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1

Chechelnitskaya, S. M., A. V. Baerbach, D. V. Zhuk, V. A. Nikulin, A. G. Rumyantsev, and Yu V. Saraikin. "PERSONALIZED PHYSICAL REHABILITATION OF CHILDREN WITH CANCER." Pediatria. Journal named after G.N. Speransky 100, no. 3 (May 28, 2021): 61–69. http://dx.doi.org/10.24110/0031-403x-2021-100-3-61-69.

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The aim of the research is to study the feasibility and effectiveness of partner medicine programs conducted in full-time and part-time mode in rehabilitation of children with cancer. Materials and methods of research: the article presents a program of physical rehabilitation of children treated for oncological diseases (OD), developed at the Russkoe Pole Medical and Rehabilitation Scientific Center, based on the personal approach and partnerships between the child's family and specialists. The personal approach is based on data of instrumental examination of the actual physical condition of the child and the predicted risks of late toxic complications: somatometry, assessment of energy costs and exercise tolerance, Biomechanical examination of the locomotor apparatus, functional diagnostics of the respiratory and cardiovascular systems. Based on the results, a personal physical rehabilitation program was developed. The process of physical rehabilitation was carried out in a cyclic mode: a hospital period for examination, development of a personal program and implementation training (2 weeks), an inter-hospital period of independent studies with remote support of a doctor and exercise therapy methodologists (from 6 to 12 months). The effectiveness of the developed model was assessed according to three criteria: satisfaction of parents with participation in the program (questionnaire), adherence to recommended physical activity (questionnaire), and assessment of basic mobility (Terrenkur test). The rehabilitation protocol was tested in 135 children aged 6–18 years with hemoblastosis, brain tumors, solid tumors, malignant tumors of bones and skeletal muscles: 61 boys (45,2%) and 74 girls (54,8%). The average age of the participants was 12,6±3,4 years. Results: participation in the program increased parents' confidence in their own ability to help their child with physical exercises at home and formed their willingness to continue the course at home. After discharge, 76% of families followed the recommendations for at least 2 months, 46% additionally applied to recommended organizations for adaptive exercise. Within a period of three months, all families who continue to practice independently have sought advice from exercise therapy methodologists. For three months of home exercises all children adhering to the recommendations have demonstrated an increase in basic mobility. Conclusion: the study confirmed the advisability and desirability for parents of patients to partner with a team of specialists.
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2

Guo, Ying, An Thuy Ngo-Huang, and Jack B. Fu. "Perspectives on Spinal Precautions in Patients Who Have Cancer and Spinal Metastasis." Physical Therapy 100, no. 3 (February 10, 2020): 554–63. http://dx.doi.org/10.1093/ptj/pzz178.

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Abstract Bones are the third most common site for cancer metastases, and the axial skeleton is the most frequent skeletal location. In a postmortem study, bone metastases were reported in 70% of breast and prostate cancer patients. Bone metastases from breast, lung, prostate, thyroid, and kidney cancers account for 80% of all bone metastases. Bone lesions exist in 60% of newly diagnosed multiple myeloma patients. With increasing numbers of people who have survived cancer, many patients with cancer and axial skeletal bony metastases will be seen by physical and occupational therapists. Guidelines are lacking on how to perform physical examinations and provide exercise programs for these patients without compromising the diseased spine. In this article, we discuss the available evidence for similar spinal conditions, the biomechanics of spinal load, and changes associated with posture and weight load. We provide recommendations on how to assess a patient’s strength, how to strengthen without compromising the diseased spine, and how to teach patients to use correct body mechanics during mobility and activities of daily living.
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3

Jepson, Paul D. "Exercise for Strong Bones." Physiotherapy 88, no. 8 (August 2002): 506. http://dx.doi.org/10.1016/s0031-9406(05)60856-5.

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4

Drinkwater, Barbara L. "Exercise and Bones: Lessons Learned from Female Athletes." American Journal of Sports Medicine 24, no. 6_suppl (November 1996): S33—S35. http://dx.doi.org/10.1177/036354659602406s09.

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5

Sundelin, Gunnevi. "Exercise as therapy in chronic diseases." Advances in Physiotherapy 8, no. 2 (January 2006): 49. http://dx.doi.org/10.1080/14038190600830513.

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6

Kujala, U. M. "Benefits of exercise therapy for chronic diseases." British Journal of Sports Medicine 40, no. 1 (January 1, 2006): 3–4. http://dx.doi.org/10.1136/bjsm.2005.021717.

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7

Abraham, Avron. "Exercise for Preventing Common Diseases." Medicine & Science in Sports & Exercise 32, no. 7 (July 2000): 1363. http://dx.doi.org/10.1097/00005768-200007000-00026.

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8

SAKAMOTO, SHIZUO, YOSHIKO NAKAJIMA, KENKI TANAKA, KUNIHIKO AIZAWA, YOKO TANAKA, and TOSHIHIKO IIJIMA. "The exercise therapy to diseases of internal medicine." Juntendo Medical Journal 44, no. 3 (1998): 231–40. http://dx.doi.org/10.14789/pjmj.44.231.

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9

Yung, Lai Ming, Ismail Laher, Xiaoqiang Yao, Zhen Yu Chen, Yu Huang, and Fung Ping Leung. "Exercise, Vascular Wall and Cardiovascular Diseases." Sports Medicine 39, no. 1 (2009): 45–63. http://dx.doi.org/10.2165/00007256-200939010-00004.

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10

Davletiyarova, K. V., L. V. Kapilevich, V. L. Soltanova, Ye B. Baranova, and V. I. Andreyev. "Adaptation possibilities of students going to exercise therapy." Bulletin of Siberian Medicine 10, no. 3 (June 28, 2011): 116–19. http://dx.doi.org/10.20538/1682-0363-2011-3-116-119.

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The cardiointervalography method was used to study adaptation possibilities of students with vascular heart diseases and diseases of musculoskeletal system going to exercise therapy. The physical training organization with use exercise therapy favors the adaptation and functional reserve improvement, and the effect is more in 1st year study students with vascular heart diseases.
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11

Heinonen, A., H. Siev??nen, P. Kannus, P. Oja, C. Snow, and I. Vuori. "EFFECTS OF 9-MONTH HIGH-IMPACT EXERCISE ON BONES AND PHYSICAL PERFORMANCE OF GROWING GIRLS." Medicine & Science in Sports & Exercise 30, Supplement (May 1998): 47. http://dx.doi.org/10.1097/00005768-199805001-00262.

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12

Meyer, Tim, and Andreas Broocks. "Therapeutic Impact of Exercise on Psychiatric Diseases." Sports Medicine 30, no. 4 (2000): 269–79. http://dx.doi.org/10.2165/00007256-200030040-00003.

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13

Pedersen, B. K., and B. Saltin. "Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases." Scandinavian Journal of Medicine & Science in Sports 25 (November 25, 2015): 1–72. http://dx.doi.org/10.1111/sms.12581.

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14

Borsukevych, T. S., O. K. Nikanorov, and V. B. Zaiets. "Modern Views on the Physical Therapy of Patients after Surgical Treatment of Fractures of the Ankle Joint Bones." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 6, no. 3 (June 26, 2021): 8–13. http://dx.doi.org/10.26693/jmbs06.03.008.

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The purpose of the study is to determine and analyze modern means of restoring motor functions used for patients with fractures of the ankle joint bones after surgical treatment. Materials and methods. The work is the result of analysis and generalization of special scientific and methodological literature of domestic and foreign authors and Internet data on the features of the use of modern methods of physical therapy for patients with fractures of the ankle joint bones after surgical treatment. Results and discussion. Physical therapy for patients with fractures of the ankle joint bones is integral to a speedy recovery. Due to the fact that after surgery, it is mandatory to apply a plaster cast or a fixator to the joint for about 6 weeks – the strength of the lower extremities is lost, joint contracture appears, there is aching pain and a decrease in the range of motion. It is necessary to start classes with a physical therapist as early as possible, already on the second day after the operation, if the general condition of the patient is satisfactory. Patients require early postoperative functional physical therapy under the supervision of a physical therapist to improve joint function and proprioception, and to promote edema regression (lymphatic drainage). Patients with fractures associated with ligament injuries especially require proprioceptive neuromuscular facilitation to protect them from the risk of chronic ankle instability. Generally, recovery for patients with this trauma is slow and requires patience. There is some evidence that early introduction of activity during the immobilization period may be beneficial for patients. By doing light ankle exercises, the range of motion is improved, pain disappears and the function of the joint improves. Also, early stress on body weight is associated with many benefits, including better mobility, shorter hospital stays, and earlier return to work. However, there are other claims that early exercise increases the risk of surgical site infection, reoperation, and surgical fixation failure. Given the lack of evidence to determine it should be noted that additional research is needed to address this issue. Conclusions. Current evidence on the physical therapy of fractures of the ankle joint bones after immobilization shows that separate physical therapies do not accelerate the recovery process. This suggests that physical therapy must be comprehensive and must necessarily focus on a progressive and structured exercise program. Also, recent studies have shown that exercise is an effective mean of physical therapy, especially balance exercises
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15

Okechukwu, ChidiebereEmmanuel. "Exercise as preventative therapy against neurodegenerative diseases in older adults." International Journal of Preventive Medicine 10, no. 1 (2019): 165. http://dx.doi.org/10.4103/ijpvm.ijpvm_296_19.

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16

Giangregorio, Lora M., Lehana Thabane, Jonathan D. Adachi, Maureen C. Ashe, Robert R. Bleakney, E. Anne Braun, Angela M. Cheung, et al. "Build Better Bones With Exercise: Protocol for a Feasibility Study of a Multicenter Randomized Controlled Trial of 12 Months of Home Exercise in Women With a Vertebral Fracture." Physical Therapy 94, no. 9 (September 1, 2014): 1337–52. http://dx.doi.org/10.2522/ptj.20130625.

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BackgroundOur goal is to conduct a multicenter randomized controlled trial (RCT) to investigate whether exercise can reduce incident fractures compared with no intervention among women aged ≥65 years with a vertebral fracture.ObjectivesThis pilot study will determine the feasibility of recruitment, retention, and adherence for the proposed trial.DesignThe proposed RCT will be a pilot feasibility study with 1:1 randomization to exercise or attentional control groups.SettingFive Canadian sites (1 community hospital partnered with an academic center and 4 academic hospitals or centers affiliated with an academic center) and 2 Australian centers (1 academic hospital and 1 center for community primary care, geriatric, and rehabilitation services).ParticipantsOne hundred sixty women aged ≥65 years with vertebral fracture at 5 Canadian and 2 Australian centers will be recruited.InterventionThe Build Better Bones With Exercise (B3E) intervention includes exercise and behavioral counseling, delivered by a physical therapist in 6 home visits over 8 months, and monthly calls; participants are to exercise ≥3 times weekly. Controls will receive equal attention.MeasurementsPrimary outcomes will include recruitment, retention, and adherence. Adherence to exercise will be assessed via calendar diary. Secondary outcomes will include physical function (lower extremity strength, mobility, and balance), posture, and falls. Additional secondary outcomes will include quality of life, pain, fall self-efficacy, behavior change variables, intervention cost, fractures, and adverse events. Analyses of feasibility objectives will be descriptive or based on estimates with 95% confidence intervals, where feasibility will be assessed relative to a priori criteria. Differences in secondary outcomes will be evaluated in intention-to-treat analyses via independent Student t tests, chi-square tests, or logistic regression. The Bonferroni method will be used to adjust the level of significance for secondary outcomes so the overall alpha level is .05.LimitationsNo assessment of bone mineral density will be conducted. The proposed definitive trial will require a large sample size.ConclusionsThe viability of a large-scale exercise trial in women with vertebral fractures will be evaluated, as well as the effects of a home exercise program on important secondary outcomes.
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17

Moore, Geoffrey E. "Exercise Management in Persons with Multiple Chronic Diseases." Medicine & Science in Sports & Exercise 40, Supplement (May 2008): 39. http://dx.doi.org/10.1249/01.mss.0000320868.98282.42.

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18

Bruns, Danielle R., and Lori A. Walker. "Exercise and Pharmacology as Medicine for Cardiovascular Diseases." Exercise and Sport Sciences Reviews 46, no. 1 (January 2018): 2–3. http://dx.doi.org/10.1249/jes.0000000000000133.

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19

Weber, Manuel, Falk Wehrhan, James Deschner, Janina Sander, Jutta Ries, Tobias Möst, Aline Bozec, Lina Gölz, Marco Kesting, and Rainer Lutz. "The Special Developmental Biology of Craniofacial Tissues Enables the Understanding of Oral and Maxillofacial Physiology and Diseases." International Journal of Molecular Sciences 22, no. 3 (January 28, 2021): 1315. http://dx.doi.org/10.3390/ijms22031315.

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Maxillofacial hard tissues have several differences compared to bones of other localizations of the human body. These could be due to the different embryological development of the jaw bones compared to the extracranial skeleton. In particular, the immigration of neuroectodermally differentiated cells of the cranial neural crest (CNC) plays an important role. These cells differ from the mesenchymal structures of the extracranial skeleton. In the ontogenesis of the jaw bones, the development via the intermediate stage of the pharyngeal arches is another special developmental feature. The aim of this review was to illustrate how the development of maxillofacial hard tissues occurs via the cranial neural crest and pharyngeal arches, and what significance this could have for relevant pathologies in maxillofacial surgery, dentistry and orthodontic therapy. The pathogenesis of various growth anomalies and certain syndromes will also be discussed.
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20

Chen, Haiyan. "The role of Tai Chi Chuan exercise on osteoporosis prevention and treatment in postmenopausal women." Alternative Medicine Studies 1, no. 1 (September 26, 2011): 10. http://dx.doi.org/10.4081/ams.2011.e10.

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Osteoporosis is a disease characterized by fragile bones and high susceptibility to low trauma fractures. Tai Chi, an ancient Chinese mind-body exercise that is reported to enhance muscle function, balance and flexibility, and to reduce pain, depression and anxiety, may safely and effectively be used to prevent or treat osteoporosis. The aim of this review is to evaluate the evidence for Tai Chi as an intervention to reduce rate of bone loss in postmenopausal women. A literature search on randomized controlled trials (RCTs), prospective cohort studies, and cross-sectional studies that included Tai Chi as an intervention, and had at least 1 outcome related to measurement of bone metabolism were identified in PubMed/Medline. Twenty-one controlled studies were identified in the database, which suggested Tai Chi slowed down the loss of bone mineral density in most postmenopausal women, improved balance and strength, relieves pain from arthritis, and improved mental strength so they can cope better with chronic diseases. Regular Tai Chi Chuan exercise is beneficial for retarding bone loss in the weight-bearing bones of postmenopausal women.
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21

Benatti, Fabiana B., and Bente K. Pedersen. "Exercise as an anti-inflammatory therapy for rheumatic diseases—myokine regulation." Nature Reviews Rheumatology 11, no. 2 (November 25, 2014): 86–97. http://dx.doi.org/10.1038/nrrheum.2014.193.

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22

Kemmler, Wolfgang, and Simon von Stengel. "Exercise Frequency, Health Risk Factors, and Diseases of the Elderly." Archives of Physical Medicine and Rehabilitation 94, no. 11 (November 2013): 2046–53. http://dx.doi.org/10.1016/j.apmr.2013.05.013.

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23

Davletiyarova, K. V., V. L. Soltanova, L. V. Kapilevich, and V. I. Andreyev. "Correction of disordered equilibrium function in students through exercise therapy." Bulletin of Siberian Medicine 8, no. 3 (June 28, 2009): 23–26. http://dx.doi.org/10.20538/1682-0363-2009-3-23-26.

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The method of stabilography was used to study the equilibrium function in students with vascular heart diseases and diseases of musculoskeletal system going in for exercise therapy (ET). The organization of physical training with the use exercise therapy favors the normalization of the equilibrium function and coordination abilities, and the effect is more pronounced in the group of students with diseases of the musculoskeletal system.
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24

Abeeshna Ashok and Dhanesh Kumar K U. "Osteogenesis imperfecta and physical therapy: A review of recent trends during the COVID-19 pandemic." International Journal of Research in Pharmaceutical Sciences 11, SPL1 (September 30, 2020): 951–56. http://dx.doi.org/10.26452/ijrps.v11ispl1.3243.

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Osteogenesis Imperfecta (OI) is a genetic disease affecting the bones. The main feature of the disease is bone fragility and low bone density. Between 6 and 7 in 100,000 people are affected by the disease. The clinical features are painful bones, bowlegs, short stature, enlarged head, bone fractures, hearing loss, and scoliosis. It is classified into four types: I to IV. Subgroups have been identified, whereby types V, VI, and VII are not associated with collagen mutation. Many patients experience deformities resulting in reduced mobility and difficulty to carry out daily activities. COVID-19 is defined as "a mild to severe respiratory illness that is caused by a coronavirus, is transmitted chiefly by contact with infectious material (such as respiratory droplets) or with objects or surfaces contaminated by the causative virus, and is characterized especially by fever, cough and shortness of breath and may progress to pneumonia and respiratory failure". During the lock down, OI patients suffer from reduced physical activity. Home exercise programmes/physical therapy and the number of clinical visits is also reduced. Rehabilitation sessions should include strengthening, developmental exercises, positioning, standing, and walking, whole-body vibration exercises, and aerobic exercise. Continuous physiotherapy is recognized as one of the essential conservative treatment options. A search was carried out of databases, including CINHAL, Embase, Cochrane, Pubmed, and Google Scholar. This was used to answer the following research questions: What is OI? How is it being treated? How did rehabilitation change during the COVID-19 pandemic? This is the first extensive review of research on the topic.
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25

Luan, Xin, Xiangyang Tian, Haixin Zhang, Rui Huang, Na Li, Peijie Chen, and Ru Wang. "Exercise as a prescription for patients with various diseases." Journal of Sport and Health Science 8, no. 5 (September 2019): 422–41. http://dx.doi.org/10.1016/j.jshs.2019.04.002.

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26

Wang, Ruwen, Haili Tian, Dandan Guo, Qianqian Tian, Ting Yao, and Xingxing Kong. "Impacts of exercise intervention on various diseases in rats." Journal of Sport and Health Science 9, no. 3 (May 2020): 211–27. http://dx.doi.org/10.1016/j.jshs.2019.09.008.

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27

Vardar, Tonguç, and ,. İbrahim Kubilay Türkay. "Regular Exercise, Thombocyte, Collagen and Breast Cancer." Pakistan Journal of Medical and Health Sciences 15, no. 7 (July 30, 2021): 2172–74. http://dx.doi.org/10.53350/pjmhs211572172.

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Platelets, which play a very important role in the continuation of vital activities, play an important role in blood coagulation. Various chronic diseases can reduce the platelets produced by our body below the standard level or increase them in a dangerous way. Diseases related to malignancy, that is, malignant tumors, come at the beginning of the diseases that disrupt the platelet balance. One of them is breast cancer. Breast cancer is a type of cancer that occurs as a result of mutations in the BRCA1 (17q21) and P53 (17p13) genes located on the 17th chromosome and the BRCA2 gene located on the 13th chromosome. It is known that the amount of bone mass due to estrogen hormone is closely related to the formation of breast cancer. Collagen is the protein that forms bones, cartilage fibers and joints, which are the building blocks of our motor (movement) system. The main protein that forms the main structure of the bone is Type I collagen and about 30 types of collagen have been defined. It acts as a support for bone and cartilage tissue. Regular exercise, on the other hand, is a type of regular, systematic and programmed physical activity done with the aim of improving the physical and mental state of the person. There are many studies that found that exercise increases the tendency of platelet aggregation (aggregation, aggregation, aggregation). In addition, there are scientific studies that show that regular exercise and regularly used collagen stop the progression of breast cancer. The aim of this scientific review is to describe the relationship between platelet, collagen, breast cancer and regular exercise. Keywords: Quiet eye, Platelet, Collagen, Breast Cancer, Regular exercise
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28

Fowler, William M., and Walter R. Frontera. "Adaptations to Exercise Training in Humans and Animals with Neuromuscular Diseases." American Journal of Physical Medicine & Rehabilitation 81, Supplement (November 2002): S80. http://dx.doi.org/10.1097/00002060-200211001-00009.

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29

Sulyma, Vadym, Andrii Sribniak, Roman Bihun, and Zinovii Sribniak. "Emphysematous Osteomyelitis: Review of the Literature." Ortopedia Traumatologia Rehabilitacja 22, no. 3 (June 30, 2020): 153–59. http://dx.doi.org/10.5604/01.3001.0014.3231.

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This article presents a detailed review of the 49 reported cases of emphysematous osteomyelitis. Infection of the bones and joints usually developed in various locations of patients with concomitant diseases. The treatment includes antibiotic therapy and minor surgery, usually drainage.
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30

Evloev, R. Yu, В. N. Reshetin, and Z. I. Urazgildeev. "Treatment for Gunshot Fractures of Upper Extremity Long Bones with Nerve Injuries." N.N. Priorov Journal of Traumatology and Orthopedics 11, no. 3 (September 15, 2004): 52. http://dx.doi.org/10.17816/vto200411352.

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The treatment results of gunshot fractures with nerve trunk injuries of upper extremity bones were summarized for the period from 1995 to 2000. Thirty patients had the injury at the level of humeral segment, 15 patients — at the level of forearm and 4 patients were with injuries of the elbow joint. The debridement and extrafocal osteosynthesis with early, i.e. 4 weeks after trauma, surgical interventions on bone fragments and nerve trunks were performed. In anatomically safe nerve trunk, neurolysis and bone fragment compression using special device were carried out. In nerve injury, resection of bone fragment ends with following stable osteosynthesis and perineural suturing of nerve was performed. In fractures of forearm bones with large defect of nerve trunk the autografting of nerve was done. In early postoperative period complex drug therapy was prescribed. After fracture healing physiotherapy, massage and exercise therapy was started. Long-term results showed that 82% of patients had positive outcomes. Duration of treatment using suggested tactics was shorter in comparison with traditional multy-step method.
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31

Eathorne, Scott. "ACSM's Exercise Management for Persons with Chronic Diseases and Disabilities." Medicine& Science in Sports & Exercise 30, no. 9 (September 1998): 1461. http://dx.doi.org/10.1249/00005768-199809000-00019.

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32

Eathorne, Scott. "ACSM's Exercise Management for Persons with Chronic Diseases and Disabilities." Medicine& Science in Sports & Exercise 30, no. 9 (September 1998): 1461. http://dx.doi.org/10.1097/00005768-199809000-00019.

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33

Cup, Edith H., Allan J. Pieterse, Jessica M. ten Broek-Pastoor, Marten Munneke, Baziel G. van Engelen, Henk T. Hendricks, Gert J. van der Wilt, and Rob A. Oostendorp. "Exercise Therapy and Other Types of Physical Therapy for Patients With Neuromuscular Diseases: A Systematic Review." Archives of Physical Medicine and Rehabilitation 88, no. 11 (November 2007): 1452–64. http://dx.doi.org/10.1016/j.apmr.2007.07.024.

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34

Bertapelli, Fabio. "ACSM’s Exercise Management for Persons With Chronic Diseases and Disabilities, 4th ed." Adapted Physical Activity Quarterly 34, no. 2 (April 2017): 201–2. http://dx.doi.org/10.1123/apaq.2017-0066.

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35

Severo, Cecília Bittencourt, Flávio de Mattos Oliveira, Lenine Cunha, Vlademir Cantarelli, and Luiz Carlos Severo. "Disseminated nocardiosis due to Nocardia farcinica: diagnosis by thyroid abscess culture." Revista do Instituto de Medicina Tropical de São Paulo 47, no. 6 (December 2005): 355–58. http://dx.doi.org/10.1590/s0036-46652005000600009.

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A previously healthy 75-year-old white male dentist presented with a 6-month history of low-back pain treated with chronic steroid therapy had a Nocardia farcinica infection diagnosed by aspirate of thyroid abscess and six blood cultures. Despite the treatment with parenteral combination of trimethoprim/sulfamethoxazole, the patient failed to respond and died after two days of therapy. Autopsy revealed disseminated nocardiosis, involving lungs with pleural purulent exudate in both sides, heart, thyroid, kidneys, brain, bones, and lumbosacral soft tissue with destruction of L2-L4.
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Oorschot, Sander, Merel-Anne Brehm, Annerieke van Groenestijn, Frans Nollet, and Eric Voorn. "Optimizing Protocol Selection for Cardiopulmonary Exercise Testing in Slowly Progressive Neuromuscular Diseases." Archives of Physical Medicine and Rehabilitation 102, no. 10 (October 2021): e9. http://dx.doi.org/10.1016/j.apmr.2021.07.415.

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37

Webborn, A. D. J. "ACSM's exercise management for persons with chronic diseases and disabilities." British Journal of Sports Medicine 31, no. 4 (December 1, 1997): 354. http://dx.doi.org/10.1136/bjsm.31.4.354-b.

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38

Gunter, Kathy, and Adrienne J. McNamara. "Successful Translation of Better Bones and Balance: a Community-Based Fall and Fracture Risk Reduction Exercise Program for Older Adults." Medicine & Science in Sports & Exercise 42 (May 2010): 48. http://dx.doi.org/10.1249/01.mss.0000384917.21798.29.

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39

Goolsby, Marci A., and Nicole Boniquit. "Bone Health in Athletes." Sports Health: A Multidisciplinary Approach 9, no. 2 (November 30, 2016): 108–17. http://dx.doi.org/10.1177/1941738116677732.

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Context: The health of the skeletal system is important for athletes young and old. From the early benefits of exercise on bones to the importance of osteoporosis prevention and treatment, bone health affects the ability to be active throughout life. Evidence Acquisition: PubMed articles dating from 1986 to 2016 were used for the review. Relevant terms such as keywords and section titles of the article were searched and articles identified were reviewed for relevance to this article. Study Design: Clinical review. Level of Evidence: Levels 1 through 4 evidence included. Results: There is strong evidence that exercise benefits bone health at every age and is a critical factor in osteoporosis prevention and treatment. Vitamin D, calcium, and hormones play vital roles in ensuring optimal bone health. When there is an imbalance between exercise and nutrition, as seen in the female athlete triad, bone health is compromised and can lead to bone stress injuries and early osteoporosis. Both of these can lead to morbidity and lost time from training and competition. Thus, early recognition and appropriate treatment of the female athlete triad and other stress fracture risk factors are vital to preventing long-term bone health problems. Conclusion: To optimize bone health, adequate nutrition, appropriate weightbearing exercise, strength training, and adequate calcium and vitamin D are necessary throughout life.
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40

DiMauro, Salvatore, and Michelangelo Mancuso. "Mitochondrial Diseases: Therapeutic Approaches." Bioscience Reports 27, no. 1-3 (June 13, 2007): 125–37. http://dx.doi.org/10.1007/s10540-007-9041-4.

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Therapy of mitochondrial encephalomyopathies (defined restrictively as defects of the mitochondrial respiratory chain) is woefully inadequate, despite great progress in our understanding of the molecular bases of these disorders. In this review, we consider sequentially several different therapeutic approaches. Palliative therapy is dictated by good medical practice and includes anticonvulsant medication, control of endocrine dysfunction, and surgical procedures. Removal of noxious metabolites is centered on combating lactic acidosis, but extends to other metabolites. Attempts to bypass blocks in the respiratory chain by administration of electron acceptors have not been successful, but this may be amenable to genetic engineering. Administration of metabolites and cofactors is the mainstay of real-life therapy and is especially important in disorders due to primary deficiencies of specific compounds, such as carnitine or coenzyme Q10. There is increasing interest in the administration of reactive oxygen species scavengers both in primary mitochondrial diseases and in neurodegenerative diseases directly or indirectly related to mitochondrial dysfunction. Aerobic exercise and physical therapy prevent or correct deconditioning and improve exercise tolerance in patients with mitochondrial myopathies due to mitochondrial DNA (mtDNA) mutations. Gene therapy is a challenge because of polyplasmy and heteroplasmy, but interesting experimental approaches are being pursued and include, for example, decreasing the ratio of mutant to wild-type mitochondrial genomes (gene shifting), converting mutated mtDNA genes into normal nuclear DNA genes (allotopic expression), importing cognate genes from other species, or correcting mtDNA mutations with specific restriction endonucleases. Germline therapy raises ethical problems but is being considered for prevention of maternal transmission of mtDNA mutations. Preventive therapy through genetic counseling and prenatal diagnosis is becoming increasingly important for nuclear DNA-related disorders. Progress in each of these approaches provides some glimmer of hope for the future, although much work remains to be done.
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Booth, F. W., S. E. Gordon, C. J. Carlson, and M. T. Hamilton. "Waging war on modern chronic diseases: primary prevention through exercise biology." Scandinavian Journal of Medicine & Science in Sports 10, no. 5 (July 7, 2008): 308–9. http://dx.doi.org/10.1111/j.1600-0838.2000.100509.x.

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Oh, Sechang, Kiyoji Tanaka, Eiji Warabi, and Junichi Shoda. "Exercise Reduces Inflammation and Oxidative Stress in Obesity-Related Liver Diseases." Medicine & Science in Sports & Exercise 45, no. 12 (December 2013): 2214–22. http://dx.doi.org/10.1249/mss.0b013e31829afc33.

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Kelley, George A., and Kristi Sharpe Kelley. "Exercise and Anxiety in Adults with Arthritis and Other Rheumatic Diseases." Medicine & Science in Sports & Exercise 50, no. 5S (May 2018): 72. http://dx.doi.org/10.1249/01.mss.0000535320.97212.bf.

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Sugiyama, Toshihiro, Toshiaki Takaki, Kenya Sakanaka, Hiroki Sadamaru, Koji Mori, Yoshihiko Kato, Toshihiko Taguchi, and Takashi Saito. "Warfarin-induced impairment of cortical bone material quality and compensatory adaptation of cortical bone structure to mechanical stimuli." Journal of Endocrinology 194, no. 1 (July 2007): 213–22. http://dx.doi.org/10.1677/joe-07-0119.

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Long-term warfarin use has been reported to increase fracture risk of rib and vertebra but not hip in elderly patients, but the mechanisms remain unknown. We hypothesized that warfarin would impair bone material quality but could not weaken bone strength under conditions with higher mechanical stimuli. To test this hypothesis, rats were randomized to vehicle or warfarin group at 4 weeks of age and subsequently weight matched into a sedentary or jumping exercise group at 12 weeks of age. At 6 months of age, osteocalcin content, bone mineral density (BMD), mineral size, material properties, morphological parameters, and biomechanical properties of cortical bones were evaluated. In order to seek evidence for a common mechanism of action, effects of nucleation rate of mineral crystals on their rigidity were also investigated using computer simulation. In humeral cortical bones, warfarin did not change BMD, but markedly decreased osteocalcin content, diminished mineral size, and impaired material hardness. Consistent with these results, our computer-simulation model showed that osteocalcin-induced delay of mineral crystal nucleation decreased mineral formation rate, increased mean and distribution of mineral sizes, and strengthened mineral rigidity. In tibial cortical bones, warfarin decreased material ultimate stress; however, under jumping exercise, warfarin increased cross-sectional total and bone areas of these tibiae and completely maintained their biomechanical properties including work to failure. Collectively, our findings suggest that long-term warfarin therapy weakens rib and vertebra by impairing cortical bone material quality due to a marked decrease in osteocalcin content but could not reduce hip strength through compensatory adaptation of cortical bone structure to higher mechanical stimuli.
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Takken, Tim. "Chronic Diseases, Exercise, and Physical Activity in Childhood: 2015 in Review." Pediatric Exercise Science 28, no. 1 (February 2016): 52–54. http://dx.doi.org/10.1123/pes.2016-0015.

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The year of 2015 was a fruitful year in the field of chronic diseases, exercise, and physical activity in childhood. Many interesting papers came out on this topic. Exercise testing and prescription in children with chronic disease and disability is an increasingly studied area in which many disciplines are involved including pediatric physical therapy, medicine, nursing, physical education, and exercise physiology. This multidisciplinary aspect is reflected in the journals in which my highlighted publications (below) were published. Because no single discipline has the ownership of exercise testing and prescription and because different disciplines use different jargon, it is difficult to have the scientific knowledge translated to the clinic. A few years ago we initiated the Pediatric Exercise Medicine Network (PEMNet) to close this knowledge translation gap.
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Pastari, Martha, and Syokumawena Syokumawena. "The Effect of Giving Cold Therapy to Decreased Pain Sprain Ankle Basket Ball Players." Physical education, sport and health culture in modern society, no. 1 (49) (March 31, 2020): 102–6. http://dx.doi.org/10.29038/2220-7481-2020-01-102-106.

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Sprain, is an injury to a joint that results in a torn ligament that functions as a binding between bones and as a stabilizer for the joint that occurs due to excessive pressure and sudden movements repeatedly. It is estimated that nearly 1,6 million injuries occur in connection with basketball in Indonesia. The epidemiology of injuries to male basketball players during training is 4,3 per 1000 while the competition is 9,9 per 1000. This study is an experimental study with a Two Group Pre-Test and Post-Test Design. The research subjects were 30 permanent members of the Bangau Basketball Club which were divided into 2 groups: O1 group was a group that was given cold therapy before training alone, O2 group was a group that was given cold therapy after exercise alone. The study was conducted in October-November 2018. There was a difference between pain intensity and the degree of ankle sprain O1 group before and after exercise with the pain intensity difference test value of 0,000 and the value of the ankle sprain degree difference test result of 0,029 (p <0,05). There was a difference between the intensity of pain and the degree of ankle sprain in the O2 group before and after exercise with the test value of the pain intensity difference of 0,024 and the value of the test result of the degree of ankle sprain difference of 0,047 (p <0,05). Wilcoxon test results showed that there was an effect of cold therapy to reduce ankle sprain pain with p <0,05.
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Chaplynska, Nataliia, Viktoriia Rudnyk, Liubov Skrypnyk, and Nataliia Matkovska. "Clinical observation of generalized sarcoidosis with damage of bones." Pharmacia 67, no. 4 (October 2, 2020): 193–97. http://dx.doi.org/10.3897/pharmacia.67.e54473.

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Sarcoidosis is a multisystem disease of unknown etiology, at the basis of which there is an inflammatory granulation epithelioid process without a pronounced exudative reaction and without caseous necrosis. This disease has various manifestations. The aim of the study was to investigate the clinical case of generalized sarcoidosis with bone lesion in a patient M., born in 1987. There were performed X-ray examinations, computed tomography (CT), fibrobronchoscopy, determination of calcium levels, angiotensin converting enzyme (ACE), soluble IL-2 receptor in the blood. Dynamic observation was performed for 10 months. The patient started methylprednisolone therapy at a dose of 20 mg/day. Significant positive effect of this treatment was noted. Thus, when patients complain of the bone and joint system problems, examination plan should include radiological examination of thoracic organs, which will allow us to avoid late diagnosis of sarcoidosis or other multisystem diseases that may have similar clinical manifestations.
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Guo, Shanshan, Yiru Huang, Yan Zhang, He Huang, Shangyu Hong, and Tiemin Liu. "Impacts of exercise interventions on different diseases and organ functions in mice." Journal of Sport and Health Science 9, no. 1 (January 2020): 53–73. http://dx.doi.org/10.1016/j.jshs.2019.07.004.

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49

Hardman, Adrianne E. "Exercise in the prevention of atherosclerotic, metabolic and hypertensive diseases: A review." Journal of Sports Sciences 14, no. 3 (June 1996): 201–18. http://dx.doi.org/10.1080/02640419608727705.

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Ginting, Raynald Ignasius, Sabirin Berampu, Siti Sarah Bintang, Ni Nyoman Ayu Tamala Hardis, and Engraini Teja. "WORKSHOP NERVE GLIDING EXERCISE DAN PEMBERIAN ULTRA SOUND (US) TERHADAP PENURUNAN NYERI PADA KASUS CARPAL TUNNEL SYNDROME DI GRANDMED LUBUK PAKAM." JURNAL PENGMAS KESTRA (JPK) 1, no. 1 (June 30, 2021): 120–24. http://dx.doi.org/10.35451/jpk.v1i1.747.

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The problem that often occurs for workers is Carpal tunnel syndrome (CTS). Carpal tunnel syndrome is a disorder of the hand due to compression of the median nerve in the carpal tunnel, either due to adhesions or abnormalities of the small bones of the hand. The median nerve innervates the thumb, index finger, middle finger and part of the ring finger, so that pain and parathesia can be felt in these areas. One way of non-pharmacological therapy that can be used in CTS is through the provision of nerve gliding exercise. Nerve gliding exercise and the administration of ultra sound (US) modality are done with the aim of reducing pressure on the wrist so that pain can be reduced. The results of this service activity stated that as many as 94% of participants as physiotherapists had understood and were able to use nerve gliding exercise and Ultra Sound (US) for pain reduction in CTS cases.
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