Relevant bibliographies by topics / Body axis formation

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Body axis formation'

Author: Grafiati
Published: 4 June 2021
Last updated: 9 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Body axis formation.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Body axis formation"

1

Bénazéraf, Bertrand, and Olivier Pourquié. "Formation and Segmentation of the Vertebrate Body Axis." Annual Review of Cell and Developmental Biology 29, no. 1 (October 6, 2013): 1–26. http://dx.doi.org/10.1146/annurev-cellbio-101011-155703.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Takebayashi-Suzuki, Kimiko, and Atsushi Suzuki. "Intracellular Communication among Morphogen Signaling Pathways during Vertebrate Body Plan Formation." Genes 11, no. 3 (March 24, 2020): 341. http://dx.doi.org/10.3390/genes11030341.

Full text
Abstract:
During embryonic development in vertebrates, morphogens play an important role in cell fate determination and morphogenesis. Bone morphogenetic proteins (BMPs) belonging to the transforming growth factor-β (TGF-β) family control the dorsal–ventral (DV) patterning of embryos, whereas other morphogens such as fibroblast growth factor (FGF), Wnt family members, and retinoic acid (RA) regulate the formation of the anterior–posterior (AP) axis. Activation of morphogen signaling results in changes in the expression of target genes including transcription factors that direct cell fate along the body axes. To ensure the correct establishment of the body plan, the processes of DV and AP axis formation must be linked and coordinately regulated by a fine-tuning of morphogen signaling. In this review, we focus on the interplay of various intracellular regulatory mechanisms and discuss how communication among morphogen signaling pathways modulates body axis formation in vertebrate embryos.
APA, Harvard, Vancouver, ISO, and other styles
3

Mongera, Alessandro, Arthur Michaut, Charlène Guillot, Fengzhu Xiong, and Olivier Pourquié. "Mechanics of Anteroposterior Axis Formation in Vertebrates." Annual Review of Cell and Developmental Biology 35, no. 1 (October 6, 2019): 259–83. http://dx.doi.org/10.1146/annurev-cellbio-100818-125436.

Full text
Abstract:
The vertebrate anteroposterior axis forms through elongation of multiple tissues during embryogenesis. This process is based on tissue-autonomous mechanisms of force generation and intertissue mechanical coupling whose failure leads to severe developmental anomalies such as body truncation and spina bifida. Similar to other morphogenetic modules, anteroposterior body extension requires both the rearrangement of existing materials—such as cells and extracellular matrix—and the local addition of new materials, i.e., anisotropic growth, through cell proliferation, cell growth, and matrix deposition. Numerous signaling pathways coordinate body axis formation via regulation of cell behavior during tissue rearrangements and/or volumetric growth. From a physical perspective, morphogenesis depends on both cell-generated forces and tissue material properties. As the spatiotemporal variation of these mechanical parameters has recently been explored in the context of vertebrate body elongation, the study of this process is likely to shed light on the cross talk between signaling and mechanics during morphogenesis.
APA, Harvard, Vancouver, ISO, and other styles
4

Loucks, Evyn J., and Sara C. Ahlgren. "Disruption of normal body axis formation after teratogen exposure." Developmental Biology 306, no. 1 (June 2007): 409. http://dx.doi.org/10.1016/j.ydbio.2007.03.628.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Ueda, Minako, and Frédéric Berger. "New cues for body axis formation in plant embryos." Current Opinion in Plant Biology 47 (February 2019): 16–21. http://dx.doi.org/10.1016/j.pbi.2018.08.005.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Savard, Pierre. "Body axis determination during early development in amphibians." Biochemistry and Cell Biology 70, no. 10-11 (October 1, 1992): 875–91. http://dx.doi.org/10.1139/o92-136.

Full text
Abstract:
The specification of the main axes of the body is a phenomenon based on cell communication and is among the early crucial events of embryonic development. Upon fertilization, the amphibian egg reorganizes its cytoplasmic content, leading to the establishment of the future dorsal–ventral axis of the body. Heterogeneous distribution of maternal components confers cellular regionalization after only a few mitoses. Development up to the 4000-cell stage proceeds almost entirely on maternal materials, and during this period there is remodeling of the chromatin to set up specific gene expression in various regions of the embryo. The zygote at this stage has already undertaken cellular interactions leading to mesoderm formation and regionalization. Dorsal mesodermal components then induce the formation of the Spemann's organizer, a structure directly involved in the specification of the anterior–posterior axis of the embryo (head to tail). Molecular analysis of these phenomena has allowed the identification of growth-factor-like and transcription-factor-like proteins that have characteristics typical of specification factors. We will review the recent advances on these molecules and will also discuss the putative role of retinoic acid as a posteriorizing agent.Key words: chromatin remodeling, cellular regionalization, homeobox, inducing factor, retinoic acid.
APA, Harvard, Vancouver, ISO, and other styles
7

Yan, Lu, Jing Chen, Xuechen Zhu, Jiawei Sun, Xiaotong Wu, Weimin Shen, Weiying Zhang, Qinghua Tao, and Anming Meng. "Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates." Science 362, no. 6417 (November 22, 2018): eaat1045. http://dx.doi.org/10.1126/science.aat1045.

Full text
Abstract:
The vertebrate body is formed by cell movements and shape change during embryogenesis. It remains undetermined which maternal signals govern the formation of the dorsal organizer and the body axis. We found that maternal depletion of huluwa, a previously unnamed gene, causes loss of the dorsal organizer, the head, and the body axis in zebrafish and Xenopus embryos. Huluwa protein is found on the plasma membrane of blastomeres in the future dorsal region in early zebrafish blastulas. Huluwa has strong dorsalizing and secondary axis–inducing activities, which require β-catenin but can function independent of Wnt ligand/receptor signaling. Mechanistically, Huluwa binds to and promotes the tankyrase-mediated degradation of Axin. Therefore, maternal Huluwa is an essential determinant of the dorsal organizer and body axis in vertebrate embryos.
APA, Harvard, Vancouver, ISO, and other styles
8

TILTON, F., J. LADU, M. VUE, N. ALZARBAN, and R. TANGUAY. "Dithiocarbamates have a common toxic effect on zebrafish body axis formation." Toxicology and Applied Pharmacology 216, no. 1 (October 1, 2006): 55–68. http://dx.doi.org/10.1016/j.taap.2006.04.014.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Hahn, M., and H. Jäckle. "Drosophila goosecoid participates in neural development but not in body axis formation." EMBO Journal 15, no. 12 (June 1996): 3077–84. http://dx.doi.org/10.1002/j.1460-2075.1996.tb00670.x.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Fan, M. J., and S. Y. Sokol. "A role for Siamois in Spemann organizer formation." Development 124, no. 13 (July 1, 1997): 2581–89. http://dx.doi.org/10.1242/dev.124.13.2581.

Full text
Abstract:
The vertebrate body plan is specified in the early embryo through the inductive influence of the organizer, a special region that forms on the dorsalmost side of the embryo at the beginning of gastrulation. In Xenopus, the homeobox gene Siamois is activated prior to gastrulation in the area of organizer activity and is capable of inducing a secondary body axis when ectopically expressed. To elucidate the function of endogeneous Siamois in dorsoventral axis formation, we made a dominant repressor construct (SE) in which the Siamois homeodomain was fused to an active repression domain of Drosophila engrailed. Overexpression of 1–5 pg of this chimeric mRNA in the early embryo blocks axis development and inhibits activation of dorsal, but not ventrolateral, marginal zone markers. At similar expression levels, SE proteins with altered DNA-binding specificity do not have the same effect. Coexpression of mRNA encoding wild-type Siamois, but not a mutated Siamois, restores dorsal development to SE embryos. Furthermore, SE strongly blocks axis formation triggered by beta-catenin but not by the organizer product noggin. These results suggest that Siamois function is essential for beta-catenin-mediated formation of the Spemann organizer, and that Siamois acts prior to noggin in specifying dorsal development.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Body axis formation"

1

Rho, Ho Kyung. "A Systems Level Analysis of the Transcription Factor FoxN2/3 and FGF Signal Transduction in Sea Urchin Larval Skeleton Development and Body Axis Formation." Diss., 2011. http://hdl.handle.net/10161/3819.

Full text
Abstract:

Specification and differentiation of a cell is accomplished by changing its gene expression profiles. These processes require temporally and spatially regulated transcription factors (TFs), to induce the genes that are necessary to a specific cell type. In each cell a set of TFs interact with each other or activate their targets; as development progresses, transcription factors receive regulatory inputs from other TFs and a complex gene regulatory network (GRN) is generated. Adding complexity, each TF can be regulated not only at the transcriptional level, but also by translational, and post-translational mechanisms. Thus, understanding a developmental process requires understanding the interactions between TFs, signaling molecules and target genes which establish the GRN.

In this thesis, two genes, FoxN2/3, a TF and FGFR1, a component of the FGF signaling pathway are investigated. FoxN2/3 and FGFR1 have different mechanisms that function in sea urchin development; FoxN2/3 regulates gene expression and FGFR1 changes phosphorylation of target proteins. However, their ultimate goals are the same: changing the state of an earlier GRN into the next GRN state.

First, we characterize FoxN2/3 in the primary mesenchyme cell (PMC) GRN. Expression of foxN2/3 begins in the descendants of micromeres at the early blastula stage; and then is lost from PMCs at the mesenchyme blastula stage. foxN2/3 expression then shifts to the secondary mesenchyme cells (SMCs) and later to the endoderm. Here we show that, Pmar1, Ets1 and Tbr are necessary for activation of foxN2/3 in the descendants of micromeres. The later endomesoderm expression is independent of the earlier expression of FoxN2/3 in micromeres and independent of signals from PMCs. FoxN2/3 is necessary for several steps in the formation of larval skeleton. A number of proteins are necessary for skeletogenesis, and early expression of at least several of these is dependent on FoxN2/3. Furthermore, knockdown (KD) of FoxN2/3 inhibits normal PMC ingression. PMCs lacking FoxN2/3 protein are unable to join the skeletogenic syncytium and they fail to repress the transfating of SMCs into the skeletogenic lineage. Thus, FoxN2/3 must be present for the PMC GRN to control normal ingression, expression of skeletal matrix genes, prevention of transfating, and control fusion of the PMC syncytium.

Second, we show that the FGF-FGFR1 signaling is required for the oral-aboral axis formation in the sea urchin embryos. Without FGFR1, nodal is induced in all of the cells at the early blastula stage and this ectopic expression of nodal requires active p38 MAP kinase. The loss of oral restriction of nodal expression results in the abnormal organization of PMCs and the larval skeleton; it also induces ectopic expression of oral-specific genes and represses aboral-specific genes. The abnormal oral-aboral axis formation also affected fgf and vegf expression patterns; normally these factors are expressed in two restricted areas of the ectoderm between the oral and the aboral side, but when FGFR1 is knocked down, Nodal expands, and in response the expression of the FGF and VEGF ligands expands, and this in turn affects the abnormal organization of larval skeleton.


Dissertation
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Body axis formation"

1

Zagórska-Marek, Beata. "Mirror Symmetry of Life." In Current Topics in Chirality - From Chemistry to Biology. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96507.

Full text
Abstract:
Functioning in the Earth gravity field imposes on living organisms a necessity to read directions. The characteristic feature of their bodies, regardless unicellular or multicellular, is axial symmetry. The development of body plan orchestrated by spatiotemporal changes in gene expression patterns is based on formation of the vertical and radial axes. Especially for immobile plants, anchored to the substrate, vertical axis is primary and most important. But also in animals the primary is the axis, which defines the anterior and posterior pole of the embryo. There are many little known chiral processes and structures that are left- or right oriented with respect to this axis. Recent developments indicate the role of intrinsic cell chirality that determines the direction of developmental chiral processes in living organisms. The still enigmatic events in cambia of trees and handedness of phyllotaxis as well as plant living crystals are in focus of the chapter.
APA, Harvard, Vancouver, ISO, and other styles
2

Scholtz, Gerhard. "Duplicated, Twisted, and in the Wrong Place." In Developmental Biology and Larval Ecology, 113–42. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190648954.003.0004.

Full text
Abstract:
The study of malformations is an important tool to understand mechanisms and causes of development and regeneration. Moreover, malformations indicate the morphological potential of living beings. Hence, a deeper understanding of how, to what degree, and why organismal structures can deviate from their normal expression is interesting in an evolutionary and ecological context. Like other arthropods, and animals in general, crustaceans show a certain variety of naturally occurring malformations of different body parts. This review is restricted to those that affect the axes of appendages and the trunk. Hence, the various patterns of axis distortion are described and classified. At the general level, malformations concerning limbs are discriminated from those that alter other body outgrowths and those that affect the pattern of the trunk. Among malformation of limbs and other body appendages, misplaced structures, fissions, and fusions are classified. Conjoined twins and distorted body segments are the main features of trunk malformations. The putative causes of malformations are discussed with respect to comparative and experimental approaches. Furthermore, gene expression studies, theories, and models, such as Hans Meinhardt’s Boundary Model, are applied to explain malformations at the level of pattern formation. Apparently, many malformations are not genetic mutations and thus not inheritable, but are instead the result of distortions during early development and regeneration artifacts based on injuries, high temperature, and toxic substances. Compared with other arthropod groups, there are very few experimental studies addressing malformations in crustaceans. Hence, the causes for specific patterns of deformities remain largely obscure.
APA, Harvard, Vancouver, ISO, and other styles
3

"Different Shades of Early Shamanism in the Upper Amazon." In Archaeological Interpretations, edited by Francisco Valdez, 111–44. University Press of Florida, 2020. http://dx.doi.org/10.5744/florida/9780813066448.003.0006.

Full text
Abstract:
Recent archaeological research in the upper Amazon region, on the frontier between Ecuador and Peru, has discovered a new pre-Columbian culture, now known as the Mayo Chinchipe-Marañón society. The most important site that has been studied until now is Santa Ana–La Florida (SALF), located in Palanda (Zamora Chinchipe province, Ecuador), where an Early Formative period ceremonial center has been studied for over a decade. This site has been occupied for over 5000 years. The ceremonial center has an architectural layout centered around a sunken plaza, with two platforms placed at each end on an east-west axis. The eastern platform served as the base of a round structure that contained evidence of ritual activities. Several tombs have been located in the body of the platform. One, however, stands out for its extraordinary paraphernalia, which suggests the presence of a very relevant individual: a shaman.
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Body axis formation"

1

Tilki, Umut, Ismet Erkmen, and Aydan M. Erkmen. "Imitation of Human Body Poses by the Formation Control of a Fluidic Swarm." In ASME 2012 11th Biennial Conference on Engineering Systems Design and Analysis. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/esda2012-82903.

Full text
Abstract:
Imitation learning is one of the forms of social learning that enables the human or robot agents to learn new skills. The knowledge acquired for imitation can be basically represented as action mapping based on “organ matching” which determines the correspondence between imitator and imitatee, if the imitator and the demonstrator share the same embodiment. In this paper, we aim at imitation of two system with totally different dynamics, imitating each other, where any correspondence is missing. Towards this aim, we adopt a case where the imitator is a fluidic system which dynamics is totally different than the imitatee, that is a human performing different body poses. Our work proposes the fluidics formation control of fluid particles where the formation results from the imitation of observed human body poses. Fluidic formation control layer is responsible of assigning the correct fluid parameters to the swarm formation layer according to the body poses adopted by the human performer. The movement of the fluid particles is modeled using the Smoothed Particle Hydrodynamics (SPH) which is a particle based Lagrangian method for simulation of fluid flows. The region based controller first extract the human body parts generating the regions where the attention is attracted by the imitatee and fits an appropriate ellipses to delimite boundaries of those regions. The ellipse parameters such as center of the ellipses, eccentricity, length of the major and minor axis etc. are used by the fludic layer in order to generate human body poses. This paper introduces our technique and demonstrates the imitation performance of our system.
APA, Harvard, Vancouver, ISO, and other styles
2

Lakeh, Reza Baghaei, and Majid Molki. "Heat Transfer Enhancement in Rectangular Channels Using a Corona Jet Caused by Longitudinal Flat Electrodes." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62591.

Full text
Abstract:
Heat transfer in rectangular channels can be significantly enhanced by formation of secondary flows. Secondary flow fields appear within the channels and influence the boundary layer growth and improve the convective heat transfer. When a high potential is applied to two electrodes, the consequent high electric field in the gap between the electrodes may exceed the partial break-down limit of the gas molecules. The neutral gas molecules are ionized close to the emitting electrode and accelerate in the direction of the electric field. The accelerating ions impose an electric body-force to the gas and induce a bulk flow. Depending on the location and geometry of the electrodes, the electrically-induced flow field might have different specifications. If the electrodes are laid on the opposite walls of channel and extended in the longitudinal direction, the electric body-force would cause a secondary flow on the cross section of the channel. The electrically-induced flow field disturbs the boundary layer and enhances the convective heat transfer coefficient. However, the enhancement level is more remarkable in natural convection. In this study, the influence of a corona jet on heat transfer in rectangular channels with flat and longitudinal electrodes will be studied. The emitting and collecting electrodes are metallic strips attached to opposite walls of the channel and are extended along the axis of the channel. The electric field governing equations are solved numerically using finite-volume method and the third-order QUICK scheme is utilized for discretization of the charge fluxes. The distribution of electric field and charge density on the cross section of the channel is obtained to find the electric body-force at each point. In the presence of electric and buoyancy forces, the momentum and energy equations are solved to determine the level of enhancement of convective heat transfer using corona discharge.
APA, Harvard, Vancouver, ISO, and other styles
3

Alameddine, A. "Arterial Flow Resonance Biodynamics Resolves Plaques Buildup: Theoretical Development." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62337.

Full text
Abstract:
Based on a new scientifically-engineered approach, we conjecture that adequate quantities of specific classes of nutrients (chemical agents) to accompany cholesterol intensive meals disentangles precipitation, hinders blockade, and effectively reduces buildup of plaques on inner arterial walls. Specific chemical agents lead to formation of low-frequency vibrating boundary layers at the arterial walls. The axes of these differential vibrations are positioned orthogonal to the arterial walls. Once vibrations reach resonance at the quantum level, they obstruct plaques precipitation and clinging at the cellular level by resonance bioportation magnificative channeling between the two levels. The resonance creates the physical equivalence of perturbative “slip-zone” on the inner arterial walls. Additionally, arterial resonance in specific modes, can act as a mechanical harmonic hammer that could also destabilize excessive clotting (thrombosis). In this paper, we develop and state below the theoretical bioportation fluid dynamics basis underlying our new biodynamic bioportation engineering model that is sufficient to build preventive boundary layer resonance around the inner of arterial walls to reduce and prevent plaques buildup. We start developing the mathematics, biomechanics, and biodynamic bioportation of the presented model. We build its conceptual and theoretical skeletal framework and show some challenging theoretical implications of our new hidden science, such as our fluid-bioportation dynamic formulation. We present the scientific fundamentals of our theoretical development and show how their base parks at the quantum level. It functions from concepts in the femto-world of quantum engineering. Its biomechanics & biodynamics are activated at the nano bioengineering energy levels in a bottom-up propagation hierarchy. The energy state and momentum determined by the density and flux of the oscillating source of vibrations at the quantum level is proportional to agents’ concentrations in the blood. The oscillating boundary resonance at the quantum level is magnificative thru a transient naturally resonant turbulent wave asymptotically constructed from the behavior of the transverse stress-energy-momentum tensor field T of the fluid (blood) vector field V at the macro-cellular level. The resonant boundary surface turbulence provides a “shake-off” motion to prevent plaques precipitation on arterial inner walls. A condition for the generation of such dynamic bioportation for the resonant surface boundary is presented mathematically. This natural body-generated phenomenon is classified within a new class of biodynamics we shall call “Fluidobioportation” dynamics. If at times, the class of special nutrients is unavailable to naturally trigger this phenomenon, the same could be induced by intake of specific chemical agents. At the macro-level, the bioportation process is engineeringly-sensed as an ultra-light energy-momentum turbulent wave generated by arterial boundary surface resonance rooted at the micro-level. While turbulent wave biodynamics could be shown to analytically and geometrically disallow plaques precipitation, it also has a potential to destabilize clot formation. Continuity and extension of this process may also lead to gradual systematic “shave off” of existing plaques accumulations and reduction of clotting.
APA, Harvard, Vancouver, ISO, and other styles
4

Payton, Lewis N. "Low Speed Orthogonal Machining of Pre-Heated FCC:BCC Alloys." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-71408.

Full text
Abstract:
Cocquilhat’s first documented (1851) how heat in a tool shortens the life of the tool. Research since his time has generally concluded that the tool gives up a relatively higher percentage of it’s “cold hardness and toughness” as compared to the work stock. This paper looks at the previously unstudied advantages/disadvantages which may be gained by pre-heating the work stock to a relatively modest temperature, thereby preferentially shifting the ratio/percentages back toward the tool. A widely-used body centered cubic (BCC) steel and a widely-used face centered cubic (FCC) aluminum were chosen to test common commercially machined crystalline structures. The materials were heat treated and/or aged to provide various levels of hardness within the crystalline structures. The selection of two cutting speeds, two levels of cut and three tool rake angles completed the factor level combinations chosen for the study. Parts were preheated immediately prior to the machining operations with an additional resistance heater mounted in the work holder to maintain the temperatures during the trial run. Tensile specimens of all the samples were undertaken to establish the cold working flow stress values of the materials tested. Machining was conducted in a specially modified Cincinnati Horizontal Milling machine using an improved Videographic Quick Stop Device (VQSD) to capture the geometry of the cutting formation simultaneously with the forces in the X, Y and Z-axes using a standard Kistler force plate dynamometer. Utilizing the VQSD greatly increases the number of replicates available for statistical analysis by the metal cutting researcher. This allows for comprehensive multivariate analysis of the data with high confidence (> 95%) in the obtained results. Forces and geometry were collected and analyzed. Wear was measured on the face of each tool using surface profilometers and white light microscopy. The specific horsepower (HPs), also known as the specific cutting energy, normal force (N), and wear rate data indicated there is a definite advantage to be had in pre-heating the workpiece by even a modest amount. In fact, the temperature was a significant prime factor (p-value <= 0.0001, Fstat > 5 with 95% certainty) in all factor level combinations. It was often ranked as the primary number one factor or the number two ranked factor. Many interactions with the temperature were also significant. This, combined with improved tool cooling methods, should result in all tools living a longer time while undergoing less chatter and/or deflection.
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Body axis formation' for particular source types:
Journal articles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography