Relevant bibliographies by topics / Brain Brain mapping. Rats

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Brain Brain mapping. Rats'

Author: Grafiati
Published: 4 June 2021
Last updated: 19 February 2022

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Journal articles on the topic "Brain Brain mapping. Rats"

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Evans, Brianna Brie, Sarah Ballard, Kyra Newmaster, Yongsoo Kim, and Sue Grigson. "59821 Brain Mapping Addiction." Journal of Clinical and Translational Science 5, s1 (2021): 15–16. http://dx.doi.org/10.1017/cts.2021.443.

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ABSTRACT IMPACT: Gaining a better understanding on the role of opioids in opioid use disorder (OUD) can help us find better diagnostics, treatments, and procedures to treat the disorder. OBJECTIVES/GOALS: While we are familiar with brain areas and pathways that are implicated in opioid use disorder (OUD), we do not have a full understanding of the neural circuits activated upon drug exposure. METHODS/STUDY POPULATION: In order to identify areas of the brain most activated by opioids, we ran a pilot study using transgenic cFos-GFP mice that were injected with saline or heroin and examined the brain-wide activity patterns using a quantitative high-resolution mapping method. We observed many brain regions highly activated upon drug exposure. To examine cFos based brain activation in rats, we also ran a pilot study using a tissue clearing and 3D immunolabeling method combined with light sheet microscopy. RESULTS/ANTICIPATED RESULTS: We would expect to see higher cFos activation for brain areas in the reward pathway [including the Nucleus Accumbens (NAc), Ventral Tegmental Area (VTA), Prefrontal Cortex (PFC)] in heroin animals compared to saline animals. We can also expect higher activation in more novel areas like the lateral hypothalamus. DISCUSSION/SIGNIFICANCE OF FINDINGS: If we are able to track OUD effects through imaging in mice and rats, this can help us find better diagnostics, therapeutics, and procedures to treat the disorder. We can also eventually have a human brain atlas that outlines these affected areas as well in order to gain a better understanding on OUD particularly in the human population.
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Mericle, Robert A., Erich O. Richter, Eric Eskioglu, et al. "Preoperative endovascular brain mapping for intraoperative volumetric image guidance: preliminary concept and feasibility in animal models." Journal of Neurosurgery 104, no. 4 (2006): 566–73. http://dx.doi.org/10.3171/jns.2006.104.4.566.

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ObjectThe authors describe a novel concept for brain mapping in which an endovascular approach is used, and they demonstrate its feasibility in animal models. The purpose of endovascular brain mapping is to delineate clearly the nonfunctional brain parenchyma when a craniotomy is performed for resection. The nonfunctional brain will be stained with sharp visual margins, differentiating it from the functional, nonstained brain. The authors list four essential criteria for developing an ideal endovascular mapping agent, and they describe seven potential approaches for accomplishing a successful endovascular brain map.MethodsFour Sprague–Dawley rats and one New Zealand white rabbit were used to determine initial feasibility of the procedure. The animals were anesthetized, and the internal carotid artery was catheterized. Four potential brain mapping agents were infused into the right hemisphere of the five animals. Afterward, the brains were removed and each was analyzed both grossly and histologically.Fluorescein and FD&C Green No. 3 provided good visual clarity and margins, but required blood–brain barrier (BBB) manipulation. Tantalum particles enabled avoidance of BBB manipulation, but provided inadequate visual clarity, probably because of their size. A Sudan black “cocktail” provided excellent clarity and margins despite remaining in the brain capillaries.ConclusionsThis is a novel application of the endovascular approach, and has broad potential for clinical neurosurgical brain mapping. The animal models in this study establish the feasibility of the procedure. However, further study is required to demonstrate safety, minimize toxicity, investigate stain durability, and improve the characteristics of potential mapping agents. The authors are planning to conduct future studies for identification of mapping agents that do not require BBB manipulation or vascular occlusion.
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Tsurugizawa, Tomokazu, Akira Uematsu, Hisayuki Uneyama, and Kunio Torii. "Functional brain mapping of conscious rats during reward anticipation." Journal of Neuroscience Methods 206, no. 2 (2012): 132–37. http://dx.doi.org/10.1016/j.jneumeth.2012.02.014.

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Manning, H. Charles, Sheila D. Shay, and Robert A. Mericle. "Multispectral molecular imaging of capillary endothelium to facilitate preoperative endovascular brain mapping." Journal of Neurosurgery 110, no. 5 (2009): 975–80. http://dx.doi.org/10.3171/2008.9.jns08420.

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Object Brain mapping aims to localize neurological function to specific regions of the human brain. Preoperative endovascular brain mapping (PEBM) is a novel approach that allows clear visualization of nonfunctional (silent) brain parenchyma in real time during a resection. It has potential to improve neurosurgical guidance because brain shift does not alter the maps, and the map is visualized directly on the brain in situ rather than on a nearby image. Therefore, the risk of a new neurological deficit should be reduced. The authors report the first PEBM approach that combines selective molecular targeting of brain endothelium with multispectral (optical) imaging in preclinical animal models. Methods Sprague-Dawley rats and New Zealand white rabbits were selectively catheterized, and a fluorescein isothiocyanate–derivatized tomato lectin–based imaging probe was administered into the carotid artery or posterior cerebral artery, measuring < 500 μm in diameter. After binding/uptake of the imaging probe, and removal of unbound probe, a craniotomy was performed to directly visualize the “brain map.” Results Selective localization of the imaging probe to the right hemisphere in rats or right posterior cerebral artery in rabbits was clearly visualized after craniotomy. Cross-sections of stained capillaries demonstrated that the imaging probe did not cause vascular occlusion. Gross regional selectivity of the imaging probe was documented by multispectral molecular imaging of intact brains, with discrete localization and endothelium-directed targeting validated by histological examination. Conclusions The authors have demonstrated the first molecular endothelium-targeted approach to PEBM that does not require manipulation of the intact blood-brain barrier or result in vascular occlusion. Furthermore, the presented multispectral molecular imaging technique appears to be a suitable methodology for the generation of region-selective brain maps of vascularized brain parenchyma. Further refinement of the PEBM approach, as well as the development of improved imaging probes, may result in clinical advancement of PEBM where direct visual discrimination of nonfunctional silent brain parenchyma at the time of resection could significantly improve neurosurgical outcomes.
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Holschneider, D. P., J.-M. I. Maarek, J. Yang, J. Harimoto, and O. U. Scremin. "Functional Brain Mapping in Freely Moving Rats during Treadmill Walking." Journal of Cerebral Blood Flow & Metabolism 23, no. 8 (2003): 925–32. http://dx.doi.org/10.1097/01.wcb.0000072797.66873.6a.

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A dilemma in functional neuroimaging is that immobilization of the subject, necessary to avoid movement artifact, extinguishes all but the simplest behaviors. Recently, we developed an implantable microbolus infusion pump (MIP) that allows bolus injection of radiotracers by remote activation in freely moving, nontethered animals. The MIP is examined as a tool for brain mapping in rats during a locomotor task. Cerebral blood flow–related tissue radioactivity (CBF-TR) was measured using [14C]-iodoantipyrine with an indicator-fractionation method, followed by autoradiography. Rats exposed to walking on a treadmill, compared to quiescent controls, showed increases in CBF-TR in motor circuits (primary motor cortex, dorsolateral striatum, ventrolateral thalamus, midline cerebellum, copula pyramis, paramedian lobule), in primary somatosensory cortex mapping the forelimbs, hindlimbs and trunk, as well as in secondary visual cortex. These results support the use of implantable pumps as adjunct tools for functional neuroimaging of behaviors that cannot be elicited in restrained or tethered animals.
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Braidy, Nady, Anne Poljak, Ross Grant, et al. "Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence." Biogerontology 15, no. 2 (2013): 177–98. http://dx.doi.org/10.1007/s10522-013-9489-5.

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Wang, Hao, Qingyuan Zhu, Lufeng Ding, et al. "Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution." National Science Review 6, no. 5 (2019): 982–92. http://dx.doi.org/10.1093/nsr/nwz053.

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Abstract The speed of high-resolution optical imaging has been a rate-limiting factor for meso-scale mapping of brain structures and functional circuits, which is of fundamental importance for neuroscience research. Here, we describe a new microscopy method of Volumetric Imaging with Synchronized on-the-fly-scan and Readout (VISoR) for high-throughput, high-quality brain mapping. Combining synchronized scanning beam illumination and oblique imaging over cleared tissue sections in smooth motion, the VISoR system effectively eliminates motion blur to obtain undistorted images. By continuously imaging moving samples without stopping, the system achieves high-speed 3D image acquisition of an entire mouse brain within 1.5 hours, at a resolution capable of visualizing synaptic spines. A pipeline is developed for sample preparation, imaging, 3D image reconstruction and quantification. Our approach is compatible with immunofluorescence methods, enabling flexible cell-type specific brain mapping and is readily scalable for large biological samples such as primate brains. Using this system, we examined behaviorally relevant whole-brain neuronal activation in 16 c-Fos-shEGFP mice under resting or forced swimming conditions. Our results indicate the involvement of multiple subcortical areas in stress response. Intriguingly, neuronal activation in these areas exhibits striking individual variability among different animals, suggesting the necessity of sufficient cohort size for such studies.
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Nair, Hemanth P., Jason D. Berndt, Douglas Barrett, and F. Gonzalez-Lima. "Metabolic mapping of brain regions associated with behavioral extinction in preweanling rats." Brain Research 903, no. 1-2 (2001): 141–53. http://dx.doi.org/10.1016/s0006-8993(01)02469-6.

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Thanos, P. K., L. Robison, E. J. Nestler, et al. "Mapping Brain Metabolic Connectivity in Awake Rats with PET and Optogenetic Stimulation." Journal of Neuroscience 33, no. 15 (2013): 6343–49. http://dx.doi.org/10.1523/jneurosci.4997-12.2013.

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Shaw, Fu-Zen, Tsung-Fu Yang, Chien-Chun Huang, Keng-Hung Yeh, Tao-Chih Chang, and Fang-Jun Leu. "MULTICHANNEL PLANAR MICROELECTRODE ARRAY FOR SOMATIC MAPPING IN RATS." Biomedical Engineering: Applications, Basis and Communications 23, no. 06 (2011): 501–8. http://dx.doi.org/10.4015/s1016237211002840.

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Planar electrode array is an important tool to evaluate perceptual or cognitive functions of the cortex and prosthetic applications. Many construction methods have been developed. To maximize the usefulness of an array electrode, a low-cost, precise, and flexible microelectrode array with low man power and short construction duration is crucial. In this study, we introduced an 8 × 8 microelectrode array on a flexible polyimide film through microelectronics fabrication. The array dimension was capable of covering the primary somatosensory cortex of a rat. The microelectrode array was insulated with biocompatible Parylene-C except of microelectrode tip. Each electrode tip was 66 μm height and separated with 0.5 mm to refine a detail somatic sensory processing. In pentobarbital anesthetized rats, stable spontaneous brain activity was successfully recorded through the electrode array. In addition, positive peaks of somatosensory evoked potentials (SEPs) elicited by stimulating rat's whisker pad, forepaw, hindpaw, and tail were obviously and consistently recorded. Latencies of SEPs increased as caudal part of the body was stimulated. The SEPs from stimulation of 4 body parts revealed different spatiotemporal patterns, which indicated a somatotopic organization of the rat. Our results demonstrated the superiority of the planar microelectrode array on the application of simultaneous recording and analysis of the brain activity in rats.
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Dissertations / Theses on the topic "Brain Brain mapping. Rats"

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Majeed, Waqas. "Spatiotemporal dynamics of low frequency fluctuations in bold fMRI." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/37116.

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Traditional fMRI utilizes blood oxygenation level dependent (BOLD) contrast to map brain activity. BOLD signal is sensitive to the hemodynamic changes associated with brain activity, and gives an indirect measure of brain activity. Low frequency fluctuations (LFFs) have been observed in the BOLD signal even in the absence of any anesthetic agent, and the correlations between the fluctuations from different brain regions has been used to map functional connectivity in the brain. Most studies involving spontaneous fluctuations in the BOLD signal extract connectivity patterns that show relationships between brain areas that are maintained over the length of the scanning session. The research presented in this document investigates the spatiotemporal dynamics of the BOLD fluctuations to identify common spatiotemporal patterns within a scan. First, the presence of a visually detectable spatiotemporal propagation pattern is demonstrated by utilizing single-slice data with high spatial and temporal resolution. The pattern consists of lateral-medial propagation of BOLD signal, demonstrating the presence of time-varying features in spontaneous BOLD fluctuations. Further, a novel pattern finding algorithm is developed for detecting repeated spatiotemporal patterns in BOLD fMRI data. The algorithm is applied to high temporal resolution T2*-weighted multislice images obtained from rats and humans in the absence of any task or stimulation. In rats, the primary pattern consists of waves of high signal intensity, propagating in a lateral-medial direction across the cortex, replicating the results obtained using visual observation. In humans, the most common spatiotemporal pattern consisted of an alteration between activation of areas comprising the "default-mode" (e.g., posterior cingulate and anterior medial prefrontal cortices) and the "task-positive" (e.g., superior parietal and premotor cortices) networks. Signal propagation from focal starting points is also observed. The pattern finding algorithm is shown to be reasonably insensitive to the variation in user-defined parameters, and the results are consistent within and between subjects. This novel approach for probing the spontaneous network activity of the brain has implications for the interpretation of conventional functional connectivity studies, and may increase the amount of information that can be obtained from neuroimaging data.
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Vescovi, Rafael Ferreira da Costa 1989. "Extended tomography : from basics to mapping mouse brains = Tomografia estendida: do básico até o mapeamento de cérebro de camundongos." [s.n.], 2017. http://repositorio.unicamp.br/jspui/handle/REPOSIP/332156.

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Orientador: Mateus Borba Cardoso<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Física Gleb Wataghin<br>Made available in DSpace on 2018-09-05T14:11:53Z (GMT). No. of bitstreams: 1 Vescovi_RafaelFerreiraDaCosta_D.pdf: 72387058 bytes, checksum: 728a9ca57a44975a0fbb2f766a7bbd5c (MD5) Previous issue date: 2017<br>Resumo: Esta tese apresentará uma introdução a imagens de raios-x e como adquirir e processar imagens usando linhas de luz síncrotron. Apresentará os desafios matemáticos e técnicos para reconstruir amostras em três dimensões usando a reconstrução de Tomografia Computadorizada, uma técnica conhecida como CT. Esta técnica tem seu campo de visão limitado ao tamanho da câmera e ao tamanho da iluminação. Uma técnica para ampliar esse campo de visão vai ser apresentada e os desafios técnicos envolvidos para que isso aconteça. Um \textit{pipeline} é proposto e todos os algoritmos necessários foram empacotados em um pacote python chamado Tomosaic. A abordagem baseia-se em adquirir tomogramas parciais em posiçoes pré definidas e depois mesclar os dados em um novo conjunto de dados. Duas maneiras possíveis são apresentadas para essa mescla, uma no domínio das projeções e uma no domínio dos sinogramas. Experimentos iniciais serão então usadas para mostrar que o método proposto funciona com computadores normais. A técnica será aplicada mais tarde para pesquisar a anatomia de cérebros de camundongo completos. Um estudo será apresentado de como obter informação em diferentes escalas do cérebro completo do rato utilizando raios-x<br>Abstract: This thesis will present an introduction to x-ray images and how to acquire and thread images using synchrotron beamlines. It will present the mathematical and technical challenges to reconstruct samples in three dimensions using Computed Tomography reconstruction, a technique known as CT. This technique has a field of view bounded to the camera size and the illumination size. A technique to extended this field of view is going to be presented and the technical challenges involved in order for that to happen will be described. A pipeline is proposed and all the necessary algorithms are contained into a python packaged called Tomosaic. The approach relies on acquired partial tomogram data in a defined grid and later merging the data into a new dataset. Two possible ways are presented in order to that: in the projection domain, and in the sinogram domain. Initial experiments will then be used to show that the pipeline works with normal computers. The technique will be later applied to survey the whole anatomy of whole mouse brains. A study will be shown of how to get the complete range of scales of the mouse brain using x-ray tomography at different resolutions<br>Doutorado<br>Física<br>Doutor em Ciências<br>163304/2013-0<br>1247445/2013, 1456912/2014<br>CNPQ<br>CAPES
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Varotto, Bruna Luiza Roim. "Avaliação da sensibilidade mecânica, ansiedade e neuroplasticidade cortical motora em ratos submetidos à doença periodontal experimental." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5138/tde-07082017-092202/.

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INTRODUÇÃO: Sabe-se que a doença periodontal é a doença infecciosa crônica mais prevalente na população adulta, acometendo 1/5 da população em fase ativa de trabalho e causadora de dor. As citocinas e demais substâncias moduladoras da inflamação que promovem e perpetuam a doença periodontal interagem e agravam outras doenças como o diabetes mellitus, aterosclerose e doenças autoimunes. O periodonto, com suas aferências proprioceptivas especializadas, desempenha importante papel de regulação dos movimentos da mastigação. Apesar da região orofacial ter uma ampla área de representação no córtex cerebral não se sabem os efeitos de uma inflamação crônica periodontal nesta representação. Ansiedade e estresse são conhecidos fatores correlacionados à doença periodontal e moduladores de condições dolorosas. Assim, são objetivos deste estudo a avaliação da sensibilidade mecânica em vibrissas, avaliação da ansiedade e o mapeamento do córtex motor de ratos com doença periodontal de 14 e 28 dias de evolução. MÉTODOS: Foram utilizados ratos Wistar machos pesando inicialmente entre 140 e 180 gramas, divididos em 3 grupos principais: grupo controle, grupo sham e grupo de estudo, em que a doença periodontal foi induzida por amarria no primeiro molar inferior direito. Os animais foram avaliados com 14 e 28 dias de doença, sendo a sensibilidade mecânica aferida por filamentos de Von Frey e a ansiedade avaliada por meio do labirinto em cruz elevado. O mapeamento do córtex motor foi realizado por estimulação elétrica epidural de um a dez volts. RESULTADOS: Ambos os períodos de evolução da doença causaram alterações condizentes com doença periodontal. Não houve diferenças no ganho de peso dos animais independente do grupo ao longo do estudo. Nos animais com 28 dias de doença houve maior nocicepção no lado doente com diferença estatística (p=0,042). Os animais do grupo de estudo 14 dias demonstraram mais comportamentos sugestivos de ansiedade nos parâmetros de congelamento (p=0,031), entradas nas extremidades dos braços abertos (p=0,048) e esticamento nos braços abertos (p=0,047) do labirinto em cruz elevado do que os grupos sham e controle. Os animais do grupo de estudo de 28 dias apresentaram maior comportamento de dor e medo observado através da presença do congelamento (p=0,016). O mapeamento do córtex motor evidenciou áreas representativas da mandíbula sobrepostas à área das vibrissas. Foi observada uma expansão da área da mandíbula no grupo da doença periodontal de 14 dias (p=0,038). CONCLUSÃO: A doença periodontal com 14 dias de evolução causou um aumento da resposta motora ipsilateral da mandíbula-mais-vibrissas e alterações de comportamento sugestivas de ansiedade<br>BACKGROUND: Periodontal disease is the most prevalent chronical infectious disease in adults, affecting 1/5 of people in active phase of labor and causing pain. Cytokines and substances that modulate inflammation promotes and perpetuate de periodontal disease, interacting and worsening other conditions such as diabetes mellitus, aterosclerosis and autoimmune diseases. The periodontium has specialized proprioceptive afferents and plays a role in the regulation of masticatory movements. Despite the wide brain cortical representation area of the orofacial structures, the periodontium has not been described in the literature and the effects of a chronical inflammation in its representation has not been clarified. Anxiety and stress are factors correlated to periodontal disease and modulators of pain. The aim of this study was evaluate vibrissae nociception through mechanical response, anxiety and the motor cortex mapping in rats with periodontal disease after 14 or 28 days of evolution. METHODS: Male Wistar rats (initial weight 140-180 grams) divided into 3 main groups: controls, sham and periodontal disease induced by placement of a cotton ligature in the mandibular right first molar tooth. The evaluations took place after 14 or 28 days of disease. Mechanical response was evaluated by von Frey filaments and anxiety was evaluated through the elevated plus maze. Epidural electrical stimulation (1 to 10 volts) was the method used for the cortical motor mapping. RESULTS: Both evolution periods caused clinical outcomes consistent to periodontal disease. There was no difference in the weight gain of the animals, whatever the group during the study. The animals with 28 days appeared to have a higher nociception in the side affected, with statistical difference (p=0.042). Animals with the disease evolution through 14 days showed more anxious behavior seen by freezing (p=0.031), entries in the extremities of open arms (p=0.048) and stretching in open arms (p=0.047) than the sham and control groups, in the elevated plus maze test. The 28 day disease evolution group showed more pain and fear behavior, seen by freezing (p=0.016). The cortical motor mapping showed an overlapping of jaw and vibrissae areas. There was an expansion of the mandibular area in the 14-day disease group (p=0.038). CONCLUSION: at 14-days, PD led to an expansion of the mandibular-plus-vibrissae motor cortical representation ipsilateral to the disease and behaviors suggestive of anxiety
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Jandial, Rahul. "Lineage mapping of brain tumors." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3306998.

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Thesis (Ph. D.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed June 30, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 125-137).
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Murtagh, Stefano. "Conformal Mapping and Brain Flattening." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/12273/.

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In this dissertation we study some of the main results concerning conformal mappings in the complex plane and between Riemann surfaces and we apply those results to the so-called brain flattening problem. In the first part of this thesis we prove the Riemann Mapping Theorem and we provide an introduction to the Uniformization Theorem for simply connected Riemann surfaces. The second part of the thesis is focused on the brain flattening problem, which deals with how to construct a conformal mapping from the brain's cortical surface to the unitary sphere. This procedure leads to a possible definition of the discrete mean curvature on a triangulated closed surface of genus zero. This flattening method has several applications in neuroscience.
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Gutierrez, Barragan Daniel. "Brain-wide mapping of fMRI network dynamics in the mouse brain." Doctoral thesis, Università degli studi di Trento, 2018. http://hdl.handle.net/11572/301211.

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Intrinsic brain activity has been widely characterized using the blood-oxygen-level-dependent(BOLD) functional Magnetic Resonance Imaging(fMRI)at rest. There is increasing interest in finding reproducible and robust signatures of large-scale brain synchronization, and pinpointing their neurophysiological substrates and inherent alteration in disease.In this respect, the implementation of dynamic fMRI mapping in laboratory animalsrepresents a major advance, offeringthe opportunity to unravel the elusive drivers of this phenomenon via the use of cell-type specific manipulations that are off limits in humans.Multiple investigations have shown that spontaneous brain activity is non-stationary andinvolves reconfigurationsinto multiple dynamicstates.This research describesa series of studies aimedto map spontaneous fMRI (rsfMRI) network dynamics in the resting mouse brain with voxel resolution. Starting from a proof-of-concept demonstration that canonical resting state fMRI correlations are reliably described by brief instances of regional peak fMRI activity, wedevised a novel frame-wise clustering strategy that allowed us to map recurrent fMRI networks states dynamicsin the mouse brain. We showthat brain-wide patterns of fMRI co-activation can be reliably mapped at the group and subject level, defining a restricted set of recurring brain states characterized by rich network structure. Of particular interest was the observation of opposite co-activation of the mouse default mode network (DMN) and Latero-cortical networks(LCN), two systems that have been proposed to parallel analogous systems of the human brain.Importantly, we also document that these functional states are characterized by contrasting patterns of spontaneous fMRI activity,and exhibit coupled oscillatory dynamics embedded in a common temporal reference marked by infra-slow global fMRI signal oscillations. We next applied this novel framework to a genetic modelof autismand show that aberrant patterns of fMRI connectivity in a genetic model of autism reflect the engagement non-canonical brain states, characterized by altered regional topography and oscillatory dynamics. We finally show that pharmacological stimulation of the cholinergic systems results in reduced large-scale brain synchronization, a finding associated with anew set of oscillating statesin which the involvement of basal forebrain areas is pre-dominant. Collectively,our result demonstrate the possibility of mapping spatio-temporal dynamics of spontaneous brain activity in the living mouse brain with voxel resolution. Our approach reveals a new set of fundamental principles guiding the spatiotemporal organization of resting state fMRI activity, and its disruption in brain disorders.
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Kirsch, Valerie. "Multimodal approaches in human brain mapping." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-146504.

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Holmes, Andrew Peter. "Statistical issues in functional brain mapping." Thesis, Connect to electronic version, 1994. http://hdl.handle.net/1905/193.

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Cho, Jae H. (Jae Hun). "Integrated and scalable molecular brain mapping." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/111262.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2017.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (pages 143-158).<br>Understanding the brain requires integrative knowledge of its cellular-, network-, and system-level architectures. Existing volume imaging techniques have proven the potential to provide such information, but the lack of technology to label large volumes for visualization has limited their utility. Here, we address this challenge by developing technologies -- stochastic electrotransport and SWITCH -- to extend multiplexed labeling methods to larger volumes. Stochastic electrotransport selectively expedites transport of molecular probes into the tissue without damaging it. SWITCH synchronizes the labeling reaction to achieve consistent and uniform labeling. These technologies are demonstrated by successfully visualizing several molecular markers in adult mouse brain tissues, which have been previously infeasible in time and cost. Although our focus is on neuroscience, the concepts and methods described in this thesis are quite general. Stochastic electrotransport will be applicable to any nonlinear transport problems, and SWITCH will be applicable to any problem requiring synchronization of reaction kinetics across long distances..<br>by Jae H. Cho.<br>Ph. D.
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Pavlicová, Martina. "Thresholding FMRI images." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1097769474.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xvii, 109 p.; also includes graphics (some col.) Includes bibliographical references (p. 107-109). Available online via OhioLINK's ETD Center
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Books on the topic "Brain Brain mapping. Rats"

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M, Crinella Francis, and Yu Jen, eds. Brain mechanisms in problem solving and intelligence: A lesion survey of the rat brain. Plenum Press, 1990.

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Duffau, Hugues, ed. Brain Mapping. Springer Vienna, 2011. http://dx.doi.org/10.1007/978-3-7091-0723-2.

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Spinelle, Diane E. Brain mapping and diseases. Edited by ebrary Inc. Nova Science, 2011.

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Maurer, Konrad, and Thomas Dierks. Atlas of Brain Mapping. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76043-3.

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Chen, Yu, and Babak Kateb, eds. Neurophotonics and Brain Mapping. CRC Press, 2017. http://dx.doi.org/10.1201/9781315373058.

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Swanson, Larry W. Brain maps: Structure of the rat brain. Elsevier, 1992.

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Alvarez-Bolado, G. Developmental brain maps: Structure of the embryonic rat brain. Elsevier, 1996.

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Roland, Per E. Brain activation. Wiley-Liss, 1993.

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D, Frith Christopher, ed. Mapping the mind. 2nd ed. University of California Press, 2010.

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Duffy, Frank H., Vasudeva G. Iyer, and Walter W. Surwillo. Clinical Electroencephalography and Topographic Brain Mapping. Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4613-8826-5.

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Book chapters on the topic "Brain Brain mapping. Rats"

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Yamada, Kiyofumi, Manh Hung Tran, Hyoung-Chun Kim, and Toshitaka Nabeshima. "Role of Inducible Nitric Oxide Synthase in β-Amyloid-Induced Brain Dysfunction in Rats." In Mapping the Progress of Alzheimer’s and Parkinson’s Disease. Springer US, 2002. http://dx.doi.org/10.1007/978-0-306-47593-1_21.

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Gonzalez-Lima, F. "Brain Imaging of Auditory Learning Functions in Rats: Studies with Fluorodeoxyglucose Autoradiography and Cytochrome Oxidase Histochemistry." In Advances in Metabolic Mapping Techniques for Brain Imaging of Behavioral and Learning Functions. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2712-7_2.

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Tyrer, Peter J., Mark Slifstein, Joris C. Verster, et al. "Brain Mapping." In Encyclopedia of Psychopharmacology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_4099.

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Mundale, Jennifer. "Brain Mapping." In A Companion to Cognitive Science. Blackwell Publishing Ltd, 2017. http://dx.doi.org/10.1002/9781405164535.ch4.

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Lasko, Wolf W. "Brain Mapping." In Die Kraft der Faszination. Gabler Verlag, 1995. http://dx.doi.org/10.1007/978-3-663-09731-0_10.

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Tonn, J. C. "Brain Mapping." In Practical Handbook of Neurosurgery. Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-84820-3_57.

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Genovese, C. R. "False Discovery Rate Control." In Brain Mapping. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-397025-1.00323-7.

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"Tumor." In Congress of Neurological Surgeons Essent, edited by Steven N. Kalkanis and Ganesh Rao. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780197534342.003.0006.

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This chapter focuses on neurosurgical oncology. The first set of studies explores various preoperative parameters that impact survival in patients with glioblastoma multiforme, identifies a cancer stem cell in human brain tumors, and demonstrates the importance of language mapping for glioma resection and its impact on functional outcomes. The second set of studies provides an analysis of the recurrence and progression of meningioma. The third set of studies evaluates the efficacy of surgery, whole-brain radiotherapy, and stereotactic radiosurgery in the treatment of patients with brain metastases. The last study, included for its historical value, is Dr. Simpson's paper in which he proposed a grading system for the recurrence rates of meningiomas but also the relationship between these rates and extent of resection of meningioma.
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Akella, Nirupama R. "At the Mercy of Facebook." In Socio-Cultural Influences on Teenage Pregnancy and Contemporary Prevention Measures. IGI Global, 2019. http://dx.doi.org/10.4018/978-1-5225-6108-8.ch008.

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This chapter is a meta-analysis of teen brain research and social media technology such as Facebook that could result in spiraling rates of teenage pregnancy. The author discusses contemporary theories of brain circuitry including teen brain structure and function as one of the plausible reasons for rising teenage pregnancy rates. The author argues that the challenge is to control the quality and influence of Facebook on teen behaviors, actions, and decisions to minimize the growing influence of social networking sites. In the conclusive section of the chapter, the author focuses on the expansion and extension of instructional and non-instructional physical activities, exergames, and active video games strategies to control the quality and influence of Facebook content by presenting research that advocates use of such activities and games within the Facebook interface. The author ends the chapter by mapping a future research direction of cross-cultural empirical investigation. The author wraps the chapter with a summative conclusion.
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RAKSHI, J. S., D. L. BAILEY, K. ITO, et al. "Methodology for Statistical Parametric Mapping of [ 18 F]Fluorodopa Uptake Rate Using Three-Dimensional PET 1 1Transcripts of the BRAINPET97 discussion of this chapter can be found in Section VIII." In Quantitative Functional Brain Imaging with Positron Emission Tomography. Elsevier, 1998. http://dx.doi.org/10.1016/b978-012161340-2/50018-4.

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Conference papers on the topic "Brain Brain mapping. Rats"

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Vasiliu, Laurentiu, Ilias Trochidis, Christoph Bussler, and Adamantios Koumpis. "RoboBrain: A software architecture mapping the human brain." In 2014 IEEE-RAS 14th International Conference on Humanoid Robots (Humanoids 2014). IEEE, 2014. http://dx.doi.org/10.1109/humanoids.2014.7041353.

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Chewpanyanun, Werawat, Mitsunori Matsumae, Tomohiko Horie, and Kuroda Kagayaki. "Heat Transfer Rates Mapping in The Brain based on DSC-MRI." In 2019 12th Biomedical Engineering International Conference (BMEiCON). IEEE, 2019. http://dx.doi.org/10.1109/bmeicon47515.2019.8990222.

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Ubeda, Andres, Jose M. Azorin, Nicolas Garcia, Jose M. Sabater, and Carlos Perez. "Brain-machine interface based on EEG mapping to control an assistive robotic arm." In 2012 4th IEEE RAS & EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob 2012). IEEE, 2012. http://dx.doi.org/10.1109/biorob.2012.6290689.

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Hasegawa, Ryo, Toshihiko Shiraishi, and Shin Morishita. "A Neural Networks Based on Structural Characteristics of Cerebral Neocortex." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-67213.

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Artificial neural networks have been applied to pattern recognition, prediction and control because they have abilities of learning, generalization and nonlinear mapping. These conventional neural networks have not had “intelligence” yet. In pattern recognition, the recognition rate can be low when there are some noises in recognized patterns. Not so many neural networks have been reported that introduce the structural and functional characteristics of the brain obtained by the progress of neurophysiology. In this study, we focused on the cerebral neocortex, which is the most developed in human to be compared with the other animals and deals with recognition, language and imagination, introduced its characteristics of uniform, hierarchical, column structures and six layers to neural networks and investigated the possibility of emerging its functional characteristics of the human brain.
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Schiecke, Karin, Andy Schumann, and Karl J. Baer. "Influence of Individual Heart Rate on Nonlinear Brain-Heart Interactions Estimated by Convergent Cross Mapping in Schizophrenic Patients and Healthy Controls." In 2020 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) in conjunction with the 43rd Annual Conference of the Canadian Medical and Biological Engineering Society. IEEE, 2020. http://dx.doi.org/10.1109/embc44109.2020.9175826.

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Valentino, D. J., J. C. Mazziotta, and H. K. Huang. "Mapping Brain Function To Brain Anatomy." In Medical Imaging II, edited by Roger H. Schneider and Samuel J. Dwyer III. SPIE, 1988. http://dx.doi.org/10.1117/12.968665.

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Studholme, Colin. "Fetal brain mapping." In 2012 IEEE 9th International Symposium on Biomedical Imaging (ISBI 2012). IEEE, 2012. http://dx.doi.org/10.1109/isbi.2012.6235593.

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Su, Zhengyu, Wei Zeng, Rui Shi, Yalin Wang, Jian Sun, and Xianfeng Gu. "Area Preserving Brain Mapping." In 2013 IEEE Conference on Computer Vision and Pattern Recognition (CVPR). IEEE, 2013. http://dx.doi.org/10.1109/cvpr.2013.290.

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Prophet, Jane. "(Projection) mapping the brain." In SA'15: SIGGRAPH Asia 2015. ACM, 2015. http://dx.doi.org/10.1145/2835641.2835645.

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Joshi, Sarang C., Michael I. Miller, Gary E. Christensen, Ayan Banerjee, Tom Coogan, and Ulf Grenander. "Hierarchical brain mapping via a generalized Dirichlet solution for mapping brain manifolds." In SPIE's 1995 International Symposium on Optical Science, Engineering, and Instrumentation, edited by Robert A. Melter, Angela Y. Wu, Fred L. Bookstein, and William D. K. Green. SPIE, 1995. http://dx.doi.org/10.1117/12.216420.

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Reports on the topic "Brain Brain mapping. Rats"

1

Wood, C. C., J. S. George, D. M. Schmidt, C. J. Aine, J. Sanders, and J. Belliveau. Human brain mapping: Experimental and computational approaches. Office of Scientific and Technical Information (OSTI), 1998. http://dx.doi.org/10.2172/674923.

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Kateb, Babak. IBMISPS (International Brain Mapping & Intraoperative Surgical Planning Symposium). Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada450740.

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Abou-Donia, M. B., W. A. Khan, H. B. Suliman, A. A. Abdel-Rahman, and K. F. Jensen. Combined Exposure to Pyridostigmine Bromide (PB), DEET, and Permethrin with Stress Increases Blood-Brain Barrier (BBB) Permeability and Inhibits Brain Acetycholinesterase in Rats. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada402063.

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Bloom, Alan S. Effects of Breast Cancer Chemotherapy Agents on Brain Activity in Rats: Functional Imaging Studies. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada544530.

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Vaishnav, Y. LLNLs Neurotechnology Portfolio Presentation to Society for Brain Mapping and Therapeutics (SBMT). Office of Scientific and Technical Information (OSTI), 2021. http://dx.doi.org/10.2172/1771029.

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Kochanek, Patrick M. Emergency Interventions After Severe Traumatic Brain Injury in Rats: Effect on Neuropatholgy and Functional Outcome. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada360938.

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Goldstein, L. B., A. M. Dechovskaia, S. Bullman, K. H. Jones, and A. A. Abdel-Rahman. Daily Dermal Co-Exposure of Rats to DEET and Permethrin Produces Sensorimotor Deficit, and Changes in Blood-Brain Barrier (BBB) and Blood-Testis Barrier (BTB). Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada402081.

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DeMar, James C., Miya I. Hill, Robert B. Gharavi, et al. Evaluation of Novel Polyunsaturated Fatty Acid Derived Lipid Mediators of Inflammation to Ameliorate the Deleterious Effects of Blast Overpressure on Eye and Brain Visual Processing Centers in Rats. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada606425.

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DeMar, James. Evaluation of Novel Polyunsaturated Fatty Acid Derived Lipid Mediators of Inflammation to Ameliorate the Deleterious Effects of Blast Over Pressure on Eye and Brain Visual Processing Centers in Rats. Defense Technical Information Center, 2015. http://dx.doi.org/10.21236/ada621266.

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Kateb, Babak. 5th Annual World Congress of IBMISPS on Brain Mapping & Image Guided Therapy held at The University of California, Los Angeles on 26-29 August 2008. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada497597.

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