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Journal articles on the topic 'Bone graft extender'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Vestermark, Marianne T., Ellen-Margrethe Hauge, Kjeld Soballe, Joan E. Bechtold, Thomas Jakobsen, and Jorgen Baas. "Strontium doping of bone graft extender." Acta Orthopaedica 82, no. 5 (2011): 614–21. http://dx.doi.org/10.3109/17453674.2011.618909.

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2

Lee, Jae Hyup, Mi Young Ryu, Hae-Ri Baek, Kyung Mee Lee, Jun-Hyuk Seo, and Hyun-Kyung Lee. "Fabrication and Evaluation of Porous Beta-Tricalcium Phosphate/Hydroxyapatite (60/40) Composite as a Bone Graft Extender Using Rat Calvarial Bone Defect Model." Scientific World Journal 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/481789.

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Beta-tricalcium phosphate (β-TCP) and hydroxyapatite (HA) are widely used as bone graft extenders due to their osteoconductivity and high bioactivity. This study aims to evaluate the possibility of using porous substrate with composite ceramics (β-TCP: HA = 60% : 40%, 60TCP40HA) as a bone graft extender and comparing it with Bio-Oss. Interconnectivity and macroporosity ofβ-TCP porous substrate were 99.9% and 83%, respectively, and the macro-porosity of packed granule after crushing was 69%. Calvarial defect model with 8 mm diameter was generated with male Sprague-Dawley rats and 60TCP40HA was

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3

Keränen, P., A. Itälä, J. Koort, et al. "Bioactive Glass Granules as Extender of Autogenous Bone Grafting in Cementless Intercalary Implant of the Canine Femur." Scandinavian Journal of Surgery 96, no. 3 (2007): 243–51. http://dx.doi.org/10.1177/145749690709600310.

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Background and Aims: Ceramic bone graft substitutes have a potential to be used as replacement of allogeneic bone grafting and, under optimal distribution of particle size, they may even provide mechanical support. The current study examined the efficacy of bioactive glass granules as an extender of autogenous bone grafting in a segmental bone replacement model of the canine femur. Material and Method: A 16 mm long segment of the femur shaft was bilaterally replaced with an intercalary titanium implant in eight animals. The implant had cementless grooved proximal and distal stems. In one leg,

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4

McGuire, Robert, Leslie Pilcher, and Joseph Dettori. "Lumbar posterolateral fusion with local bone graft plus bone extender compared with iliac crest bone graft: a systematic review." Evidence-Based Spine-Care Journal 2, no. 02 (2011): 35–40. http://dx.doi.org/10.1055/s-0030-1267103.

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5

Garin, Christophe, and Séverine Boutrand. "Natural hydroxyapatite as a bone graft extender for posterolateral spine arthrodesis." International Orthopaedics 40, no. 9 (2016): 1875–82. http://dx.doi.org/10.1007/s00264-016-3140-4.

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6

Li, Guanbao, Pinquan Li, Qiuan Chen, Hnin Ei Thu, and Zahid Hussain. "Current Updates on Bone Grafting Biomaterials and Recombinant Human Growth Factors Implanted Biotherapy for Spinal Fusion: A Review of Human Clinical Studies." Current Drug Delivery 16, no. 2 (2018): 94–110. http://dx.doi.org/10.2174/1567201815666181024142354.

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Background:Owing to their great promise in the spinal surgeries, bone graft substitutes have been widely investigated for their safety and clinical potential. By the current advances in the spinal surgery, an understanding of the precise biological mechanism of each bone graft substitute is mandatory for upholding the induction of solid spinal fusion.Objective:The aim of the present review is to critically discuss various surgical implications and level of evidence of most commonly employed bone graft substitutes for spinal fusion.Method:Data was collected via electronic search using “PubMed”,

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7

Blom, A. W., B. Grimm, A. W. Miles, J. L. Cunningham, and I. D. Learmonth. "Subsidence in impaction grafting: The effect of adding a ceramic bone graft extender to bone." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 216, no. 4 (2002): 265–70. http://dx.doi.org/10.1243/09544110260138754.

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The incidence of revision total hip arthroplasty is increasing dramatically and the associated demand for allograft bone is likely to exceed the available supply. In addition, allograft presents potential problems with regard to infection, antigenicity, availability, reproducibility and cost. It is therefore desirable to develop an alternative to allograft. This study investigated BoneSave, a porous tricalcium phosphate-hydroxyapatite ceramic for use in impaction grafting of the femur at revision total hip arthroplasty. The findings of an in vitro mechanical study comparing the initial stabili

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8

Lewandrowski, Kai-Uwe, David D. Hile, Benjamin M. J. Thompson, Donald L. Wise, William W. Tomford, and Debra J. Trantolo. "Quantitative Measures of Osteoinductivity of a Porous Poly(propylene fumarate) Bone Graft Extender." Tissue Engineering 9, no. 1 (2003): 85–93. http://dx.doi.org/10.1089/107632703762687564.

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9

Chedid, Mokbel K., Kelly M. Tundo, Jon E. Block, and Jeffrey M. Muir. "Hybrid Biosynthetic Autograft Extender for Use in Posterior Lumbar Interbody Fusion: Safety and Clinical Effectiveness." Open Orthopaedics Journal 9, no. 1 (2015): 218–25. http://dx.doi.org/10.2174/1874325001509010218.

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Autologous iliac crest bone graft is the preferred option for spinal fusion, but the morbidity associated with bone harvest and the need for graft augmentation in more demanding cases necessitates combining local bone with bone substitutes. The purpose of this study was to document the clinical effectiveness and safety of a novel hybrid biosynthetic scaffold material consisting of poly(D,L-lactide-co-glycolide) (PLGA, 75:25) combined by lyophilization with unmodified high molecular weight hyaluronic acid (10-12% wt:wt) as an extender for a broad range of spinal fusion procedures. We retrospect

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10

van Haaren, E. H., T. H. Smit, K. Phipps, P. I. J. M. Wuisman, G. Blunn, and I. C. Heyligers. "Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery." Journal of Bone and Joint Surgery. British volume 87-B, no. 2 (2005): 267–71. http://dx.doi.org/10.1302/0301-620x.87b2.14749.

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11

Arts, J. J. C., J. W. M. Gardeniers, M. L. M. Welten, N. Verdonschot, B. W. Schreurs, and P. Buma. "TCP-HA Granules and Impacted Morselized Cancellous Bone Graft Mixes for Acetabular Reconstruction with the Bone Impaction Grafting Technique. A Loaded and Critical Sized Defect Model in the Goat." Key Engineering Materials 284-286 (April 2005): 869–72. http://dx.doi.org/10.4028/www.scientific.net/kem.284-286.869.

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With the bone impaction grafting technique, a 50/50 volume mix of morselized cancellous bone (MCB) with TCP-HA granules was used to reconstruct a critical sized acetabular defect in the goat. The biological activity of the MCB/TCP-HA mix was assessed after 15 weeks. Defects filled with 100% MCB, currently the gold standard for this technique, were used as controls. In the 100% MCB defects, a new trabecular bone structure was found in which scarce incorporated remnants of the original graft material were present. In the MCB/TCP-HA defects, MCB was also resorbed or incorporated into new bone. De

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12

Putzer, David, Johannes Fuchs, Débora Coraça-Huber, Christoph Ammann, Michael Liebensteiner, and Michael Nogler. "BAG-S53P4 as an Additive to Bone Allografts: A Laboratory Study Using an Uniaxial Compression Test." J Orthop Res 33 (June 12, 2015): 1875–79. https://doi.org/10.1002/jor.22953.

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ABSTRACT: We want to address the clinical issue of too sparse supply of allograft in total hip replacement and ambitions of controlling the grain size distribution. Bioglass BAG-S53P4 was evaluated as a bone graft additive to chemically treated allografts with controlled grain size distribution. Allografts were chemically cleaned (CG) and mixed with BAG-S53P4 additive (BG) for comparison. All samples were compacted with a dropped weight apparatus and then underwent a uniaxial compression test. The yield limit was determined by a uniaxial compression test and density was recorded while flowabil

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13

Kim, Hyoungmin, Choon-Ki Lee, Jin-Sup Yeom, Jae-Hyup Lee, Ki-Ho Lee, and Bong-Soon Chang. "The efficacy of porous hydroxyapatite bone chip as an extender of local bone graft in posterior lumbar interbody fusion." European Spine Journal 21, no. 7 (2011): 1324–30. http://dx.doi.org/10.1007/s00586-011-2092-z.

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14

Bortolin, Monica, Carlo L. Romanò, Alessandro Bidossi, Elena De Vecchi, Roberto Mattina, and Lorenzo Drago. "BAG-S53P4 as bone graft extender and antimicrobial activity against gentamicin- and vancomycin-resistant bacteria." Future Microbiology 13, no. 5 (2018): 525–33. http://dx.doi.org/10.2217/fmb-2016-0171.

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15

Howie, Donald W., Margaret A. McGee, Stuart A. Callary, et al. "A Preclinical Study of Stem Subsidence and Graft Incorporation After Femoral Impaction Grafting Using Porous Hydroxyapatite as a Bone Graft Extender." Journal of Arthroplasty 26, no. 7 (2011): 1050–56. http://dx.doi.org/10.1016/j.arth.2011.05.007.

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16

Bolland, Benjamin J. R. F., Janos M. Kanczler, Patrick J. Ginty, et al. "The application of human bone marrow stromal cells and poly(dl-lactic acid) as a biological bone graft extender in impaction bone grafting." Biomaterials 29, no. 22 (2008): 3221–27. http://dx.doi.org/10.1016/j.biomaterials.2008.04.017.

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17

Kaiser, Michael G., Michael W. Groff, William C. Watters, et al. "Guideline update for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 16: Bone graft extenders and substitutes as an adjunct for lumbar fusion." Journal of Neurosurgery: Spine 21, no. 1 (2014): 106–32. http://dx.doi.org/10.3171/2014.4.spine14325.

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In an attempt to enhance the potential to achieve a solid arthrodesis and avoid the morbidity of harvesting autologous iliac crest bone (AICB) for a lumbar fusion, numerous alternatives have been investigated. The use of these fusion adjuncts has become routine despite a lack of convincing evidence demonstrating a benefit to justify added costs or potential harm. Potential alternatives to AICB include locally harvested autograft, calcium-phosphate salts, demineralized bone matrix (DBM), and the family of bone morphogenetic proteins (BMPs). In particular, no option has created greater controver

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18

Belluomo, Ruggero, Inazio Arriola-Alvarez, Nathan W. Kucko, et al. "Physico-Chemical Characteristics and Posterolateral Fusion Performance of Biphasic Calcium Phosphate with Submicron Needle-Shaped Surface Topography Combined with a Novel Polymer Binder." Materials 15, no. 4 (2022): 1346. http://dx.doi.org/10.3390/ma15041346.

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A biphasic calcium phosphate with submicron needle-shaped surface topography combined with a novel polyethylene glycol/polylactic acid triblock copolymer binder (BCP-EP) was investigated in this study. This study aims to evaluate the composition, degradation mechanism and bioactivity of BCP-EP in vitro, and its in vivo performance as an autograft bone graft (ABG) extender in a rabbit Posterolateral Fusion (PLF) model. The characterization of BCP-EP and its in vitro degradation products showed that the binder hydrolyses rapidly into lactic acid, lactide oligomers and unaltered PEG (polyethylene

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19

Eder, C., J. Meissner, W. Bretschneider, S. Schildböck та M. Ogon. "Analysis of a β-TCP bone graft extender explanted during revision surgery after 28 months in vivo". European Spine Journal 23, S2 (2013): 157–60. http://dx.doi.org/10.1007/s00586-013-2802-9.

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20

Hile, David D., Stephen T. Sonis, Stephen A. Doherty, et al. "Dimensional Stability of the Alveolar Ridge After Implantation of a Bioabsorbable Bone Graft Substitute: A Radiographic and Histomorphometric Study in Rats." Journal of Oral Implantology 31, no. 2 (2005): 68–76. http://dx.doi.org/10.1563/0-727.1.

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Abstract This study evaluated reconstruction of the alveolar ridge after molar extraction in rats with bioabsorbable bone repair scaffolds. The material was prepared from the unsaturated polyester poly(propylene glycol-co-fumaric acid) (PPF), which may be cured in situ to form a porous scaffold. The intention is to use this material either as a stand-alone bone graft substitute or as an extender to autograft harvested from mandibular reconstruction sites. The bioactivity of the graft substitute was investigated in a rat residual ridge resorption model. PPF bone repair material was injected int

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21

Lee, Jae Hyup, Bong-Soon Chang, Ul-Oh Jeung, Kun-Woo Park, Min-Seok Kim, and Choon-Ki Lee. "The First Clinical Trial of Beta-Calcium Pyrophosphate as a Novel Bone Graft Extender in Instrumented Posterolateral Lumbar Fusion." Clinics in Orthopedic Surgery 3, no. 3 (2011): 238. http://dx.doi.org/10.4055/cios.2011.3.3.238.

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22

van Haaren, E. H., T. H. Smit, K. Phipps, et al. "Tricalcium-Phosphate/Hydroxyapatite Bone Graft Extender for Use in Impaction Grafting Revision Surgery – an In Vitro Study in Human Femora." Key Engineering Materials 254-256 (December 2003): 667–70. http://dx.doi.org/10.4028/www.scientific.net/kem.254-256.667.

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23

Lee, Jae Hyup, Chang-Ju Hwang, Byung-Wook Song, Ki-Hyung Koo, Bong-Soon Chang, and Choon-Ki Lee. "A prospective consecutive study of instrumented posterolateral lumbar fusion using synthetic hydroxyapatite (Bongros®-HA) as a bone graft extender." Journal of Biomedical Materials Research Part A 90A, no. 3 (2009): 804–10. http://dx.doi.org/10.1002/jbm.a.32113.

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24

Hile, David D., Frank Kandziora, Kai-Uwe Lewandrowski, Stephen A. Doherty, Michael P. Kowaleski, and Debra J. Trantolo. "A poly(propylene glycol-co-fumaric acid) based bone graft extender for lumbar spinal fusion: in vivo assessment in a rabbit model." European Spine Journal 15, no. 6 (2005): 936–43. http://dx.doi.org/10.1007/s00586-005-1001-8.

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25

Tayton, Edward, Sherif Fahmy, Matthew Purcell, et al. "An analysis of polymer type and chain length for use as a biological composite graft extender in impaction bone grafting: A mechanical and biocompatibility study." Journal of Biomedical Materials Research Part A 100A, no. 12 (2012): 3211–19. http://dx.doi.org/10.1002/jbm.a.34264.

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26

Arts, J. J. C., B. W. Schreurs, P. Buma, and N. Verdonschot. "Cemented Cup Stability during Lever-Out Testing after Acetabular Bone Impaction Grafting with Bone Graft Substitutes Mixes Containing Morselized Cancellous Bone and Tricalcium Phosphate-Hydroxyapatite Granules." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 219, no. 4 (2005): 257–63. http://dx.doi.org/10.1243/095441105x34266.

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Bone defects after failed total hip arthroplasty can be reconstructed with impacted morselized bone grafts and a cemented cup. In the near future the amount of bone grafts available for surgical purposes will be insufficient. Ceramic calcium phosphates [tricalcium phosphate (TCP) and hydroxyapatite (HA)] have been widely considered as potential bone graft substitutes or bone graft extenders. In the past, mechanical experiments have been performed to determine implant stability of bone grafts and ceramic TCP-HA granules mixes under a compressive load. However, in-vivo migration studies suggest

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27

Lee, Yu-Po, and Hossein Ghofrani. "Bone Graft Substitutes and Extenders." Contemporary Spine Surgery 10, no. 4 (2009): 1–8. http://dx.doi.org/10.1097/01.css.0000347728.92989.c8.

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28

Borgohain, Bhaskar, Kashif A. Ahmed, and Tashi G. Khonglah. "Endoscopy assisted extended curettage in a rare case of aneurysmal bone cyst involving the 2nd metatarsal of a child." International Journal of Research in Orthopaedics 6, no. 3 (2020): 638. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20201738.

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<p>Aneurysmal bone cysts account for only 1% of all bone tumours and of these only a handful of reported cases occur in the foot. They can mimic other bone tumours on imaging studies, thus making histological diagnosis mandatory. Aneurysmal bone cyst of a metatarsal is very rare especially in children and only few cases have been reported in the literature. We report the novel management option for a rare case of an Aneurysmal bone cyst localized to the second metatarsal in a 5 years old boy who presented with limping, local pain, and minimal swelling in his left foot. Tissue diagnosis w

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29

Boller, Lauren A., Madison A. P. McGough, Stefanie M. Shiels, Craig L. Duvall, Joseph C. Wenke, and Scott A. Guelcher. "Settable Polymeric Autograft Extenders in a Rabbit Radius Model of Bone Formation." Materials 14, no. 14 (2021): 3960. http://dx.doi.org/10.3390/ma14143960.

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Autograft (AG) is the gold standard for bone grafts, but limited quantities and patient morbidity are associated with its use. AG extenders have been proposed to minimize the volume of AG while maintaining the osteoinductive properties of the implant. In this study, poly(ester urethane) (PEUR) and poly(thioketal urethane) (PTKUR) AG extenders were implanted in a 20-mm rabbit radius defect model to evaluate new bone formation and graft remodeling. Outcomes including µCT and histomorphometry were measured at 12 weeks and compared to an AG (no polymer) control. AG control examples exhibited new b

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30

Bernatskiy, Baruch S., and Algirdas Puišys. "A Novel Approach for Implant Rehabilitation Combined with Immediate Bone and Soft-Tissue Augmentation in a Compromised Socket—A B2S Approach: Case Report with a 2-Year Follow-Up." Case Reports in Dentistry 2023 (March 28, 2023): 1–16. http://dx.doi.org/10.1155/2023/1376588.

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In this case report, we aimed to describe a novel approach for aesthetic rehabilitation of the anterior maxilla that combined immediate implant installation with the “Bone2Soft Tissue Reconstruction” (B2S technique), which involves the use of a triple graft harvested from the maxillary tuberosity. The regeneration potential of a tuberosity graft appeared to surpass that of corticocancellous bone grafts harvested from other intraoral donor sites and allowed for quicker regeneration of both bone and soft tissue. The B2S technique extended the indications for immediate implant placement and ridge

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31

Pierannunzii, Luca, and Luigi Zagra. "Bone grafts, bone graft extenders, substitutes and enhancers for acetabular reconstruction in revision total hip arthroplasty." EFORT Open Reviews 1, no. 12 (2016): 431–39. http://dx.doi.org/10.1302/2058-5241.160025.

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32

Burger, Evalina L., and Vikas Patel. "Calcium Phosphates as Bone Graft Extenders." Orthopedics 30, no. 11 (2007): 939–42. http://dx.doi.org/10.3928/01477447-20071101-06.

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33

Varthi, Arya G., and Peter G. Whang. "BONE GRAFT EXTENDERS ARE NOT NEEDED." Journal of Spinal Disorders & Techniques 28, no. 5 (2015): 159–60. http://dx.doi.org/10.1097/01.bsd.0000466800.30532.44.

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34

Hong, Yuhwan, Brent G. Parks, and Stuart D. Miller. "Biomechanical Analysis of Tibial Strength After Harvest of Unicortical Tibial Grafts from Two Different Sites." Foot & Ankle International 27, no. 3 (2006): 190–95. http://dx.doi.org/10.1177/107110070602700307.

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Background: Use of tibial strut grafts has several potential advantages over other donor sites and would be ideal as a harvest site for bone grafts if there are minimal or no resulting risks to tibial stability. Methods: Ten matched-pair cadaver tibiae were randomized to have a 1.5 × 4.0 cm cortical graft harvested from the tibial crest or 1 cm posterior to the tibial crest. Both locations were 6 cm distal to the tibial plateau. The grafts were removed using a high-speed oscillating saw, and each end of the tibia was mounted for testing and loaded onto a servohydraulic test frame. The samples

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35

Minetti, Elio, Gianna Dipalma, Andrea Palermo, et al. "Biomolecular Mechanisms and Case Series Study of Socket Preservation with Tooth Grafts." Journal of Clinical Medicine 12, no. 17 (2023): 5611. http://dx.doi.org/10.3390/jcm12175611.

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The purpose of this research was to assess the effectiveness of an innovative medical device capable of extracting tooth graft materials directly from the patient’s own teeth. Twenty consecutive tooth grafting procedures were conducted, with an average follow-up period of 18 months. Methods: Twenty patients requiring tooth extraction underwent socket preservation utilizing the extracted tooth as the grafting material. Results: After a 4-month healing period, the defects were significantly filled with newly formed hard tissue. Subsequently, bone biopsies were performed during dental implant pla

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36

Barrack, Robert L. "Bone Graft Extenders, Substitutes, and Osteogenic Proteins." Journal of Arthroplasty 20 (June 2005): 94–97. http://dx.doi.org/10.1016/j.arth.2005.03.025.

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37

De Fazio, S., W. C. Hartner, A. P. Monaco, and J. J. Gozzo. "Mouse skin graft prolongation with donor strain bone marrow and anti-lymphocyte serum: surface markers of the active bone marrow cells." Journal of Immunology 135, no. 5 (1985): 3034–38. http://dx.doi.org/10.4049/jimmunol.135.5.3034.

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Abstract The survival of C3H/HeJ skin grafts on B6AF1 mice treated with anti-lymphocyte serum (ALS) can be significantly prolonged by the injection of the host with C3H/HeJ bone marrow. Although the prolongation is apparently due at least in part to the ultimate presence in the host of specific suppressor cells of donor origin, little is known about the nature of the cells in the marrow inoculum that are responsible for this effect. The present investigation was undertaken to characterize surface markers of the active bone marrow cells. Marker-positive populations were either depleted and enri

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38

El Danaf, Ahmed A., Hatem H. Al-Ahmady, Heba A. Eldanaf, et al. "Alveolar Oral Layer Repair by Periosteal Grafts versus Maxillary Flaps and Gingivoperiosteoplasty: Techniques and Follow-up to Adolescence." Plastic and Reconstructive Surgery - Global Open 12, no. 2 (2024): e5633. http://dx.doi.org/10.1097/gox.0000000000005633.

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Background: Alveolar periosteoplasty during primary repair of cleft lip is still a topic of debate due to the fear exacerbating maxillary retrusion. The authors present their experience with early closure of alveolar clefts. The study aims to analyze gingivoperiosteoplasty (GPP) by comparing the use of locoregional flaps versus distant grafts for reconstruction of the lower layer of the primary palate cleft. Methods: Seventeen infants underwent 22 alveolar cleft repairs. After nasal floor repair by nasal mucoperiosteum, the oral layer was repaired by maxillary or gingival periosteal flaps in s

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39

Ryu, Ji-In, Byoung-Eun Yang, Sang-Min Yi, et al. "Bone Regeneration of a 3D-Printed Alloplastic and Particulate Xenogenic Graft with rhBMP-2." International Journal of Molecular Sciences 22, no. 22 (2021): 12518. http://dx.doi.org/10.3390/ijms222212518.

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This study aimed to evaluate the bone regeneration capacity of a customized alloplastic material and xenograft with recombinant human bone morphogenetic protein-2 (rhBMP-2). We prepared hydroxyapatite (HA)/tricalcium phosphate (TCP) pure ceramic bone blocks made using a 3D printing system and added rhBMP-2 to both materials. In eight beagle dogs, a total of 32 defects were created on the lower jaws. The defective sites of the negative control group were left untreated (N group; 8 defects), and those in the positive control group were filled with particle-type Bio-Oss (P group; 12 defects). The

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40

Alsaleh, Khalid A. M., Caroline A. Tougas, Darren M. Roffey, and Eugene K. Wai. "Osteoconductive Bone Graft Extenders in Posterolateral Thoracolumbar Spinal Fusion." Spine 37, no. 16 (2012): E993—E1000. http://dx.doi.org/10.1097/brs.0b013e3182518859.

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41

Nickoli, Michael S., and Wellington K. Hsu. "Ceramic-Based Bone Grafts as a Bone Grafts Extender for Lumbar Spine Arthrodesis: A Systematic Review." Global Spine Journal 4, no. 3 (2014): 211–16. http://dx.doi.org/10.1055/s-0034-1378141.

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42

Manso, José Eduardo Ferreira, Carlos Fernando de Almeida Barros Mourão, Flávio Alexandre Lima Pinheiro, Manoel Luiz Ferreira, Paulo César Silva, and Alberto Schanaider. "Molars extraction for bone graft study in rabbits." Acta Cirurgica Brasileira 26, suppl 2 (2011): 66–69. http://dx.doi.org/10.1590/s0102-86502011000800012.

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PURPOSE: The aim of this study was to describe an experimental surgical technique to be used in the evaluation of bone grafts in rabbits. METHODS: The operative technique was performed in jaws, with external approach from the labial commissure to the last molar tooth. An incision about 1cm extended forward to the alveolar ridge, followed by a exposing the cervical region of the alveolar bone and dental elements was done. Thus, after extraction of first molar with forceps, the tooth socket left was filled with hydroxyapatite. The bone gain was analyzed by histopathological studies. RESULTS: The

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43

Felice, Pietro, Giuseppe Lizio, Carlo Barausse, et al. "Reverse Guided Bone Regeneration (R-GBR) Digital Workflow for Atrophic Jaws Rehabilitation." Applied Sciences 12, no. 19 (2022): 9947. http://dx.doi.org/10.3390/app12199947.

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Background: Treating extended alveolar defects is challenging for their irregular shape and lack of hard and soft tissues. Virtual planned guided bone regeneration (GBR) with customized meshes aims to optimize the treatment by reducing the risk of dehiscence. The mucosa characteristics are crucial in preserving the bone graft covering and vitality. Methods: Two three-dimensional and extended defects, a mandibular posterior and anterior maxillary atrophy were reconstructed with a particulate graft and a digitally customized scaffold. The workflow entailed merging the pre-operatory clinical rela

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44

Champlin, RE, MM Horowitz, DW van Bekkum, et al. "Graft failure following bone marrow transplantation for severe aplastic anemia: risk factors and treatment results." Blood 73, no. 2 (1989): 606–13. http://dx.doi.org/10.1182/blood.v73.2.606.bloodjournal732606.

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Graft failure was analyzed in 625 patients receiving allogeneic bone marrow transplants from HLA-identical sibling donors as treatment for severe aplastic anemia. Sixty-eight (11%) had no or only transient engraftment. Second bone marrow transplants were successful in achieving extended survival in 16 of 27 patients with transient initial engraftment but in none of ten patients with no sign of engraftment after the first transplant. The major factors associated with a reduced risk of graft failure were use of radiation for pretransplant immunosuppression and use of cyclosporine rather than met

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Yang, Ii-Hyung, Young-Ii Chang, Tae-Woo Kim, et al. "Effects of Cleft Type, Facemask Anchorage Method, and Alveolar Bone Graft on Maxillary Protraction: A Three-Dimensional Finite Element Analysis." Cleft Palate-Craniofacial Journal 49, no. 2 (2012): 221–29. http://dx.doi.org/10.1597/10-265.

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Objective To investigate biomechanical effects of cleft type (unilateral/bilateral cleft lip and palate), facemask anchorage method (tooth-borne and miniplate anchorage), and alveolar bone graft on maxillary protraction. Design Three-dimensional finite element analysis with application of orthopedic force (30° downward and forward to the occlusal plane, 500 g per side). Model Computed tomography data from a 13.5-year-old girl with maxillary hypoplasia. Intervention Eight three-dimensional finite element models were fabricated according to cleft type, facemask anchorage method, and alveolar bon

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Champlin, RE, MM Horowitz, DW van Bekkum, et al. "Graft failure following bone marrow transplantation for severe aplastic anemia: risk factors and treatment results." Blood 73, no. 2 (1989): 606–13. http://dx.doi.org/10.1182/blood.v73.2.606.606.

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Abstract Graft failure was analyzed in 625 patients receiving allogeneic bone marrow transplants from HLA-identical sibling donors as treatment for severe aplastic anemia. Sixty-eight (11%) had no or only transient engraftment. Second bone marrow transplants were successful in achieving extended survival in 16 of 27 patients with transient initial engraftment but in none of ten patients with no sign of engraftment after the first transplant. The major factors associated with a reduced risk of graft failure were use of radiation for pretransplant immunosuppression and use of cyclosporine rather

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Abdelaal, Ahmed H. K., Ahmed S. S. Sleem, and Emmanouil Liodakis. "Early results of the combined grafting–cementation technique for the treatment of giant cell tumors with a large subchondral bone defect: a case series." Egyptian Orthopaedic Journal 59, no. 2 (2024): 154–61. http://dx.doi.org/10.4103/eoj.eoj_6_24.

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Background Giant cell tumor (GCT) is a rare, locally aggressive bone tumor. It typically affects young adults close to the joints, mainly the knee joint. The high recurrence rate, along with erosion of the subchondral bone complicates the surgical plan. Current treatment standards involve extended curettage followed by space-filling by cement or graft. We present a detailed technique using a combined technique using both bone graft and cement for reconstructing GCT-related subchondral damage. Patients and methods Eighteen patients underwent surgery from January 2018 to December 2021. The surge

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Aro, Hannu T., Ville-Valtteri Välimäki, Niko Strandberg, et al. "Bioactive glass granules versus standard autologous and allogeneic bone grafts: a randomized trial of 49 adult bone tumor patients with a 10-year follow-up." Acta Orthopaedica 93 (June 1, 2022): 519–27. http://dx.doi.org/10.2340/17453674.2022.2808.

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Background and purpose: As a synthetic bone void filler, bioactive glasses (BGs) may enhance angiogenesis and osteogenesis. In this randomized trial, we compared the clinical efficacy of BG granules and standard bone grafts in patients undergoing surgery for benign bone tumors.Patients and methods: 49 recruited patients were randomized to receive BG granules or undergo conventional bone grafting to fill defects following tumor removal. As the standard of care, small-sized defects were filled with autologous graft, and large-sized defects were filled with allogeneic graft. The primary endpoint

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Omori, Hiroyuki, Daniele Botticelli, Erick Ricardo Silva, et al. "Analysis of Implant Osseointegration, Bone Repair, and Sinus Mucosa Integrity Using Bio-Oss® and Hyaluronic Acid-Polynucleotide Gel (Regenfast®) in Maxillary Sinus Augmentation in Rabbits." Dentistry Journal 13, no. 7 (2025): 293. https://doi.org/10.3390/dj13070293.

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Background: The combination of polynucleotides and hyaluronic acid with bovine bone grafts in maxillary sinus lift procedures appears to be a promising strategy to enhance bone regeneration. This study aimed to analyze implant osseointegration, bone repair and sinus mucosa integrity using Bio-Oss® and Hyaluronic Acid-Polynucleotide Gel (Regenfast®) in maxillary sinus augmentation in rabbits. Methods: Sinus floor elevation was performed in 12 rabbits, with one implant placed per sinus simultaneously. In the control group, sinuses were grafted with deproteinized bovine bone mineral (Bio-Oss®) al

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Rodrigues, Michael, Bert W. O'Malley, Hinrich Staecker, and Rafael Tamargomd. "Extended pericranial flap and bone graft reconstruction in anterior skull base surgery." Otolaryngology–Head and Neck Surgery 131, no. 1 (2004): 69–76. http://dx.doi.org/10.1016/j.otohns.2004.02.033.

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