Brecher Mark E, eds. Massive transfusion. American Association of Blood Banks, 1994.
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H, Smit Sibinga Th. Blood transfusion and blood components. World Health Organization, Regional Office for the Eastern Mediterranean, 1995.
Find full textBook chapters on the topic "Blood transfusion"
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Soni, Kapil Dev, and Rahul Chaurasia. "How to Use Blood and Blood Products." In Rational Use of Intravenous Fluids in Critically Ill Patients. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-42205-8_12.
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AbstractThis chapter discusses the available evidence for blood transfusions in various subgroups of critically ill patients and other common issues pertaining to the transfusion of blood and blood components in the ICU. While blood and blood products can a be lifesaving therapy, the decision to transfuse should be based on individual factors, and the risk–benefit ratio of adverse events should be considered. Restrictive red blood cell (RBC) transfusion strategies are generally more beneficial, and platelet transfusions should be administered after risk assessment for bleeding, cause and pattern of thrombocytopenia, and presence of underlying comorbidities. Point-of-care tests such as thromboelastography (TEG) or rotational thromboelastometry (ROTEM) can help guide blood transfusions. Common transfusion reactions in the ICU include transfusion-related acute lung injury (TRALI), transfusion-associated circulatory overload (TACO), and nosocomial infections. Transfusion alternatives such as IV iron, erythropoietin, and tranexamic acid should be considered whenever feasible.
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Chaubey, Vikas P., Kevin B. Laupland, Christopher B. Colwell, et al. "Blood Transfusion." In Encyclopedia of Intensive Care Medicine. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-00418-6_343.
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Coventry, Brendon J. "Blood Transfusion." In Cardio-Thoracic, Vascular, Renal and Transplant Surgery. Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-5418-1_2.
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Sanders, David W., and Jeffrey L. Carson. "Blood Transfusion." In Evidence-Based Orthopedics. Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9781444345100.ch9.
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Jones, Meredyth L. "Blood Transfusion." In Veterinary Techniques for Llamas and Alpacas. Wiley-Blackwell, 2013. http://dx.doi.org/10.1002/9781118695111.ch73.
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MacDermott, Siobhan, and Karen Merrick. "Blood transfusion." In Foundation Skills for Caring. Macmillan Education UK, 2009. http://dx.doi.org/10.1007/978-1-137-11733-5_34.
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Kam, Peter, Ian Power, Michael J. Cousins, and Philip J. Siddal. "Blood Transfusion." In Principles of Physiology for the Anaesthetist. CRC Press, 2020. http://dx.doi.org/10.1201/9780429288210-54.
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Green, Jan. "Blood transfusion." In Haematology Nursing. John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118702949.ch17.
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Chorba, Terence L., and Bruce L. Evatt. "Transfusion-associated AIDS." In Blood, Blood Products — and AIDS —. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4899-3394-2_2.
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Van Heurn, Ernest. "Blood/Blood Products Transfusion." In Pediatric Surgery Digest. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-34033-1_4.
Full textConference papers on the topic "Blood transfusion"
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saeidi, Reza, Azra Izanloo, and Syed Ali Reza Tabatabaei. "P347 Blood transfusion in NICU." In Faculty of Paediatrics of the Royal College of Physicians of Ireland, 9th Europaediatrics Congress, 13–15 June, Dublin, Ireland 2019. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2019. http://dx.doi.org/10.1136/archdischild-2019-epa.694.
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Darwiche, Mohamad, Mathieu Feuilloy, Ghazi Bousaleh, and Daniel Schang. "Prediction of blood transfusion donation." In 2010 Fourth International Conference on Research Challenges in Information Science (RCIS). IEEE, 2010. http://dx.doi.org/10.1109/rcis.2010.5507363.
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Kocjančič, Boštjan, and Ema Kocjančič. "The Use of Tranexamic Acid in Orthopaedic Surgery." In Socratic Lectures 8. University of Lubljana Press, 2023. http://dx.doi.org/10.55295/psl.2023.i9.
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New surgical techniques (minimally invasive surgery – (MIS), laparoscopic surgery), meticulous consideration of haemostasis, use of robots, Cell Saver and tranexamic acid, new transfusion criteria and single red blood cell (RBC) unit ordering have greatly changed clinical practices. Implementation of these therapeutic options along with other practices has significantly contributed to the effectiveness of the patient blood management approach to surgical patients. In recent years use of anti-fibrinolytic agent tranexamic acid (TXA) has been introduced at our department and intravenous administration as well as topical TXA administration were successfully implemented. Use of topical TXA was effective at reducing both post-operative red blood cell loss and transfusion rates with good tolerance and no clinically relevant adverse events. Within 6 years of Patient Blood Management (PBM) protocol implementation in our institution, the total number of transfusions was reduced by 76 % and the percentage of patients requiring transfusion fell from 38 % to 9 %. Keywords: Tranexamic acid; Blood loss; Orthopaedic surgery; Endoprosthesis; Joint arthroplasty
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Murphree, Dennis H., Leanne Clifford, Yaxiong Lin, et al. "Predicting Adverse Reactions to Blood Transfusion." In 2015 International Conference on Healthcare Informatics (ICHI). IEEE, 2015. http://dx.doi.org/10.1109/ichi.2015.17.
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Charrière, Karine, Jean-Francois Manceau, Pascal Morel, et al. "Test Device for Blood Transfusion Safety." In 11th International Conference on Biomedical Electronics and Devices. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0006635702060211.
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Ben-Hur, Ehud. "Photodynamic decontamination of blood for transfusion." In Photodynamic Therapy of Cancer II. SPIE, 1995. http://dx.doi.org/10.1117/12.199140.
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WILL, R. G. "CREUTZFELDT-JAKOB DISEASE AND BLOOD TRANSFUSION." In The 32nd Session of International Seminars and International Collaboration. WORLD SCIENTIFIC, 2005. http://dx.doi.org/10.1142/9789812701787_0013.
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Nichols, W. L., T. M. Habermann, S. E. Kaese, and E. J. W. Bowie. "GLANZMANN'S THROMBASTHENIA: HEMOSTATIC EFFECTIVENESS OF PLASMA CRYOPRECIPITATE TRANSFUSION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644744.
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A 39-year-old 75 kg man with Type I Glanzmann's thrombasthenia developed recurring severe therapy-refractory nosebleeds, associated with nasal septal deformity, synechial scarring, and previous radiotherapy. During a 21 month period he required 16 hospitalizations for treatment of severe epistaxis. At initial hospitalization it was observed that his epistaxis ceased shortly after transfusion of 10 bags (units) of plasma cryoprecipitate (cryo), although transfusion with HLA-matched apheresis platelets from 3 donors, and topical therapy (cautery, packing), had been ineffective. Serum anti-platelet antibodies were not detectable by indirect immunofluorescence. During 9 subsequent hospitalizations his epistaxis stopped promptly (usually within 1 hour) following cryo transfusion (10 or 20 bags), including 6 occasions when cryo was the only therapy. On 6 additional occasions his epistaxis did not stop following cryo transfusion, but did stop after subsequent platelet transfusions or topical therapy. Eventually he underwent nasal septal reconstructive surgery surgery, and severe epistaxis has not recurred. Hemostatic studies, before and after cryo transfusions on 5 occasions, did not show improvement of platelet aggregation defects nor of Ivy bleeding times, although occasionally the volume of blood emanating from bleeding time punctures appeared decreased following cryo transfusion. Platelet glycoprotein (GP) IIb/IIIa antigen was measured in aliquots of 10 of the pools of cryo received by the patient (representing 100 bags of total volume 2200 ml), using an immunoradiometric assay (Nichols et al, Blood 68:300a, 1986). On average, the transfused cryo pools contained GP IIb/IIIa equivalent to 1.1 x 108 platelets/ml (range 0.6-1.7 x 108/ml. Our recently reported studies of blood bank cryo documented similar GP IIb/IIIa levels, and revealed that >93% of GP IIb/IIIa in cryo is present in the form of sedimentable membranous platelet macroparticles and microparticles. We hypothesize that the GPIIb/IIla-bearing platelet particles in transfused cryo might account for the improvement in hemostasis we frequently observed. We conclude that cryo transfusion deserves further study as a potentially useful therapeutic adjunct in promoting hemostasis in individuals with Glanzmann's thrombasthenia.
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Evdochim, Lucian, Aleksei E. Zhdanov, Vasilii I. Borisov, Dragos Dobrescu, and Leonid G. Dorosinsky. "Blood Mixers for Transfusion Therapy:Photoplethysmogram application for blood velocity determination." In 2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA). IEEE, 2020. http://dx.doi.org/10.1109/memea49120.2020.9137214.
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"Clinical Disease Registry Ontology for Blood Transfusion." In Universal Researchers. Universal Researchers, 2014. http://dx.doi.org/10.17758/ur.u1214018.
Full textReports on the topic "Blood transfusion"
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Fildes, John, Timothy D. Browder, Uwe Rockenfeller, Kaveh Khalili, and Ryan Hoffmann. High Speed Blood and Transfusion Equipment. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada622211.
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Fildes, John, Tim Browder, Michael Russo, et al. High Speed Blood and Fluid Transfusion Equipment. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada521781.
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Wee, Prof M. Y. K., Dr D. Thomas, Dr R. Verma, et al. Blood transfusion and the anaesthetist: Intra-operative cell salvage. The Association of Anaesthetists of Great Britain and Ireland, 2009. http://dx.doi.org/10.21466/g.btata-i.2009.
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Cotton, Bryan A., Charles E. Wade, and Rosemary A. Kozar. Early Whole Blood for Patients Requiring Massive Transfusion after Major Trauma. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada577325.
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Schreiber, Martin A., Jerome A. Differding, Loic J. Fabricant, et al. Efficacy and Safety of Frozen Blood for Transfusion in Trauma Patients. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada597687.
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Fan, Qisen. The effectiveness of acute normovolemic hemodilution reduces allogeneic blood transfusion during hepatectomy: A meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.4.0011.
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Wu, Ming-Kung, and Ping-Tao Tseng. Efficacy of different interventions to reduce pre- or perioperative blood transfusion rate in patients with colorectal cancer: A network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.4.0143.
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Bucknell, Allan L., Michael B. Simpson, Kevin P. Murphy, and Henry G. Chambers. Evaluation of Effect of Postoperative Wound Drainage Reinfusion Using the Solcotrans Orthopaedic Drainage/Reinfusion System in Reducing the Need for Whole Blood Transfusion (HSC). Defense Technical Information Center, 1991. http://dx.doi.org/10.21236/ada238271.
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Luo, Pan, Fuqiang Gao, Nianfei Zhang, Hongwei Yu, Ke Xu, and Peng Xu. Evaluation of tranexamic acid after total hip arthroplasty over 60 years old in China: a Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.1.0048.
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Review question / Objective: The purpose of this meta-analysis was to evaluate the efficacy of tranexamic acid after total hip arthroplasty in patients older than 60 years old in China by meta-analysis. Participant or population: All trials included in our study meet the following criteria: (1) All studies were original RCTs; (2) The mean age of patients for each study was ≥ 60 years old; (3) Patients were received total hip arthroplasty in all studies; (4) All studies included oral and iv or topical groups, with a comparison of outcomes between the two groups; (5) The full text of the included literature can be obtained, and the measurement data of hemoglobin drop, total blood loss, transfusion rate, complication, length of stay can be extracted. The following studies were excluded from the meta-analysis: nonrandomized studies; the patients with age<60; studies not suitable with the inclusive criteria; and articles for which we were unable to obtain the full text and relevant data for pooled analysis.
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Cornum, Rhonda L. Blood Amplification: Use of Phosphoenolpyruvate (PEP) Treated Red Blood Cell Transfusions in the Dog (Canis familiaris). Defense Technical Information Center, 1996. http://dx.doi.org/10.21236/ada306015.
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