Log in

Relevant bibliographies by topics / Booster Vaccines / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Booster Vaccines.

Dissertations / Theses on the topic 'Booster Vaccines'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 37 dissertations / theses for your research on the topic 'Booster Vaccines.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Filgueira, Fabiana Ariston. "Estudo de títulos protetores para o vírus de hepatite B após esquema vacinal de três doses e \"booster\" em crianças com HIV." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-24112008-103206/.

Full text

Abstract:

INTRODUÇÃO: A hepatite B é uma enfermidade para a qual não existe tratamento curativo efetivo e que pode determinar graves conseqüências, como o desenvolvimento de cirrose e carcinoma hepático. Segundo dados da OMS, mais de dois bilhões de pessoas estão infectadas pelo vírus da hepatite B e esta doença é responsável por 500.000 a um milhão de óbitos por ano, em todo o mundo. Em pacientes com infecção pelo HIV, é freqüente a co-infecção pelo vírus da hepatite B, pelo fato de serem vírus que compartilham modos semelhantes de transmissão. Em vista dessa problemática, a adequada imunização dos pac

APA, Harvard, Vancouver, ISO, and other styles

2

Humby, Samantha A. "An investigation of the effects of helminth worm infection on the capacity of HIV vaccines to boost vaccine-generated immune responses." Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/24896.

Full text

Abstract:

To protect against sexual transmission, successful future HIV vaccines will likely be given to adolescents as a booster subsequent to primary immunization during infancy. In sub-Saharan Africa (SSA), a large proportion of children are chronically infected with a variety of helminths. These infections may suppress the ability of a host to elicit vaccine-induced Th1 responses that are considered important for a successful HIV vaccine. This study investigated the effect of chronic helminthic infection on the boosting capacity of a poxvirus-protein HIV vaccine regimen (SAAVI MVA-C and Env gp140 pr

APA, Harvard, Vancouver, ISO, and other styles

3

Rodriguez, Pozo Andre. "Deep characterization of the Modified Vaccinia Ankara vaccine induced B cell response in the context of prime-boost immunization." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS061.

Full text

Abstract:

Les anticorps sont des corrélats de protection pour différents vaccins qui sont sur le marché. Une meilleure connaissance des modes d’action des vaccins au cours de la primo-vaccination et des rappels sont nécessaires pour améliorer ceux déjà disponibles et ceux en cours de développement.En développant un pipeline d’analyse des données de cytométrie en masse, nous avons étudié l’hétérogénéité des cellules B de macaques et établi un atlas des cellules B dans diffèrent organes.Nous avons démontré que les cellules B du sang sont enrichies au cours du temps après la primo vaccination et/ou le rapp

APA, Harvard, Vancouver, ISO, and other styles

4

Bråve, Andreas. "Prime-boost immunization strategies against HIV-1 /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-327-6/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Badamchi-Zadeh, Alexander. "Heterologous prime-boost vaccine regimens against Chlamydia trachomatis." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/25021.

Full text

Abstract:

Chlamydia trachomatis is the most common bacterial sexually transmitted disease in man and despite decades of effort, there is still no protective vaccine. Left untreated, genital infection can lead to pelvic inflammatory disease, ectopic pregnancy, and infertility. However, infection-induced immunity in both animal models and humans indicates a strong role for CD4+ Th1-biased immune responses. Using a multi-component vaccine approach we assessed the immunogenicity and protective efficacy of novel plasmid DNA, Adenovirus 5 (HuAd5) and modified vaccinia Ankara (MVA) vectors each containing a ma

APA, Harvard, Vancouver, ISO, and other styles

6

Lange, Uta Gisela. "Heterologous prime-boost strategies in the development of novel vaccines against leishmaniasis." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619876.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Vaine, Michael. "Antibody Responses Elicited by DNA Prime-Protein Boost HIV Vaccines: A Dissertation." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/462.

Full text

Abstract:

The best known correlate of protection provided by vaccines is the presence of pathogen specific antibodies after immunization. However, against the Human Immunodeficiency Virus-1 (HIV-1) the mere presence of antibodies specific for the viral Envelope (Env) protein is not sufficient to provide protection. This necessitates in depth study of the humoral responses elicited during infection and by vaccination. While a significant amount of effort has been invested in studying the evolution of antibody responses to viral infection, only limited progress in understanding antibody responses elicited

APA, Harvard, Vancouver, ISO, and other styles

8

Biswas, Sumi. "Prime boost vaccination with viral vectors targeting apical membrane antigen 1." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:a17ab4e4-9b81-4ab3-b02f-41d9da36c6ab.

Full text

Abstract:

Apical membrane antigen 1 (AMA1) is a leading candidate vaccine antigen against blood stage malaria and several clinical trials using mostly protein-in-adjuvant vaccines have shown limited success. This thesis describes the development of recombinant adenoviral (AdHu5) and poxviral (MVA) vectors encoding AMA1 from Plasmodium chabaudi murine parasites. In this murine malaria model, AdHu5 and MVA encoding AMA1 when used in a heterologous prime boost regime showed excellent immunogenicity, both humoral and cellular. The vaccination regime was protective against blood stage challenge and both anti

APA, Harvard, Vancouver, ISO, and other styles

9

Bernelin-Cottet, Cindy. "Développement d'un vaccin à ADN contre le virus du Syndrome Dysgénésique et Respiratoire Porcin (PRRSV)." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLA004/document.

Full text

Abstract:

Le Syndrome Dysgénésique et Respiratoire Porcin (PRRS) est la maladie infectieuse endémique la plus couteuse en élevage porcin dont l'agent responsable est un Arterivirus, le PRRSV, qui présente une grande diversité génétique. L'infection par le PRRSV est fréquemment associée à l'infection par les virus influenza. La vaccination est une méthode de lutte adaptée contre ces virus. Dans le cas du PRRSV, les vaccins les plus utilisés sont des virus vivants modifiés (MLV) qui induisent une immunité protectrice peu efficace contre les variants viraux. Dans le cas du virus influenza, les vaccins inac

APA, Harvard, Vancouver, ISO, and other styles

10

Buglione-Corbett, Rachel. "Adjuvant-Specific Serum Cytokine Profiles in the Context of a DNA Prime-Protein Boost HIV-1 Vaccine: A Dissertation." eScholarship@UMMS, 2013. https://escholarship.umassmed.edu/gsbs_diss/666.

Full text

Abstract:

In recent years, heterologous prime-boost vaccination constructs have emerged as a promising strategy to generate broad and protective immunity against a variety of pathogens. The utility of DNA vaccination in priming the immune system, in particular, has improved the immunogenicity of vaccines against difficult pathogens such as HIV-1. In addition, many vaccine formulations include an adjuvant to augment immune responses. However, the mechanisms and profiles of many adjuvants remain largely unknown, particularly in the context of such combination immunization approaches. My thesis research st

APA, Harvard, Vancouver, ISO, and other styles

11

Buglione-Corbett, Rachel. "Adjuvant-Specific Serum Cytokine Profiles in the Context of a DNA Prime-Protein Boost HIV-1 Vaccine: A Dissertation." eScholarship@UMMS, 2004. http://escholarship.umassmed.edu/gsbs_diss/666.

Full text

Abstract:

In recent years, heterologous prime-boost vaccination constructs have emerged as a promising strategy to generate broad and protective immunity against a variety of pathogens. The utility of DNA vaccination in priming the immune system, in particular, has improved the immunogenicity of vaccines against difficult pathogens such as HIV-1. In addition, many vaccine formulations include an adjuvant to augment immune responses. However, the mechanisms and profiles of many adjuvants remain largely unknown, particularly in the context of such combination immunization approaches. My thesis research st

APA, Harvard, Vancouver, ISO, and other styles

12

Baxter, Katherine Elizabeth. "Developing an Oncolytic Prime-Boost Vaccine Targeting the Tumour Associated Antigen Mesothelin for the Treatment of Pancreatic Cancer." Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/40024.

Full text

Abstract:

Pancreatic cancer (PDAC) affects 4400 Canadians each year and with 5year survival rates <8%, there is clearly an unmet need for new therapeutic approaches for treating this deadly disease. Herein I report the development of a surgical model of PDAC that recapitulates many of the hallmarks of human disease and has an immune infiltrate consisting of T cells and suppressive regulatory T cells and myeloid derived suppressor cells. This model allows the exploration of new therapeutics that can be used in combination with surgical resection of primary tumours. Furthermore, I propose that the use of

APA, Harvard, Vancouver, ISO, and other styles

13

Bahuaud, Mathilde. "Vaccination anti-pneumococcique chez les sujets à risque d'infections invasives à pneumocoques et prévention de l'hyporéponse Immunogenicity and persistence of the 13-valent pneumococcal conjugate vaccine (PCV13) in patients with untreated smoldering multiple myeloma (SMM): a pilot study Immunogenicity and persistence of a prime-boost re-vaccination strategy for pneumococcal vaccines in patients with rheumatoid arthritis Pneumococcal vaccination in patients with systemic lupus erythematosus: a multicenter placebo-controlled randomized double-blind study Prevention of hyporesponsiveness by modulation of schedule and doses of pneumococcal vaccine immunization." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCB067.

Full text

Abstract:

Deux vaccins sont actuellement disponibles pour la prévention des infections invasives à pneumocoques (IIP) : un vaccin polysaccharidique Pneumovax® (PPV23) et un vaccin conjugué Prevenar13® (PCV13), induisant respectivement une protection contre 23 et 13 sérotypes. Le PPV23 est considéré comme faiblement immunogène, en particulier chez les personnes âgées et les patients immunodéprimés. Le PCV13, en revanche, en raison de la conjugaison à une protéine porteuse, présente l'avantage d'induire une réponse immunitaire T-dépendante, non observée avec le vaccin PPV23. Dans notre travail nous avons

APA, Harvard, Vancouver, ISO, and other styles

14

Bissa, M. "CONSTRUCTION AND EVALUATION OF RECOMBINANT IMMUNOGENS AS THERAPEUTIC VACCINES AGAINST HPV-RELATED CANCERS." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/244949.

Full text

Abstract:

Background Considering the high number of new cases of cervical cancer each year caused by human papilloma viruses (HPVs), the development of an effective vaccine for the prevention and therapy of HPV-associated cancers, and in particular against the high-risk HPV-16 genotype, remains a priority. Vaccines expressing the E6 and E7 proteins, which are detectable in all HPV-positive pre-cancerous and cancer cells, might support the treatment of HPV-related lesions and clear already established tumors. Methods In this study, DNA and fowlpox virus recombinants expressing the E6F47R and E7GGG m

APA, Harvard, Vancouver, ISO, and other styles

15

Caproni, Elena. "Distinctive innate immune signatures at injection site boost the adaptive response to flu subunit vaccine." Doctoral thesis, Università degli studi di Padova, 2011. http://hdl.handle.net/11577/3427448.

Full text

Abstract:

Vaccine adjuvants activate specific innate immune pathways which boost the adaptive responses to co-administered antigens. Experimental data in mouse and human have shown that the efficacy of vaccine adjuvants is often antigen-dependent. For example, alum has been used for years as an efficient adjuvant for many subunit vaccines including Hepatitis B and Diphteria-Tetanus, but is not very efficient in enhancing the response to flu HA antigen. Recently, several human studies have shown that oil-in-water emulsions such as MF59 are superior to alum in enhancing the response to flu subunit vaccin

APA, Harvard, Vancouver, ISO, and other styles

16

Costa, Matthew R. "FC Receptor-Mediated Activities of Env-Specific Monoclonal Antibodies Generated from Human Volunteers Receiving a DNA Prime-Protein Boost HIV Vaccine: A Dissertation." eScholarship@UMMS, 2016. https://escholarship.umassmed.edu/gsbs_diss/866.

Full text

Abstract:

Human immunodeficiency type 1 (HIV-1) is able to elicit broadly potent neutralizing antibodies in a very small subset of individuals only after several years’ infection and as a result, vaccines that elicit these types of antibodies have been difficult to design. The RV144 trial showed that a moderate protection is possible, which may correlate with antibody dependent cellular cytotoxicity (ADCC) activity. Previous studies in the Lu lab demonstrated that in an HIV-1 vaccine phase I trial, DP6-001, a polyvalent Env DNA prime-protein boost formulation, could elicit potent and broadly reactive, g

APA, Harvard, Vancouver, ISO, and other styles

17

Costa, Matthew R. "FC Receptor-Mediated Activities of Env-Specific Monoclonal Antibodies Generated from Human Volunteers Receiving a DNA Prime-Protein Boost HIV Vaccine: A Dissertation." eScholarship@UMMS, 2010. http://escholarship.umassmed.edu/gsbs_diss/866.

Full text

Abstract:

Human immunodeficiency type 1 (HIV-1) is able to elicit broadly potent neutralizing antibodies in a very small subset of individuals only after several years’ infection and as a result, vaccines that elicit these types of antibodies have been difficult to design. The RV144 trial showed that a moderate protection is possible, which may correlate with antibody dependent cellular cytotoxicity (ADCC) activity. Previous studies in the Lu lab demonstrated that in an HIV-1 vaccine phase I trial, DP6-001, a polyvalent Env DNA prime-protein boost formulation, could elicit potent and broadly reactive, g

APA, Harvard, Vancouver, ISO, and other styles

18

Berrington, Janet Elizabeth. "Haemophilus influenzae type b and tetanus antibody responses in UK infants : effects of the acellular DTPHib combination vaccine, preterm delivery, and a booster dose of PRP-T." Thesis, University of Newcastle upon Tyne, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413255.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Han, Thomas. "Development of a dna vaccine against _streptococcus mutans_: A novel approach to immunization against dental caries." Scholar Commons, 2005. http://scholarcommons.usf.edu/etd/2912.

Full text

Abstract:

Streptococcus mutans is the main causative agent of dental caries, which is a widespread infectious disease. A number of surface molecules are involved in the pathogenicity of this organism, including adherence and aggregation factors. The wall-associated protein A (WapA) of Streptococcus mutans GS-5 was previously demonstrated to be a sucrose-dependent adherence and aggregation factor, and is a larger precursor to extracellular antigen A (AgA), a candidate antigen for a dental caries vaccine.The full-length wapA gene and a C-terminal truncated version agA encoding the AgA were cloned into the

APA, Harvard, Vancouver, ISO, and other styles

20

Oliveira, Thaís Larré. "Vacinas contra leptospirose: potencial imunoprotetor do antígeno OmpL37." Universidade Federal de Pelotas, 2014. http://repositorio.ufpel.edu.br:8080/handle/prefix/3703.

Full text

Abstract:

Submitted by Maria Beatriz Vieira (mbeatriz.vieira@gmail.com) on 2017-08-29T11:52:09Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dissertacao_thais_larre_oliveira.pdf: 616408 bytes, checksum: 404ac55ee19b90246334aac10658a361 (MD5)<br>Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2017-08-29T19:49:36Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dissertacao_thais_larre_oliveira.pdf: 616408 bytes, checksum: 404ac55ee19b90246334aac10658a361 (MD5)<br>Approved for entr

APA, Harvard, Vancouver, ISO, and other styles

21

Philosof, Bar. "A bacterium from the human microbiota as a vaccine vector. Efficient priming of the murine immune system by vaginal delivery of recombinant Streptococcus gordonii." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1216735.

Full text

Abstract:

The ability to prime the immune system against an antigen, and to rapidly recall this response upon antigen reencounter is a fundamental characteristic of the adaptive immune response. The association of an antigen recognized by the immune system in a certain tissue, with the same antigen encountered at a later timepoint in a different tissue, is of primary importance to obtain a systemic and effective immune response and is the foundation behind the utilization of vaccines. The study of vaccine delivery platforms that may activate the immune system in such a manner is therefore of primary imp

APA, Harvard, Vancouver, ISO, and other styles

22

Sevil, Victoria. "Influence of oral boost immunizations with recombinant Salmonella vaccine strains on the antigen-specific CD8 T-cell induction." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-72867.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Espíndola, Milena Sobral. "Avaliação de estratégias de vacinação \"prime-boost\" na infecção experimental por Schistosoma mansoni empregando vacinas de DNA." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/17/17147/tde-02062011-105929/.

Full text

Abstract:

A esquistossomose é uma das mais relevantes doenças induzidas por helmintos, acometendo cerca de 207 milhões de pessoas em todo o mundo. O Praziquantel e o Oxamniquine são os fármacos empregados no tratamento, mas além de não impedirem re-infecções, não atuam nos estágios imaturos do verme. Portanto, o desenvolvimento de uma estratégia de vacinação eficaz representa um componente essencial para o controle e erradicação desta doença. Neste sentido, tivemos como objetivo estudar a resposta imunológica induzida pela imunização com a vacina DNA-Sm14 em associação com a DNA-Hsp65 utilizando protoco

APA, Harvard, Vancouver, ISO, and other styles

24

Figueiredo, Lilybeth de Andrade. "Vacinas, novas perspectivas." Master's thesis, [s.n.], 2014. http://hdl.handle.net/10284/4876.

Full text

Abstract:

Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>As vacinas são uma das maiores descobertas da medicina moderna e têm contribuído para salvar a vida de milhares de milhões de pessoas em cooperação com outras medidas de saúde pública (ao nível do saneamento básico, antibióticos, etc.). As vacinas tiveram um forte impacto no combate a muitas doenças, tendo sido a erradicação da varíola uma das maiores conquistas. No entanto, esta área enfrenta ainda desafios complexos, como são o

APA, Harvard, Vancouver, ISO, and other styles

25

Searle, Benjamin James. "Characterisation of heterologous prime-boost vaccination strategies : an investigation into the nature and delivery of vaccines and the subsequent generation of immune responses." Thesis, University of Glasgow, 2004. http://theses.gla.ac.uk/2779/.

Full text

Abstract:

This thesis describes work undertaken to consider how strategies of vaccination can be manipulated to generate specific types and magnitude of immune response to prevent infection or treat established infection. The vaccination strategies employed were based on the initial delivery of DNA vaccine through intramuscular injection or ballistic delivery using a gene gun, followed by heterologous boosts, based on the same antigen delivered using an alternative route. These boost strategies included a) intramuscular delivery of purified recombinant HBcAg, b) mucosal delivery of HBcAg expressed by an

APA, Harvard, Vancouver, ISO, and other styles

26

Abrahao, Jonatas Santos. "Prevenção e controle do Vaccinia virus no Brasil: padronização de um sistema prime-boost para imunização e determinação de seus hospedeiros naturais." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/BUOS-8PAH8T.

Full text

Abstract:

The Poxviridae family comprises large and complex viruses that infect vertebrates and invertebrates. Orthopoxvirus (OPXV) is a Poxviridae familys genus, and comprises species with clinical and veterinary relevance, like Variola virus, Cowpox virus, 5 Monkeypox Virus and Vaccinia virus (VACV). VACV has been associated with bovine vaccine outbreaks in Brazil, causing ulcerative lesions in cattle and humans, causing economical losses and social impact. Since 1999, several bovine vaccine outbreaks were notified in Brazil, and many strains of VACV were isolated during such outbreaks. There are few

APA, Harvard, Vancouver, ISO, and other styles

27

Prieri, Marion. "Reprogrammation de la bioactivation de prodrogues antituberculeuses : conception, synthèse et évaluation biologique de molécules bioactivables selon différents mécanismes oxydatifs et de composés potentialisant l’activité de nitro-imidazolés." Thesis, Lille, 2018. http://www.theses.fr/2018LILUS056.

Full text

Abstract:

Depuis deux décennies, l’humanité est confrontée à une augmentation spectaculaire du nombre de bactéries résistantes et multirésistantes aux antibiotiques, mettant en péril l’arsenal thérapeutique au complet. La tuberculose est particulièrement concernée par l’apparition de souches multirésistantes aux antibiotiques, obligeant très souvent les médecins à prolonger de plusieurs mois la prise en charge des patients et à jongler avec différents antibiotiques en cours de traitement, ce qui retarde d’autant plus la guérison. En outre, si les souches pan-résistantes restent, pour le moment, exceptio

APA, Harvard, Vancouver, ISO, and other styles

28

Abdul, Fabien. "Développement et évaluation de nouvelles stratégies pour le traitement des hépatites B chroniques, dans le modèle du canard de Pékin infecté par le DHBV." Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10284.

Full text

Abstract:

Développement et évaluation de nouvelles stratégies pour le traitement des hépatites B chroniques, dans le modèle du canard de Pékin infecté par le DHBVL’infection chronique par le HBV est la cause majeure de cirrhose hépatique et de carcinome hépatocellulaire, conduisant à plus d’un million de décès chaque année. Le faible taux de réussite des thérapies actuelles des hépatites B montre la nécessité du recours à des méthodes thérapeutiques alternatives. Ainsi, nous avons étudié une stratégie pertinente reposant sur l’utilisation de molécules antisens (PNAs) couplées à des peptides perméabilisa

APA, Harvard, Vancouver, ISO, and other styles

29

"Searching for an HIV Vaccine: A Heterologous Prime-boost System using Replicating Vaccinia Virus and Plant-produced Virus-like Particles." Doctoral diss., 2016. http://hdl.handle.net/2286/R.I.40210.

Full text

Abstract:

abstract: The HIV-1 pandemic continues to cause millions of new infections and AIDS-related deaths each year, and a majority of these occur in regions of the world with limited access to antiretroviral therapy. Therefore, an HIV-1 vaccine is still desperately needed. The most successful HIV-1 clinical trial to date used a non-replicating canarypox viral vector and protein boosting, yet its modest efficacy left room for improvement. Efforts to derive novel vectors which can be both safe and immunogenic, have spawned a new era of live, viral vectors. One such vaccinia virus vector, NYVAC-KC, was

APA, Harvard, Vancouver, ISO, and other styles

30

Hsieh, Chin-yen, and 謝金燕. "Long-term effect of HBV vaccine booster policy for a certain university students in Southern Taiwan." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/81103259413311163002.

Full text

Abstract:

碩士<br>國立高雄大學<br>運動健康與休閒學系碩士班<br>102<br>Since 1986, the newborns in Taiwan received hepatitis B vaccination, and the prevalence ofhepatitis Bcarriers dropped from 10% to below 1%. In recent years, however, the rate of negative anti-HBs was found over 53% at freshmen’s examination. This search investigates the relation among gender, HBsAg and anti-HBs, and analyzes the effectiveness of hepatitis B vaccination after adding one dose of vaccine. Research Methods: Collecting the physical examination data of 26,108 freshmen in a certain university at southern Taiwan from 2006 to 2012, and analyzes th

APA, Harvard, Vancouver, ISO, and other styles

31

Aviles, Jenna. "Determination of optimal prime-boost vaccination regimens against zaire ebolavirus." 2013. http://hdl.handle.net/1993/22128.

Full text

Abstract:

Zaire ebolavirus is a long filamentous single-stranded RNA virus belonging to the family Filoviridae. Due to the virus’ high mortality rate, lack of an approved vaccine, and potential use as a bioterrorism weapon, research on this topic has been of high demand. To address this issue, several vector platforms have been investigated as vaccine candidates. DNA and adenovirus vaccine platforms are known to elicit robust cellmediated immune responses, while adeno-associated virus and vesicular stomatitis virus vaccines are recognized for strong humoral responses. The leading hypothesis of the

APA, Harvard, Vancouver, ISO, and other styles

32

Estcourt, Marie Joanne. "Studies on the immunobiology of prime-boost immunisation." Phd thesis, 2001. http://hdl.handle.net/1885/146092.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

"Plague vaccine: Homologous and heterologous prime-boost strategies using recombinant Yersinia pestis proteins." Tulane University, 2005.

Find full text

Abstract:

Yersinia pestis has been identified as a potential agent of biological warfare or bioterrorism and presents a particular challenge to vaccine developers because of the severity and potential transmissibility of the pneumonic form of the disease in humans. A Y. pestis-derived fusion protein (F1-V) has shown great promise as a protective antigen in murine studies. Here, initial studies were done to examine the ability of different prime-boost regimens, including parenteral, mucosal, and transcutaneous delivery, to induce a specific immune response of high titer and long duration. Next, we examin

APA, Harvard, Vancouver, ISO, and other styles

34

Wu, Fan. "Evaluation of mucosal T cell immunity following HIV-1 prime-boost immunization." Master's thesis, 2010. http://hdl.handle.net/1885/151293.

Full text

Abstract:

Vaccination is one of the most important contributions to human health and has produced a dramatic reduction in infectious disease deaths over the last 100 years. However, there is still no successful vaccine for HIV-1 that provides full protection against infection. Because HIV-1 primarily infects the mucosae, there is strong opinion that more effective mucosal HIV-1 vaccines eliciting robust immunity at mucosal sites will be a key requirement for a successful vaccine. This thesis evaluates mucosal HIV-specific CD8{u207A} T cell responses following prime-boost immunization with a novel HIV-1

APA, Harvard, Vancouver, ISO, and other styles

35

Lin, Chu Chi, and 林主祈. "Study on the immunogenicity of DNA prime-adenovirus boost immunization of cervical cancer vaccine in the mouse model." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/3drh6m.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Lin, Guan-Cheng, and 林冠丞. "Prime-boost immunization using adenovirus vector and envelope domain III protein fused with flagellin for tetravalent dengue vaccine development." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/85543410575282943124.

Full text

Abstract:

碩士<br>國立清華大學<br>生物科技研究所<br>101<br>A dramatic increase in incidents has been documented indicating that DENV has become a major international health concern. E protein domain III (EDIII) is the receptor binding domain, and was demonstrated that EDIII contains serotype-specific epitopes. In this study, the E.coli-based fusion protein, containing a TLR5 agonist, flagellin (FliC), and EDIII epitopes in a single polypeptide, which could elicit significantly higher neutralizing antibodies than EDIII mixed with FliC. We further evaluated the heterologous prime-boost strategy using adenovirus vector e

APA, Harvard, Vancouver, ISO, and other styles

37

Sevil, Domènech Victòria [Verfasser]. "Influence of oral boost immunizations with recombinant Salmonella vaccine strains on the antigen-specific CD8 T-cell induction / vorgelegt von Victòria Sevil Domènech." 2007. http://d-nb.info/985990163/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!