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1

Smith-White, Margaret A. Medical Sciences Faculty of Medicine UNSW. "A functional study of neuropeptide Y mediated attenuation of vagal-evoked bradycardia." Awarded by:University of New South Wales. School of Medical Sciences, 2003. http://handle.unsw.edu.au/1959.4/19090.

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In the heart, neuropeptide Y (NPY) released during stimulation of the sympathetic nerve attenuates vagal-evoked bradycardia for a prolonged period. The inhibitory action of NPY is proposed as being Y2 receptor mediated. In rat and mouse, anaesthetised with sodium pentobarbitone, the selective Y2 receptor antagonist BIIE0246 reduced the inhibition of cardiac vagal activity evoked by a Y2 agonist, N-acetyl [Leu28, 31] NPY 24-36. BIIE0246 also reduced the inhibitory effect on vagal action evoked by stimulation of the sympathetic nerve. Deletion of the receptor in Y2 receptor-knockout mice ab
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2

Ruck, Sylvia A. "Induced Bradycardia Effects on Angiogenesis, Growth and Development in Early Development in Chicken Embryos, Gallus Domesticus." Thesis, University of North Texas, 2010. https://digital.library.unt.edu/ark:/67531/metadc33199/.

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Cardiac performance, angiogenesis and growth was investigated during early chicken development. Heart rate, and thus arterial pulse pressure and cardiac output, were altered with the bradycardic drug ZD7288. Heart rates at 72 h of development of control embryos and those dosed with chicken Ringer were not different at 171 bpm. Acute and chronic application of ZD7288 caused significant bradycardia. Chronic dosing of Ringer and ZD7288 changed neither eye diameter nor development rate. Chronic dosing of ZD7288 did not significantly alter CAM vessel density close to the embryo (2, 3 and 4 mm) but
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3

Manley, Elizabeth. "Apneic Bradycardia : terrestrial and aquatic responses in man under working conditions." Thesis, Rhodes University, 1989. http://hdl.handle.net/10962/d1001838.

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The focus of this research was the reappraisal in physiological and psychophysical terms of current equivocal theories regarding the onset, course and termination of apneic bradycardia. Sixteen healthy male subjects participated in four separate testing sessions . Maximal oxygen consumption (VO₂ max) was measured on land and underwater using an identical direct, continuous progressive cycle ergometer test. On each of two other occasions subjects exercised in either environment at 50, 70 and 90% of the appropriate VO₂ max, during which time heart rate was continuously recorded. An initial apnei
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4

Subramanian, Melanie. "Relative Bradycardia With Hypertension in Traumatic Brain Injury: A Marker for Mortality?" Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17295909.

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Traumatic brain injury (TBI) is a leading cause of death in patients under 45 years of age. Hypertension has been shown to be associated with increased mortality in patients with moderate to severe traumatic brain injury (TBI). Furthermore, it is known that relative bradycardia is associated with increased mortality in hypotensive patients. We conducted a study to evaluate the relationship of initial heart rate (HR) with outcome in hypertensive TBI patients. This was a retrospective study of adult patients with moderate to severe blunt TBI (GCS <13) that presented to a Level I trauma center (2
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5

St-Hilaire, Marie. "Chémoréflexes laryngés induits par l'acide, l'eau vs le salin chez les agneaux nouveau-nés durant le sommeil calme." Mémoire, Université de Sherbrooke, 2004. http://savoirs.usherbrooke.ca/handle/11143/3789.

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Mise en contexte : Les chémoréflexes laryngés (CRI) sont déclenchés suite au contact entre un liquide et la muqueuse laryngée. Chez un organisme mature, ces CRL sont responsables de mécanismes de protection des voies aériennes inférieures (VAI) tels que déglutitions, toux et réaction d'éveil afin d'éviter l'aspiration. Par contre, chez un organisme immature comme c'est le cas chez les nouveau-nés, ces CRL associent apnée, bradycardie, laryngospasme, hypertension et redistribution du débit sanguin. En période néonatale, ces CRL, déclenchés en réponse à un reflux gastro-oesophagien acide, sont t
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6

Mateos, Juan Carlos Pachon. "Estudo comparativo dos parâmetros eletrofisiológicos da estimulação endocárdica septal com a estimulação cardíaca endocárdica convencional." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/98/98131/tde-12062012-074413/.

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Fundamento: A estimulação endocárdica convencional do ventrículo direito em ápice ou na região subtricuspídea ocasiona grande alargamento do QRS e importante dessincronização do miocárdio comprometendo a função ventricular. Com o surgimento da estimulação bifocal do VD e com a necessidade de estimulação cardíaca menos deletéria, a estimulação septal do VD tem sido cada vez mais utilizada. Eventualmente têm sido relatados limiares de estimulação mais altos e ondas R menores na estimulação septal. Objetivo: Comparar os parâmetros eletrofisiológicos das estimulações apical e septal, no mesmo paci
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7

Lindholm, Peter. "Severe hypoxemia during apnea in humans : influence of cardiovascular responses /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-314-7/.

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8

Mosca, Nancy Walsh. "Holding premature infants during gavage feeding: Effect on apnea, bradycardia, oxygenation, gastric residual, gastrin, and behavioral state." Case Western Reserve University School of Graduate Studies / OhioLINK, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=case1057766341.

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9

Montazeri, Ghahjaverestan Nasim. "Early detection of cardiac arrhythmia based on Bayesian methods from ECG data." Thesis, Rennes 1, 2015. http://www.theses.fr/2015REN1S061/document.

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L'apnée est une complication fréquente chez les nouveaux-nés prématurés. L'un des problèmes les plus fréquents est l'épisode d'apnée bradycardie dont la répétition influence de manière négative le développement de l'enfant. C'est pourquoi les enfants prématurés sont surveillés en continu par un système de monitoring. Depuis la mise en place de ce système, l'espérance de vie et le pronostic de vie des prématurés ont été considérablement améliorés et ainsi la mortalité réduite. En effet, les avancées technologiques en électronique, informatique et télécommunications ont conduit à l'élaboration d
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10

Wung, Shu-Fen. "Bradyarrhythmias: Clinical Presentation, Diagnosis, and Management." W B SAUNDERS CO-ELSEVIER INC, 2016. http://hdl.handle.net/10150/621215.

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Bradyarrhythmias are common clinical findings consisting of physiologic and pathologic conditions (sinus node dysfunction and atrioventricular [AV] conduction disturbances). Bradyarrhythmias can be benign, requiring no treatment; however, acute unstable bradycardia can lead to cardiac arrest. In patients with confirmed or suspected bradycardia, a thorough history and physical examination should include possible causes of sinoatrial node dysfunction or AV block. Management of bradycardia is based on the severity of symptoms, the underlying causes, presence of potentially reversible causes, pres
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11

Yang, Fan. "Amylin mediates brainstem control of heart rate in the diving reflex." Diss., Temple University Libraries, 2012. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/193415.

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Pharmacology<br>Ph.D.<br>Amylin, or islet amyloid polypeptide is a 37-amino acid member of the calcitonin peptide family. Amylin role in the brainstem and its function in regulating heart rates is unknown. The diving reflex is a powerful autonomic reflex, however no neuropeptides have been described to modulate its function. In this thesis study, amylin expression in the brainstem involving pathways between the trigeminal ganglion and the nucleus ambiguus was visualized and characterized using immunohistochemistry. Its functional role in slowing heart rate and also its involvement in the divin
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12

Furtado, Fabiola Fialho. "Efeitos cardiovasculares induzidos por um novo doador de óxido nítrico, o nitrato tetrahidrofurfurílico (NTHF), em ratos." Universidade Federal da Paraí­ba, 2014. http://tede.biblioteca.ufpb.br:8080/handle/tede/6808.

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Made available in DSpace on 2015-05-14T12:59:58Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 4258055 bytes, checksum: ee74f99507084e08e3e09b960fa1630d (MD5) Previous issue date: 2014-03-04<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Previous studies have show that the organic nitrate tetrahydrofurfuryl (NTHF) induces vasorelaxation in mesenteric artery rings with involvement of the NO-sGC-PKG pathway. This study evaluated the action of NTHF on cardiovascular parameters in spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, investigating: the nitric oxide (NO
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13

Williamson, Allan John. "Cardiovascular effects of a low and a high dose of fentanyl in the isoflurane anesthetized dog: the influence of the anesthetic-sparing effect and the correction of bradycardia." Thesis, Virginia Tech, 2017. http://hdl.handle.net/10919/86614.

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Fentanyl has historically been used to reduce inhalant anesthetic requirements in the dog, with the end goal of reducing detrimental cardiovascular effects seen with their use. While fentanyl has been investigated in this context with the older agent enflurane, this agent is no longer in common use. In the current literature, no studies exist that compare the effects of low and high doses of fentanyl on cardiovascular function in dogs anesthetized with isoflurane. In previous literature, a high dose of fentanyl improved cardiovascular function in enflurane anesthetized dogs only following corr
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14

Sunti, Daniele Martinez de. "Efeitos da abolição da bradicardia reflexa nas respostas cardiorrespiratórias de tambaqui, Colossoma macropomum (Cuvier, 1818), em hipóxia severa: vagotomia versus inibição farmacológica." Universidade Federal de São Carlos, 2013. https://repositorio.ufscar.br/handle/ufscar/1358.

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Made available in DSpace on 2016-06-02T19:22:59Z (GMT). No. of bitstreams: 1 5375.pdf: 1850581 bytes, checksum: 822cefb40c25ca3fd51f51b23edfe47b (MD5) Previous issue date: 2013-06-14<br>Universidade Federal de Sao Carlos<br>Hypoxic bradycardia is a reflex response to hypoxia observed in most fish species studied so far. This reflex is initiated by the stimulation of O2 chemoreceptors and induced by an increase in the inhibitory vagal tonus. Despite of being well described and characterized, the hypothesis that hypoxic bradycardia improves the O2 transference from the ventilatory water to the
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15

Silva, Maria do Socorro de França. "Avaliação dos efeitos do 2-nitrato-1,3- dibutoxipropano (NDBP) sobre o sistema cardiovascular." Universidade Federal da Paraí­ba, 2012. http://tede.biblioteca.ufpb.br:8080/handle/tede/6741.

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Made available in DSpace on 2015-05-14T12:59:38Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 2427284 bytes, checksum: d24742c1a3622f9b0122565e2537caa8 (MD5) Previous issue date: 2012-08-03<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Previous studies have shown that the 2-nitrate-1,3-dibuthoxypropan (NDBP), an organic nitrate synthesized from glycerin, induced vasorelaxation in mesenteric artery of rats through activation of the NO-cGMP-PKG pathway and K+ channels, in addition, caused hypotension and bradycardia in normotensive conscious rats. The current research aime
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16

Souza, Kleber Oliveira de. "Estimulação cardíaca artificial septal versus estimulação apical: estudo comparativo dos parâmetros ecocardiográficos de sincronia cardíaca." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/98/98131/tde-06092018-150600/.

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INTRODUÇÃO: A estimulação cardíaca artificial convencional em ponta do ventrículo direito é o tratamento de eleição para os quadros de bradicardia severa, contudo, apesar de excelente para corrigir a frequência cardíaca, favorece o surgimento de dissincronia ventricular mecânica, podendo agravar ou originar insuficiência cardíaca. Neste contexto, desde a década de 90 são utilizadas no Instituto Dante Pazzanese as estimulações septal (ou para-Hissiana) e bifocal de ventrículo direito (septal e apical). Postula-se que a estimulação em posição septal teria melhores resultados tanto em termos clín
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17

Belão, Thiago de Campos. "Respostas cardiorrespiratórias do teleósteo de respiração aérea, Clarias gariepinus, exposto à hipóxia gradual." Universidade Federal de São Carlos, 2010. https://repositorio.ufscar.br/handle/ufscar/1325.

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Made available in DSpace on 2016-06-02T19:22:53Z (GMT). No. of bitstreams: 1 3162.pdf: 1363154 bytes, checksum: 725b7e9d57697bbcc0ab7a78df25145a (MD5) Previous issue date: 2010-06-25<br>Financiadora de Estudos e Projetos<br>Air-breathing fish are classified as obligatory (when breathing obligatory atmospheric air independently of the water O2 tension) or facultative air-breather (using an air breathing organ ABO -, when theirs gills are not able to extract all O2 necessary to maintain the aerobic mechanisms under hypoxic conditions). The catfish, Clarias gariepinus, is airbreathing fish th
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18

FERRARO, GENEVIEVE. "Bradycardie sinusale spontanee : interet de la denervation pharmacologique." Angers, 1990. http://www.theses.fr/1990ANGE1078.

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19

Bičiště, Jan. "Umělá aorta pro demonstraci činnosti intraaortální balonkové kontrapulzace." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2009. http://www.nusl.cz/ntk/nusl-218047.

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This dissertation work describes design and construction of simulated aorta device intended to demonstrate performance of the intra-aortal balloon catheter (IAB), and to test reaction of the contra-pulsation pump during simulated cardiac output in conditions of tachycardia, bradycardia and arrhythmia. The major part of the device is transparent plastic tube. The pressure pulses (waves) are generated inside this plastic tube to simulate real cardiac output. These pressure pulses are generated by step motor with membrane. The step motor is controlled by programmable control system AMiNi-E. Indiv
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20

Montiel, Christophe Amiouni Elias. "Apnée sportive influence des techniques de compensation sur la bradycardie d'immersion /." [S.l.] : [s.n.], 2006. http://theses.univ-nantes.fr/thesemed/MEDmontiel.pdf.

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21

Traboulsie, Achraf. "Etude de la spécificité pharmacologique et de l'impact physiologique des canaux T." Montpellier 1, 2006. http://www.theses.fr/2006MON13513.

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Les canaux calciques à bas seuil d'activation ou de type T (canaux T) sont impliqués dans plusieurs fonctions physiologiques telles que l'activité pacemaker cardiaque, l'excitabilité neuronale, la sécrétion, la fécondation. . . Le courant calcique correspondant est caractérisé par une activation et une inactivation transitoire (T), une déactivation lente et une faible conductance. Trois sous-unités codant pour les canaux T ont été récemment clonées : α1G, α1H et α1I. Ces canaux n'ont malheureusement pas une pharmacologie spécifique. L'objectif de ma thèse a été de caractériser le rôle de canau
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22

ROUGEOT, VERONIQUE. "Bradycardies et arrets cardiaques au cours des crises d'epilepsie." Université Louis Pasteur (Strasbourg) (1971-2008), 1992. http://www.theses.fr/1992STR1M101.

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23

Azevedo, Luciene Ferreira. "Adaptações autonômicas e cardiovasculares em atletas de alto rendimento: influência da modalidade e periodização do treinamento físico." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-01122011-151729/.

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INTRODUÇÃO: O treinamento físico provoca adaptações cardiovasculares, sendo que maiores adaptações estruturais cardíacas são observadas em atletas de elite, que realizam treinamento físico de alta intensidade com o objetivo de aumento no rendimento. Além disto, atletas apresentam diminuição da frequência cardíaca de repouso, embora os mecanismos que explicam a bradicardia em atletas ainda são controversos. O nível das adaptações pode variar e fatores como o tipo de modalidade esportiva, tempo e nível de treinamento físico podem contribuir para tal variação. Desta forma, o objetivo deste estudo
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24

Leoni, Anne-Laure Escande Denis. "Modèles murins en rythmologie expérimentale." [S.l.] : [s.n.], 2006. http://castore.univ-nantes.fr/castore/GetOAIRef?idDoc=38466.

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25

MESSAGER, PASCALE. "De la stimulation cardiaque temporaire non invasive en urgence : dix exemples d'utilisation au centre hospitalier de senlis." Amiens, 1993. http://www.theses.fr/1993AMIEM049.

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26

Altuve, Miguel. "Détection multivariée des épisodes d'apnée-bradycardie chez le prématuré par modèles semi-markovien cachés." Rennes 1, 2011. http://www.theses.fr/2011REN1S053.

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Cette thèse a comme domaine applicatif la détection précoce des événements d'apnée-bradycardie (AB) chez le prématuré. Après avoir situé l'importance sur le plan clinique de la détection des AB, une démarche méthodologique est proposée. Elle s'appuie sur un processus de fouille de données qui inclut le nettoyage et l'extraction de caractéristiques. Au chapitre 3, une méthode originale à base d'algorithmes évolutionnaires, pour optimiser des seuils et fenêtres d'analyse, est proposée pour adapter les algorithmes de traitement du signal ECG aux caractéristiques spécifiques du prématuré, très dif
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Leoni, Anne-Laure. "Modèles murins en rythmologie expérimentale." Nantes, 2006. http://archive.bu.univ-nantes.fr/pollux/show.action?id=538b454d-5553-4cc8-8af0-c8f22d052097.

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L’activité électrique cardiaque prend naissance dans le nœud sinusal et se propage au myocarde contractile grâce au tissu de conduction. Le travail exposé dans cette thèse démontre le rôle de deux sous-unités de canaux ioniques dans l’automatisme des cellules sinusales et la conduction de l’influx électrique dans le cœur, grâce à l’utilisation de modèles murins. Le premier confirme in vivo l’hypothèse selon laquelle le canal calcique de type T, Cav3. 1, participe à l’automatisme du nœud sinusal et démontre son implication dans la conduction auriculo-ventriculaire (AV) de l’influx électrique. D
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Beuchée, Alain. "Intérêt de l'analyse de la variabilité du rythme cardiaque en néonatalogie : comportement des systèmes de régulation cardiovasculaire dans le syndrome apnée/bradycardie du nouveau-né." Rennes 1, 2005. http://www.theses.fr/2005REN1B090.

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Sont présentés les résultats d'études expérimentales de modulation ou stimulation du système nerveux autonome de façon à reproduire les mécanismes potentiellement impliqués dans la survenue de bradycardies chez le nouveau-né. Le comportement du système nerveux autonome et de la fréquence cardiaque a été analysé en situation de stress chez l'animal immature. Il a été mis en évidence une relation causale entre une stimulation sympato-vagale et l'aspect "complexe" le l'organisation spatiale des RR successifs, l'augmentation de LF et HF, et la baisse de LF/HF en "miroir" de l'augmentation de RR. C
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GORJUX, SYLVIANE. "Etude des fratries de mort subite du nourrisson par triple exploration : holter, phmetrie oesophagienne, polygraphie du sommeil ; a propos de 175 cas." Aix-Marseille 2, 1994. http://www.theses.fr/1994AIX20153.

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Alaoui, Katim. "Contribution à l'étude des effets cardiovasculaires des agonistes dopaminergiques et de leurs mécanismes d'action chez le rat." Bordeaux 2, 1989. http://www.theses.fr/1989BOR2B002.

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31

Chung, You Chong Antony. "Normalisation de la fréquence cardiaque et de la conduction auriculo-ventriculaire dans des modèles de bradycardie congénitale par l'inhibition pharmacologique du courant IkACh." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTT002/document.

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Correction de la bradycardie et des troubles de conduction dans des modèles de dysfonction congénitale de l’automatisme cardiaque par l’inhibition pharmacologique du courant IKAChLa dysfonction du nœud sinusal (DNS) est l’une des principales pathologies de l’automatisme cardiaque. La DNS désigne une multitude de troubles caractérisées par l’incapacité du nœud sinusal (SAN) à générer ou à conduire l’impulsion cardiaque. La seule thérapie actuellement disponible pour la DNS est l’implantation d’un pacemaker électronique. Des études épidémiologiques prévoient un besoin croissant d’implantation de
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Lahlou, Saad Mohamed. "Étude fonctionnelle de l'hypersensibilité du système dopaminergique spinal chez le rat vigile." Université Joseph Fourier (Grenoble), 1990. http://www.theses.fr/1990GRE18008.

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Toader, Emil-Codrut. "Activation parasympathique centrale mise en évidence par enregistrement des motoneurones cardiaques vagaux chez le rat." Lyon 1, 2008. http://tel.archives-ouvertes.fr/docs/00/29/10/46/PDF/ToaderE_08.pdf.

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L’innervation parasympathique du cœur est responsable de la régulation à court terme de la pression artérielle (PA), par le biais du contrôle battement par battement de la fréquence cardiaque. Une diminution de l’activité vagale est considérée comme indice de mauvais pronostic. La projection vagale du noyau ambigu sur le cœur constitue un chemin commun pour le baroréflexe cardiaque et le chemoreflexe de von Bezold Jarisch (BJ). Des mises au point récentes des techniques d’enregistrement extracellulaire des motoneurones cardiaques vagaux (CVM) chez le rat ont rendu un peu plus aisé l’exploratio
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Lopes, Paulo Ricardo. "Efeitos cardiovasculares induzidos pela administração crônica de ativador da enzima conversora de angiotensina 2 associada ao exercício aeróbio em ratos espontaneamente hipertensos." Universidade Federal de Goiás, 2016. http://repositorio.bc.ufg.br/tede/handle/tede/8114.

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Netzer, Florence. "Contrôle des réflexes cardiovasculaires pendant la réaction de défense : rôle du noyau cunéiformis et des neurones sérotoninergiques bulbaires." Paris 5, 2009. http://www.theses.fr/2009PA05P645.

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L’homéostasie cardiovasculaire est maintenue par un ensemble de réflexes (le baroréflexe, le réflexe de Bezold-Jarisch et le chémoréflexe) qui induisent une bradycardie, modulées en fonction des conditions environnementales. En effet, les conduites de fuite ou d’attaque, déclenchées en réponse à certains stimuli stressant (la réaction de défense), s’accompagnent d’une inhibition de la bradycardie du baroréflexe. Chez le rat anesthésié, nous avons montré que la bradycardie du réflexe de Bezold-Jarisch et du chémoréflexe étaient aussi inhibées pendant la réaction de défense, cette inhibition éta
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Toader, Emil. "Activation parasympathique centrale mise en évidence par enregistrement des motoneurones cardiaques vagaux chez le rat." Phd thesis, Université Claude Bernard - Lyon I, 2008. http://tel.archives-ouvertes.fr/tel-00291046.

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L'innervation parasympathique du cœur est responsable de la régulation à court terme de la pression artérielle (PA), par le biais du contrôle battement par battement de la fréquence cardiaque. Une diminution de l'activité vagale est considérée comme indice de mauvais pronostic. La projection vagale du noyau ambigu sur le cœur constitue un chemin commun pour le baroréflexe cardiaque et le chemoreflexe de von Bezold Jarisch (BJ). Des mises au point récentes des techniques d'enregistrement extracellulaire des motoneurones cardiaques vagaux (CVM) chez le rat ont rendu un peu plus aisé l'exploratio
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(6861473), Hung-Chun Lin. "Incidence of Bradycardia, Hypotension, Bradycardia with Hypotension and Their Risk Factors in Dogs Undergoing General Anesthesia." Thesis, 2019.

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<div><b>Background:</b> Bradycardia and hypotension are complications commonly occurring during general anesthesia in small animals. Intraoperative hypotension has been found to be associated with adverse postoperative consequences. </div><div><br></div><div><b>Objectives: </b>The objectives of his study were first, to determine the incidence of bradycardia, hypotension, and bradycardia with hypotension in dogs undergoing general anesthesia, and second, to identify the risk factors associated with these three complications. The third objective was to evaluate the relationship between these thr
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38

Hsueh, Chia-Hsiang, and 薛嘉祥. "Genetic Analysis of Patients with Bradycardia." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/83932089035115407324.

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碩士<br>國立臺灣大學<br>藥理學研究所<br>92<br>Background Cardiac bradyarrhythmia is commonly seen in elderly people. It causes symptoms of fatigue, dizzness, fainting, or even sudden death. Pathological bradycardia is usually caused by sick sinus syndrome and/or AV block. Familial sick sinus syndrome and AV block have been reported. Genetic influence on bradycardia has also been confirmed in twin studies. It is generally believed that there are some genetic factors contributing to the pathogenesis of bradyarrhythmias.. Patients and Methods In this report, we performed an association study to search for pos
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Smith-White, Margaret A. "A functional study of neuropeptide Y mediated attenuation of vagal-evoked bradycardia /." 2003. http://www.library.unsw.edu.au/~thesis/adt-NUN/public/adt-NUN20031028.105649/index.html.

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40

"Computational Challenges in Non-parametric Prediction of Bradycardia in Preterm Infants." Master's thesis, 2020. http://hdl.handle.net/2286/R.I.63054.

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abstract: Infants born before 37 weeks of pregnancy are considered to be preterm. Typically, preterm infants have to be strictly monitored since they are highly susceptible to health problems like hypoxemia (low blood oxygen level), apnea, respiratory issues, cardiac problems, neurological problems as well as an increased chance of long-term health issues such as cerebral palsy, asthma and sudden infant death syndrome. One of the leading health complications in preterm infants is bradycardia - which is defined as the slower than expected heart rate, generally beating lower than 60 beats per mi
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Sievers, Jule [Verfasser]. "Effect of four different nasal ventilation and CPAP systems on bradycardia and desaturation events in preterm infants / vorgelegt von Jule Sievers." 2008. http://d-nb.info/994121962/34.

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42

Cadete, Rúben Alexandre Monteiro Pereira Parreira. "Impact of the Lockdown for COVID19 in the Urgent Pacemaker Implantations." Master's thesis, 2021. http://hdl.handle.net/10316/98432.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introduction: COVID-19 was first considered a pandemic on the 11th of March of 2020 by the World Health Organization. Its impact comprised, not only the direct consequences of the disease, but also a decrease in the follow-up and interventions of patients with cardiovascular (CV) disease. In Portugal, the consequences of this complex paradigm shift on emergent pacemaker implantation rates during and after this pandemic is largely unknown. Methods: In this retrospective observational study, we included 180 p
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43

Tanguay, Jeremie. "Identifications des interactions des inhibiteurs connus des canaux HCNs." Thesis, 2018. http://hdl.handle.net/1866/24378.

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Les canaux activés par l’hyperpolarisation et sensibles aux nucléotides cycliques (hy- perpolarization cyclic nucleotide-gated channel; HCN) ont un rôle dans la régulation du rythme cardiaque ainsi que dans la transmission des influx nerveux. De nombreuses pathologies sont causées par un disfonctionnement de ces canaux. A ce jour, Ivabradine représente la seule molécule utilisée comme médicament, mais malgré sa spécificité en- vers les canaux HCNs, elle n’est pas sélective entre les isoformes de la famille HCN. Dans le but d’identifier une molécule plus adéquate pour le traitement qu’Ivabradin
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Lajiness, Jacquelyn D. "Shp2 deletion in post-migratory neural crest cells results in impaired cardiac sympathetic innervation." Thesis, 2014. http://hdl.handle.net/1805/5495.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Autonomic innervation of the heart begins in utero and continues during the neonatal phase of life. A balance between the sympathetic and parasympathetic arms of the autonomic nervous system is required to regulate heart rate as well as the force of each contraction. Our lab studies the development of sympathetic innervation of the early postnatal heart in a conditional knockout (cKO) of Src homology protein tyrosine phosphatase 2 (Shp2). Shp2 is a ubiquitously expressed non-receptor phosphatase involved in a variety of cellular func
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Duverger, James Elber. "Stimulateur cardiaque biologique : effets de la répartition spatiale des cardiomyocytes avec activité spontanée et de l'étirement uniaxial." Thèse, 2017. http://hdl.handle.net/1866/20268.

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46

FANG, TONG-JING, and 房同經. "Central actions of vasopressin, angiotensin and catecholamines on the barore flex bradycardic response." Thesis, 1985. http://ndltd.ncl.edu.tw/handle/11456554448325013826.

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47

Kočková, Radka. "Vliv positivně inotropních a antiarytmických farmak na kardiovaskulární systém." Doctoral thesis, 2015. http://www.nusl.cz/ntk/nusl-333581.

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Heart rate changes mediate the embryotoxic effect of antiarrhythmic drugs in the chick embryo A significant increase in cardiovascular medication use during pregnancy has occurred in recent years but only limited evidence on its safety profile is available. We hypothesized that drug-induced bradycardia is the leading mechanism of developmental toxicity. We tested metoprolol, carvedilol, or ivabradine for embryotoxicity and their acute effect on chick embryonic model. We used video microscopy and ultrasound biomicroscopy. Significant dose-dependent mortality was achieved in embryos injected wit
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(9178664), Maria I. Muzquiz, and Ivette M. Muzquiz (9178658). "Reversible Nerve Conduction Block Using Low Frequency Alternating Currents." Thesis, 2020.

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This thesis describes a novel method to reversibly and safely block nerve conduction using a low frequency alternating current (LFAC) waveform at 1 Hz applied through a bipolar extrafascicular electrode. This work follows up on observations made on excised mammalian peripheral nerves and earthworm nerve cords. An<i> in-situ</i> electrophysiology setup was used to assess the LFAC<br>waveform on propagating action potentials (APs) within the cervical vagus nerve in anaesthetized Sprague-Dawley rats (n = 12). Two sets of bipolar cuff or hook electrodes were applied unilaterally to the cervical va
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