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Dissertations / Theses on the topic 'Brain structure'

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1

Robinson, Emma Claire. "Characterising population variability in brain structure through models of whole-brain structural connectivity." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/5875.

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Models of whole-brain connectivity are valuable for understanding neurological function. This thesis seeks to develop an optimal framework for extracting models of whole-brain connectivity from clinically acquired diffusion data. We propose new approaches for studying these models. The aim is to develop techniques which can take models of brain connectivity and use them to identify biomarkers or phenotypes of disease. The models of connectivity are extracted using a standard probabilistic tractography algorithm, modified to assess the structural integrity of tracts, through estimates of white
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Dent, Myrna Alexandra Roberta. "Studies of brain chromatin structure." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315053.

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3

Popescu, Tudor. "The structure of the mathematical brain." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:a6f9fd8a-e753-439b-80da-8adb783cf12e.

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Humans have an innate ability to deal with numerosity and other aspects of magnitude. This ability is generally honed through education in and experience with mathematics, which necessarily changes the brain structurally and functionally. These changes can be further manipulated through non-invasive electrical brain stimulation. Studying these processes in the case of maths not only constitutes research of great practical impact – given the importance of numerical skills in today's society – but also makes use of maths as a suitable domain in which to study plasticity. In this thesis, I aimed
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Jonasson, Lars. "Aerobic fitness and healthy brain aging : cognition, brain structure, and dopamine." Doctoral thesis, Umeå universitet, Diagnostisk radiologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-139056.

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Background: Performing aerobic exercise and maintaining high levels of aerobic fitness may have positive effects on both brain structure and function in older adults. Despite decades of research however, there is still a rather poor understanding of the neurocognitive mechanisms explaining the positive effects of aerobic exercise on cognition. Changes in prefrontal gray matter as well as dopaminergic neurotransmission in striatum are both candidate neurocognitive mechanisms. The main aims of this thesis are: 1. To investigate the effects of aerobic exercise and fitness on cognition and magneti
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5

Saygin, Zeynep Mevhibe. "Structure-function relationships in human brain development." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/77843.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 2012.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis. Page 125 blank.<br>Includes bibliographical references.<br>The integration of anatomical, functional, and developmental approaches in cognitive neuroscience is essential for generating mechanistic explanations of brain function. In this thesis, I first establish a proof-of-principle that n
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Armstrong, Beth Diane. "Hippocampus: seahorse; brain-structure; spatial map; concept." Thesis, Rhodes University, 2010. http://hdl.handle.net/10962/d1002224.

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Through an exploration of both sculptural and thought processes undertaken in making my Masters exhibition, ‘Hippocampus’, I unpack some possibilities, instabilities, and limitations inherent in representation and visual perception. This thesis explores the Hippocampus as image (seahorse) and concept (brain-structure involved in cognitive mapping of space). Looking at Gilles Deleuze’s writings on representation, I will expand on the notion of the map as being that which does not define and fix a structure or meaning, but rather is open, extendable and experimental. I explore the becoming, rath
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7

Hunt, Benjamin A. E. "Individual differences and brain structure : correlates with magnetoencephalography." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/42738/.

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The work presented in this thesis aims to increase clinical capacity for magnetoencephalography (MEG) by developing an understanding of how, in healthy participants, individual differences in brain structure, personality, and demographics influence measurements of neural oscillatory responses and functional connectivity. To this end, a large cohort of normative data was acquired using MEG with additional data acquisition using high-field MRI and supplementary individual difference data collected via a psychometric battery and screening questionnaire. MEG data were analysed to elucidate both pr
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8

Bloom, Paul 1963. "Semantic structure and language development." Thesis, Massachusetts Institute of Technology, 1990. http://hdl.handle.net/1721.1/13686.

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9

Lind, Johanna. "Memory, genes, and brain imaging : relating the APOE gene to brain function and structure /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-110-4/.

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10

Morhardt, Ashley C. "Gross Anatomical Brain Region Approximation (GABRA): Assessing Brain Size,Structure, and Evolution in Extinct Archosaurs." Ohio University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1470743129.

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11

Zemanová, Lucia. "Structure-function relationship in hierarchical model of brain networks." Phd thesis, Universität Potsdam, 2007. http://opus.kobv.de/ubp/volltexte/2008/1840/.

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The mammalian brain is, with its numerous neural elements and structured complex connectivity, one of the most complex systems in nature. Recently, large-scale corticocortical connectivities, both structural and functional, have received a great deal of research attention, especially using the approach of complex networks. Here, we try to shed some light on the relationship between structural and functional connectivities by studying synchronization dynamics in a realistic anatomical network of cat cortical connectivity. We model the cortical areas by a subnetwork of interacting excitable neur
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12

Bellera, Carine. "Detecting heritability of brain structure using magnetic resonance imaging." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=31194.

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A method is described that allows one to assess heritability of brain structures using magnetic resonance images (MRI). We have obtained MRI images for a group of identical twins and another group of fraternal twins. Each MRI image was segmented into white and gray matter then smoothed to estimate white and gray matter density at each 3D image element or voxel. At each voxel, we use the intraclass correlations of the two groups in order to compute a 3D image of a measure of heritability, as well as a test statistic for detecting those regions with significant heritability. To our knowledge the
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黃德興 and Tak-hing Michael Wong. "Brain function and structure in violent metally abnormal offenders." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31981719.

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14

Ledig, Christian. "Robust multi-structure segmentation of magnetic resonance brain images." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/28959.

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Magnetic resonance (MR) imaging is a powerful technique for the non-invasive in-vivo imaging of the human brain. In this thesis several robust techniques are developed that allow the fully-automatic analysis of MR brain images. In particular an approach is presented that quantifies the volume of more than 100 individual structures within the whole brain. This methodology is extended to measure structural volume changes based on images acquired at multiple time points. The possibility to quantify volumetric change of numerous brain structures simultaneously sets the method apart from many estab
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15

Powell, Lauren Elizabeth. "The evolution of brain size and structure in primates." Thesis, Durham University, 2018. http://etheses.dur.ac.uk/12990/.

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The pressures and constraints influencing the wide variation in primate brain size and composition are hotly contested. Comparative biologists have proposed many alternative hypotheses with no consensus yet emerging. This thesis uses phylogenetic comparative techniques and new data to explore the core issues in primate brain evolution; examining how behavioural ecology is associated with brain size and structure variation and what life history correlates reveal about possible developmental mechanisms producing this variation. The thesis raises a number of important issues for the field. Firstl
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Bahuguna, Jyotika. "Structure-Dynamics relationship in basalganglia: Implications for brain function." Doctoral thesis, KTH, Beräkningsvetenskap och beräkningsteknik (CST), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-186262.

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In this thesis, I have used a combination of computational models such as mean field and spikingnetwork simulations to study various sub-circuits of basal ganglia. I first studied the striatum(chapter 2), which is the input nucleus of basal ganglia. The two types of Medium SpinyNeurons (MSNs), D1 and D2-MSNs, together constitute 98% of the neurons in striatum. Thecomputational models so far have treated striatum as a homogenous unit and D1 and D2 MSNs asinterchangeable subpopulations. This implied that a bias in a Go/No-Go decision is enforced viaexternal agents to the striatum (eg. cortico-st
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17

Smallman, Richard. "Schizotypy and the association with brain function and structure." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/schizotypy-and-the-association-with-brain-function-and-structure(c8f5a318-5a89-412d-b422-1eedb80e43f6).html.

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Introduction: Schizotypy is a personality trait that shares some of the characteristics of clinical disorders such as schizophrenia. Similarities are found in expression of psychotic-like experiences and presence of attenuated negative signs. Furthermore, schizotypal samples are associated with impairments in cognitive tasks, albeit in a less comprised form. For these reasons and others, schizotypy is considered a part of the extended-phenotype of schizophrenia and as such can be utilised as an analogue sample without some of theconfounds associated with illness. Objective: The aim of the PhD
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Wong, Tak-hing Michael. "Brain function and structure in violent metally abnormal offenders." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21254163.

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19

Powell, Howell William Robert. "Investigating brain structure and function in temporal lobe epilepsy." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1446099/.

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Background Anterior temporal lobe resection (ATLR) is increasingly used in the treatment of patients with refractory temporal lobe epilepsy (TLE). Complications of surgery include a decline in language and memory abilities, and visual field defects. The principal aim of this thesis was to use magnetic resonance imaging (MRI) techniques to improve the planning of effective surgical treatment for patients with TLE by using functional MRI to localise areas in the brain involved in language and memory function, and MR-tractography to investigate the structural connections of these areas and those
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20

Yanochko, Gina Marie. "Structure and function of the Drosophila protein Big Brain." Diss., The University of Arizona, 2001. http://hdl.handle.net/10150/279810.

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big brain is a neurogenic gene which, when mutated causes defects in cell fate determination during Drosophila neurogenesis through an unknown mechanism. The protein Big Brain (BIB) has sequence identity with the Major Intrinsic Protein family including the water- and ion-conducting Aquaporin channels. We show here that BIB expressed heterologously in Xenopus oocytes is a non-selective monovalent cation channel with permeability to K⁺ > Na⁺ >> TEA⁺. BIB macroscopic conductance, activated in response to endogenous oocyte signaling pathways, was decreased after treatment with 20μM insulin and w
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21

Ruiz, Susan Michelle Mosher. "Gender differences in brain function and structure in alcoholism." Thesis, Boston University, 2012. https://hdl.handle.net/2144/32050.

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Thesis (Ph.D.)--Boston University<br>PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Traditionally, alcoholism research focusing on the brain included only men. Recently, inclusion of women in brain-based alcoholism research has shown that gender differences in physiology and drinking habits
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22

AndÅ, Hiroshi. "Dynamic reconstruction and integration of 3D structure information." Thesis, Massachusetts Institute of Technology, 1993. http://hdl.handle.net/1721.1/12360.

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23

Smetters, Diana Kathryn. "Electronic structure and synaptic integration in corical neurons." Thesis, Massachusetts Institute of Technology, 1995. http://hdl.handle.net/1721.1/11887.

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24

Layton, Stuart Pope. "The temporal and bilateral structure of hippocampal replay." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/81730.

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Thesis (Ph. D. in Neuroscience)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 2013.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references.<br>The hippocampus is required for the formation, but not storage, of long-term episodic memories. During memory formation, however, the hippocampus is not a lone actor; rather it works in concert with various structures across the br
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Kim, John J. (John Jongwu). "Inflectional morphology and its interaction with word structure." Thesis, Massachusetts Institute of Technology, 1993. http://hdl.handle.net/1721.1/12487.

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26

Lai, Kam-ming. "Structure and function of 5'-nucleotidase of the rat brain /." [Hong Kong : University of Hong Kong], 1991. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12986343.

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27

黎錦明 and Kam-ming Lai. "Structure and function of 5'-nucleotidase of the rat brain." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1991. http://hub.hku.hk/bib/B31232280.

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28

Clavenstam, Isabell. "The Effect of Methamphetamine Abuse on Brain Structure and Function." Thesis, University of Skövde, School of Humanities and Informatics, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-3106.

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<p>The great amount of METH abuse all over the world causes enormous social and criminal justice problems. In the human brain the abuse of METH causes implications on both structures and functions given rise to acute as well as long term symptoms. In this essay the effects of METH abuse is described in the manner of the drug mechanism such as the impact on neurotransmitters, structural deficits with decreased and increased volumes and the implication on attention, memory, decision  making and emotions. Results from studies showing brain structural and cognitive impairments in METH abusers and
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Schirner, Michael [Verfasser]. "Bridging structure and function with brain network modeling / Michael Schirner." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2019. http://d-nb.info/1179778774/34.

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30

Thomas, Philip. "Structure-activity studies of ligands for brain nicotinic acetylcholine receptors." Thesis, University of Bath, 1995. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760682.

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31

Sweet, Andrew (Andrew Douglas). "Anomaly detection in brain connectivity structure : an application to epilepsy." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/79236.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 51-55).<br>In this thesis, we study approaches for detecting anomalous regions in brain connectivity networks estimated from resting state fMRI. We are motivated by the problem of localizing diseased regions to be resected in pre-surgical epilepsy patients. Our goal is to investigate the potential of these non-invasive connectivity approaches to augment and even replace the clinical gold standard fo
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Yoon, Young Gyu. "Optical and computational approaches for mapping brain activity and structure." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/118100.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2018.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 181-189).<br>Neuroscience always has been a heavily technology-starved field that has been often revolutionized with the rise of a new technology; and arguably the future advancement of neuroscience will also depend largely on the development of new technologies that allow acquiring new data sets that can provide deeper insights into the brain. While there is no universal agreement as to wh
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Arvidsson, Andrea. "Meditation, attention and the brain: function, structure and attentional performance." Thesis, Högskolan i Skövde, Institutionen för biovetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-15908.

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Meditation has been practiced around the world for thousands of years and has during the past decade become increasingly popular in the Western world. Meditation can be seen as a form of mental exercise and refers to a family of complex emotional and attentional regulatory practices that involves different attentional, cognitive monitoring and awareness processes. Clinical research on meditation has demonstrated that meditation seem to reduce stress, anxiety, and depression. Recent interest in how meditation affect the human brain and body have lead to an increase in research regarding the neu
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Moodley, Kuven K. "Multimodal studies of brain structure and function in neurodegenerative dementia." Thesis, University of Brighton, 2016. https://research.brighton.ac.uk/en/studentTheses/c0934e42-35ce-4293-a988-e2270e369718.

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Alzheimer’s disease (AD) is associated with a prodromal stage of cognitive decline, manifest clinically as mild cognitive impairment (MCI) that progresses ultimately to a stage of dementia. There is an urgent need to recognise AD at its earliest clinical stages, which entails distinguishing AD from other conditions, particularly other neurodegenerative diseases, but at a time when clinical symptoms are non-specific. Investigations such as neuropsychological testing and neuroimaging, using MRI and PET to determine changes in brain structure and metabolism respectively, provide additional useful
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Golesorkhi, Mehrshad. "The Brain's Intrinsic Spatiotemporal Structure and Its Potential Application in Artificial Intelligence." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/42211.

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Neuroscience focuses largely on how the brain mediates perception and cognition. However, this leaves open the basic organization and hierarchies of the brain’s neural activity by itself prior to and independent of its role in cognition. A recent model characterizes the brain’s intrinsic features in terms of temporo- spatial dynamical (rather than cognitive) terms – the brain’s spatiotemporal hierarchies shape what is called ‘brain’s intrinsicality’. The brain’s intrinsicality may provide potential applications in designing artificial intelligence (AI). In this dissertation, I explore ‘intrins
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Blunk, Aline D. (Aline Dorret). "Regulation of synaptic structure and function at the Drosophila neuromuscular junction." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/84874.

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Thesis (Ph. D. in Neuroscience)--Massachusetts Institute of Technology, Department of Brain and Cognitive Sciences, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Neuronal communication requires a spatially organized synaptic apparatus to coordinate neurotransmitter release from synaptic vesicles and activation of postsynaptic receptors. Structural remodeling of synaptic connections can strengthen neuronal communication and synaptic efficacy during development and behavioral plasticity. Here, I describe experimental approaches that have revealed how t
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Solé, Padullés Cristina. "Function and brain structure in aging with and without cognitive impairment." Doctoral thesis, Universitat de Barcelona, 2007. http://hdl.handle.net/10803/2705.

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L'interès general d'aquest projecte de tesi doctoral es centra en l'estudi dels patrons d'activació cerebral subjacents a l'envelliment cognitiu, tant en condicions clíniques normals com patològiques (Alteració cognitiva relacionada amb l'edat, alteració cognitiva lleu o Alzheimer inicial). Per aquest motiu hem empleat la tècnica de la RMf i hem estudiat com diferents variables intrínseques i extrínseques als individus estudiats influeixen la seva activació cerebral.<br/><br/>En un primer estudi ens vam plantejar l'estudi de les relacions entre el cervell i conducta en subjectes envellits amb
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Streitbürger, Daniel-Paolo. "Investigating Brain Structure Using Voxel-Based Methods with Magnetic Resonance Imaging." Doctoral thesis, Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-132638.

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The number of people suffering from neurodegenerative diseases, such as Alzheimer`s disease, increased dramatically over the past centuries and is expected to increase even further within the next years. Based on predictions of the World Health Organization and Alzheimer`s Disease International, 115 million people will suffer from dementia by the year 2050. An additionally increase in other age related neurodegenerative diseases is also forecasted. Quite naturally, neurodegenerative diseases became a focus of attention of governments and health insurances, trying to control the uprising financ
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Meier, Dominik Simon. "Structure-driven image-warping for anatomical labeling of the human brain /." The Ohio State University, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=osu148820217119762.

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Dickie, David Alexander. "Methods to assess changes in human brain structure across the lifecourse." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/10027.

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Human brain structure can be measured across the lifecourse (“in vivo”) with magnetic resonance imaging (MRI). MRI data are often used to create “atlases” and statistical models of brain structure across the lifecourse. These methods may define how brain structure changes through life and support diagnoses of increasingly common, yet still fatal, age-related neurodegenerative diseases. As diseases such as Alzheimer’s (AD) cast an ever growing shadow over our ageing population, it is vitally important to robustly define changes which are normal for age and those which are pathological. This wor
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Hu, Shiyan. "Automatic image analysis and structure segmentation for brain medial temporal lobe." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119386.

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In this thesis, two new automatic image segmentation techniques are proposed and used to analyze medical magnetic resonance (MR) images of human brain medial temporal lobes. The first segmentation technique is an adaptive multi-contrast MR image based appearance modeling scheme, which combines level set and active appearance modeling methods and incorporates multi-contrast MR images, into segmentation. The contribution of each multi-contrast image to the segmentation is established by the correlation between each multi-contrast test gray image and its corresponding synthesized gray image. The
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Yang, Zheyi. "Numerical methods to estimate brain micro-structure from diffusion MRI data." Electronic Thesis or Diss., Institut polytechnique de Paris, 2023. http://www.theses.fr/2023IPPAE016.

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L'imagerie par résonance magnétique de diffusion (IRM de diffusion) est une modalité d'imagerie non invasive couramment utilisée pour mesurer les propriétés micro-structurales des tissus biologiques au dessous de la résolution spatiale, en mesurant indirectement le déplacement de diffusion des molécules d'eau. En raison de la complexité géométrique du cerveau et du mécanisme complexe de l'IRM de diffusion, il est difficile de relier directement les signaux reçus à des paramètres biophysiques significatifs, tels que le diamètre des axones ou la densité. Ces dernières années, plusieurs modèles b
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Lee, Wei-Chung Allen. "Cellular and molecular analysis of neuronal structure plasticity in the mammalian cortex." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/34275.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 2006.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Includes bibliographical references (p. 87-100).<br>Despite decades of evidence for functional plasticity in the adult brain, the role of structural plasticity in its manifestation remains unclear. cpg15 is an activity-regulated gene encoding a membrane-bound ligand that coordinately regulates growth of apposing dendritic and axonal arbors and
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Isola, Phillip (Phillip John). "The Discovery of perceptual structure from visual co-occurrences in space and time." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/103203.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Brain and Cognitive Sciences, 2015.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 83-92).<br>Although impressionists assure us that the world is just dabs of light, we cannot help but see surfaces and contours, objects and events. How can a visual system learn to organize pixels into these higher-level structures? In this thesis I argue that perceptual organization reflects statistical regularities in the environment. When visual primitives occur together much more often than one would
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Ferguson, Stewart C. "Type 1 diabetes mellitus and the brain : influence of clinical complications and genetic factors on brain structure and cognitive function." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/29100.

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Microvascular disease, manifest as retinopathy, neuropathy or nephropathy, frequently complicates diabetes, the risk being related to long-term glucose control and increasing disease duration. Microvascular disease may also affect the cerebral circulation and could potentially compromise brain structure and intellectual performance. Type 1 diabetes commonly develops in childhood before maturation of the central nervous system and the developing brain may exhibit relative vulnerability to damage as a consequence of exposure to severe hypoglycaemia, or the development of Diabetic Keto-Acidosis,
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Bettinardi, Ruggero G. "Spontaneous brain activity: how dynamics and topology shape the emergent correlation structure." Doctoral thesis, Universitat Pompeu Fabra, 2016. http://hdl.handle.net/10803/395172.

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Neuroscienti c research in the last decades has revealed that ongoing brain activity exhibits highly structured spatio-temporal patterns of neural activations. The fundamental core of this endogenously generated correlation structure re ects, to a large extent, the complex anatomical organization of the central nervous system, whereas the variability of spontaneous brain activity is determined by regional properties. These cellular and circuit properties are in turn modulated either by external stimuli and ongoing computations as well as by signi cant changes in local dynamics due to
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González-Villà, Sandra. "Automated brain structure segmentation in magnetic resonance images of multiple sclerosis patients." Doctoral thesis, Universitat de Girona, 2019. http://hdl.handle.net/10803/667616.

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This thesis is focused on the automated segmentation of the brain structures in magnetic resonance images, applied to multiple sclerosis patients. This disease is characterized by the presence of lesions, which affect the segmentation result of commonly used automatic methods. We propose a new correspondence search model able to minimize this problem and extend the theory of two remarkable label fusion strategies of the literature, i.e. Non-local Spatial STAPLE and Joint Label Fusion, in order to integrate this model into their corresponding estimation algorithms. Furthermore, with the aim of
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48

Marshall, Christopher Douglas. "Evolutionary Significance of Brain Structure in the Florida Manatee (Trichechus manatus latirostris)." NSUWorks, 1992. http://nsuworks.nova.edu/occ_stuetd/355.

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The Florida manatee (Trichechus manatus latirostris) inhabits a unique aquatic niche. Adaptations to this niche include obligate herbivory, low metabolic rate, large body size, and supernumerary teeth. Consequences of these adaptations are, cold intolerance, low population rate of increase, and range restrictions. Manatee life history traits also have influenced brain evolution. In the past, examination of only gross anatomical brain structures in manatee brains have led to the fallacy that manatee brains are poorly developed. In order to answer questions about the internal structure of the Fl
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Filippini, Nicola. "Brain structure, function and connectivity associated with APOE genotype : what changes when?" Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.525306.

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50

Powell, R. C. "Evolution of the structure and function of vertebrate brain gonadotropin-releasing hormone." Master's thesis, University of Cape Town, 1986. http://hdl.handle.net/11427/27201.

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Abstract:
In this study, the structure and function of gonadotropin-releasing hormone (GnRH) in different vertebrate species, in the classes Aves, Reptilia and Pisces was investigated. Acetic acid extracts were subjected to gel filtration chromatography and semipreparative high performance liquid chromatography (HPLC) to partially purify the GnRHs. The GnRH immunoreactivity was then characterized by analytical HPLC, and by assaying HPLC fractions by radioimmunoassay with region-specific antisera generated against mammalian GnRH, Gln⁸-GnRH and Trp⁷,Leu⁸-GnRH and assessing luteinizing hormone (LH)-releasi
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