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Dissertations / Theses on the topic 'Bone-grafting'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 June 2025

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1

Herbert, Amy Angharad. "Bone grafting : tissue treatment and osseointegration." Thesis, Cardiff University, 2004. http://orca.cf.ac.uk/55547/.

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Bone grafts fill skeletal defects and provide a structure upon which new bone can be deposited. There is no standard method of storing bone prior to grafting, the three main storage regimes being stored fresh frozen at -80°C, gamma irradiated or freeze dried. The initial aim of this project was to determine how osteoblastic cells behaved when exposed to bone treated in the above ways. It was found that sterilisation of bone with gamma irradiation caused cell death in a number of the cells that came into contact with it. Therefore the use of gamma irradiation for grafting is contraindicated, a

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2

Mak, Siu Yan. "Mechanical factors influencing impaction bone grafting." Thesis, University of Bath, 2007. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486839.

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Impaction grafting for bone stock loss in revision total hip arthroI;>lasty has been used for over a decade. This technique typically involves the insertion of a cemented highly polished stem into impacted morsellised allograft bone. The aim is to compensate for the bone stock loss after failed primary hip arthroplasty and to provide a mechanical and biological scaffold for mechanical support and bone remodelling. The primary objective of this study is to quantify and optimise the graft properties so as to provide maximum supportive forces to the stem, and, at' the same time, to minimise the a

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3

Twitty, Anne. "The expression of tissue inhibitor of metalloproteinase during the early stages of bone graft healing." Thesis, Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21804023.

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4

Dattani, Rupen. "Femoral impaction grafting : using bone graft substitutes." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1444261/.

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Background: Femoral impaction allografting to reconstitute bone loss during revision hip surgery has shown excellent results. However, limitations with the use of allografts have warranted research to investigate if bone graft substitutes could be a suitable alternative to replace or augment allograft in impaction grafting.;Aims and Methods: The objectives of this thesis were to assess if: The use of hydroxyapatite (HA) in various combinations with allograft will be biologically effective and functionally stable using a cemented impaction grafting technique in an ovine hemiarthroplasty model.

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5

黃美娟 and May-kuen Alice Wong. "Bone induction of demineralized intramembranous and endochondral bone matrices." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B3197305X.

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6

Wong, May-kuen Alice. "Bone induction of demineralized intramembranous and endochondral bone matrices." View the Table of Contents & Abstract, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21872752.

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7

Thorén, Klas. "Lipid-extracted bone grafts." Lund : Dept. of Orthopedics, University Hospital, Lund University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39676934.html.

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8

Lie, Ken Jie Ronny Ket Phoei. "The healing of composite endochondral bone grafts a qualitative and quantitative analysis /." Hong Kong : Faculty of Dentistry, The University of Hong Kong, 1995. http://sunzi.lib.hku.hk/HKUTO/record/B38628120.

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9

李國培 and Ken Jie Ronny Ket Phoei Lie. "The healing of composite endochondral bone grafts: a qualitative and quantitative analysis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B38628120.

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10

McNamara, Iain Robert. "Characterisation of the mechanical response of morcellised bone graft and bone graft substitutes for impaction grafting." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608923.

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11

Wong, Wing-kit Ricky, and 黃永傑. "The effect of demineralized intramembranous bone matrix on the healingof autogenous bone grafts." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31973061.

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12

Gan, Jade Ho Yue School of Biomedical Engineering UNSW. "Characterisation of bone defect models in immunodeficient animals." Awarded by:University of New South Wales. School of Biomedical Engineering, 2005. http://handle.unsw.edu.au/1959.4/22429.

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Bone defects resulting from non-unions, fractures, significant revision joint replacements, tumour resection and osteolysis present a clinical problem. While autografts are considered the gold standard, ubiquitous use of this reparative technique is limited by graft supply and site morbidity. Recent progresses in tissue engineering using stem cells, bone enhancing molecules and gene therapy have provided more hypotheses for bone defect treatment. In vivo assessment to test these hypotheses requires animal models to mimic human conditions. Immunodeficient or nude animals have the advantage of h

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13

Wong, Wing-kit Ricky. "The effect of demineralized intramembranous bone matrix on the healing of autogenous bone grafts." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/hkuto/record/B31973061.

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14

Gundle, Roger. "Microscopical and biochemical studies of mineralised matrix production by bone-derived cells." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282203.

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15

Muller, Sébastien. "Mechanical and adaptive behaviour of bone in relation to hip replacement : A study of bone remodelling and bone grafting." Doctoral thesis, Norwegian University of Science and Technology, Department of Structural Engineering, 2005. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-2067.

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<p>This thesis, consisting of an introduction and four separate papers, gathers considerations on bone behaviour in relation to total hip replacement. Aspects related to primary hip replacement, principally adaptive bone remodelling, are addressed in Paper I from a clinical point of view and in Paper II from a mechanical point of view. Morsellised bone applied in secondary hip replacement is studied in Paper III, where its recoil is modelled as viscoelastic, while Paper IV questions the validity of a solid model for this material.</p><p>The relationship between preoperative bone stock and rela

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16

Farnsworth, Kelly Dee Jr. "Evaluation of Two Techniques of Cancellous Bone Grafting of Experimental Subchondral Bone Cysts in the Medial Femoral Condyles of Horses." Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/36870.

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Cylindric (10 mm diameter X 15 mm deep) osteochondral defects were created in the medial femoral condyles of 5 horses to mimic clinical cases of subchondral bone cysts after debridement. The defects were created with either a standard square ended drill bit or a compaction drill bit. The compaction drill bit compresses bone laterally and distally creating a dense wall and floor. Twelve-mm sternal cancellous cylinders were compressed to 9.25 mm and inserted into the femoral defects where they were presumed to expand and tighten the fit. The end result was sternal cancellous bone that exactl

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17

Abbah, Sunny Akogwu. "Towards an injectable bone graft substitute evaluation of sodium alginate microcapsules for bone tissue engineering /." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B39329951.

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18

Hui, Hin-ming. "The morbidity of anterior iliac bone harvesting for maxillofacial grafting procedures." Click to view the E-thesis via HKUTO, 1998. http://sunzi.lib.hku.hk/HKUTO/record/B38628211.

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19

Monaghan, Pierre. "Histological analysis of bovine bone grafting using the rat tibia model." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=55515.

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Experimental investigations were carried out concerning the use of bovine bone (Unilab Surgibone) grafted in the tibiae of rats. The first experiment evaluated tissue response of bovine bone as an inlay graft and the second experiment as an onlay graft. Histological and morphometric analyses were performed in order to obtain baseline data on tissue response for future experiments using titanium implants with bovine bone grafts in this model. Light microscopy demonstrated rapid incorporation of the inlay graft by new bone, whereas, the onlay graft was mainly encapsulated by fibrous tissue. Howe

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20

Orellana, Bryan R. "BIOERODIBLE CALCIUM SULFATE BONE GRAFTING SUBSTITUTES WITH TAILORED DRUG DELIVERY CAPABILITIES." UKnowledge, 2014. http://uknowledge.uky.edu/cbme_etds/18.

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Bone regeneration or augmentation is often required prior to or concomitant with implant placement. With the limitations of many existing technologies, a biologically compatible synthetic bone grafting substitute that is osteogenic, bioerodible, and provides spacing-making functionality while acting as a drug delivery vehicle for bioactive molecules could provide an alternative to ‘gold standard’ techniques. In the first part of this work, calcium sulfate (CS) space-making synthetic bone grafts with uniformly embedded poly(β-amino ester) (PBAE) biodegradable hydrogel particles was developed to

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21

許顯名 and Hin-ming Hui. "The morbidity of anterior iliac bone harvesting for maxillofacial grafting procedures." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B38628211.

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22

Patel, Nelesh. "In vivo assessment of hydroxyapatite and substituted apatites for bone grafting." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.615793.

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23

Crout, Richard Morrow. "Timing of alveolar cleft bone grafting in maxillary alveolar cleft defects." Morgantown, W. Va. : [West Virginia University Libraries], 2000. http://etd.wvu.edu/templates/showETD.cfm?recnum=1446.

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24

Matsushita, Naoya, Atsushi Kouyama, and Toshiki Iwase. "COMPLETE BONE REMODELING AFTER CALCAR RECONSTRUCTION WITH METAL WIRE MESH AND IMPACTION BONE GRAFTING: A CASE REPORT." Nagoya University School of Medicine, 2013. http://hdl.handle.net/2237/18479.

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25

Chay, Siew Han. "Vascular endothelial growth pattern during demineralized bone matrix (intramembranous bone origin) induced osteogenesis." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/HKUTO/record/B38628417.

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26

Cvijic, Gojko 1971. "Comparação clinica e radiografica do carregamento protetico precoce entre implantes com superficies fisica e quimicamente modificadas, inseridos em areas enxertadas em maxila." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289075.

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Orientador: Frederico Andrade e Silva<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-13T01:24:11Z (GMT). No. of bitstreams: 1 Cvijic_Gojko_M.pdf: 808997 bytes, checksum: 9dea6418612a9a36ca0683f628728557 (MD5) Previous issue date: 2009<br>Resumo: Varias pesquisas tem mostrado que aumento de energia na superfície e a fabricação do implante na ausência de ar, aumenta a hidrofilia da superfície reduzindo o tempo da osseointegração. O objetivo desse estudo foi a avaliar o tempo de vida útil e o Nível de

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27

Day, Adam George Edward. "The optimisation of tissue regeneration for bone grafts." Thesis, Swansea University, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678386.

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28

Tilley, Simon. "Seeding of Human Bone Marrow Stromal Cells onto Bone Graft Substitutes and Allograft - An Impaction Grafting Model." Thesis, University of Southampton, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494385.

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29

Tuominen, T. (Tapio). "Native bovine bone morphogenetic protein in the healing of segmental long bone defects." Doctoral thesis, University of Oulu, 2001. http://urn.fi/urn:isbn:9514264789.

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Abstract A new animal model was developed to evaluate the effect of bovine native bone morphogenetic protein (BMP) on the healing of segmental, critical-sized bone defects. Laboratory-bred adult beagle dogs were used in the study. A 2 cm corticoperiosteal defect was created using an oscillating saw in mid-ulna, and the defect was treated with bone grafts and implants fixed by an intramedullary Kirschner wire through predrilled holes in the middle of the implant. Plate and screw fixation was also used in some groups. Coral, hydroxyapatite and demineralized xenograft bone were placed in the d

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30

Campbell, David Graham. "Sterilization of HIV infected bone allografts /." Title page, contents and abstract only, 1996. http://web4.library.adelaide.edu.au/theses/09PH/09phc1869.pdf.

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31

Porter, Alexandra Elizabeth. "Ultrastructural comparison of hydroxyapatite and silicon-substituted hydroxyapatite for bone grafting applications." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620067.

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32

謝秀嫻 and Siew Han Chay. "Vascular endothelial growth pattern during demineralized bone matrix (intramembranous bone origin) induced osteogenesis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B38628417.

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33

Abbah, Sunny Akogwu. "Towards an injectable bone graft substitute: evaluation of sodium alginate microcapsules for bone tissueengineering." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B39329951.

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34

周明忠 and Ming-chung Chow. "The healing of endochondral bone grafts in the presence of the demineralized intramembranous bone matrix: :a qualitative andquantitative analysis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B38628429.

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35

Chow, Ming-chung. "The healing of endochondral bone grafts in the presence of the demineralized intramembranous bone matrix :a qualitative and quantitative analysis." Click to view the E-thesis via HKUTO, 1999. http://sunzi.lib.hku.hk/HKUTO/record/B38628429.

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36

Chen, Jinbiao Prince of Wales Clinical School UNSW. "In vitro and in vivo bone formation - assessment and application." Awarded by:University of New South Wales. Prince of Wales Clinical School, 2006. http://handle.unsw.edu.au/1959.4/24922.

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Background: Bone-grafting materials are required in orthopaedic surgery to treat bone defects. Bone formation assessment is required for the development of new strategies and approaches and for quality assurance and quality control of currently available materials. Approaches to the assessment of bone formation are yet to be systematically established, quantified and standardized. Aims: the overall aim of this study was to establish a set of comprehensive quantitative approaches for the assessment of bone formation and to evaluate the role of osteoblastic cells, growth factors, and scaffolds

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37

陸梅 and Mei Lu. "Allogeneic bone grafts mixed with basic fibroblast growth factor: a cellular and molecular study." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B29866340.

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38

Rewinkel, Scott Everett. "The effects of SiO₂, ZnO, and MgO doping on the mechanical and biological properties of beta-tricalcium phosphate bioceramics for bone tissue engineering, in vitro and in vivo analysis." Pullman, Wash. : Washington State University, 2009. http://www.dissertations.wsu.edu/Thesis/Fall2009/s_rewinkel_100909.pdf.

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Thesis (M.S. in mechanical engineering)--Washington State University, December 2009.<br>Title from PDF title page (viewed on Jan. 22, 2010). "School of Mechanical and Materials Engineering." Includes bibliographical references (p. 123-128).

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39

Kingsmill, Virginia Jane. "Bone structure and turnover in the adult human mandible." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.480655.

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40

Grimm, Bernd. "Mechanical properties of morsellised bone graft and synthetic graft extenders for impaction grafting." Thesis, University of Bath, 2003. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760845.

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41

Bolland, Benjamin J. R. F. "Mechanical and biological augmentation of allograft and synthetic graft in impaction bone grafting." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/79021/.

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Aims: This thesis has three main aims: • To investigate the potential role of human bone marrow stromal cells (HBMSC) in Impaction Bone Grafting (IBG). • To investigate the potential role of a synthetic graft, Poly (DL-lactic acid), (PDLLA) as a tissue engineering scaffold and a graft extender in IBG. • To investigate methods to improve graft compaction and reduce fracture risk in IBG. Methods: Part I: The biocompatibility and mechanical properties of HBMSC seeded onto allograft or PDLLA were compared to allograft or PDLLA alone in vitro. Part II: Evidence of biocompatibility, neovascularisati

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42

Jayasekera, Tissa R. "Autogenous Secondary Alveolar Bone Grafting In The Treatment Of Cleft Lip And Palate." Thesis, The University of Sydney, 1989. http://hdl.handle.net/2123/4871.

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43

Salmasi, S. "Development of a hydroxyapatite/POSS-PCU composite film for bone grafting and augmentation." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1563547/.

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The current approach towards treating critical size bone defects, with the aim of repairing or regenerating bone, is the use of bone grafts (autografts or allografts). However, due to various disadvantages associated with the use of autografts and allografts, biomaterials; synthetic ceramic/polymer composites as bone grafts substitutes and guided bone regeneration membranes in particular, have been recognised as effective alternatives to the traditional methods. Polyhedral oligomeric silsesquioxane covalently bonded to poly(carbonate- urea-urethane), (POSS-PCU), a novel co-polymer, has display

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44

Conway, Jordan C. "Highly silicated hydroxyapatite : synthesis, characterisation and evaluation." Thesis, University of Aberdeen, 2017. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=235581.

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45

Tanaka, Kojiro. "A bioactive and bioresorbable porous cubic composite scaffold loaded with bone marrow aspirate: A potential alternative to autogenous bone grafting." Kyoto University, 2010. http://hdl.handle.net/2433/120597.

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46

Tayton, Edward R. "Novel approaches towards the successful implementation of tissue engineering strategies in impaction bone grafting." Thesis, University of Southampton, 2014. https://eprints.soton.ac.uk/375050/.

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47

De, Santis Enzo [UNESP]. "Reparação do tecido ósseo peri-implantar após enxerto ósseo autógeno e heterógeno: estudo experimental histológico em cães." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/103317.

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Made available in DSpace on 2014-06-11T19:32:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-09-05Bitstream added on 2014-06-13T21:04:26Z : No. of bitstreams: 1 desantis_e_dr_araca.pdf: 2787266 bytes, checksum: b11c83dbba262a0641d23d2d0ceb74da (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Objetivo: avaliar a regeneração da crista óssea alveolar e o processo de osseointegração de implantes instalados em sítios enxertados com blocos de osso autógeno e osso bovino mineral (DBBM),associado a membrana de colágeno. Material e método: em 6 cães labradores

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48

Tong, Chi-kit Antonio, and 唐志傑. "Meniscectomy and autogenous graft reconstruction of the rhesus monkey temporomandibular joint articular disc." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B29821691.

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49

Tong, Chi-kit Antonio. "Meniscectomy and autogenous graft reconstruction of the rhesus monkey temporomandibular joint articular disc /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20377897.

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50

Dunlop, D. G. "Mechanical and biological aspects of impaction bone grafting in revision hip surgery and the use of a new synthetic bone graft." Thesis, University of Edinburgh, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.649798.

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This thesis examines, in three phases, the biological and mechanical properties of impacted morcellised bone graft and the use of synthetic additives. Phase I. The mechanical strengths of different mixtures of bone graft were found to follow sound Engineering principles. The distribution of particle sizes from different bone mills determines the mechanical strength of graft from that mill. Theoretical increases in strength by improving particle size distribution were confirmed by mechanical tests Washing the graft or the addition of synthetic additives (Controlled Release Glass - Corglaes<sup>

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