Relevant bibliographies by topics / BMP [Bone morphogenic protein]

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'BMP [Bone morphogenic protein]'

Author: Grafiati
Published: 4 June 2021
Last updated: 4 February 2022

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Journal articles on the topic "BMP [Bone morphogenic protein]"

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Herberg, S., A. M. McDermott, P. N. Dang, et al. "Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair." Science Advances 5, no. 8 (2019): eaax2476. http://dx.doi.org/10.1126/sciadv.aax2476.

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Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell condensation, directed by local morphogen signals and mechanical cues. Here, we aimed to mimic development for regeneration of large bone defects. We hypothesized that engineered human mesenchymal condensations presenting transforming growth factor–β1 (TGF-β1) and/or bone morphogenetic protein-2 (BMP-2) from encapsulated microparticles promotes endochondral defect regeneration contingent on in vivo mechanical cues. Mesenchymal condensations induced bone formation dependent on morph
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Shah, Prasun, Louis Keppler, and James Rutkowski. "Bone Morphogenic Protein: An Elixir for Bone Grafting—A Review." Journal of Oral Implantology 38, no. 6 (2012): 767–78. http://dx.doi.org/10.1563/aaid-joi-d-10-00196.

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Bone morphogenetic proteins (BMPs) are multifunctional growth factors that belong to the transforming growth factor beta superfamily. This literature review focuses on the molecular biology of BMPs, their mechanism of action, and subsequent applications. It also discusses uses of BMPs in the fields of dentistry and orthopedics, research on methods of delivering BMPs, and their role in tissue regeneration. BMP has positive effects on bone grafts, and their calculated and timely use with other growth factors can provide extraordinary results in fractured or nonhealing bones. Use of BMP introduce
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SINGH, GANESH R. "Bone Morphogenic Protein - A short communication." CODS Journal of Dentistry 2, no. 1 (2010): 1–3. http://dx.doi.org/10.5005/cods-2-1-1.

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Okamoto, Tomoyo, Satoru Kodama, Nozomi Nomi, Shingo Umemoto, and Masashi Suzuki. "Expression of Bone Morphogenic Protein in Sinonasal Inverted Papilloma with New Bone Formation." Allergy & Rhinology 2, no. 1 (2011): ar.2011.2.0004. http://dx.doi.org/10.2500/ar.2011.2.0004.

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Inverted papilloma (IP) is a common benign tumor in the nose and sinus. Osteogenesis in sinonasal IP is extremely rare; to date, only five cases of IP with new bone formation appear in the literature. In addition, the mechanism of osteogenesis in IP remains unclear. Here, we describe three cases of IP with new bone formation and an investigation into a possible role for bone morphogenic protein (BMP) in osteogenesis. Of three patients with sinonasal IP with new bone formation, two were treated by endoscopic sinus surgery and one was followed up with watchful waiting. Tumor tissues were subject
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Song, Sang-Heon, Young-Pil Yun, Hak-Jun Kim, Kyeongsoon Park, Sung Eun Kim, and Hae-Ryong Song. "Bone Formation in a Rat Tibial Defect Model Using Carboxymethyl Cellulose/BioC/Bone Morphogenic Protein-2 Hybrid Materials." BioMed Research International 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/230152.

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The objective of this study was to assess whether carboxymethyl cellulose- (CMC-) based hydrogel containing BioC (biphasic calcium phosphate (BCP); tricalcium phosphate (TCP) : hydroxyapatite (Hap) = 70 : 30) and bone morphogenic protein-2 (BMP-2) led to greater bone formation than CMC-based hydrogel containing BioC without BMP-2. In order to demonstrate bone formation at 4 and 8 weeks, plain radiographs, microcomputed tomography (micro-CT) evaluation, and histological studies were performed after implantation of all hybrid materials on an 8 mm defect of the right tibia in rats. The plain radi
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Tsai, Ya-Ting, Chao-Wei Huang, Hui-Yu Liu, et al. "Enhanced bone morphogenic property of parylene-C." Biomaterials Science 4, no. 12 (2016): 1754–60. http://dx.doi.org/10.1039/c6bm00664g.

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Functional biomolecules of bone morphogenetic protein (BMP)-2, fibronectin, and platelet-rich plasma (PRP) are modified on parylene-C surfaces via a protein adsorption process. The resulting surfaces are showing induced osteogenetic activities.
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Rosenberg, Michal, Dekel Shilo, Leonid Galperin, et al. "Bone Morphogenic Protein 2-Loaded Porous Silicon Carriers for Osteoinductive Implants." Pharmaceutics 11, no. 11 (2019): 602. http://dx.doi.org/10.3390/pharmaceutics11110602.

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Bone morphogenetic proteins (BMPs) are probably the most important growth factors in bone formation and healing. However, the utilization of BMPs in clinical applications is mainly limited due to the protein poor solubility at physiological pH, rapid clearance and relatively short biological half-life. Herein, we develop degradable porous silicon (PSi)-based carriers for sustained delivery of BMP-2. Two different loading approaches are examined, physical adsorption and covalent conjugation, and their effect on the protein loading and release rate is thoroughly studied. The entrapment of the pr
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Hartung, Anke, Keren Bitton-Worms, Maya Mouler Rechtman, et al. "Different Routes of Bone Morphogenic Protein (BMP) Receptor Endocytosis Influence BMP Signaling." Molecular and Cellular Biology 26, no. 20 (2006): 7791–805. http://dx.doi.org/10.1128/mcb.00022-06.

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ABSTRACT Endocytosis is important for a variety of functions in eukaryotic cells, including the regulation of signaling cascades via transmembrane receptors. The internalization of bone morphogenetic protein (BMP) receptor type I (BRI) and type II (BRII) and its relation to signaling were largely unexplored. Here, we demonstrate that both receptor types undergo constitutive endocytosis via clathrin-coated pits (CCPs) but that only BRII undergoes also caveola-like internalization. Using several complementary approaches, we could show that (i) BMP-2-mediated Smad1/5 phosphorylation occurs at the
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Kim, So-Yeun, Eun-Bin Bae, Jae-Woong Huh, et al. "Bone Regeneration Using a Three-Dimensional Hexahedron Channeled BCP Block Combined with Bone Morphogenic Protein-2 in Rat Calvarial Defects." Materials 12, no. 15 (2019): 2435. http://dx.doi.org/10.3390/ma12152435.

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It is important to obtain sufficient bone mass before implant placement on alveolar bone, and synthetic bone such as biphasic calcium phosphate (BCP) has been studied to secure this. This study used a BCP block bone with a specific structure of the three-dimensional (3D) hexahedron channel and coating with recombinant human bone morphogenetic protein-2 (rhBMP-2) impregnated carboxymethyl cellulose (CMC) was used to examine the enhancement of bone regeneration of this biomaterial in rat calvarial defect. After the preparation of critical-size calvarial defects in fifteen rats, defects were divi
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Weaver, John, and Jason Eubanks. "Takotsubo Cardiomyopathy following a L2–L5 Laminectomy and Fusion In Situ with Bone Morphogenic Protein." Case Reports in Orthopedics 2013 (2013): 1–4. http://dx.doi.org/10.1155/2013/724960.

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Takotsubo cardiomyopathy (TC) is a rare, transient cardiomyopathy, with symptoms mimicking myocardial infarction. It has been reported to typically occur in postmenopausal women and is often triggered by an intense physical or emotional event with stimulation of the sympathetic response; the exact etiology, however, is uncertain. Bone morphogenic protein (BMP) is widely used in spinal fusions and has been associated with numerous perioperative complications. BMP is known to stimulate sympathetic pathways. In this paper, we present the case of a patient with a 7-hour episode of TC after a spina
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Dissertations / Theses on the topic "BMP [Bone morphogenic protein]"

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Costa, Carla Christina Rodrigues. "BMP (Bone Morphogenetic Protein) : uma abordagem terapêutica inovadora." Universidade de Taubaté, 2008. http://www.bdtd.unitau.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=459.

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A odontologia, atualmente, conta com uma nova abordagem terapêutica no campo da regeneração tecidual. Essa abordagem baseia-se no uso de moléculas bioativas, mais especificamente as BMPs (Bone Morphogenetic Proteins). A presente revisão propõe-se a apresentar alguns relatos, existentes na literatura, do uso das BMPs como medicamento, dando embasamento para realização de novos experimentos que possam sugerir abordagens terapêuticas inovadoras na área da regeneração tecidual. As BMPs são proteínas pleiotrópicas, que estão envolvidas no desenvolvimento de vários órgãos do corpo humano, e, também,
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Liu, Jin. "Increased CKIP-1 suppresses Smad-dependent BMP signaling to inhibit bone formation during aging." HKBU Institutional Repository, 2016. https://repository.hkbu.edu.hk/etd_oa/327.

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Emerging evidence indicates that the dysregulation of protein ubiquitination plays a crucial role in aging-associated diseases. Smad-dependent canonical BMP signaling pathway is indispensable for osteoblastic bone formation, which could be disrupted by the ubiquitination and subsequent proteasomal degradation of Smad1/5, the key molecules for BMP signaling transduction. However, whether the dysregulation of Smad1/5 ubiquitination and disrupted BMP signaling pathway are responsible for the age-related bone formation reduction is still underexplored. Casein kinase-2 interacting protein-1 (CKIP-1
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Ren, Rongqin Patterson Cam. "The essential role of bone morphogenetic protein (BMP) signaling in organogenesis." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1260.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Mar. 26, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Cell and Developmental Biology." Discipline: Cell and Developmental Biology; Department/School: Medicine.
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Rocher, Crystal. "Bone Morphogenetic Protein-7 (BMP-7) Polarizes Monocytes into M2 Macrophages." Master's thesis, University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5849.

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Atherosclerosis is an inflammatory disease in which an accumulation of fatty acids and cholesterol occurs to form a plaque in small and large arteries. Monocyte polarization to classic M1 macrophages or alternative M2 macrophages is an important area of research that can determine the severity of disease progression. BMP-7 is a key growth factor responsible for directing differentiation of mesenchymal stem cells into brown fat cells, suggesting a role of BMP-7 in cellular plasticity; however, its role in monocyte polarization is yet to be revealed. In the current study, we hypothesize that mon
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Zhou, Lixiong, and 周立雄. "Differential action of bone morphogenetic protein BMP-2 and BMP-7 on nucleus pulposus cells of intervertebral disc." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/209509.

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Low back pain (LBP) is associated with intervertebral disc (IVD) degeneration and exerts enormous socioeconomic burdens on the society. The nucleus pulposus (NP) is the structural and functional core of the IVD, and plays vital roles in its homeostasis. Although the etiology of IVD degeneration is not fully understood, the cellular changes of the NP have been proposed to be associated with degeneration. Conventional management for IVD degeneration primarily targets to relieve LBP and other symptoms without restoring or preserving disc function. Novel therapeutic strategies have emerged with an
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Patel, Mamta Jashvantlal. "Suppression of osteoblast activity by disuse is prevented by low magnitude mechanical loading through a bone morphogenic protein-dependent Mechanism." Diss., Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/22663.

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Musculoskeletal pathologies associated with decreased bone mass, including osteoporosis and disuse-induced bone loss, affect millions of Americans annually. Many pharmaceutical treatments have slowed osteoporosis, but there is still no countermeasure for bone loss observed in astronauts. Additionally, high magnitude and low frequency impact has been recognized to increase bone and muscle mass under normal but not microgravity conditions. However, a low magnitude and high frequency (LMHF) mechanical load experienced in activities such as postural control has also been shown to be anabolic to
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Forbes-Robertson, Sarah Anne Natasha. "Structure and expression of the chicken bone morphogenetic protein-2 gene." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244093.

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Patel, Neeta. "The regulation of the hepcidin by modulators of the bone morphogenetic protein (BMP) pathway." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/the-regulation-of-the-hepcidin-by-modulators-of-the-bone-morphogenetic-protein-bmp-pathway(2c0cf0c3-c02d-4bc1-ac9f-910eda793afc).html.

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Hepcidin, the iron regulatory peptide, has emerged as the master regulator of systemic iron homeostasis. Under normal circumstances, hepcidin expression is upregulated by excess iron and inflammation; and downregulated by iron deficiency, anaemia and hypoxia. Insights gained into the pathogenesis of iron-storage disorders such as hereditary haemochromatosis (HH) and hypotransferrinaemia (HPX), have contributed to the identification of the molecular mechanisms governing hepcidin expression. In these disorders, hepcidin expression is inappropriately low, causing increased absorption of iron by t
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Bressan, Michael C. "BMP signaling and tenascin-C in vascular development and remodeling /." Access full-text from WCMC, 2009. http://proquest.umi.com/pqdweb?did=1619205491&sid=1&Fmt=2&clientId=8424&RQT=309&VName=PQD.

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IWATA, HISASHI, MINORU UEDA, KAZUHIKO MERA, and HIDEKI MIZUTANI. "A STUDY OF THE BONE MORPHOGENETIC PROTEIN DERIVED FROM BOVINE DEMINERALIZED DENTIN MATRIX." Nagoya University School of Medicine, 1996. http://hdl.handle.net/2237/16100.

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Books on the topic "BMP [Bone morphogenic protein]"

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Li, Ivan Wing Sum. Regulation of bone matrix protein expression by recombinant human osteogenic protein-1 (RHOP-1; BMP-7) at different stages of osteogenic differentiation in fetal rat calvarial cells. National Library of Canada, 1995.

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Litwack, Gerald. Bone Morphogenic Protein. Elsevier Science & Technology Books, 2015.

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Bone Morphogenic Protein. Elsevier, 2015. http://dx.doi.org/10.1016/s0083-6729(15)x0004-5.

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Book chapters on the topic "BMP [Bone morphogenic protein]"

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Blokhuis, Taco J., Peter Patka, Henk J. Th M. Haarman, and Lex R. Giltaij. "Osteogenic protein-1 (OP-1, BMP-7) for stimulation of healing of closed fractures: evidence based medicine and pre-clinical experience." In Bone Morphogenetic Proteins. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8121-0_7.

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Harris, Stephen E., Wuchen Yang, Jelica Gluhak-Heinrich, et al. "The role and mechanisms of bone morphogenetic protein 4 and 2 (BMP-4 and BMP-2) in postnatal skeletal development." In Bone Morphogenetic Proteins: From Local to Systemic Therapeutics. Birkhäuser Basel, 2008. http://dx.doi.org/10.1007/978-3-7643-8552-1_10.

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Hartwig, C. H., G. Herr, C. Boll, and W. Küsswetter. "Knocheninduktion durch Beschichtung metallischer Prüfkörper mit Bone Morphogenetic-Protein (BMP)." In Hefte zur Zeitschrift „Der Unfallchirurg“. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-85198-8_56.

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Aykul, Senem, and Erik Martinez-Hackert. "High-Throughput, Biosensor-Based Approach to Examine Bone Morphogenetic Protein (BMP)–Receptor Interactions." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8904-1_5.

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Newman, Jenna, Rachel NeMoyer, Andrew Zloza, and John Langenfeld. "Double-Humanized Mouse Model to Study Bone Morphogenetic Protein (BMP) Signaling in Tumor Xenografts." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8904-1_19.

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Nickel, Joachim, Matthias Dreyer, and Walter Sebald. "Deciphering the binding code of BMP-receptor interaction." In Bone Morphogenetic Proteins. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8121-0_4.

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Rose, Tim, H. Peng, H. C. Shen, et al. "Die Rolle des Zelltyps für die ex-vivo Gentherapie bei der zellvermittelten Applikation von Bone Morphogenic Protein (BMP) zur Knochenneubildung." In Deutsche Gesellschaft für Chirurgie. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-19024-7_3.

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Kamegai, A., T. Tanabe, N. Shimamura, S. Kumasa, K. Yamada, and M. Mori. "Immunohistochemical and Enzyme Histochemical Studies in Bone Formation Induced by Bone Morphogenetic Protein (BMP) in Mouse Muscle Tissue." In Mechanisms and Phylogeny of Mineralization in Biological Systems. Springer Japan, 1991. http://dx.doi.org/10.1007/978-4-431-68132-8_19.

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Cook, Stephen D., and David C. Rueger. "Preclinical models of recombinant BMP induced healing of orthopedic defects." In Bone Morphogenetic Proteins. Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8121-0_6.

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Nolan, Kristof, and Thomas B. Thompson. "BMP and BMP Regulation: Structure and Function." In Bone Morphogenetic Proteins: Systems Biology Regulators. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47507-3_4.

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Conference papers on the topic "BMP [Bone morphogenic protein]"

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Drexler, S., C. Chai, H. Gaitantzi, M. Ebert, and K. Breitkopf-Heinlein. "Fettlebererkrankung: protektive Rolle von Bone Morphogenetic Protein (BMP)-9?" In Viszeralmedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1695352.

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Shim, Jin-Hyung, Jong Young Kim, Kyung Shin Kang, Jung Kyu Park, Sei Kwang Hahn, and Dong-Woo Cho. "Development of HA-PLGA Scaffold Encapsulating Intact BMP-2 Using Solid Freeform Fabrication Technology." In ASME 2011 International Manufacturing Science and Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/msec2011-50259.

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Tissue engineering is an interdisciplinary field that focuses on restoring and repairing tissues or organs. Cells, scaffolds, and biomolecules are recognized as three main components of tissue engineering. Solid freeform fabrication (SFF) technology is required to fabricate three-dimensional (3D) porous scaffolds to provide a 3D environment for cellular activity. SFF technology is especially advantageous for achieving a fully interconnected, porous scaffold. Bone morphogenic protein-2 (BMP-2), an important biomolecule, is widely used in bone tissue engineering to enhance bone regeneration acti
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Yanoso, Laura, Justin Jacobson, Tulin Dadali, David Reynolds, and Hani Awad. "Evaluation of Polylactic Acid/Beta-Tricalcium Phosphate Scaffolds as Segmental Bone Graft Substitutes." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192978.

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The use of processed structural allografts for treatment of massive segmental defects in long bones can be complicated by poor incorporation and remodeling of the devitalized graft, foreign-body reaction and micro-damage accumulation which often leads to catastrophic graft failure [1]. It is therefore useful to develop a bioengineered, biodegradable scaffold that is able to stimulate healing of the defect region. The use of bioengineered scaffolds has been limited due to their poor mechanical strength that does not permit withstanding large in vivo loads and due to their poor osteoinductive pr
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Sucosky, Philippe, Kartik Balachandran, Hanjoong Jo та Ajit P. Yoganathan. "Altered Shear Stress Stimulates Upregulation of Endothelial VCAM-1 and ICAM-1 in a BMP-4- and TGF-β1-Dependent Pathway". У ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204693.

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Inflammation and calcification are common features of aortic valve (AV) diseases [1]. AV diseases preferentially occur in the aortic side of the valvular leaflets where they are exposed to complex and unstable hemodynamic conditions [2]. The reasons for this side-specific response, potentially associated with the local shear stress environment, are not completely understood. In addition, while it has been shown that exposure of vascular endothelial cells to oscillatory shear stress induces inflammatory responses by bone morphogenic protein (BMP)-4-dependent mechanisms [3], it is not clear whet
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Ludwig, A., H. Gaitantzi, C. König, HG Augustin, M. Ebert, and K. Breitkopf-Heinlein. "Rolle von bone morphogenetic protein (BMP)-9 bei der Regulation des hepatischen Eisenhaushalts." In Viszeralmedizin 2017. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1605074.

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Glynn, SF, MT Walsh, and RW Costello. "Eosinophil Mediated Airway Remodelling and the Bone Morphogenetic Protein (BMP) Pathway in Asthma." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a6325.

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Leinhäuser, Ines, Ines Höfig, Natasa Anastasov, et al. "Abstract 4059: The bone morphogenic protein 7 (Bmp7) plays a pro-tumorigenic role in pheochromocytoma." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4059.

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Hu, Jun, Bin Tian, David T. Fritz, and Melissa B. Rogers. "Using emerging genome data to identify conserved bone morphogenetic protein (Bmp) 2 gene expression mechanisms." In the 1st international workshop. ACM Press, 2006. http://dx.doi.org/10.1145/1183535.1183541.

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Karagiannis, George S., Natasha Musrap, and Eleftherios P. Diamandis. "Abstract 4923: Myofibroblasts induce specific epithelial-to-mesenchymal transition (EMT) patterns in colorectal cancer cells by enhanced secretion of bone morphogenic protein (BMP) inhibitors." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4923.

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Kemmis, Carly M., and Diane R. Wagner. "FAK, SMAD and MAPK Pathways Diverge During Osteogenic and Chondrogenic Differentiation of Adipose-Derived Mesenchymal Cells." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206474.

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Adipose-derived mesenchymal cells (AMCs) are a promising cell source for orthopaedic tissue engineering applications due to their accessibility and multi-lineage potential [1]. However, future use in bone and cartilage regeneration requires a comprehensive understanding of the pathways driving AMCs to osteogenic and chondrogenic lineages. We have previously demonstrated the dual function of a single medium containing bone morphogenetic protein-6 (BMP-6) on differentiation of AMCs; in the presence of BMP-6, monolayer culture induces osteogenic differentiation while pellet culture stimulates cho
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