Relevant bibliographies by topics / Brachytherapy

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Academic literature on the topic 'Brachytherapy'

Author: Grafiati
Published: 4 June 2021
Last updated: 14 September 2024

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Journal articles on the topic "Brachytherapy"

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Marosevic, Goran, Dzenita Ljuca, Hasan Osmic, Semir Fazlic, Oliver Arsovski, and Dusan Mileusnic. "Inter-application displacement of brachytherapy dose received by the bladder and rectum of the patients with inoperable cervical cancer." Radiology and Oncology 48, no. 2 (June 1, 2014): 203–9. http://dx.doi.org/10.2478/raon-2013-0082.

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AbstractBackground. The aim of the study was to examine on the CT basis the inter-application displacement of the positions D0.1cc, D1ccand D2ccof the brachytherapy dose applied to the bladder and rectum of the patients with inoperable cervical cancer.Patients and methods. This prospective study included 30 patients with cervical cancer who were treated by concomitant chemo-radiotherapy. HDR intracavitary brachytherapy was made by the applicators type Fletcher tandem and ovoids. For each brachytherapy application the position D0.1ccwas determined of the bladder and rectum that receive a brachytherapty dose. Then, based on the X, Y, and Z axis displacement, inter-application mean X, Y, and Z axis displacements were calculated as well as their displacement vectors (R). It has been analyzed whether there is statistically significant difference in inter-application displacement of the position of the brachytherapy dose D0.1cc, D1ccand D2ccof the bladder and rectum. The ANOVA test and post-hoc analysis by Tukey method were used for testing statistical importance of differences among the groups analyzed. The difference among the groups analyzed was considered significant if p < 0.05. Results. There are significant inter-application displacements of the position of the brachytherapy dose D0,1cc, D1ccand D2ccof the bladder and rectum. Conclusions. When we calculate the cumulative brachytherapy dose by summing up D0,1cc, D1ccand D2ccof the organs at risk for all the applications, we must bear in mind their inter-application displacement, and the fact that it is less likely that the worst scenario would indeed happen
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Tanimoto, Ryuta, Kensuke Bekku, Yasuyuki Kobayashi, Shin Ebara, Motoo Araki, Norihisa Katayama, Yasutomo Nasu, and Hiromi Kumon. "Predictive factors for acute and late urinary toxicities after permanent prostate brachytherapy." Journal of Clinical Oncology 30, no. 5_suppl (February 10, 2012): 90. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.90.

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90 Background: To describe the frequency of acute and late Radiation Therapy Oncology Group (RTOG) urinary toxicity associated with predictive factors and International Prostate Symptom Score (IPSS) in consecutive prostate brachytherapy patients. Methods: From January 2004 to April 2011, 466 patients underwent permanent 125I-seed brachytherapy (median follow-up, 48 months). The IPSS and RTOG toxicity data were prospectively collected. The prostate volume, IPSS before and after brachytherapy and postimplant analysis were examined for an association with urinary toxicity which was defined as urinary RTOG toxicity 1 or more. Logistic regression analysis was used to examine the factors associated with urinary toxicities. Results: The rate of RTOG urinary toxicity Grade 1 or more at 1, 6, 12, 24, 36, 48 months was 67%, 40%, 21%, 31%, 27%, 28%, respectively. Grade 2 or more urinary toxicities were less than 1% at an each point. IPSS was highest at 3 months and returned to normal level at 12 months after brachytherpapy. On univariate analysis, patients with larger prostate size, greater baseline IPSS, the higher post V100 (volume of the prostate covered by 100% of the dose), higher post V150 and higher post D90 (dose that 90% of the target volume received) had more acute urinary toxicities 1 month as well as 12 months after brachytherapy. On multivariate analysis, the significant predictors for urinary toxicities were a greater baseline IPSS and post V100 one month as well as 12 months after brachytherapy (shown below). Conclusions: Most urinary symptoms were tolerated and resolved within 12 months after prostate brachytherapy. Acute and late urinary toxicities after brachytherapy were strongly related with baseline IPSS and the post V100.
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Maj-Dziedzic, Monika, Anna Brzozowska, Marcelina Sikora, Marta Zarzycka, Ines Plewniok, Jeremiasz Dubiel, Adrian Maj, Greta Śmietana, Martyna Warno, and Wiktor Kozik. "Brachytherapy in Breast Cancer Treatment: Physical and Biological Aspects." Journal of Education, Health and Sport 62 (February 22, 2024): 164–71. http://dx.doi.org/10.12775/jehs.2024.62.011.

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This scientific paper focuses on the treatment of breast cancer, one of the most common cancers among women. Despite increased awareness and the popularity of screening tests, statistics indicate a significant rise in incidence. The paper presents breast-conserving treatment methods, including brachytherapy, as a modern technique with promising outcomes. It describes the physical properties of ionizing radiation used in brachytherapy, discussing the photoelectric effect, Compton effect, and the phenomenon of pair production. The paper then delves into the biological effects of ionizing radiation, emphasizing the dependence on the cell cycle phase. It highlights lethal, sublethal, and potentially lethal cellular damage, categorizing the effects of radiation interaction into early and late responses. The discussion transitions to the application of brachytherapy in breast cancer treatment, focusing on various techniques such as LDR, PDR, and HDR. The paper provides a detailed description of brachytherapy's use in breast-conserving treatment, considering contraindications, treatment planning, and Accelerated Partial Breast Irradiation (APBI) techniques. The radioisotopes used in brachytherapy are also presented, with special attention to Iridium-192. The physical and practical aspects related to this isotope are discussed, along with other commonly used radioisotopes such as Cesium-137, Cobalt-60, and Strontium-90. The paper concludes with a summary, emphasizing the significance of brachytherapy in breast cancer treatment and outlining its prospects for development. The authors highlight precision and shortened therapy duration.
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Leskinen, Sandra, Netanel Ben-Shalom, Jason Ellis, David Langer, John A. Boockvar, Randy S. D’Amico, and A. Gabriella Wernicke. "Brachytherapy in Brain Metastasis Treatment: A Scoping Review of Advances in Techniques and Clinical Outcomes." Cancers 16, no. 15 (July 31, 2024): 2723. http://dx.doi.org/10.3390/cancers16152723.

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Brain metastases pose a significant therapeutic challenge in the field of oncology, necessitating treatments that effectively control disease progression while preserving neurological and cognitive functions. Among various interventions, brachytherapy, which involves the direct placement of radioactive sources into or near tumors or into the resected cavity, can play an important role in treatment. Current literature describes brachytherapy’s capacity to deliver targeted, high-dose radiation while minimizing damage to adjacent healthy tissues—a crucial consideration in the choice of treatment modality. Furthermore, advancements in implantation techniques as well as in the development of different isotopes have expanded its efficacy and safety profile. This review delineates the contemporary applications of brachytherapy in managing brain metastases, examining its advantages, constraints, and associated clinical outcomes, and provides a comprehensive understanding of advances in the use of brachytherapy for brain metastasis treatment, with implications for improved patient outcomes and enhanced quality of life.
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Petera, Jiri, Renata Neumanová, Karel Odrazka, Martin Ondrak, and Egon Prochazka. "Perioperative Hyperfractionated High-Dose Rate Brachytherapy Combined with External Beam Radiotherapy in the Treatment of Soft Tissue Sarcomas." Tumori Journal 91, no. 4 (July 2005): 331–34. http://dx.doi.org/10.1177/030089160509100409.

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Aims and background Low-dose rate brachytherapy alone or in combination with external beam radiotherapy represents a well-established adjuvant treatment in soft tissue sarcomas following surgical resection. The experience with high-dose radiotherapy in this indication is limited. The purpose of our study was an evaluation of the viability of perioperative hyperfractionated high-dose rate brachytherapy in combination with external beam radiotherapy for primary and recurrent soft tissue sarcomas. Patients and methods From February 1998 through June 2002, 10 adult patients with soft tissue sarcomas were treated by interstitial perioperative high-dose rate brachytherapy and external beam radiotherapy. TNM classification was pT2bpN0pM0 in 9 patients and pT1bpN0pM0 in 1 patient. Grade of differentiation was G1 (2 patients), G2 (n = 1), G3 (n = 5), G4 (n = 2). Surgical margins were negative in 7 cases, close in 2 cases and positive in 1 case. The tumor was localized in an extremity in all cases. Hyperfractionation 3 Gy twice daily at 10 mm from the plane of sources was used for brachytherapy, with total doses 18–30 Gy. The patients received external beam radiotheapy with doses 40–50 Gy after brachytherhapy. Follow-up periods were between 24–71 months (median, 46). Results Local control of the disease was achieved in all 10 patients. Distant metastases occurred in 2 cases. One patient was disease free after salvage surgery and chemotherapy, and one patient died of lung disease progression 14 months after brachytherapy. In one case, subcutaneous fistula occurred after radiotherapy and was cured by an excision. Six patients experienced grade 1 or 2 fibrosis and 1 case a mild peripheral neuropathy was recorded. Conclusions Our study on a small number of patients suggests that perioperative hyperfractionated high-dose rate brachytherapy with doses 8 × 3 Gy in combination with external beam radiotherapy 40–50 Gy is a promising method to achieve high biological doses in the postoperative radiotherapy of soft tissue sarcomas without severe late morbidity and warrants further research.
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Pons-Llanas, Olga, Rosa Ballester-Sánchez, Francisco Javier Celada-Álvarez, Cristian Candela-Juan, Teresa García-Martínez, Margarita Llavador-Ros, Rafael Botella-Estrada, et al. "Clinical implementation of a new electronic brachytherapy system for skin brachytherapy." Journal of Contemporary Brachytherapy 4 (2014): 417–23. http://dx.doi.org/10.5114/jcb.2014.47996.

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Shao, Tianchi. "Clinical progress of brachytherapy for cervical cancer." BIO Web of Conferences 111 (2024): 02019. http://dx.doi.org/10.1051/bioconf/202411102019.

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Cervical cancer is a prevalent malignant tumour of the female reproductive system, posing a significant threat to women's health and lives in China. Brachytherapy is a crucial component of radiotherapy for patients with locally intermediate and advanced cervical cancer. This includes intracavitary brachytherapy, interstitial brachytherapy, intracavitary and interstitial combined brachytherapy, and radioactive seed implantation brachytherapy. The aim of this article is to provide an update on the use of intracavitary brachytherapy, interstitial brachytherapy, and radioactive particle implantation.
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Murofushi, Keiko, Yasuo Yoshioka, Minako Sumi, Hitoshi Ishikawa, Masahiko Oguchi, and Hideyuki Sakurai. "Outcomes analysis of pre-brachytherapy MRI in patients with locally advanced cervical cancer." International Journal of Gynecologic Cancer 30, no. 4 (March 11, 2020): 473–79. http://dx.doi.org/10.1136/ijgc-2019-000925.

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IntroductionVarious brachytherapy options are available for treating cervical cancer. This study investigated whether pre-brachytherapy magnetic resonance imaging (MRI) findings could help identify the appropriate brachytherapy technique for cervical cancer.MethodsWe retrospectively evaluated patients with cervical cancer who underwent pre-brachytherapy MRI within 7 days before their first high-dose rate brachytherapy treatment between December 2009 and September 2015. Patients who could not undergo MRI at pre-treatment and/or pre-brachytherapy and complete radical radiotherapy were excluded. Conventional intracavitary brachytherapy was the preferred treatment for ≤4 cm and symmetrical tumors. Non-conventional intracavitary brachytherapy, including interstitial brachytherapy, was the preferred treatment for bulky tumors, asymmetrical tumors, tumors with severe vaginal invasion, or bulky barrel-shaped tumors. The 3-year rates of overall survival, disease-free survival, and local control were compared using the Kaplan–Meier method and the log-rank test. Overall survival and local control rates were assessed using Cox regression analysis to identify risk factors for poor overall survival and local control outcomes.ResultsA total of 146 patients were included in the study. The median tumor sizes were 52 mm (range 17–85) at the pre-treatment MRI and 30 mm (range 0–78) at the pre-brachytherapy MRI. Six patients had International Federation of Gynecology and Obstetrics (FIGO) stage IB2, 67 patients had stage II, 64 patients had stage III, and nine patients had stage IVA disease. A total of 124 (85%) patients had squamous cell carcinoma and 22 (15%) patients had adenosquamous cell carcinoma or adenocarcinoma. The MRI findings showed severe vaginal invasion (pre-treatment: 19 patients, pre-brachytherapy: 10 patients), asymmetrical bulky tumors (pre-treatment: 28 patients, pre-brachytherapy: 16 patients), and severe corpus invasion (pre-treatment: 39 patients, pre-brachytherapy: 18 patients). Based on the pre-brachytherapy MRI findings, non-conventional intracavitary brachytherapy was administered to 34 (23.3%) patients. Brachytherapy seemed to be appropriate for 133 (91.1%) patients and inappropriate for 13 (8.9%) patients. The 3-year rates were 84.2% for overall survival and 90.1% for local control. Grade 3 late rectal complications occurred in two (1%) patients. Multivariate analysis showed that tumor characteristics (size, shape, and extent of invasion) were not risk factors, although inappropriate brachytherapy was significantly related to poor local control (p<0.001).ConclusionPre-brachytherapy MRI may help to select appropriate brachytherapy for cervical cancer and reduce the likelihood of inappropriate brachytherapy leading to poor local control.
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Kubicek, G. J., G. J. Kubicek, S. Brown, and S. Redfield. "Combined brachytherapy and external beam radiation for prostate cancer in a community setting." Journal of Clinical Oncology 27, no. 15_suppl (May 20, 2009): e16147-e16147. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e16147.

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e16147 Background: Prostate cancer is the most common male malignancy, and there is no one standard treatment modality. One treatment option is the combination of external beam radiotherapy and permanent transperineal brachytherapy seed implant Methods: Retrospective review of prostate cancer and side effect outcomes at a single institution in the community setting. All patients were treated with a combination of low dose rate transperineal brachytherapy seed placement and external beam radiation. Results: A total of 897 patients were analyzed, 781 had a minimum follow-up of one year. Median pre-treatment PSA was 8.1 (range 0.3 to 106) and the median Gleason score was 6. With a median follow-up of 3.6 years, 33 (3.4 %) patients had biochemical failure based on the phoenix definition of Nadir + 2. Not including impotence, acute toxicity greater than or equal to Grade 2 was seen in 115 patients (102 GU and 13 GI) and 193 patients had late toxicity greater than or equal to Grade 2 (155 GU and 38 GI). 563 patients received hormone therapy prior to or concurrent with the radiation. Conclusions: This is the largest series reporting on the outcome of combination brachytherpay implant and external beam radiation in the treatment of prostate cancer. Combination treatment using brachytherapy and external beam radiation is well tolerated, with a low rate of biochemical failure and should be considered one of the treatment options for prostate cancer. No significant financial relationships to disclose.
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Bansal, Indu, Debashis Panda, Arun Rathi, Anil Anand, and Anil Bansal. "Rationale, indications, techniques and applications of interstitial brachytherapy for carcinoma cervix." Asian Journal of Oncology 02, no. 02 (July 2016): 069–78. http://dx.doi.org/10.4103/2454-6798.197374.

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AbstractWith evolution of different newer radiotherapy techniques, still the role of brachytherapy in different gynecological malignancies has not sublimed. Most commonly used form of brachytherapy in carcinoma cervix patients is intracavitary brachytherapy. However, all the patients do not qualify for the treatment with intracavitary brachytherapy due to certain clinicopathological conditions. This warrants use of interstitial brachytherapy technique for treatment. For getting good results from interstitial brachytherapy, a good expertise and a proper infrastructure are needed. For perineal interstitial brachytherapy, different templates have been designed, used, and published by authors in different literature over the period. Among all these different templates, Martinez Universal Perineal Interstitial Template (MUPIT) has been used in gynecological, urological, and anorectal malignancies. In this literature review, we have discussed mainly MUPIT.
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Dissertations / Theses on the topic "Brachytherapy"

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Wirth, Manfred P., and Oliver W. Hakenberg. "Brachytherapy for Prostate Cancer." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-133901.

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Melhus, Christopher S. (Christopher Scott) 1974. "Advanced brachytherapy dosimetric considerations." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43808.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2008.
Includes bibliographical references (p. 131-139).
The practice of brachytherapy and brachytherapy dosimetry was investigated with emphasis on evaluations of dose distributions and shielding considerations for both photon- and neutron-emitting radionuclides. Monte Carlo simulation methods were employed to calculate dose distributions for virtual and commercial brachytherapy sources. Radionuclides studied were 103Pd, 1251, 131Cs, 137Cs, 169b, 192Ir, and 252Cf. 252Cf sources also emit neutrons from spontaneous fission. The brachytherapy dosimetry protocol recommended by the American Association of Physicists in Medicine was followed and evaluated for conditions of partial scatter (non-infinite media) and material inhomogeneities, both commonly encountered in brachytherapy treatment. Furthermore, energy-dependent characteristics of dosimetry parameters were evaluated and reference calculations performed for virtual photon and neutron sources. These findings were applied to three clinical brachytherapy cases: eye plaques using 103Pd, 125I, and 131Cs; high-dose rate 252Cf treatment; and, 2 Cf plaques for superficial lesions. For eye plaques, material heterogeneities were significant for each radionuclide with dose reduction at 5 mm of 18%, 11%, and 10% for P03pd, 125I, and 131Cs, respectively. For a proposed highdose rate 252Cf source (5mm length), relative brachytherapy dosimetry parameters were found to be similar to those obtained for a low-dose rate Applicator Tube-type source (15 mm length). Considering 252Cf plaque brachytherapy when partial scatter conditions were accounted for, central axis equivalent dose rate decreased by 11 ± 1% and 7 ± 2% for depths of 4 to 50 mm, respectively.
(cont.) The ratio of neutron dose to total physical dose was 70 ± 1% and 57 ± 2% for depths of 4 and 50 mm, respectively, while the fractional dose-equivalent due to neutrons was 93 + 1% and 89 ± 2% at these depths, respectively. Finally, shielding requirements for a clinical high-dose rate 252Cf source were explored for common shielding materials and a linear accelerator vault. Lead, polyethylene, and borated polyethylene were evaluated for neutron, primary photon, and secondary photon attenuation. Half-value layers of 0.70, 0.15, and 0.13 m were obtained for lead, polyethylene, and borated polyethylene, respectively. A linear accelerator vault was found to adequately shield up to a 5 mg 252Cf source for regular clinical use.
by Christopher S. Melhus.
Ph.D.
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Wirth, Manfred P., and Oliver W. Hakenberg. "Brachytherapy for Prostate Cancer." Karger, 1999. https://tud.qucosa.de/id/qucosa%3A27547.

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Pan, Leo Lijia. "Photoacoustic imaging for prostate brachytherapy." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/48478.

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Photoacoustic (PA) imaging is an emerging imaging modality that relies on the PA effect. The PA effect is caused by exposing an optically absorbing sample to near-infrared light which causes the sample to experience a temporary temperature increase through optical absorption. The heated region undergoes thermoelastic expansion and produces an abrupt and localized pressure change. This change results in a transient PA wave that propagates out toward the sample surface for collection by an ultrasound (US) transducer. Through image reconstruction, the optical property of the sample can be obtained. PA imaging is promising in detecting brachytherapy seeds during prostate brachytherapy. The high absorption coefficient of the metallic seeds leads to high PA imaging contrast. One major drawback is the limited imaging depth due to high optical attenuation of the excitation light in tissue. One of the goals of this thesis is to conduct initial feasibility tests of enhancing the PA contrast through brachytherapy seeds modifications. Seed coated with a contrast enhancing material shows an increase of 18 dB in signal-to-noise ratio (SNR) and two time increase in the imaging depth (5 cm). Another method of silver coating leads to a 5 dB improvement in the SNR of the modified seeds. An alternative approach in using dyed ethanol solution as a contrast enhancing agent by filling the spaces between two seeds is also reported. The result showed improvement comparable to the black paint method. Another goal is to propose a novel method of tissue typing in PA imaging. A temperature change in tissue can lead to changes of several tissue parameters which can be used for tissue typing. One of the parameters is the speed of sound in tissue, which increases in water-based non-fatty tissue and decreases in fatty tissue as temperature is raised. We show that on average, 6.9±1.5 %/min increase and 4.2±1.5 %/min decrease in PA intensity are observed in porcine liver and bovine fat samples respectively through one minute of laser heating. These results demonstrate that by analyzing the PA intensity change of the illuminated sample, one can extract characteristic information that can lead to tissue type differentiation.
Applied Science, Faculty of
Electrical and Computer Engineering, Department of
Graduate
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Holm, Åsa. "Mathematical Optimization of HDR Brachytherapy." Doctoral thesis, Linköpings universitet, Optimeringslära, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-99795.

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One out of eight deaths throughout the world is due to cancer. Developing new treatments and improving existing treatments is hence of major importance. In this thesis we have studied how mathematical optimization can be used to improve an existing treatment method: high-dose-rate (HDR) brachytherapy. HDR brachytherapy is a radiation modality used to treat tumours of for example the cervix, prostate, breasts, and skin. In HDR brachytherapy catheters are implanted into or close to the tumour volume. A radioactive source is moved through the catheters, and by adjusting where the catheters are placed, called catheter positioning, and how the source is moved through the catheters, called the dwelling time pattern, the dose distribution can be controlled. By constructing an individualized catheter positioning and dwelling time pattern, called dose plan, based on each patient's anatomy, it is possible to improve the treatment result. Mathematical optimization has during the last decade been used to aid in creating individualized dose plans. The dominating optimization model for this purpose is a linear penalty model. This model only considers the dwelling time pattern within already implanted catheters, and minimizes a weighted deviation from dose intervals prescribed by a physician. In this thesis we show that the distribution of the basic variables in the linear penalty model implies that only dwelling time patterns that have certain characteristics can be optimal. These characteristics cause troublesome inhomogeneities in the plans, and although various measures for mitigating these are already available, it is of fundamental interest to understand their cause. We have also shown that the relationship between the objective function of the linear penalty model and the measures commonly used for evaluating the quality of the dose distribution is weak. This implies that even if the model is solved to optimality there is no guarantee that the generated plan is optimal with respect to clinically relevant objectives, or even near-optimal. We have therefore constructed a new model for optimizing the dwelling time pattern. This model approximates the quality measures by the concept conditional value-at-risk, and we show that the relationship between our new model and the quality measures is strong. Furthermore, the new model generates dwelling time patterns that yield high-quality dose distributions. Combining optimization of the dwelling time pattern with optimization of the catheter positioning yields a problem for which it is rarely possible to find a proven optimal solution within a reasonable time frame. We have therefore developed a variable neighbourhood search heuristic that outperforms a state-of-the-art optimization software (CPLEX). We have also developed a tailored branch-and-bound algorithm that is better at improving the dual bound than a general branch-and-bound algorithm. This is a step towards the development of a method that can find proven optimal solutions to the combined problem within a reasonable time frame.
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Nouranian, Saman. "Information fusion for prostate brachytherapy planning." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/58305.

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Low-dose-rate prostate brachytherapy is a minimally invasive treatment approach for localized prostate cancer. It takes place in one session by permanent implantation of several small radio-active seeds inside and adjacent to the prostate. The current procedure at the majority of institutions requires planning of seed locations prior to implantation from transrectal ultrasound (TRUS) images acquired weeks in advance. The planning is based on a set of contours representing the clinical target volume (CTV). Seeds are manually placed with respect to a planning target volume (PTV), which is an anisotropic dilation of the CTV, followed by dosimetry analysis. The main objective of the plan is to meet clinical guidelines in terms of recommended dosimetry by covering the entire PTV with the placement of seeds. The current planning process is manual, hence highly subjective, and can potentially contribute to the rate and type of treatment related morbidity. The goal of this thesis is to reduce subjectivity in prostate brachytherapy planning. To this end, we developed and evaluated several frameworks to automate various components of the current prostate brachytherapy planning process. This involved development of techniques with which target volume labels can be automatically delineated from TRUS images. A seed arrangement planning approach was developed by distributing seeds with respect to priors and optimizing the arrangement according to the clinical guidelines. The design of the proposed frameworks involved the introduction and assessment of data fusion techniques that aim to extract joint information in retrospective clinical plans, containing the TRUS volume, the CTV, the PTV and the seed arrangement. We evaluated the proposed techniques using data obtained in a cohort of 590 brachytherapy treatment cases from the Vancouver Cancer Centre, and compare the automation results with the clinical gold-standards and previously delivered plans. Our results demonstrate that data fusion techniques have the potential to enable automatic planning of prostate brachytherapy.
Applied Science, Faculty of
Electrical and Computer Engineering, Department of
Graduate
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Kolkman-Deurloo, Inger Karine Kirsten. "Intraoperative HDR brachytherapy: present and future." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2007. http://hdl.handle.net/1765/8621.

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Liu, Derek Man Chun. "Chracterization of novel electronic brachytherapy system." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18737.

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The Axxent device developed by Xoft Inc. is a novel electronic brachytherapy system capable of generating x-rays up to 50 keV. The objective of this study is to characterize the x-ray beam and to model the x-ray tube using the Geant4 Monte Carlo code. Spectral measurements are done using an Amptek XR-100T CdTe spectrometer. Attenuation curves are measured using both a NE-2571 farmer chamber and a PTW-23342 parallel plate chamber. 2-D dose distributions are measured using EBT Gafchromic films. The Geant4 Monte Carlo code is bench-marked against BEAMnrc results. HVL values and effective energies are obtained from spectral measurements, attenuation curve measurements, and Geant4 simulations. The results mostly agree within one standard deviation. Measurements show that the HVL decreases with beam angle. However, this trend is not observed in Geant4 results. 2-D dose distributions are compared with Geant4 Monte Carlo results. The agreement is mostly within 10 %. However, there are significant differences aft of the source.
La sonde Axxent, conçu par Xoft inc., est un nouveau système de curiethérapie électronique qui peut générer des rayons X avec une énergie maximum de 50 keV. L'objectif de cette étude est de décrire le spectre de rayons X émis et de créer un modèle du tube à rayons X en utilisant le code de Monte Carlo Geant4. Les mesures de spectres ont été réalisées à l'aide d'un spectromètre CdTe XR-100T de marque Amptek. Les courbes d'atténuation ont été mesurées à l'aide de deux chambres d'ionisation: une chambre NE-2571 de type Farmer et une chambre PTW-23342 de type chambre plate. Des films Garchromiques EBT ont été utilisés pour la mesure de distributions de dose en 2 dimensions autour de la source. Les résultats obtenus avec le code Geant4 one été comparés avec les résultats générés grâce à un code de Monte Carlo différent: BEAMnrc. Les épaisseurs de demi-atténuation et les énergies effectives on été également déduites des mesures spectrales, des courbes d'atténuation et des simulations de Geant4. Les résultats s'accordent avec une différence de moins d'un écart-type dans la plupart des cas. Les mesures indiquent que les épaisseurs de demi-atténuation diminuent avec l'angle du rayon choisi pour la mesure. Par contre, cette tendance n'est pas observée dans les simulations Monte Carlo avec Geant4. La comparaison entre les mesures et les calculs de Geant4 des distributions de dose en deux dimensions montre un accord généralement meilleur que 10 %. Néanmoins, il y a des différences importantes en arriére de la source.
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Corsten, Maria J. (Maria Joanne) Carleton University Dissertation Physics. "Ionization chamber response for brachytherapy sources." Ottawa, 1995.

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Sehgal, Varun. "Improved dosimetry techniques for intravascular brachytherapy." [Gainesville, Fla.] : University of Florida, 2001. http://etd.fcla.edu/etd/uf/2001/anp1584/Diss.pdf.

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Thesis (Ph. D.)--University of Florida, 2001.
Title from first page of PDF file. Document formatted into pages; contains xiii, 140 p.; also contains graphics. Vita. Includes bibliographical references (p. 132-139).
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Books on the topic "Brachytherapy"

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Devlin, Phillip M., Robert A. Cormack, Caroline L. Holloway, and Alexandra J. Stewart, eds. Brachytherapy. New York, NY: Springer Publishing Company, 2015. http://dx.doi.org/10.1891/9781617052613.

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Yoshioka, Yasuo, Jun Itami, Masahiko Oguchi, and Takashi Nakano, eds. Brachytherapy. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-0490-3.

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Montemaggi, Paolo, Mark Trombetta, and Luther W. Brady, eds. Brachytherapy. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3.

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Ron, Waksman, ed. Vascular brachytherapy. 2nd ed. Armonk, NY: Futura Pub. Co., 1999.

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R, Waksman, ed. Vascular brachytherapy. Veenendaal: Nucletron B.V., 1996.

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Joint American Association of Physicists in Medicine/American Brachytherapy Society Summer School. Brachytherapy physics. 2nd ed. Madison, WI: Meds Pub., 2006.

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Minnesota. Health Technology Advisory Committee., ed. Intracoronary brachytherapy. [St. Paul, Minn.]: Health Technology Advisory Committee, 2001.

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1920-, Pierquin Bernard, Wilson J. F, and Chassagne D, eds. Modern brachytherapy. New York: Distributed by Year Book Medical Publishers, 1987.

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Bruce, Thomadsen, Rivard Mark J, Butler Wayne M, and American Association of Physicists in Medicine., eds. Brachytherapy physics. 2nd ed. Madison, WI: Published for American Association of Physicists in Medicine by Medical Physics Pub., 2005.

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Lemoigne, Yves, and Alessandra Caner, eds. Radiotherapy and Brachytherapy. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-3097-9.

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Book chapters on the topic "Brachytherapy"

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Yaeger, Theodore E., Luther W. Brady, Mark Trombetta, and Paolo Montemaggi. "Introduction." In Brachytherapy, 1–4. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_1.

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Pignol, Jean-Philippe, and Juanita Crook. "Breast Brachytherapy: Permanent Breast Seed Implants – How and Why?" In Brachytherapy, 185–96. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_10.

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Trombetta, Mark, Thomas B. Julian, and Jean-Michel Hannoun-Levi. "Breast Brachytherapy: Brachytherapy in the Management of Ipsilateral Breast Tumor Recurrence." In Brachytherapy, 197–212. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_11.

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Renz, Paul, Matthew Van Deusen, Rodney J. Landreneau, and Athanasios Colonias. "Thoracic Brachytherapy." In Brachytherapy, 213–38. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_12.

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Tselis, Nikolaos, Konrad Mohnike, and Jens Ricke. "Image-Guided High-Dose Rate Brachytherapy in the Treatment of Liver Cancer." In Brachytherapy, 239–52. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_13.

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Vargo, John A., Akila N. Viswanathan, Beth A. Erickson, and Sushil Beriwal. "Gynecologic Brachytherapy: Endometrial Cancer." In Brachytherapy, 253–68. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_14.

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Vargo, John A., Akila N. Viswanathan, Beth A. Erickson, and Sushil Beriwal. "Gynecologic Brachytherapy: Cervical Cancer." In Brachytherapy, 269–78. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_15.

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Vargo, John A., Akila N. Viswanathan, Beth A. Erickson, and Sushil Beriwal. "Gynecologic Brachytherapy: Vaginal Cancer." In Brachytherapy, 279–85. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_16.

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Guerrieri, Patrizia, and Bryan C. Coopey. "Gynecologic Brachytherapy: Image Guidance in Gynecologic Brachytherapy." In Brachytherapy, 287–97. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_17.

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Lim, Pei Shuen, and Peter Hoskin. "Prostate: Low Dose Rate Brachytherapy." In Brachytherapy, 299–317. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26791-3_18.

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Conference papers on the topic "Brachytherapy"

1

Persons, Timothy M., Richard L. Webber, Paul F. Hemler, Wolfram Bettermann, and J. Daniel Bourland. "Brachytherapy volume visualization." In Medical Imaging 2000, edited by Seong K. Mun. SPIE, 2000. http://dx.doi.org/10.1117/12.383064.

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Zequn, Li, Li Changle, Zhang Xuehe, Liu Gangfeng, and Zhao Jie. "The Robot System for Brachytherapy." In 2019 IEEE/ASME International Conference on Advanced Intelligent Mechatronics (AIM). IEEE, 2019. http://dx.doi.org/10.1109/aim.2019.8868377.

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DeWerd, Larry A., Stephen D. Davis, Anatoly Rosenfeld, Tomas Kron, Francesco d’Errico, and Marko Moscovitch. "Dosimetric Characteristics for Brachytherapy Sources." In CONCEPTS AND TRENDS IN MEDICAL RADIATION DOSIMETRY: Proceedings of SSD Summer School. AIP, 2011. http://dx.doi.org/10.1063/1.3576168.

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Alexander Arcos Rosero, Wilmmer, Angélica Bueno Barbezan, Carlos Alberto Zeituni, and Maria Elisa Chuery Martins Rostelato. "Gold radioactive nanoparticles for brachytherapy." In RAD Conference. RAD Centre, 2023. http://dx.doi.org/10.21175/rad.abstr.book.2023.42.3.

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Pisla, Doina, Dragos Cocorean, Calin Vaida, Bogdan Gherman, Adrian Pisla, and Nicolae Plitea. "Application Oriented Design and Simulation of an Innovative Parallel Robot for Brachytherapy." In ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/detc2014-35047.

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The paper presents the design and simulation of a new 5-DOF parallel robot named PARA-BRACHYROB used for brachytherapy. Brachytherapy (BT) is an advanced cancer treatment technique, where radioactive seeds are delivered directly in the tumor without damaging the proximal healthy tissues. Due to the tremendous therapeutic potential of brachytherapy, many researches are encouraged to provide solutions for enhanced placement of BT devices inside the patient body, thus further developing brachytherapy robotic systems. Therefore the paper presents an innovative CT-Scan compatible robotic device for this application. The PARA-BRACHYROB system consists of a parallel robot with five degrees of freedom (DOF) for needle positioning and orientation up to the insertion point in the patient body and a 1-DOF mechanism for the needle insertion. The kinematic models of PARA-BRACHYROB are presented and validated through a multi-body simulation including a short description of the numerical and simulation results for the developed model.
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Rabiei, Mahsa, and Bardia Konh. "A Portable Robot to Perform Prostate Brachytherapy with Active Needle Steering and Robot-Assisted Ultrasound Tracking." In 2022 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/dmd2022-1014.

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Abstract Brachytherapy is an internal radiation therapy method for prostate cancer that involves placement of radioactive seeds close to the cancerous cells. Robotic needle insertion systems have been proposed in the past to help physicians to improve outcomes of brachytherapy. This work presents design and development of a portable robotic brachytherapy system to operate a tendon-driven active needle based on physician’s input. The system enables manual positioning of the needle to choose appropriate puncture positions as well as robotic manipulation mechanisms for needle insertion and bending. The system also allows for automatic movement of an ultrasound probe to visualize the needle tip in a needle insertion task in real time.
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Podder, Tarun K., Ivan Buzurovic, and Yan Yu. "Multichannel Robot for Image-Guided Brachytherapy." In 2010 IEEE International Conference on BioInformatics and BioEngineering. IEEE, 2010. http://dx.doi.org/10.1109/bibe.2010.41.

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Tianhao Zhang and R. Patel. "Optimization-based dosimetry planning for brachytherapy." In 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2011. http://dx.doi.org/10.1109/iembs.2011.6091347.

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Martı́nez-Dávalos, A. "Monte Carlo dosimetry in HDR brachytherapy." In The fourth mexican symposium on medical physics. AIP, 2000. http://dx.doi.org/10.1063/1.1328950.

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Kuo, Nathanael, Junghoon Lee, Clare Tempany, Matthias Stuber, and Jerry Prince. "MRI-based prostate brachytherapy seed localization." In 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro. IEEE, 2010. http://dx.doi.org/10.1109/isbi.2010.5490259.

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Reports on the topic "Brachytherapy"

1

Prasher, Sparsh, and Frank Chinegwundoh. Brachytherapy for prostate cancer. BJUI Knowledge, May 2020. http://dx.doi.org/10.18591/bjuik.0186.

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Nath, Ravinder, Lowell Anderson, Douglas Jones, Clifton Ling, Robert Loevinger, Jeffrey Williamson, and William Hanson. Specification of Brachytherapy Source Strength. AAPM, 1987. http://dx.doi.org/10.37206/20.

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Davda, Reena, and Amani Chowdhury. HDR brachytherapy for prostate cancer. BJUI Knowledge, May 2021. http://dx.doi.org/10.18591/bjuik.0686.

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Jain, Ameet. Intra-Operative Dosimetry in Prostate Brachytherapy. Fort Belvoir, VA: Defense Technical Information Center, April 2008. http://dx.doi.org/10.21236/ada484779.

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Jain, Ameet. Intra-Operative Dosimetry in Prostate Brachytherapy. Fort Belvoir, VA: Defense Technical Information Center, November 2006. http://dx.doi.org/10.21236/ada463119.

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Jain, Ameet. Intra-Operative Dosimetry in Prostate Brachytherapy. Fort Belvoir, VA: Defense Technical Information Center, November 2007. http://dx.doi.org/10.21236/ada482977.

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Rohatgi, Upendra, and Michael Furey. Miniature Neutron Generator for Brachytherapy Tumor Treatment. Office of Scientific and Technical Information (OSTI), March 2011. http://dx.doi.org/10.2172/1079919.

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Seltzer, Stephen M. Monte Carlo modeling for intravascular brachytherapy sources. Gaithersburg, MD: National Institute of Standards and Technology, 2002. http://dx.doi.org/10.6028/nist.ir.6871.

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Weaver, James T., Thomas P. Loftus, and Robert Loevinger. Calibration of gamma-ray-emitting brachytherapy sources. Gaithersburg, MD: National Bureau of Standards, 1988. http://dx.doi.org/10.6028/nbs.sp.250-19.

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Choi, C. K. Monte Carol-Based Dosimetry of Beta-Emitters for Intravascular Brachytherapy. Office of Scientific and Technical Information (OSTI), June 2002. http://dx.doi.org/10.2172/798524.

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