Academic literature on the topic 'Brain Alcoholism Alcohol'

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Journal articles on the topic "Brain Alcoholism Alcohol"

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Lishman, W. A. "Alcohol and the Brain." British Journal of Psychiatry 156, no. 5 (1990): 635–44. http://dx.doi.org/10.1192/bjp.156.5.635.

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Some of the major effects of alcohol, and alcoholism, on the brain are reviewed, with reappraisal of evidence drawn from brain imaging, neuropathology, clinical psychology, and laboratory experimental work. A hypothesis is developed which may help to account for the wide variability encountered in individual susceptibility to alcoholic brain damage and its varied manifestations. Therapeutic implications are considered.
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Le Berre, A. P., G. Rauchs, R. La Joie, et al. "Impaired decision-making and brain shrinkage in alcoholism." European Psychiatry 29, no. 3 (2014): 125–33. http://dx.doi.org/10.1016/j.eurpsy.2012.10.002.

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AbstractAlcohol-dependent individuals usually favor instant gratification of alcohol use and ignore its long-term negative consequences, reflecting impaired decision-making. According to the somatic marker hypothesis, decision-making abilities are subtended by an extended brain network. As chronic alcohol consumption is known to be associated with brain shrinkage in this network, the present study investigated relationships between brain shrinkage and decision-making impairments in alcohol-dependent individuals early in abstinence using voxel-based morphometry. Thirty patients performed the Io
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Kashem, Mohammed Abul, Omar Šerý, David V. Pow, Benjamin D. Rowlands, Caroline D. Rae, and Vladimir J. Balcar. "Actions of Alcohol in Brain: Genetics, Metabolomics, GABA Receptors, Proteomics and Glutamate Transporter GLAST/EAAT1." Current Molecular Pharmacology 14, no. 2 (2020): 138–49. http://dx.doi.org/10.2174/1874467213666200424155244.

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We present an overview of genetic, metabolomic, proteomic and neurochemical studies done mainly in our laboratories that could improve prediction, mechanistic understanding and possibly extend to diagnostics and treatment of alcoholism and alcohol addiction. Specific polymorphisms in genes encoding for interleukins 2 and 6, catechol-O-methyl transferase (COMT), monaminooxidase B (MAO B) and several other enzymes were identified as associated with altered risks of alcoholism in humans. A polymorphism in the gene for BDNF has been linked to the risk of developing deficiences in colour vision som
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Ragan, Paul W., Charles K. Singleton, and Peter R. Martin. "Brain Injury Associated With Chronic Alcoholism." CNS Spectrums 4, no. 1 (1999): 66–68. http://dx.doi.org/10.1017/s1092852900011226.

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AbstractAlcoholism can result in a number of severe consequences to the central nervous system, including Korsakoff's psychosis, delusions, delirium, Wernicke's encephalopathy, and cerebellar degeneration. Many of these disorders have a substantially higher prevalence than had been previously believed. Neuropathologic and neuroimaging studies have been instrumental in identifying the changes undergone by the alcoholic brain and the factors that may contribute to alcohol-induced brain damage. Biologic differences appear to make women especially susceptible to central nervous system insult from
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Hayakawa, K., H. Kumagai, Y. Suzuki, et al. "Mr Imaging of Chronic Alcoholism." Acta Radiologica 33, no. 3 (1992): 201–6. http://dx.doi.org/10.1177/028418519203300302.

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We evaluated the brain lesions of patients with chronic alcoholism (n = 34) in comparison with age- and sex-matched controls (n = 40) by MR imaging. T1-weighted sagittal and axial images and T2-weighted axial images were obtained with a 0.5 T superconducting MR unit. Various brain measurements were then performed, and the presence of regions of abnormal signal intensity was also compared between the two groups. The brain measurements revealed significant cerebral atrophy (characterized by lateral and 3rd ventricular dilatation, and widening of the interhemispheric fissure) as well as significa
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Shri, T. K. Padma, and N. Sriraam. "EEG Based Detection of Alcoholics." International Journal of Biomedical and Clinical Engineering 1, no. 1 (2012): 59–76. http://dx.doi.org/10.4018/ijbce.2012010105.

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The short term and long term effects of alcohol on various organs of the body, especially on the human brain is well established by numerous studies. Invasive methods such as Transcranial Magnetic Stimulation (TMS) and non invasive imaging techniques such as Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), and functional MRI activated electro-encephalogram (EEG) have been used to study the changes in EEG activity due to alcoholism. Even with the advent of neuro imaging techniques, EEG happens to be an important tool for brain study providing a non
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Brenner, Eric, Gayatri R. Tiwari, Manav Kapoor, Yunlong Liu, Amy Brock, and R. Dayne Mayfield. "Single cell transcriptome profiling of the human alcohol-dependent brain." Human Molecular Genetics 29, no. 7 (2020): 1144–53. http://dx.doi.org/10.1093/hmg/ddaa038.

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Abstract Alcoholism remains a prevalent health concern throughout the world. Previous studies have identified transcriptomic patterns in the brain associated with alcohol dependence in both humans and animal models. But none of these studies have systematically investigated expression within the unique cell types present in the brain. We utilized single nucleus RNA sequencing (snRNA-seq) to examine the transcriptomes of over 16 000 nuclei isolated from the prefrontal cortex of alcoholic and control individuals. Each nucleus was assigned to one of seven major cell types by unsupervised clusteri
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Kuruoglu, Asli Çepik, Zehra Arikan, Gülin Vural, Metin Karataş, Mehmet Araç, and Erdal Işik. "Single Photon Emission Computerised Tomography in Chronic Alcoholism." British Journal of Psychiatry 169, no. 3 (1996): 348–54. http://dx.doi.org/10.1192/bjp.169.3.348.

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BackgroundWe examined the functional and structural cerebral changes in chronic alcoholics, analysing their association with personality features and alcohol drinking habits.MethodForty patients with alcohol dependency, including 15 with antisocial personality disorder (ASP) as defined in DSM–III–R and 10 age and sex matched healthy controls were studied after termination of withdrawal symptoms, using high resolution single photon emission tomography (SPECT), cranial computerised tomography (CT) and brainstem auditory evoked potentials (BAEP).ResultsWe found significant reductions in regional
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Jacobson, R. R., and W. A. Lishman. "Cortical and diencephalic lesions in Korsakoff's syndrome: a clinical and scan study." Psychological Medicine 20, no. 1 (1990): 63–75. http://dx.doi.org/10.1017/s0033291700013234.

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SYNOPSISTwenty-five male alcoholic Korsakoff patients were compared with age and sex-matched non-Korsakoff chronic alcoholics and healthy volunteers on clinical and CT brain scan parameters. The scans were assessed by planimetry, visual grading procedures and computerized analysis. Reliable measures of third ventricular size were developed.The Korsakoff patients had wider third ventricles, larger lateral ventricles and wider interhemispheric fissures than the comparison groups; but sulcal and Sylvian fissure widths were equivalent in Korsakoff and non-Korsakoff alcoholics.The results suggest t
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Koob, George F., and Amanda J. Roberts. "Brain Reward Circuits in Alcoholism." CNS Spectrums 4, no. 1 (1999): 23–37. http://dx.doi.org/10.1017/s1092852900011196.

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AbstractThis article discusses the neurocircuitry and the neurochemical systems, as well as the molecular elements within these systems, that are believed to be important in the etiology of alcoholism. Alcoholism is a complex behavioral disorder characterized by excessive consumption of alcohol; a narrowing of the behavioral repertoire toward excessive consumption; the development of tolerance and dependence; and impairment in social and occupational functioning. Animal models of the complete syndrome of alcoholism are difficult if not impossible to achieve, but validated animal models exist f
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Dissertations / Theses on the topic "Brain Alcoholism Alcohol"

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Arlinde, Christina. "Gene expression profiling in animal models of alcoholism /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-133-4/.

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van, der Vaart Andrew D. "Molecular Brain Adaptations to Ethanol: Role of Glycogen Synthase Kinase-3 Beta in the Transition to Excessive Consumption." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5510.

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Alcoholism is a complex neuropsychiatric disease that is characterized by compulsive alcohol use and intensifying cravings and withdrawals, often culminating in physiologic dependency. Fundamental alterations in brain chemistry underlie the transition from initial ethanol exposure to repetitive excessive use. Key mediators of this adaptation include changes in gene expression and signal transduction. Here we investigated gene expression pathways in prefrontal cortex and nucleus accumbens following acute or chronic ethanol treatment, to identify genes with potentially conserved involvement in t
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Alexander-Kaufman, Kimberley Louise. "Proteomics of the human alcoholic brain: Implications for the pathophysiology of alcohol-related brain damage." The University of Sydney, 2008. http://hdl.handle.net/2123/2692.

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Doctor of Philosophy (PhD)<br>Proteomics is rapidly achieving recognition as a complimentary and perhaps superior approach to examine global changes in protein abundance in complex biological systems and the value of these techniques in neuropsychiatry is beginning to be acknowledged. Characterizing the brain’s regional proteomes provides a foundation for the detection of proteins that may be involved in disease-related processes. Firstly, optimal conditions were achieved for the application of two dimensional-gel electrophoresis (2D-GE)-based proteomics with postmortem human brain tissue. The
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Hård, Julia. "Långvarigt bruk av alkohol ger kramper och epilepsi : Ett arbete om alkohols effekter på hjärnan." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-65066.

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Alkohol har funnits sedan urminnes tider och är något som de flesta ungdomar och vuxna är bekanta med. Flertalet vet också att för mycket alkohol på lång sikt kan orsaka skador, framförallt på lever (fettlever) och njurar. Men inte alla vet att alkohol skadar hjärnan och kan ge kramper samt epilepsi. Alkohol har olika effekter på kroppen. Akut kan det öka den inhiberande och minska den excitatoriska signaleringen i hjärnan. Långvarigt kan det öka den excitatoriska signaleringen, minska den inhibitoriska samt öka alkoholtoleransen. I hjärnan är balansen mellan den inhibitoriska och excitatorisk
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Buckley, Stella Tracey. "GabaA receptor-mediated neurotransmission in human alcoholic brain /." St. Lucia, Qld, 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17286.pdf.

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Bazov, Igor. "Epigenetic Dysregulations in the Brain of Human Alcoholics : Analysis of Opioid Genes." Doctoral thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-270321.

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Neuropeptides are special in their expression profiles restricted to neuronal subpopulations and low tissue mRNA levels. Genetic, epigenetic and transcriptional mechanisms that define spatiotemporal expression of the neuropeptide genes have utmost importance for the formation and functions of neural circuits in normal and pathological human brain. This thesis focuses on regulation of transcription of the opioid/nociceptin genes, the largest neuropeptide family, and on identification of adaptive changes in these mechanisms associated with alcoholism as model human pathology. Two epigenetic mech
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Roy, Arnab. "Evolving spike neural network based spatio-temporal pattern classifiers with an application to identifying the alcoholic brain." Thesis, State University of New York at Binghamton, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3630956.

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<p> We introduce a novel approach to evolving spike neural network (SNN) based Spatio-temporal (ST) pattern classifiers that can detect occurrences of hidden structures in a ST data. We test this learning paradigm to find characteristic electrical patterns in visually evoked response potentials (VERPs) generated by an alcoholic brain. </p><p> We cast the alcoholic classification task as a multiple feature selection (FS) problem. The FS problems are grouped under 2 classes: the spatial task and the temporal task. The objective of the spatial FS task is to choose a correct subset of electroen
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Troni, Kelly Lendini 1980. "Estudo sobre o uso do resíduo da etapa de deceragem de óleo de farelo de arroz para a produção de ácidos graxos e álcoois graxos." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266628.

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Orientador: Roberta Ceriani<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Química<br>Made available in DSpace on 2018-08-23T01:21:42Z (GMT). No. of bitstreams: 1 Troni_KellyLendini_M.pdf: 3567932 bytes, checksum: fb83c16b04e83a1bcc666f11c5237dec (MD5) Previous issue date: 2013<br>Resumo: A cera do óleo de farelo de arroz (OFA) é um resíduo da etapa de deceragem no processo de refino de óleos. Tradicionalmente, as ceras naturais, que em excesso geram turbidez no óleo vegetal embalado, são removidas por cristalização e filtração a baixa temperatura. Ess
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Berman, Ari Ethan. "Brain region gene expression responds discretely to chronic alcohol withdrawal with specific disruption of the hippocampus during intoxication." Thesis, 2005. http://hdl.handle.net/2152/2686.

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Liu, Jianwen. "Studies of the global gene expression changes in alcoholic human brain and blood." Thesis, 2005. http://hdl.handle.net/2152/2267.

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Books on the topic "Brain Alcoholism Alcohol"

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W, Goedde H., ed. Alcohol metabolism, alcohol intolerance, and alcoholism: Biochemical and pharmacogenetic approaches. Springer-Verlag, 1990.

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Brennfleck, Shannon Joyce, ed. Alcohol information for teens: Health tips about alcohol and alcoholism : including facts about underage drinking, preventing teen alcohol use, alcohol's effects on the brain and the body, alcohol abuse treatment, help for children of alcoholics, and more. Omnigraphics, 2005.

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E, Payne James, ed. Alcohol and the addictive brain: New hope for alcoholics from biogenetic research. Free Press, 1991.

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A, Deitrich Richard, Pawlowski Albert 1925-, National Institute on Alcohol Abuse and Alcoholism (U.S.), and University of Colorado, Boulder. Alcohol Research Center., eds. Initial sensitivity to alcohol: Proceedings of a Workshop on Alcohol Intoxication, October 13-14, 1988, Keystone, Colorado. The Institute, 1990.

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Organisation of goal-directed behaviour: Development of experimental methods and analysis of chronic and acute effects of alcohol on correlations between brain potentials. Universitatis ouluensis, 1994.

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Institute of Medicine (U.S.). Prevention and treatment of alcohol problems: Research opportunities. National Academy Press, 1989.

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International, Symposium for Biomedical Research on Alcoholism (1988 Taipei Taiwan). Molecular mechanisms of alcohol: Neurobiology and metabolism. Humana Press, 1989.

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Parker, Philip M., and James N. Parker. Alcohol addiction: A medical dictionary, bibliography, and annotated research guide to Internet references. ICON Health Publications, 2004.

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Shannon, Joyce Brennfleck. Alcoholism sourcebook: Basic consumer health information about alcohol use, abuse, and addiction, including facts about the physical consequences of alcohol abuse, such as brain changes and problems with cognitive functioning, cirrhosis and other liver diseases, cardiovascular disease, pancreatitis, and alcoholic neuropathy, and the effects of alcohol on reproductive health and fetal development, mental health problems associated with alcohol abuse, and alcohol's impact on families, workplaces, and the community ; along with information about underage drinking, alcohol treatment and recovery, a glossary of related terms, and directories of resources for more information. 3rd ed. Omnigraphics, 2010.

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Nagata, Atsuo. Arukōru no kenkōgaku: Sake o aisuru senmon'i ga oshieru. Kinokuniya Shoten, 1999.

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Book chapters on the topic "Brain Alcoholism Alcohol"

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Antonow, David R., and Craig J. McClain. "Nutrition and Alcoholism." In Alcohol and the Brain. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4757-9134-1_4.

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Tarter, Ralph E., and Kathleen L. Edwards. "Neuropsychology of Alcoholism." In Alcohol and the Brain. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4757-9134-1_8.

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Goldstein, Gerald. "Dementia Associated with Alcoholism." In Alcohol and the Brain. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4757-9134-1_11.

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Wilkinson, D. Adrian. "Neuroradiologic Investigations of Alcoholism." In Alcohol and the Brain. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4757-9134-1_7.

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Badawy, Abdulla A. B. "Liver Tryptophan Pyrrolase, Brain 5-Hydroxytryptamine and Alcohol Preference." In Alcoholism. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-5946-3_23.

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Porjesz, Bernice, and Henri Begleiter. "Human Brain Electrophysiology and Alcoholism." In Alcohol and the Brain. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4757-9134-1_6.

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Fialkov, M. Jerome. "Biologic and Psychosocial Determinants in the Etiology of Alcoholism." In Alcohol and the Brain. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4757-9134-1_9.

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Cala, Lesley Ann. "CT Demonstration of the Early Effects of Alcohol on the Brain." In Recent Developments in Alcoholism. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4615-7715-7_20.

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Vetreno, Ryan P., and Fulton T. Crews. "Innate Immune Signaling and Alcoholism." In Neural-Immune Interactions in Brain Function and Alcohol Related Disorders. Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-4729-0_8.

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Nachiappan, V., K. R. Shanmugasundaram, and S. I. Mufti. "Control of Alcoholism by Treatment with SKV, A Herbal Drug Mixture from India." In Alcohol, Cell Membranes, and Signal Transduction in Brain. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2470-0_17.

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Conference papers on the topic "Brain Alcoholism Alcohol"

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Prabhakar, Sunil Kumar, Harikumar Rajaguru, and Seong-Whan Lee. "A Comprehensive Analysis of Alcoholic EEG Signals with Detrend Fluctuation Analysis and Post Classifiers." In 2019 7th International Winter Conference on Brain-Computer Interface (BCI). IEEE, 2019. http://dx.doi.org/10.1109/iww-bci.2019.8737328.

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Adhikari, Prakash, Pradeep K. Shukla, Radhakrishna Rao, and Prabhakar Pradhan. "Photonics probing of probiotics effect on chronic alcoholic brain cell nuclei using light localization via confocal imaging." In CLEO: Applications and Technology. OSA, 2021. http://dx.doi.org/10.1364/cleo_at.2021.am3c.7.

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Adhikari, Prakash, Pradeep K. Shukla, Radhakrishna Rao, and Prabhakar Pradhan. "Quantification of light localization properties to study the effect of probiotic on chronic alcoholic brain cells via confocal imaging." In Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIX, edited by James F. Leary, Attila Tarnok, and Irene Georgakoudi. SPIE, 2021. http://dx.doi.org/10.1117/12.2578785.

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