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Academic literature on the topic 'Botanical food supplement'

Author: Grafiati

Published: 10 March 2023

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Journal articles on the topic "Botanical food supplement"

1

Giammarioli, Stefania, Concetta Boniglia, Brunella Carratù, Marco Ciarrocchi, Flavia Chiarotti, Maurizio Mosca, and Elisabetta Sanzini. "Use of food supplements and determinants of usage in a sample Italian adult population." Public Health Nutrition 16, no. 10 (October 1, 2012): 1768–81. http://dx.doi.org/10.1017/s1368980012004314.

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AbstractObjectiveThe aims were to collect data on consumption of different food supplements in a sample of the adult Italian population and to characterize users by demographic, physical and health-related characteristics, lifestyle and behaviour.DesignCross-sectional survey.SettingThe study was conducted in 2008 in ten towns of Italy (two towns from each of the five macro-areas: Northwest, Northeast, Centre, South and Islands).SubjectsAdults (n10 000) aged ≥18 years were randomly selected and asked to fill in a self-administered questionnaire regarding their use of food supplements and the above variables. The effect of these variables on food supplement use was evaluated by univariate and multivariate logistic regression.ResultsOf the 1723 individuals who returned the questionnaire, 49 % were users of food supplements. A large proportion (54 %) of users used more than one category of food supplement: vitamin and/or mineral supplements were the most used (61 %), followed by supplements with botanicals and botanical extracts (28 %). The results obtained by logistic regression showed that gender, town size, education level, sports practice, regular use of wholemeal cereal-based foods and presence of a low stress level were determinants for the use of food supplements in the examined population. However, these determinants were not shared by all categories of supplements.ConclusionsThe results of this preliminary study highlight that associations between demographic, dietary and lifestyle factors and use of different categories of food supplements differ according to products, and cannot be accounted for simply by dichotomizing individuals as users or non-users.

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Albadry, Mohamed A., and Ikhlas A. Khan. "Roadmap for Quality by Design Implementation for Dietary Supplements." Journal of AOAC INTERNATIONAL 103, no. 1 (January 1, 2020): 103–16. http://dx.doi.org/10.5740/jaoacint.18-0415.

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Abstract Background: Recently, there is a growing interest in quality by design (QbD) in the dietary supplements industry. Objective: Effective QbD implementation necessitates a comprehensive understanding of multiple factors such as; the relationship between the critical qualities attributes (CQAs) and the scientific properties of the dietary supplement, the relationship between the manufacturing process, CQAs and the variability in raw materials. There are still two critical challenging concerns to be addressed in the implementation of QbD for herbal drugs. First, the quality variation of botanical raw materials and second, the difficulty in defining the satisfactory ranges of CQAs. Method: In order to tackle these challenges, this review provides a snapshot of the numerous techniques that can be used in the identification and characterization of the botanical raw materials, therefore, will help in the successful QbD implementation for botanicals and dietary supplements. Conclusions: In order to implement this approach and to be considered in the current dietary supplement regulations, fruitful discussions and collaborations between academia, industry and regulatory agencies are required.

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Bilia, Anna Rita. "Herbal Medicinal Products versus Botanical-Food Supplements in the European market: State of Art and Perspectives." Natural Product Communications 10, no. 1 (January 2015): 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000130.

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Botanical products marketed in Europe are diverse, classified as herbal medicinal products, dietary supplements, cosmetics, foods and beverages depending on the relevant applicable legislation. Many factors are taken into account in the classification of a botanical product (e.g. intended use, labeling, preparations and dosages) according to how it is placed on the market. Herbal medicinal products (HMPs) can only be sold in pharmacies, under the supervision of a pharmacist, and are marketed after full or simplified registration procedures according to their classification, i.e. as over-the-counter drugs (OTC) available without special restrictions and prescription only medicine (POM), which must be prescribed by a licensed medical practitioner. The dietary supplement segment is also sold in the market in dose form (such as capsules, tablets, ampoules of liquids, drops etc) and represents 15-20% of the botanical market at the European level with high variability among each country (i.e. in Italy it reaches up to 80%). In many cases the distinction between medicinal products and food supplements has generated borderline botanical-sourced products, which generally produce confusion and mislead the consumers. As a consequence, there is an urgent need of consumer education and in addition to collect comprehensive data and make this database systematically available to herbalists, nutritionists and medical specialists for a proper classification and harmonization of the use of botanical ingredients, and, as consequence, a correct use of these products.

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Grippo, Anne A., Kayla Capps, Ben Rougeau, and Bill J. Gurley. "Analysis of Flavonoid Phytoestrogens in Botanical and Ephedra-Containing Dietary Supplements." Annals of Pharmacotherapy 41, no. 9 (September 2007): 1375–82. http://dx.doi.org/10.1345/aph.1h497.

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Background: Plant-derived botanical and dietary supplements are widely self-prescribed in the US and considered natural, safe, and beneficial. However, because they are not strictly regulated by the Food and Drug Administration (FDA), their ingredients are not always known and they may contain unexpected agents. Among the myriad plant-produced molecules are flavonoids, which reportedly have various human health effects, including anticancer, antioxidant, and estrogenic properties. Several flavonoids (eg, isoflavones) are known as phytoestrogens, based on their ability to mimic estrogen in mammals. Because botanical and dietary supplements are plant products and need not be processed or purified due to their FDA classification as foods, they may contain unexpected phytoestrogens, such as flavonoids. Objective: To analyze 8 botanical and 11 ephedra-containing dietary supplements for the presence and concentration of 5 flavonoids (biochanin A, daidzein, formononetin, genistein, quercetin), which may deliver unexpected estrogenic activity. Method: Randomly selected tablets from single bottles of 19 botanical and dietary supplements purchased locally were pooled. Flavonoids were extracted into ethanolic solution and analyzed by high-performance liquid chromatography. Results: Flavonoids were detected in all supplements tested, with the largest number (4) found in Kava Kava. Almost all supplements contained measurable amounts of genistein and/or daidzein, known estrogenic agents, at up to 22 mg/day of isoflavone, per recommended daily dosage of supplement. Conclusions: These results suggest that single-component botanical and multi-ingredient dietary supplements could contain unexpected estrogenic agents, which may impact the health of consumers.

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S., Nushusna, Yumi Zuhanis H.Y.H., and Hamzah M.S. "In-silico approach in risk assessment of nutraceutical properties." Food Research 4, S1 (February 10, 2020): 28–33. http://dx.doi.org/10.26656/fr.2017.4(s1).s35.

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Dietary supplements, including those containing botanical ingredients and botanicalderived compounds, have been marketed to consumers globally for many decades. However, the legislative framework for such products remains inconsistent across jurisdictions internationally. A common problem, concerning these nutraceutical products, is deficient information and lack of data for assessing the hazards posed to human health. The main objective is to explore the use of in silico tools in a risk assessment context of nutraceutical product, to relate properties of the molecular structure to the toxic effect of the chemical substance, by using principles and methods of computational chemistry. Further consideration of the actual impact of adverse events arising from nutraceutical food supplement usage will be helpful in guiding such issue as a potential for misidentification, and adulteration of botanical supplements by pharmacologically active substances.

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Ang, Catharina Y. W., Yanyan Cui, Hebron C. Chang, Wenhong Luo, Thomas M. Heinze, Lawrence J. Lin, and Antonia Mattia. "Determination of St. John's Wort Components in Dietary Supplements and Functional Foods by Liquid Chromatography." Journal of AOAC INTERNATIONAL 85, no. 6 (November 1, 2002): 1360–69. http://dx.doi.org/10.1093/jaoac/85.6.1360.

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Abstract St. John's wort ( Hypericum perforatum L.) preparations, a top-selling botanical dietary supplement used primarily as an antidepressant, has recently been used as an ingredient in some food products sold as functional foods. A rapid extraction technique followed by a liquid chromatographic (LC) method was developed to determine 4 characteristic bioactive compounds (pseudohypericin, hypericin, hyperforin, and adhyperforin) from St. John's wort in dietary supplements and functional foods to which it was added. Solid samples, including including dried leaf/flower mixture, dietary supplement capsules, tea bags, puff and snack bar, were extracted with methanol by sonication.Noncarbonated, fruit-flavored drinks were centrifuged and mixed with methanol. Compounds were then determined by isocratic, reversed-phase LC with UV detection at 2 wavelengths and further identified or confirmed by photodiode array spectra and LC/mass spectrometry. Within-laboratory method variations (% RSD) were satisfactory. Very low amounts, if any, of the 4 components were found in drink and puff samples, and none was found in the snack bar. The methods developed provide a useful means for the determination of St. John's wort components in dietary supplements and functional foods.

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Nobile, Vincenzo, Enza Cestone, Francesco Puoci, Ileana Deponti, Marta Pisati, and Angela Michelotti. "In Vitro and In Vivo Study on Humans of Natural Compound Synergy as a Multifunctional Approach to Cellulite-Derived Skin Imperfections." Cosmetics 7, no. 2 (June 16, 2020): 48. http://dx.doi.org/10.3390/cosmetics7020048.

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Aim: The present study aimed to assess the efficacy of a nutraceutical ingredient, SelectSIEVE® Rainbow, based on botanical extracts, in ameliorating cellulite-derived skin imperfections and microcirculation. The nutritional supplement contained a mixture of Oryza sativa (L.), Citrus sinensis (L.) Osbeck, Ananas comosus (L.) Merr, and Actinidia chinensis Planch; all ingredients were botanicals that can be used in food supplements. Results: In vitro studies showed the high capacity of the supplement to have an anti-inflammatory, antioxidant, and hypolipidemic effect, accompanied by an interesting proteolytic activity. The randomized double-blind placebo-controlled clinical trial, carried out on 60 women during an 8-week treatment period, confirmed the in vitro study results. SelectSIEVE® Rainbow showed a whole-body shaping activity, with a reduction of the waist, hip, and tight circumference of 0.8, 0.65 and 0.72 cm, respectively. It also showed a reduction of subcutaneous fat mass of 1.24 mm and body weight, with an average of 0.7 kg and positive peaks of −2.9 kg. Skin health and appearance were also improved: +5.4% skin elasticity, +5.5% skin tonicity and +5.7% skin draining. Finally, the dermatological evaluation of the cellulite score and microcirculation showed an improvement in 57% and 60% of the subjects enrolled in the studies. Conclusions: This first study provides interesting inputs on the effectiveness of the nutraceutical complex standardized in polyphenols, anthocyanins and proteolytic enzymes to counteract cellulite blemishes and improve local microcirculation. The positive response encourages deeper studies and further investigation.

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Hunter, Elizabeth Sage, Robert Literman, and Sara M. Handy. "Utilizing Big Data to Identify Tiny Toxic Components: Digitalis." Foods 10, no. 8 (August 3, 2021): 1794. http://dx.doi.org/10.3390/foods10081794.

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The botanical genus Digitalis is equal parts colorful, toxic, and medicinal, and its bioactive compounds have a long history of therapeutic use. However, with an extremely narrow therapeutic range, even trace amounts of Digitalis can cause adverse effects. Using chemical methods, the United States Food and Drug Administration traced a 1997 case of Digitalis toxicity to a shipment of Plantago (a common ingredient in dietary supplements marketed to improve digestion) contaminated with Digitalis lanata. With increased accessibility to next generation sequencing technology, here we ask whether this case could have been cracked rapidly using shallow genome sequencing strategies (e.g., genome skims). Using a modified implementation of the Site Identification from Short Read Sequences (SISRS) bioinformatics pipeline with whole-genome sequence data, we generated over 2 M genus-level single nucleotide polymorphisms in addition to species-informative single nucleotide polymorphisms. We simulated dietary supplement contamination by spiking low quantities (0–10%) of Digitalis whole-genome sequence data into a background of commonly used ingredients in products marketed for “digestive cleansing” and reliably detected Digitalis at the genus level while also discriminating between Digitalis species. This work serves as a roadmap for the development of novel DNA-based assays to quickly and reliably detect the presence of toxic species such as Digitalis in food products or dietary supplements using genomic methods and highlights the power of harnessing the entire genome to identify botanical species.

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Kamiński, Mikołaj, Matylda Kręgielska-Narożna, and Paweł Bogdański. "Determination of the Popularity of Dietary Supplements Using Google Search Rankings." Nutrients 12, no. 4 (March 26, 2020): 908. http://dx.doi.org/10.3390/nu12040908.

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The internet provides access to information about dietary supplements and allows their easy purchase. We aimed to rank the interest of Google users in dietary supplements and to determine the changes that occurred in their popularity from 2004 to 2019. We used Google Trends to generate data over time on regional interest in dietary supplements (n = 200). We categorized each included supplement and calculated the interest in all topics in proportion to the relative search volume (RSV) of “lutein”. We analyzed the trends over time of all topics and categories. Globally, the topics with the highest popularity were “magnesium”, which was 23.72 times more popular than “lutein”, “protein” (15.22 times more popular), and “iron” (15.12). The categories of supplements receiving most interest were protein (9.64), mineral (5.24), and vitamin (3.47). The RSV of seven categories of topics (amino acid, bacterial, botanical, fiber, mineral, protein, and vitamin) increased over time while two categories (enzyme and fat or fatty acid) saw a drop in their RSV. Overall, 119 topics saw an increase in interest over time, 19 remained stable, and 62 saw interest in them decrease. Google Trends provides insights into e-discourse and enables analysis of the differences in popularity of certain topics across countries and over time.

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Boullata, Joseph I., Patrick J. McDonnell, and Cynthia D. Oliva. "Anaphylactic Reaction to a Dietary Supplement Containing Willow Bark." Annals of Pharmacotherapy 37, no. 6 (June 2003): 832–35. http://dx.doi.org/10.1345/aph.1d027.

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OBJECTIVE: To report a case of anaphylaxis resulting from the use of a willow bark–containing dietary supplement in a patient with a history of an aspirin allergy. CASE SUMMARY: A 25-year-old white woman presented to the emergency department of a community teaching hospital with anaphylaxis requiring epinephrine, diphenhydramine, methylprednisolone, and volume resuscitation to which she responded favorably. Medication history revealed that she had ingested 2 capsules of Stacker 2 (NVE Pharmaceuticals, Newton, NJ), a dietary supplement promoted for weight loss, prior to experiencing her initial symptoms. Among other active ingredients, this product contains willow bark. Of significance is that this patient also reported a history of allergy to acetylsalicylic acid. No other causes for anaphylaxis were identified. She continued to receive routine supportive care and the remaining hospital course was uncomplicated. DISCUSSION: Dietary supplements, including herbal products, are used by many individuals who consider them to be inherently safe despite limited regulatory oversight by the Food and Drug Administration. While there may be value to specific botanical ingredients, a potential for adverse effects also exists. The popular product consumed by our patient is used for weight loss and contains willow bark, a source of salicylates. Based on the Naranjo probability scale, it is probable that this case of anaphylaxis was due to this dietary supplement. CONCLUSIONS: The use of any willow bark–containing dietary supplement may present a risk of anaphylactic reaction to patients with a history of allergy to salicylates. Clinicians need to recognize the potential for adverse effects from dietary supplements.

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Books on the topic "Botanical food supplement"

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Restani, Patrizia, ed. Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-62229-3.

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(Firm), Find/SVP. The market for nutraceuticals. New York, N.Y: FIND/SVP, 1998.

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Guidance for the Safety Assessment of Botanicals And Botanical Preparations for Use in Foods And Food Supplements. Intl Life Sciences Inst, 2003.

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Restani, Patrizia. Food Supplements Containing Botanicals : Benefits, Side Effects and Regulatory Aspects: The Scientific Inheritance of the EU Project PlantLIBRA. Springer, 2017.

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Restani, Patrizia. Food Supplements Containing Botanicals : Benefits, Side Effects and Regulatory Aspects: The Scientific Inheritance of the EU Project PlantLIBRA. Springer, 2018.

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6

Durazzo, Alessandra, Massimo Lucarini, and Michael Heinrich, eds. Dietary Supplements, Botanicals and Herbs at The Interface of Food and Medicine. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-654-3.

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Nutrition and Cancer Prevention: New Insights into the Role of Phytochemicals. Springer Verlag, 2013.

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Book chapters on the topic "Botanical food supplement"

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Carratù, Brunella, and Stefania Giammarioli. "Food Supplements Containing Botanicals: The Concept of Quality." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 179–95. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_6.

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Trovato, Marinella, and Cinzia Ballabio. "Botanical Products: General Aspects." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 3–26. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_1.

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Garcia-Alvarez, Alicia, Blanca Roman-Viñas, Liliana Vargas-Murga, Lourdes Ribas-Barba, and Lluis Serra-Majem. "Assessment of Food Supplements Containing Botanicals in Epidemiological Research." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 61–115. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_3.

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Boniglia, Concetta, Brunella Carratù, Raffaella Gargiulo, and Emanuela Bortolin. "Detection of Irradiated Herbal Ingredients of Plant Food Supplements by Thermoluminescence Technique." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 395–407. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_13.

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Egan, Bernadette, Flavia Bruno, Mihaela Badea, Matthew Peacock, Martina Laccisaglia, Lorena Dima, and Monique M. Raats. "Consumers’ Understanding of Plant Food Supplements: Benefits, Risks and Sources of Influence." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 437–58. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_15.

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Badea, Mihaela, Concetta Boniglia, Brunella Carratù, Remigius Chizzola, Chlodwig Franz, Stefania Giammarioli, Maurizio Mosca, Johannes Novak, Paul A. Steenkamp, and Patrizia Restani. "Protocols for Developing and Testing Methods Applied to the Quality Control of Botanicals." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 197–208. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_7.

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Steenkamp, Paul A., Lucia H. Steenkamp, and Dalu T. Mancama. "Profiling of Botanical Extracts for Authentication, Detection of Adulteration and Quality Control Using UPLC-QTOF-MS." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 303–47. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_10.

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Badea, Mihaela, Laura Floroian, Angela Marculescu, Liviu Gaceu, Marius Moga, Laura Gaman, Codruta Cobzac, Qi Chang, Jian Xue, and Patrizia Restani. "Classic/Recommended Methods and Development of new Methods to Control Residues and Contaminants of Botanicals." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 349–78. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_11.

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Di Lorenzo, Chiara, Francesca Colombo, Francesca Orgiu, Gianfranco Frigerio, Donatella Caruso, and Patrizia Restani. "Classic/Recommended Methods and Development of new Methods to Control Adulteration and Counterfeits." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 379–94. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_12.

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Guzzon, Antonella, and Luca Bucchini. "Risk and Benefit Assessment: Methodologies and Scientific Acceptance." In Food Supplements Containing Botanicals: Benefits, Side Effects and Regulatory Aspects, 411–35. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62229-3_14.

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