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Journal articles on the topic 'Brazilian green propolis'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Sun, Shengwei, Meijuan Liu, Jian He, Kunping Li, Xuguang Zhang, and Guangling Yin. "Identification and Determination of Seven Phenolic Acids in Brazilian Green Propolis by UPLC-ESI-QTOF-MS and HPLC." Molecules 24, no. 9 (2019): 1791. http://dx.doi.org/10.3390/molecules24091791.

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Brazilian green propolis is a complex mixture of natural compounds that is difficult to analyze and standardize; as a result, controlling its quality is challenging. In this study, we used the positive and negative modes of ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time of flight mass spectrometry in conjunction with high-performance liquid chromatography for the identification and characterization of seven phenolic acid compounds in Brazilian green propolis. The optimal operating conditions for the electrospray ionization source were capillary vol

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Salomão, Kelly, Eniuce M. de Souza, Andrea Henriques-Pons, Helene S. Barbosa, and Solange L. de Castro. "Brazilian Green Propolis: EffectsIn VitroandIn VivoonTrypanosoma cruzi." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–11. http://dx.doi.org/10.1093/ecam/nep014.

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The composition of a Brazilian green propolis ethanolic extract (Et-Bra) and its effect onTrypanosoma cruzitrypomastigotes and other pathogenic microorganisms have already been reported. Here, we further investigated Et-Bra targets inT. cruziand its effect on experimental infection of mice. The IC50/4 days for inhibition of amastigote proliferation was 8.5 ± 1.8 μg mL−1, with no damage to the host cells. In epimastigotes Et-Bra induced alterations in reservosomes, Golgi complex and mitochondrion. These effects were confirmed by flow cytometry analysis. In trypomastigotes, Et-Bra led to the los

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Scorza, Fulvio A., Antonio-Carlos G. de Almeida, Ana C. Fiorini, Carla A. Scorza, and Josef Finsterer. "Fighting eye diseases with Brazilian Green Propolis." Biomedicine & Pharmacotherapy 140 (August 2021): 111740. http://dx.doi.org/10.1016/j.biopha.2021.111740.

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Righi, A. A., G. Negri, and A. Salatino. "Comparative Chemistry of Propolis from Eight Brazilian Localities." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–14. http://dx.doi.org/10.1155/2013/267878.

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Propolis is a complex honeybee product with resinous aspect, containing plant exudates and beeswax. Their color, texture, and chemical composition vary, depending on the location of the hives and local flora. The most studied Brazilian propolis is the green (alecrim-do-campo) type, which contains mainly prenylated phenylpropanoids and caffeoylquinic acids. Other types of propolis are produced in Brazil, some with red color, others brown, grey, or black. The aim of the present work was to determine the chemical profiles of alcohol and chloroform extracts of eight samples of propolis, correspond

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Salatino, Antonio, Érica Weinstein Teixeira, Giuseppina Negri, and Dejair Message. "Origin and Chemical Variation of Brazilian Propolis." Evidence-Based Complementary and Alternative Medicine 2, no. 1 (2005): 33–38. http://dx.doi.org/10.1093/ecam/neh060.

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Propolis is a hive product containing chiefly beeswax and plant-derived substances such as resin and volatile compounds. Propolis has been used as an antiseptic and wound healer since ancient times and interest for the product has increased recently. Probably few plant species contribute as major resin sources. Green propolis derives mainly from vegetative apices ofBaccharis dracunculifolia(alecrim plants). However, wide variation detected in the chemical composition suggests contributions from alternative resin plant sources. Predominant components of the resin of green propolis are cinnamic

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Zhang, Chumei, Meijuan Liu, Zeyu Liang, Guanglign Yin, and Kunping Li. "HPLC fingerprinting and pattern recognition of Brazilian green propolis and Chinese propolis." IOP Conference Series: Earth and Environmental Science 332 (November 5, 2019): 032019. http://dx.doi.org/10.1088/1755-1315/332/3/032019.

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Yuan, Min, Xu-jiang Yuan, Miguel Pineda, et al. "A comparative study between Chinese propolis and Brazilian green propolis: metabolite profile and bioactivity." Food & Function 11, no. 3 (2020): 2368–79. http://dx.doi.org/10.1039/c9fo02051a.

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Búfalo, Michelle C., João M. G. Candeias, and José Maurício Sforcin. "In VitroCytotoxic Effect of Brazilian Green Propolis on Human Laryngeal Epidermoid Carcinoma (HEp-2) Cells." Evidence-Based Complementary and Alternative Medicine 6, no. 4 (2009): 483–87. http://dx.doi.org/10.1093/ecam/nem147.

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Propolis is a sticky dark-colored material showing a very complex chemical composition that honeybees collect from plants. It has been used in folk medicine since ancient times, due to several biological properties, such as antimicrobial, anti-inflammatory, antioxidant and immunomodulatory activities, among others. Its antitumor actionin vivoandin vitrohas also been reported, using propolis extracts or its isolated compounds. The goal of this work was to evaluate propolis's cytotoxic actionin vitroon human laryngeal epidermoid carcinoma (Hep-2) cells. These cells were incubated with different

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Shimazawa, Masamitsu, Satomi Chikamatsu, Nobutaka Morimoto, Satoshi Mishima, Hiroichi Nagai, and Hideaki Hara. "Neuroprotection by Brazilian Green Propolis againstIn vitroandIn vivoIschemic Neuronal Damage." Evidence-Based Complementary and Alternative Medicine 2, no. 2 (2005): 201–7. http://dx.doi.org/10.1093/ecam/neh078.

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We examined whether Brazilian green propolis, a widely used folk medicine, has a neuroprotective functionin vitroand/orin vivo.In vitro, propolis significantly inhibited neurotoxicity induced in neuronally differentiated PC12 cell cultures by either 24 h hydrogen peroxide (H2O2) exposure or 48 h serum deprivation. Regarding the possible underlying mechanism, propolis protected against oxidative stress (lipid peroxidation) in mouse forebrain homogenates and scavenged free radicals [induced by diphenyl-p-picrylhydrazyl (DPPH). In micein vivo, propolis [30 or 100 mg/kg; intraperitoneally administ

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Gao, Weina, Jianquan Wu, Jingyu Wei, et al. "Brazilian green propolis improves immune function in aged mice." Journal of Clinical Biochemistry and Nutrition 55, no. 1 (2014): 7–10. http://dx.doi.org/10.3164/jcbn.13-70.

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11

Peter, C. M., S. B. Waller, T. Picoli, et al. "Chemical and cytotoxic analyses of three varieties of Brazilian propolis (green propolis, jataí propolis and brown propolis) and its anti-Sporothrix brasiliensis in vitro activity." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 71, no. 3 (2019): 819–27. http://dx.doi.org/10.1590/1678-4162-9918.

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ABSTRACT In this study, we described the antifungal activity of three Brazilian propolis extracts: brown, green and from jataí bees against Sporothrix brasiliensis. The extracts were obtained from ethanolic extraction and their chemical composition was determined by high-performance liquid chromatography coupled to mass spectrometry. The cellular toxicity was measured in MDBK (Madin-Darby Bovine Kidney) cells and quantified by the MTT assay (3- (4,5 dimethylthiazol-2yl -2,5-diphenyl-2H bromine tetrazolato). For antifungal activity, the minimum inhibitory concentration (MIC) and minimum fungici

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Inokuchi, Yuta, Masamitsu Shimazawa, Yoshimi Nakajima, Shinsuke Suemori, Satoshi Mishima, and Hideaki Hara. "Brazilian Green Propolis Protects against Retinal Damage In Vitro and In Vivo." Evidence-Based Complementary and Alternative Medicine 3, no. 1 (2006): 71–77. http://dx.doi.org/10.1093/ecam/nek005.

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Propolis, a honeybee product, has gained popularity as a food and alternative medicine. Its constituents have been shown to exert pharmacological (anticancer, antimicrobial and anti-inflammatory) effects. We investigated whether Brazilian green propolis exerts neuroprotective effects in the retinain vitroand/orin vivo.In vitro, retinal damage was induced by 24 h hydrogen peroxide (H2O2) exposure, and cell viability was measured by Hoechst 33342 and YO-PRO-1 staining or by a resazurin–reduction assay. Propolis inhibited the neurotoxicity and apoptosis induced in cultured retinal ganglion cells

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Machado, Joleen Lopes, Anne Karine Martins Assunção, Mayara Cristina Pinto da Silva, et al. "Brazilian Green Propolis: Anti-Inflammatory Property by an Immunomodulatory Activity." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/157652.

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The immunomodulatory and anti-inflammatory activities of green propolis extracts fromApis melliferawere investigated using acute and chronic inflammation models. Swiss mice were anesthetized and a cotton pellet granuloma was implanted in subcutaneous tissue. Then the mice were divided into six groups and received apyrogenic water or different propolis extracts by oral route (5 mg/kg). According to the treatment the groups were designated as E1A, E1B, E10, E11, and E12. The control group received apyrogenic water. The treatment was performed by six days when the mice were killed. The blood and

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Trusheva, Boryana, Daniela Ivanova, Milena Popova, and Vassya Bankova. "Insights into the Essential Oil Compositions of Brazilian Red and Taiwanese Green Propolis." Natural Product Communications 12, no. 2 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200214.

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The objective of the present study was to characterize chemically the essential oils of two distinct propolis types: Brazilian red and Taiwanese green. Unlike the non-volatile chemical composition of these types of propolis, which has been extensively studied, the knowledge of the essential oils is scarce or even not investigated. The essential oils were obtained by hydrodistillation of raw propolis samples using a Likens-Nickerson type apparatus and then analyzed by GC/MS. The main volatile components of Brazilian red propolis were the phenylpropanoids: elemicin (26.1–27.5%), methyl eugenol (

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15

Moura, Sandra Aparecida Lima de, Mônica Alves Neves Diniz Ferreira, Silvia Passos Andrade, Maria Leticia Costa Reis, Maria de Lourdes Noviello, and Denise Carmona Cara. "Brazilian Green Propolis Inhibits Inflammatory Angiogenesis in a Murine Sponge Model." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–7. http://dx.doi.org/10.1093/ecam/nep197.

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Angiogenesis and inflammation are persistent features of several pathological conditions. Propolis, a sticky material that honeybees collect from living plants, has been reported to have multiple biological effects including anti-inflammatory and anti-neoplasic activities. Here, we investigated the effects of water extract of green propolis (WEP) on angiogenesis, inflammatory cell accumulation and endogenous production of cytokines in sponge implants of mice over a 14-day period. Blood vessel formation as assessed by hemoglobin content and by morphometric analysis of the implants was reduced b

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Jiang, Muzhou, Junjun Ni, and Zhou Wu. "Brazilian Green Propolis Suppresses Hypoxia-Induced Neuroinflammatory Responses in Microglia." Proceedings for Annual Meeting of The Japanese Pharmacological Society 92 (2019): 3—P—016. http://dx.doi.org/10.1254/jpssuppl.92.0_3-p-016.

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Chikaraishi, Yuichi, Hiroshi Izuta, Masamitsu Shimazawa, Satoshi Mishima, and Hideaki Hara. "Angiostatic effects of Brazilian green propolis and its chemical constituents." Molecular Nutrition & Food Research 54, no. 4 (2009): 566–75. http://dx.doi.org/10.1002/mnfr.200900115.

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Mikami, Norihisa, Hiroko Tani, Ryoji Kawakami, Atsushi Sugimoto, Shimon Sakaguchi, and Tomoki Ikuta. "Brazilian green propolis promotes TNFR2 expression on regulatory T cells." Food Science & Nutrition 9, no. 6 (2021): 3200–3208. http://dx.doi.org/10.1002/fsn3.2281.

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Xuan, Hongzhuan, Zhen Li, Jiying Wang, et al. "Propolis Reduces Phosphatidylcholine-Specific Phospholipase C Activity and Increases Annexin a7 Level in Oxidized-LDL-Stimulated Human Umbilical Vein Endothelial Cells." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/465383.

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To understand the mechanisms underlying the regulating dyslipidemia action of Chinese propolis and Brazilian green propolis, we investigated their effects on phosphatidylcholine-specific phospholipase C (PC-PLC) activity and annexin a7 (ANXA7) level which play crucial roles in the control of the progress of atherosclerosis. Furthermore, active oxygen species (ROS) levels, nuclear factor-KappaB p65 (NF-κB p65), and mitochondrial membrane potential (MMP) were also investigated in oxidized-LDL- (ox-LDL-) stimulated human umbilical vein endothelial cells (HUVECs). Our data indicated that the treat

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Franchi, Gilberto C., Cleber S. Moraes, Viviane C. Toreti, Andreas Daugsch, Alexandre E. Nowill, and Yong K. Park. "Comparison of Effects of the Ethanolic Extracts of Brazilian Propolis on Human Leukemic Cells As Assessed with the MTT Assay." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/918956.

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Propolis is a resinous product collected by honey bees. It was also reported that propolis has a wide variety of biological actions, including antimicrobial activity and antioxidant, anti-inflammatory, and suppressive effects of dioxin toxicity activities. The aim of this study was to compare the in vitro cytotoxic activities of green propolis (G12) and red propolis (G13) in human leukemia cells. These cells were incubated with different concentrations of propolis and 48 hours after the IC50was calculated for each cell. The results showed that the red propolis has cytotoxic effect in vitro hig

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Machado, Christiane Schineider, João Benhur Mokochinski, Tatiana Onofre de Lira, et al. "Comparative Study of Chemical Composition and Biological Activity of Yellow, Green, Brown, and Red Brazilian Propolis." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/6057650.

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The chemical composition and biological activity of a sample of yellow propolis from Mato Grosso do Sul, Brazil (EEP-Y MS), were investigated for the first time and compared with green, brown, and red types of Brazilian propolis and with a sample of yellow propolis from Cuba. Overall, EEP-Y MS had different qualitative chemical profiles, as well as different cytotoxic and antimicrobial activities when compared to the other types of propolis assessed in this study and it is a different chemotype of Brazilian propolis. Absence of phenolic compounds and the presence of mixtures of aliphatic compo

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Bhargava, Priyanshu, Debajit Mahanta, Ashish Kaul, et al. "Experimental Evidence for Therapeutic Potentials of Propolis." Nutrients 13, no. 8 (2021): 2528. http://dx.doi.org/10.3390/nu13082528.

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Propolis is produced by honeybees from materials collected from plants they visit. It is a resinous material having mixtures of wax and bee enzymes. Propolis is also known as bee glue and used by bees as a building material in their hives, for blocking holes and cracks, repairing the combs and strengthening their thin borders. It has been extensively used since ancient times for different purposes in traditional human healthcare practices. The quality and composition of propolis depend on its geographic location, climatic zone and local flora. The New Zealand and Brazilian green propolis are t

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Hori, Juliana I., Dario S. Zamboni, Daniel B. Carrão, Gustavo Henrique Goldman, and Andresa A. Berretta. "The Inhibition of Inflammasome by Brazilian Propolis (EPP-AF)." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/418508.

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Propolis extracts have gained the attention of consumers and researchers due to their unique chemical compositions and functional properties such as its anti-inflammatory activity. Recently, it was described a complex that is also important in inflammatory processes, named inflammasome. The inflammasomes are a large molecular platform formed in the cell cytosol in response to stress signals, toxins, and microbial infections. Once activated, the inflammasome induces caspase-1, which in turn induces the processing of inflammatory cytokines such as IL-1βand IL-18. So, to understand inflammasomes

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Missima, Fabiane, and José Maurício Sforcin. "Green Brazilian Propolis Action on Macrophages and Lymphoid Organs of Chronically Stressed Mice." Evidence-Based Complementary and Alternative Medicine 5, no. 1 (2008): 71–75. http://dx.doi.org/10.1093/ecam/nel112.

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Stress is a generic term that summarizes how psychosocial and environmental factors influence physical and mental well-being. The interaction between stress and immunity has been widely investigated, involving the neuroendocrine system and several organs. Assays using natural products in stress models deserve further investigation. Propolis immunomodulatory action has been mentioned and it has been the subject of scientific investigation in our laboratory. The aim of this study was to evaluate if and how propolis activated macrophages in BALB/c mice submitted to immobilization stress, as well

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Ni, Junjun, Zhou Wu, Jie Meng, et al. "The Neuroprotective Effects of Brazilian Green Propolis on Neurodegenerative Damage in Human Neuronal SH-SY5Y Cells." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–13. http://dx.doi.org/10.1155/2017/7984327.

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Oxidative stress and synapse dysfunction are the major neurodegenerative damage correlated to cognitive impairment in Alzheimer’s disease (AD). We have found that Brazilian green propolis (propolis) improves the cognitive functions of mild cognitive impairment patients living at high altitude; however, mechanism underlying the effects of propolis is unknown. In the present study, we investigated the effects of propolis on oxidative stress, expression of brain-derived neurotrophic factor (BDNF), and activity-regulated cytoskeleton-associated protein (Arc), the critical factors of synapse effica

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Ngatu, Nlandu R., Takao Saruta, Ryoji Hirota, et al. "Brazilian Green Propolis Extracts Improve Tinea pedis interdigitalis and Tinea corporis." Journal of Alternative and Complementary Medicine 18, no. 1 (2012): 8–9. http://dx.doi.org/10.1089/acm.2011.0696.

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de Albuquerque, Irineu Lima, Leonardo A. Alves, Telma L. G. Lemos, Conceioçã Aparecida Dorneles, and Manoel Odorico de Morais. "Constituents of the Essential Oil of Brazilian Green Propolis from Brazil." Journal of Essential Oil Research 20, no. 5 (2008): 414–15. http://dx.doi.org/10.1080/10412905.2008.9700044.

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Vaz Coelho, Luiz Gonzaga, Esther Margarida Alves Ferreira Bastos, Clarissa Carvalho Resende, et al. "Brazilian Green Propolis on Helicobacter pylori Infection. A Pilot Clinical Study." Helicobacter 12, no. 5 (2007): 572–74. http://dx.doi.org/10.1111/j.1523-5378.2007.00525.x.

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de Barros, Muriel Primon, João Paulo Barreto Sousa, Jairo Kenupp Bastos, and Sérgio Faloni de Andrade. "Effect of Brazilian green propolis on experimental gastric ulcers in rats." Journal of Ethnopharmacology 110, no. 3 (2007): 567–71. http://dx.doi.org/10.1016/j.jep.2006.10.022.

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Moise, Adela Ramona, and Otilia Bobiş. "Baccharis dracunculifolia and Dalbergia ecastophyllum, Main Plant Sources for Bioactive Properties in Green and Red Brazilian Propolis." Plants 9, no. 11 (2020): 1619. http://dx.doi.org/10.3390/plants9111619.

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Nowadays, propolis is used as a highly valuable product in alternative medicine for improving health or treating a large spectrum of pathologies, an ingredient in pharmaceutical products, and also as a food additive. Different vegetal materials are collected by honeybees and mixed with wax and other own substances in order to obtain the final product, called propolis. It is known as the bee product with the widest chemical composition due to the raw material collected by the bees. Different types are known worldwide: green Brazilian propolis (having Baccharis dracunculifolia as the major plant

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Yamaga, Masayuki, Hiroko Tani, Miyu Nishikawa, Keisuke Fukaya, Shin-ichi Ikushiro, and Kaeko Murota. "Pharmacokinetics and metabolism of cinnamic acid derivatives and flavonoids after oral administration of Brazilian green propolis in humans." Food & Function 12, no. 6 (2021): 2520–30. http://dx.doi.org/10.1039/d0fo02541k.

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Murase, Hiromi, Masamitsu Shimazawa, Mamoru Kakino, Kenji Ichihara, Kazuhiro Tsuruma, and Hideaki Hara. "The Effects of Brazilian Green Propolis against Excessive Light-Induced Cell Damage in Retina and Fibroblast Cells." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/238279.

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Background. We investigated the effects of Brazilian green propolis and its constituents against white light- or UVA-induced cell damage in mouse retinal cone-cell line 661W or human skin-derived fibroblast cells (NB1-RGB).Methods. Cell damage was induced by 3,000lx white light for 24 h or 4/10 J/cm2UVA exposure. Cell viability was assessed by Hoechst33342 and propidium iodide staining or by tetrazolium salt (WST-8) cell viability assay. The radical scavenging activity of propolis induced by UVA irradiation in NB1-RGB cells was measured using a reactive-oxygen-species- (ROS-) sensitive probe C

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Al-Hariri, Mohammed T., and Turki S. Abualait. "Effects of Green Brazilian Propolis Alcohol Extract on Nociceptive Pain Models in Rats." Plants 9, no. 9 (2020): 1102. http://dx.doi.org/10.3390/plants9091102.

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Pain is one of the most common symptoms encountered in the medical practice. None of the management procedures used currently offer a complete relief for patients suffering from nociceptive pain. New treatment strategies for pain management are needed. Propolis has been used in traditional medicine to relieve various types of pain. The aim of the current study was to investigate the potential effects of the green Brazilian propolis alcohol extract in vivo on the nociceptive and inflammatory pain models in rats. Rats were distributed into three random groups (n = 6); Group I: control group rece

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Moura, Sandra Aparecida Lima de, Giuseppina Negri, Antônio Salatino, et al. "Aqueous Extract of Brazilian Green Propolis: Primary Components, Evaluation of Inflammation and Wound Healing by Using Subcutaneous Implanted Sponges." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–8. http://dx.doi.org/10.1093/ecam/nep112.

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Propolis is a chemically complex resinous bee product which has gained worldwide popularity as a means to improve health condition and prevent diseases. The main constituents of an aqueous extract of a sample of green propolis from Southeast Brazil were shown by high performance liquid chromatography/mass spectroscopy/mass spectroscopy to be mono- and di-O-caffeoylquinic acids; phenylpropanoids known as important constituents of alcohol extracts of green propolis, such as artepillin C and drupanin were also detected in low amounts in the aqueous extract. The anti-inflammatory activity of this

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Senedese, Juliana Marques, Aline Rafaela Rodrigues, Michelle Andrade Furtado, et al. "Assessment of the Mutagenic Activity of Extracts of Brazilian Propolis in Topical Pharmaceutical Formulations on Mammalian CellsIn VitroandIn Vivo." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–7. http://dx.doi.org/10.1093/ecam/nen049.

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Propolis possesses various biological activities such as antibacterial, antifungal, anti-inflammatory, anesthetic and antioxidant properties. A topically applied product based on Brazilian green propolis was developed for the treatment of burns. For such substance to be used more safely in future clinical applications, the present study evaluated the mutagenic potential of topical formulations supplemented with green propolis extract (1.2, 2.4 and 3.6%) based on the analysis of chromosomal aberrations and of micronuclei. In thein vitrostudies, 3-h pulse (G1phase of the cell cycle) and continuo

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Barth, Ortrud Monika. "Melissopalynology in Brazil: a review of pollen analysis of honeys, propolis and pollen loads of bees." Scientia Agricola 61, no. 3 (2004): 342–50. http://dx.doi.org/10.1590/s0103-90162004000300018.

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This paper reviews current knowledge on the occurrence of several types of pollen grains in the sediments of honey samples, propolis and bee loads of Apiinae and Meliponinae in Brazil. After a short historical introduction about research activities in Melissopalynology using Brazilian samples, bee products were analyzed in respect to the greater Brazilian regions (South, Southeast, Northeast and North), emphasizing monofloral honeys and the green propolis. Numerous bibliographic references and a short glossary of the technical terms used is presented.

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Washio, Kohei, Mao Kobayashi, Natsuko Saito, Misato Amagasa та Hiroshi Kitamura. "Propolis Ethanol Extract Stimulates Cytokine and Chemokine Production through NF-κB Activation in C2C12 Myoblasts". Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/349751.

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Myoblast activation is a triggering event for muscle remodeling. We assessed the stimulatory effects of propolis, a beehive product, on myoblasts. After an 8 h treatment with 100 μg/mL of Brazilian propolis ethanol extract, expression of various chemokines, including CCL-2 and CCL-5, and cytokines, such as IL-6, increased. This propolis-induced cytokine production appears to depend on NF-κB activation, because the IKK inhibitor BMS-345541 repressed mRNA levels of CCL-2 by ~66%, CCL-5 by ~81%, and IL-6 by ~69% after propolis treatment. Supernatant from propolis-conditioned C2C12 cells upregulat

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Capistrano, Hermínia Marques, Eliene Magda de Assis, Rosana Maria Leal, Maria Eugênia Alvarez-Leite, Sylvie Brener, and Esther Margarida Alves Ferreira Bastos. "Brazilian Green Propolis Compared to Miconazole Gel in the Treatment ofCandida-Associated Denture Stomatitis." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/947980.

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Aim. To evaluate the efficacy of Brazilian green propolis in comparison to miconazole gel in the treatment ofCandida-associated denture stomatitis.Methods. Forty-five denture stomatitis patients, with palatal mucosa erythema levels classified according to Newtons’s criteria and with positive culture toCandidaspp., were randomly divided into three treatment groups: 15 received miconazole gel 2%, 15 received propolis gel 2,5%, and 15 received propolis 24% for mouthwash. After four daily use lasting two weeks, they were reexamined for the denture stomatitis degree and for a second culture ofCandi

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Wu, Zhou, Aiqin Zhu, Fumiko Takayama та ін. "Brazilian Green Propolis Suppresses the Hypoxia-Induced Neuroinflammatory Responses by Inhibiting NF-κB Activation in Microglia". Oxidative Medicine and Cellular Longevity 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/906726.

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Hypoxia has been recently proposed as a neuroinflammatogen, which drives microglia to produce proinflammatory cytokines, including interleukin-1β(IL-1β), tumor necrosis factor-α(TNF-α), and IL-6. Considering the fact that propolis has hepatoprotective, antitumor, antioxidative, and anti-inflammatory effects, propolis may have protective effects against the hypoxia-induced neuroinflammatory responses. In this study, propolis (50 μg/mL) was found to significantly inhibit the hypoxia-induced cytotoxicity and the release of proinflammatory cytokines, including IL-1β, TNF-α, and IL-6, by MG6 microg

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Carvalho, Claudemir de, Wesley Henrique Cabral Fernandes, Thays Barreto Freitas Mouttinho, Daniela Martins de Souza, Maria Cristina Marcucci, and Paulo Henrique Perlatti D’Alpino. "Evidence-Based Studies and Perspectives of the Use of Brazilian Green and Red Propolis in Dentistry." European Journal of Dentistry 13, no. 03 (2019): 459–65. http://dx.doi.org/10.1055/s-0039-1700598.

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AbstractThis review analyzes the evidence and perspectives of dental use of the green and red propolis produced in Brazil by Apis mellifera L. Multiple applications of propolis were found considering its antibacterial, antifungal, anti-inflammatory, immunomodulatory, antiviral, and healing properties. Its therapeutic effects are mainly due to the presence of alcohols, aldehydes, aliphatic acids, aliphatic esters, amino acids, aromatic acids, aromatic esters, flavonoids, hydrocarbyl esters, ethers, fatty acids, ketones, terpenes, steroids, and sugars. Propolis has been mainly used in dentistry

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Szliszka, Ewelina, Alicja Z. Kucharska, Anna Sokół-Łętowska, Anna Mertas, Zenon P. Czuba, and Wojciech Król. "Chemical Composition and Anti-Inflammatory Effect of Ethanolic Extract of Brazilian Green Propolis on Activated J774A.1 Macrophages." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–13. http://dx.doi.org/10.1155/2013/976415.

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The aim of this study was to investigate the chemical composition and anti-inflammatory effect of ethanolic extract of Brazilian green propolis (EEP-B) on LPS + IFN-γor PMA stimulated J774A.1 macrophages. The identification and quantification of phenolic compounds in green propolis extract were performed using HPLC-DAD and UPLC-Q-TOF-MS methods. The cell viability was evaluated by MTT and LDH assays. The radical scavenging ability was determined using DPPH•and ABTS•+. ROS and RNS generation was analyzed by chemiluminescence. NO concentration was detected by the Griess reaction. The release of

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Gomes, Henrique Albano Nogueira, Denilsa Pires Fernandes, Brenna de Sousa Barbosa, et al. "Brazilian green propolis doesn't have a beneficial effect on the cryopreservation of domestic cat epididymal spermatozoa." Research, Society and Development 10, no. 2 (2021): e48710212842. http://dx.doi.org/10.33448/rsd-v10i2.12842.

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This study evaluated the effect of different concentrations of Brazilian green propolis on the cryopreservation of epididymal sperm from domestic cats. Spermatozoa were collected from cauda epididymis by slicing technique in a TRIS extender, preheated to 37ºC. Then, the sperm were evaluated and divided randomly between the control group (without adding propolis in the extender) and the treatment groups (adding different concentrations of propolis extract in the extender): P1 (0.1 mg/mL), P2 (0.3 mg/mL) e P3 (0.6 mg/mL). Subsequently, sperm were cryopreserved. The evaluated parameters were sper

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Sun, Shengwei, Jian He, Meijuan Liu, Guangling Yin, and Xuguang Zhang. "A Great Concern Regarding the Authenticity Identification and Quality Control of Chinese Propolis and Brazilian Green Propolis." Journal of Food and Nutrition Research 7, no. 10 (2019): 725–35. http://dx.doi.org/10.12691/jfnr-7-10-6.

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Almeida-Junior, Silvio de, Danielle Vieira Pereira, Thuany Martins Ferreira, et al. "Anti-inflammatory and antinociceptive effects of kaempferide from the Brazilian green propolis." Research, Society and Development 9, no. 10 (2020): e1259108232. http://dx.doi.org/10.33448/rsd-v9i10.8232.

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The Brazilian green propolis is produced by Apis mellifera from Baccharis dracunculifolia. Kaempferide, which was isolated from green propolis and B. dracunculifolia is an O-methylated flavonol bearing gastroprotective, anti-allergic and anti-hypertensive activities. Thus, the aim of this study was to evaluate the anti-inflammatory and antinociceptive potentials of kaempferide, as well as its possible toxicological effect on kidney and liver. For that, nociception was assessed by thermal (hargreaves apparatus) and mechanical (Dynamic Plantar Aesthesiometer) sensitivities; anti-inflammatory pot

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de Figueiredo, Sonia M., Nancy S. Binda, Sidney A. Vieira-Filho, et al. "Physicochemical Characteristics of Brazilian Green Propolis Evaluated During a Six-Year Period." Current Drug Discovery Technologies 14, no. 2 (2017): 127–34. http://dx.doi.org/10.2174/1570163813666161220151425.

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Oda, Hirotake, Taneaki Nakagawa, Kosuke Maruyama, Yuzuru Dono, Hiroaki Katsuragi, and Soh Sato. "Effect of Brazilian green propolis on oral pathogens and human periodontal fibroblasts." Journal of Oral Biosciences 58, no. 2 (2016): 50–54. http://dx.doi.org/10.1016/j.job.2015.11.001.

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Wu, Z., Y. Liu, A. Zhu, S. Wu, and H. Nakanishi. "Brazilian green propolis suppresses microglia-mediated neuroinflammation by inhibiting NF-kB activation." Journal of the Neurological Sciences 381 (October 2017): 678. http://dx.doi.org/10.1016/j.jns.2017.08.1910.

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Silva-Beltrán, Norma Patricia, Ana Paola Balderrama-Carmona, Marcelo Andrés Umsza-Guez, and Bruna Aparecida Souza Machado. "Antiviral effects of Brazilian green and red propolis extracts on Enterovirus surrogates." Environmental Science and Pollution Research 27, no. 23 (2019): 28510–17. http://dx.doi.org/10.1007/s11356-019-07458-z.

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Ding, Jiangli, Tomoh Matsumiya, Ryo Hayakari, et al. "Daily Brazilian green propolis intake elevates blood artepillin C levels in humans." Journal of the Science of Food and Agriculture 101, no. 11 (2021): 4855–61. http://dx.doi.org/10.1002/jsfa.11132.

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Watanabe, Akio, Marília Oliveira de Almeida, Yusuke Deguchi, et al. "Effects of Baccharin Isolated from Brazilian Green Propolis on Adipocyte Differentiation and Hyperglycemia in ob/ob Diabetic Mice." International Journal of Molecular Sciences 22, no. 13 (2021): 6954. http://dx.doi.org/10.3390/ijms22136954.

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Propolis is a honeybee product with various biological activities, including antidiabetic effects. We previously reported that artepillin C, a prenylated cinnamic acid derivative isolated from Brazilian green propolis, acts as a peroxisome proliferator-activated receptor γ (PPARγ) ligand and promotes adipocyte differentiation. In this study, we examined the effect of baccharin, another major component of Brazilian green propolis, on adipocyte differentiation. The treatment of mouse 3T3-L1 preadipocytes with baccharin resulted in increased lipid accumulation, cellular triglyceride levels, glyce

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