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Dissertations / Theses on the topic 'Brachytherypy'

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Published: 4 June 2025
Last updated: 1 August 2025

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1

Wirth, Manfred P., and Oliver W. Hakenberg. "Brachytherapy for Prostate Cancer." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-133901.

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2

Melhus, Christopher S. (Christopher Scott) 1974. "Advanced brachytherapy dosimetric considerations." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43808.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2008.<br>Includes bibliographical references (p. 131-139).<br>The practice of brachytherapy and brachytherapy dosimetry was investigated with emphasis on evaluations of dose distributions and shielding considerations for both photon- and neutron-emitting radionuclides. Monte Carlo simulation methods were employed to calculate dose distributions for virtual and commercial brachytherapy sources. Radionuclides studied were 103Pd, 1251, 131Cs, 137Cs, 169b, 192Ir, and 252Cf. 252Cf sources also emit neutrons from spontaneous fi
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3

Wirth, Manfred P., and Oliver W. Hakenberg. "Brachytherapy for Prostate Cancer." Karger, 1999. https://tud.qucosa.de/id/qucosa%3A27547.

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4

Pan, Leo Lijia. "Photoacoustic imaging for prostate brachytherapy." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/48478.

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Photoacoustic (PA) imaging is an emerging imaging modality that relies on the PA effect. The PA effect is caused by exposing an optically absorbing sample to near-infrared light which causes the sample to experience a temporary temperature increase through optical absorption. The heated region undergoes thermoelastic expansion and produces an abrupt and localized pressure change. This change results in a transient PA wave that propagates out toward the sample surface for collection by an ultrasound (US) transducer. Through image reconstruction, the optical property of the sample can be obtaine
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5

Holm, Åsa. "Mathematical Optimization of HDR Brachytherapy." Doctoral thesis, Linköpings universitet, Optimeringslära, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-99795.

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One out of eight deaths throughout the world is due to cancer. Developing new treatments and improving existing treatments is hence of major importance. In this thesis we have studied how mathematical optimization can be used to improve an existing treatment method: high-dose-rate (HDR) brachytherapy. HDR brachytherapy is a radiation modality used to treat tumours of for example the cervix, prostate, breasts, and skin. In HDR brachytherapy catheters are implanted into or close to the tumour volume. A radioactive source is moved through the catheters, and by adjusting where the catheters are pl
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6

Nouranian, Saman. "Information fusion for prostate brachytherapy planning." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/58305.

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Low-dose-rate prostate brachytherapy is a minimally invasive treatment approach for localized prostate cancer. It takes place in one session by permanent implantation of several small radio-active seeds inside and adjacent to the prostate. The current procedure at the majority of institutions requires planning of seed locations prior to implantation from transrectal ultrasound (TRUS) images acquired weeks in advance. The planning is based on a set of contours representing the clinical target volume (CTV). Seeds are manually placed with respect to a planning target volume (PTV), which is an ani
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7

Kolkman-Deurloo, Inger Karine Kirsten. "Intraoperative HDR brachytherapy: present and future." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2007. http://hdl.handle.net/1765/8621.

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8

Liu, Derek Man Chun. "Chracterization of novel electronic brachytherapy system." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18737.

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The Axxent device developed by Xoft Inc. is a novel electronic brachytherapy system capable of generating x-rays up to 50 keV. The objective of this study is to characterize the x-ray beam and to model the x-ray tube using the Geant4 Monte Carlo code. Spectral measurements are done using an Amptek XR-100T CdTe spectrometer. Attenuation curves are measured using both a NE-2571 farmer chamber and a PTW-23342 parallel plate chamber. 2-D dose distributions are measured using EBT Gafchromic films. The Geant4 Monte Carlo code is bench-marked against BEAMnrc results. HVL values and effective energies
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9

Corsten, Maria J. (Maria Joanne) Carleton University Dissertation Physics. "Ionization chamber response for brachytherapy sources." Ottawa, 1995.

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10

Sehgal, Varun. "Improved dosimetry techniques for intravascular brachytherapy." [Gainesville, Fla.] : University of Florida, 2001. http://etd.fcla.edu/etd/uf/2001/anp1584/Diss.pdf.

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Thesis (Ph. D.)--University of Florida, 2001.<br>Title from first page of PDF file. Document formatted into pages; contains xiii, 140 p.; also contains graphics. Vita. Includes bibliographical references (p. 132-139).
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11

Pritz, Jakub. "Biological Effective Dose (BED) Distribution Matching for Obtaining Brachytherapy Prescription Doses & Dosimetric Optimization for Hybrid Seed Brachytherapy." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3298.

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Radioactive seed implant brachytherapy is a common radiotherapy treatment method for prostate cancer. In current clinical practice, a seed consists of a single isotope, such as 125I or 103Pd. A seed containing a mixture of two isotopes has been proposed for prostate cancer treatment. This study investigates a method for defining a prescription dose for new seed compositions based on matching the biological equivalent dose (BED) of a reference plan. Ten prostate cancer cases previously treated using single isotope seeds (5 using 125I seeds and 5 using 103Pd seeds) were selected for this study
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12

Sampath, Varsha. "Transrectal ultrasound image processing for brachytherapy applications /." Online version of thesis, 2006. https://ritdml.rit.edu/dspace/handle/1850/2618.

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13

Mazzella, Ann Marie. "The quality of life after pulmonary brachytherapy /." Staten Island, N.Y. : [s.n.], 1993. http://library.wagner.edu/theses/nursing/1993/thesis_nur_1993_mazze_quali.pdf.

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14

Sims, Elliot Craig. "Optimizing coronary artery brachytherapy using targeted radioimmunotherapy." Thesis, Queen Mary, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412000.

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15

Stewart, Alexander J. "Computed Tomography Based Dosimetric Evaluation of Brachytherapy." Thesis, Southampton Solent University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.515849.

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16

Haworth, Annette. "Post implant dosimetric analysis for prostate brachytherapy." University of Western Australia. School of Surgery and Pathology, 2005. http://theses.library.uwa.edu.au/adt-WU2005.0107.

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17

Parker, William 1969. "Brachytherapy dosimetry with fricke-gelatin and MRI." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=22786.

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Magnetic Resonance Imaging (MRI) and Fricke-gelatin dosimetry are used to measure absorbed dose distributions from high dose rate (HDR) brachytherapy treatments. The high activity of the HDR brachytherapy source is suitable for the prompt delivery of the high doses required to give changes in the Fricke-gelatin Nuclear Magnetic Resonance (NMR) characteristics which are readily detected by MRI. The MR images can map 3D dose distributions deposited in the Fricke-gelatin matrix. Spin-lattice relaxation times (T1) and rates (R1) are computed from MR images of irradiated Fricke gelatin phantoms in
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18

Issa, Fatma Mabruk. "Doped optical fibres thermoluminescence dosimetry for brachytherapy." Thesis, University of Surrey, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580336.

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In the various brachytherapy techniques the intent is to deliver as high a tumour dose as possible, limited only by surrounding normal tissue tolerance. The main feature of the techniques is very steep dose gradients, representing a potential limiting factor in accurate dose distribution measurements around sources. Dose distributions at distances less than 1 cm are therefore normally generated using either validated Monte Carlo (MC) simulations or standard dose calculation formalisms, for example that of AAPM TG 43, while dose measurements can only be performed at larger distances, normally g
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19

Yang, Wenjun. "Rotating-shield brachytherapy (RSBT) for cervical cancer." Thesis, University of Iowa, 2012. https://ir.uiowa.edu/etd/3410.

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Purpose: To assess rotating shield brachytherapy (RSBT) delivered with the electronic brachytherapy (eBT) source comparing to intracavitary (IC) and intracavitary plus supplemental interstitial brachytherapy (IC+IS BT) delivered with a conventional 192Ir radioactive source. Method and Materials: IC, IC+IS and RSBT treamtent plan were simulated for 5 patients with bulky (>40 cc) cervical cancer. One BT plan for each patient (fraction 1) guided by magnetic resonance imaging (MRI) was used in our treatment planning system (TPS). A bio- and MRI-compatible polycarbonate (Makrolon Rx3158) intrauteri
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20

Liu, Yunlong. "Treatment plan optimization for rotating-shield brachytherapy." Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/1680.

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In this thesis, we aim to develop fundamentally new techniques and algorithms for efficiently computing rotating-shield brachytherapy (RSBT) treatment plans. We propose that these algorithms will pave the way for making RSBT available in clinical practices. RSBT is an intensity modulated high-dose-rate brachytherapy (HDR-BT) technique. Theoretically, RSBT offers advantages over the conventional HDR-BT. Although this technique is promising in theory, its application in practice is still at an early stage. The RSBT technique entails rotating a radiation-attenuating shield about a brachytherapy s
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21

Dadkhah, Hossein. "Developing novel techniques for next generation rotating shield brachytherapy." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/6931.

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Multi-helix rotating shield brachytherapy (RSBT) applicator and multi-source RSBT apparatus are two novel intensity-modulated brachytherapy techniques for the treatment of cervical and prostate cancer, respectively. The use of imaging techniques such as magnetic resonance imaging guided brachytherapy has enabled the precise identification and contouring of tumor volumes for treatment planning, as well as demonstrated the challenges associated with using conventional high dose rate brachytherapy (HDR-BT) approaches to conform the radiation dose to the target and avoid surrounding sensitive heal
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22

Bannon, Elizabeth. "Dosimetric characterization of elongated brachytherapy sources using Monte Carlo methods." Thesis, Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/33923.

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Current brachytherapy treatment planning systems are unable to accurately calculate dose distributions in the vicinity of brachytherapy sources having active lengths much greater than 5 mm. While low dose-rate ¹³⁷Cs sources are dosimetrically characterized using antiquated along-away tables with simple linear-linear interpolation errors in dose calculation exceeding 30% occur due to algorithm inadequacy. The method presented in this thesis permits dosimetric characterization of elongated brachytherapy sources with active lengths 0 < L < 10 cm for implementation on an FDA-approved clinical TPS.
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23

Usgaonker, Susrut Rajanikant. "MCNP modeling of prostate brachytherapy and organ dosimetry." Thesis, Texas A&M University, 2004. http://hdl.handle.net/1969.1/305.

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Using the computer code Monte Carlo N-Particle (MCNP), doses were calculated for organs of interest such as the large intestine, urinary bladder, testes, and kidneys while patients were undergoing prostate brachytherapy. This research is important because the doses delivered to the prostate are extremely high and the organs near the prostate are potentially at risk for receiving high doses of radiation, leading to increased probabilities of adverse health effects such as cancer. In this research, two MCNP version 4C codes were used to calculate the imparted energies to the organs of interest
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24

Wen, Xu. "Towards ultrasound-based intraoperative dosimetry for prostate brachytherapy." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/26640.

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Prostate brachytherapy is a widely used treatment of localized prostate cancer. Intra-operative dose feedback would bring many benefits to patients and healthcare practitioners. Detection of brachytherapy seeds and segmentation of prostate boundaries play key roles in dosimetry for prostate brachytherapy. However, seed detection and prostate segmentation using conventional B-mode transrectal ultrasound still remains a challenge for prostate brachytherapy, mainly due to the small size of brachytherapy seeds in the relatively low-quality B-mode ultrasound images and due to the poor contrast betw
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Tozer-Loft, Stephen M. "Dose volume analysis in brachytherapy and stereotactic radiosurgery." Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366100.

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26

Hamdan, Iyas. "Multimodal Image Registration in Image-Guided Prostate Brachytherapy." Thesis, Ecole nationale supérieure Mines-Télécom Atlantique Bretagne Pays de la Loire, 2017. http://www.theses.fr/2017IMTA0002/document.

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Le cancer de la prostate est le cancer le plus fréquent chez l'homme en France et aux pays occidentaux. Il est la troisième cause de décès liés au cancer, étant responsable d'environ 10% des morts. La curiethérapie, une technique de radiothérapie, est liée à une meilleure qualité de vie après le traitement, par rapport aux autres méthodes de traitement. La curiethérapie de la prostate consiste à insérer des sources radioactives dans la prostate afin de délivrer une dose d'irradiation localisée à la tumeur tout en protégeant les tissus sains environnants. L'imagerie multimodale est utilisée afi
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27

Girum, Kibrom Berihu. "Artificial intelligence for image-guided prostate brachytherapy procedures." Thesis, Bourgogne Franche-Comté, 2020. http://www.theses.fr/2020UBFCI012.

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Les procédures de radiothérapie visent à exposer les cellules cancéreuses aux rayonnements ionisants. L'implantation permanente de sources radioactives à proximité des cellules cancéreuses est une technique classique pour guérir le cancer de la prostate à un stade précoce. Le processus implique l'acquisition d'images du patient, la délimitation des volumes cibles et des organes à risque à l'aide de l'imagerie, la planification du traitement, l’implantation de grains radioactifs guidées par l'image et l'évaluation post-implantatoire. L'analyse d'images médicales basée sur l'intelligence artific
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28

Nalcacioglu, Ismail Ahmet. "An automated software system for brachytherapy source location." [Florida] : State University System of Florida, 2000. http://etd.fcla.edu/etd/uf/2000/amt2437/nalcacioglu.pdf.

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Thesis (M.S.)--University of Florida, 2000.<br>Title from first page of PDF file. Document formatted into pages; contains ix, 38 p.; also contains graphics. Vita. Includes bibliographical references (p. 37).
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Lam, Steve Troluong. "Analysis tools for brachytheraphy seed reconstruction /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/6027.

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30

Rodgers, Joseph J. "Radiochromic film dosimetry system for endovascular brachytherapy source calibration : a method and its uncertainties." Thesis, Georgia Institute of Technology, 1996. http://hdl.handle.net/1853/16468.

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31

Shum, Tsz-hang, and 岑梓恆. "A high spatial and temporal resolutions quality assurance tool for checking the accuracy of HDR source dwell positions and times." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193526.

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In High Dose Rate (HDR) brachytherapy, treatment dose to patients is highly dependent on the accuracy of positioning and duration of the source. Source misplacement or wrong duration of treatment could potentially result in adverse clinical side effects to patients. In order to maintain successful treatment for patients, an independent Quality Assurance (QA) verification is crucial to measure the High Dose Rate (HDR) source positioning and dwell time periodically to ensure the prescribed dose is correct and safe for brachytherapy treatment. The current QA practice used to validate the accur
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32

Jung, Jae Won. "142pr glass seeds for the brachytherapy of prostate cancer." Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/5738.

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A beta-emitting glass seed was proposed for the brachytherapy treatment of prostate cancer. Criteria for seed design were derived and several beta-emitting nuclides were examined for suitability. 142Pr was selected as the isotope of choice. Seeds 0.08 cm in diameter and 0.9 cm long were manufactured for testing. The seeds were activated in the Texas A&M University research reactor. The activity produced was as expected when considering the meta-stable state and epi-thermal neutron flux. The MCNP5 Monte Carlo code was used to calculate the quantitative dosimetric parameters suggested in the Ame
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33

Toye, Warren, and michelletoye@optusnet com au. "HDR Brachytherapy: Improved Methods of Implementation and Quality Assurance." RMIT University. Applied Sciences, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080528.091630.

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This thesis describes experimental work performed (1998-2001) during the author's involvement with the Brachytherapy group at the Peter MacCallum Cancer Centre (PMCC), where he was employed by its Department of Physical Sciences and subsequent modeling and analytical studies. When PMCC added HDR brachytherapy to its radiation therapy practice, an existing operating suite was considered the ideal location for such procedures to be carried out. The integration of brachytherapy into the theatre environment was considered logical due to the relatively invasive nature of brachytherapy techniques an
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34

Yao, Zhen. "Design and Synthesis of Porphyrins for Targeted Molecular Brachytherapy." NCSU, 2006. http://www.lib.ncsu.edu/theses/available/etd-12082006-143415/.

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New approaches are urgently needed for treatment of cancer. The inherent heterogeneity of cells in solid tumors has thwarted most approaches developed to date. A fundamentally new approach, targeted molecular brachytherapy, also known as selective targeted amplified radiotherapy (S.T.A.R.), is attractive conceptually but has not yet been implemented. This new method selectively accumulates radioactive precipitates in tumor sites by systemic treatment of distinct agents in a sequential manner. One of the key agents for such a therapy is a soluble, precipitable reagent (SPR). The essence of this
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35

Dehghan, Marvast Ehsan. "Needle insertion simulation and path planning for prostate brachytherapy." Thesis, University of British Columbia, 2009. http://hdl.handle.net/2429/7788.

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Low dose rate prostate brachytherapy has emerged as a treatment option for localized prostate cancer. During prostate brachytherapy, tiny radioactive capsules - seeds - are implanted inside the tissue using long needles. The quality of the treatment depends on the accuracy of seed delivery to their desired positions. Prostate deformation and displacement during insertion and lack of sufficient visual feedback complicate accurate targeting and necessitates extensive training on the part of the physician. Needle insertion simulators can be useful for physician training. In addition, insertion of
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36

Wai, Philip. "The application of 3-d dosimetry in brachytherapy treatment." Thesis, University of Surrey, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.504948.

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In the UK, prostate cancer is the second most commonly occurring cancer in men.. The number of prostate cancer incidents is expected to increase due to improved screening and diagnostic techniques, whilst the mortality rate continues to fall as the variety ofavailable treatments increases. This research focuses on the commonly used brachytherapy seed OncoSeed™ Model 6711 manufactured by GE Healthcare. lodine-125 seeds are surgically implanted and left inside the prostate permanently to obtain local control of the malignant prostate cancer. Prior to the surgical procedure, a treatment plan is c
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Al-Qaisieh, Bashar. "Dose analysis of iodine-125 seeds for prostate brachytherapy." Thesis, University of Leeds, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413209.

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38

Mucheusi, Longino Kabakiza. "Brachytherapy in cancer of the cervix : an African perspective." Thesis, Cape Peninsula University of Technology, 2012. http://hdl.handle.net/20.500.11838/1548.

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Thesis (MTech (Radiography))--Cape Peninsula University of Technology, 2012<br>Introduction: Brachytherapy plays an essential role in the management of patients with cervical cancer. The high cervical cancer burden in Africa presents challenges with regard to provision and sustainability of these services. This study analysed treatment outcomes of two brachytherapy modalities, high dose rate (HDR) and low dose rate (LDR) intracavitary treatment for patients with cervical cancer, and evaluated the problems and challenges of the provision of these services within the African context. Methodol
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Cui, Songye, and Songye Cui. "Multi-criteria optimization algorithms for high dose rate brachytherapy." Doctoral thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/37180.

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L’objectif général de cette thèse est d’utiliser les connaissances en physique de la radiation, en programmation informatique et en équipement informatique à la haute pointe de la technologie pour améliorer les traitements du cancer. En particulier, l’élaboration d’un plan de traitement en radiothérapie peut être complexe et dépendant de l’utilisateur. Cette thèse a pour objectif de simplifier la planification de traitement actuelle en curiethérapie de la prostate à haut débit de dose (HDR). Ce projet a débuté à partir d’un algorithme de planification inverse largement utilisé, la planificatio
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Amoush, Ahmad A. "Error Analysis of non-TLD HDR Brachytherapy Dosimetric Techniques." University of Cincinnati / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307105202.

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Mach, Lisa. "Deformable registration when combining brachytherapy and external beam radiotherapy." Thesis, KTH, Medicinsk avbildning, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-300045.

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Patients with cervical cancer are treated both with external beam radiotherapy(EBRT) and brachytherapy (BT) which involves an applicator. During the treatments, CT-images are taken and to perform dose calculations, deformable image registration (DIR) is performed. The image registration involves many challenges, for example, the organs may have different shapes and volumes in the images and the images have different intensities due to the applicator. Many DIR-methods are available but they fail in aligning the multiple organs correctly and simultaneously. This project aimed for developing a me
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Kaisaier, Abudukadier. "Deleterious effect of brachytherapy on vasomotor response to exercise." [S.l.] : [s.n.], 2003. http://www.zb.unibe.ch/download/eldiss/03kaisaier_a.pdf.

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43

Mehrtash, Alireza. "Needle Navigation for Image Guided Brachytherapy of Gynecologic Cancer." Thesis, KTH, Skolan för kemi, bioteknologi och hälsa (CBH), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-248042.

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In the past twenty years, the combination of the advances in medical imaging technologies and therapeutic methods had a great impact in developing minimally invasive interventional procedures. Although the use of medical imaging for the surgery and therapy guidance dates back to the early days of x-ray discovery, there is an increasing evidence in using the new imaging modalities such as computed tomography (CT), magnetic reso- nance imaging (MRI) and ultrasound in the operating rooms. The focus of this thesis is on developing image-guided interventional methods and techniques to support the r
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44

Li, Xing. "Novel brachytherapy techniques for cervical cancer and prostate cancer." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/1682.

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Intensity-modulated brachytherapy techniques, compensator-based intensity modulated brachytherapy (CBT) and interstitial rotating shield brachytherapy (I-RSBT), are two novel conceptual radiation therapies for treating cervical and prostate cancer, respectively. Compared to conventional brachytherapy techniques for treating cervical cancer, CBT can potentially improve the dose conformity to the high-risk clinical target volume (CTV) of the cervix in a less invasive approach. I-RSBT can reduce the dose delivered to the prostate organ at risks (OARs) with the same radiation dose delivered to the
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45

Wahlgren, Thomas. "High dose rate brachytherapy boost for localized prostate cancer : clinical and patient-reported outcomes/." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-931-9/.

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46

Gautam, Bhoj Raj. "Study of Dosimetric and Thermal Properties of a Newly Developed Thermo-brachytherapy Seed for Treatment of Solid Tumors." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1365181537.

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47

Leung, To-wai. "High-dose-rate intracavitary brachytherapy in the treatment of nasopharyngeal carcinoma." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B39557315.

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48

Langdal, Ingrid. "Dosimetry and evaluation of algorithm for inverseoptimized doseplanning for brachytherapy." Thesis, Norwegian University of Science and Technology, Department of Physics, 2009. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-6287.

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<p>Purpose</p><p>Individual optimized treatment planning is recommended when creating treatment plans for brachytherapy of cervical cancer. Manual alteration of the dose distribution is time consuming and the treatment plan may be dependent on the person creating it. Inverse planning simulated anneahng (IPSA) is an algorithm that can optimize the dose distribution considering dose to several delineated structures. This algorithm, currently available in the treatment planning system Masterplan, has been evaluated for brachytherapy of cervical cancer. The Masterplan system simulates a source typ
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49

Zakariaee, Kouchaksaraee Roja. "Localized bladder dose accumulation in multi-fraction cervical cancer brachytherapy." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/60173.

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Radiation therapy in the definitive treatment of locally advanced carcinoma of the cervix consists of external beam radiotherapy (EBRT) combined with image-guided high-dose-rate (IG HDR) intracavitary brachytherapy (ICBT). IG HDR-ICBT is a relatively new, advanced form of brachytherapy treatment planning and delivery that still relies largely on dose criteria based either on clinical experience using older techniques, or on limited data. Calculation of cumulative dose received over multiple treatment fractions currently utilizes dose-volume-histograms (DVH), which do not provide information ab
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Brunet-Benkhoucha, Malik. "Tomosynthesis-based intraoperative dosimetry for low dose rate prostate brachytherapy." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32401.

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Abstract:
The aim of this study is to develop an intraoperative dose assessment procedure that can be performed after an I-125 prostate seed implantation, while the patient is still under anaesthesia. To accomplish this, we reconstruct the 3D position of each seed and co-register it with the prostate contour acquired with a transrectal ultrasound (TRUS) probe. Our seed detection method involves a tomosynthesis-based filtered reconstruction of the volume of interest requiring 7 projections acquired over an angle of
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