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1

Sharma, Anamika, and Himani Sharma. "Bone Morphogenetic Proteins: An Overview." Annals of Applied Bio-Sciences 4, no. 2 (2017): R35—R37. http://dx.doi.org/10.21276/aabs.1336.

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2

Einhorn, Thomas A. "BONE MORPHOGENETIC PROTEINS." Journal of Bone & Joint Surgery 79, no. 2 (1997): 318. http://dx.doi.org/10.2106/00004623-199702000-00024.

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3

Einhorn, Thomas A. "Bone Morphogenetic Proteins." Journal of Bone and Joint Surgery (American Volume) 79, no. 2 (1997): 319. http://dx.doi.org/10.2106/00004623-199702000-00026.

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4

TERMAAT, M. F., F. C. DEN BOER, F. C. BAKKER, P. PATKA, and H. J. TH M. HAARMAN. "BONE MORPHOGENETIC PROTEINS." Journal of Bone and Joint Surgery-American Volume 87, no. 6 (2005): 1367–78. http://dx.doi.org/10.2106/00004623-200506000-00027.

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5

Katagiri, Takenobu, and Tetsuro Watabe. "Bone Morphogenetic Proteins." Cold Spring Harbor Perspectives in Biology 8, no. 6 (2016): a021899. http://dx.doi.org/10.1101/cshperspect.a021899.

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6

&NA;. "Bone Morphogenetic Proteins." Back Letter 25, no. 11 (2010): 125–26. http://dx.doi.org/10.1097/01.back.0000390600.95274.20.

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7

Chen, Di, Ming Zhao, and Gregory R. Mundy. "Bone Morphogenetic Proteins." Growth Factors 22, no. 4 (2004): 233–41. http://dx.doi.org/10.1080/08977190412331279890.

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8

Carreira, A. C., F. H. Lojudice, E. Halcsik, R. D. Navarro, M. C. Sogayar, and J. M. Granjeiro. "Bone Morphogenetic Proteins." Journal of Dental Research 93, no. 4 (2014): 335–45. http://dx.doi.org/10.1177/0022034513518561.

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9

Wozney, John M. "Bone Morphogenetic Proteins." Progress in Growth Factor Research 1, no. 4 (1989): 267–80. http://dx.doi.org/10.1016/0955-2235(89)90015-x.

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10

Azari, Kodi, John S. Doctor, Bruce A. Doll, and Jeffrey O. Hollinger. "Bone morphogenetic proteins." Oral and Maxillofacial Surgery Clinics of North America 14, no. 1 (2002): 1–14. http://dx.doi.org/10.1016/s1042-3699(02)00011-0.

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11

Bibbo, Christopher, Jonas Nelson, David Ehrlich, and Brian Rougeux. "Bone Morphogenetic Proteins." Clinics in Podiatric Medicine and Surgery 32, no. 1 (2015): 35–43. http://dx.doi.org/10.1016/j.cpm.2014.09.005.

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12

Towler, Dwight A. "Bone morphogenetic proteins." Blood 114, no. 10 (2009): 2012–13. http://dx.doi.org/10.1182/blood-2009-06-228544.

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Abstract BMP2 and BMP4 play crucial inductive roles during development. In this issue of Blood, Shao et al demonstrate that an intricate network of paracrine BMP2/4 signals also regulates angiogenesis—and will very likely interact with endocrine BMP cues during wound repair.1
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13

Reddi, Hari. "Bone Morphogenetic Proteins." Advances in Dental Research 9, no. 3_suppl (1995): 13. http://dx.doi.org/10.1177/0895937495009003s0401.

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14

Aihanuwa, Uwagie-Ero, Kene Chukwujekwu, and Chilaka Chukwuemeke. "Bone Morphogenetic Proteins an Update and Review." Tropical Journal of Natural Product Reseach 1, no. 1 (2017): 1–11. http://dx.doi.org/10.26538/tjnpr/v1i1.2.

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15

Reddi, A. H. "BMPs: From bone morphogenetic proteins to body morphogenetic proteins." Cytokine & Growth Factor Reviews 16, no. 3 (2005): 249–50. http://dx.doi.org/10.1016/j.cytogfr.2005.04.003.

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16

Ripamonti, Ugo, and Nicolaas Duneas. "Tissue Morphogenesis and Regeneration by Bone Morphogenetic Proteins." Plastic and Reconstructive Surgery 101, no. 1 (1998): 227–39. http://dx.doi.org/10.1097/00006534-199801000-00040.

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17

Malysheva, Kh V., I. M. Spasyuk, O. K. Pavlenko, R. S. Stoika, and O. G. Korchynsky. "Generation of optimized preparations of bone morphogenetic proteins for bone regeneration." Ukrainian Biochemical Journal 88, no. 6 (2016): 87–97. http://dx.doi.org/10.15407/ubj88.06.087.

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18

Yoshikawa, Hideki, Takanobu Nakase, Akira Myoui, and Takafumi Ueda. "Bone morphogenetic proteins in bone tumors." Journal of Orthopaedic Science 9, no. 3 (2004): 334–40. http://dx.doi.org/10.1007/s00776-004-0764-9.

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19

Mussano, Federico, Giovannino Ciccone, Manuela Ceccarelli, Ileana Baldi, and Francesco Bassi. "Bone Morphogenetic Proteins and Bone Defects." Spine 32, no. 7 (2007): 824–30. http://dx.doi.org/10.1097/01.brs.0000259227.51180.ca.

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20

Rengachary, Setti S. "Bone morphogenetic proteins: basic concepts." Neurosurgical Focus 13, no. 6 (2002): 1–6. http://dx.doi.org/10.3171/foc.2002.13.6.3.

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The cellular and molecular events governing bone formation in the embryo, healing of a fractured bone, and induced bone fusion follow a similar pattern. Discovery, purification, and recombinant synthesis of bone morphogenetic proteins (BMPs) constiute a major milestone in the understanding of bone physiology. In this review the author discusses the mechanism of action, clinical applications, dosage, and optimum carriers for BMPs. The roles played by other growth factors are also discussed.
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21

Mukhametov, Ural F., Sergey V. Lyulin, Dmitry Yu Borzunov, and Ilgiz F. Gareev. "Methods for assessing the effectiveness of using bone morphogenetic proteins in spondylodesis." HERALD of North-Western State Medical University named after I.I. Mechnikov 14, no. 3 (2022): 13–25. http://dx.doi.org/10.17816/mechnikov106089.

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BACKGROUND: Today, growth factors, in particular bone morphogenetic proteins in the composition of osteoplastic materials, are widely used to accelerate bone tissue regeneration after injuries or diseases of the musculoskeletal system. There are various methods for evaluating the effectiveness of using these proteins, in particular, the methods for medical imaging and determining specific markers. Bone loss often occurs after trauma or injury, including surgery. Rapid impairment of bone formation and increased bone resorption, as reflected by biochemical markers of bone metabolism, may cause t
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22

Rao, SubramaniamM, GauriM Ugale, and ShivarajB Warad. "Bone morphogenetic proteins: Periodontal regeneration." North American Journal of Medical Sciences 5, no. 3 (2013): 161. http://dx.doi.org/10.4103/1947-2714.109175.

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23

Hwang, Chang Ju, Alexander R. Vaccaro, James P. Lawrence, et al. "Immunogenicity of bone morphogenetic proteins." Journal of Neurosurgery: Spine 10, no. 5 (2009): 443–51. http://dx.doi.org/10.3171/2009.1.spine08473.

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Object The object of this paper is to review the immunogenicity of bone morphogenetic proteins (BMPs) and to compare the results of the immunogenicity characterization and clinical consequences between recombinant human (rh)BMP-2 and recombinant human osteogenic protein-1 (rhOP-1/BMP-7). Methods The immunogenicity of therapeutic proteins and its clinical effects were reviewed. The characteristics of BMPs were also described in terms of immunogenicity. The methods and results of antibody detection in various clinical trials of rhBMP-2 and rhOP-1 were compared, including the most recent studies
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24

Sharma, Himani, and Anamika Sharma. "Bone morphogenetic proteins: Revivifying periodontium." Indian Journal of Multidisciplinary Dentistry 9, no. 1 (2019): 58. http://dx.doi.org/10.4103/ijmd.ijmd_21_19.

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25

Thawani, Jayesh P., Anthony C. Wang, Khoi D. Than, Chia-Ying Lin, Frank La Marca, and Paul Park. "Bone Morphogenetic Proteins and Cancer." Neurosurgery 66, no. 2 (2010): 233–46. http://dx.doi.org/10.1227/01.neu.0000363722.42097.c2.

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26

Wozney, John M. "Overview of Bone Morphogenetic Proteins." Spine 27, Supplement (2002): S2—S8. http://dx.doi.org/10.1097/00007632-200208151-00002.

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27

Helm, Greg, D. Greg Anderson, Gunnar B. J. Andersson, et al. "Summary Statement: Bone Morphogenetic Proteins." Spine 27, Supplement (2002): S9. http://dx.doi.org/10.1097/00007632-200208151-00003.

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28

Huylebroeck, Danny. "Bone morphogenetic proteins go endothelial." Blood 109, no. 5 (2007): 1794–95. http://dx.doi.org/10.1182/blood-2006-12-061994.

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29

Hogan, Brigid LM. "Bone morphogenetic proteins in development." Current Opinion in Genetics & Development 6, no. 4 (1996): 432–38. http://dx.doi.org/10.1016/s0959-437x(96)80064-5.

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30

Prakash, C. A., J. Parthiban, R. Balakrishnan, B. Anandh, and B. Lokesh. "Bone Morphogenetic Proteins-An Update." Biomedical and Pharmacology Journal 8, october Spl Edition (2015): 329–33. http://dx.doi.org/10.13005/bpj/699.

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31

Bramlage, C. P., T. Häupl, C. Kaps, P. Bramlage, G. A. Müller, and F. Strutz. "Bone Morphogenetic Proteins im Skelettsystem—." Zeitschrift für Rheumatologie 64, no. 6 (2005): 416–22. http://dx.doi.org/10.1007/s00393-005-0665-0.

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32

EINHORN, THOMAS. "Role of Bone Morphogenetic Proteins." Rheumatology News 4, no. 2 (2005): 10. https://doi.org/10.1016/s1541-9800(05)70551-2.

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33

Ripamonti, Ugo, and A. Hari Reddi. "Tissue Engineering, Morphogenesis, and Regeneration of the Periodontal Tissues By Bone Morphogenetic Proteins." Critical Reviews in Oral Biology & Medicine 8, no. 2 (1997): 154–63. http://dx.doi.org/10.1177/10454411970080020401.

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Tissue engineering is the emerging field of science developing techniques for fabrication of new tissues for replacement based on principles of cell and developmental biology and biomaterials. Morphogenesis is the cascade of pattern formation and the attainment of form of the various organs and the organism as a whole. The periodontium consists of the periodontal ligament, cementum, and alveolar bone. Bone has considerable potential for regeneration and therefore is a prototypic model for tissue engineering. The three main ingredients for tissue engineering are regulatory signals, responding s
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34

Wordinger, Robert J., and Abbot F. Clark. "Bone Morphogenetic Proteins and Their Receptors in the Eye." Experimental Biology and Medicine 232, no. 8 (2007): 979–92. http://dx.doi.org/10.3181/0510-mr-345.

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The human genome encodes at least 42 different members of the transforming growth factor-β superfamily of growth factors. Bone morphogenetic proteins (BMPs) are the largest subfamily of proteins within the transforming growth factor-β superfamily and are involved in numerous cellular functions including development, morphogenesis, cell proliferation, apoptosis, and extracellular matrix synthesis. This article first reviews BMPs and BMP receptors, BMP signaling pathways, and mechanisms controlling BMP signaling. Second, we review BMP and BMP receptor expression during embryonic ocular developme
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35

Walker, David H., and Neill M. Wright. "Bone morphogenetic proteins and spinal fusion." Neurosurgical Focus 13, no. 6 (2002): 1–13. http://dx.doi.org/10.3171/foc.2002.13.6.4.

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Bone morphogenetic proteins (BMPs) have increasingly become a focus of research in the laboratory, with animal models, and in human clinical trials for the treatment of spinal disorders. Basic science research has elucidated the putative mechanism of action of BMPs, and the efficacy of BMPs in inducing bone formation has been evaluated in multiple animal models of anterior and posterior spinal fusion. Not only has BMP been shown to improve the quality and amount of bone formation when used as a supplement to autograft, it has also been shown to promote superior fusion in the absence of autogra
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36

Elmasry, Khaled, Samar Habib, Mohamed Moustafa, and Mohamed Al-Shabrawey. "Bone Morphogenetic Proteins and Diabetic Retinopathy." Biomolecules 11, no. 4 (2021): 593. http://dx.doi.org/10.3390/biom11040593.

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Bone morphogenetic proteins (BMPs) play an important role in bone formation and repair. Recent studies underscored their essential role in the normal development of several organs and vascular homeostasis in health and diseases. Elevated levels of BMPs have been linked to the development of cardiovascular complications of diabetes mellitus. However, their particular role in the pathogenesis of microvascular dysfunction associated with diabetic retinopathy (DR) is still under-investigated. Accumulated evidence from our and others’ studies suggests the involvement of BMP signaling in retinal inf
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37

Jain, AenaPundir, Siddharth Pundir, and Anamika Sharma. "Bone morphogenetic proteins: The anomalous molecules." Journal of Indian Society of Periodontology 17, no. 5 (2013): 583. http://dx.doi.org/10.4103/0972-124x.119275.

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38

Ducy, Patricia, and Gerard Karsenty. "The family of bone morphogenetic proteins." Kidney International 57, no. 6 (2000): 2207–14. http://dx.doi.org/10.1046/j.1523-1755.2000.00081.x.

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39

Singh, Kern, Dustin H. Massel, Benjamin C. Mayo, Daniel D. Bohl, William W. Long, and Krishna D. Modi. "Bone Morphogenetic Proteins in Lumbar Arthrodesis." Journal of Bone and Joint Surgery 98, no. 13 (2016): e57. http://dx.doi.org/10.2106/jbjs.16.00316.

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40

Malham, Gregory M., Graham G. Giles, Roger L. Milne, Carl M. Blecher, and Graeme A. Brazenor. "Bone Morphogenetic Proteins in Spinal Surgery." Spine 40, no. 22 (2015): 1737–42. http://dx.doi.org/10.1097/brs.0000000000001184.

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41

Azari, Kodi, Bruce A. Doll, Charles Sfeir, Ying Mu, and Jeffrey O. Hollinger. "Therapeutic potential of bone morphogenetic proteins." Expert Opinion on Investigational Drugs 10, no. 9 (2001): 1677–86. http://dx.doi.org/10.1517/13543784.10.9.1677.

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42

Felin, Jenny E., Jaime L. Mayo, Trina J. Loos, et al. "Nuclear variants of bone morphogenetic proteins." BMC Cell Biology 11, no. 1 (2010): 20. http://dx.doi.org/10.1186/1471-2121-11-20.

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43

Nauth, Aaron, Peter V. Giannoudis, Thomas A. Einhorn, et al. "Growth Factors: Beyond Bone Morphogenetic Proteins." Journal of Orthopaedic Trauma 24, no. 9 (2010): 543–46. http://dx.doi.org/10.1097/bot.0b013e3181ec4833.

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44

Gautschi, Oliver P., Sönke P. Frey, and René Zellweger. "BONE MORPHOGENETIC PROTEINS IN CLINICAL APPLICATIONS." ANZ Journal of Surgery 77, no. 8 (2007): 626–31. http://dx.doi.org/10.1111/j.1445-2197.2007.04175.x.

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45

Aspenberg, P., and C. Forslund. "Bone morphogenetic proteins and tendon repair." Scandinavian Journal of Medicine & Science in Sports 10, no. 6 (2000): 372–75. http://dx.doi.org/10.1034/j.1600-0838.2000.010006372.x.

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46

Carlisle, Elliot, and Jeffrey S. Fischgrund. "Bone morphogenetic proteins for spinal fusion." Spine Journal 5, no. 6 (2005): S240—S249. http://dx.doi.org/10.1016/j.spinee.2005.02.014.

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47

Hruska, Keith A., Suresh Mathew, and Georges Saab. "Bone Morphogenetic Proteins in Vascular Calcification." Circulation Research 97, no. 2 (2005): 105–14. http://dx.doi.org/10.1161/01.res.00000175571.53833.6c.

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48

Winn, Shelley R., Hasan Uludag, and Jeffrey O. Hollinger. "Carrier Systems for Bone Morphogenetic Proteins." Clinical Orthopaedics and Related Research 367 (October 1999): S95—S106. http://dx.doi.org/10.1097/00003086-199910001-00010.

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49

van der Kraan, P. M., E. N. Blaney Davidson, and W. B. van den Berg. "Bone Morphogenetic Proteins and articular cartilage." Osteoarthritis and Cartilage 18, no. 6 (2010): 735–41. http://dx.doi.org/10.1016/j.joca.2010.03.001.

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50

Giannoudis, Peter V., and Thomas A. Einhorn. "Bone morphogenetic proteins in musculoskeletal medicine." Injury 40 (December 2009): S1—S3. http://dx.doi.org/10.1016/s0020-1383(09)00642-1.

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